Oral mucosa extraction device for gene detection department

Abstract

The invention discloses an oral mucosa extraction device for a gene detection department, and belongs to the technical field of medical instruments. Aiming at the problems that the bending degree of the end of a swab is difficult to adjust during sampling at present, the matching degree is insufficient during use, and the sample size is insufficient due to improper operation during manual sampling, the oral mucosa extraction device comprises a shell, and an upper shell and a lower shell are arranged in the shell; the oral mucosa extraction device further comprises a swab end, a rotating mechanism, a pushing mechanism and an adjusting mechanism. The swab end is rotationally arranged at the bottom of the lower shell; the rotating mechanism is arranged at the center of the lower shell and is used for rotating the swab end to scrape oral mucosa cells, so that effective cell extraction is realized; the pushing mechanism is used for pushing the rotating mechanism to rotate, so that the operation process is more stable and controllable; the adjusting mechanism is connected with the upper shell, matched with the swab end and used for adjusting the radian of the swab end to adapt to oral cavity structures of different patients.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an oral mucosa extraction device for a genetic testing department. Background Art

[0002] With the rapid development of bioscience and technology, genetic testing technologies are increasingly being used in disease diagnosis, genetic disease screening, and personalized treatment. These applications often require high-quality genomic DNA as experimental material, and oral mucosal cells provide a convenient and safe source of genomic DNA. Oral mucosal sample collection offers the advantages of simplicity, non-invasiveness, and minimal pain, making it particularly suitable for infants, the elderly, patients with limited mobility, and those sensitive to pain. Furthermore, the oral mucosa contains a rich supply of exfoliated cells and DNA, providing sufficient sample volume for genetic testing. However, current methods for collecting oral mucosal samples still present certain technical challenges. Common oral swabs on the market are mostly disposable manual sampling tools that require the operator to manually control the scraping angle and force. This method has the following shortcomings: First, the angle and curvature of the swab are difficult to adjust, resulting in poor compatibility between different patient oral structures, affecting sampling quality; second, manual sampling can easily lead to insufficient or uneven sample extraction due to improper operation, affecting the accuracy of subsequent testing; and third, substandard sample storage methods pose the risk of contamination or degradation, compromising sample quality.

[0003] Therefore, there is an urgent need for an oral mucosal extraction device with a reasonable structure, convenient operation, strong adaptability and more reliable sample preservation, so as to improve the sampling efficiency and quality of genetic testing departments and meet the needs of clinical and scientific research for high-quality sample collection. Summary of the Invention

[0004] To address these issues, the present invention aims to provide an oral mucosal extraction device for use in genetic testing departments. Biting an airbag drives a propulsion mechanism, which in turn drives a rotation mechanism, which in turn drives a swab tip to scrape oral mucosal cells. This simple and efficient operation significantly reduces operational complexity for both patients and operators, enabling rapid cell extraction. Furthermore, an adjustment mechanism allows for flexible adjustment of the swab tip's angle to accommodate different patient oral structures, ensuring optimal contact between the swab tip and the oral cavity.

[0005] In order to achieve the above object, the technical solution adopted by the present invention is as follows: An oral mucosa extraction device for a genetic testing department comprises a housing, the housing comprising an upper housing and a lower housing, and further comprising: a swab tip rotatably disposed at the bottom of the lower housing for collecting oral mucosal cells for subsequent genetic testing operations; a rotating mechanism disposed at the center of the lower housing for rotating the swab tip to scrape oral mucosal cells; a pushing mechanism for pushing the rotating mechanism to rotate; and an adjusting mechanism connected to the upper housing and cooperating with the swab tip for adjusting the curvature of the swab tip.

[0006] Using this oral mucosa extraction device, the pushing mechanism drives the rotating mechanism to rotate stably. The rotating mechanism scrapes oral mucosal cells by rotating the swab tip. The adjusting mechanism can adjust the curvature of the swab tip according to the patient's oral structure to ensure that a sufficient number of oral mucosal cells are extracted to facilitate subsequent genetic testing operations.

[0007] Furthermore, an isolation piece is provided at the inner center of the lower shell, and the rotating mechanism is provided inside the isolation piece.

[0008] Furthermore, an airbag is provided between the lower shell and the isolation piece, and a tooth pad is provided on both sides of the airbag.

[0009] Furthermore, the rotating mechanism includes a rotating drum and a support rod; the rotating drum is movably arranged in the isolating member, and the rotating drum is connected to the swab end through a connecting rod; the support rod is rotatably arranged in the rotating drum.

[0010] The rotating mechanism enables the swab tip to rotate and move precisely through the interaction between the rotating cylinder and the support rod, thereby ensuring effective extraction of the oral mucosa.

[0011] Furthermore, the pushing mechanism includes two slides and two pushing rods; the two slides are arranged through the top of the lower shell; a pushing rod is movably provided in each slide, and the pushing rod is connected to the support rod.

[0012] The up and down movement of the push rod of the pushing mechanism can effectively drive the support rod to rotate, thereby driving the rotating mechanism to operate.

[0013] Furthermore, the upper shell is externally threadedly connected to the outer shell, and two sets of the adjustment mechanisms are provided between the upper shell and the outer shell.

[0014] Furthermore, the adjustment mechanism includes a connecting rod, a limit block and a connecting rope; the connecting rod movably passes through the upper shell; the limit block is connected to the top of the connecting rod, and the limit block is clamped with the top and outer shell of the upper shell; the connecting rope is connected to the bottom of the connecting rod, and movably passes through the lower shell to the center of the bottom.

[0015] The coordinated design of the shell and the adjustment mechanism allows the adjustment rod to move up and down by pulling the connecting rope, which can achieve precise angle adjustment to adapt to the oral structure needs of different patients.

[0016] Furthermore, the two connecting ropes are both connected to an adjusting rod at one end away from the connecting rod, and the adjusting rod is connected to a swab end at one end away from the connecting rope.

[0017] Furthermore, an arc-shaped tongue depressor is provided at the bottom of the lower shell.

[0018] The beneficial effects of the present invention are: 1. The extraction device of the present invention uses a biting airbag to drive a propulsion mechanism, which in turn drives a rotating mechanism, which in turn drives the swab tip to scrape oral mucosal cells. The operation process is simple and efficient, significantly reducing the operational complexity for patients and operators, and achieving rapid cell extraction. Furthermore, the adjustment mechanism can flexibly adjust the angle of the swab tip to adapt to different patients' oral structures, ensuring the optimal contact angle between the swab tip and the inner wall of the oral cavity, thereby improving sampling accuracy, comfort, and comprehensiveness.

[0019] 2. The extraction device of the present invention utilizes a push mechanism that drives the rotation mechanism by biting the airbag, thereby enabling the swab tip to precisely scrape oral mucosal cells, making the process extremely convenient. The patient simply bites the bite pad, compressing the airbag. The upward movement of the push rod activates the rotation mechanism, which in turn rotates the swab tip for sampling. This simple and straightforward operation significantly reduces operational complexity for both the patient and the operator, while achieving rapid and efficient cell extraction.

[0020] 3. The present invention's adjustable swab tip angle allows the device to adapt to different patient oral structures. Users can flexibly adjust the curvature of the swab tip as needed, ensuring it contacts the oral cavity at the optimal angle. This provides greater sampling accuracy and comfort, reduces discomfort caused by inappropriate angles, and improves the comprehensiveness and effectiveness of sampling.

[0021] 4. The provision of protective liquid and sterile tubes in the present invention can maintain the activity and integrity of the collected oral mucosal cells, prevent contamination, drying or degradation, thereby ensuring the high quality of the samples and providing reliable samples for subsequent genetic testing. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a structural schematic diagram of the extraction device in the present invention.

[0023] Figure 2 It is a side view of the extraction device of the present invention.

[0024] Figure 3It is a schematic structural diagram of the extraction device in the present invention from a top view.

[0025] Figure 4 This is a schematic diagram of the structure of the extraction device of the present invention without the sterile tube.

[0026] Figure 5 A side view of the extraction device of the present invention with the sterile tubing removed.

[0027] Figure 6 For the present invention Figure 5 Cross-sectional view of AA in the figure.

[0028] Figure 7 For the present invention Figure 6 A partial enlarged view of middle A.

[0029] Figure 8 For the present invention Figure 5 Cross-sectional view of the BB.

[0030] Figure 9 A side view of the extraction device of the present invention with the sterile tubing and housing removed.

[0031] Figure 10 For the present invention Figure 9 A partial enlarged view of B.

[0032] Figure 11 This is a schematic diagram of the structure of the extraction device of the present invention without the sterile tube, upper shell and lower shell.

[0033] Figure 12 This is a schematic diagram of the structure of the present invention with the upper shell removed.

[0034] Figure 13 It is a structural schematic diagram of the adjustment mechanism in the present invention.

[0035] Figure 14 It is a structural schematic diagram of the rotating mechanism in the present invention.

[0036] Figure 15 It is a structural schematic diagram of the rotary drum in the present invention.

[0037] Among them: 1. Shell; 2. Upper shell; 3. Lower shell; 4. Swab tip; 5. Rotating mechanism; 6. Pushing mechanism; 7. Adjusting mechanism; 8. Tongue depressor; 9. Sterile tube; 21. Outer shell; 31. Isolator; 32. Airbag; 33. Dental pad; 34. Groove; 51. Rotating cylinder; 52. Support rod; 53. Connecting rod; 54. Limiting groove; 61. Slide; 62. Pushing rod; 71. Connecting rod; 72. Limiting block; 73. Connecting rope; 74. Adjusting rod; 511. Slide; 521. Slide. DETAILED DESCRIPTION

[0038] In order to enable those skilled in the art to better understand the technical solution of the present invention, the technical solution of the present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0039] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "front end", "back end", "inside", "outside", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.

[0040] It should also be noted that, in the description of this application, unless otherwise expressly specified or limited, the terms "disposed," "installed," "connected," and "connected" should be understood broadly. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to direct connections, indirect connections through an intermediate medium, or internal connections between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on the specific circumstances.

[0041] Example 1: Refer to the attached Figure 1-15 The shown device is an oral mucosa extraction device for use in a genetic testing department, comprising a shell 1, in which an upper shell 2 and a lower shell 3 are provided. The oral mucosa extraction device also includes a swab end 4, a rotating mechanism 5, a pushing mechanism 6 and an adjusting mechanism 7; the swab end 4 is rotatably arranged at the bottom of the lower shell 3, for collecting oral mucosal cells for subsequent genetic testing operations; the rotating mechanism 5 is arranged at the center of the lower shell 3, for rotating the swab end 4 to scrape oral mucosal cells, thereby achieving effective cell extraction; the pushing mechanism 6 is used to push the rotating mechanism 5 to rotate, making the operation process more stable and controllable; the adjusting mechanism 7 is connected to the upper shell 2 and cooperates with the swab end 4 to adjust the curvature of the swab end 4 to adapt to the oral structure of different patients, so that a sufficient number of oral mucosal cells can be collected to facilitate subsequent genetic testing. It should be noted that the swab end 4 is made of elastic material to facilitate adjustment of the curvature of the swab end 4. The oral mucosa extraction device provides an efficient, stable and comfortable oral mucosa collection solution through the precisely designed rotating mechanism 5, pushing mechanism 6 and adjustment mechanism 7. The overall design enables the device to improve the patient experience while ensuring the extraction efficiency, is suitable for the oral conditions of different patients, and ensures the quality of the sample.

[0042] A spacer 31 is located at the center of the lower housing 3. The rotating mechanism 5 is housed within this spacer 31, isolating it from the lower housing 3 and facilitating the subsequent installation of the airbag 32. A recess 34 is defined at the bottom of this spacer 31, providing clearance for the lower end components of the rotating mechanism 5, preventing structural interference and improving smooth assembly and use. It should be noted that the spacer 31 can be a circular sleeve structure, isolating the rotating mechanism 5 from the gas in the airbag 32.

[0043] An airbag 32 is provided between the lower shell 3 and the isolation member 31, and a tooth pad 33 is provided on both sides of the airbag 32; the tooth pad 33 can make the patient more comfortable when biting; the lower shell 3 is provided with a groove 34 that cooperates with the tooth pad 33 to ensure that the tooth pad 33 is accurately positioned during the installation process, and the airbag 32 structure is firmly embedded. The setting of the airbag 32 can provide a certain degree of flexible support when the device is in use, preventing direct contact with the inner wall of the oral cavity to cause discomfort. The mouth pads on both sides of the airbag 32 can cooperate with the groove of the lower shell 3 to effectively fix the airbag 32 and ensure that the position of the airbag 32 is stable during use. The flexibility of the airbag 32 and the comfortable design of the tooth pad 33 provide patients with a gentler sampling experience, while ensuring the stability and efficiency of the sampling process.

[0044] The rotating mechanism 5 includes a rotating drum 51 and a supporting rod 52; the rotating drum 51 is movably arranged in the isolating member 31, and the rotating drum 51 serves as an intermediate transmission structure, and drives the swab end 4 through its rotation; the inner wall of the rotating drum 51 is provided with two arc-shaped sliding grooves 511, and the sliding grooves 511 serve as sliding guide channels for limiting the running trajectory of the internal sliding rod 521 to achieve arc motion; the rotating drum 51 is connected to the swab end 4 through a connecting rod 53, and a limiting groove 54 is provided at the bottom of the lower shell 3 to enable the connecting rod 53 to rotate, and the connecting rod 53 effectively transmits the rotational motion of the rotating drum 51 to the swab The swab tip 4 is configured to achieve precise scraping action. The limiting groove 54 limits the rotation angle of the swab tip 4 to prevent discomfort caused by excessive rotation. The support rod 52 is rotatably arranged within the rotating drum 51. Both sides of the support rod 52 are provided with sliding rods 521 that cooperate with the sliding groove 511. The sliding rods 521 are clamped in the sliding groove 511. When the support rod 52 moves up and down, the sliding rods 521 follow the movement within the sliding groove 511. Since the support rod 52 cannot rotate, the rotating drum 51, which is movably connected to the sliding rods 521, will rotate with the movement of the support rod 52, thereby driving the swab tip 4 to rotate. The rotating mechanism 5 precisely controls the movement of the swab tip 4, ensuring the stability and accuracy of the scraping action. Through the cooperation of the sliding groove 511 and the connecting rod 53, the rotating mechanism 5 can efficiently transmit rotational power, improve the accuracy of oral mucosal cell collection, and reduce the risk of improper operation. The design of the rotating mechanism 5 ensures stable rotation of the rotating drum 51 through the cooperation with the support rod 52, thereby driving the swab tip 4 to rotate effectively. The curved sliding groove 511 on the inner wall of the rotating drum 51 cooperates with the sliding rod 521 on the support rod 52 to limit the range and direction of rotation and ensure a stable sampling process.

[0045] The pushing mechanism 6 includes two slides 61 and two push rods 62; the two slides 61 are arranged on the top of the lower shell 3, and the slides 61 serve as guide channels for the push rods 62 and provide structural support for them; a push rod 62 is movably arranged in each slide 61, and the push rod 62 can move up and down to drive the support rod 52 to rotate, thereby driving the entire rotating mechanism 5 to rotate; the push rod 62 is connected to the support rod 52, so that the occlusal pad 33 pushes the push rod 62 to complete the scraping action of the swab tip 4, which is easy to operate, has a quick action response, and effectively improves the extraction efficiency. The pushing mechanism 6 drives the rotating mechanism 5 through the cooperation of the slides 61 and the push rods 62. The push rod 62 is connected to the support rod 52, so that the movement of the push rod 62 can drive the support rod 52 to move up and down. The slides 521 on both sides of the support rod 52 follow the movement in the slide groove 511, driving the rotating cylinder 51 to rotate, thereby driving the swab tip 4 to rotate for sampling. When the patient bites the bite pad 33 , the airbag 32 is compressed, causing the push rod 62 in the slide cylinder 61 to move upward, and the slide rod 521 moves along in the slide groove 511 , thereby driving the swab tip 4 to rotate.

[0046] The upper shell 2 is externally threadedly connected to the outer shell 21, and the thread of the outer shell 21 is designed to drive the up and down movement of the adjustment mechanism 7; two sets of the adjustment mechanism 7 are provided between the upper shell 2 and the outer shell 21. The arrangement of the adjustment mechanism 7 allows the user to flexibly adjust the angle of the swab end 4 as needed, thereby adapting to different oral morphologies.

[0047] An arc-shaped tongue depressor 8 is provided at the bottom of the lower shell 3 to press the tongue during extraction, thereby preventing the tongue from lifting up and blocking the scraping area during the extraction process, improving the visibility and accessibility of the extraction operation, and preventing the scraper head from accidentally touching the tongue surface, thereby enhancing the accuracy of extraction.

[0048] The bottom of the lower housing 3 is sheathed with a sterile tube 9 filled with a protective fluid for storing collected oral mucosal cells. This protective fluid maintains the activity and integrity of the extracted cells, preventing contamination, drying, or degradation, facilitating subsequent transport and genetic testing operations, and improving sample quality. This design effectively ensures the storage safety and quality of the collected samples, making the subsequent genetic testing process more accurate and reliable. Preferably, the lower housing 3 and sterile tube 9 are detachably connected by threads.

[0049] The working principle of the extraction device in this embodiment is as follows: first, the sterile tube 9 is removed, the front end of the device is placed in the patient's mouth, the tongue is pressed by the tongue depressor 8, the patient bites the tooth pad 33, the air bag 32 is compressed, and the push rod 62 in the slide 61 moves upward. The movement of the push rod 62 can drive the support rod 52 to move up and down, and the slide rods 521 on both sides of the support rod 52 follow the movement in the slide groove 511, driving the rotating drum 51 to rotate, and then driving the swab end 4 to rotate for sampling, so that oral mucosal cells are adhered to the swab end 4; the preservation liquid is filled into the removed sterile tube 9, and then the sterile tube 9 is installed at the front end of the lower shell 3.

[0050] Example 2 Based on the first embodiment, the second embodiment provides a specific structure of the adjustment mechanism 7, which includes a connecting rod 71, a limit block 72, and a connecting rope 73. The connecting rod 71 is movably provided in the upper shell 2 and serves as a support and guide element for the adjustment rope. The limit block 72 is connected to the top of the connecting rod 71, and the limit block 72 is engaged with the top of the upper shell 2 and the outer shell 21 to achieve the limiting and stable connection of the adjustment mechanism 7 and prevent loosening during use. The connecting rope 73 is connected to the bottom of the connecting rod 71 and movably passes through the lower shell 3 to the bottom center, so that the tension can be accurately transmitted to the swab tip 4. The design of the adjustment mechanism 7 provides great flexibility for the adaptability of the device. The user can adjust the angle of the swab tip 4 according to the patient's oral structure, thereby improving the extraction efficiency and comfort, and ensuring effective collection under various oral conditions.

[0051] The two connecting ropes 73 are connected to an adjustment rod 74 at one end away from the connecting rod 71. The adjustment rod 74 is used to further transmit the manual operating force to the swab end 4, thereby realizing dynamic adjustment of the curvature of the swab head. The adjustment rod 74 is connected to the swab end 4 at one end away from the connecting rope 73. Through this structure, the front end of the swab end 4 can be bent or restored during the extraction process, thereby improving the adaptability of the angle of contact with the inner wall of the oral cavity and improving the comprehensiveness and efficiency of sampling. When the housing 21 is rotated, because the limit block 72 is stuck on the top of the housing 21, when the housing 21 is rotated and raised, the connecting rod 71 moves up, pulling the connecting rope 73 up, and then pulling the adjustment rod 74 upward, thereby changing the angle of the swab end 4. When the housing 21 is rotated back again, under the rebound force of the swab end 4, the adjustment rod 74 follows and moves down, and the device is reset.

[0052] The working principle of the extraction device in this embodiment is as follows: after the sterile tube 9 filled with protective fluid is installed at the front end of the lower shell 3, when the shell 21 is rotated, the limit block 72 is stuck on the top of the shell 21, so that when the shell 21 is rotated and raised, the connecting rod 71 moves upward, pulling the connecting rope 73 upward, and then pulling the adjustment rod 74 upward, thereby changing the angle of the swab tip 4; when the shell 21 is rotated back again, the adjustment rod 74 follows and moves downward under the rebound force of the swab tip 4, and the device is reset. This process is repeated multiple times, and the swab tip 4 continues to deform and vibrate, causing the oral mucosal cells adhered to the swab tip 4 to fall off and be preserved in the protective fluid.

[0053] When the angle of the swab tip 4 does not match the patient's oral cavity, the housing 21 is rotated. Because the limit block 72 is stuck on the top of the housing 21, the housing 21 rotates and rises, and the connecting rod 71 moves upward, pulling the connecting rope 73 upward, and then pulling the adjustment rod 74 upward, thereby changing the angle of the swab tip 4. The patient then bites the tooth pad 33 to drive the swab tip 4 to rotate and extract oral mucosal cells.

[0054] Specific application cases: The quality and extraction method of the sample are key factors affecting the accuracy of genetic testing results. By performing PCR amplification, gene sequencing, gene chip analysis and other technical analyses on DNA extracted from oral mucosal cells, important information such as potential genetic disease risks, individual genetic variations, and drug metabolism capacity can be effectively detected. When oral mucosal cells need to be extracted for genetic testing, the specific application method of the oral mucosal extraction device for genetic testing departments in this application is as follows: The working principle of the extraction device in this embodiment is as follows: First, the doctor removes the sterile tube 9 and gently places the front end of the device into the patient's mouth. During this process, the tongue depressor 8 at the bottom of the device is used to press the patient's tongue to ensure that the tongue does not affect the sampling area. Under the doctor's guidance, the patient bites the tooth pad 33 in the device. At this time, the air bag 32 is compressed due to the pressure, thereby pushing the push rod 62 in the slide 61 to move upward, driving the internal slide 521 to follow the movement in the slide groove 511, further driving the swab tip 4 to rotate, scraping the mucosa in the patient's mouth, and ensuring that sufficient oral mucosal cells adhere to the swab tip 4 to facilitate the subsequent genetic testing operation. Next, the doctor adds protective liquid to the interior of the sterile tube 9 and then reinstalls it to the front end of the lower shell 3 of the device, preparing to collect the extracted oral mucosal cells to facilitate subsequent transportation and genetic testing operations, and to prevent contamination, drying or degradation that may cause genetic testing to be impossible or inaccurate test results.

[0055] Subsequently, when the outer shell 21 is rotated, since the limit block 72 is stuck in the top of the outer shell 21, when the outer shell 21 is rotated and raised, the connecting rod 71 moves upward, pulling the connecting rope 73 upward, and then pulling the adjustment rod 74 upward, thereby changing the angle of the swab end 4. This process is repeated many times, and the swab end 4 is constantly deformed and vibrated, causing the oral mucosal cells on the swab end 4 to fall off into the protective liquid for preservation. The protective liquid can maintain the activity and integrity of the oral mucosal cells, prevent contamination or degradation, and ensure the high quality and stability of the sample in the subsequent transportation and testing process to ensure the accuracy and reliability of the test results.

[0056] When the angle of the swab tip 4 does not match the patient's oral cavity, the housing 21 of the rotating device is rotated. Since the limit block 72 is stuck at the top of the housing 21, when the housing 21 is rotated and raised, the connecting rod 71 moves upward, pulling the connecting rope 73 upward, and then pulling the adjusting rod 74 upward, thereby changing the angle of the swab tip 4 to make it more consistent with the structure of the patient's oral cavity. When the contact angle between the swab tip 4 and the inner wall of the patient's oral cavity is adjusted to the optimal angle, the patient bites the tooth pad 33 to drive the swab tip 4 to rotate to extract oral mucosal cells.

[0057] The basic principles, main features, and advantages of the present invention are shown and described above. Those skilled in the art should understand that the present invention is not limited to the foregoing embodiments. The foregoing embodiments and descriptions are merely illustrative of the principles of the present invention. Various changes and modifications may be made to the present invention without departing from the spirit and scope of the present invention. Such changes and modifications are intended to fall within the scope of the present invention. The scope of protection claimed in the present invention is defined by the appended claims and their equivalents.

Claims

1. An oral mucosa extraction device for a genetic testing department, comprising a housing (1), wherein the housing (1) comprises an upper housing (2) and a lower housing (3), characterized in that: Also includes: A swab tip (4) is rotatably disposed at the bottom of the lower housing (3) and is used to collect oral mucosal cells for subsequent genetic testing operations; A rotating mechanism (5) is provided at the center of the lower housing (3) and is used to rotate the swab tip (4) to scrape oral mucosal cells; A pushing mechanism (6) is used to push the rotating mechanism (5) to rotate; The adjustment mechanism (7) is connected to the upper shell (2) and cooperates with the swab end (4) to adjust the curvature of the swab end (4).

2. The oral mucosa extraction device for genetic testing according to claim 1, characterized in that: An isolation member (31) is provided at the inner center of the lower shell (3), and the rotating mechanism (5) is provided inside the isolation member (31).

3. The oral mucosa extraction device for genetic testing according to claim 2, characterized in that: An air bag (32) is provided between the lower shell (3) and the isolation piece (31), and tooth pads (33) are provided on both sides of the air bag (32).

4. The oral mucosa extraction device for genetic testing according to claim 2, characterized in that: The rotating mechanism (5) comprises a rotating drum (51) and a supporting rod (52); The rotating drum (51) is movably disposed in the isolating member (31), and the rotating drum (51) is connected to the swab end (4) via a connecting rod (53); The support rod (52) is rotatably disposed in the rotating drum (51).

5. The oral mucosa extraction device for genetic testing according to claim 4, characterized in that: The pushing mechanism (6) includes two slide cylinders (61) and two pushing rods (62); The two slide cylinders (61) are provided through the top of the lower shell (3); A push rod (62) is movably provided in each slide cylinder (61), and the push rod (62) is connected to the support rod (52).

6. The oral mucosa extraction device for genetic testing according to claim 1, characterized in that: The upper shell (2) is externally threadedly connected to the outer shell (21), and two sets of the adjustment mechanisms (7) are provided between the upper shell (2) and the outer shell (21).

7. The oral mucosa extraction device for genetic testing according to claim 6, characterized in that: The adjustment mechanism (7) comprises a connecting rod (71), a limiting block (72) and a connecting rope (73); The connecting rod (71) movably passes through the upper shell (2); The limiting block (72) is connected to the top of the connecting rod (71), and the limiting block (72) is engaged with the top of the upper shell (2) and the outer shell (21); The connecting rope (73) is connected to the bottom of the connecting rod (71) and movably passes through the lower shell (3) to the center of the bottom.

8. The oral mucosa extraction device for genetic testing according to claim 7, characterized in that: The two connecting ropes (73) are both connected to an adjusting rod (74) at one end away from the connecting rod (71), and the adjusting rod (74) is connected to a swab end (4) at one end away from the connecting rope (73).

9. The oral mucosa extraction device for genetic testing according to claim 1, characterized in that: An arc-shaped tongue depressor (8) is provided at the bottom of the lower shell (3).

Images