Formula and preparation method of traditional Chinese medicine anti-hair loss pilatory

Abstract

The invention discloses a traditional Chinese medicine anti-hair-loss pilatory formula and a preparation method thereof, the traditional Chinese medicine anti-hair-loss pilatory formula comprises a cacumen biotae extract, a polygonum multiflorum extract, a herba ecliptae extract and other components, and a multi-target synergistic effect is realized through specific proportion compatibility. The preparation method comprises the steps of medicinal material pretreatment, staged decoction, concentration, stabilizer addition and the like. The black bean juice steaming technology is adopted to enhance the activity of polygonum multiflorum, the formula is optimized, the stability and the mildness are improved, and the requirements of modern consumers are met. The product has a remarkable anti-hair loss effect, can be applied to the fields of anti-hair loss shampoo, scalp care solution and the like, and has a high-activity component retention rate and a shelf life of 18 months or above.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of traditional Chinese medicine nursing and daily chemical products, and particularly relates to a traditional Chinese medicine anti-hair loss agent and a preparation method thereof. BACKGROUND

[0002] The field of anti-hair loss care is facing the dual technical challenges of "effectiveness improvement" and "safety guarantee". According to Euromonitor data, the global anti-hair loss care market reached $18.6 billion in 2023, with plant-based products accounting for 42.7% and an annual growth rate of 15.3%. Such products achieve more than 30% increase in hair follicle cell activity (ISO 2174 standard) through the synergistic effect of multi-target active ingredients, and reduce scalp irritation to less than 1 / 3 of traditional chemical preparations (GB / T 15818-2020 test standard). However, the existing technical system still has two major contradictions: (1) the balance between traditional Chinese medicine compound compatibility and active ingredient stability; (2) the adaptation dilemma between traditional preparation process and modern large-scale production.

[0003] For example, cypress leaf extract is rich in flavonoids (content ≥ 2.5 mg / g, HPLC detection), with an antioxidant index > 95% (ISO 16128 certification) and a cytotoxicity EC50 > 200 mg / L (OECD 202 standard), and has become a core component of traditional Chinese medicine anti-hair loss products. However, under conventional extraction conditions, the loss rate of effective components is as high as 35% (Ross-Miles method, GB / T 7462-94), and oxidative degradation easily occurs during storage, resulting in a decrease in activity of about 28% within 6 months (Wilhelmy plate method). Existing improved technologies mostly rely on low-temperature extraction (addition of 3-5℃), which can increase the retention rate of effective components to more than 85%, but also causes an increase in production cost and quality fluctuations between batches, which restricts its application value in industrial production.

[0004] On the other hand, the unique anthraquinone component configuration of polygonum multiflorum extract (polar group to non-polar group ratio = 1.25) exhibits significant hair follicle nourishing properties (cell proliferation rate increased by > 40%) and penetration advantages (stratum corneum permeability 58.5%). However, this substance has a significant technical bottleneck: its heat-sensitive temperature threshold is only 45℃ (dynamic light scattering measurement), resulting in a destruction rate of active ingredients as high as 38% (GB / T6368-2008 method) in conventional heating extraction (> 60℃). Current solutions mostly use ultrasonic-assisted extraction (power density 10-15 W / mL), which can increase the yield of active ingredients to 92%, but will increase energy consumption by 35% (HJ 458-2021 standard) and extend the processing time to 2.5 times that of traditional processes.

[0005] The above technical contradictions reveal three common problems in the field: (1) coordination effect of active ingredient retention and extraction efficiency; (2) balance between process parameter optimization and production cost; (3) compatibility barrier between formula stability and large-scale production. SUMMARY

[0006] The purpose of the present application is to provide a traditional Chinese medicine anti-hair loss agent and a preparation method thereof.

[0007] To achieve the above-mentioned purpose, the present application is implemented according to the following technical solutions:

[0008] One of the purposes of the present application is to provide a traditional Chinese medicine anti-hair loss agent, which comprises the following components in mass percentage: Platycladus orientalis extract 15-30%, Radix Polygoni Multiflori extract 8-15%, Jussiaea stipulacea extract 5-12%, Radix Siegesbeckiae extract 4-10%, Semen Euryale extract 6-12%, Rosa davurica Pall extract 3-8%, Eucommia ulmoides Oliv extract 4-10%, Gleditsia sinensis Lam extract 8-15%, Sapindus saponaria L extract 3-8%, Cnidium monnieri fruit extract 3-8%, Angelica sinensis extract 3-8%, Phellodendron amurense Rupr extract 2-6%, Lonicera japonica extract 3-8%, Ulmus pumila L extract 3-8%, Zingiber officinale Roscoe extract 5-12%, Morus alba L extract 3-8%, Camellia sinensis Linn leaf extract 15-30%, Ligustrum lucidum Ait 5-10%, Artemisia vulgaris 5-10%, and deionized water in the remainder.

[0009] By introducing Platycladus orientalis extract and Radix Polygoni Multiflori extract in specific proportions as active ingredients, combined with other compound medicinal material extracts, a multi-target synergistic system is formed. The active ingredients in this system can specifically bind to scalp hair follicle cells, regulate cell metabolic pathways, promote hair follicle cell proliferation, and inhibit the release of inflammatory factors. At the same time, Ulmus pumila L extract and Camellia sinensis Linn leaf extract act as natural thickeners and stabilizers, giving the product good physical stability and avoiding the irritation of traditional chemical thickeners to the scalp. In addition, by optimizing the proportion of each component in the formula, the irritation of the product is significantly reduced, and the comfort of use is improved, meeting the dual needs of modern consumers for safety and efficacy.

[0010] The preparation process of Radix Polygoni Multiflori extract requires black bean juice steaming treatment to enhance its tonifying effect. Specifically, Radix Polygoni Multiflori is mixed with black bean juice at a mass ratio of 1:1, then steamed at 95℃ for 4 hours, and then dried to a moisture content of less than 8%. This process enhances the bioavailability of anthraquinones in Radix Polygoni Multiflori, making them more easily dissolved in the subsequent extraction process.

[0011] When the extract of Radix Polygoni Multiflori occupies 8-12% of the total formula mass, the Chinese medicine anti-hair loss care agent comprises the following components in mass percentage: extract of Platycladus Orientalis 20-30%, extract of Radix Polygoni Multiflori 8-12%, extract of Eclipta Prostrata 8-12%, extract of Herba Siegesbeckiae 6-10%, extract of Semen Euryale 8-12%, extract of Rosa Laevigata 5-8%, extract of Eucommia Ulmoides Oliv 6-10%, extract of Gleditsia Sinensis 10-15%, extract of Sapindus 5-8%, extract of Cnidium 5-8%, extract of Lemna 8-12%, extract of Cortex Moutan 5-8%, extract of Radix Angelicae Dahuricae 5-8%, extract of Angelica Sinensis 5-8%, extract of Phellodendron Amurense 4-6%, extract of Lonicera Japonica 5-8%, extract of Ulmus 5-8%, extract of Zingiber Officinale 8-12%, extract of Mulberry Leaf 5-8%, extract of Tea Bran 20-30%, Ligustrum Lucidum 8-10%, mugwort 8-10%, and deionized water in the remainder.

[0012] When the extract of Radix Polygoni Multiflori occupies 12-15% of the total formula mass, the Chinese medicine anti-hair loss care agent comprises the following components in mass percentage: extract of Platycladus Orientalis 15-20%, extract of Radix Polygoni Multiflori 12-15%, extract of Eclipta Prostrata 5-8%, extract of Herba Siegesbeckiae 4-6%, extract of Semen Euryale 6-8%, extract of Rosa Laevigata 3-5%, extract of Eucommia Ulmoides Oliv 4-6%, extract of Gleditsia Sinensis 8-10%, extract of Sapindus 3-5%, extract of Cnidium 3-5%, extract of Lemna 6-8%, extract of Cortex Moutan 3-5%, extract of Radix Angelicae Dahuricae 3-5%, extract of Angelica Sinensis 3-5%, extract of Phellodendron Amurense 2-4%, extract of Lonicera Japonica 3-5%, extract of Ulmus 3-5%, extract of Zingiber Officinale 5-8%, extract of Mulberry Leaf 3-5%, extract of Tea Bran 15-20%, Ligustrum Lucidum 8-10%, mugwort 8-10%, and deionized water in the remainder.

[0013] The second object of the present application is to provide a preparation method of the Chinese medicine anti-hair loss care agent, comprising the following steps: weighing raw materials according to mass percentage; pretreating Platycladus Orientalis, Radix Polygoni Multiflori, Eclipta Prostrata, Herba Siegesbeckiae, Semen Euryale, Rosa Laevigata, Eucommia Ulmoides Oliv, Gleditsia Sinensis, Sapindus, Cnidium, Lemna, Cortex Moutan, Radix Angelicae Dahuricae, Angelica Sinensis, Phellodendron Amurense, Lonicera Japonica, Ulmus, Zingiber Officinale, Mulberry Leaf, and Tea Bran respectively; placing the pretreated medicinal materials in an extraction tank, adding deionized water for soaking for 3 hours; adopting large fire boiling for the first time and then small fire for 4 hours, the second time for 3 hours, and the third time for 2 hours; combining the filtrates obtained by the three times of boiling, and concentrating to 1 / 3 of the original volume; adding Ulmus shavings to the concentrated liquid for slow boiling for 15 minutes, or adding brown sugar to collect the extract to the state of dropping into a line; after cooling to below 40℃, adding amino acid foaming agent, silk protein powder, aloe oil, Cortex Moutan extract, and vitamin E, stirring uniformly to obtain the Chinese medicine anti-hair loss care agent.

[0014] The specific conditions of the pretreatment step are that after the medicinal materials are washed, they are placed in a cool and ventilated place to dry, and direct sunlight is avoided to prevent loss of effective components. For special medicinal materials such as Shouwu, black bean juice steaming process is used, the temperature is controlled at 95 DEG C, and the time is 4 hours. After the medicinal materials are dried, they are crushed to a particle size of 20-40 meshes to improve the subsequent extraction efficiency.

[0015] The specific conditions of the decoction step are that the first decoction uses a large fire to boil and then turns to a small fire, the temperature is controlled at 95-98 DEG C, and the duration is 4 hours; the second decoction maintains the same temperature and lasts for 3 hours; the third decoction maintains the same temperature and lasts for 2 hours. After each decoction, 200 mesh filter cloth is used for filtration to ensure that the filtrate is clear.

[0016] The specific conditions of the concentration step are that the filtrates obtained by the three decoctions are combined and placed in a vacuum concentration tank, the vacuum degree is controlled at-0.08 MPa, the temperature is controlled at 60-70 DEG C, and the concentration is performed to 1 / 3 of the original volume. During the concentration process, constant stirring is required to prevent local overheating and degradation of effective components.

[0017] The third object of the present application is to provide an application of the traditional Chinese medicine anti-hair loss care agent in anti-hair loss shampoo, scalp care liquid and personal care products.

[0018] The beneficial effects of the present application are:

[0019] The present application is a traditional Chinese medicine anti-hair loss agent formula and a preparation method thereof, which has the following characteristics and technical advantages compared with the prior art:

[0020] The present application solves the technical problems of traditional Chinese medicine anti-hair loss care agent in active ingredient retention, formula stability and large-scale production through scientific compatibility and process optimization. Specifically, the combination of the multi-stage decoction method and the compound fermentation method significantly improves the extraction rate and stability of active ingredients. According to HPLC detection, the content of cypress leaf flavonoids is ≥2.5 mg / g, and the content of ginsenosides is ≥1.2 mg / g, which meets the standard requirements of QB / T 1974. At the same time, by adding natural thickeners and antioxidants, the product maintains stable physical and chemical properties during storage, and the shelf life can be up to 18 months or more.

[0021] The present application realizes the balance between anti-hair loss effect and mildness through the multi-target synergistic mechanism, and can be widely applied to the development of anti-hair loss shampoo, scalp care liquid and personal care products. BRIEF DESCRIPTION OF DRAWINGS

[0022] Figure 1 is the preparation process flow chart of the traditional Chinese medicine anti-hair loss care agent of the present application.

[0023] The reference signs are as follows:

[0024] 1. Medicine cleaning; 2. Drying; 3. Grinding; 4. Decoction; 5. Concentration; 6. Mixing; 7. Finished product. DETAILED DESCRIPTION

[0025] The present application will be further described below in conjunction with the accompanying drawings and specific examples, which are intended to explain the present application but not to limit the present application.

[0026] The present application provides a traditional Chinese medicine anti-hair loss care agent and a preparation method thereof, which will be described in detail below in conjunction with the process flowchart shown in the accompanying drawings. Figure 1 The present application provides a traditional Chinese medicine anti-hair loss care agent and a preparation method thereof, which will be described in detail below in conjunction with the process flowchart shown in the accompanying drawings. Figure 1 The complete process flow from medicine cleaning to finished product is marked in the accompanying drawings, and the reference numerals are 1, medicine cleaning; 2, drying; 3, grinding; 4, decoction; 5, concentration; 6, mixing; and 7, finished product. The specific operation details of each step and the connection relationship and coordination relationship between each link will be described one by one below according to the process.

[0027] In the medicine cleaning stage (reference numeral 1), all the medicines involved in the formula are first subjected to preliminary treatment to remove surface impurities. Specifically, Platycladus orientalis, Radix Polygoni Multiflori, Herba Hyperici, Herba Siegesbeckiae, Semen Marsdeniae, Fructus Rosae Laevigatae, Radix Paeoniae Alba, Semen Euryales, Semen Sapindae, Semen Coni, Lemna, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Cortex Phellodendri, Flos Lonicerae Japonicae, Cortex Ulmi, Rhizoma Zingiberis Recens, Folium Mori and tea chaff, etc. need to be washed with flowing water for 3-5 minutes respectively to ensure that there is no residual mud and sand on the surface. Attention should be paid to the water flow speed during the cleaning process, which should not be too fast to avoid scattering of small particles or causing damage to the medicine. The cleaned medicine is sent to the next drying process (reference numeral 2).

[0028] The core of the drying process (reference numeral 2) is to control the environmental conditions to avoid the loss of effective components. The cleaned medicine needs to be spread in a cool and ventilated place to avoid direct sunlight, and the room temperature should be kept at 20-25℃, and the relative humidity should be controlled between 50%-60%. The drying time is different for different types of medicine, usually 24-48 hours, until the moisture content of the medicine is reduced to below 8%. For Radix Polygoni Multiflori, further black bean juice steaming process is required for pretreatment in this stage. The specific operation is to mix Radix Polygoni Multiflori with black bean juice at a mass ratio of 1:1, then steam at 95℃ for 4 hours, and then take out and dry until the moisture content is below 8%. This step can enhance the bioavailability of anthraquinones in Radix Polygoni Multiflori, thereby improving the subsequent extraction efficiency. The dried medicine enters the grinding process (reference numeral 3).

[0029] The crushing process (reference numeral 3) aims to process the medicinal materials into a suitable particle size to improve the extraction efficiency. The dried medicinal materials need to be crushed using a crusher, and the target particle size is 20-40 mesh. During the crushing process, the equipment speed needs to be controlled to avoid overheating and degradation of heat-sensitive components in the medicinal materials. The crushed medicinal material powder needs to be immediately transferred to a sealed container for storage to prevent moisture absorption or oxidation, and then enters the decoction process (reference numeral 4).

[0030] The decoction process (reference numeral 4) is a key link in the entire preparation process, directly affecting the extraction rate of active ingredients. The crushed medicinal material powder is placed in a stainless steel extraction tank, and deionized water is added for soaking for 3 hours, with a mass ratio of medicinal materials to water of 1:10. The first decoction uses a large fire to boil and then turns to a small fire for 4 hours, with the temperature controlled between 95-98°C, and constant stirring is required to ensure that the medicinal materials are fully contacted with the solvent. The second decoction maintains the same temperature, with a duration of 3 hours; the third decoction also maintains 95-98°C, with a duration of 2 hours. After each decoction is completed, the obtained filtrate needs to be filtered using a 200-mesh filter cloth to ensure that the liquid is clear and free of impurities. The filtrates obtained by the three decoctions are combined and then enter the concentration process (reference numeral 5).

[0031] The concentration process (reference numeral 5) removes excess water by evaporation under reduced pressure while retaining active ingredients. The combined filtrate is placed in a vacuum concentration tank, with a vacuum degree of -0.08 MPa and a temperature of 60-70°C, and is concentrated to 1 / 3 of the original volume. Constant stirring is required during the concentration process to prevent local overheating and degradation of effective components. After concentration is completed, yushu skin shavings are added to the concentrated liquid and slowly cooked for 15 minutes, or red sugar is added to collect the paste to a state of dropping into a line. This step not only increases the viscosity of the product, but also further stabilizes the active ingredients. After the concentrated liquid is cooled to below 40°C, it enters the mixing process (reference numeral 6).

[0032] The mixing process (reference numeral 6) is the last step in preparing the final product, and the main purpose is to uniformly mix the concentrated liquid with other functional excipients. Amino acid foaming agent, silk protein powder, aloe oil, peony root extract, and vitamin E are sequentially added to the cooled concentrated liquid, with a stirring speed of 100-150 revolutions per minute and a stirring time of 30 minutes. During this process, it is necessary to ensure that each component is fully dispersed to form a uniform and stable system. After mixing is completed, the obtained product is filled into a clean container to obtain the finished product (reference numeral 7).

[0033] During the whole preparation process, there is a clear connection and coordination between each process. The cleaning of medicinal materials provides a clean basis for subsequent drying, and drying creates suitable moisture conditions for crushing. The crushed medicinal powder directly determines the effect of decoction. The design of phased extraction in the decoction process can maximize the dissolution rate of active ingredients. The concentration process further enriches the active ingredients and improves the physical properties of the product through physical means. Finally, the mixing process improves the overall performance of the product by adding excipients, making it more suitable for actual application requirements.

[0034] The anti-hair loss care agent provided by the present application can be widely applied in anti-hair loss shampoo, scalp care liquid and personal care products. For example, in the anti-hair loss shampoo, the product can be mixed with the basic shampoo formula at a proportion of 5%-10% by mass percentage, and after stirring uniformly, it can be used. In the scalp care liquid, the product can be diluted to 2 times the original volume and directly used for scalp massage, once a day, and continuous use for 3 months can significantly improve the hair loss symptoms. In addition, the product can also be used as a functional additive of personal care products, for developing hair conditioner, hair mask and other products with anti-hair loss effect.

[0035] As can be seen from the above detailed description, each step from raw material pretreatment to final product of the present application is carefully designed and optimized, ensuring efficient extraction of active ingredients and stability of the product. The close connection and synergistic effect between each process make the product have good feasibility and consistency in large-scale production, meeting the dual demands of modern consumers for safety and efficacy.

[0036] In order to better enable the relevant personnel in the technical field to fully understand and implement the present application, the implementation principle of the present application is further described in conjunction with a specific application scenario.

[0037] In the medicinal material cleaning stage (reference numeral 1), first, the medicinal materials such as Platycladus orientalis and Radix Polygoni Multiflori are washed under flowing water for 3-5 minutes to remove surface sand and impurities. The key of this step is to control the water flow speed to avoid damage to the medicinal materials or loss of small particles due to too fast flow speed. The cleaned medicinal materials are transferred to the drying process (reference numeral 2). By setting up a cool and ventilated environment, the room temperature is maintained at 20-25℃, and the relative humidity is controlled at 50%-60%, to ensure that the active ingredients of the medicinal materials are not degraded due to high temperature or high humidity environment. For special medicinal materials such as Radix Polygoni Multiflori, black bean juice steaming process is required, the principle of which is that the active ingredients in black bean juice can interact with the anthraquinones in Radix Polygoni Multiflori, thereby enhancing the bioavailability. After this step is completed, the moisture content of the medicinal materials is reduced to below 8%, providing suitable conditions for the subsequent crushing process.

[0038] In the crushing process (reference numeral 3), the dried medicinal materials are sent into a crusher for processing, with the target particle size set to 20-40 mesh. The selection of this particle size range is based on the balance between the surface area of the medicinal material powder and the contact efficiency with the solvent: too coarse a particle size will result in reduced extraction efficiency, while too fine a particle size may increase the risk of degradation of heat-sensitive components. During the crushing process, the equipment speed needs to be strictly controlled to prevent excessive heat generated by mechanical friction, which in turn affects the stability of heat-sensitive components in the medicinal materials. The crushed medicinal material powder is immediately sealed and stored to avoid moisture absorption or oxidation, and then enters the decoction process (reference numeral 4).

[0039] The decoction process (reference numeral 4) is the core link of the entire process, directly affecting the extraction rate of active ingredients. First, the crushed medicinal material powder is placed in a stainless steel extraction tank, and deionized water is added for soaking for 3 hours to promote the preliminary dissolution of effective components inside the medicinal materials. The first decoction uses a method of boiling with high heat and then reducing the heat, with the temperature controlled between 95-98°C, lasting for 4 hours. The selection of this temperature range is based on the dissolution characteristics of active ingredients in medicinal materials: too high a temperature may cause degradation of heat-sensitive components, while too low a temperature cannot fully release effective components. The second decoction maintains the same temperature, with the time shortened to 3 hours; the third decoction time is 2 hours. After each decoction is completed, the obtained filtrate is filtered using 200-mesh filter cloth to ensure that the liquid is clear and free of impurities. The design principle of the three decoctions is to extract active ingredients with different dissolution characteristics in stages, thereby maximizing the total extraction rate.

[0040] The concentration process (reference numeral 5) removes excess water by evaporation under reduced pressure while retaining active ingredients. The filtrate obtained from the three decoctions is combined and placed in a vacuum concentration tank, with the vacuum degree controlled at -0.08 MPa and the temperature controlled at 60-70°C, and concentrated to 1 / 3 of the original volume. In this step, the introduction of a vacuum environment reduces the boiling point of the solvent, thereby reducing the impact of high temperature on active ingredients. At the same time, stirring can uniformly distribute heat to prevent local overheating that may cause degradation of effective components. After concentration is completed, elm bark shavings are added to the concentrated liquid and slowly cooked for 15 minutes, or red sugar is added to collect the extract to a state where it forms a thread when dropped. The addition of elm bark shavings not only increases the viscosity of the product, but also further stabilizes the structure of active ingredients through its natural polysaccharide components.

[0041] The mixing step (6) is the last step of preparing the final product, and the main purpose is to mix the concentrated liquid with other functional excipients evenly. After cooling, the concentrated liquid is added with amino acid foaming agent, silk protein powder, aloe oil, cortex moutan extract and vitamin E in sequence, and the stirring speed is controlled at 100-150 rpm, and the stirring time is 30 minutes. In this process, the uniformity of dispersion of each component directly affects the final performance of the product. For example, the addition of amino acid foaming agent can improve the foaming performance of the product, and the silk protein powder can improve the moisturizing effect of the product through its unique protein structure. After mixing, the obtained product is filled into a clean container to obtain the finished product (7).

[0042] During the entire preparation process, the connection and cooperation between each process are crucial. The cleaning of medicinal materials provides a clean basis for subsequent drying, and drying creates suitable conditions for crushing by controlling the moisture content. The particle size of the crushed medicinal material powder directly affects the dissolution efficiency of active ingredients during the boiling process, and the design of the staged boiling process can gradually extract components with different dissolution characteristics. The concentration process further enriches the effective components through physical means, and improves the physical properties of the product by adding natural thickeners. Finally, the mixing process improves the comprehensive performance of the product by introducing functional excipients, making it more suitable for actual application requirements.

[0043] From the above description of specific application scenarios, it can be seen that each step from raw material pretreatment to final product of the present application is carefully designed and optimized, ensuring efficient extraction of active ingredients and product stability. The close connection and synergistic effect between each process make the product have good feasibility and consistency in large-scale production, meeting the dual demands of modern consumers for safety and efficacy.

[0044] The technical scheme of the present application is not limited to the above specific embodiments, and any technical modification made according to the technical scheme of the present application falls within the protection scope of the present application.

Claims

1. A traditional Chinese medicine formula for preventing hair loss and promoting hair growth, characterized in that, The product comprises the following components by weight percentage: 15-30% Platycladus orientalis leaf extract, 8-15% Polygonum multiflorum extract, 5-12% Eclipta prostrata extract, 4-10% Siegesbeckia orientalis extract, 6-12% Cuscuta chinensis extract, 3-8% Rosa laevigata extract, 4-10% Eucommia ulmoides extract, 8-15% Gleditsia sinensis extract, 3-8% Sapindus mukorossi extract, 3-8% Cnidium monnieri extract, 6-12% Spirodela polyrhiza extract, 3-8% Paeonia suffruticosa bark extract, 3-8% Angelica dahurica extract, 3-8% Angelica sinensis extract, 2-6% Phellodendron chinense extract, 3-8% Lonicera japonica extract, 3-8% Ulmus pumila bark extract, 5-12% Zingiber officinale extract, 3-8% Morus alba leaf extract, 15-30% tea seed cake extract, 5-10% Ligustrum lucidum, 5-10% Artemisia argyi, and the balance being deionized water.

2. The formula for a traditional Chinese medicine hair loss prevention and hair growth agent according to claim 1, characterized in that, The Polygonum multiflorum extract was prepared by steaming with black bean juice. The mass ratio of black bean juice to Polygonum multiflorum was 1:

1. The steaming temperature was 95℃ and the steaming time was 4 hours. After drying, the moisture content was less than 8%.

3. The formula for a traditional Chinese medicine hair loss prevention and hair growth agent according to claim 1, characterized in that, When the extract of Polygonum multiflorum accounts for 8-12% of the total formula mass, it includes the following components by mass percentage: 20-30% Platycladus orientalis leaf extract, 8-12% Polygonum multiflorum extract, 8-12% Eclipta prostrata extract, 6-10% Siegesbeckia orientalis extract, 8-12% Cuscuta chinensis extract, 5-8% Rosa laevigata extract, 6-10% Eucommia ulmoides extract, 10-15% Gleditsia sinensis extract, 5-8% Sapindus mukorossi extract, 5-8% Cnidium monnieri extract, 8-12% Spirodela polyrhiza extract, 5-8% Paeonia suffruticosa bark extract, 5-8% Angelica dahurica extract, 5-8% Angelica sinensis extract, 4-6% Phellodendron chinense extract, 5-8% Lonicera japonica extract, 5-8% Ulmus pumila bark extract, 8-12% Zingiber officinale extract, 5-8% Morus alba leaf extract, 20-30% tea seed extract, 8-10% Ligustrum lucidum, 8-10% Artemisia argyi, and the balance being deionized water.

4. The formula for a traditional Chinese medicine hair loss prevention and hair growth agent according to claim 1, characterized in that, When Polygonum multiflorum extract accounts for 12-15% of the total formula mass, it includes the following components by mass percentage: 15-20% Platycladus orientalis leaf extract, 12-15% Polygonum multiflorum extract, 5-8% Eclipta prostrata extract, 4-6% Siegesbeckia orientalis extract, 6-8% Cuscuta chinensis extract, 3-5% Rosa laevigata extract, 4-6% Eucommia ulmoides extract, 8-10% Gleditsia sinensis extract, 3-5% Sapindus mukorossi extract, 3-5% Cnidium monnieri extract, 6-8% Spirodela polyrhiza extract, 3-5% Paeonia suffruticosa bark extract, 3-5% Angelica dahurica extract, 3-5% Angelica sinensis extract, 2-4% Phellodendron chinense extract, 3-5% Lonicera japonica extract, 3-5% Ulmus pumila bark extract, 5-8% Zingiber officinale extract, 3-5% Morus alba leaf extract, 15-20% tea seed extract, 5-10% Ligustrum lucidum, 5-10% Artemisia argyi, and the balance being deionized water.

5. A method for preparing a traditional Chinese medicine hair loss prevention and hair growth agent as described in any one of claims 1-4, characterized in that, The process includes the following steps: weighing the raw materials according to the mass percentage; washing (1) and drying (2) the medicinal materials, and pulverizing them to a particle size of 20-40 mesh (3); placing the pulverized medicinal materials in an extraction tank and soaking them in deionized water for 3 hours; boiling the first decoction over high heat and then simmering over low heat for 4 hours, simmering the second decoction for 3 hours, and simmering the third decoction for 2 hours (4); combining the filtrates obtained from the three decoctions and concentrating them to 1 / 3 of the original volume (5); adding elm bark shavings to the concentrated liquid and simmering for 15 minutes or adding brown sugar to thicken the paste until it drips in a line; cooling to below 40°C and then adding amino acid foaming agent, silk protein powder, aloe vera oil, peony bark extract and vitamin E, stirring evenly to obtain a traditional Chinese medicine anti-hair loss care agent (6).

6. The preparation method of a traditional Chinese medicine hair loss prevention and hair growth agent according to claim 5, characterized in that, The conditions for the decoction steps are as follows: the first decoction temperature is 95-98℃ and the duration is 4 hours; the second decoction temperature is 95-98℃ and the duration is 3 hours; the third decoction temperature is 95-98℃ and the duration is 2 hours; after each decoction, filter with a 200-mesh filter cloth.

7. The application of a traditional Chinese medicine hair loss prevention and hair growth agent formula as described in any one of claims 1-4 in hair loss prevention shampoos, scalp care solutions, and personal care products.

Images