Blood transfusion device, method and system for controlling blood transfusion dosage in perioperative period

Abstract

The invention provides a blood transfusion device, method and system for controlling the blood transfusion dosage in the perioperative period, and relates to the technical field of hematology. The blood transfusion device comprises a blood containing module used for containing blood needing to be injected into the body of a patient in the perioperative period; a display module is arranged on the blood containing module and used for displaying state data of blood in the blood containing module in real time; the state data are blood activity indexes and donor information data; the blood injection module is used for obtaining blood from the blood containing module and injecting the blood into the body of the patient; and the blood injection control module is used for controlling the operation of the blood injection module. According to the blood transfusion device, blood transfusion parameters can be accurately controlled, the blood transfusion efficiency and the resource utilization rate are improved, and the blood transfusion risk in the perioperative period is effectively reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of hematology, and in particular to a blood transfusion device, method and system. Background Art

[0002] Blood transfusion, a treatment method in which blood is administered intravenously to a patient, is widely used in clinical practice. Perioperative blood transfusion management is a crucial step in surgical procedures, but significant accuracy issues remain in current clinical practice.

[0003] Traditional transfusion strategies rely heavily on empirical assessments by healthcare professionals, failing to fully consider key factors: individual patient differences, such as the significant impact of different disease states, surgical procedures, intraoperative blood loss, and physiological characteristics on transfusion requirements. However, existing transfusion protocols often employ uniform standards, lacking a basis for individualized adjustments.

[0004] Secondly, blood storage time is associated with functional decline. For example, red blood cells can develop "storage lesion" during storage, manifesting as decreased 2,3-diphosphoglycerate (2,3-DPG) levels, ATP depletion, and increased oxygen affinity, leading to reduced oxygen release after transfusion. Studies have shown that tissue oxygen delivery efficiency of red blood cells stored for more than 14 days decreases by over 20% compared to fresh red blood cells. The dynamic impact of blood storage time is often overlooked in current transfusion processes.

[0005] Furthermore, blood flow rate significantly impacts transfusion effectiveness during a patient's transfusion. Excessively high blood flow rates can easily lead to hypothermia, circulatory overload, electrolyte and acid-base imbalances, and coagulation disorders. Excessively slow blood flow can lead to delayed correction of tissue hypoxia, blood clotting in the line, and increased transfusion risks. Choosing the appropriate blood flow rate is a pressing issue.

[0006] Chinese patent application CN119113282A discloses a blood transfusion device and method, comprising a main pipeline for transporting blood; a first branch pipeline, a first end of the first branch pipeline being connected to the end of the main pipeline, and a second end of the first branch pipeline being used to supply blood to a donor; a second branch pipeline, a first end of the second branch pipeline being connected to the end of the main pipeline; a bubble sensor disposed on the main pipeline and used to detect bubbles in the blood within the main pipeline; and a valve device that switches between a first state and a second state. When the valve device is in the first state, the blood in the main pipeline flows to the first branch pipeline, and when the valve device is in the second state, the blood in the main pipeline flows to the second branch pipeline. This invention application can more quickly eliminate bubbles in the blood flowing to the donor, thereby reducing the donor's ischemic time.

[0007] Chinese Patent CN206761984U discloses a blood transfusion device capable of automatically adjusting the blood transfusion flow rate, including a support rod, a telescopic rod, a blood transfusion tube and a base. The top of the support rod is provided with a telescopic rod, the top of the telescopic rod is installed with a connecting piece, one side of the connecting piece is provided with a fixed rod, the bottom of the fixed rod is provided with a fixed bracket, a storage bag is hung on the fixed bracket, the bottom end of the storage bag is provided with a blood transfusion tube, the blood transfusion tube is fixedly connected to the storage bag through a thick needle, a monitoring device is installed on the side of the blood transfusion tube, a flow meter is provided on one side of the monitoring device, the bottom end of the blood transfusion tube is provided with a thin needle, an adjustment knob and a control panel are provided on the side of the support rod, the bottom end of the support rod is provided with a support platform, a microprocessor is provided inside the support platform, and the bottom end of the support platform is provided with a base. This blood transfusion device further includes a wire winder and a water tank for containing warm water. The water tank is arranged on the base. A section of the blood transfusion tube is wound around the wire winder and immersed in the water tank filled with warm water. The wire winder is made of ceramic material. The patent application realizes the adjustment of the flow rate through the adjustment knob.

[0008] In the prior art, the error rate of the empirical estimation method is as high as 30%-40%, which may lead to insufficient blood transfusion or excessive blood transfusion. Therefore, there is an urgent need to establish a precise blood transfusion device based on multi-parameter dynamic evaluation, integrate real-time monitoring technology, so as to realize individualized blood management (Patient Blood Management, PBM) and improve the safety of blood transfusion during the perioperative period. Summary of the Invention

[0009] The purpose of the present invention is to overcome the deficiencies of the prior art, and provide a blood transfusion device, method and system for accurately determining the blood transfusion dosage during the perioperative period, realizing the accurate control of the blood transfusion dosage during the perioperative period, and improving the safety of blood transfusion during the perioperative period.

[0010] To achieve the above objectives, the present invention provides the following technical solutions: A blood transfusion device for controlling the blood transfusion dosage during the perioperative period, the device includes: a blood storage module for storing the blood that needs to be injected into the patient's body during the perioperative surgery; a display module is arranged on the blood storage module for real-time displaying the status data of the blood in the blood storage module; the status data is the activity index and source data of the blood; a blood injection module for obtaining blood from the aforementioned blood storage module and performing an injection operation into the patient's body; a blood injection control module for controlling the operation of the blood injection module.

[0011] Further, the blood storage module is provided with a fixed support component, a blood storage component and a voice interaction component. The storage component is provided with a plurality of blood storage chambers, and a gravity sensor is arranged at the bottom of each blood storage chamber; the voice interaction component is used to announce the volume of the infused liquid and / or the remaining liquid volume.

[0012] Furthermore, the blood injection module includes a plurality of blood injection components, which correspond to the aforementioned blood storage chambers one by one; the blood injection components include a puncture device, a pipeline washing chamber, a drip chamber, and an injection part, which are arranged in sequence on the catheter; one end of the catheter is connected to the blood bag, and the other end is connected to the injection part.

[0013] Furthermore, the blood injection component further includes a converter, which is sleeved on the end of the catheter and is used to implement the switching of different blood injection component paths.

[0014] Furthermore, the pipeline washing chamber is arranged above the drip chamber, and an injection port is arranged at the upper part of the pipeline washing chamber, and the washing liquid is injected from the injection port.

[0015] Furthermore, on the part of the catheter wrapped by the pipeline washing chamber, a plurality of penetration holes recessed into the pipe are provided for infiltrating the washing liquid into the catheter.

[0016] Furthermore, the pipeline washing chamber is arranged below the drip chamber, an injection port is arranged at the upper part of the pipeline washing chamber, and the washing liquid is injected from the injection port; on the part of the catheter wrapped by the pipeline washing chamber, a plurality of penetration holes shrinking into the pipe are provided for infiltrating the washing liquid into the catheter.

[0017] Furthermore, the blood injection control module is provided with a patient personal information collection and processing component, a blood information processing component, a patient infusion status analysis component, and an infusion mode execution component.

[0018] Furthermore, the patient personal information collection and processing component is used to collect the status data and / or physiological data of the patient during the perioperative period, and transmit the aforementioned physiological status data to the blood injection control module.

[0019] The present invention also provides a blood transfusion system for accurately controlling the blood transfusion dosage during the perioperative period, including a blood transfusion device for controlling the blood transfusion dosage during the perioperative period, which is used to provide a blood input function for controlling the blood volume; a vital sign monitoring device, which is used to monitor the vital signs of the patient and feedback the sign data to the blood transfusion device; a blood quality control unit: which is used to detect and control the quality of the blood to be transfused; and an intelligent terminal.

[0020] Due to the adoption of the above technical solutions, the present invention has the following advantages and positive effects: Accurately control blood transfusion parameters. Through the blood injection control module, the blood transfusion type, flow rate, and total amount are adjusted in real time, avoiding problems such as over-infusion and improper speed that may occur in traditional manual operations, and reducing the risk of blood transfusion-related complications.

[0021] Improve blood transfusion efficiency and resource utilization rate. Through automated operations, blood can be quickly obtained and transfused, shortening the response time for emergency blood transfusion and reducing waste of blood products.

[0022] Accumulate blood transfusion data to provide a basis for postoperative efficacy analysis and optimization of blood transfusion guidelines.

[0023] The blood transfusion device and method for precise blood transfusion dosage during the perioperative period provided by the present invention can reduce the blood transfusion harm to patients during the operation. The implementation of this technology will help improve our medical technology and equipment. Description of the Drawings

[0024] Figure 1 It is a schematic structural diagram of a blood transfusion device for controlling blood transfusion dosage during the perioperative period provided by an embodiment of the present invention, which is an embodiment.

[0025] Figure 2 It is a schematic structural diagram of a pipeline washing cabin provided by an embodiment of the present invention.

[0026] Figure 3 It is a working flowchart of a blood injection control module provided by an embodiment of the present invention.

[0027] Figure 4 It is a flowchart of a blood transfusion method for controlling blood transfusion dosage during the perioperative period provided by an embodiment of the present invention.

[0028] Figure 5 It is a schematic diagram of a blood transfusion system for controlling blood transfusion dosage during the perioperative period provided by an embodiment of the present invention.

[0029] Description of Reference Numerals: Blood transfusion device 100.

[0030] Blood storage module 200, first blood storage cabin 210, heat insulation board 211, second blood storage cabin 220, constant temperature component 221, gravity sensor 222, fixed support component 230, support rod 231, base 232, universal wheel 233, brake valve 234, voice interaction component 240, display module 250.

[0031] Blood injection module 300, pipeline washing cabin 310, injection port 311, penetration hole 312, drip funnel 320, flow rate control clamp 330, catheter 340, flow rate measurement component 350, stop clamp 360, converter 370, puncture needle 380, cleaning channel 390, cleaning steering valve 391.

[0032] Blood injection control module 400, patient personal information collection and processing component 410, blood information processing component 420, patient infusion status analysis component 430, and infusion mode execution component 440.

[0033] Blood transfusion system 500, vital sign monitoring device 510, blood quality control unit 520, intelligent terminal 530. Detailed Embodiments

[0034] The following further describes in detail the neural data measurement method, device, and system disclosed in the present invention in conjunction with the accompanying drawings and specific embodiments. It should be noted that the technical features or combinations of technical features described in the following embodiments should not be considered isolated, and they can be combined with each other to achieve better technical effects.

[0035] It should be noted that the structures, ratios, sizes, etc. shown in the drawings of this specification are only used to cooperate with the content disclosed in the specification for those familiar with this technology to understand and read, and are not used to limit the conditions for the invention to be implemented. Any modification of the structure, change in the proportional relationship, or adjustment of the size, without affecting the efficacy that the invention can produce and the purpose that can be achieved, should fall within the scope covered by the technical content disclosed in the invention. The scope of the preferred embodiments of the present invention includes additional implementations, in which the functions can be executed in a substantially simultaneous manner or in the reverse order according to the functions involved, rather than in the order described or discussed. This should be understood by those skilled in the technical field to which the embodiments of the present invention belong. Embodiment

[0036] Perioperative blood transfusion operations are crucial for saving patients' lives. Clinically, blood component transfusion is mainly used at present. When transfusing platelets, heating is not required. To reduce platelet aggregation, platelets need to be transfused first, followed by cryoprecipitate, which needs to be transfused within 30 minutes to prevent the destruction of factor VIII. Next are plasma and red blood cells, and these two components can be heated to about 37°C and transfused as constantly as possible at 37°C. During blood transfusion, the patient's reaction needs to be closely observed.

[0037] See Figure 1 The following shows a schematic structural diagram of a blood transfusion device for accurate blood transfusion dosage during the perioperative period provided by an embodiment of the present invention. A blood transfusion device 100 includes a blood storage module 200, a blood injection module 300, and a blood injection control module 400.

[0038] Preferably, the blood storage module 200 is provided with a plurality of blood storage chambers. According to the different temperature requirements of blood components, the blood storage chambers are divided into a first blood storage chamber 210 and a second blood storage chamber 220. An insulating board 211 is provided between the two blood storage chambers, and the insulating board 211 can be an environmentally friendly insulating material or a vacuum cavity.

[0039] The blood storage assembly corresponds to a plurality of blood storage chambers. The blood injection module includes a plurality of blood injection assemblies that correspond to the aforementioned blood storage chambers one by one. The blood injection assemblies are respectively used to transfuse one of whole blood, red blood cells, plasma, cryoprecipitate, platelets, or physiological saline.

[0040] By way of example and not limitation, the first blood storage chamber 210 is used for storing platelets and cryoprecipitate, and the second blood storage chamber 220 is used for storing plasma and red blood cells. On one side of the interior of the second blood storage chamber 220 away from the first blood storage chamber 210, a constant temperature component 221 is provided. Preferably, the constant temperature component 221 is a water bath component. With a gentle water bath, hemolysis can be better avoided.

[0041] At the bottom of each blood storage chamber, a gravity sensor 222 is provided for obtaining the usage amount of the liquid or the remaining weight data. At the same time, a voice interaction component is also provided, which can facilitate medical staff to understand the blood transfusion situation at any time.

[0042] By way of example and not limitation, the voice interaction component can be used to regularly report the blood usage amount and remaining amount, or it can be used by medical staff's questions such as "How much blood has been transfused?" "How much blood is left?" etc.

[0043] Preferably, the blood storage module 200 is provided with a fixed support component 230. The fixed support component 230 includes a support rod 231, a base 232, a universal wheel 233, and a brake valve 234.

[0044] By way of example and not limitation, the support rod 231 can adjust the height to adapt to different patients. The universal wheel 233 facilitates medical staff to move the device to a suitable position and fix it with the brake valve.

[0045] A display module 250 is provided on the blood storage module 200 for real-time displaying the status data of the blood in the blood storage module 200; the status data is the activity index and donor information data of the blood. By way of example and not limitation, the display module can be one of a liquid crystal screen, an LED screen, and an OLED screen. The display module 250 is electrically connected to the blood injection control module. The relevant data of the blood source is input into the blood injection control module, and the input method can be manual input or image recognition technology, such as reading and inputting information by QR code or recognizing and inputting information by picture.

[0046] By way of example and not limitation, the status data includes various activity indexes of the blood to be transfused, such as hemoglobin concentration, P 50 value, hemolysis rate, platelet count, pH value, factor VIII activity, etc. In addition, it also includes: blood donor information, such as the gender, age, genetic history, bad living habits, blood storage duration of the blood donor, etc.

[0047] Preferably, the display module 250 can real-time feedback the aforementioned information of the blood sample being transfused. In addition, it can also display information such as the blood flow rate, temperature, and stock volume for medical staff to view at any time.

[0048] Preferably, the blood injection assembly 300 includes a puncture device, a pipeline washing chamber 310, a drip chamber 320, and an injection member arranged in sequence on the catheter 340; one end of the catheter 340 is connected to a blood bag, and the other end is connected to the injection member.

[0049] The blood injection assembly further includes a converter 370 sleeved on the end of the catheter 340, and the converter 370 is used to switch different blood injection assembly passages. By way of example and not limitation, the converter 370 can be controlled by a solenoid valve. Specifically, after the platelet transfusion is completed, normal saline is used for cleaning. After the normal saline cleaning is completed, the solenoid valve automatically switches to the infusion of cryoprecipitate, and the blood injection assembly corresponding to the cryoprecipitate realizes the passage and starts the infusion.

[0050] By way of example and not limitation, a cleaning channel is provided in the converter 370. One end of the cleaning channel 390 is connected to the aforementioned catheter through a cleaning steering valve 391, and the other end leads to the outside. Specifically, during infusion, the cleaning steering valve blocks the connection between the cleaning channel 390 and the aforementioned catheter 340; when the catheter needs to be cleaned, the cleaning steering valve 391 connects the cleaning channel and the aforementioned catheter. The cleaning steering valve 391 can be operated through a cleaning operation knob.

[0051] See Figure 1 As shown, the puncture device is connected to the corresponding blood bag. The pipeline washing chamber 310 is arranged above the drip chamber 320. An injection port 311 is provided in the upper part of the pipeline washing chamber 310, and the washing liquid is injected from the injection port 311.

[0052] By way of example and not limitation, the washing liquid is normal saline. See Figure 2 As shown is a schematic structural diagram of the pipeline washing chamber provided by an embodiment of the present invention. In the part of the catheter wrapped by the pipeline washing chamber 310, a plurality of shrinkage pores 312 extending into the tube are provided for infiltrating the washing liquid into the catheter. Preferably, the inner diameter of the shrinkage pores 312 is 30-70 microns.

[0053] By way of example and not limitation, an elastic porous membrane, such as silica gel, etc., can be provided in the shrinkage pores 312; or, the part of the catheter wrapped by the pipeline washing chamber 310 is made of an elastic porous membrane material. When there is no pressure, the pores are naturally closed, and when pressed, the material is stretched to allow normal saline to pass through.

[0054] In actual use, medical staff inject normal saline into the pipeline washing chamber 310 through the injection port 311, and then squeeze the pipeline washing chamber 310, and the normal saline therein enters the catheter 340 through the shrinkage pores for flushing the tube.

[0055] By way of example and not limitation, a flow rate control clamp 330 is provided below the drip chamber 320 for medical staff to manually adjust the liquid flow rate.

[0056] Preferably, the injection part is a puncture needle 380, which can be connected to the indwelling needle of the patient. The puncture needle 380 is inserted into the center of the heparin cap of the indwelling needle to complete the connection. The indwelling needle is preferably a 20G indwelling needle. Or the puncture needle 380 is directly used for intravenous puncture.

[0057] See Figure 3 The schematic diagram of the blood infusion control module provided by the present invention is shown. The blood infusion control module 400 is provided with a patient personal information acquisition and processing component 410, a blood information processing component 420, a patient infusion status analysis component 430, and an infusion mode execution component 440.

[0058] Specifically, the patient personal information acquisition and processing component 410 acquires the general information of the patient, such as name, age, gender, personal medical history; physical examination information, such as height, weight, BMI value, waist circumference, blood pressure, etc.; laboratory examination information, such as blood routine examination, liver function examination and other required examination information.

[0059] The blood information processing component 420 is used to acquire the information of the standby blood, including information such as blood type, blood components, blood source, blood shelf life, etc.

[0060] The patient infusion status analysis component 430 is used to observe and analyze the changes in the physical characteristics of the patient during the infusion process. Images of the patient's face and limb parts are taken by a camera, and it is analyzed whether there are allergic reactions or other immune reactions such as flushing and rash in the captured images during the blood infusion process. Once an adverse reaction is found, the blood transfusion needs to be stopped in time and a standardized method is used for emergency treatment.

[0061] During actual operation, the blood infusion control module 400 makes a preliminary infusion mode setting according to the analysis results of the patient personal information acquisition and processing component 410 and the blood information processing component 420, including the pre-set flow rate and dosage of the infused blood.

[0062] During the infusion process, according to the analysis results fed back by the patient infusion status analysis component 430, the infusion mode execution component 440 adjusts the infusion placement in a timely manner and executes it.

[0063] Preferably, the infusion mode execution component calculates the infusion flow rate by the following formula :

[0064] Among them, ΔP is the pressure difference at both ends of the catheter, r is the inner diameter of the catheter, η is the apparent viscosity of the liquid, and different blood components have different apparent viscosities; L is the effective length of the catheter, and k c is the empirical calibration coefficient of the pipeline resistance.

[0065] Specifically, the value of the k c is related to factors such as the material and cleanliness of the catheter and is a property parameter of the catheter itself.

[0066] Case 1: Hepatectomy for adult patients. The patient weighs 70 kg, the central venous pressure is 10 mmHg, the HCT (hematocrit) is 40%, and the temperature is 24°C. A conventional catheter with a length of 1.5 m and an inner diameter of 2 mm is selected. The height h of the blood bag liquid level is 1.2 m, and the pipeline status: k c after washing is 0.92.

[0067] The calculation process is as follows: Calculate the dynamic pressure difference ΔP = ρgh - P venous , where ρ is the blood density taken as 1060 kg / m 3 , g is the acceleration due to gravity; h is the height of the blood bag liquid level; P venous is the central venous pressure, and P venous = 10 mmHg = 1333 Pa; Get

[0068] Calculate the blood viscosity η

[0069] η0 is the basic blood viscosity (at 37°C), HCT = 40%, e 2.5·HCT = e 2.5×0.4 = e 1 = 2.718; The temperature correction β T : At 24°C, the viscosity is 40% higher than at 37°C. Therefore, β T = 1.4.

[0070]

[0071] In summary,

[0072] After unit conversion, .

[0073] Set the blood viscosity correction parameter , when the storage time of the blood to be transfused increases, the blood viscosity will increase significantly. At this time, the corrected blood viscosity is ,

[0074] Among them, is 5 - 20%. This blood viscosity correction parameter mainly targets red blood cells. The shelf life of platelets is very short, and its influence can be temporarily ignored.

[0075] In the above embodiments, different blood components have different time nodes during storage, as shown in the following table:

[0076] Case Two: Emergency laparotomy for a young patient with traumatic massive hemorrhage Patient's personal information: Age / gender: 25 years old, male; Height / weight: 180 cm, 80 kg (BMI 24.6, robust) Blood routine: Hb was 110 g / L before surgery, and dropped to 60 g / L after acute blood loss during surgery, platelets 80×10 9 / L, INR was 1.8 (coagulopathy); Liver function: normal.

[0077] Blood to be transfused information: The blood is O - type suspended red blood cells (emergency blood transfusion), AB - type fresh frozen plasma (FFP), storage duration: red blood cells for 5 days (fresh), FFP for 30 days; Blood quality: no abnormality in red blood cells, FFP coagulation factor activity > 70% Predicted blood usage: Target Hb ≥ 70 g / L (permissive hypotension strategy), need to increase by 10 g / L. According to the trauma transfusion ratio (red blood cells: FFP: platelets = 1:1:1), it is estimated to transfuse 4 units of red blood cells + 4 units of FFP.

[0078] Dynamic adjustment: Supplement cryoprecipitate or platelets according to the results of thromboelastogram (TEG).

[0079] Flow rate setting: Massive hemorrhage mode: Initial flow rate 500 mL / h (pressurized transfusion), reduced to 200 mL / h after Hb stabilizes. Synchronous transfusion of FFP: 150 mL / 30 min (to avoid volume overload). FFP and red blood cells are transfused through different puncture holes.

[0080] For this case, the monitoring key points are blood gas analysis and analysis of coagulation function. Through the patient infusion status analysis component 430, continuously monitor the content of lactic acid and / or calcium ion Ca²⁺ in the user's blood, and re - check the patient's coagulation function every 1 hour. Feed the obtained results back to the blood injection control module 400. Correspondingly, the blood injection control module 400 adjusts the dosage and flow rate of the transfused blood according to the results.

[0081] The present invention also provides a blood transfusion method for controlling blood transfusion volume during the perioperative period, which includes the following steps: S01, collecting information to determine the blood volume and flow rate required by the patient at different stages of the perioperative period. Specifically, general information and laboratory test data of the patient are collected. The general information includes, but is not limited to: name, age, gender, medical history, living habits, eating habits, etc.; laboratory data includes blood routine, urine routine test data, liver function test data, and other test data required by the patient, and also includes the type of surgery of the patient, etc.

[0082] Subsequently, the blood volume and appropriate blood flow rate required by the patient during the perioperative period will be predicted based on the type of surgery and various information of the patient.

[0083] S02, performing a blood transfusion operation while recording the infusion status of the patient during the perioperative period to obtain infusion status parameters. During the perioperative period, there may be various risk factors, and the blood volume and / or flow rate required by the patient during this period may change.

[0084] Through observation or instruments, some changes in the patient's physical status can be obtained during blood transfusion, such as devices like cameras and ultrasonic devices. The infusion status parameters are the changes in the physical status and physiological indicators, including but not limited to changes in complexion, sudden arrest or rapidity of the pulse, skin allergic reactions, abnormal dilation or constriction of the pupils, increase or decrease in blood pressure and blood oxygen. When some of the above changes are captured, the corresponding components can give an alarm or broadcast information to promptly inform medical staff and reduce the blood transfusion risk during the operation.

[0085] Specifically, during the process of blood transfusion in the surgical period, when the circulatory system is overloaded, the patient will have manifestations such as sudden facial edema, jugular vein distension, and edema at the extremities, and may be accompanied by a sudden increase in systolic blood pressure, tachycardia, tachypnea, etc. The above manifestations and physiological data are in a negative correction state.

[0086] When the transfusion is too slow, the patient will have manifestations such as skin mottling, cold extremities, difficult-to-maintain blood pressure, increased lactic acid, and an enlarged range of intraoperative bleeding. The above manifestations are in a negative correction state.

[0087] S03, according to the analysis result of S02, when the infusion status parameter reaches the preset positive correction state, the blood volume is increased and the flow rate is increased; when the infusion status parameter reaches the preset negative correction state, the blood volume is decreased and the flow rate is decreased. By way of example and not limitation, medical staff can promptly stop the blood transfusion or change the flow rate to improve the safety of blood transfusion.

[0088] By way of example and not limitation, the positive correction state refers to the facial / limb manifestations, physiological signals of the patient, and the state at the surgical field collected by an image acquisition component such as a camera, a patient physiological information acquisition device such as an electrocardiogram machine, a blood pressure monitor, etc.

[0089] Specifically, when a patient who is receiving blood transfusion during surgery experiences a progressive increase in lactate, which is detected by the instrument in a timely manner and the lactate exceeds 4 mmol / L, at this time, the infusion state parameter is in the positive correction state, indicating tissue hypoxia. At this time, the doctor needs to increase the blood transfusion flow rate. When the vital sign monitoring device detects this phenomenon, it can timely feedback the data to the blood transfusion device and remind the doctor to timely correct the flow rate.

[0090] When it is detected that the systolic blood pressure of a patient receiving blood transfusion during surgery suddenly rises and exceeds 160 mmHg, the infusion state parameter is in the negative correction state, that is, the systolic blood pressure suddenly rises. Correspondingly, the medical staff needs to reduce the flow rate. When the vital sign monitoring device detects this phenomenon, it can timely feedback the data to the blood transfusion device and remind the doctor to timely correct the flow rate.

[0091] Specifically, according to the difference e between the target blood flow rate (set value) and the current actual blood flow rate, the PID controller is used to calculate the infusion flow rate correction coefficient α:

[0092] where α(t) is the infusion flow rate correction coefficient; ℯ(t) is the blood flow rate error, ; r is the target blood flow rate (set value) in mL / min; y is the current actual blood flow rate in mL / min; ; ; ; t is time, is the integral time variable in min.

[0093] The proportional term P term, , adjusts the infusion rate immediately according to the current deviation; the integral term term, helps to eliminate the influence of the long-term deviation of the blood flow rate and avoid the destruction of the system stability; the differential term D term, responds to the speed of the error change.

[0094] In specific implementation, by way of example rather than limitation, 4 blood transfusion components are provided in the embodiments of the present invention, which are respectively used for transfusing red blood cells, cryoprecipitate, plasma and platelets. Pressure sensors are provided at both ends of the catheter of each blood transfusion component, a flow rate sensor is provided on the outer surface of the catheter wall near the converter, and a timer and / or an alarm are also provided on the transfusion mode execution component 440.

[0095] See Figure 5 As shown, it is a schematic diagram of a blood transfusion system for precise blood transfusion dosage during the perioperative period provided by the embodiments of the present invention.

[0096] The blood transfusion device 100 for precise blood transfusion dosage during the perioperative period is used to provide the blood input function of precise blood transfusion volume. The vital sign monitoring device 510 is used to monitor various vital signs of the patient and timely feedback the sign data to the blood injection control module 400.

[0097] By way of example rather than limitation, the vital sign monitoring device 510 further includes devices such as a camera, which are used to collect the facial and / or limb images of the patient to assist medical staff in making judgments.

[0098] The blood quality control unit 520 is used to detect the quality of the blood to be input and perform short-term storage. The blood quality control unit 520 is provided with a cold storage room and a blood water bath tank. By way of example rather than limitation, the blood to be transfused can be stored or heated and thawed in the blood quality control unit 520. The blood quality information obtained by the blood quality control unit 520 will be fed back to the blood injection control module 400.

[0099] The blood injection control module 400 will make corresponding adjustments to the blood transfusion mode according to the data fed back by the vital sign monitoring device 510 and the blood quality control unit 520.

[0100] The system further includes an intelligent terminal: which is used to provide computing power and a terminal display tool. The intelligent terminal 530 can intuitively display the current blood transfusion situation, enabling medical staff to conveniently understand the situation of perioperative patients and reducing the blood transfusion risk.

[0101] For other technical features, see the foregoing embodiments and will not be elaborated herein.

[0102] Within the scope of the object of the present disclosure, the components can be selectively and operably combined in any number. Although exemplary aspects of the present disclosure have been described for illustrative purposes, those skilled in the art should be aware that the above description is only a description of the preferred embodiments of the present invention and does not limit the scope of the present invention in any way. The scope of the preferred embodiments of the present invention includes additional aspects, where functions may be performed in an order other than that presented or discussed. Any changes and modifications made by those of ordinary skill in the art based on the above disclosure fall within the scope of the claims.

Claims

1. A blood transfusion device for controlling blood transfusion dosage during perioperative period, characterized in that: The device includes: A blood storage module for storing the blood that needs to be injected into the patient during the perioperative surgery; a display module is provided on the blood storage module for real-time displaying the status data of the blood in the blood storage module; the status data is the activity index and donor information data of the blood; A blood injection module for obtaining blood from the aforementioned blood storage module and performing an injection operation into the patient's body; A blood injection control module for controlling the operation of the blood injection module.

2. The blood transfusion device according to claim 1, characterized in that: The blood storage module is provided with a fixed support component, a blood storage component, and a voice interaction component. The storage component is provided with a plurality of blood storage compartments, and a gravity sensor is provided at the bottom of each blood storage compartment; the voice interaction component is used to broadcast the volume of the infused liquid and / or the remaining liquid volume.

3. The blood transfusion device according to claim 2, wherein: The blood injection module includes a plurality of blood injection components, which correspond to the aforementioned blood storage compartments one by one; the blood injection components include a puncture device, a pipeline washing compartment, a drip chamber, and an injection part arranged in sequence on the catheter; one end of the catheter is connected to the blood bag, and the other end is connected to the injection part.

4. The blood transfusion device according to claim 3, characterized in that: The blood injection component further includes a converter sleeved on the end of the catheter for implementing the switching of different blood injection component passages.

5. The blood transfusion device according to claim 3, wherein: The pipeline washing compartment is arranged above the drip chamber, and an injection port is provided at the upper part of the pipeline washing compartment, and the washing liquid is injected from the injection port.

6. The blood transfusion device according to claim 3, characterized in that: In the part of the catheter wrapped by the pipeline washing compartment, a plurality of infiltration holes recessed into the pipe are provided for infiltrating the washing liquid into the catheter.

7. The blood transfusion device according to claim 1, wherein: The blood injection control module is provided with a patient personal information collection and processing component, a blood information processing component, a patient infusion status analysis component, and an infusion mode execution component.

8. The blood transfusion device according to claim 7, characterized in that: The patient personal information collection and processing component is used to collect the status data and / or physiological data of the patient during the perioperative period and transmit the aforementioned physiological status data to the blood injection control module.

9. A blood transfusion system for precise blood transfusion dosage during the perioperative period, characterized in that The system includes: a blood transfusion device for accurate blood transfusion dosage during the perioperative period, which provides a blood input function for controlling the blood transfusion volume; A vital sign monitoring device for monitoring the vital signs of the patient and feeding back the sign data to the blood transfusion device; A blood quality control unit: for detecting the quality of the blood to be input; And an intelligent terminal.

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