Tear detection device

By integrating the design of components such as threaded sleeves, sealing covers and air bags, the operational process of MMP-9 antibody testing is simplified, the problem of multiple transfers of the test fluid is solved, and the detection efficiency and result accuracy are improved.

CN120668911APending Publication Date: 2025-09-19THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIV
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202510809575.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-17
Publication Date
2025-09-19

AI Technical Summary

Technical Problem

The existing MMP-9 antibody detection process is complicated and the detection fluid needs to be transferred multiple times, which increases workload, reduces efficiency and affects the accuracy of results.

Method used

A tear MMP-9 detector is designed, which integrates components such as a threaded sleeve, a sealing cover, and an air bag to realize the integrated operations of saline instillation, test fluid collection, and delivery to the tear MMP-9 test reagent card, simplifying the process and improving the sealing.

Benefits of technology

Simplify the operating process, reduce the difficulty of operation, improve detection efficiency and result accuracy, and reduce the contamination and loss of detection fluid.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN120668911A_ABST
    Figure CN120668911A_ABST
Patent Text Reader

Abstract

The invention relates to the technical field of medical apparatus and instruments, and discloses a tear detection device which comprises a tear mmp-9 detector, a detection cavity is formed in the tear mmp-9 detector, a tear mmp-9 detection reagent card is arranged in the detection cavity, a conveying hose is connected to the top of a threaded sleeve, a sealing cover communicated with the conveying hose is rotatably mounted at the bottom of the threaded sleeve, and the threaded sleeve is connected with a tear mp-9 detection reagent card. An air bag is mounted on the tear mmm-9 detector, and the air bag is communicated with the sealing cover. Through collaborative design of the threaded sleeve, the sealing cover, the air bag and other components, multiple steps of dripping normal saline, collecting detection liquid and conveying the detection liquid to a tear mmp-9 detection reagent card detection area are integrated, and the situation that the detection liquid is transferred among multiple carriers such as the intraocular part, a test tube, a dropper and a tear mmp-9 detection reagent card in a traditional mode is not needed, so that the detection efficiency is improved, and the detection cost is reduced. The operation process is greatly simplified, and the operation difficulty and workload of detection personnel are reduced.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present invention belongs to the technical field of medical devices, and in particular relates to a tear detection device. Background Art

[0002] Dry eye syndrome is a common ophthalmic disease. Its diagnosis usually requires testing and analysis of relevant substances in the eye. Among them, detecting MMP-9 antibodies to determine the condition of dry eye syndrome is one of the commonly used detection methods.

[0003] In the existing MMP-9 antibody testing process, it is usually necessary to first drop physiological saline into the eyes, use the physiological saline to mix with the intraocular substances to form a test solution, then collect the mixed test solution through a test tube, and then use a dropper to input the test solution in the test tube into the tear MMP-9 test reagent card, and finally insert the tear MMP-9 test reagent card into the tear MMP-9 detector for detection and analysis.

[0004] The entire testing process involves multiple steps and the operation is extremely complicated. The testing liquid needs to be transferred multiple times between multiple carriers such as the eye, test tubes, droppers, tear MMP-9 test reagent cards, etc. The multiple transfers of the testing liquid not only increase the workload and operation time of the testing personnel and reduce the testing efficiency, but also easily cause contamination or loss of the testing liquid during the transfer process, affecting the accuracy and reliability of the test results.

[0005] In view of this, the present invention is proposed. Summary of the Invention

[0006] In order to solve the above technical problems, the basic concept of the technical solution adopted by the present invention is:

[0007] A tear detection device comprises a tear MMP-9 detector.

[0008] The tear MMP-9 detector is provided with a detection chamber, a tear MMP-9 detection reagent card is arranged inside the detection chamber, a threaded sleeve is threadedly installed on the surface of the tear MMP-9 detector, and the threaded sleeve is placed above the detection chamber, a delivery hose is connected to the top of the threaded sleeve, a sealing cover that is connected to the delivery hose is rotatably installed on the bottom of the threaded sleeve, and the sealing cover is vertically slidably arranged in the detection chamber, the sealing cover corresponds to the detection area on the tear MMP-9 detection reagent card, and the threaded sleeve rotates to drive the sealing cover to press down, thereby sealing the detection area on the tear MMP-9 detection reagent card;

[0009] The tear MMP-9 detector is equipped with an air bag, which is communicated with the sealing cover. The air bag is used to attract the detection liquid to flow to the detection area of ​​the tear MMP-9 detection reagent card.

[0010] As a preferred embodiment of the present invention, a handle is installed on the side wall of the tear mmp-9 detector, and anti-slip grooves are provided on the surface of the handle and the bottom of the tear mmp-9 detector.

[0011] As a preferred embodiment of the present invention, one end of the detection cavity is connected to a socket, and the surface of the tear MMP-9 detection reagent card is movably inserted into the socket. The top of the detection cavity is connected to a threaded hole, and the threaded hole is rotatably connected to the threaded sleeve. A connecting rod is installed on the end face of the threaded sleeve, and a protrusion is installed on the connecting rod. The connecting rod and the protrusion are L-shaped.

[0012] As a preferred embodiment of the present invention, a sleeve is installed through the inside of the threaded sleeve, the bottom of the sleeve is rotatably connected to the sealing cover, the top of the sleeve is sleeved with a connecting cover, the connecting cover is connected to the bottom of the conveying hose, and the top of the conveying hose is connected to a guide bucket.

[0013] As a preferred embodiment of the present invention, four slides are installed on the side wall of the sealing cover, and a limit rod is provided inside each slide for movement. The limit rod is installed in the detection cavity, and a limit spring is sleeved on the limit rod. One end of the limit spring is clamped on the slide, and the other end is clamped on the side wall of the detection cavity.

[0014] As a preferred embodiment of the present invention, a sealing gasket for improving sealing is installed at the bottom of the sealing cover, and a negative pressure tube is also connected to the sealing cover. The negative pressure tube runs through the tear mmp-9 detector housing, and the negative pressure tube is connected to the airbag.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] The present invention integrates multiple steps of instilling physiological saline, collecting detection liquid, and transporting it to the detection area of ​​the tear MMP-9 detection reagent card through the coordinated design of components such as the threaded sleeve, the sealing cover, and the air bag. There is no need to transfer the detection liquid between multiple carriers such as the eye, test tube, dropper, tear MMP-9 detection reagent card, etc. as in the traditional method, which greatly simplifies the operation process and reduces the operating difficulty and workload of the detection personnel.

[0017] The specific embodiments of the present invention will be described in further detail below with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In the attached figure:

[0019] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0020] Figure 2 It is an overall diagram of the present invention;

[0021] Figure 3 It is a partial cross-sectional view of the present invention;

[0022] Figure 4 Part of the present invention Figure 1 ;

[0023] Figure 5 Part of the present invention Figure 2 ;

[0024] Figure 6 It is a partial assembly diagram of the present invention.

[0025] In the figure: 1. Tear MMP-9 detector; 2. Handle; 3. Detection chamber; 4. Threaded hole; 5. Socket; 6. Tear MMP-9 detection reagent card; 7. Threaded sleeve; 8. Protrusion; 9. Connecting rod; 10. Sleeve; 11. Delivery hose; 12. Guide bucket; 13. Connecting cover; 14. Sealing cover; 15. Airbag; 16. Negative pressure tube; 17. Slide plate; 18. Limit rod; 19. Limit spring; 20. Sealing gasket. DETAILED DESCRIPTION

[0026] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. The following embodiments are used to illustrate the present invention.

[0027] like Figures 1 to 6 As shown, a tear detection device includes a tear MMP-9 detector 1.

[0028] A detection chamber 3 is provided on the tear MMP-9 detector 1, and a tear MMP-9 detection reagent card 6 is arranged inside the detection chamber 3. A threaded sleeve 7 is threadedly installed on the surface of the tear MMP-9 detector 1, and the threaded sleeve 7 is placed above the detection chamber 3. A delivery hose 11 is connected to the top of the threaded sleeve 7, and a sealing cover 14 that is interconnected with the delivery hose 11 is rotatably installed on the bottom of the threaded sleeve, and the sealing cover 14 is vertically slidably arranged in the detection chamber 3. The sealing cover 14 corresponds to the detection area on the tear MMP-9 detection reagent card 6. The rotation of the threaded sleeve 7 drives the sealing cover 14 to press down, thereby sealing the detection area on the tear MMP-9 detection reagent card 6. This integrated sealing design effectively reduces the risk of the detection liquid contacting the outside world during transmission, and improves the accuracy of the test results.

[0029] The tear MMP-9 tester 1 is equipped with an airbag 15, which is connected to the sealing cover 14. The airbag 15 is used to draw the test fluid toward the detection area of ​​the tear MMP-9 test reagent card 6. Compared with traditional mechanical suction devices, the airbag provides negative pressure, which is lower in cost and easier to operate. Medical staff can quickly create a negative pressure environment by manually squeezing and releasing the airbag, accelerating the transfer of the test fluid and improving detection efficiency.

[0030] like Figures 1 to 6 As shown, in a specific embodiment, a handle 2 is installed on the side wall of the tear MMP-9 detector 1, and anti-slip grooves are provided on the surface of the handle 2 and the bottom of the tear MMP-9 detector 1. The design of the handle 2 and the anti-slip groove greatly improves the stability of the device during operation. Even if medical staff operate for a long time, it is not easy to cause the device to shake due to hand slippage, ensuring a smooth detection process.

[0031] like Figures 1 to 6 As shown, one end of the detection chamber 3 is connected to a socket 5, and the surface of the tear MMP-9 detection reagent card 6 is movably inserted into the socket 5. The top of the detection chamber 3 is connected to a threaded hole 4, which is rotatably connected to a threaded sleeve 7. A connecting rod 9 is installed on the end face of the threaded sleeve 7, and a protrusion 8 is installed on the connecting rod 9. The connecting rod 9 and the protrusion 8 form an L-shape that is easy to rotate. The L-shaped connecting rod 9 and the protrusion 8 are designed in accordance with ergonomic principles. Medical staff can easily apply force to rotate the threaded sleeve 7, reducing the operating intensity and not easily causing fatigue even with frequent operation.

[0032] like Figures 1 to 6 As shown, a sleeve 10 is installed inside the threaded sleeve 7. The bottom of the sleeve 10 is rotatably connected to the sealing cover 14. The top of the sleeve 10 is provided with a connecting cover 13. The connecting cover 13 is connected to the bottom of the delivery hose 11. The top of the delivery hose 11 is connected to a guide bucket 12. The delivery hose 11 has good flexibility and can be flexibly adjusted according to actual testing needs. It is convenient for accurately dripping physiological saline into the eye and also facilitates the collection of test fluid, making the testing operation more flexible and convenient.

[0033] like Figures 1 to 6 As shown, four slides 17 are mounted on the sidewalls of the sealing cover 14. Each slide 17 is provided with a limit rod 18 that movably extends therethrough. The limit rod 18 is mounted in the detection chamber 3. A limit spring 19 is sleeved on the limit rod 18. One end of the limit spring 19 is engaged with the slide 17, and the other end is engaged with the sidewall of the detection chamber 3. The combination of the slide 17, the limit rod 18, and the limit spring 19 effectively limits the movement direction of the sealing cover 14, ensuring that the sealing cover 14 always remains vertical during its upward and downward movement, preventing tilt that could affect the sealing effect, and further improving the reliability of the detection.

[0034] like Figures 1 to 6 As shown, a sealing gasket 20 is installed at the bottom of the sealing cover 14 to improve the sealing performance. A negative pressure tube 16 is also connected to the sealing cover 14. The negative pressure tube 16 is movable through the housing of the tear MMP-9 detector 1 and is in communication with the airbag 15. The use of the sealing gasket 20 can further enhance the sealing between the sealing cover 14 and the detection area of ​​the tear MMP-9 detection reagent card 6, preventing the leakage of the detection liquid or the ingress of external impurities, providing a double guarantee for the accuracy of the test results.

[0035] The implementation principle of a tear detection device is as follows:

[0036] When performing a dry eye test, the tear MMP-9 test reagent card 6 is first inserted into the test chamber 3 through the insertion hole 5, so that the test area of ​​the tear MMP-9 test reagent card 6 is located at a corresponding position below the sealing cover 14. Then, the operator grasps the handle 2, and the anti-slip grooves on the surface of the handle 2 and the bottom of the tear MMP-9 tester 1 ensure a stable grip.

[0037] Subsequently, the connecting rod 9 is rotated. Since the connecting rod 9 and the protrusion 8 are in an L-shape, it is convenient to apply force, driving the threaded sleeve 7 to rotate in the threaded hole 4. As the threaded sleeve 7 rotates and moves downward, it also drives the sleeve 10, the connecting cover 13, the delivery hose 11 and the sealing cover 14 to move downward. The slide 17 on the side wall of the sealing cover 14 slides along the limit rod 18, and the limit spring 19 is compressed. When the sealing gasket 20 at the bottom of the sealing cover 14 is tightly fitted with the detection area on the tear MMP-9 detection reagent card 6, the rotation of the connecting rod 9 is stopped. At this time, the threaded sleeve 7 drives the sealing cover 14 to press down, completing the sealing of the detection area of ​​the tear MMP-9 detection reagent card 6.

[0038] And the operator needs to squeeze the airbag 15 so that the airbag 15 is in a compressed state.

[0039] The operator then drips physiological saline into the eye and leaves it for a while to allow the saline to fully mix with the intraocular substances to form a test solution. The guide bucket 12 is then placed against the corner of the eye. The patient turns their head, and under the effects of gravity and liquid fluidity, the mixed solution in the eye flows toward the guide bucket 12. At this point, the compressed airbag 15 is released. As the airbag 15 returns to its original state, the internal space increases and the air pressure decreases, creating a negative pressure environment within the sealing cover 14 through the negative pressure tube 16. Under the strong suction of the negative pressure, the test solution in the guide bucket 12 enters the sealing cover 14 in sequence through the delivery hose 11, the connecting cover 13, and the sleeve 10, ultimately flowing to the detection area of ​​the tear MMP-9 test reagent card 6.

[0040] Finally, the detection area on the tear MMP-9 detection reagent card 6 is detected by the tear MMP-9 detector 1, wherein the specific working principle of the tear MMP-9 detector 1 is the existing technology and will not be repeated here.

Claims

1. A tear detection device, comprising a tear MMP-9 detector (1), characterized in that: The tear MMP-9 detector (1) is provided with a detection chamber (3), and a tear MMP-9 detection reagent card (6) is arranged inside the detection chamber (3). A threaded sleeve (7) is rotatably mounted on the surface of the tear MMP-9 detector (1), and the threaded sleeve (7) is placed above the detection chamber (3). A delivery hose (11) is connected to the top of the threaded sleeve (7), and a sealing cover (14) that is interconnected with the delivery hose (11) is rotatably mounted on the bottom of the threaded sleeve, and the sealing cover (14) is vertically slidably arranged in the detection chamber (3). The sealing cover (14) corresponds to the detection area on the tear MMP-9 detection reagent card (6), and the threaded sleeve (7) rotates to drive the sealing cover (14) to press down, thereby sealing the detection area on the tear MMP-9 detection reagent card (6); The tear MMP-9 detector (1) is provided with an air bag (15), and the air bag (15) and the sealing cover (14) are in communication with each other. The air bag (15) is used to attract the detection liquid to flow to the detection area of ​​the tear MMP-9 detection reagent card (6).

2. The tear detection device according to claim 1, characterized in that: A handle (2) is installed on the side wall of the tear MMP-9 detector (1), and anti-slip grooves are provided on the surface of the handle (2) and the bottom of the tear MMP-9 detector (1).

3. The tear detection device according to claim 1, characterized in that: One end of the detection chamber (3) is connected to a socket (5), and the surface of the tear MMP-9 detection reagent card (6) is movably plugged into the socket (5). The top of the detection chamber (3) is connected to a threaded hole (4), and the threaded hole (4) is rotatably connected to the threaded sleeve (7). A connecting rod (9) is installed on the end surface of the threaded sleeve (7), and a protrusion (8) is installed on the connecting rod (9). The connecting rod (9) and the protrusion (8) are L-shaped.

4. The tear detection device according to claim 1, characterized in that: A sleeve (10) is installed through the threaded sleeve (7), the bottom of the sleeve (10) is rotatably connected to the sealing cover (14), the top of the sleeve (10) is sleeved with a connecting cover (13), the connecting cover (13) is connected to the bottom of the delivery hose (11), and the top of the delivery hose (11) is connected to a guide bucket (12).

5. The tear detection device according to claim 1, characterized in that: Four slides (17) are installed on the side wall of the sealing cover (14), and a limit rod (18) is movably provided inside each of the slides (17). The limit rod (18) is installed in the detection chamber (3), and a limit spring (19) is sleeved on the limit rod (18). One end of the limit spring (19) is clamped on the slide (17), and the other end is clamped on the side wall of the detection chamber (3).

6. The tear detection device according to claim 1, characterized in that: A sealing gasket (20) for improving sealing performance is installed at the bottom of the sealing cover (14), and a negative pressure tube (16) is also connected to the sealing cover (14). The negative pressure tube (16) movably passes through the shell of the tear MMP-9 detector (1), and the negative pressure tube (16) is connected to the air bag (15).