Self-generating interbody fusion cage and preparation method thereof

By combining 3D-printed porous tantalum stents with bioactive piezoelectric ceramics, the problem of insufficient biocompatibility and bone integration capabilities of existing intervertebral fusion device materials is solved, and an efficient intervertebral fusion effect is achieved.

CN120501924APending Publication Date: 2025-08-19SHANGHAI TENTH PEOPLES HOSPITAL
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Patent Information

Application Number
CN202510460933.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-14
Publication Date
2025-08-19

AI Technical Summary

Technical Problem

The existing intervertebral fusion device materials have shortcomings in terms of biocompatibility, osseous integration capability and mechanical strength, resulting in poor fusion rate after implantation, and the existing methods are complex in operation and easy to fall off.

Method used

Porous tantalum stents are prepared by 3D printing technology, and bioactive piezoelectric ceramics are combined on it, including barium titanate and hydroxyapatite. They use mechanical forces in the human body to self-generate and promote bone formation, and bioactive piezoelectric ceramics are prepared by high-temperature sintering and polarization treatment.

Benefits of technology

Self-generating power promotes intervertebral fusion, improves bone graft fusion rate, reduces stress masking effect, enhances biocompatibility and mechanical properties, and promotes the proliferation and differentiation of bone cells.

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Abstract

The invention relates to a self-generating interbody fusion cage and a preparation method thereof, the interbody fusion cage comprises a porous tantalum support and bioactive piezoelectric ceramic arranged on the porous tantalum support, and the bioactive piezoelectric ceramic comprises hydroxyapatite and barium titanate; the preparation method comprises the following steps that the porous tantalum support is obtained through 3D printing, assembling positions of the bioactive piezoelectric ceramics are reserved on the upper surface and the lower surface of the porous tantalum support, the bioactive piezoelectric ceramics are embedded into the assembling positions of the upper surface and the lower surface of the porous tantalum support, and the weight ratio of barium titanate to hydroxyapatite is (92-98): (2-8). Compared with the prior art, the vertebral fusion cage has the advantages of promoting vertebral fusion by utilizing mechanical force in a human body to generate electricity, matching mechanical properties of a contact surface of the fusion cage, providing osteogenesis related ions, being relatively good in interface combination and the like.
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