Blood sampling device for animal medicine experiment

Abstract

The invention provides a blood sampling device for animal medicine experiments, and relates to the technical field of blood sampling equipment. The sampling table is of a cuboid box-shaped structure, and a rectangular built-in opening is formed in the middle of the upper end of the sampling table; a lifting frame is fixedly arranged in the middle of the rear end of the internally-hidden opening in a vertically-upward mode. A connecting column is vertically arranged on the lifting frame, a vertical clamping air cylinder is fixedly arranged at the upper end of the connecting column, and a sampling carrying table is fixedly connected to the lower end of the connecting column and located at the position of the hidden opening. According to the invention, through systematic innovative design, the whole process optimization of animal blood sampling is realized. Firstly, a'operation-pacifying 'dual-mode sampling system is created through the synergistic effect of the lifting type sampling platform deck and the light-proof inner cavity, the platform deck is lifted to a working position during sampling so as to facilitate accurate operation, and the platform deck is lowered to a closed darkroom after sampling.

Description

Technical Field

[0001] The present invention relates to the technical field of blood sampling equipment, in particular to a blood sampling device for animal medical experiments. Background Art

[0002] In animal medical experiments, blood sampling is a key step in assessing animal health, monitoring disease progression, and verifying drug efficacy. However, traditional sampling methods have many limitations: prolonged exposure of experimental animals (such as mice) to open environments can easily lead to strong stress responses, causing fluctuations in hormone levels and affecting the accuracy of test results. Manually securing animals is difficult to precisely control: excessive tightening can cause tissue damage, while excessive loosening can cause the animal to struggle, increasing operational risks. Furthermore, animal excrement is difficult to handle during sampling and can easily contaminate the experimental environment. Frequently handling animals for multiple sampling sessions can increase their physical and psychological burdens. Summary of the Invention

[0003] The present invention relates to a blood sampling device for animal medical experiments, which aims to solve the problem that existing sampling devices focus on single function optimization, lack comprehensive consideration of animal welfare, operational convenience and experimental efficiency, and are difficult to meet the needs of high-precision and high-repeatability experiments.

[0004] The present invention provides a blood sampling device for animal medical experiments, specifically comprising: a sampling platform; the sampling platform is a rectangular box-shaped structure, and a rectangular inner opening is opened in the middle of the upper end of the sampling platform; a lifting frame is fixed vertically upward in the middle of the rear end of the inner opening; a connecting column is vertically provided on the lifting frame, and a vertical clamping cylinder is fixed on the upper end of the connecting column, and a sampling platform is fixedly connected to the lower end of the connecting column, and the sampling platform is located at the inner opening; a downward pressing mechanism is provided on the clamping cylinder, and the downward pressing mechanism is used to fix the mouse to be blood drawn on the sampling platform; the lifting frame is used to drive the connecting column to move vertically, and the sampling platform passes through the inner opening and enters the inner cavity of the sampling platform during the downward movement; a control box is hung on the front side wall of the sampling platform; A concave placement groove is horizontally opened in the middle of the top plane of the sampling platform, and the placement groove is used to hold mice. A food trough is provided at one end of the placement groove, and the food trough is used to hold food boxes. A sewage trough is provided at the other end of the placement groove, and an excrement collection box is held in the sewage trough. A mesh plate is provided at the groove of the sewage trough above the excrement collection box.

[0005] Optionally, a detachable cleaning door is provided on the side wall of one end of the sampling platform; and enclosures are provided on the three side ring edges of the upper end of the sampling platform.

[0006] Optionally, a lifting motor is provided at the upper end of the lifting frame. A vertical screw rod is provided in the lifting frame. A connecting block is rotationally and threadedly connected to the screw rod. The lifting motor drives the screw rod to rotate. The rotation of the screw rod drives the connecting block to move vertically. The connecting block is fixedly connected to the connecting column. When the connecting column drives the sampling stage to be flush with the top of the sampling table, there is still a certain movable stroke for the connecting block to move upward in the lifting frame. When the connecting block continues to move upward, the sampling stage moves upward to be above the sampling table, which is used for the disassembly and installation of the excrement collection box and the mesh plate.

[0007] Optionally, the pressing mechanism includes a clamping connecting seat, a clamping base plate and a clamping sleeve. The lower end of the piston rod of the clamping cylinder is fixedly connected with a "C"-shaped clamping connecting seat. A clamping base plate is provided at the lower end of the clamping connecting seat. Two buffer rods are symmetrically and perpendicularly fixed on the clamping base plate. The buffer rods are vertically and slidably connected to the clamping connecting seat. A plug is provided at the upper end of the buffer rod. A buffer spring is sleeved on the buffer rod between the bottom of the clamping connecting seat and the clamping base plate. The buffer spring provides a downward thrust for the clamping base plate at all times. The lower end of the clamping base plate is fixedly connected with an inverted "U"-shaped clamping sleeve. Four clamping grooves for placing the four limbs of the mouse are provided on the clamping sleeve. One end of the clamping sleeve close to the food trough is the head placement end of the mouse. A blood sampling hole is provided at a position on the clamping sleeve close to the neck of the mouse.

[0008] Optionally, both ends of the food trough are L-shaped table grooves. The left and right ends of the food box are respectively provided with outwardly protruding supporting platforms. The supporting platforms are clamped at the table grooves. A finger edge is vertically provided at the top edge of the food box above the supporting platform. The finger edge is used for inserting a finger to take out the food box from the food trough. Mouse food is placed in the food box. The top of one end of the food box close to the placement groove is flush with the bottom of the placement groove. The other end of the food box is flush with the top plane of the sampling table.

[0009] Optionally, a diversion slope inclined outward and downward is provided at the inner edge of the sewage discharge groove. The excrement collection box is located in the sewage discharge groove at the lower end of the diversion slope. Side grooves are respectively provided in the left and right groove walls at both ends of the placement groove at the top of the sewage discharge groove. The mesh plate is slid inserted into the upper end of the sewage discharge groove from one end of the side groove. The upper end surface of the mesh plate is flush with the top plane of the sampling table. A grid-shaped filter screen is provided on the mesh plate above the diversion slope along the distribution direction of the diversion slope. A collection port is provided on the mesh plate at the inner end of the filter screen. The excrement collection box is below the collection port. A stop bar is provided at the edge of the inner end of the collection port. A horizontal stop bar is provided on the top plane.

[0010] Optionally, a hanging plate is provided vertically upward at the top of the outer end of the excrement collection box, and the hanging plate is embedded in the placement groove surface outside the sewage trough. The upper end surface of the hanging plate is flush with the placement groove surface. A locking rod is provided at the middle of the end of the hanging plate for vertical sliding. The upper end of the locking rod slides vertically through the end of the mesh plate. The lower end of the locking rod is provided with an end head, which is made of rubber. A tension spring is connected to the locking rod between the end head and the bottom of the hanging plate. The tension spring provides an upward pulling force for the locking rod. When the mesh plate and the excrement collection box need to be taken out, the locking rod is pulled down, and the mesh plate is unlocked and can be pulled out. After the mesh plate is completely pulled out, the excrement collection box is moved up and taken out.

[0011] Optionally, two sets of limb splints are respectively provided in the sampling platforms on both sides of the placement slot, and the limb splints are used to clamp the limbs of the mouse to be sampled for blood. The clamping sleeve is moved down to press the mouse's body and clamp it in cooperation with the limb splints, and the sampling needle is used to collect blood through the blood sampling hole. After one sampling, the lifting motor is controlled to work, the connecting column is moved down, and the sampling platform is moved down to the light-proof inner cavity of the sampling platform to soothe the mouse.

[0012] The present invention provides a blood sampling device for animal medical experiments, which has the following beneficial effects: This invention optimizes the entire animal blood sampling process through a systematic and innovative design. First, the synergistic effect of the lifting sampling platform and the light-proof inner cavity creates a dual-mode "operation-comfort" sampling system: during sampling, the platform rises to the working position for precise operation, and after sampling, the platform descends to a closed darkroom. The dark environment and continuous feeding significantly reduce the stress response of mice, allowing for multiple sampling without the need to transfer animals, ensuring experimental continuity while reducing interference with animals caused by human intervention.

[0013] Secondly, the clamping mechanism adopts an elastic fixing solution of buffer spring and inverted U-shaped clamping sleeve, which achieves gentle restraint through constant downward pressure, avoiding tissue damage caused by traditional rigid clamping. At the same time, the limb slots and limb splints form a dual fixation system to ensure that the animal is completely still during blood collection, significantly improving puncture safety and sampling success rate.

[0014] Furthermore, the integrated waste management system utilizes diversion slopes, filters, and a layered collection structure to achieve solid-liquid separation and targeted collection. Combined with a quick assembly and disassembly design, the cleaning process is streamlined to minutes, effectively reducing the risk of cross-contamination. Furthermore, the embedded design of the food container not only maintains the animal's normal physiological state but also distracts the animal through the act of eating, creating a "positive reinforcement" soothing mechanism to further alleviate tension.

[0015] Finally, the clever combination of modular structure and reserved maintenance schedules allows for consumable replacement and equipment cleaning without disassembling the main structure, while the centralized control box enables real-time monitoring of equipment status and one-click operation. In summary, this invention, drawing on the multi-dimensional perspectives of animal behavior, ergonomics, and experimental biology, has constructed an efficient, safe, and user-friendly sampling solution. This not only improves the reliability of experimental data, but also promotes the dual advancement of animal experimental ethics and operational standards. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings of the embodiments are briefly introduced below.

[0017] The drawings described below only relate to some embodiments of the present invention, but are not intended to limit the present invention.

[0018] In the attached figure: Figure 1 shows a schematic diagram of the first axial view of the present invention; Figure 2 shows a second axial structural schematic diagram of the present invention; Figure 3 It shows the axial structural schematic diagram of the state in which the sampling stage of the present invention is moved down into the sampling platform; Figure 4 It shows an axial structural schematic diagram of the lifting frame and the sampling platform of the present invention in a state of being separated; Figure 5 A schematic diagram of the lower axis structure of the clamping cylinder and the sampling stage of the present invention is shown; Figure 6 The present invention shows Figure 5 A in the middle is a schematic diagram of the structure of the enlarged part; Figure 7 It shows a schematic diagram of the axial structure of the sampling stage of the present invention in a partially disassembled state; Figure 8 The figure shows an axial structural diagram of the sampling platform and the excrement collection box of the present invention in a separated state.

[0019] List of reference numerals: 1. Sampling table; 11. Cleaning door; 12. Internal opening; 13. Enclosure; 2. Control box; 3. Lifting frame; 31. Lifting motor; 32. Connecting block; 4. Connecting columns; 5. Clamping cylinder; 51. Clamping seat; 52. Clamping base plate; 521. Buffer rod; 522. Buffer spring; 53. Clamping sleeve; 531. Clamping slot; 532. Blood sampling hole; 6. Sampling platform; 61. Placement trough; 611. Food trough; 612. Sewage trough; 613. Diversion slope; 614. Side trough; 62. Limb splint; 63. Food box; 631. Stretching platform; 632. Finger edge; 64. Excrement collection box; 641. Hanging plate; 642. Locking rod; 643. End; 644. Tension spring; 65. Mesh plate; 651. Filter screen; 652. Collection port; 653. Baffle. DETAILED DESCRIPTION

[0020] To make the purpose, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the described embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0021] Please refer to Figures 1 to 8 : Example 1: The present invention proposes a blood sampling device for animal medical experiments, comprising: a sampling platform 1; the sampling platform 1 is a rectangular box-shaped structure, and a rectangular inner opening 12 is opened in the middle of the upper end of the sampling platform 1; a lifting frame 3 is fixed vertically upward in the middle of the rear end of the inner opening 12; a connecting column 4 is vertically provided on the lifting frame 3, and a vertical clamping cylinder 5 is fixed on the upper end of the connecting column 4, and a sampling platform 6 is fixedly connected to the lower end of the connecting column 4, and the sampling platform 6 is located at the inner opening 12; a downward pressing mechanism is provided on the clamping cylinder 5, and the downward pressing mechanism is used to fix the mouse to be blood drawn on the sampling platform 6; the lifting frame 3 is used to drive the connecting column 4 to move vertically, and the sampling platform 6 passes through the inner opening 12 during the downward movement and enters the inner cavity of the sampling platform 1; a control box 2 is hung on the front side wall of the sampling platform 1; A concave placement groove 61 is horizontally opened in the middle of the top plane of the sampling platform 6. The placement groove 61 is used to hold mice. A food trough 611 is provided at one end of the placement groove 61. The food trough 611 is used to hold the food box 63. A sewage trough 612 is provided at the other end of the placement groove 61. An excrement collection box 64 is held in the sewage trough 612. A mesh plate 65 is provided at the notch of the sewage trough 612 above the excrement collection box 64.

[0022] A detachable cleaning door 11 is provided on one side wall of the sampling platform 1 ; and enclosures 13 are provided on three sides of the upper end of the sampling platform 1 .

[0023] Among them, a lifting motor 31 is provided at the upper end of the lifting frame 3. A lead screw is vertically arranged in the lifting frame 3. A connecting block 32 is rotationally and threadedly connected to the lead screw. The lifting motor 31 drives the lead screw to rotate. The rotation of the lead screw drives the connecting block 32 to move vertically. The connecting block 32 is fixedly connected to the connecting column 4. When the connecting column 4 drives the sampling stage 6 to be flush with the top of the sampling table 1, there is still a certain upward movement stroke of the connecting block 32 in the lifting frame 3. When the connecting block 32 continues to move upward, the sampling stage 6 moves upward to be above the sampling table 1, which is used for the disassembly and installation of the excrement collection box 64 and the mesh plate 65.

[0024] Among them, the pressing mechanism includes a clamping connecting seat 51, a clamping base plate 52 and a clamping sleeve 53. The lower end of the piston rod of the clamping cylinder 5 is fixedly connected with a "C"-shaped clamping connecting seat 51. A clamping base plate 52 is provided at the lower end of the clamping connecting seat 51. Two buffer rods 521 are symmetrically and perpendicularly fixed on the clamping base plate 52. The buffer rods 521 are vertically and slidably connected to the clamping connecting seat 51. A plug is provided at the upper end of the buffer rod 521. A buffer spring 522 is sleeved on the buffer rod 521 between the bottom of the clamping connecting seat 51 and the clamping base plate 52. The buffer spring 522 provides a downward thrust for the clamping base plate 52 all the time. The lower end of the clamping base plate 52 is fixedly connected with an inverted "U"-shaped clamping sleeve 53. Four clamping grooves 531 for clamping the four limbs of the mouse are provided on the clamping sleeve 53. One end of the clamping sleeve 53 close to the food trough 611 is the head placement end of the mouse. A blood collection hole 532 is provided at the position of the clamping sleeve 53 close to the mouse's neck.

[0025] Among them, both ends of the food trough 611 are L-shaped table grooves. The left and right ends of the food box 63 are respectively provided with outwardly protruding supporting platforms 631. The supporting platforms 631 are clamped at the table grooves. A finger edge 632 is vertically provided at the top edge of the food box 63 above the supporting platform 631. The finger edge 632 is used to insert a finger to take out the food box 63 from the food trough 611. Mouse food is placed in the food box 63. The top of one end of the food box 63 close to the placement groove 61 is flush with the bottom of the placement groove 61. The other end of the food box 63 is flush with the top plane of the sampling table 1.

[0026] Among them, a diversion slope 613 inclined outward and downward is provided at the inner edge of the sewage discharge groove 612. The excrement collection box 64 is located in the sewage discharge groove 612 at the lower end of the diversion slope 613. Side grooves 614 are respectively provided in the left and right end walls of the placement groove 61 at the top of the sewage discharge groove 612. The mesh plate 65 is slid inserted into the upper end of the sewage discharge groove 612 from one end of the side groove 614. The upper end surface of the mesh plate 65 is flush with the top plane of the sampling table 1. A grid-shaped filter screen 651 is provided on the mesh plate 65 above the diversion slope 613 along the distribution direction of the diversion slope 613. A collection port 652 is provided on the mesh plate 65 at the inner end of the filter screen 651. The excrement collection box 64 is located below the collection port 652. A stop strip 653 is provided at the inner edge of the collection port 652. A horizontal stop strip 653 is provided on the top plane.

[0027] Among them, a hanging plate 641 is vertically provided on the top of the outer end of the excrement collection box 64, and the hanging plate 641 is embedded in the groove surface of the placement groove 61 outside the sewage trough 612. The upper end surface of the hanging plate 641 is flush with the groove surface of the placement groove 61, and a locking rod 642 is vertically slidably provided in the middle of the end of the hanging plate 641. The upper end of the locking rod 642 slides vertically through the end of the mesh plate 65, and the lower end of the locking rod 642 is provided with an end head 643. The end head 643 is made of rubber, and a tension spring 644 is connected to the locking rod 642 between the end head 643 and the bottom of the hanging plate 641. The tension spring 644 provides the locking rod 642 with an upward pulling force. When the mesh plate 65 and the excrement collection box 64 need to be taken out, the locking rod 642 is pulled down, and the mesh plate 65 is unlocked and can be pulled out. After the mesh plate 65 is completely pulled out, the excrement collection box 64 is moved up and taken out.

[0028] Example 2. On the basis of Example 1, two groups of limb splints 62 are respectively provided in the sampling platforms 6 on both sides of the placement slot 61. The limb splints 62 are used to clamp the limbs of the mouse to be sampled for blood. The clamping sleeve 53 moves down to press the body of the mouse and cooperates with the limb splints 62 to clamp the mouse. The sampling needle tube draws blood through the blood sampling hole 532. After one sampling, the lifting motor 31 is controlled to work, the connecting column 4 moves down, and the sampling platform 6 moves down to the light-proof inner cavity of the sampling platform 1 to comfort the mouse.

[0029] The following further explains and illustrates the functions and effects of each structure in the above content to help those skilled in the art better understand the technical solution: The sampling platform 1 is a rectangular box-shaped base, and the inner opening 12 opened on its top is used to accommodate the lifting sampling platform 6. When the lifting frame 3 drives the screw to rotate through the lifting motor 31, the connecting block 32 drives the connecting column 4 and the sampling platform 6 to move vertically. In the sampling state, the sampling platform 6 moves to a state flush with the top plane of the sampling platform 1. After sampling is completed, the sampling platform 6 moves down to the light-proof inner cavity of the sampling platform 1, which can effectively reduce the stress response of the mice. When sampling again, the sampling platform 6 can be raised again to a state flush with the top plane of the sampling platform 1 for sampling. Sampling can be repeated multiple times to avoid the mice being exposed to the outside for a long time during sampling and causing emergency reactions. It can also reduce the fear emergency reaction of the experimenter and improve the effective progress of the experiment. When maintaining or replacing consumables, the connecting block 32 can continue to move upward to make the sampling platform 6 higher than the plane of the sampling platform 1, making it easier to operate the excrement collection box 64 and the mesh plate 65. The cleaning door 11 facilitates internal cleaning. The control box 2 is mounted at the front end to centrally control the operation of the equipment.

[0030] The placement slot 61 is embedded in the top of the sampling platform 6, and the food trough 611 and the sewage trough 612 at both ends carry the food box 63 and the excrement collection box 64 respectively. The clamping cylinder 5 drives the clamping seat 51 to press down, and through the elastic cooperation of the buffer rod 521 and the buffer spring 522, the clamping base plate 52 and the inverted U-shaped clamping sleeve 53 gently fix the mouse body with constant pressure. The four clamping slots 531 of the clamping sleeve 53 accurately restrain the mouse's limbs to prevent struggle; the blood collection hole 532 is opened at the neck to facilitate needle puncture. At the same time, the limb splints 62 on both sides of the placement slot 61 work together to fix the limbs, forming a multiple restraint system to ensure a stable and safe blood collection process.

[0031] The food box 63 is connected to the L-shaped table groove of the food trough 611 through the stretchers 631 at both ends, and the finger edge 632 on the top is convenient for picking up and replacing with fingers. The inner end of the food box 63 is flush with the bottom of the placement trough 61 to ensure that the mice can eat without obstacles. The setting of the food box 63 can further reduce the stress response of the mice, thereby facilitating the smooth progress of the experiment. A guide slope 613 is provided in the sewage trough 612, which cooperates with the filter screen 651 on the mesh plate 65 to achieve solid-liquid separation: the excrement flows to the collection port 652 through the guide slope 613, and the liquid flows into the excrement collection box 64 through the filter screen 651. The mesh plate 65 is slid into the side groove 614, and the top baffle 653 prevents the dirt from overflowing. The hanging plate 641 of the excrement collection box 64 is embedded in the groove surface, and the locking rod 642 automatically locks the mesh plate 65 under the action of the tension spring 644. Pulling down the locking rod 642 can unlock the mesh plate 65 and take out the excrement collection box 64 in sequence, simplifying the cleaning process.

[0032] After a single blood draw, the lift 3 lowers the sampling platform 6 into the enclosed cavity of the sampling station 1. The dark environment significantly reduces anxiety in the mice. The continuous supply of food from the food box 63 further distracts the mice, reducing physiological stress between experiments. All removable components (food box 63, mesh plate 65, and excrement collection box 64) utilize slide rails or snap-fit mechanisms. This, combined with the reserved operating space within the lift travel, allows for quick replacement without the need to transfer the animals, significantly improving experimental efficiency and animal welfare.

[0033] Working principle: At the start of the experiment, the operator activates the lifting motor 31 through the control box 2, driving the screw in the lifting frame 3 to rotate, which in turn drives the connecting block 32 and the connecting column 4 upward, raising the sampling platform 6 to a working position flush with the top plane of the sampling platform 1. At this point, the mouse is placed in the placement slot 61 of the sampling platform 6, with its head facing the feeding trough 611 and its limbs naturally resting on the bottom of the trough. The food box 63 is fixed by the two end platforms 631 that snap into the L-shaped table slot of the feeding trough 611. Its inner end is flush with the bottom of the placement slot 61, ensuring that the mouse can eat without obstruction. The sewage trough 612 is pre-installed with a mesh panel 65 (inserted through the side slot 614) and an excrement collection box 64 (the locking rod 642 automatically locks the mesh panel 65 under the action of the tension spring 644).

[0034] The clamping cylinder 5 is activated through the control box 2, and the piston rod pushes the clamping seat 51 downward. The clamping seat 51 drives the clamping base 52 and the inverted U-shaped clamping sleeve 53 to descend, and the buffer rod 521 slides along the clamping seat 51. The buffer spring 522 provides a constant downward force, so that the clamping sleeve 53 gently covers the mouse body. The mouse's limbs are precisely clamped into the four clamping slots 531 of the clamping sleeve 53 (in Example 2, the limb splints 62 on both sides of the placement slot 61 synchronously restrain the limbs), forming a multiple fixation. At this time, the mouse's neck is exposed under the blood sampling hole 532 of the clamping sleeve 53, and the operator punctures and draws blood through the blood sampling hole 532. The buffer mechanism prevents excessive pressure from injuring the animal and ensures safe operation.

[0035] After a single blood draw is completed, the lifting motor 31 is controlled to reverse, and the connecting column 4 drives the sampling platform 6 to move downward, and enters the light-proof inner cavity of the sampling platform 1 through the internal opening 12. The dark environment combined with the continuous food supply from the food box 63 significantly relieves the anxiety of the mice. During this period, the mouse excrement falls onto the mesh plate 65: the solids slide to the collection port 652 through the guide slope 613, and the liquid flows into the excrement collection box 64 through the filter 651. The barrier bar 653 prevents the dirt from overflowing. After the soothing is completed, the sampling platform 6 can be raised to the working position again for multiple sampling to avoid the stress caused by repeated capture.

[0036] When cleaning is required, control the lift motor 31 to raise the sampling platform 6 to the maintenance position, above the surface of the sampling platform 1 (the connecting block 32 moves upward using its reserved travel). Pull down the locking lever 642 of the excrement collection box 64 to unlock it. First, pull out the mesh plate 65, then lift the hanging plate 641 to remove the excrement collection box 64; the food box 63 is removed using the finger edge 632. After cleaning, reinstall the consumables and lower the sampling platform 6 back to the working or comforting position. Periodically open the cleaning door 11 to clean the interior of the sampling platform 1.

[0037] In this article, there are several points to note: 1. The drawings of the embodiments of the present invention only relate to the structures related to the embodiments of the present invention. Other structures may refer to conventional designs.

[0038] 2. In the absence of conflict, the embodiments of the present invention and the features therein may be combined with each other to form new embodiments.

[0039] The above are only specific embodiments of the present invention, but the scope of protection of the present invention is not limited thereto. Any technician familiar with this technical field can easily think of changes or replacements within the technical scope disclosed by the present invention, which should be covered by the scope of protection of the present invention.

Claims

1. A blood sampling device for animal medical experiments, comprising: A sampling platform (1); the sampling platform (1) is a rectangular box-shaped structure, and a rectangular inner opening (12) is provided in the middle of the upper end of the sampling platform (1); a lifting frame (3) is fixed vertically upward in the middle of the rear end of the inner opening (12); a connecting column (4) is vertically provided on the lifting frame (3), and a vertical clamping cylinder (5) is fixed on the upper end of the connecting column (4), and a sampling platform (6) is fixedly connected to the lower end of the connecting column (4), and the sampling platform (6) is located at the inner opening (12); it is characterized in that a downward pressing mechanism is provided on the clamping cylinder (5), and the downward pressing mechanism is used to fix the mouse to be blood drawn on the sampling platform (6); the lifting frame (3) is used to drive the connecting column (4) to move vertically, and the sampling platform (6) passes through the inner opening (12) during the downward movement and enters the inner cavity of the sampling platform (1); a control box (2) is hung on the front side wall of the sampling platform (1); A concave placement groove (61) is horizontally provided in the middle of the top plane of the sampling platform (6), and the placement groove (61) is used to hold mice. A food trough (611) is provided at one end of the placement groove (61), and the food trough (611) is used to hold a food box (63). A sewage trough (612) is provided at the other end of the placement groove (61), and an excrement collection box (64) is held in the sewage trough (612). A mesh plate (65) is provided at the notch of the sewage trough (612) above the excrement collection box (64).

2. The blood sampling device for animal medical experiments according to claim 1, characterized in that: A detachable cleaning door (11) is provided on a side wall at one end of the sampling platform (1); and enclosures (13) are respectively provided on three side ring edges of the upper end of the sampling platform (1).

3. The blood sampling device for animal medical experiments according to claim 1, characterized in that: The upper end of the lifting frame (3) is provided with a lifting motor (31), and a screw rod is vertically provided in the lifting frame (3). A screw-connected connecting block (32) is rotated on the screw rod. The lifting motor (31) drives the screw rod to rotate, and the rotation of the screw rod drives the connecting block (32) to move vertically. The connecting block (32) is fixedly connected to the connecting column (4). When the connecting column (4) drives the sampling platform (6) to be flush with the top of the sampling platform (1), the connecting block (32) still has a movable stroke upward on the lifting frame (3). The connecting block (32) continues to move upward, and the sampling platform (6) moves upward and is above the sampling platform (1), which is used for disassembly and installation of the excrement collection box (64) and the mesh plate (65).

4. The blood sampling device for animal medical experiments according to claim 3, characterized in that: The pressing mechanism includes a clamping connecting seat (51), a clamping base plate (52) and a clamping sleeve (53). The lower end of the piston rod of the clamping cylinder (5) is fixedly connected to a "C"-shaped clamping connecting seat (51). The lower end of the clamping connecting seat (51) is provided with a clamping base plate (52). Two buffer rods (521) are symmetrically and perpendicularly fixed on the clamping base plate (52). The buffer rods (521) are vertically and slidably connected to the clamping connecting seat (51). The upper ends of the buffer rods (521) are provided with plugs. A buffer spring (522) is sleeved on the buffer rods (521) between the bottom of the clamping connecting seat (51) and the clamping base plate (52). The buffer spring (522) provides a downward thrust for the clamping base plate (52) all the time. The lower end of the clamping base plate (52) is fixedly connected to an inverted "U"-shaped clamping sleeve (53). Four clamping grooves (531) for placing the four limbs of the mouse are formed on the clamping sleeve (53). One end of the clamping sleeve (53) close to the food trough (611) is the head placement end of the mouse. A blood sampling hole (532) is formed at a position on the clamping sleeve (53) close to the mouse's neck.

5. The blood sampling device for animal medical experiments according to claim 1, characterized in that: Both ends of the food trough (611) are L-shaped table grooves. The left and right ends of the food box (63) are respectively provided with outwardly protruding supporting platforms (631). The supporting platforms (631) are clamped at the table grooves. A finger edge (632) is vertically provided at the top edge of the food box (63) above the supporting platform (631). The finger edge (632) is used to insert a finger to take out the food box (63) from the food trough (611). Mouse food is placed in the food box (63). The top of one end of the food box (63) close to the placement groove (61) is flush with the bottom of the placement groove (61). The other end of the food box (63) is flush with the top plane of the sampling table (1).

6. The blood sampling device for animal medical experiments according to claim 1, characterized in that: An inclined downward导流坡 (613) is provided at the inner edge of the sewage discharge groove (612). The excrement collection box (64) is located in the sewage discharge groove (612) at the lower end of the导流坡 (613). Side grooves (614) are respectively formed in the left and right end walls of the placement groove (61) at the top of the sewage discharge groove (612). The mesh plate (65) is slidably inserted into the upper end of the sewage discharge groove (612) from one end of the side groove (614). The upper end surface of the mesh plate (65) is flush with the top plane of the sampling table (1). A grid-shaped filter screen (651) is provided on the mesh plate (65) above the导流坡 (613) along the distribution direction of the导流坡 (613). A collection port (652) is formed on the mesh plate (65) at the inner end of the filter screen (6). The excrement collection box (64) is located below the collection port (652). A stop bar (653) is provided at the inner edge of the collection port (652). A horizontal stop bar (653) is provided on the top plane. It should be noted that the "导流坡" in the original text seems to be a misspelling. I translated it as "导流坡" according to what was provided. You may need to check and correct it if it's incorrect. Also, the repeated "65)" in the description of the "收集口 (652)" in the third paragraph might be a mistake in the original text.

7. The blood sampling device for animal medical experiments according to claim 6, characterized in that: The top of the outer end of the excrement collection box (64) is provided with a hanging plate (641) vertically upward, and the hanging plate (641) is embedded in the groove surface of the placement groove (61) outside the sewage trough (612). The upper end surface of the hanging plate (641) is flush with the groove surface of the placement groove (61). The middle part of the end of the hanging plate (641) is provided with a locking rod (642) that slides vertically. The upper end of the locking rod (642) slides vertically through the end of the mesh plate (65). The lower end of the locking rod (642) is provided with an end head (641). 43), the end (643) is made of rubber, and a tension spring (644) is connected to the locking rod (642) between the end (643) and the bottom of the hanging plate (641). The tension spring (644) provides an upward pulling force for the locking rod (642). When the mesh plate (65) and the excrement collection box (64) need to be taken out, the locking rod (642) is pulled down, and the mesh plate (65) is released from the locked state and can be pulled out. After the mesh plate (65) is completely pulled out, the excrement collection box (64) is moved up and taken out.

8. The blood sampling device for animal medical experiments according to claim 4, characterized in that: Two sets of limb splints (62) are respectively provided in the sampling platform (6) on both sides of the placement groove (61). The limb splints (62) are used to clamp the limbs of the mouse to be blood sampled. The clamping sleeve (53) moves down to press the mouse's body and clamp it with the limb splints (62). The sampling needle is used to collect blood through the blood sampling hole (532). After one sampling, the lifting motor (31) is controlled to work, the connecting column (4) moves down, and the sampling platform (6) moves down to the inner cavity of the light-proof sampling platform (1) to comfort the mouse.

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