High-oxygen ischemia preconditioning device

Abstract

The high-oxygen ischemia pre-adaptation device comprises a high-oxygen module and an ischemia pre-adaptation module, the high-oxygen module comprises an oxygen bottle, an oxygen electromagnetic valve and a nasal catheter, the oxygen bottle is fixedly connected with the input end of the nasal catheter through the oxygen electromagnetic valve, and the other end of the nasal catheter is used for a user to inhale oxygen; the ischemia pre-adaptation module comprises an air pump and an ischemia pre-adaptation assembly, the ischemia pre-adaptation assembly comprises a circuit control board, a high-pressure electromagnetic valve, a low-pressure electromagnetic valve, a pressure reducing valve and a cuff connecting pipe, the input end of the high-pressure electromagnetic valve is fixedly connected with the output end of the air pump, and the output end of the high-pressure electromagnetic valve is fixedly connected with the input end of the pressure reducing valve; the output end of the pressure reducing valve is fixedly connected with the input end of the low-pressure electromagnetic valve, and a cuff connecting pipe is arranged between the pressure reducing valve and the low-pressure electromagnetic valve and used for being connected with a cuff. The high-oxygen ischemia preconditioning device provided by the invention can better treat the user, and can shorten the treatment cycle, so that the treatment effect reaches an expected ideal level.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment, and in particular to a hyperoxic ischemic preconditioning device. Background Art

[0002] Ischemic preconditioning (IPC) refers to the process by which a brief, non-lethal ischemic stimulus primes tissues or organs to tolerate subsequent, longer-term ischemic injury. This mechanism was first discovered in 1986 by Murry et al. in a dog experiment. Specifically, a brief ischemic stimulus (e.g., four cycles of 5-minute ischemia followed by reperfusion) can reduce the size of myocardial infarction caused by subsequent prolonged ischemia.

[0003] Ischemic preconditioning is an endogenous protective mechanism activated by mild ischemic stress, enabling the heart or other tissues to better cope with subsequent similar or more severe ischemic stress. This protective mechanism involves multiple intracellular signaling pathways, including activation of protein kinase C and opening of mitochondrial ATP-sensitive potassium channels. Furthermore, ischemic preconditioning can reduce cell apoptosis after ischemia-reperfusion injury.

[0004] The patent with publication number CN219271943U discloses an air pump type ischemic preconditioning device, which includes an air pump and an ischemic preconditioning component. The ischemic preconditioning component includes a high-pressure solenoid valve, a low-pressure solenoid valve, a pressure reducing valve, a timer, a time relay, a relay and a cuff. The high-pressure solenoid valve, the pressure reducing valve, the low-pressure solenoid valve, the time relay, the timer and the relay are all fixed on the air pump. One end of the high-pressure solenoid valve is connected to the air outlet of the air pump, and the other end is connected to one end of the pressure reducing valve. The other end of the pressure reducing valve is connected to the low-pressure solenoid valve, and the cuff is connected between the pressure reducing valve and the low-pressure solenoid valve. Although the device has a simple structure, low price, easy to popularize and durable, the treatment cycle of the air pump type ischemic preconditioning device is long and the effect is slow, resulting in its treatment effect failing to reach the expected ideal level. Summary of the Invention

[0005] To this end, the present application provides a hyperoxic ischemic preconditioning device to solve the problems of long treatment cycle and slow effect of air pump type ischemic preconditioning devices in the prior art.

[0006] In order to achieve the above objectives, this application provides the following technical solutions:

[0007] A hyperoxia-ischemia preconditioning device comprises a hyperoxia module and an ischemia preconditioning module, wherein the hyperoxia module comprises an oxygen cylinder, an oxygen solenoid valve, and a nasal cannula, wherein the output end of the oxygen cylinder is fixedly connected to the air circuit input end of the oxygen solenoid valve, the air circuit output end of the oxygen solenoid valve is fixedly connected to the input end of the nasal cannula, and the other end of the nasal cannula is used for a user to inhale oxygen;

[0008] The ischemic preconditioning module includes an air pump and an ischemic preconditioning component, and the ischemic preconditioning component includes a circuit control board, a high-pressure solenoid valve, a low-pressure solenoid valve, a pressure reducing valve and a cuff connecting pipe. The circuit control board, the high-pressure solenoid valve, the low-pressure solenoid valve and the pressure reducing valve are all fixedly arranged on the top of the air pump, the air circuit input end of the high-pressure solenoid valve is fixedly connected to the output end of the air pump, the air circuit output end of the high-pressure solenoid valve is fixedly connected to the air circuit input end of the pressure reducing valve, the air circuit output end of the pressure reducing valve is fixedly connected to the air circuit input end of the low-pressure solenoid valve, and a cuff connecting pipe is provided between the pressure reducing valve and the low-pressure solenoid valve, and the cuff connecting pipe is used to connect a cuff;

[0009] Among them, the circuit control board is integrated with a central control module, a cycle timing module and a circuit switching module, the output end of the cycle timing module is electrically connected to the input end of the central control module, the output end of the central control module is electrically connected to the input end of the circuit switching module, one output end of the circuit switching module is electrically connected to the high-pressure solenoid valve, and the other output end of the circuit switching module is electrically connected to the low-pressure solenoid valve and the oxygen solenoid valve, and the low-pressure solenoid valve and the oxygen solenoid valve are connected in parallel.

[0010] Preferably, the high oxygen module also includes an oxygen meter and a buoy-type oxygen inhaler, the input end of the oxygen meter is fixedly connected to the output end of the oxygen cylinder, and the output end of the oxygen meter is fixedly connected to the air path input end of the oxygen solenoid valve via the buoy-type oxygen inhaler.

[0011] Preferably, the ischemic preconditioning module further comprises a manual countdown switch, which is fixedly arranged on the top of the air pump and electrically connected to the high-pressure solenoid valve, the low-pressure solenoid valve and the oxygen solenoid valve respectively.

[0012] Preferably, the duration of the manual countdown switch setting is 48 minutes.

[0013] Preferably, the circuit switching module is an automatic single-pole double-throw switch.

[0014] Preferably, the cycle time of the cycle timing module is once every five minutes.

[0015] Preferably, the air pump is an oil-free air compressor or a discarded refrigerator compressor.

[0016] Preferably, the nasal cannula can be replaced by an oxygen mask.

[0017] Compared with the prior art, this application has at least the following beneficial effects:

[0018] The present application provides a hyperoxia-ischemia preconditioning device, including a hyperoxia module and an ischemia preconditioning module. The hyperoxia module includes an oxygen cylinder, an oxygen solenoid valve and a nasal catheter. The output end of the oxygen cylinder is fixedly connected to the air circuit input end of the oxygen solenoid valve, the air circuit output end of the oxygen solenoid valve is fixedly connected to the input end of the nasal catheter, and the other end of the nasal catheter is used for the user to inhale oxygen; the ischemia preconditioning module includes an air pump and an ischemia preconditioning component. The ischemia preconditioning component includes a circuit control board, a high-pressure solenoid valve, a low-pressure solenoid valve, a pressure reducing valve and a cuff connecting pipe. The air circuit input end of the high-pressure solenoid valve is fixedly connected to the output end of the air pump, the air circuit output end of the high-pressure solenoid valve is fixedly connected to the air circuit input end of the pressure reducing valve, the air circuit output end of the pressure reducing valve is fixedly connected to the air circuit input end of the low-pressure solenoid valve, and a cuff connecting pipe is provided between the pressure reducing valve and the low-pressure solenoid valve, and the cuff connecting pipe is used to connect the cuff. The hyperoxia-ischemia pre-adaptation device provided in this application can shut off oxygen at the beginning of hypoxia in ischemia pre-adaptation, and supply high oxygen through the nose at the end of hypoxia, so as to match the intermittent high and low oxygen of RLad, thereby better treating the user, shortening the treatment cycle, and making the treatment effect reach the expected ideal level. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] To more intuitively illustrate the prior art and the present application, exemplary drawings are provided below. It should be understood that the specific shapes and structures shown in the drawings should not generally be considered as limiting conditions for implementing the present application; for example, based on the technical concepts disclosed in this application and the exemplary drawings, those skilled in the art are capable of easily making routine adjustments or further optimizations to the addition / reduction / attribution division, specific shapes, positional relationships, connection methods, dimensional ratios, etc. of certain units (components).

[0020] Figure 1 A schematic structural diagram of a hyperoxic ischemic preconditioning device provided in this application;

[0021] Figure 2 A schematic diagram of the gas circuit connection of a hyperoxic ischemic preconditioning device provided in this application;

[0022] Figure 3 This is a circuit schematic diagram of a hyperoxic ischemic preconditioning device provided in this application.

[0023] Description of reference numerals:

[0024] 1. Hyperoxia module; 101. Oxygen cylinder; 102. Oxygen solenoid valve; 103. Nasal cannula; 2. Ischemic preconditioning module; 201. Air pump; 202. Circuit control board; 203. High-pressure solenoid valve; 204. Low-pressure solenoid valve; 205. Pressure reducing valve; 206. Cuff connecting tube. DETAILED DESCRIPTION

[0025] The present application will be further described below in detail through specific embodiments in conjunction with the accompanying drawings.

[0026] In the description of this application: unless otherwise specified, the meaning of "plurality" is two or more. The terms "first", "second", "third", etc. in this application are intended to distinguish the objects referred to and do not have any special meaning in terms of technical connotation (for example, they should not be understood as emphasizing the importance or order, etc.). Expressions such as "including", "comprising", "having", etc. also mean "not limited to" (certain units, components, materials, steps, etc.).

[0027] The terms such as "upper", "lower", "left", "right", "middle", etc. cited in this application are usually used to indicate the general relative position relationship for the convenience of intuitive understanding by referring to the drawings, and are not absolute limitations on the position relationship in the actual product.

[0028] The RLad intermittent high-low oxygen theory involves exposing the body to low oxygen levels between 11% and 21%. After five minutes, the body is exposed to high oxygen levels between 21% and 28%, and this cycle repeats. A Howard Hughes Medical Institute study stated that "oxygen is crucial for intervening in the aging process. Limiting oxygen concentration not only improves physical fitness but can also extend lifespan by 50%." Because low oxygen levels activate cellular potential, while high oxygen levels can relieve and repair it, the body maintains a youthful state by repeatedly switching between high and low oxygen levels. This cycle typically lasts approximately 50 minutes.

[0029] See also Figure 1 and Figure 2 The present application provides a hyperoxia-ischemia preconditioning device based on the RLad intermittent hyperoxia-hypoxia theory, including a hyperoxia module 1 and an ischemia preconditioning module 2. The hyperoxia module 1 includes an oxygen cylinder 101, an oxygen solenoid valve 102 and a nasal catheter 103. The output end of the oxygen cylinder 101 is fixedly connected to the air circuit input end of the oxygen solenoid valve 102, and the air circuit output end of the oxygen solenoid valve 102 is fixedly connected to the input end of the nasal catheter 103. The other end of the nasal catheter 103 is used for the user to inhale oxygen.

[0030] The ischemic preconditioning module 2 includes an air pump 201 and an ischemic preconditioning component. The ischemic preconditioning component includes a circuit control board 202, a high-pressure solenoid valve 203, a low-pressure solenoid valve 204, a pressure reducing valve 205 and a cuff connecting tube 206. The circuit control board 202, the high-pressure solenoid valve 203, the low-pressure solenoid valve 204 and the pressure reducing valve 205 are all fixedly arranged on the top of the air pump 201. The air circuit input end of the high-pressure solenoid valve 203 is fixedly connected to the output end of the air pump 201, the air circuit output end of the high-pressure solenoid valve 203 is fixedly connected to the air circuit input end of the pressure reducing valve 205, the air circuit output end of the pressure reducing valve 205 is fixedly connected to the air circuit input end of the low-pressure solenoid valve 204, and a cuff connecting tube 206 is arranged between the pressure reducing valve 205 and the low-pressure solenoid valve 204. The two cuff connecting tubes 206 are used to connect two cuffs.

[0031] See also Figure 3 The circuit control board 202 integrates a central control module, a cycle timing module and a circuit switching module. The output end of the cycle timing module is electrically connected to the input end of the central control module, and the output end of the central control module is electrically connected to the input end of the circuit switching module. One output end of the circuit switching module is electrically connected to the high-pressure solenoid valve 203, and the other output end of the circuit switching module is electrically connected to the low-pressure solenoid valve 204 and the oxygen solenoid valve 102. The low-pressure solenoid valve 204 and the oxygen solenoid valve 102 are connected in parallel.

[0032] In a hyperoxia-ischemia pre-adaptation device provided in the present application, the hyperoxia module 1 also includes an oxygen meter and a buoy-type oxygen inhaler. The input end of the oxygen meter is fixedly connected to the output end of the oxygen cylinder 101, and the output end of the oxygen meter is fixedly connected to the air circuit input end of the oxygen solenoid valve 102 via the buoy-type oxygen inhaler; the buoy-type oxygen inhaler is used to ensure that the oxygen concentration is maintained at an appropriate and safe level to prevent health problems or safety accidents caused by insufficient or excessive oxygen.

[0033] In the hyperoxia-ischemia preconditioning device provided in the present application, the ischemia preconditioning module 2 also includes a manual countdown switch, which is fixedly arranged on the top of the air pump 201 and is electrically connected to the high-pressure solenoid valve 203, the low-pressure solenoid valve 204 and the oxygen solenoid valve 102 respectively; the manual countdown switch is set to a time length of 48 minutes.

[0034] In the hyperoxic ischemic preconditioning device provided by the present application, the circuit switching module is an automatic single-pole double-throw switch, and the cycle time of the cycle timing module is once every five minutes.

[0035] In the hyperoxic ischemic preconditioning device provided in the present application, the air pump 201 is an oil-free air compressor or a discarded refrigerator compressor, which is beneficial to environmental protection.

[0036] In the hyperoxia-ischemia preconditioning device provided in the present application, the nasal catheter 103 can be replaced with an oxygen mask, which is more convenient for users to use.

[0037] The present application provides a hyperoxic ischemic preconditioning device, the working principle of which is as follows: the hyperoxic ischemic preconditioning device is started by controlling the circuit control board 202 (or a manual countdown switch), and after starting, power is supplied to the high-pressure solenoid valve 203, and the high-pressure solenoid valve 203 starts to work, thereby causing the first cuff and the second cuff to clamp the user's arm, and at the same time, the cycle timing module starts timing; after the timing time is reached (generally five minutes), the circuit control board 202 controls the high-pressure solenoid valve 203 to lose power, and the high-pressure solenoid valve 203 stops working. At the same time, the low-pressure solenoid valve 204 and the oxygen solenoid valve 102 are energized and work. After the low-pressure solenoid valve 204 is energized, air is deflated, and the first and second cuffs are relieved. After the oxygen solenoid valve 102 is energized, nasal oxygen inhalation is started. After the cycle timing time is reached, the high-pressure solenoid valve 203 continues to be energized, and the above process is continued to cycle until 5 processes are cycled (which can be adaptively adjusted according to the user's physical condition).

[0038] The present application provides a hyperoxia-ischemia preconditioning device that combines hyperoxia and ischemia preconditioning technologies to enhance the body's tolerance to ischemic injury. The device consists of a hyperoxia module 1 and an ischemia preconditioning module 2. The hyperoxia module 1 intermittently provides high-concentration oxygen to the user via an oxygen cylinder 101, an oxygen solenoid valve 102, and a nasal cannula 103, thereby improving oxygenation levels. The ischemia preconditioning module 2 simulates an ischemic state via an air pump 201, a pressure reducing valve 205, a high-pressure solenoid valve 203, a low-pressure solenoid valve 204, and a cuff, thereby promoting adaptive changes in blood vessels. The circuit control board 202 integrates a central control module, a cycle timing module, and a circuit switching module to automatically control the alternating cycles of hyperoxia and ischemia to achieve a protective effect on the body. Through the combined regulation of this device, the body's tolerance to ischemia can be effectively improved, with broad clinical application potential and low cost.

[0039] The hyperoxia-ischemia pre-adaptation device provided in this application is based on the RLad intermittent high and low oxygen theory. It shuts off oxygen at the beginning of the hypoxia stage of ischemic pre-adaptation, and supplies high oxygen through the nose at the end of the hypoxia stage to match the RLad intermittent high and low oxygen, thereby better treating the user and shortening the treatment cycle, so that the treatment effect reaches the expected ideal level.

[0040] The technical features of the above embodiments can be combined arbitrarily (as long as there is no contradiction in the combination of these technical features). In order to make the description concise, not all possible combinations of the technical features in the above embodiments are described; these embodiments that are not explicitly written should also be considered to be within the scope of this specification.

Claims

1. A hyperoxic ischemic preconditioning device, characterized in that: It includes a hyperoxia module and an ischemic preconditioning module. The hyperoxia module includes an oxygen cylinder, an oxygen solenoid valve, and a nasal catheter. The output end of the oxygen cylinder is fixedly connected to the air circuit input end of the oxygen solenoid valve, and the air circuit output end of the oxygen solenoid valve is fixedly connected to the input end of the nasal catheter. The other end of the nasal catheter is used for the user to inhale oxygen. The ischemic preconditioning module includes an air pump and an ischemic preconditioning component, and the ischemic preconditioning component includes a circuit control board, a high-pressure solenoid valve, a low-pressure solenoid valve, a pressure reducing valve and a cuff connecting pipe. The circuit control board, the high-pressure solenoid valve, the low-pressure solenoid valve and the pressure reducing valve are all fixedly arranged on the top of the air pump, the air circuit input end of the high-pressure solenoid valve is fixedly connected to the output end of the air pump, the air circuit output end of the high-pressure solenoid valve is fixedly connected to the air circuit input end of the pressure reducing valve, the air circuit output end of the pressure reducing valve is fixedly connected to the air circuit input end of the low-pressure solenoid valve, and a cuff connecting pipe is provided between the pressure reducing valve and the low-pressure solenoid valve, and the cuff connecting pipe is used to connect a cuff; Among them, the circuit control board is integrated with a central control module, a cycle timing module and a circuit switching module, the output end of the cycle timing module is electrically connected to the input end of the central control module, the output end of the central control module is electrically connected to the input end of the circuit switching module, one output end of the circuit switching module is electrically connected to the high-pressure solenoid valve, and the other output end of the circuit switching module is electrically connected to the low-pressure solenoid valve and the oxygen solenoid valve, and the low-pressure solenoid valve and the oxygen solenoid valve are connected in parallel.

2. The hyperoxic ischemic preconditioning device according to claim 1, characterized in that: The high oxygen module also includes an oxygen meter and a buoy-type oxygen inhaler. The input end of the oxygen meter is fixedly connected to the output end of the oxygen cylinder. The output end of the oxygen meter is fixedly connected to the air path input end of the oxygen solenoid valve via the buoy-type oxygen inhaler.

3. The hyperoxic ischemic preconditioning device according to claim 1, characterized in that: The ischemic preconditioning module further includes a manual countdown switch, which is fixedly arranged on the top of the air pump and electrically connected to the high-pressure solenoid valve, the low-pressure solenoid valve and the oxygen solenoid valve respectively.

4. The hyperoxic ischemic preconditioning device according to claim 3, characterized in that: The duration of the manual countdown switch setting is 48 minutes.

5. The hyperoxic ischemic preconditioning device according to claim 1, characterized in that: The circuit switching module is an automatic single-pole double-throw switch.

6. The hyperoxic ischemic preconditioning device according to claim 1, characterized in that: The cycle time of the cycle timing module is once every five minutes.

7. The hyperoxic ischemic preconditioning device according to claim 1, characterized in that: The air pump is an oil-free air compressor or a discarded refrigerator compressor.

8. The hyperoxic ischemic preconditioning device according to claim 1, characterized in that: The nasal cannula can be replaced by an oxygen mask.

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