Preparation method of traditional Chinese medicine for treating refractory pressure wound

Abstract

The invention relates to the technical field of pressure wound treatment, in particular to a preparation method of a traditional Chinese medicine for treating refractory pressure wound, which comprises the following steps: step 1, raw material preparation: selecting pig gall bladder, splitting the pig gall bladder, taking out pig bitter bile, and preparing quicklime and borneol as auxiliary medicines; step 2, bile sterilization: carrying out sterilization treatment on the pig bitter bile; 3, medicine mixing, wherein the sterilized pig bitter bile, quicklime and borneol are mixed and stirred to be uniform, and a mixed solution is formed; step 4, preparing a medicine: putting the mixed solution into a placement box, and then putting the placement box into an air drying device; and 5, medicine collection: collecting the air-dried mixed liquid powder to complete medicine preparation. According to the invention, the pig gall bladder is selected, the pig bitter bile is taken out, and then the borneol and the quick lime are mixed, so that the wound pressing medicine is prepared, the preparation cost of the wound pressing medicine is reduced, the economic burden of a patient is relieved, and the treatment enthusiasm of the patient is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of pressure sore treatment, and particularly relates to a preparation method of traditional Chinese medicine for treating intractable pressure sores. Background Art

[0002] With the advent of an aging society, the number of patients with chronic wounds such as diabetes, pressure sores, and non-healing after surgery has increased, and the demand for pressure sore drugs has continued to rise. Due to the long treatment cycle, high cost of chronic wound treatment, and the fact that patients are often accompanied by multiple underlying diseases, pressure sore drugs, as an important treatment means, have broad market potential.

[0003] Generally speaking, when medical staff treat chronic wounds, they often use Yunnan Baiyao for treatment. This treatment method has a high cost, and in the long-term use process, it will increase the economic burden of patients, thereby weakening the treatment enthusiasm of patients.

[0004] In summary, how to solve the problem of increasing the economic burden of patients and thus weakening the treatment enthusiasm of patients due to the long-term use of Yunnan Baiyao for treatment has become a technical problem that needs to be solved urgently by those skilled in the art. Therefore, it is necessary to propose a preparation method of traditional Chinese medicine for treating intractable pressure sores. Summary of the Invention

[0005] To solve the above problems, the present invention provides a preparation method of traditional Chinese medicine for treating intractable pressure sores. By selecting a pig gallbladder to take out pig bile, and then mixing borneol and quicklime, a pressure sore drug is made, which reduces the production cost of the pressure sore drug, reduces the economic burden of patients, and thus improves the treatment enthusiasm of patients.

[0006] To achieve the above object, the technical solution of the present invention is as follows: A preparation method of traditional Chinese medicine for treating intractable pressure sores, comprising the following steps:

[0007] Step 1, raw material preparation: Select a pig gallbladder, cut open the pig gallbladder to take out pig bile, and at the same time prepare quicklime and borneol as auxiliary drugs.

[0008] Step 2, bile sterilization: Sterilize the pig bile.

[0009] Step 3, mixing drugs: Mix the sterilized pig bile, quicklime and borneol and stir evenly to form a mixed solution.

[0010] Step 4, preparing drugs: Put the mixed solution into a placement box, then place the placement box in a drying device, use the air blowing component in the drying device to dry the mixed solution, continuously adjust the position of the placement box through the swinging component, and drive the air blowing component and the swinging component to move through the driving component.

[0011] Step Five, collecting the medicine: Collect the powdered mixture after air-drying to complete the preparation of the medicine.

[0012] The technical principle of the above solution is as follows: Pig bitter bile is cold in nature and has a significant effect of clearing heat and detoxifying. Components such as cholate and bilirubin in it have an inhibitory effect on some bacteria. Quicklime has strong alkalinity and can kill pathogenic microorganisms, and its powder can be used for external wound hemostasis. Borneol has the effects of anti-inflammatory, detumescence, clearing heat and relieving pain, and can also paralyze nerve endings to relieve pain, with a significant analgesic effect.

[0013] After sterilizing the pig bitter bile and mixing it with quicklime and borneol, the blowing component, swinging component and driving component work together to evenly air-dry the mixture.

[0014] Further, in Step One, the pig gallbladder is dissected to obtain pig bitter bile within two hours after selection.

[0015] Further, in Step One, quicklime and borneol are respectively ground into granular form, and the particle size is 0.1mm - 1mm.

[0016] Further, in Step Two, the sterilization treatment adopts the low-temperature pasteurization method, heating the pig bitter bile to 63°C and maintaining this temperature for 30 minutes.

[0017] Further, in Step Three, when mixing, first slowly add quicklime to the pig bile while stirring. After the quicklime and pig bile are fully mixed, then add borneol and continue stirring.

[0018] Further, the stirring method of the mixture adopts one or more of mechanical stirring, manual stirring and magnetic stirring.

[0019] Further, the air-drying device includes a box body, which is provided with an air inlet and an air outlet, and one side of the box body is detachably connected with a side plate.

[0020] The driving component includes a driving part and a controller. The controller is used to control the operation of the driving part. The driving part is fixedly connected inside the box body. The output shaft of the driving part is coaxially and fixedly connected with a first transmission wheel. A second transmission wheel is arranged inside the box body. Connecting rods are coaxially and fixedly connected to both sides of the second transmission wheel. The ends of the connecting rods far away from the second transmission wheel are all rotationally matched with the inner wall of the box body. A belt is tensioned between the first transmission wheel and the second transmission wheel.

[0021] Furthermore, the air blast assembly includes a cam fixedly connected to the side of the first transmission wheel remote from the driver, with a push rod eccentrically hingedly attached to the cam. A piston cylinder is fixedly connected to the housing, and the piston cylinder has an air inlet and an air outlet. Both the air inlet and the air outlet are fixedly connected to a one-way valve. The air outlet is fixedly connected to a gas pipeline, and the end of the gas pipeline remote from the air outlet is fixedly connected to the air inlet. The housing has an opening, and the air inlet is connected to the opening. A piston head is slidably fitted within the piston cylinder, and the end of the piston head remote from the air inlet is hingedly connected to the push rod.

[0022] Furthermore, a heating wire and a humidity sensor are fixedly connected in the gas transmission pipeline, and the controller is used to control the opening and closing of the heating wire and receive humidity data monitored by the humidity sensor.

[0023] Furthermore, the swing assembly includes a swing frame, the first connecting rods are fixedly connected to the swing frame, and the end of the swing frame away from the first connecting rod is fixedly connected to the swing plate. A sliding plate is slidably engaged with the box, the sliding plate has a plurality of grooves, the bottom of the sliding plate contacts the swing plate, and a plurality of springs are fixedly connected to the bottom of the sliding plate, and the ends of the springs away from the sliding plate are fixedly connected to the inner wall of the box.

[0024] The above scheme has the following beneficial effects:

[0025] 1. The present invention uses pig gallbladders and extracts pig bile as the main raw material, utilizing the heat-clearing and detoxifying properties of pig bile, as well as the antibacterial effects of components such as bile salts and bilirubin. The use of these natural ingredients not only aligns with the principles of traditional medicine but also potentially reduces the side effects of chemically synthesized drugs. Furthermore, low-temperature pasteurization of the pig bile effectively eliminates microbial contamination while preserving the active substances in the bile, ensuring the safety and effectiveness of the drug. The addition of quicklime and borneol, respectively, further enhances the efficacy of the drug by utilizing its alkalinity and anti-inflammatory, detumescent, and heat-clearing and analgesic properties.

[0026] 2. In the mixing and preparation process of the present invention, quicklime is first slowly added to the pig bile and fully stirred. After the reaction, borneol is added and stirred continuously. This step-by-step mixing method helps the full reaction and fusion between the components to form a mixed solution with specific pharmacological effects. At the same time, one or more of mechanical stirring, manual stirring and magnetic stirring are used for stirring, which can be flexibly selected according to actual conditions to ensure the uniformity and stability of the mixed solution.

[0027] 3. Through the cooperation of the cam, push rod, piston cylinder, one-way valve and air delivery pipeline, the present invention realizes the effective air drying of the mixed liquid. Among them, the design of the one-way valve ensures the one-way flow of gas and avoids the influence of gas backflow on the air drying effect. The swing assembly realizes the continuous swinging of the placement box through the cooperation of the swing frame, swing plate, sliding plate and spring, further improving the uniformity of the mixed liquid and the air drying effect.

[0028] Additional aspects and advantages of the present invention will be given in part in the following description, become apparent in part from the following description, or be learned through the practice of the present invention. Description of the Drawings

[0029] Figure 1 It is a process step diagram of the traditional Chinese medicine preparation method for treating intractable pressure sores of the present invention.

[0030] Figure 2 It is an axonometric view of the air drying device in the traditional Chinese medicine preparation method for treating intractable pressure sores of the present invention.

[0031] Figure 3 It is an axonometric view of the air blowing assembly and swing assembly in the traditional Chinese medicine preparation method for treating intractable pressure sores of the present invention.

[0032] Figure 4 It is a front sectional view of the air drying device in the traditional Chinese medicine preparation method for treating intractable pressure sores of the present invention.

[0033] The reference numerals in the accompanying drawings of the specification include: 1. Box body; 2. Side plate; 3. Driving motor; 4. Connecting rod; 5. Swing frame; 6. Swing plate; 7. Second transmission wheel; 8. Belt; 9. First transmission wheel; 10. Cam; 11. Push rod; 12. Piston cylinder; 13. Air inlet; 14. Air outlet; 15. Sliding plate; 16. Spring; 17. Piston head. Detailed Embodiments

[0034] The following is a further detailed description through specific embodiments:

[0035] Example 1:

[0036] As shown in the Figure 1 drawings: A traditional Chinese medicine preparation method for treating intractable pressure sores includes the following steps:

[0037] Step 1, raw material preparation: Select a pig gallbladder, cut open the pig gallbladder to take out the pig bile, and at the same time prepare quicklime and borneol as auxiliary medicines. The operation of cutting open the pig gallbladder to take out the pig bile is carried out within two hours after the pig gallbladder is selected. The quicklime and borneol are respectively ground into granular form, and the particle size is 0.1 mm - 1 mm.

[0038] Step 2, Bile Sterilization: Sterilize the pig gallbladder bile. The sterilization process uses the low-temperature pasteurization method, heating the pig gallbladder bile to 63°C and maintaining this temperature for 30 minutes.

[0039] Step 3, Mixing Medicines: Mix the sterilized pig gallbladder bile, quicklime, and borneol and stir evenly to form a mixed solution. When mixing, first slowly add the quicklime to the pig bile while stirring. After the quicklime and pig bile are fully mixed, then add the borneol and continue stirring. The stirring method of the mixed solution can be one or more of mechanical stirring, manual stirring, and magnetic stirring.

[0040] Step 4, Preparing Medicines: Load the mixed solution into a placement box, then place the placement box in a drying device. Use the air-blowing component in the drying device to dry the mixed solution, continuously adjust the position of the placement box through the swinging component, and drive the air-blowing component and the swinging component to move through the driving component.

[0041] Step 5, Collecting Medicines: Collect the dried mixed solution powder to complete the preparation of the medicine.

[0042] The specific implementation process is as follows: First, buy fresh pig gallbladders in the market, requiring that the pig gallbladders are intact and odorless. Cut open the pig gallbladders within two hours after purchase and take out the internal pig gallbladder bile. Subsequently, use the low-temperature pasteurization method to heat the pig gallbladder bile to 63°C and keep it at a constant temperature for sterilization for 30 minutes. Since the low-temperature pasteurization method is used and the temperature is relatively low during sterilization, the activity of the pig gallbladder bile can be retained while sterilizing.

[0043] Select high-quality and high-purity quicklime products, and select natural and impurity-free borneol varieties. Grind the quicklime and borneol separately until the particles have a diameter of 1 mm.

[0044] Subsequently, the quicklime can be added to the pig gallbladder bile for mixing. In this embodiment, mechanical stirring is used for mixing and stirring at a speed of 300 r / min. After the quicklime and pig gallbladder bile are fully mixed evenly, then add the borneol and continue to mix.

[0045] After the pig gallbladder bile, quicklime, and borneol are fully mixed, the mixed solution can be loaded into the placement box and then placed in the drying device. The placement box has good air permeability. Through the uniform air blowing of the air-blowing component, the evaporation of water in the mixed solution is accelerated. The swinging component continuously adjusts the position of the placement box to make each part of the mixed solution receive uniform air flow and avoid the situation of too fast or too slow local drying. The drying time is controlled within 24 hours.

[0046] After drying is completed, the mixed solution will be dried into particles. At this time, take out the placement box containing the particles, collect them and put them into a medicine bottle to complete the preparation operation of the medicine.

[0047] Embodiment 2:

[0048] As shown in the attached Figures 2 - 4 figure: The air-drying device includes a box body 1, an air inlet 13 and an air outlet 14 are opened on the box body 1, and a side plate 2 is detachably connected to one side of the box body 1.

[0049] As Figure 3 shown, the driving assembly includes a driving member and a controller. In this embodiment, the driving member is selected as a driving motor 3. The controller is used to control the operation of the driving motor 3. The driving motor 3 is bolted and fixedly connected inside the box body 1. The output shaft of the driving motor 3 is bolted and coaxially fixedly connected with a first transmission wheel 9. A second transmission wheel 7 is arranged inside the box body 1. Connecting rods 4 are bolted and coaxially fixedly connected to both sides of the second transmission wheel 7. The ends of the connecting rods 4 away from the second transmission wheel 7 are all rotationally matched with the inner wall of the box body 1. A belt 8 is tensioned between the first transmission wheel 9 and the second transmission wheel 7. The air-blowing assembly includes a cam 10. The cam 10 is bolted and fixedly connected to the side of the first transmission wheel 9 away from the driving motor 3. A push rod 11 is eccentrically hinged on the cam 10.

[0050] Combined with Figure 4 the figure shown, a piston cylinder 12 is bolted and fixedly connected inside the box body 1. An air inlet and an air outlet are opened on the piston cylinder 12. One-way valves are fixedly connected and communicated with the air inlet and the air outlet by screws. The air outlet is fixedly connected and communicated with an air delivery pipe by screws. The end of the air delivery pipe away from the air outlet is fixedly connected and communicated with the air inlet 13 by screws. An opening is opened on the box body 1. The air inlet is communicated with the opening. A piston head 17 is slidably fitted inside the piston cylinder 12. The end of the piston head 17 away from the air inlet is hinged to the push rod 11. An electric heating wire and a humidity sensor are fixedly connected by screws inside the air delivery pipe. The controller is used to control the opening and closing of the electric heating wire and receive the humidity data monitored by the humidity sensor. The swinging assembly includes a swinging frame 5. The first connecting rods 4 are all bolted and fixedly connected to the swinging frame 5. A swinging plate 6 is bolted and fixedly connected to the end of the swinging frame 5 away from the first connecting rod 4.

[0051] A sliding plate 15 is slidably fitted inside the box body 1. A plurality of grooves are opened on the sliding plate 15. The bottom of the sliding plate 15 is in contact with the swinging plate 6. A plurality of springs 16 are bolted and fixedly connected to the bottom of the sliding plate 15. The ends of the springs 16 away from the sliding plate 15 are all bolted and fixedly connected to the inner wall of the box body 1.

[0052] The specific implementation process is as follows: Taking Figure 2 and Figure 3For example, after the pig bile, quicklime, and borneol are fully mixed and loaded into the placement box, the medical staff can open the side plate 2, place the placement box into the groove on the sliding plate 15, and then the medical staff can control the driving motor 3 to start through the controller. After the driving motor 3 starts, it will drive the first transmission wheel 9 to rotate. When the first transmission wheel 9 rotates, it will drive the second transmission wheel 7 to rotate through the belt 8. As the second transmission wheel 7 rotates, the second transmission wheel 7 will drive the connecting rod 4 to rotate. As the connecting rod 4 rotates, the connecting rod 4 will drive the swing frame 5 to rotate, and through the rotation of the swing frame 5, the swing plate 6 is driven to make a semi-circular motion.

[0053] Take Figure 4 as an example. Since the sliding plate 15 is in contact with the swing plate 6, and several springs 16 are fixedly connected to the bottom of the sliding plate 15 by screws, when the swing plate 6 rotates upward, the sliding plate 15 will slide upward under the pushing action of the swing plate 6. When the swing plate 6 rotates downward, the sliding plate 15 will slide downward under the elastic force of the springs 16.

[0054] At the same time, during the rotation of the first transmission wheel 9, the cam 10 will be driven to rotate. As the cam 10 rotates, the push rod 11 will move up and down reciprocally. At this time, the piston head 17 will slide up and down along the piston cylinder 12 under the drive of the push rod 11. The outside air will enter the piston cylinder 12 through the opening and the air inlet, and then enter the air inlet 13 through the air outlet and the air outlet pipe to dry the placement box containing the mixed liquid.

[0055] Through the up and down reciprocating sliding of the sliding plate 15, the placement box can be fully dried by the wind at different angles, thereby improving the drying efficiency of the mixed liquid in the placement box. Through the humidity sensor, the medical staff can monitor the humidity of the air introduced into the air inlet 13. When the air humidity is high, the medical staff can control the heating wire to start through the controller to dry the air in the air inlet 13, further accelerating the drying efficiency of the mixed liquid and reducing the drug preparation time.

[0056] When the mixed liquid is dried and the drug needs to be taken out, the medical staff can control the swing plate 6 to tilt 45° through the driving motor 3. At this time, the sliding plate 15 is in an inclined state, and the end of the sliding plate 15 away from the side plate 2 is higher than the end close to the side plate 2, which is conducive to the medical staff opening the side plate 2 to take out the placement box and improving the efficiency of the medical staff in preparing drugs.

[0057] Obviously, the above embodiments are only examples for clear illustration and not limitations on the implementation manners. For those of ordinary skill in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation manners here. And the obvious changes or modifications derived therefrom are still within the protection scope of the present invention.

Claims

1. A preparation method of traditional Chinese medicine for treating intractable pressure sores, characterized in that, It includes the following steps: Step 1, raw material preparation: Select a pig gallbladder, cut open the pig gallbladder to take out the pig bitter bile, and at the same time prepare quicklime and borneol as auxiliary drugs; Step 2, bile sterilization: Sterilize the pig bitter bile; Step 3, mixing drugs: Mix the sterilized pig bitter bile, quicklime and borneol and stir evenly to form a mixture; Step 4, preparing drugs: Put the mixture into a placement box, then place the placement box in a drying device, dry the mixture through the air blowing component in the drying device, continuously adjust the position of the placement box through the swinging component, and drive the air blowing component and the swinging component to move through the driving component; Step 5, collecting drugs: Collect the dried mixture powder to complete the preparation of the drug.

2. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 1, characterized in that, In Step 1, the pig gallbladder is cut open to take out the pig bitter bile within two hours after selection.

3. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 2, characterized in that, In Step 1, quicklime and borneol are respectively ground into granular form, and the particle size is 0.1mm - 1mm.

4. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 3, characterized in that, In Step 2, the sterilization treatment adopts the low-temperature pasteurization method, heating the pig bitter bile to 63°C and maintaining this temperature for 30 minutes.

5. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 4, characterized in that, In Step 3, when mixing, first slowly add quicklime to the pig bile while stirring, and then add borneol and continue to stir after the quicklime and pig bile are fully mixed.

6. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 5, characterized in that, In Step 3, the stirring method of the mixture adopts one or more of mechanical stirring, manual stirring and magnetic stirring.

7. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 6, characterized in that, The drying device includes a box body (1), an air inlet (13) and an air outlet (14) are opened on the box body (1), and a side plate (2) is detachably connected to one side of the box body (1); The driving component includes a driving piece and a controller, the controller is used to control the operation of the driving piece, the driving piece is fixedly connected inside the box body (1), the output shaft of the driving piece is coaxially and fixedly connected with a first transmission wheel (9), a second transmission wheel (7) is arranged inside the box body (1), both sides of the second transmission wheel (7) are coaxially and fixedly connected with connecting rods (4), and the ends of the connecting rods (4) far away from the second transmission wheel (7) are rotatably matched with the inner wall of the box body (1); A belt (8) is tensioned between the first transmission wheel (9) and the second transmission wheel (7).

8. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 7, characterized in that, The air blowing component includes a cam (10), the cam (10) is fixedly connected to the side of the first transmission wheel (9) away from the driving piece, and a push rod (11) is eccentrically hinged on the cam (10); A piston cylinder (12) is fixedly connected inside the box body (1), an air inlet and an air outlet are opened on the piston cylinder (12), one-way valves are fixedly connected to both the air inlet and the air outlet, the air outlet is fixedly connected to an air conveying pipeline, and the end of the air conveying pipeline away from the air outlet is fixedly connected to the air inlet (13); An opening is opened on the box body (1), and the air inlet is communicated with the opening; A piston head (17) is slidably matched inside the piston cylinder (12), and the end of the piston head (17) away from the air inlet is hinged to the push rod (11).

9. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 8, characterized in that, An electric heating wire and a humidity sensor are fixedly connected inside the air conveying pipeline, and the controller is used to control the opening and closing of the electric heating wire and receive the humidity data monitored by the humidity sensor.

10. The traditional Chinese medicine preparation method for treating intractable pressure sores according to claim 9, characterized in that, The swinging component includes a swinging frame (5), the first connecting rods (4) are all fixedly connected to the swinging frame (5), and a swinging plate (6) is fixedly connected to the end of the swinging frame (5) away from the first connecting rods (4); A sliding plate (15) is slidably fitted inside a box body (1). A plurality of grooves are formed in the sliding plate (15). The bottom of the sliding plate (15) contacts a swing plate (6). A plurality of springs (16) are fixedly connected to the bottom of the sliding plate (15). One ends of the springs (16) far from the sliding plate (15) are fixedly connected to the inner wall of the box body (1).

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