Traditional Chinese medicine prescription for treating bedsores and pressure sores and preparation method of traditional Chinese medicine prescription

Abstract

The invention relates to the field of traditional Chinese medicine preparations, and discloses a traditional Chinese medicine prescription for treating bedsores and pressure sores, which is prepared from the following raw material medicines in parts by weight: 5-15 parts of astragalus membranaceus, 5-15 parts of safflower carthamus, 5-15 parts of angelica sinensis and 3-10 parts of chinaberry seeds. The technical core is that the raw material medicines are specifically processed, wherein the radix astragali is honey-fried radix astragali, the safflower is low-temperature dried safflower, the Chinese angelica is wine-fried Chinese angelica, and the chinaberry seed is vinegar-quenched and calcined chinaberry seed. The preparation method comprises the following steps: respectively processing the medicinal materials, mixing the processed products, and crushing into fine medicine powder capable of passing through a sieve of 80-120 meshes. Through a targeted processing technology, the targeted effects of tonifying qi, promoting tissue regeneration, promoting blood circulation to remove blood stasis, clearing heat and drying dampness of all the components are remarkably enhanced, the four medicines have a synergistic effect, purgation and tonification are combined, and the pathological state of the wound surface is comprehensively improved.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine prescription for treating bedsores and pressure sores and a preparation method thereof. Background Art

[0002] Bedsores are caused by prolonged pressure on localized tissue, leading to impaired circulation, persistent ischemia and hypoxia, and subsequently, tissue ulceration and necrosis. These conditions are common in patients who are bedridden, paralyzed, elderly, or have limited mobility, and are a thorny and common problem in clinical care. Bedsores not only cause significant pain to patients, but also make the wounds difficult to heal and prone to infection. In severe cases, they can lead to life-threatening complications such as sepsis, significantly impacting patients' quality of life and significantly increasing the burden of medical care.

[0003] At present, the treatment of bedsores mainly includes two approaches: Western medicine and traditional Chinese medicine. Conventional treatment methods of Western medicine focus on strengthening nutritional support, frequent turning over to reduce pressure, and wound care, such as the use of various functional dressings, debridement, and topical antibiotics. These methods play an important role in prevention and basic care, but for bedsores that have already formed, especially those that are more serious, the treatment process is often long and the results are not satisfactory. Existing topical medications often have a single function, or focus on anti-infection, or focus on simply promoting granulation growth. It is difficult to fully take into account the multiple complex links in the pathological process of bedsores, such as blood circulation disorders, inflammatory exudates, tissue necrosis, and insufficient regeneration and repair. Therefore, the comprehensive therapeutic effect is limited.

[0004] Traditional Chinese medicine has accumulated rich experience in the treatment of surface ulcers, and external use Chinese herbal prescriptions are one of its important treatment methods. However, existing external use Chinese herbal preparations also have shortcomings in their application. The preparation process of many prescriptions is relatively extensive, and the raw medicinal materials are often simply crushed and mixed, and the effective ingredients of the medicinal materials are not fully released and guided through specific processing processes, thereby limiting the effectiveness of the medicine. In addition, some prescriptions fail to achieve an optimized combination for the core pathological conditions of bedsores in terms of compatibility, resulting in their role in promoting blood circulation and removing blood stasis, improving local microcirculation, and invigorating qi and strengthening the body's self-repair ability. It is not prominent, affecting the ultimate healing speed and quality. Therefore, it is of great clinical value and practical significance to develop a Chinese medicine composition with a precise formula, unique process, and the ability to synergistically act on multiple pathological links of bedsores, thereby significantly improving the efficacy. Summary of the Invention

[0005] The present invention aims to solve the technical problems of the existing methods for treating bedsores and pressure sores, such as slow healing speed, insufficient comprehensive efficacy, and failure of the preparation process to fully exert the efficacy of the medicine.

[0006] To achieve the above objectives, the present invention is implemented through the following technical scheme: a traditional Chinese medicine prescription for treating bedsores and pressure sores, prepared from the following raw materials in parts by weight: 5 to 15 parts of astragalus, 5 to 15 parts of safflower, 5 to 15 parts of angelica, and 3 to 10 parts of chinaberry; wherein the astragalus is honey-roasted astragalus, the safflower is safflower that has been low-temperature dried, the angelica is wine-roasted angelica, and the chinaberry is vinegar-quenched chinaberry.

[0007] Preferably, the amount of refined honey used in the preparation of the honey-roasted Astragalus is 25% to 30% of the weight of the Astragalus, and the amount of wine used in the preparation of the wine-roasted Angelica is 10% to 15% of the weight of the Angelica.

[0008] Preferably, the amount of rice vinegar used in the preparation of the vinegar-quenched chinaberry fruits is 15% to 20% of the weight of the chinaberry fruits.

[0009] Preferably, the Chinese medicine prescription is in the form of a powder, and the powder passes through an 80-120 mesh sieve.

[0010] Preferably, a method for preparing a traditional Chinese medicine prescription for treating bedsores and pressure sores comprises the following steps: S1. Medicinal material processing: Astragalus, safflower, Chinese angelica, and Melia azedarach were processed separately to obtain honey-roasted Astragalus, low-temperature-dried safflower, wine-roasted Chinese angelica, and vinegar-quenched Melia azedarach; S2. Mixing and pulverizing: Mix the processed medicinal materials obtained in step S1 and pulverize them into medicinal powder.

[0011] Preferably, in step S1, the step of preparing the honey-roasted astragalus comprises: moistening the astragalus with refined honey in an amount of 25% to 30% by weight of the astragalus, and then stir-frying the astragalus at 100 to 130°C.

[0012] Preferably, in step S1, the step of preparing the wine-fried angelica comprises: using 10% to 15% of the weight of the angelica to wine-soak the angelica, and then drying it at 50 to 60°C.

[0013] Preferably, in step S1, the step of preparing the vinegar-quenched chinaberry fruits comprises: calcining the chinaberry fruits with high heat until the surface is burnt black and the inside is burnt yellow, and then quenching them with rice vinegar containing 15% to 20% of the weight of the chinaberry fruits.

[0014] Preferably, in step S1, the step of low-temperature drying the safflower is carried out at a temperature of 40 to 55° C. under vacuum or forced ventilation conditions.

[0015] Preferably, in step S2, the pulverizing step is to pulverize the mixed medicinal materials until they can pass through an 80-120 mesh sieve.

[0016] Honey-Roasted Astragalus: While raw Astragalus tends to strengthen the exterior, honey-roasted Astragalus has a warming effect, significantly enhancing its efficacy in tonifying the middle and replenishing Qi, expelling toxins, and promoting tissue regeneration. This provides a stronger material foundation for wound healing and accelerates the growth of granulation tissue.

[0017] Wine-Roasted Angelica: Wine has a penetrating and dispersing nature. After being roasted with wine, Angelica's ability to invigorate blood circulation, dissipate blood stasis, and activate meridians is greatly stimulated. This can more effectively improve the microcirculatory impairment caused by prolonged pressure on bedsores, creating conditions for tissue repair.

[0018] Low-temperature drying of safflower: Some of the blood-activating active ingredients in safflower (such as safflower glycosides) are volatile or thermally unstable. This invention utilizes a low-temperature drying process to maximize the retention of these active ingredients, ensuring their full potential for promoting blood circulation, removing blood stasis, and promoting menstruation and alleviating pain.

[0019] Vinegar-quenched Melia azedarach seeds: Melia azedarach seeds have the effects of clearing heat and dampness, killing insects and relieving itching, but they are cold and irritating when used raw. The "calcination" method enhances their ability to astringe and dry dampness, effectively controlling wound exudation; while "vinegar quenching" guides the drug into the liver meridian, alleviating its coldness and irritation, while also enhancing its effect of promoting qi and relieving pain. The four herbs of the present invention are combined, with honey-roasted Astragalus and wine-roasted Angelica as the main and auxiliary herbs, to achieve the primary functions of invigorating qi and nourishing blood, activating blood circulation and promoting tissue regeneration; low-temperature safflower as the auxiliary herb, to enhance the blood circulation and blood stasis-removing effect; and vinegar-quenched Melia azedarach as the auxiliary herb, to clear away heat and dampness, astringe and relieve pain, and counteract the warming and drying properties of other herbs. The four herbs are used together to achieve both attacking and tonifying effects, enabling the composition to exert significant effects in the three key aspects of improving local blood circulation, controlling inflammatory exudation, and promoting tissue regeneration.

[0020] The present invention provides a traditional Chinese medicine prescription for treating bedsores and pressure sores and a preparation method thereof. It has the following beneficial effects: This formula utilizes honey-roasted Astragalus and wine-roasted Angelica to tonify Qi and nourish the blood, promoting blood circulation and removing blood stasis, improving wound microcirculation and nutrient supply. Low-temperature-dried safflower enhances blood circulation, while vinegar-quenched Melia azedarach fruit clears heat and dampness, controlling exudation and infection. These four herbs, combined after specific preparation, enable this formula to simultaneously improve local blood circulation, control inflammatory exudation, and promote tissue regeneration, achieving both attacking and replenishing effects, enabling a more comprehensive and effective treatment of the complex wound conditions of bedsores (pressure sores).

[0021] 2. This invention utilizes targeted processing methods for each of the medicinal ingredients in the formula, rather than simply mixing and pulverizing them. For example, honey-roasting Astragalus enhances its Qi-tonifying and muscle-reinforcing properties; wine-roasting Angelica strengthens its blood-activating and collateral-dredging properties; low-temperature drying of Carthamus tinctorius preserves its core blood-activating components; and vinegar-quenching and calcining of Melia azedarach enhances its astringent, dampness-drying, anti-inflammatory, and analgesic properties. This refined pretreatment allows the efficacy of each ingredient to be highly targeted at the pathological aspects of bedsores (pressure sores), achieving synergistic efficacy and overall improved treatment results.

[0022] 3. The present invention prepares the composition into a fine powder capable of passing through an 80-120 mesh sieve, greatly increasing the specific surface area of ​​the drug in contact with the wound surface, significantly promoting the dissolution and absorption of the active ingredient, thereby accelerating the onset of action. Furthermore, the powder within this particle size range has good adhesion, forming a uniform protective layer of the drug, and exhibits minimal physical irritation to new granulation tissue, thereby improving patient comfort and safety and ensuring sustained, stable therapeutic effects. DETAILED DESCRIPTION

[0023] The following is a clear and complete description of the technical solutions of the present invention. It should be understood that the embodiments described are only a portion of the embodiments of the present invention, not all of them. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without inventive effort are intended to fall within the scope of protection of the present invention.

[0024] Example: Example 1 This embodiment provides a method for preparing a traditional Chinese medicine composition.

[0025] Weigh the raw material: Astragalus: 5kg Safflower: 5kg Angelica: 5kg Chinaberry: 3kg Preparation of medicinal materials: (1) Honey-roasted Astragalus: Take 5 kg of the Astragalus slices and 1.25 kg of refined honey (equivalent to 25% of the weight of the Astragalus). Dilute the refined honey with a small amount of boiling water, mix well with the Astragalus slices, and let them sit for 40 minutes. Then, place them in a frying pan and stir-fry over low heat at 100°C until the surface turns golden brown and is no longer sticky. Remove and let cool.

[0026] (2) Low-temperature drying of safflower: 5 kg of safflower was placed in a vacuum drying oven and dried at 40°C and 0.08 MPa vacuum for 6 hours to a constant weight.

[0027] (3) Wine-roasted Angelica: Take 5 kg of the above-mentioned Angelica slices, spray them with 0.5 kg of yellow rice wine (equivalent to 10% of the weight of the Angelica), mix well, and let them soak for 30 minutes. Then dry them in a 50°C oven to constant weight.

[0028] (4) Vinegar-quenching Melia azedarach: Take 3 kg of Melia azedarach fruits and place them in a calcining pot over high heat until the surface is charred black and the inside is burnt yellow. Immediately spray 0.45 kg of rice vinegar (equivalent to 15% of the weight of the Melia azedarach fruits) while they are still hot to quench them. Remove and air dry.

[0029] Mixing and crushing: The honey-roasted astragalus, low-temperature dried safflower, wine-roasted angelica and vinegar-quenched chinaberry fruits that have been processed and cooled are evenly mixed, crushed using an ultrafine grinder, and passed through an 80-mesh sieve to obtain the product.

[0030] Example 2 This embodiment provides a method for preparing a traditional Chinese medicine composition.

[0031] Weigh the raw material: Astragalus: 10kg Safflower: 10kg Angelica: 10kg Neem: 6kg Preparation of medicinal materials: (1) Honey-roasted Astragalus: Take the 10 kg Astragalus slices and 2.8 kg refined honey (equivalent to 28% of the weight of the Astragalus). Dilute the refined honey with a small amount of boiling water, mix well with the Astragalus slices, and let them sit for 50 minutes. Then, place them in a frying pan and stir-fry over low heat at 115°C until the surface turns golden brown and is no longer sticky. Remove and let cool.

[0032] (2) Low-temperature drying of safflower: 10 kg of safflower was placed in a forced ventilation drying oven at 50°C and a wind speed of 1.0 m / s for 8 hours to a constant weight.

[0033] (3) Wine-cured Angelica: Take 10 kg of the above-mentioned Angelica slices and spray them with 1.2 kg of 35% (v / v) ethanol solution (equivalent to 12% of the weight of the Angelica) and mix thoroughly. Let it sit for 35 minutes. Then, dry it in a 55°C oven to constant weight.

[0034] (4) Vinegar-quenching Melia azedarach: Take 6 kg of Melia azedarach fruits and place them in a calcining pot over high heat until the surface is charred black and the inside is burnt yellow. While still hot, immediately spray 1.08 kg of rice vinegar (equivalent to 18% of the weight of the Melia azedarach fruits) to quench the mixture. Remove the mixture and air dry.

[0035] Mixing and crushing: The above-prepared and cooled medicinal materials are mixed evenly, crushed using a jet mill, and passed through a 100-mesh sieve to obtain the product.

[0036] Example 3 This embodiment provides a method for preparing a traditional Chinese medicine composition.

[0037] Weigh the raw material: Astragalus: 15kg Safflower: 15kg Angelica: 15kg Neem: 10kg Preparation of medicinal materials: (1) Honey-roasted Astragalus: Take the 15 kg Astragalus slices and 4.5 kg refined honey (equivalent to 30% of the weight of the Astragalus). Dilute the refined honey with a small amount of boiling water, mix well with the Astragalus slices, and let them sit for 60 minutes. Then, place them in a frying pan and stir-fry over low heat at 130°C until the surface turns golden brown and is no longer sticky. Remove and let cool.

[0038] (2) Low-temperature drying of safflower: 15 kg of safflower was placed in a vacuum drying oven and dried at 55°C and 0.07 MPa vacuum for 4 hours to a constant weight.

[0039] (3) Wine-roasted Angelica: Take 15 kg of the above-mentioned Angelica slices, spray them with 2.25 kg of yellow rice wine (equivalent to 15% of the weight of the Angelica), mix well, and let them soak for 40 minutes. Then, dry them in a 60°C oven to constant weight.

[0040] (4) Vinegar-quenching Melia azedarach: Take 10 kg of Melia azedarach fruits and place them in a calcining pot over high heat until the surface is charred black and the inside is burnt yellow. Immediately spray 2.0 kg of rice vinegar (equivalent to 20% of the weight of the Melia azedarach fruits) while they are still hot to quench them. Remove and air dry.

[0041] Mixing and crushing: The above-prepared and cooled medicinal materials are mixed evenly, crushed using an ultrafine grinder with a grading wheel, and passed through a 120-mesh sieve to obtain the product.

[0042] Comparative Example: Comparative Example 1 Compared with Example 2, the difference is that the astragalus, safflower, angelica, and chinaberry fruit are all raw medicinal pieces, without any processing such as honey roasting, wine roasting, low-temperature drying, or vinegar quenching. The four raw medicinal materials are directly mixed and then crushed. The other preparation conditions are the same as those in Example 2.

[0043] Comparative Example 2 Compared with Example 2, the difference is that the safflower is dried using a conventional high-temperature drying method, that is, dried in a forced air drying oven at 80° C. to a constant weight. The other preparation conditions are the same as those in Example 2.

[0044] Comparative Example 3 Compared to Example 2, the difference lies in the following: the amounts of the processing excipients exceed the limits of the present invention. Specifically, when preparing astragalus with honey, the amount of refined honey is 40% of the weight of the astragalus; when preparing angelica with wine, the amount of wine is 20% of the weight of the angelica. All other preparation conditions are the same as in Example 2.

[0045] Comparative Example 4 Compared with Example 2, the difference is that in the final pulverization step, the mixed medicinal materials are only pulverized until all of them pass through a 40-mesh sieve. The other preparation conditions are the same as those in Example 2.

[0046] Test experiment: Pharmacodynamic evaluation experiment In order to verify the beneficial effects of the Chinese medicine composition of the present invention, the following pharmacodynamic evaluation experiments were conducted.

[0047] 1. Experimental Materials Test samples: the medicinal powders prepared in Examples 1-3 and the medicinal powders prepared in Comparative Examples 1-4.

[0048] Control group: normal saline group.

[0049] Experimental animals: SD rats, weighing 220-250 g, half male and half female.

[0050] 2. Experimental Methods 2.1 Establishment of the animal pressure ulcer model Two round strong magnets with a diameter of 15 mm were used. The skin of the rat's back spine was prepared symmetrically on both sides and disinfected routinely. One magnet was placed under the skin and the other on the corresponding position on the skin surface, so that they attracted each other and clamped the skin. After 12 hours of continuous pressure, the magnets were removed to cause local skin ischemia and necrosis. 24 hours after modeling, the wound surface was round and dark purple, forming a standardized pressure ulcer model.

[0051] 2.2 Animal Grouping and Dosing Seventy-two rats successfully modeled were randomly divided according to body weight into nine groups of eight rats each. These groups were: normal saline group, comparative example group 1, comparative example group 2, comparative example group 3, comparative example group 4, example group 1, example group 2, and example group 3. Dosing began on the second day after successful modeling. The wound surface was cleaned with normal saline before dosing.

[0052] For each group, approximately 0.2 g of the corresponding drug powder was evenly applied to the wound surface and covered and secured with sterile gauze and medical tape. The saline group was covered with gauze soaked in saline. The dressing was changed daily for 14 consecutive days.

[0053] 3. Evaluation indicators and detection methods (1) Determination of wound healing rate: On days 0, 7, and 14 after administration, the long diameter (a) and short diameter (b) of the wound were measured with a vernier caliper. The wound area was calculated according to the formula S = π × a × b / 4, and the wound healing rate on day 14 was also calculated.

[0054] Healing rate (%) = (wound area on day 0 - wound area on day 14) / wound area on day 0 × 100%.

[0055] (2) Wound exudate evaluation: On the third day after administration, accurately weigh the new sterile gauze before changing the dressing (W1). Carefully remove the gauze with exudate 24 hours after application and accurately weigh it again (W2). The weight gain (W2-W1) is used as an indicator of wound exudate.

[0056] (3) Determination of Hydroxyproline (HYP) Content in Wound Tissue At the end of the experiment (day 14), the rats were sacrificed, and the skin tissue at the wound healing site was completely peeled off and accurately weighed. Tissue homogenate was prepared by alkaline hydrolysis according to the kit instructions (Nanjing Jiancheng Bioengineering Institute, A030-2-1). The absorbance was measured at a wavelength of 550 nm using a spectrophotometer to calculate the hydroxyproline content in the tissue.

[0057] 4. Experimental results The data of each group were statistically processed and the results are shown in Table 1.

[0058] Table 1 Wound healing status and related indexes of rats in each group (x±s, n=8)

[0059] As shown in the experimental data in Table 1, Examples 1, 2, and 3 demonstrated significant superiority in wound healing rate, wound exudate control, and hydroxyproline content compared to the respective control examples and the normal saline group. This demonstrates that the technical solution of the present invention is not simply a stacking of medicinal materials, but rather a specific processing of each component to maximize its efficacy. Compared with Comparative Example 1 (direct pulverization of the raw medicinal materials), all indicators of the Example group were significantly improved, confirming that the combination of honey-fried Astragalus membranaceus, wine-fried Angelica sinensis, low-temperature dried Safflower, and vinegar-quenched Melia azedarach fruit synergistically enhances the efficacy of invigorating Qi and promoting tissue regeneration, promoting blood circulation and removing blood stasis, and astringing and drying dampness, thereby effectively improving wound pathology and accelerating the healing process.

[0060] Comparing the data of the Example group with those of Comparative Examples 2 and 3, it can be found that the specific parameters in the processing process are crucial. Comparative Example 2 uses conventional high-temperature drying of safflower, and its healing rate and hydroxyproline content are significantly lower than those of the Example group, indicating that the low-temperature drying process effectively protects the heat-sensitive active ingredients in safflower, which is the key to ensuring its blood circulation and blood stasis-removing efficacy. Similarly, the improper dosage of processing excipients in Comparative Example 3 also leads to its effect being weaker than that of the Example group, which proves that the precisely controlled excipient ratio in this solution is a necessary condition for achieving drug efficacy balance and optimization, ensuring the full play of the medicinal properties without excessive worry.

[0061] Furthermore, a comparison of the Example group with Comparative Example 4 (where the drug powder particle size was too coarse) demonstrates that preparing the drug powder into a fine powder capable of passing through an 80-120 mesh sieve is crucial for improving therapeutic efficacy. The Example group exhibited a higher healing rate and significantly higher hydroxyproline content than Comparative Example 4, demonstrating that the fine drug powder increased the contact area between the drug and the wound surface, promoting the dissolution and absorption of the active ingredient, thereby more effectively stimulating collagen synthesis and improving wound healing quality. This demonstrates that optimized formulation form is a key factor in ensuring the excellent technical effectiveness of this solution.

[0062] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese medicinal formula for treating bedsores and pressure sores, characterized in that: The invention is prepared from the following raw materials in parts by weight: 5-15 parts of astragalus, 5-15 parts of safflower, 5-15 parts of angelica, and 3-10 parts of chinaberry fruit; wherein the astragalus is honey-roasted astragalus, the safflower is low-temperature-dried safflower, the angelica is wine-roasted angelica, and the chinaberry fruit is vinegar-quenched chinaberry fruit.

2. A traditional Chinese medicine prescription for treating bedsores and pressure sores according to claim 1, characterized in that: The amount of refined honey used in the preparation of the honey-fried astragalus is 25% to 30% of the weight of the astragalus, and the amount of wine used in the preparation of the wine-fried angelica is 10% to 15% of the weight of the angelica.

3. A traditional Chinese medicine prescription for treating bedsores and pressure sores according to claim 1, characterized in that: In the preparation of the vinegar-quenched chinaberry fruits, the amount of rice vinegar used is 15% to 20% of the weight of the chinaberry fruits.

4. A traditional Chinese medicine prescription for treating bedsores and pressure sores according to claim 1, characterized in that: The Chinese medicine prescription is in the form of medicine powder, and the medicine powder passes through an 80-120 mesh sieve.

5. A method for preparing a traditional Chinese medicine prescription for treating bedsores and pressure sores according to any one of claims 1 to 4, characterized in that: The following steps are involved: S1. Medicinal material processing: Astragalus, safflower, Chinese angelica, and Melia azedarach were processed separately to obtain honey-roasted Astragalus, low-temperature-dried safflower, wine-roasted Chinese angelica, and vinegar-quenched Melia azedarach; S2. Mixing and pulverizing: Mix the processed medicinal materials obtained in step S1 and pulverize them into medicinal powder.

6. The method for preparing a traditional Chinese medicine prescription for treating bedsores and pressure sores according to claim 5, characterized in that: In step S1, the step of preparing the honey-roasted astragalus comprises: moistening the astragalus with refined honey in an amount of 25% to 30% by weight of the astragalus, and then stir-frying the astragalus at 100 to 130°C.

7. The method for preparing a traditional Chinese medicine prescription for treating bedsores and pressure sores according to claim 5, characterized in that: In step S1, the step of preparing the wine-fried angelica comprises: using 10% to 15% of the weight of the angelica to wine-soak the angelica, and then drying it at 50 to 60°C.

8. The method for preparing a traditional Chinese medicine prescription for treating bedsores and pressure sores according to claim 5, characterized in that: In step S1, the step of preparing the vinegar-quenched chinaberry fruits comprises: calcining the chinaberry fruits with high heat until the surface is burnt black and the inside is burnt yellow, and then quenching them with rice vinegar containing 15% to 20% of the weight of the chinaberry fruits.

9. The method for preparing a traditional Chinese medicine prescription for treating bedsores and pressure sores according to claim 5, characterized in that: In step S1, the low-temperature drying process of safflower is carried out at a temperature of 40-55° C. under vacuum or forced ventilation conditions.

10. The method for preparing a traditional Chinese medicine prescription for treating bedsores and pressure sores according to claim 5, characterized in that: In step S2, the pulverizing step is to pulverize the mixed medicinal materials until they can pass through an 80-120 mesh sieve.

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