Aortic stent and method of manufacturing the same

Abstract

The application relates to an aortic stent and a manufacturing method thereof. The manufacturing method of the aortic stent comprises the following steps: providing a proximal stent section for being implanted into a descending aorta, a distal stent section for being implanted into an ascending aorta, and an arch stent section for being implanted into an aortic arch; providing a foldable covering film; covering the covering film on the proximal stent section and the distal stent section; providing a keel line with a pre-bent shape; and penetrating the keel line through the proximal stent section, the arch stent section and the distal stent section; wherein the proximal stent section, the arch stent section and the distal stent section jointly define a supporting cavity, the covering film is foldable, and the keel line has the pre-bent shape. The whole stent can be bent along the bending direction of the keel line, so that the elastic straightening force of the aortic stent itself can be reduced, the flexibility of the aortic stent is improved, and the complications caused by poor adhesion are reduced.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to aortic stents and methods for manufacturing the same. Background Technology

[0002] Aortic stents are commonly used medical devices in minimally invasive interventional procedures. They function to isolate the false lumen to prevent vascular rupture and reshape the true lumen to restore blood supply to distal vessels.

[0003] However, due to the complex and varied vascular anatomy, higher requirements are placed on the wall apposition performance and flexibility of aortic stents. Therefore, how to reduce the elastic recoil force inherent in the aortic stent structure itself, improve the flexibility of aortic stents, and reduce complications caused by poor wall apposition has become an urgent problem to be solved. Summary of the Invention

[0004] Therefore, it is necessary to provide an aortic stent and its manufacturing method to address the above technical problems, which can reduce the elastic recoil force inherent in the aortic stent structure itself, improve the flexibility of the aortic stent, and reduce complications caused by poor wall apposition.

[0005] According to a first aspect of this application, a method for manufacturing an aortic stent is provided, comprising:

[0006] Provided a proximal stent segment for implantation in the descending aorta, a distal stent segment for implantation in the ascending aorta, and an arch stent segment for implantation in the aortic arch; wherein the arch stent segment is located between the proximal stent segment and the distal stent segment, and is connected to the proximal stent segment and the distal stent segment respectively.

[0007] Provides a foldable coating;

[0008] The covering film is applied to the proximal stent segment and the distal stent segment;

[0009] Provide keel wire with a pre-curved shape; and

[0010] The keel line passes through the proximal support, the arch support, and the distal support;

[0011] The proximal stent segment, the arch stent segment, and the distal stent segment together define a support cavity.

[0012] In one embodiment, providing a foldable covering film specifically includes:

[0013] Provide initial coating materials;

[0014] The initial coating material is sandwiched between a first mold with an external textured structure and a second mold with an internal textured structure;

[0015] The initial coating material is hot-pressed using the first mold and the second mold to obtain the coating;

[0016] Wherein, the outer texture structure is adapted to the inner texture structure;

[0017] The second mold includes a first mold column, and the internal texture structure includes a plurality of arc-shaped protrusions spaced apart on the inner peripheral wall of the first mold column along the axial direction of the first mold column.

[0018] In one embodiment, the hot pressing process parameters for hot pressing the initial coating material using the first mold and the second mold include: hot pressing temperature of 60℃-80℃; and hot pressing time of 10s-20s.

[0019] In one embodiment, providing the keel wire with a pre-bent shape specifically includes:

[0020] Provide initial keel materials;

[0021] The initial keel material is placed in a shaping mold to form the keel line with a pre-bent shape;

[0022] The shaping mold has a curved groove adapted to the keel line.

[0023] In one embodiment, the initial keel material is placed in a shaping mold, and the shaping process parameters include: shaping temperature of 480℃-520℃; shaping time of 10min-15min.

[0024] According to a second aspect of this application, an aortic stent is provided, comprising:

[0025] The proximal stent segment is used for implantation within the descending aorta;

[0026] The distal stent segment is used for implantation within the ascending aorta;

[0027] An aortic arch stent segment for implantation within the aortic arch; the aortic arch stent segment is located between the proximal stent segment and the distal stent segment, and is connected to both the proximal and distal stent segments respectively; and

[0028] A film is applied to the proximal stent segment and the distal stent segment; and

[0029] The keel line has a pre-bent shape and the keel line runs through the proximal support section, the bow support section and the distal support section;

[0030] The proximal stent segment, the arch stent segment, and the distal stent segment together define a support cavity;

[0031] The covering is foldable, so that the portion of the covering applied to the proximal stent segment can be folded along the bending direction of the proximal stent segment, and the portion of the covering applied to the distal stent segment can be folded along the bending direction of the distal stent segment.

[0032] In one embodiment, the arch support segment is provided with a plurality of first holes communicating with the support cavity, the first holes being used to communicate with branch vessels on the aortic arch;

[0033] Along the radial direction of the supporting cavity, the arched stent segment has a branch vessel side and a first side disposed opposite to each other;

[0034] All the first holes are located on the branch vessel side of the arched stent segment;

[0035] The first side of the bow support section is provided with a plurality of second holes communicating with the support cavity;

[0036] The diameter of the second hole is smaller than the diameter of the first hole.

[0037] In one embodiment, the bow support segment is constructed as a mesh structure having multiple nodes;

[0038] Within a predetermined area on the branch vessel side of the arched stent segment, the number of nodes in the mesh structure is a first number;

[0039] Within the preset area region on the first side of the bow support section, the number of nodes in the grid structure is a second number;

[0040] Wherein, the first quantity is less than the second quantity.

[0041] In one embodiment, the aortic stent further includes an indicator on the proximal stent segment or the distal stent segment;

[0042] The indicator is used to indicate the direction of the proximal stent segment relative to the distal stent segment in the extension direction parallel to the proximal stent segment, and to indicate the direction of the branch vessel side relative to the first side in the radial direction of the support lumen.

[0043] In one embodiment, the aortic stent has a first cross-section extending along the axial direction of the support lumen; the end of the keel line near the proximal stent segment and the end of the keel line near the distal stent segment are located on the same side of the first cross-section; or, the end of the keel line near the proximal stent segment and the end of the keel line near the distal stent segment are located on opposite sides of the first cross-section.

[0044] In the technical solution of this application, the covering is foldable, so that the portion of the covering applied to the proximal stent segment can be folded along the extension direction of the proximal stent segment, and the portion of the covering applied to the distal stent segment can also be folded along the extension direction of the distal stent segment. That is, the first covering portion can extend and retract along the extension direction of the proximal stent segment, and the second covering portion can extend and retract along the extension direction of the distal stent segment. Given that the distal stent segment is implanted into the ascending aorta, and the ascending aorta has a relatively arranged lateral curvature and a medial curvature with a greater degree of curvature than the lateral curvature, the elastic second covering portion is stretched more on the side closer to the lateral curvature, and less stretched or not stretched at all on the side closer to the medial curvature. In other words, the length of the second covering portion closer to the lateral curvature can be greater than the length of the second covering portion closer to the medial curvature. This allows the portion of the endothelial graft covering the distal stent segment (i.e., the second endothelial graft) to expand and contract according to the curvature of the ascending aorta; similarly, the portion of the endothelial graft covering the proximal stent segment (i.e., the first endothelial graft) can expand and contract according to the length of the descending aorta. This results in better compliant stress on the aortic stent. In addition, the keel line has a certain curvature, allowing the entire stent to bend in accordance with the direction of the keel line. This reduces the elastic recoil force inherent in the aortic stent itself, improves the flexibility of the aortic stent, and reduces complications caused by poor apposition. Attached Figure Description

[0045] Figure 1 A schematic diagram of the structure of an aortic stent according to an embodiment of this application is shown.

[0046] Figure 2 A schematic diagram of an aortic stent implanted in the aorta according to an embodiment of this application is shown.

[0047] Figure 3 A schematic diagram of the branch vessel side of the arch stent segment according to an embodiment of this application is shown.

[0048] Figure 4 A schematic diagram of the structure of the first side of the bow support segment according to an embodiment of this application is shown.

[0049] Figure 5 A schematic diagram of the structure of the indicator and the distal stent segment according to an embodiment of this application is shown.

[0050] Figure 6 A schematic diagram of the structure of the indicator, keel line, bow support segment and distal support segment according to an embodiment of this application is shown.

[0051] Figure 7 A schematic diagram of the structure of the indicator, keel line, bow support segment and distal support segment of another embodiment of this application is shown.

[0052] Figure 8 A schematic diagram of the initial coating material according to an embodiment of this application is shown.

[0053] Figure 9 A schematic diagram of a first mold and a second mold according to an embodiment of this application is shown.

[0054] Figure 10 A schematic diagram of the hot-pressed coating according to an embodiment of this application is shown.

[0055] Figure 11 A schematic diagram of the structure of an aortic stent according to an embodiment of this application is shown.

[0056] Figure 12 A schematic diagram of the structure of a molding die according to an embodiment of this application is shown.

[0057] Reference numerals: 10, aortic stent; 100, proximal stent segment; 200, distal stent segment; 300, arched stent segment; 301, branch vessel side; 302, first side; 303, node portion; 304, non-node portion; 310, first support wire; 311, first bend portion; 312, second bend portion; a, first region; 400, covering; 410, first covering portion; 420, second covering portion; 430, arcuate protrusion; 440, annular recess; 4001, initial covering material; Q, support lumen; K1, first hole; K2, second hole; 500, indicator; 600, Keel line; 210, Second support wire; 211, Third bend; 212, Head; 213, Tail; 110, Third support wire; 111, Fourth bend; 21, Descending aorta; 22, Ascending aorta; 221, Outer bend; 222, Inner bend; 23, Aortic arch; 24, Branch vessels; 71, First mold; 711, Outer texture structure; 72, Second mold; 721, Inner texture structure; 7211, Arc-shaped protrusion; 722, First mold column; 7201, First sub-mold; 7202, Second sub-mold; 80, Shaping mold; 801, Bending groove. Detailed Implementation

[0058] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0059] In the description of this application, it should be understood that if terms such as "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0060] Furthermore, where the terms "first" and "second" appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, where the term "multiple" appears, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0061] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0062] In this application, unless otherwise expressly specified and limited, the use of descriptions such as "above" or "below" the second feature indicates that the first and second features are in direct contact or indirect contact via an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0063] It should be noted that if an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. If so, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used in this application are for illustrative purposes only and do not represent the only possible implementation.

[0064] Figure 1 A schematic diagram of the structure of an aortic stent 10 according to an embodiment of this application is shown. Figure 2 A schematic diagram of an aortic stent 10 implanted in the aorta according to an embodiment of this application is shown.

[0065] Please refer to the following: Figure 1 and Figure 2 One embodiment of this application provides an aortic stent 10, including a proximal stent segment 100, a distal stent segment 200, an arch stent segment 300, a clasp 400, and a keel 600.

[0066] The proximal stent segment 100 is implanted in the descending aorta 21, the distal stent segment 200 is implanted in the ascending aorta 22, and the aortic arch stent segment 300 is implanted in the aortic arch 23.

[0067] The arched stent segment 300 is located between the proximal stent segment 100 and the distal stent segment 200, and is connected to both the proximal stent segment 100 and the distal stent segment 200, respectively. The arched stent segment 300 may be indirectly connected to the proximal stent segment 100 and the distal stent segment 200, or it may be directly connected to them; no specific limitation is made here.

[0068] The membrane 400 is applied to the proximal stent segment 100 and the distal stent segment 200.

[0069] The proximal stent segment 100, the arch stent segment 300, and the distal stent segment 200 together define a support cavity Q. The arch stent segment 300 is provided with a plurality of first holes K1 that communicate with the support cavity Q. The first holes K1 are used to communicate with the branch vessels 24 on the aortic arch 23.

[0070] Since the cladding 400 is applied to the proximal stent segment 100 and the distal stent segment 200, it can be understood that the arch stent segment 300 is the exposed segment of the aortic stent 10 that is implanted into the aortic arch 23. Combined with the first hole K1 on the arch stent segment 300, it can be connected to the supporting lumen Q and the branch vessels 24 on the aortic arch 23, respectively. In this way, the blood supply to the branch vessels 24 can be satisfied, while eliminating the need for drilling or fenestration, reducing the operation time and the risk of stroke in patients, and also reducing the difficulty of implanting the aortic stent 10.

[0071] The film 400 is foldable so that the portion of the film 400 covering the proximal stent segment 100 can be folded along the bending direction of the proximal stent segment 100, and the portion of the film 400 covering the distal stent segment 200 can be folded along the bending direction of the distal stent segment 200.

[0072] It is understood that the membrane 400 has elasticity or a certain degree of stretchability, so that the portion of the membrane 400 covering the proximal stent segment 100 can be stretched and extended along the bending direction of the proximal stent segment 100, and the portion of the membrane 400 covering the distal stent segment 200 can be stretched and extended along the bending direction of the distal stent segment 200.

[0073] In other words, the first covering portion 410 can be folded along the curvature of the proximal stent segment 100, and the second covering portion 420 can be folded along the curvature of the distal stent segment 200. Combined with the distal stent segment 200, it is implanted into the ascending aorta 22. The ascending aorta 22 has an outwardly curved side 221 and an inwardly curved side 222 with a greater degree of curvature than the outwardly curved side 221. Therefore, the elastic second covering portion 420 is stretched more on the side closer to the outwardly curved side 221, and less stretched or even unstretched on the side closer to the inwardly curved side 222. The length can be greater than the length of the second covering portion 420 near the inner curvature side 222, so that the portion of the covering portion 400 covering the distal stent segment 200 (i.e., the second covering portion 420) can be adjusted to accommodate different curvatures on the inner and outer sides of the ascending aorta 22. Similarly, the portion of the covering portion 400 covering the proximal stent segment 100 (i.e., the first covering portion 410) can be adjusted to accommodate different curvatures on the descending aorta 21. This allows the aortic stent 10 to have better compliance, effectively reducing the elastic recoil force of the aortic stent 10, thereby improving the flexibility of the aortic stent 10.

[0074] Optionally, the portion of the membrane 400 covering the proximal stent segment 100 and the portion of the membrane 400 covering the distal stent segment 200 are both cylindrical, and both include arcuate protrusions 430 alternately arranged along the extension direction of the membrane 400 and annular recesses 440 recessed in the radial direction of the arcuate protrusions 430 relative to the arcuate protrusions 430, with the annular recesses 440 formed between two adjacent arcuate protrusions 430.

[0075] It can be understood that two adjacent arc-shaped protrusions 430 and an annular recess 440 located between the two arc-shaped protrusions 430 define a first annular groove.

[0076] Thus, the alternating arrangement of the arc-shaped protrusions 430 and the annular recesses 440 creates a roughly wavy drape on the resulting covering 400. This allows the covering 400 to extend and retract along its extension direction. This is beneficial for the portion of the covering 400 covering the proximal stent segment 100 to extend and retract along the extension direction of the proximal stent segment 100, and also for the portion covering the distal stent segment 200 to extend and retract along the extension direction of the distal stent segment 200. Consequently, the aortic stent 10 exhibits better compliance, effectively reducing the elastic recoil force of the aortic stent 10 and thus improving its flexibility. Optionally, the first hole K1 of the arch stent segment 300 is used to connect to the three branch vessels 24 on the aortic arch 23, meaning that the arch stent segment 300 is positioned along the path of the three branch vessels 24 to ensure the blood supply needs of the three branch vessels 24.

[0077] The keel line 600 has a pre-bent shape and passes through the proximal support section 100, the arch support section 300 and the distal support section 200. Thus, the keel line 600 has a certain bending shape, which allows the entire support to bend in the direction of the bending of the keel line 600.

[0078] In addition, the bow support section 300 is a bare support section and uses a small ring weaving method, which also enables the entire support to have a good bending effect.

[0079] In some embodiments, please refer to Figure 1 , Figure 3 and Figure 4 Along the radial direction of the support cavity Q, the arch stent section 300 has a branch vessel side 301 and a first side 302 arranged opposite to each other. All first holes K1 are provided on the branch vessel side 301 of the arch stent section 300. The first side 302 of the arch stent section 300 is provided with a plurality of second holes K2 communicating with the support cavity Q. The diameter of the second hole K2 is smaller than the diameter of the first hole K1.

[0080] The branch vessel side 301 of the arch stent segment 300 refers to the side of the arch stent segment 300 that is close to the branch vessel 24 along the radial direction of the support lumen Q when the arch stent segment 300 is implanted in the aortic arch 23.

[0081] The first side 302 of the arch stent segment 300 refers to the side of the arch stent segment 300 away from the branch vessel 24 along the radial direction of the support lumen Q when the arch stent segment 300 is implanted in the aortic arch 23.

[0082] Since the diameter of the second hole K2 on the first side 302 of the arch stent segment 300 is smaller than that of the first hole K1, the diameter of the first hole K1 on the branch vessel side 301 of the arch stent segment 300 is larger. The first hole K1 adopts a large mesh design, which is less likely to interfere with blood flow. The larger diameter of the first hole K1 is also convenient for use in cases where a branch stent is implanted in the branch vessel 24, which is conducive to the reconstruction of the branch stent. Furthermore, it can effectively avoid local stenosis at the connection between the arch stent segment 300 and the branch vessel 24 when the branch stent is reconstructed.

[0083] In some embodiments, the arch stent segment 300 is constructed as a mesh structure having a plurality of nodes 303. Within a predetermined area region on the branch vessel side 301 of the arch stent segment 300, the number of nodes 303 in the mesh structure is a first number, and within a predetermined area region on the first side 302 of the arch stent segment 300, the number of nodes 303 in the mesh structure is a second number. The first number is less than the second number.

[0084] On the one hand, the number of nodes 303 in the branch vessel side 301 of the arch stent segment 300 is relatively small, and the probability of node 303 puncturing is low, which is beneficial for protecting the vessel. Furthermore, the diameter of the first hole K1 is relatively large, meaning the branch vessel side 301 of the arch stent segment 300 adopts a large mesh design, which is less likely to interfere with blood flow and facilitates branch stent reconstruction. Moreover, during branch stent reconstruction, it can effectively prevent local stenosis at the connection between the arch stent segment 300 and the branch vessel 24.

[0085] On the other hand, on the first side 302 of the arch stent segment 300, there are more nodes 303 of the mesh structure, which means that the first side 302 of the arch stent segment 300 has more joints, making the first side 302 of the arch stent segment 300 more flexible than the branch vessel side 301, thereby allowing the flexibility of the arch stent segment 300 to better conform to the structure of the aortic arch 23.

[0086] Specifically, the first side 302 of the bow support section 300 can achieve a bending effect of 0 to 270°. For example, the first side 302 of the bow support section 300 can achieve a bending effect of at least 180°, or even a bending effect of 270°.

[0087] Furthermore, since the first side 302 of the arch stent segment 300 is more flexible than the branch vessel side 301, the arch stent segment 300 is more likely to deform with the degree of curvature of the aortic arch 23 when implanted in the aortic arch 23. This makes it less likely for the arch stent segment 300 to generate elastic recoil force, resulting in a smaller force exerted by the aortic stent 10 on the blood vessel. This is beneficial for protecting the blood vessel and reducing the risk of damage to the ascending aorta 22 caused by the elastic recoil force generated by the aortic stent 10 after implantation.

[0088] Specifically, the first side 302 of the arch stent segment 300 adopts a single-ring cross-open loop braided structure, which increases the number of nodes 303 on the first side 302 of the arch stent segment 300 and has a shorter pitch, achieving a bending effect of 0~270°. This braiding method makes the arch stent segment 300 easy to bend, thus making it less prone to elastic recoil force. This results in a smaller force exerted by the aortic stent 10 on the blood vessel, which helps protect the blood vessel and reduces the risk of damage to the ascending aorta 22 caused by the elastic recoil force generated by the aortic stent 10 after implantation.

[0089] In addition, the first side 302 of the arch stent segment 300 adopts a single-ring cross-open loop braided structure, which allows the arch stent segment 300 to achieve better three-dimensional torsion in the blood vessel, thereby better conforming to the structure of the aortic arch 23 and reducing the risk of damage to the ascending aorta 22.

[0090] In some embodiments, the mesh structure includes a plurality of first support wires 310, each first support wire 310 having a plurality of first bends 311 and a plurality of second bends 312 alternately arranged circumferentially along the support cavity Q; the bending directions of the first bends 311 and adjacent second bends 312 are opposite, and they are spaced apart along the extension direction of the bow support segment 300. In two adjacent first support wires 310, the first bend 311 of one first support wire 310 and the second bend 312 of the other first support wire 310 are hooked together to form a node 303.

[0091] It is understandable that in two adjacent first support wires 310, the first bend 311 and the adjacent second bend 312 are hooked together to form a node 303.

[0092] The fact that the bending directions of the first bending portion 311 and the adjacent second bending portion 312 are opposite means that the first bending portion 311 and the adjacent second bending portion 312 protrude in opposite directions.

[0093] The first bend 311 and the adjacent second bend 312 are hooked together. Given that the diameter of the second hole K2 is smaller than that of the first hole K1, it can be understood that the first bend 311 and the adjacent second bend 312 have a certain amount of room to move between them. In this way, the arch support segment 300 can be easily bent and deformed to better conform to the structure of the aortic arch 23 and reduce the risk of damage to the ascending aorta 22.

[0094] In some embodiments, the aortic arch segment 300 has a first region a located on the branch vessel side 301 and a second region b located on the first side 302. The first region a is configured to face the communication port on the branch vessel 24 that connects to the aortic arch 23. Within the first region a, the maximum distance between two adjacent node portions 303 along the extension direction of the same first support wire 310 is a first distance. Within the second region b, the maximum distance between two adjacent node portions 303 along the extension direction of the same first support wire 310 is a second distance. The first distance is greater than the second distance.

[0095] Because the first spacing is greater than the second spacing, the first side 302 of the arch stent segment 300 has a shorter pitch, which is equivalent to the first side 302 of the arch stent segment 300 having more joints. This makes the first side 302 of the arch stent segment 300 more flexible than the branch vessel side 301, reducing the risk of damage to the ascending aorta 22 caused by the elastic recoil force generated by the aortic stent 10 after implantation. In addition, the branch vessel side 301 of the arch stent segment 300 has a longer pitch, which can reduce the number of nodes 303 of the branch vessel side 301 in the unit area of ​​the arch stent segment 300, and also reduce the accumulation of nodes, thereby reducing the possibility of vascular damage caused by node accumulation.

[0096] Specifically, the branch vessel side 301 of the arch stent segment 300 adopts a multi-ring perforation braid structure to reduce the number of opening segments of the branch vessel side 301 of the arch stent segment 300, thereby reducing the risk of damage to the aortic arch 23 by the branch vessel side 301 of the arch stent segment 300.

[0097] In some embodiments, the arch stent segment 300 has a first region a located on the branch vessel side 301. The first region a is disposed toward the communication port on the branch vessel 24 that connects to the aortic arch 23. In the first region a, at least one non-node portion 304 is provided between two adjacent node portions 303. The non-node portion 304 is the part where two adjacent first support wires 310 intersect each other on the orthographic projection on the target plane, and is the part where the two adjacent first support wires 310 are not connected to each other. The target plane is perpendicular to the direction from the branch vessel side 301 to the first side 302.

[0098] Since at least one non-node portion 304 is provided between two adjacent node portions 303 in the first region a, the number of node portions 303 on the branch vessel side 301 of the arch stent segment 300 within the preset area can be reduced, thereby making the probability of node portions 303 puncturing on the branch vessel side 301 of the arch stent segment 300 lower, which is beneficial to protect the blood vessel. In addition, at the non-node portion 304, the two adjacent first support wires 310 are not connected to each other, which is beneficial to enlarging the aperture of the first hole K1 on the branch vessel side 301 of the arch stent segment 300. The aperture of the first hole K1 can be 2-4 times the aperture of the second hole K2. In this way, the larger aperture of the first hole K1 is less likely to interfere with blood flow and is conducive to branch stent reconstruction. When reconstructing the branch stent, it can effectively avoid local stenosis at the connection between the arch stent segment 300 and the branch vessel 24.

[0099] In some embodiments, on the first side 302 of the bow support section 300, a plurality of first support wires 310 are arranged along the extension direction of the bow support section 300.

[0100] This facilitates the formation of a single-ring cross-open loop braided structure on the first side 302 of the bow support section 300.

[0101] In some embodiments, such as Figure 5 As shown, the aortic stent 10 also includes an indicator 500 disposed on the proximal stent segment 100 or the distal stent segment 200. The indicator 500 is used to indicate the direction of the proximal stent segment 100 relative to the distal stent segment 200 in the extension direction parallel to the proximal stent segment 100, and to indicate the direction of the branch vessel side 301 relative to the first side 302 in the radial direction of the support lumen Q.

[0102] The indicator 500 can be located on the proximal stent segment 100 or the distal stent segment 200. For example, the indicator 500 is located on the distal stent segment 200, extending along the extension direction of the covering film 400 on the distal stent segment 200, and one end of the indicator 500 is bent along the extension direction of the covering film 400 on the distal stent segment 200, thus the indicator 500 has a single-sided, single-bend design. For example, the indicator 500 can be shaped like a lowercase letter 'q' or an uppercase letter 'L'.

[0103] In this way, the indicator 500 can be observed using fluoroscopic equipment, and it can be determined whether the aortic stent 10 is implanted in the direction from the descending aorta 21 to the ascending aorta 22 along the direction from the proximal stent segment 100 to the distal stent segment 200 during the implantation process (if the orientation of the aortic stent 10 is incorrect based on the observed indicator 500, it can be corrected). It can also be determined whether the aortic stent 10 is set up with the branch vessel side 301 closer to the branch vessel 24 than the first side 302 during the implantation process, and whether the branch vessel side 301 can be set around the first side 302, so that the branch vessel side 301 is equivalent to the greater curvature side on the outside, and the first side 302 is equivalent to the lesser curvature side on the inside. This can improve the alignment accuracy of the aortic stent 10 during the implantation process and prevent vascular damage caused by poor stent morphology.

[0104] Optionally, if the aortic stent 10 is correctly aligned, the indicator 500 is positioned closer to the branch vessel side 301 in the radial direction of the support lumen Q than to the first side 302, and the indicator 500 is positioned approximately in the center.

[0105] In some embodiments, in conjunction with reference Figure 6 and Figure 7 The aortic stent 10 also includes a keel line 600, which is connected to the proximal stent segment 100, the arch stent segment 300, and the distal stent segment 200, respectively. The aortic stent 10 has a first cross-section extending along the axis of the support lumen Q. The ends of the keel line 600 near the proximal stent segment 100 and near the distal stent segment 200 are located on the same side of the first cross-section; or, the ends of the keel line 600 near the proximal stent segment 100 and near the distal stent segment 200 are located on opposite sides of the first cross-section.

[0106] It should be noted that the keel line 600 is connected to the proximal support segment 100, the arch support segment 300, and the distal support segment 200, respectively. Figure 6 and Figure 7 The diagram showing the connection between the keel line 600 and the proximal support segment 100 is omitted. It could be, for example... Figure 6As shown, the keel line 600 extends along the extension direction of the aortic stent 10, and the end of the keel line 600 near the proximal stent segment 100 and the end of the keel line 600 near the distal stent segment 200 are located on the same side of the first cross section; alternatively, as shown... Figure 7 As shown, the keel line 600 is arranged in a roughly spiral shape around the support cavity Q. In this way, the keel line 600 extends spirally from one end to the other around the central axis of the support cavity Q. Correspondingly, the end of the keel line 600 near the proximal support section 100 and the end of the keel line 600 near the distal support section 200 are located on opposite sides of the first cross section.

[0107] The keel 600 can be used to connect the proximal stent segment 100, the arch stent segment 300, and the distal stent segment 200, thereby improving the axial support force of the aortic stent 10 and further increasing the stability of the aortic stent 10 after implantation. In addition, the keel 600 is equivalent to a keel 600 that runs through the three segments of the proximal stent segment 100, the arch stent segment 300, and the distal stent segment 200. The keel 600 with a pre-bent shape can pre-bend the aortic stent 10, which is to say, pre-shape the aortic stent 10, so that the bending aortic stent 10 can better adapt to the curvature of the aortic arch 23.

[0108] With the keel line 600 extending along the extension direction of the aortic stent 10, the overall strength of the aortic stent 10 is high.

[0109] With the keel line 600 spirally extending from one end to the other around the central axis of the support cavity Q, the supporting force of the rear section on the front section can be increased, and the aortic stent 10 can better adapt to the torsion of the blood vessel, thus reducing damage to the blood vessel.

[0110] In some embodiments, the indicator 500 is disposed on the keel line 600 and is integrally formed with the keel line 600.

[0111] This improves the ease of manufacturing the indicator 500 and the keel line 600, reduces the number of parts in the aortic stent 10, and thus improves the manufacturing efficiency of the aortic stent 10.

[0112] In some embodiments, the arch stent segment 300 extends in a curved manner from one end near the proximal stent segment 100 to the end of the distal stent segment 200 away from the arch stent segment 300; and the branch vessel side 301 of the arch stent segment 300 is disposed around the first side 302 of the arch stent segment 300.

[0113] In this way, the aortic stent 10 can be pre-bent, that is, the aortic stent 10 can be pre-shaped, so that the bending aortic stent 10 can better adapt to the curvature of the aortic arch 23.

[0114] In some embodiments, the distal support segment 200 includes a plurality of second support wires 210 spaced apart along the extension direction of the covering film 400 on the distal support segment 200. Along the extension direction of the distal support segment 200, at least the second support wire 210 furthest from the arch support segment 300 includes a plurality of third bends 211 circumferentially connected along the support cavity Q, and a head portion 212 and a tail portion 213 connected to the head and tail of the plurality of third bends 211. All third bends 211 protrude in a direction parallel to one end of the distal support segment 200 furthest from the arch support segment 300, pointing towards the other end of the distal support segment 200, with adjacent third bends 211 protruding in opposite directions. The head portion 212 and the tail portion 213 extend in a direction opposite to the protrusion direction of adjacent third bends 211.

[0115] It can be understood that the extension direction of the film 400 on the distal stent segment 200 is the extension direction of the second film portion 420. Typically, the second support wire 210 furthest from the arch stent segment 300 protrudes from the cover 400 along the extension direction of the first cover portion 410. Therefore, the second support wire 210 furthest from the arch stent segment 300 needs to be configured to include multiple third bends 211, a head portion 212, and a tail portion 213. The remaining second support wires 210 may include multiple third bends 211 connected circumferentially along the support lumen Q. The remaining second support wires 210 may also include multiple third bends 211, a head portion 212, and a tail portion 213. With the head portion 212 and the tail portion 213 extending in the opposite direction to the protrusion direction of the third bends 211, the head portion 212 and the tail portion 213 can be well positioned along the vessel wall, reducing the possibility of the second support wire 210 furthest from the arch stent segment 300 puncturing the vessel wall due to its intersection with the vessel wall, and improving the safety of the distal stent segment 200 and the aortic stent 10.

[0116] Optionally, the head portion 212 and the tail portion 213 are bent inward along the radial direction of the support cavity Q at one end away from the adjacent third bend portion 211.

[0117] This can better reduce the chance of the second support wire 210, which is furthest from the arch stent segment 300, puncturing the blood vessel wall.

[0118] In some embodiments, the proximal stent segment 100 includes a plurality of third support wires 110 spaced apart along the extension direction of the covering film 400 on the proximal stent segment 100. Each third support wire 110 includes a plurality of fourth bends 111 connected circumferentially along the support cavity Q. All fourth bends 111 protrude in a direction parallel to one end of the proximal stent segment 100 away from the arched stent segment 300 and pointing towards the other end of the proximal stent segment 100. Adjacent fourth bends 111 protrude in opposite directions.

[0119] It can be understood that the extension direction of the membrane 400 on the proximal stent segment 100 is the extension direction of the first membrane portion 410.

[0120] This facilitates the improvement of the strength of the proximal stent segment 100, thereby improving the strength and reliability of the aortic stent 10.

[0121] In some embodiments, at least a portion of the proximal stent segment 100 is covered within the membrane 400.

[0122] Specifically, the membrane 400 includes a first membrane layer and a second membrane layer stacked together, and at least a portion of the proximal stent segment 100 is disposed between the first membrane layer and the second membrane layer.

[0123] Optionally, at least a portion of the proximal stent segment 100 may be disposed between the first and second membrane layers by sewing.

[0124] The proximal stent segment 100, located away from the arch stent segment 300, has a partially exposed or non-exposed design. Compared to designs with more exposure, this reduces the risk of aortic stent 10 damaging the descending aorta 21.

[0125] In some embodiments, at least a portion of the distal stent segment 200 is covered within the membrane 400.

[0126] Optionally, at least a portion of the distal stent segment 200 may be disposed between the first and second membrane layers by sewing.

[0127] Compared to designs with more exposed areas, this reduces the risk of damage to the ascending aorta 22 caused by the aortic stent 10.

[0128] In some embodiments, the overcoat 400 includes a first overcoat portion 410 and a second overcoat portion 420 spaced apart from each other. The first overcoat portion 410 is applied to the proximal stent segment 100, and the second overcoat portion 420 is applied to the distal stent segment 200. The first overcoat portion 410 is also applied to one end of the arch stent segment 300 near the proximal stent segment 100, and the second overcoat portion 420 is also applied to one end of the arch stent segment 300 near the distal stent segment 200.

[0129] In this way, the lining 400 can be used to connect the proximal stent segment 100, the arch stent segment 300 and the distal stent segment 200, thereby improving the overall integrity of the aortic stent 10.

[0130] After implantation, the aortic stent 10 of this application is placed in the ascending aorta 22, aortic arch 23 and descending aorta 21 of the aorta using an overall fixation method. The overall fixation method does not rely on the supporting force of the aortic stent 10, which can reduce the risk of damage to the ascending aorta.

[0131] The aortic stent 10 includes a proximal stent segment 100, an arch stent segment 300, and a distal stent segment 200. It can be understood that the aortic stent 10 is a three-segment integral stent structure, which can better simulate the natural curvature of human blood vessels and reduce stimulation and damage to blood vessels.

[0132] In addition, the aortic stent 10 has a three-dimensional helical shape, which gives it good biomechanical properties. This allows the aortic stent 10 to better adapt to various deformations of the aorta caused by human movement, effectively reducing the elastic recoil force of the aortic stent 10 and thus improving its flexibility.

[0133] Because the arched stent segment 300 extends in a curved manner from the end near the proximal stent segment 100 to the end of the distal stent segment 200 away from the arched stent segment 300, the aortic stent 10 can be placed close to the vessel wall. The arched stent segment 300 is exposed outside the cladding 400, which can improve the torsional compliance of the aortic stent 10. By being set along the tortuous path of the blood vessel, the aortic stent 10 has better stress compliance.

[0134] In this application, the length of the bow support section 300 can be selected according to actual operational needs, along the direction from one end of the bow support section 300 near the proximal support section 100 to the other end.

[0135] It should be noted that the longer the arch stent segment 300 is, the better the torsional compliance of the aortic stent 10 will be. Of course, the length of the arch stent segment 300 should not be too long, and it is necessary to ensure that there is a covering 400 corresponding to the lesion. That is, the arch stent segment 300 should not pass through the lesion as much as possible.

[0136] This application also provides a method for manufacturing an aortic stent 10, comprising:

[0137] S10. Provide a proximal stent segment 100 for implantation in the descending aorta 21, a distal stent segment 200 for implantation in the ascending aorta 22, and an aortic arch stent segment 300 for implantation in the aortic arch 23; wherein the aortic arch stent segment 300 is located between the proximal stent segment 100 and the distal stent segment 200, and is connected to the proximal stent segment 100 and the distal stent segment 200, respectively.

[0138] S20, with a foldable coating 400.

[0139] It is understandable that the membrane 400 has a certain degree of elasticity, and the portion of the membrane 400 covering the proximal stent segment 100 can be stretched and extended along the extension direction of the proximal stent segment 100, and the portion of the membrane 400 covering the distal stent segment 200 can also be stretched and extended along the extension direction of the distal stent segment 200.

[0140] S30. The covering film 400 is applied to the proximal stent segment 100 and the distal stent segment 200.

[0141] S40, provides a keel line 600 with a pre-bent shape.

[0142] S50, the keel line 600 is passed through the proximal support section 100, the arch support section 300 and the distal support section 200, that is, the keel line 600 is connected to the proximal support section 100, the arch support section 300 and the distal support section 200 respectively.

[0143] Among them, the proximal stent segment 100, the arch stent segment 300, and the distal stent segment 200 together define a support cavity Q.

[0144] In some embodiments, step S20 of providing the elastic coating 400 specifically includes:

[0145] S21. Provide initial coating material 4001 (such as...) Figure 8 (As shown).

[0146] S22, the initial coating material 4001 is sandwiched between the first mold 71 with an external textured structure 711 and the second mold 72 with an internal textured structure 721 (which can be combined). Figure 8 and Figure 9 (To understand).

[0147] One of the outer texture structure 711 and the inner texture structure 721 is a raised structure, and the other of the outer texture structure 711 and the inner texture structure 721 is a groove structure adapted to the raised structure.

[0148] S23. Using the first mold 71 and the second mold 72, the initial coating material is hot-pressed to obtain a coating 400 (e.g., Figure 10 (As shown).

[0149] Alternatively, steps S21-S23 can be used to first form one of the portions of the membrane 400 covering the proximal stent segment 100 and the portions of the membrane 400 covering the distal stent segment 200, and then steps S21-S23 can be used to form the other of the portions of the membrane 400 covering the proximal stent segment 100 and the portions of the membrane 400 covering the distal stent segment 200. Figure 10 A schematic diagram of the structure of the first diaphragm portion 410 (i.e., the portion of the diaphragm 400 covering the proximal stent segment 100) formed using the manufacturing method of the aortic stent 10 of this application is provided.

[0150] Alternatively, the initial coating material can be hot-pressed using steps S21-S23. After the hot-pressing operation is completed, the initial coating material can be cut or trimmed to obtain the portion of the coating 400 covering the proximal support segment 100 and the portion of the coating 400 covering the distal support segment 200, respectively.

[0151] The outer texture structure 711 is adapted to the inner texture structure 721. The second mold 72 includes a first mold post 722. The inner texture structure 721 includes a plurality of arc-shaped protrusions 7211 spaced along the axial direction of the first mold post 722 on the inner peripheral wall of the first mold post 722.

[0152] It is understood that a second annular groove is provided between two adjacent arc-shaped protrusions 7211. In this way, the initial coating material is hot-pressed between the outer textured structure 711 and the inner textured structure 721, so that the formed coating 400 is wavy. This is beneficial for the portion of the coating 400 covering the proximal stent segment 100 to stretch and extend along the extension direction of the proximal stent segment 100, and also for the portion of the coating 400 covering the distal stent segment 200 to stretch and extend along the extension direction of the distal stent segment 200. This allows the aortic stent 10 to have better compressibility, effectively reducing the elastic recoil force of the aortic stent 10, thereby improving the flexibility of the aortic stent 10 and thus improving the reliability of the aortic stent 10.

[0153] Figure 11 This demonstrates the direct replacement of the initial coating material 4001 with... Figure 1 The schematic diagram of the coating 400 shown is compared with... Figure 1 and Figure 11 It is known that the aortic stent 10 made using the lining 400 of this application has better bending effect and better compressibility, which can effectively reduce the elastic recoil force of the aortic stent 10, thereby improving the flexibility of the aortic stent 10, thus improving the reliability of the aortic stent 10, and also reducing the elastic recoil force inherent in the aortic stent 10, improving the flexibility of the aortic stent 10, and reducing complications caused by poor wall apposition.

[0154] It should be noted that, Figure 11 In the middle, the keel line 600 has a pre-bent shape and is located on the branch vessel side 301.

[0155] In some embodiments, the hot pressing process parameters for hot pressing the initial coating material by means of the first mold 71 and the second mold 72 include: hot pressing temperature of 60℃-80℃; hot pressing time of 10s-20s.

[0156] For example, the hot pressing temperature is 60°C, 70°C, or 80°C; the hot pressing time is 10s, 15s, or 20s.

[0157] Setting the hot-pressing temperature and time within a suitable range can improve the hot-pressing effect without causing thermal damage to the initial coating material, thereby enabling the aortic stent 10 to have better compressibility.

[0158] In some embodiments, the second mold 72 includes a first sub-mold 7201 and a second sub-mold 7202 arranged radially along the first mold 71. The first mold 71 is inserted into the initial coating material. The second mold 72 has a closed state and an open state. In the closed state, the first sub-mold 7201 and the second sub-mold 7202 are closed together and jointly fitted onto the initial coating material. In the open state, the first sub-mold 7201 and the second sub-mold 7202 are separated from each other. Both the first sub-mold 7201 and the second mold 7202 include a first mold post 722 and an internal texture structure 721.

[0159] Specifically, the cross-sections of the first sub-mold 7201 and the second sub-mold 7202 are approximately semi-circular. In the closed state, the first sub-mold 7201 and the second sub-mold 7202 close together, and the cross-section of the second mold 72 is approximately circular.

[0160] One of the first sub-mold 7201 and the second sub-mold 7202 can be fixedly set, and pressure can be applied to the other of the first sub-mold 7201 and the second sub-mold 7202 by a hydraulic cylinder or a pneumatic cylinder.

[0161] The material of the lining 400 may be polyester or other materials that can form an elastic lining 400 and be applied to the aortic stent 10.

[0162] The manufacturing method of the aortic stent 10 of this application can make the cladding 400 elastic, increase the shingling effect of the aortic stent 10, improve the bird's beak phenomenon of the aortic stent 10, make the aortic stent 10 have better compressibility, effectively reduce the elastic recoil force of the aortic stent 10, thereby improving the flexibility of the aortic stent 10 and thus improving the reliability of the aortic stent 10.

[0163] In some embodiments, step S40 of providing the keel wire 600 with a pre-bent shape specifically includes:

[0164] S41, Provide initial keel materials.

[0165] S42. Place the initial keel material in the shaping mold 80 to form a keel line 600 with a pre-bent shape.

[0166] The shaping mold 80 has a curved groove 801 that matches the keel line 600 (e.g., Figure 12 (As shown).

[0167] Thus, the keel line 600 can be shaped by the shaping mold 80 to form a keel line 600 with a pre-bent shape.

[0168] In some embodiments, the initial keel material is placed in a shaping mold, and the shaping process parameters include: shaping temperature of 480℃-520℃; shaping time of 10min-15min.

[0169] For example, the setting temperature is 480°C, 500°C, or 520°C, and the setting time is 10 min, 12.5 min, or 15 min.

[0170] By setting the setting temperature within a suitable range, such as 480℃-520℃, and setting the setting time within a suitable range, such as 10min-15min, the initial keel material can be better shaped under high temperature conditions through the setting mold 80, which is more conducive to forming a keel line 600 with a pre-bent shape.

[0171] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0172] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A method for manufacturing an aortic stent, characterized in that, include: Provided a proximal stent segment for implantation in the descending aorta, a distal stent segment for implantation in the ascending aorta, and an arch stent segment for implantation in the aortic arch; wherein the arch stent segment is located between the proximal stent segment and the distal stent segment, and is connected to the proximal stent segment and the distal stent segment respectively. A foldable coating is provided; The covering film is applied to the proximal stent segment and the distal stent segment; Provide keel wire with a pre-curved shape; and The keel line passes through the proximal support segment, the arch support segment, and the distal support segment; The proximal stent segment, the arch stent segment, and the distal stent segment together define a support cavity; The arch stent segment is a bare stent segment; the arch stent segment is provided with a plurality of first holes communicating with the support cavity, and the first holes are used to communicate with branch vessels on the aortic arch; The covering film is foldable, so that the portion of the covering film applied to the proximal stent segment can be folded along the bending direction of the proximal stent segment, and the portion of the covering film applied to the distal stent segment can be folded along the bending direction of the distal stent segment. The foldable coating specifically includes: Provide initial coating materials; The initial coating material is sandwiched between a first mold with an external textured structure and a second mold with an internal textured structure; The initial coating material is hot-pressed using the first mold and the second mold to obtain the coating; The second mold includes a first mold column, and the inner texture structure includes a plurality of arc-shaped protrusions spaced along the axial direction of the first mold column on the inner peripheral wall of the first mold column; the outer texture structure is a groove structure adapted to the arc-shaped protrusions.

2. The method for manufacturing an aortic stent according to claim 1, characterized in that, The hot pressing process parameters for hot pressing the initial coating material using the first mold and the second mold include: hot pressing temperature of 60℃-80℃; hot pressing time of 10s-20s.

3. The method for manufacturing an aortic stent according to claim 1, characterized in that, The provision of the keel wire with a pre-bent shape specifically includes: Provide initial keel materials; The initial keel material is placed in a shaping mold to form the keel line with a pre-bent shape; The shaping mold has a curved groove adapted to the keel line.

4. The method for manufacturing an aortic stent according to claim 3, characterized in that, The shaping process parameters for placing the initial keel material in the shaping mold include: shaping temperature of 480℃-520℃; shaping time of 10min-15min.

5. An aortic stent, characterized in that, The aortic stent is prepared using the manufacturing method of the aortic stent according to any one of claims 1-4.

6. The aortic stent according to claim 5, characterized in that, Along the radial direction of the supporting cavity, the arched stent segment has a branch vessel side and a first side disposed opposite to each other; All the first holes are located on the branch vessel side of the arched stent segment; The first side of the bow support section is provided with a plurality of second holes communicating with the support cavity; Wherein, the diameter of the second hole is smaller than the diameter of the first hole; The bow support section is constructed as a grid structure, and the grid structure has multiple nodes. Within a predetermined area on the branch vessel side of the arched stent segment, the number of nodes in the mesh structure is a first number; Within the preset area region on the first side of the bow support section, the number of nodes in the grid structure is a second number; Wherein, the first quantity is less than the second quantity; The grid structure includes multiple first support wires, each first support wire having multiple first bends and multiple second bends arranged alternately along the circumference of the support cavity; the first bends and adjacent second bends have opposite bending directions and are spaced apart along the extension direction of the bow support section; in two adjacent first support wires, the first bend of one first support wire is hooked to the second bend of the other first support wire to form a node.

7. The aortic stent according to claim 6, characterized in that, The first side of the bow support section is used to achieve a bending effect of 0~270°.

8. The aortic stent according to claim 6, characterized in that, In the first region, at least one non-node portion is provided between two adjacent node portions. The non-node portion is the part where two adjacent first support wires intersect each other on the orthographic projection of the target plane, and is the part where the two adjacent first support wires are not connected to each other. The target plane is perpendicular to the branch vessel side and points towards the first side.

9. The aortic stent according to claim 6, characterized in that, The aortic stent also includes an indicator on the proximal stent segment or the distal stent segment; The indicator is used to indicate the direction of the proximal stent segment relative to the distal stent segment in the extension direction parallel to the proximal stent segment, and to indicate the direction of the branch vessel side relative to the first side in the radial direction of the support lumen.

10. The aortic stent according to claim 5, characterized in that, The aortic stent has a first cross section extending along the axial direction of the supporting lumen; the end of the keel line near the proximal stent segment and the end of the keel line near the distal stent segment are located on the same side of the first cross section; or, the end of the keel line near the proximal stent segment and the end of the keel line near the distal stent segment are located on opposite sides of the first cross section.

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