Airway clearance equipment control method based on lung electrical impedance imaging system

Abstract

The invention discloses an airway clearance equipment control method based on a lung electrical impedance imaging system. The airway clearance equipment control method comprises the following steps that S1, threshold values of monitoring parameters in airway clearance equipment are set; s2, real-time numerical values of the physiological parameters are obtained through a lung electrical impedance imaging system; s3, calculating the real-time numerical values of the physiological parameters obtained in the step S2, comparing the real-time numerical values with the threshold values of the monitoring parameters set in the step S1, and adjusting the operation parameters of the airway clearance equipment according to the comparison result; and S4, circularly executing the steps S2 and S3. According to the invention, automatic control based on objective data is realized, and subjectivity caused by human judgment is avoided.

Description

Technical Field

[0001] The present invention belongs to the field of medical equipment control and relates to the control of airway clearing equipment, in particular to an airway clearing equipment control method based on a pulmonary electrical impedance imaging system. Background Art

[0002] Airway clearance technology based on Electrical Impedance Tomography (EIT) was developed to address the common problem of atelectasis in mechanically ventilated patients in the intensive care unit (ICU), particularly those undergoing surgery. Atelectasis is a major cause of inadequate oxygenation, respiratory failure, and prolonged mechanical ventilation. Traditional airway clearance methods include physical therapy and incentive-based breathing trainers (IS), but these methods have limitations, such as low patient comfort, poor compliance, and difficulty in real-time evaluation of effectiveness.

[0003] The OPEP (Oscillatory Positive Expiratory Pressure) device is a non-pharmacological airway clearance tool that helps loosen sputum and maintain airway patency by generating positive pressure and oscillation during exhalation. Although studies have shown that the OPEP device can enhance sputum clearance and temporarily increase lung capacity, its effectiveness in lung recruitment in postoperative patients remains unclear. Furthermore, there is a lack of effective clinical monitoring and evaluation methods for the specific mechanism of action and effectiveness of the OPEP device in enhancing lung recruitment and improving gas distribution.

[0004] EIT technology provides a non-invasive, real-time monitoring method for changes in lung ventilation distribution, including regional changes such as recruitment and overinflation. Combining EIT monitoring with OPEP therapy can more accurately assess airway clearance effectiveness, optimize device control strategies, improve patient oxygenation levels, reduce complications, and ultimately improve clinical outcomes. Summary of the Invention

[0005] This invention provides a control method for airway clearance equipment based on a pulmonary electrical impedance imaging system. This control method uses EIT to monitor and obtain relevant pulmonary ventilation parameters in real time. Combined with an analysis algorithm, it automatically identifies the ventilation mode type and then implements the corresponding OPEP parameter adjustment scheme, achieving intelligent and personalized respiratory therapy.

[0006] The technical solution of the present invention is specifically: a method for controlling an airway clearance device based on a pulmonary electrical impedance imaging system, comprising the following steps:

[0007] Step S1: setting a threshold value of a monitoring parameter in an airway clearance device;

[0008] Step S2: obtaining real-time values ​​of physiological parameters through the pulmonary electrical impedance imaging system;

[0009] Step S3: Calculate the real-time value of the physiological parameter obtained in step S2 and compare it with the threshold of the monitoring parameter set in step S1, and adjust the operating parameters of the airway clearing device according to the comparison result;

[0010] Step S4: Execute steps S2 and S3 in a loop.

[0011] Furthermore, the monitoring parameters in step S1 include setting the inter-lung swing ratio (PR), setting the global heterogeneity index (GI), the regional ventilation delay (RVD) and the ventilation coefficient of variation (COV);

[0012] The thresholds for each monitoring parameter are as follows:

[0013] The threshold of interpulmonary swing ratio (PR) was set at 15%;

[0014] The threshold of the global inhomogeneity index (GI) was set to 0.5;

[0015] The threshold for regional ventilation delay (RVD) was set at 20%;

[0016] The threshold of the coefficient of variation (COV) of ventilation was set at 40%.

[0017] Furthermore, the physiological parameters in step S2 specifically include: gas redistribution volume (Vtpendelluft), tidal volume (VT), global inhomogeneity index (GI) and regional ventilation delay (RVD).

[0018] Furthermore, the monitoring parameter value of the inter-lung swing ratio is calculated based on the two physiological parameter values ​​of gas redistribution volume (Vtpendelluft) and tidal volume (VT).

[0019] Furthermore, the specific calculation formula is: inter-pulmonary swing ratio (PR) = (gas redistribution volume (Vtpendelluft) / tidal volume (VT))×100%.

[0020] Furthermore, the step S3 is specifically as follows:

[0021] Adjust the rate and pressure of the airway clearance device when the interpulmonary sway ratio (PR) is below the threshold, the global inhomogeneity index (GI) is below the threshold and below 0.4, the regional ventilation delay (RVD) is above the threshold and above 25%, and the coefficient of ventilation variation (COV) is below the threshold; or

[0022] When the interpulmonary sway ratio (PR) is above the threshold and is greater than 20%, the global heterogeneity index (GI) is below the threshold, the regional ventilation delay (RVD) is below the threshold, and the coefficient of ventilation variation (COV) is below the threshold, increase the positive end-expiratory pressure (PEEP) of the airway clearance device and extend the device usage time; or

[0023] When the interpulmonary sway ratio (PR) is below the threshold, the global inhomogeneity index (GI) is below the threshold, the regional ventilation delay (RVD) is below the threshold, and the coefficient of ventilation variation (COV) is below the threshold and less than 20%, reduce the positive end-expiratory pressure (PEEP) of the airway clearance device and shorten the device usage time; or

[0024] Adjust the frequency of positive end-expiratory pressure (PEEP) of the airway clearance device when the interpulmonary swing ratio (PR) is above the threshold and is greater than 25%, the global heterogeneity index (GI) is below the threshold, the regional ventilation delay (RVD) is below the threshold, and the coefficient of ventilation variation (COV) is above the threshold and is greater than 50%; or

[0025] When the interpulmonary sway ratio (PR) is below the threshold, the global inhomogeneity index (GI) is below the threshold, the regional ventilation delay (RVD) is below the threshold, and the coefficient of ventilation variation (COV) is above the threshold and is greater than 45%, adjust the airway clearance device frequency to 8 Hz, the pressure to 20 cmH2O, the inspiration-expiration ratio to 1:2, and the duration to 30 minutes; or

[0026] When the interpulmonary swing ratio (PR) is below the threshold, the global heterogeneity index (GI) is above the threshold and above 0.6, the regional ventilation delay (RVD) is above the threshold and above 30%, and the coefficient of ventilation variation (COV) is below the threshold, the frequency of the airway clearance device is adjusted to 10 to 15 Hz, the pressure is set to 15 to 18 cmH2O, the positive end-expiratory pressure (PEEP) is 6 to 8 cmH2O, and the duration is set to 15 to 30 minutes.

[0027] Furthermore, the operating parameters include the frequency of the airway clearing device, the pressure of the airway clearing device, the operating time of the airway clearing device and the PEEP pressure.

[0028] Furthermore, it also includes:

[0029] Step S5: When SpO2 decreases by more than 4%, respiratory rate increases by more than 30%, and heart rate changes by more than 20%, the execution of steps S2 and S3 is terminated, and a termination message is issued.

[0030] Furthermore, the step S4 further includes: monitoring the operating status of the airway clearing device;

[0031] The three parameters of lung recruitment, gas distribution, and periodic alveolar collapse are obtained through the pulmonary electrical impedance imaging system;

[0032] The above three parameter data are used to calculate the increase in lung ventilation, improvement in oxygenation, and reduction in atelectasis, thereby monitoring whether the airway clearance device is operating normally.

[0033] Furthermore, when ΔFEV1.1>10%, it is determined that the airway clearance device is operating normally, and the process returns to step S2;

[0034] When ΔFEV1.1≤10%, Δoverdistension is determined;

[0035] When Δoverdistension>10%, it is determined that the airway clearance device is not functioning properly and an alarm message is issued;

[0036] When Δoverdistension≤10%, the operation time of the airway clearing device is increased, and the process returns to step S2.

[0037] The technical effects of the present invention are mainly reflected in:

[0038] 1. It realizes automated control based on objective data, avoiding the subjectivity brought by human judgment;

[0039] 2. A dual monitoring mechanism has been established, which can not only accurately identify the ventilation mode but also detect potential risks in a timely manner. The present invention uses an EIT monitoring system to obtain and process lung ventilation-related data. The EIT system collects two types of key parameters in real time: the first type includes the inter-lung swing ratio (PR), the global inhomogeneity index (GI), the regional ventilation delay (RVD), and the ventilation coefficient of variation (COV). This set of parameters is used to automatically identify the current ventilation mode type and set the initial operating parameters of the OPEP device accordingly. The second type includes the degree of lung recruitment, gas distribution, and periodic alveolar collapse data, which are used to monitor the safety status of the OPEP device in real time during operation.

[0040] 3. A complete closed-loop control system is formed to ensure the accuracy and safety of the treatment process.

[0041] the term:

[0042] Gas redistribution volume (Vtpendelluft) refers to the volume of gas redistributed between lung regions, reflecting the degree of ventilation unevenness between different lung regions. The larger the value, the more significant the difference in ventilation distribution between lung regions.

[0043] Tidal volume (VT) refers to the volume of gas inhaled or exhaled during each breath. EIT can monitor local and global tidal volume changes in real time to evaluate ventilation effectiveness.

[0044] The Global Inhomogeneity Index (GI) is used to quantify the degree of uneven ventilation distribution throughout the lungs. The index value typically ranges from 0 to 1, with larger values ​​indicating more uneven ventilation distribution.

[0045] Regional ventilation delay (RVD) reflects the difference in ventilation timing between different lung regions and is used to assess ventilation synchronization between lung regions. Larger RVD values ​​indicate significant regional ventilation time differences. BRIEF DESCRIPTION OF THE DRAWINGS

[0046] Figure 1 Schematic diagram for setting thresholds for monitoring parameters in airway clearance equipment.

[0047] Figure 2 To clarify the use of equipment results comparison chart. DETAILED DESCRIPTION

[0048] Hereinafter, with reference to the accompanying drawings, preferred embodiments of the present disclosure will be described in detail. In the following description, identical symbols are assigned to identical components, and repeated descriptions are omitted. In addition, the accompanying drawings are only schematic diagrams, and the ratio of the dimensions of the components to each other or the shapes of the components, etc. may be different from the actual ones. It should be noted that the terms "including" and "having" in the present disclosure and any variations thereof, such as a process, method, system, product or device that includes or has a series of steps or units, are not necessarily limited to those steps or units clearly listed, but may include or have other steps or units that are not clearly listed or that are inherent to these processes, methods, products or devices. All methods described in the present disclosure may be performed in any suitable order, unless otherwise indicated herein or clearly contradicted by the context.

[0049] Example 1

[0050] This embodiment is aimed at cases with simple airway obstruction characteristics, and adopts the technical solution of the present invention to achieve good results. The specific implementation steps are as follows:

[0051] Step S1: Setting the thresholds of the monitoring parameters in the airway clearance device. The specific thresholds are:

[0052] The threshold of interpulmonary swing ratio (PR) was set at 15%;

[0053] The threshold of the global inhomogeneity index (GI) was set to 0.5;

[0054] The threshold for regional ventilation delay (RVD) was set at 20%;

[0055] The threshold of the coefficient of variation (COV) of ventilation was set at 40%.

[0056] See also Figure 1 , Figure 1The paper demonstrates the threshold values ​​for four key parameters in the EIT monitoring system. These include: the coefficient of variation (COV) threshold, set at 40%, representing the overall degree of ventilation variability; the global inhomogeneity index (GI) threshold, set at 0.5, reflecting the uniformity of lung ventilation distribution; the interpulmonary swing ratio (PR) threshold, set at 15%, measuring the redistribution of gas between different lung regions; and the regional ventilation delay (RVD) threshold, set at 20%, representing the critical value for the difference in ventilation time between different regions. Together, these threshold parameters constitute the benchmark for assessing lung ventilation status.

[0057] Step S2: The real-time values ​​of physiological parameters are obtained through the pulmonary electrical impedance imaging system. The real-time values ​​are analyzed and calculated, specifically:

[0058] The lung swing ratio (PR) value is lower than the threshold;

[0059] The global inhomogeneity index (GI) value is lower than the threshold;

[0060] The regional ventilation delay (RVD) value is higher than the threshold;

[0061] The coefficient of variation (COV) of ventilation is higher than the threshold.

[0062] Step S3: Calculate the real-time value of the physiological parameter obtained in step S2 and compare it with the threshold of the monitoring parameter set in step S1. Adjust the operating parameters of the airway clearing device according to the comparison result. The specific operating parameters are set as follows:

[0063] 1) When the RVD value is within the range of 25%-35%, the OPEP frequency is increased to 10 Hz, and the other operating parameters remain unchanged;

[0064] 2) When the RVD value is within the range of 35%-45%, the OPEP frequency is increased to 12 Hz, and the other operating parameters remain unchanged;

[0065] 3) When the RVD value is greater than 45%, the OPEP frequency is increased to 15 Hz, and the other operating parameters remain unchanged;

[0066] 4) When the GI value is within the range of 0.3-0.4, the OPEP pressure is increased to 15 cmH2O, and the other operating parameters remain unchanged;

[0067] 5) When the GI value is within the range of 0.2-0.3, the OPEP pressure is increased to 18 cmH2O, and the other operating parameters remain unchanged;

[0068] 6) When the GI value is less than 0.2, the OPEP pressure is increased to 20 cmH2O, and the other operating parameters remain unchanged;

[0069] After each parameter adjustment, the fixed duration is maintained at 20 minutes.

[0070] When SpO2 decreases by more than 4%, respiratory rate increases by more than 30%, and heart rate changes by more than 20%, step S2 and step S3 are terminated, and a termination message is issued.

[0071] Example 2

[0072] This embodiment is aimed at cases with alveolar collapse characteristics, and adopts the technical solution of the present invention to implement it, and achieves good results. The specific implementation steps are as follows:

[0073] Step S1: Setting the thresholds of the monitoring parameters in the airway clearance device. The specific thresholds are:

[0074] The threshold of interpulmonary swing ratio (PR) was set at 15%;

[0075] The threshold of the global inhomogeneity index (GI) was set to 0.5;

[0076] The threshold for regional ventilation delay (RVD) was set at 20%;

[0077] The threshold of the coefficient of variation (COV) of ventilation was set at 40%.

[0078] Step S2: The real-time values ​​of physiological parameters are obtained through the pulmonary electrical impedance imaging system. The real-time values ​​are analyzed and calculated, specifically:

[0079] The lung swing ratio (PR) value is higher than the threshold;

[0080] The global inhomogeneity index (GI) value is below the threshold;

[0081] The regional ventilation delay (RVD) value was below the threshold;

[0082] The coefficient of variation (COV) of ventilation was below the threshold.

[0083] Step S3: Calculate the real-time value of the physiological parameter obtained in step S2 and compare it with the threshold of the monitoring parameter set in step S1. Adjust the operating parameters of the airway clearing device according to the comparison result. The specific operating parameters are set as follows:

[0084] Increase the PEEP pressure and extend the OPEP running time, while keeping the other parameters unchanged.

[0085] When SpO2 decreases by more than 4%, respiratory rate increases by more than 30%, and heart rate changes by more than 20%, step S2 and step S3 are terminated, and a termination message is issued.

[0086] Example 3

[0087] This embodiment is aimed at cases with over-expansion characteristics, and adopts the technical solution of the present invention to achieve good results. The specific implementation steps are as follows:

[0088] Step S1: Setting the thresholds of the monitoring parameters in the airway clearance device. The specific thresholds are:

[0089] The threshold of interpulmonary swing ratio (PR) was set at 15%;

[0090] The threshold of the global inhomogeneity index (GI) was set to 0.5;

[0091] The threshold for regional ventilation delay (RVD) was set at 20%;

[0092] The threshold of the coefficient of variation (COV) of ventilation was set at 40%.

[0093] Step S2: The real-time values ​​of physiological parameters are obtained through the pulmonary electrical impedance imaging system. The real-time values ​​are analyzed and calculated, specifically:

[0094] The lung swing ratio (PR) value is below the threshold;

[0095] The global inhomogeneity index (GI) value is below the threshold;

[0096] The regional ventilation delay (RVD) value was below the threshold;

[0097] The coefficient of variation (COV) of ventilation was below the threshold.

[0098] Step S3: Calculate the real-time value of the physiological parameter obtained in step S2 and compare it with the threshold of the monitoring parameter set in step S1. Adjust the operating parameters of the airway clearing device according to the comparison result. The specific operating parameters are set as follows:

[0099] Reduce the PEEP pressure and shorten the OPEP running time, while keeping other parameter settings unchanged.

[0100] When SpO2 decreases by more than 4%, respiratory rate increases by more than 30%, and heart rate changes by more than 20%, step S2 and step S3 are terminated, and a termination message is issued.

[0101] Example 4

[0102] This embodiment is aimed at cases with secretion retention characteristics, and adopts the technical solution of the present invention to achieve good results. The specific implementation steps are as follows:

[0103] Step S1: Setting the thresholds of the monitoring parameters in the airway clearance device. The specific thresholds are:

[0104] The threshold of interpulmonary swing ratio (PR) was set at 15%;

[0105] The threshold of the global inhomogeneity index (GI) was set to 0.5;

[0106] The threshold for regional ventilation delay (RVD) was set at 20%;

[0107] The threshold of the coefficient of variation (COV) of ventilation was set at 40%.

[0108] Step S2: The real-time values ​​of physiological parameters are obtained through the pulmonary electrical impedance imaging system. The real-time values ​​are analyzed and calculated, specifically:

[0109] The lung swing ratio (PR) value was 85%;

[0110] The global inhomogeneity index (GI) value is 0.45;

[0111] The regional ventilation delay (RVD) value was 25%;

[0112] The coefficient of variation (COV) of ventilation was 55%.

[0113] Step S3: Calculate the real-time value of the physiological parameter obtained in step S2 and compare it with the threshold of the monitoring parameter set in step S1. Adjust the operating parameters of the airway clearing device according to the comparison result. The specific operating parameters are set as follows:

[0114] The frequency of OPEP was set at 15 Hz;

[0115] The OPEP pressure was set at 20 cmH2O;

[0116] The running time is set to 30 minutes.

[0117] Through real-time adjustment of operating parameters, PR increased to 90%, GI decreased to 0.4, RVD decreased to 20%, and COV decreased to 45%, indicating that the adjustment plan achieved the expected effect.

[0118] When SpO2 decreases by more than 4%, respiratory rate increases by more than 30%, and heart rate changes by more than 20%, step S2 and step S3 are terminated, and a termination message is issued.

[0119] Example 5

[0120] This embodiment is aimed at cases with respiratory muscle fatigue characteristics, and adopts the technical solution of the present invention to achieve good results. The specific implementation steps are as follows:

[0121] Step S1: Setting the thresholds of the monitoring parameters in the airway clearance device. The specific thresholds are:

[0122] The threshold of interpulmonary swing ratio (PR) was set at 15%;

[0123] The threshold of the global inhomogeneity index (GI) was set to 0.5;

[0124] The threshold for regional ventilation delay (RVD) was set at 20%;

[0125] The threshold of the coefficient of variation (COV) of ventilation was set at 40%.

[0126] Step S2: The real-time values ​​of physiological parameters are obtained through the pulmonary electrical impedance imaging system. The real-time values ​​are analyzed and calculated, specifically:

[0127] The lung swing ratio (PR) value is below the threshold;

[0128] The global inhomogeneity index (GI) value is below the threshold;

[0129] The regional ventilation delay (RVD) value was below the threshold;

[0130] The coefficient of variation (COV) of ventilation is above the threshold.

[0131] Step S3: Calculate the real-time value of the physiological parameter obtained in step S2 and compare it with the threshold of the monitoring parameter set in step S1. Adjust the operating parameters of the airway clearing device according to the comparison result. The specific operating parameters are set as follows:

[0132] The frequency of OPEP was set at 8 Hz;

[0133] The OPEP pressure was set at 20 cmH2O;

[0134] The running time is set to 20 minutes;

[0135] The breathing ratio was adjusted to 1:2.

[0136] When SpO2 decreases by more than 4%, respiratory rate increases by more than 30%, and heart rate changes by more than 20%, step S2 and step S3 are terminated, and a termination message is issued.

[0137] Example 6

[0138] This embodiment is aimed at cases with uneven ventilation characteristics, and adopts the technical solution of the present invention to achieve good results. The specific implementation steps are as follows:

[0139] Step S1: Setting the thresholds of the monitoring parameters in the airway clearance device. The specific thresholds are:

[0140] The threshold of interpulmonary swing ratio (PR) was set at 15%;

[0141] The threshold of the global inhomogeneity index (GI) was set to 0.5;

[0142] The threshold for regional ventilation delay (RVD) was set at 20%;

[0143] The threshold of the coefficient of variation (COV) of ventilation was set at 40%.

[0144] Step S2: The real-time values ​​of physiological parameters are obtained through the pulmonary electrical impedance imaging system. The real-time values ​​are analyzed and calculated, specifically:

[0145] The lung swing ratio (PR) value was 55%;

[0146] The global inhomogeneity index (GI) value is 0.65;

[0147] The regional ventilation delay (RVD) value was 35%;

[0148] The coefficient of variation (COV) of ventilation was 45%.

[0149] Step S3: Calculate the real-time values ​​of the physiological parameters obtained in step S2 and compare them with the thresholds of the monitoring parameters set in step S1. Adjust the operating parameters of the airway clearing device based on the comparison results. The specific operating parameters are set using a three-step progressive adjustment process:

[0150] first step:

[0151] The frequency of OPEP was set to 15 Hz;

[0152] The OPEP pressure was set at 18 cmH2O;

[0153] The PEEP pressure was set at 6 cmH2O;

[0154] The running time is set to 20 minutes;

[0155] Step 2:

[0156] The frequency of OPEP was set at 12 Hz;

[0157] The OPEP pressure was set at 18 cmH2O;

[0158] The PEEP pressure was set at 8 cmH2O;

[0159] The running time is set to 15 minutes;

[0160] Step 3:

[0161] The frequency of OPEP was set to 10 Hz;

[0162] The OPEP pressure was set at 15 cmH2O;

[0163] The PEEP pressure was set at 8 cmH2O;

[0164] The run time is set to 15 minutes.

[0165] See also Figure 2 , which compares the changes in various parameters before and after the use of the airway clearing device. By comparing the bar graphs, one can intuitively see the effect of using the control method of the airway clearing device of this embodiment, including the changes in four key indicators: the coefficient of ventilation variation (COV), global inhomogeneity index (GI), lung swing ratio (PR), and regional ventilation delay (RVD) before and after treatment. The green column represents the parameter value after treatment, and the red column represents the parameter value before treatment. This comparison can clearly evaluate the effectiveness of the device control method.

[0166] When SpO2 decreases by more than 4%, respiratory rate increases by more than 30%, and heart rate changes by more than 20%, step S2 and step S3 are terminated, and a termination message is issued.

[0167] Example 7

[0168] This embodiment, based on the first to sixth embodiments, further includes monitoring the operating status of the airway clearing device, specifically:

[0169] The three parameters of lung recruitment, gas distribution, and periodic alveolar collapse are obtained through the pulmonary electrical impedance imaging system;

[0170] The above three parameter data are used to calculate the increase in lung ventilation, improvement in oxygenation, and reduction in atelectasis, thereby monitoring whether the airway clearance device is operating normally.

[0171] When ΔFEV1.1>10%, it is determined that the airway clearance device is operating normally, and the process returns to step S2;

[0172] When ΔFEV1.1≤10%, Δoverdistension is determined;

[0173] When Δoverdistension>10%, it is determined that the airway clearance device is not functioning properly and an alarm message is issued;

[0174] When Δoverdistension≤10%, the operation time of the airway clearing device is increased, and the process returns to step S2.

[0175] These examples demonstrate that the system can accurately determine ventilation mode type based on EIT monitoring data and implement corresponding parameter adjustments. Furthermore, by continuously monitoring the effects of these adjustments, the effectiveness and safety of the treatment plan are ensured. This automated adjustment based on objective data avoids potential errors caused by human judgment and improves system reliability and accuracy.

[0176] Although the present invention has been specifically described above in conjunction with the accompanying drawings and embodiments, it will be understood that the above description does not limit the present invention in any form. Those skilled in the art may modify and change the present invention as needed without departing from the spirit and scope of the present invention, and these modifications and changes all fall within the scope of the present invention.

Claims

1. A method for controlling an airway clearance device based on a pulmonary electrical impedance imaging system, characterized in that: The steps include: Step S1: setting a threshold value of a monitoring parameter in an airway clearance device; Step S2: obtaining real-time values ​​of physiological parameters through the pulmonary electrical impedance imaging system; Step S3: Calculate the real-time value of the physiological parameter obtained in step S2 and compare it with the threshold of the monitoring parameter set in step S1, and adjust the operating parameters of the airway clearing device according to the comparison result; Step S4: Execute steps S2 and S3 in a loop.

2. The control method according to claim 1, wherein: The monitoring parameters in step S1 include setting the inter-lung swing ratio (PR), setting the global inhomogeneity index (GI), the regional ventilation delay (RVD) and the ventilation coefficient of variation (COV); The thresholds for each monitoring parameter are as follows: The threshold of interpulmonary swing ratio (PR) was set at 15%; The threshold of the global inhomogeneity index (GI) was set to 0.5; The threshold for regional ventilation delay (RVD) was set at 20%; The threshold of the coefficient of variation (COV) of ventilation was set at 40%.

3. The control method according to claim 1, wherein: The physiological parameters in step S2 specifically include: gas redistribution volume (Vtpendelluft), tidal volume (VT), global inhomogeneity index (GI) and regional ventilation delay (RVD).

4. The control method according to claim 3, wherein: The monitoring parameter value of the inter-lung swing ratio is calculated based on the two physiological parameter values ​​of gas redistribution volume (Vtpendelluft) and tidal volume (VT).

5. The control method according to claim 4, characterized in that: The specific calculation formula is: interpulmonary swing ratio (PR) = (gas redistribution volume (Vtpendelluft) / tidal volume (VT)) × 100%.

6. The control method according to claim 2, wherein: The step S3 is specifically as follows: Adjust the rate and pressure of the airway clearance device when the interpulmonary sway ratio (PR) is below the threshold, the global inhomogeneity index (GI) is below the threshold and below 0.4, the regional ventilation delay (RVD) is above the threshold and above 25%, and the coefficient of ventilation variation (COV) is below the threshold; or When the interpulmonary sway ratio (PR) is above the threshold and is greater than 20%, the global heterogeneity index (GI) is below the threshold, the regional ventilation delay (RVD) is below the threshold, and the coefficient of ventilation variation (COV) is below the threshold, increase the positive end-expiratory pressure (PEEP) of the airway clearance device and extend the device usage time; or When the interpulmonary sway ratio (PR) is below the threshold, the global inhomogeneity index (GI) is below the threshold, the regional ventilation delay (RVD) is below the threshold, and the coefficient of ventilation variation (COV) is below the threshold and less than 20%, reduce the positive end-expiratory pressure (PEEP) of the airway clearance device and shorten the device usage time; or Adjust the frequency of positive end-expiratory pressure (PEEP) of the airway clearance device when the interpulmonary swing ratio (PR) is above the threshold and is greater than 25%, the global heterogeneity index (GI) is below the threshold, the regional ventilation delay (RVD) is below the threshold, and the coefficient of ventilation variation (COV) is above the threshold and is greater than 50%; or When the interpulmonary sway ratio (PR) is below the threshold, the global inhomogeneity index (GI) is below the threshold, the regional ventilation delay (RVD) is below the threshold, and the coefficient of ventilation variation (COV) is above the threshold and is greater than 45%, adjust the airway clearance device frequency to 8 Hz, the pressure to 20 cmH2O, the inspiration-expiration ratio to 1:2, and the duration to 30 minutes; or When the interpulmonary swing ratio (PR) is below the threshold, the global heterogeneity index (GI) is above the threshold and above 0.6, the regional ventilation delay (RVD) is above the threshold and above 30%, and the coefficient of ventilation variation (COV) is below the threshold, the frequency of the airway clearance device is adjusted to 10 to 15 Hz, the pressure is set to 15 to 18 cmH2O, the positive end-expiratory pressure (PEEP) is 6 to 8 cmH2O, and the duration is set to 15 to 30 minutes.

7. The control method according to claim 1, wherein: The operating parameters include the frequency of the airway clearing device, the pressure of the airway clearing device, the operating time of the airway clearing device and the PEEP pressure.

8. The control method according to claim 1, wherein: Also includes: Step S5: When SpO2 decreases by more than 4%, respiratory rate increases by more than 30%, and heart rate changes by more than 20%, the execution of steps S2 and S3 is terminated, and a termination message is issued.

9. The control method according to claim 1, wherein: The step S4 further includes: monitoring the operating status of the airway clearing device; The three parameters of lung recruitment, gas distribution, and periodic alveolar collapse are obtained through the pulmonary electrical impedance imaging system; The above three parameter data are used to calculate the increase in lung ventilation, improvement in oxygenation, and reduction in atelectasis, thereby monitoring whether the airway clearance device is operating normally.

10. The control method according to claim 9, characterized in that: When ΔFEV1.1>10%, it is determined that the airway clearance device is operating normally, and the process returns to step S2; When ΔFEV1.1≤10%, Δoverdistension is determined; When Δoverdistension>10%, it is determined that the airway clearance device is not functioning properly and an alarm message is issued; When Δoverdistension≤10%, the operation time of the airway clearing device is increased, and the process returns to step S2.

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