Full-automatic platelet-rich plasma gel preparation device

Abstract

The invention discloses a full-automatic platelet-rich plasma gel preparation device, and relates to the field of medical instruments, the full-automatic platelet-rich plasma gel preparation device comprises a box body, an inner cavity of the box body is divided into three independent areas through partition plates, and each independent area is provided with a box door which can be independently opened and closed; the PRP output assembly, the activator output assembly, the mixed reaction assembly and the PRP gel pumping assembly are all arranged at the top of the supporting frame, the heating assembly is arranged on the side, away from the open end of the mixed reaction area, of the mixed reaction area and electrically connected with a control platform arranged in the control platform mounting area, and the gel output assembly is detachably arranged in the gel output area and electrically connected with the control platform. The PRP output assembly, the activator output assembly, the mixed reaction assembly, the PRP gel pumping assembly and the gel output assembly are sequentially communicated through pipelines. The full-process closed and automatic operation of PRP gel preparation is realized, external environmental pollution is effectively isolated, and manual intervention links are reduced, so that the problems of proportional error and uneven mixing are avoided.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to a fully automatic platelet-rich plasma gel preparation device. Background Art

[0002] Platelet-rich plasma (PRP) gel, rich in growth factors and fibrin network, has shown significant clinical value in tissue repair, wound healing and regenerative medicine.

[0003] However, the existing technology for preparing PRP gel mostly involves manual pipetting and mixing in an open laboratory environment. Environmental microorganisms and suspended particles can easily contaminate the bioactive ingredients, resulting in loss of sterility control of the product and potential infection risks in clinical applications. At the same time, the mixing ratio of the activator and PRP depends on the operator's experience. Ratio deviation can easily lead to uneven gel polymerization speed, insufficient fiber structure strength or degradation of bioactivity, which directly affects the stability of the treatment effect. In addition, the equipment in each link is independent (such as manual injection pumps, magnetic stirrers, and constant temperature water baths), and material transfer is frequent, which not only prolongs the preparation cycle, but also increases the risk of cross-contamination due to manual contact.

[0004] Therefore, how to provide a fully automatic platelet-rich plasma gel preparation device to achieve full-process closure and automation of PRP gel preparation, effectively isolate external environmental pollution, and reduce manual intervention to avoid proportion errors and uneven mixing problems has become a technical problem that needs to be urgently solved by people in this field. Summary of the Invention

[0005] The purpose of the present invention is to provide a fully automatic platelet-rich plasma gel preparation device to achieve full-process closed and automated operation of PRP gel preparation, effectively isolate external environmental pollution, and reduce manual intervention links to avoid proportion errors and uneven mixing problems.

[0006] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0007] The present invention discloses a fully automatic platelet-rich plasma gel preparation device, comprising a box, a control platform, a heating component, a PRP output component, an activator output component, a mixing reaction component, a PRP gel pumping component and a gel output component. A plurality of partitions are arranged horizontally in the inner cavity of the box, and the partitions divide the inner cavity of the box into three independent areas including a mixing reaction area, a gel output area and a control platform installation area. The mixing reaction area and the gel output area are both provided with doors that can be opened and closed separately. A support frame is provided at the bottom of the mixing reaction component. The PRP output component, the activator output component, the mixing reaction component and the PRP gel are The pumping components are all arranged on the top of the support frame, the heating component is arranged on the side of the mixing reaction area away from its open end, the gel output component is detachably arranged in the gel output area, the PRP output component and the activator output component are both connected to the mixing reaction component through the pipeline, the mixing reaction component, the PRP gel pumping component and the gel output component are connected in sequence through the pipeline, the control platform is arranged in the control platform installation area, and the heating component, PRP output component, activator output component, mixing reaction component, PRP gel pumping component and gel output component are all electrically connected to the control platform.

[0008] Preferably, the control platform includes a panel, a display screen, buttons and a PLC controller. The panel is fixedly connected to the opening side of the control platform installation area. The display screen and buttons are integrated on the panel. The PLC controller is arranged in the inner cavity of the control platform installation area. The display screen and buttons are electrically connected to the PLC controller.

[0009] Preferably, the PRP output component includes a first hook, a first liquid storage bag, a first reciprocating injection pump, a first four-way joint, a first solenoid valve, a first one-way valve, a second solenoid valve and a first gas delivery component, the first liquid storage bag is hung on the first vertical plate set at the top of the support frame through the first hook, the first reciprocating injection pump is placed on the top of the support frame, one end of the first four-way joint is connected to the interface of the first reciprocating injection pump, the other end of the first four-way joint is connected to the bottom of the first liquid storage bag through a first pipe, and a first solenoid valve is provided on the first pipe, the other end of the first four-way joint is connected to the feed end of the second pipe, the discharge end of the second pipe is connected to the mixed reaction component, and a first one-way valve is provided on the second pipe, the other end of the first four-way joint is connected to the first gas delivery component, and a second solenoid valve is installed between the first gas delivery component and the first four-way joint, the first reciprocating injection pump, the first solenoid valve and the second solenoid valve are all electrically connected to the PLC controller.

[0010] Preferably, the activator output component includes a second hook, a second liquid storage bag, a second reciprocating syringe pump, a second four-way joint, a third solenoid valve, a second one-way valve, a fourth solenoid valve and a second gas delivery component. The second liquid storage bag is hung on the second vertical plate arranged on the top of the support frame through the second hook, the second reciprocating syringe pump is placed on the top of the support frame, one end of the second four-way joint is connected to the interface of the second reciprocating syringe pump, the other end of the second four-way joint is connected to the bottom of the second liquid storage bag through a third pipe, and a third solenoid valve is provided on the third pipe, the other end of the second four-way joint is connected to the feed end of the fourth pipe, the discharge end of the fourth pipe is connected to the mixed reaction component, and a second one-way valve is provided on the fourth pipe, the other end of the second four-way joint is connected to the second gas delivery component, and a fourth solenoid valve is installed between the second four-way joint and the second gas delivery component, and the second reciprocating syringe pump, the third solenoid valve and the fourth solenoid valve are all electrically connected to the PLC controller.

[0011] Preferably, the heating assembly includes a heating tube, an insulation plate, a fan and a temperature sensor. The heating tube is arranged on the side wall of the mixed reaction zone away from its open end. The insulation plate is horizontally arranged on the side of the mixed reaction zone close to the heating tube, and divides the mixed reaction zone into two areas, a heating zone and a working zone. Openings for air circulation are provided at the upper and lower ends of the insulation plate. Multiple groups of fans are symmetrically installed at the openings of the insulation plate to accelerate the air flow between the heating zone and the working zone. The inner cavity surface of the mixed reaction zone, the insulation plate and the outer surface of the partition are all coated with an insulation coating. The temperature sensor is installed on the side of the insulation plate away from the heating tube. The heating tube, fan and temperature sensor are all electrically connected to the PLC controller.

[0012] Preferably, the mixed reaction assembly includes a fluid mixer and a stirring storage tank connected in sequence in the direction of liquid flow, the fluid mixer includes a first input pipe, a mixer housing, a second input pipe, a vortex generator, a mixing unit and a first output pipe, the outer edge surface of the first input pipe is sleeved with the mixer housing, the middle part of the mixer housing is connected to the second input pipe, the outlet end of the first input pipe is connected to the vortex generator, the first output pipe is connected to the outlet of the mixer housing, the mixing unit is installed in the internal cavity of the first output pipe, the second pipe is connected to the first input pipe, and the fourth pipe is connected to the second input pipe;

[0013] The stirring storage tank includes a storage tank body, a bottle stopper, a drive motor, a stirring rod, a stirring paddle, a first three-way joint, a third gas delivery assembly, a fifth solenoid valve, and a sixth solenoid valve. The storage tank body is configured as a hollow structure with an open top. The bottle stopper is connected to the top opening of the storage tank body. The drive motor is mounted on the top of the bottle stopper. One end of the stirring rod is fixedly connected to the power output end of the drive motor, and the other end of the stirring rod passes through the bottle stopper and is fixedly connected to the stirring paddle. A first input port and a first output port are respectively defined on the left and right sides of the storage tank body. The first output pipe is connected to the first input port via a fifth pipe. One end of the first three-way joint is connected to the first output port, and a fifth solenoid valve is installed between the first three-way joint and the first output port. The other end of the first three-way joint is connected to the PRP gel pumping assembly via a sixth pipe. The remaining end of the first three-way joint is connected to the third gas delivery assembly, and a sixth solenoid valve is installed between the first three-way joint and the third gas delivery assembly. The drive motor, the fifth solenoid valve, and the sixth solenoid valve are all electrically connected to the PLC controller.

[0014] Preferably, the PRP gel pumping assembly includes a third reciprocating syringe pump, a second three-way connector, a third one-way valve and a fourth one-way valve. The third reciprocating syringe pump is placed on the top of the support frame, one end of the second three-way connector is connected to the interface of the third reciprocating syringe pump, the other end of the second three-way connector is connected to the sixth pipe, and the sixth pipe is provided with a third one-way valve, the remaining end of the second three-way connector is connected to the gel output assembly through the seventh pipe, and the seventh pipe is provided with a fourth one-way valve, and the third reciprocating syringe pump is electrically connected to the PLC controller.

[0015] Preferably, the gel output component includes any one of a PRP gel sheet forming component and a PRP gel microsphere preparation component detachably mounted in the gel output area;

[0016] The PRP gel sheet forming assembly includes a shell, a first electric telescopic rod, an upper extrusion punch, a lower extrusion die, a second electric telescopic rod, a guide slide, a guide rail and a pressure sensor. The shell is placed at the bottom of the gel output area, and the shell is configured as a cavity structure with an opening on the front side. The first electric telescopic rod is fixedly connected to the top of the inner cavity of the shell, the telescopic end of the first electric telescopic rod is fixedly connected to the upper extrusion punch, the bottom of the lower extrusion die is provided with a guide rail, the bottom of the shell is provided with a guide slide matching the guide rail, the lower extrusion die is slidably connected to the bottom of the inner cavity of the shell, and a pressure sensor for detecting the installation position of the lower extrusion die is provided on the rear side of the inner cavity of the shell. The second electric telescopic rod is fixedly connected to either left or right side of the shell, and the discharge end of the seventh pipe is clamped and connected to the telescopic end of the second electric telescopic rod. The first electric telescopic rod, the second electric telescopic rod and the pressure sensor are all electrically connected to the PLC controller;

[0017] The PRP gel microsphere preparation component includes a reaction chamber, a microporous pipe, a stirring component, an automatic opening and closing door component and a continuous phase conveying component. The reaction chamber is placed at the bottom of the gel output area, the outlet end of the microporous pipe is threadedly connected to the bottom opening of the reaction chamber, and the inlet end of the microporous pipe is connected to the outlet end of the seventh pipe. The stirring component is arranged at the top of the reaction chamber, the working end of the stirring component is located in the inner cavity of the reaction chamber, and the stirring paddle of the stirring component is arranged adjacent to the outlet end of the microporous pipe. The continuous phase conveying component is placed at the bottom of the gel output area and is located on one side of the reaction chamber. The continuous phase conveying component is connected to the top of the reaction chamber through a pipe and is used to convey lubricating oil into the reaction chamber. The automatic opening and closing door component is arranged at the bottom open end of the reaction chamber and is located above the microporous pipe. The stirring component, the automatic opening and closing door component and the continuous phase conveying component are all electrically connected to the PLC controller.

[0018] Preferably, a sealing assembly is further included, which includes a threaded tube, a threaded sleeve, a first sealing rubber ring and a second sealing rubber ring, the first sealing rubber ring and the second sealing rubber ring are both mounted on the threaded tube, the partition is provided with an opening for the pipeline to pass through, the threaded end of the threaded tube is arranged to pass through the opening, the threaded sleeve is threadedly connected to the threaded end of the threaded tube, the flange portion of the threaded tube is abutted against the bottom side of the partition through the first sealing rubber ring, the flange portion of the threaded sleeve is abutted against the top side of the partition through the second sealing rubber ring, and a center hole for the seventh pipeline to pass through is provided at the center position of the threaded tube and the threaded sleeve, and the aperture of the center hole is smaller than the outer diameter of the seventh pipeline.

[0019] Compared with the prior art, the present invention has the following beneficial technical effects:

[0020] 1) The device chamber is clearly divided into three independent areas by internal partitions: the mixing reaction area, the gel output area, and the control platform installation area. This structural design allows operators to simply open the corresponding area door when adding materials (such as PRP, activator), changing the gel output mold, or taking out the finished product. This effectively avoids spatial cross-interference between different operating steps and the intrusion of external microorganisms / impurities, significantly improving the cleanliness and operational safety of the entire gel preparation process;

[0021] 2) A core delivery and mixing system consisting of a reciprocating syringe pump, solenoid valves, one-way valves, a fluid mixer, and a stirring and storage tank precisely controlled by a PLC is employed. This structural design enables automatic, precise metered delivery and initial mixing (in the fluid mixer) of PRP and activators (such as thrombin and CaCl2 solution) according to a set ratio, followed by secondary stirring and heat-insulating reaction in the stirring and storage tank, ensuring highly accurate mixing ratios and a fully uniform reaction. Furthermore, a design that injects air into the pipeline after pumping (such as an activated carbon filter) effectively pushes any remaining PRP or activator in the pipeline into the mixing reactor and any remaining gel into the molding component, minimizing waste of expensive biomaterials and preventing pipeline clogging.

[0022] 3) The mixing reaction zone is equipped with an intelligent temperature control system consisting of a heating tube, an insulation board (separating the heating zone from the working zone), a fan (forced air convection circulation), and a temperature sensor. The insulation board combined with the thermal insulation coating effectively blocks the direct heat radiation from the heating tube to the mixing reaction components (fluid mixer, stirring storage tank) in the working zone. The fan drives the hot air to be evenly distributed, and the temperature sensor provides real-time feedback control, which together ensures that the working zone temperature quickly reaches the set value and remains highly uniform and stable, providing an ideal constant temperature environment for the PRP gelation reaction and avoiding uneven reaction caused by local overheating. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] The present invention will be further described below with reference to the accompanying drawings.

[0024] Figure 1 This is a schematic diagram of the overall structure of a fully automatic platelet-rich plasma gel preparation device of the present invention. Figure 1 ;

[0025] Figure 2 This is a schematic diagram of the overall structure of a fully automatic platelet-rich plasma gel preparation device of the present invention. Figure 2 ;

[0026] Figure 3 Schematic diagram of the structure of the PRP output component of the present invention;

[0027] Figure 4 Schematic diagram of the structure of the activator output component of the present invention;

[0028] Figure 5 Schematic diagram of the structure of the sealing assembly of the present invention;

[0029] Figure 6 is a structural cross-sectional view of the sealing assembly of the present invention;

[0030] Figure 7 Schematic diagram of the internal structure of the present invention;

[0031] Figure 8 For the present invention Figure 7 A magnified view of the local structure at point A;

[0032] Figure 9 Schematic diagram of the internal structure of the fluid mixer of the present invention;

[0033] Figure 10 For the present invention Figure 7 A magnified view of the local structure at point C in the middle;

[0034] Figure 11 This is a schematic structural diagram of the stirring storage tank of the present invention;

[0035] Figure 12 For the present invention Figure 7 A magnified view of the local structure at point B in the middle;

[0036] Figure 13 This is a schematic structural diagram of the PRP gel sheet forming assembly of the present invention;

[0037] Figure 14 This is a schematic structural diagram of the PRP gel microsphere preparation assembly of the present invention.

[0038] Explanation of reference numerals: 1. Box body; 101. Partition; 102. Box door; 103. Support frame; 104. Mixing reaction area; 105. Gel output area; 2. Control platform; 201. Panel; 202. Display screen; 203. Button; 3. Heating assembly; 301. Heating tube; 302. Heat insulation board; 303. Fan; 4. PRP output assembly; 401. First hook; 402. First liquid storage bag; 403. First reciprocating injection pump; 404. First four-way connector; 405. First solenoid valve; 406. First one-way valve; 407. Second solenoid valve Magnetic valve; 408, first gas delivery assembly; 5, activator output assembly; 501, second hook; 502, second liquid storage bag; 503, second reciprocating syringe pump; 504, second four-way connector; 505, third solenoid valve; 506, second one-way valve; 507, fourth solenoid valve; 508, second gas delivery assembly; 6, mixing reaction assembly; 601, fluid mixer; 6011, first input pipe; 6012, mixer housing; 6013, second input pipe; 6014, vortex generator; 6015, mixing unit; 6016, first output pipe; 6 02. Mixing storage tank; 6021. Storage tank body; 6022. Bottle stopper; 6023. Drive motor; 6024. Stirring rod; 6025. Stirring paddle; 6026. First three-way connector; 6027. Third gas delivery assembly; 6028. Fifth solenoid valve; 6029. Sixth solenoid valve; 7. PRP gel pumping assembly; 701. Third reciprocating syringe pump; 702. Second three-way connector; 703. Third one-way valve; 704. Fourth one-way valve; 8. Gel output assembly; 801. PRP gel sheet forming assembly; 8011. Housing; 80 12. First electric telescopic rod; 8013. Upper extrusion punch; 8014. Lower extrusion die; 8015. Second electric telescopic rod; 8016. Guide chute; 8017. Guide rail; 8018. Pressure sensor; 802. PRP gel microsphere preparation assembly; 8021. Reaction chamber; 8022. Microporous pipe; 8023. Stirring assembly; 8024. Automatic door opening and closing assembly; 8025. Continuous phase conveying assembly; 9. Sealing assembly; 901. Threaded pipe; 902. Threaded sleeve; 903. First sealing rubber ring; 904. Second sealing rubber ring. DETAILED DESCRIPTION

[0039] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0040] like Figure 1-14As shown, a fully automatic platelet-rich plasma gel preparation device includes a box 1, a control platform 2, a heating component 3, a PRP output component 4, an activator output component 5, a mixing reaction component 6, a PRP gel pumping component 7 and a gel output component 8. A plurality of partitions 101 are arranged horizontally in the inner cavity of the box 1. The partitions 101 divide the inner cavity of the box 1 into three independent areas including a mixing reaction area 104, a gel output area 105 and a control platform installation area. The mixing reaction area 104 and the gel output area 105 are both provided with a door 102 that can be opened and closed separately. A support frame 103 is provided at the bottom of the mixing reaction component 6. The PRP output component 4, the activator output component 5, the mixing reaction component 6 and the PRP gel pumping component 7 are all arranged on the top of the support frame 103, the heating component 3 is arranged on the side of the mixing reaction area 104 away from its open end, the gel output component 8 is detachably arranged in the gel output area 105, the PRP output component 4 and the activator output component 5 are both connected to the mixing reaction component 6 through the pipeline, the mixing reaction component 6, the PRP gel pumping component 7 and the gel output component 8 are connected in sequence through the pipeline, the control platform 2 is arranged in the control platform installation area, and the heating component 3, PRP output component 4, activator output component 5, mixing reaction component 6, PRP gel pumping component 7 and gel output component 8 are all electrically connected to the control platform 2.

[0041] Specifically, the configuration of the box 1 provides a closed environment for the molding operation of platelet-rich plasma (PRP) gel, effectively avoiding the problem of possible introduction of microorganisms or impurities in open operation.

[0042] Specifically, the present invention divides the inner cavity of the box body 1 into multiple independent areas through the partition 101. During operation, it is only necessary to open the box door 102 of the corresponding area, which can effectively avoid cross interference between different areas and ensure the cleanliness of each operating space.

[0043] Specifically, the present invention realizes the automated proportional mixing of PRP and activators (such as thrombin and CaCl2), ensuring the accuracy of the mixing ratio and the uniformity of the mixture.

[0044] Specifically, the control platform 2 includes a panel 201, a display screen 202, a button 203 and a PLC controller. The panel 201 is fixedly connected to the opening side of the control platform installation area. The display screen 202 and the button 203 are integrated on the panel 201. The PLC controller is arranged in the inner cavity of the control platform installation area. The display screen 202 and the button 203 are electrically connected to the PLC controller.

[0045] Specifically, the PRP output component 4 includes a first hook 401, a first liquid storage bag 402, a first reciprocating injection pump 403, a first four-way connector 404, a first solenoid valve 405, a first one-way valve 406, a second solenoid valve 407 and a first gas transmission component 408. The first liquid storage bag 402 is hung on the first vertical plate set on the top of the support frame 103 through the first hook 401, the first reciprocating injection pump 403 is placed on the top of the support frame 103, one end of the first four-way connector 404 is connected to the interface of the first reciprocating injection pump 403, and the other end of the first four-way connector 404 is connected to the first one-way valve 406 through the first pipeline. The bottom of the first liquid storage bag 402 is connected, and a first solenoid valve 405 is provided on the first pipeline, the other end of the first four-way connector 404 is connected to the feed end of the second pipeline, the discharge end of the second pipeline is connected to the mixed reaction component 6, and a first one-way valve 406 is provided on the second pipeline, the remaining end of the first four-way connector 404 is connected to the first gas delivery component 408, and a second solenoid valve 407 is installed between the first gas delivery component 408 and the first four-way connector 404, the first reciprocating injection pump 403, the first solenoid valve 405, and the second solenoid valve 407 are all electrically connected to the PLC controller.

[0046] Specifically, the first liquid storage bag 402 is used to store platelet-rich plasma (PRP), and the first one-way valve 406 installed on the second pipeline can effectively prevent the liquid from flowing back. The on and off of the first solenoid valve 405 and the second solenoid valve 407 are controlled by the PLC controller. Combined with the reciprocating suction function of the first reciprocating injection pump 403, the pumping of air or PRP in the first liquid storage bag 402 can be realized. When the PRP pumping task is completed, the first solenoid valve 405 is closed and the second solenoid valve 407 is opened. The first reciprocating injection pump 403 continues to transport the remaining PRP in the second pipeline by pumping air into the second pipeline, which can avoid the waste of platelet-rich plasma caused by residue in the tube.

[0047] Specifically, the activator output component 5 includes a second hook 501, a second liquid storage bag 502, a second reciprocating injection pump 503, a second four-way connector 504, a third solenoid valve 505, a second one-way valve 506, a fourth solenoid valve 507 and a second gas delivery component 508. The second liquid storage bag 502 is hung on the second vertical plate set on the top of the support frame 103 through the second hook 501, the second reciprocating injection pump 503 is placed on the top of the support frame 103, one end of the second four-way connector 504 is connected to the interface of the second reciprocating injection pump 503, and the other end of the second four-way connector 504 is connected to the second one-way valve 506 through the third pipe. The bottom of the second liquid storage bag 502 is connected, and a third solenoid valve 505 is provided on the third pipeline. The other end of the second four-way connector 504 is connected to the feed end of the fourth pipeline, and the discharge end of the fourth pipeline is connected to the mixed reaction component 6, and a second one-way valve 506 is provided on the fourth pipeline. The remaining end of the second four-way connector 504 is connected to the second gas delivery component 508, and a fourth solenoid valve 507 is installed between the second four-way connector 504 and the second gas delivery component 508. The second reciprocating injection pump 503, the third solenoid valve 505, and the fourth solenoid valve 507 are all electrically connected to the PLC controller.

[0048] Specifically, the second liquid storage bag 502 is used to store the activator solution.

[0049] Specifically, the heating assembly 3 includes a heating tube 301, an insulation plate 302, a fan 303 and a temperature sensor. The heating tube 301 is arranged on the side wall of the mixed reaction zone 104 away from its open end. The insulation plate 302 is horizontally arranged on the side of the mixed reaction zone 104 close to the heating tube 301, and divides the mixed reaction zone 104 into two areas: a heating zone and a working zone. Openings for air circulation are provided at the upper and lower ends of the insulation plate 302. Multiple groups of fans 303 are symmetrically installed at the openings of the insulation plate 302 to accelerate the air flow between the heating zone and the working zone. The inner cavity surface of the mixed reaction zone 104, the insulation plate 302 and the outer surface of the partition 101 are all coated with an insulation coating. The temperature sensor is installed on the side of the insulation plate 302 away from the heating tube 301. The heating tube 301, the fan 303 and the temperature sensor are all electrically connected to the PLC controller.

[0050] Specifically, the insulation board 302 separates the mixing reaction zone 104 into a heating zone and a working zone, effectively blocking the direct heat radiation of the heating tube 301 installed on the inner wall of the mixing reaction zone 104 to the fluid mixer 601 and the stirring storage tank 602 in the working zone, avoiding the fluctuation of the fibrin polymerization speed and quality due to local overheating in the mixing reaction zone 104, thereby ensuring the realization of PRP constant temperature gel operation; at the same time, multiple groups of fans 303 installed at the upper and lower ends of the insulation board 302 drive the air between the heating zone and the working zone to form a forced convection circulation. The fan 303 located at the top of the insulation board 302 guides the hot air from the heating zone to the working zone, while the fan 303 located at the bottom guides the cold air from the working zone to the heating zone, thereby ensuring the uniform distribution of temperature in the working zone.

[0051] Specifically, the mixed reaction assembly 6 includes a fluid mixer 601 and a stirring storage tank 602 connected in sequence according to the direction of liquid flow, the fluid mixer 601 includes a first input pipe 6011, a mixer housing 6012, a second input pipe 6013, a vortex generator 6014, a mixing unit 6015 and a first output pipe 6016, the outer edge surface of the first input pipe 6011 is sleeved with the mixer housing 6012, the middle part of the mixer housing 6012 is connected to the second input pipe 6013, the outlet end of the first input pipe 6011 is connected to the vortex generator 6014, the first output pipe 6016 is connected to the outlet of the mixer housing 6012, the mixing unit 6015 is installed in the internal cavity of the first output pipe 6016, the second pipeline is connected to the first input pipe 6011, and the fourth pipeline is connected to the second input pipe 6013;

[0052] Specifically, the mixing reaction component 6 in the present invention is an existing structure, and the microfluid mixer in the reference patent (patent number: CN212119817U) is omitted for further details.

[0053] The stirring storage tank 602 includes a storage tank body 6021, a bottle stopper 6022, a drive motor 6023, a stirring rod 6024, a stirring paddle 6025, a first three-way connector 6026, a third gas transmission component 6027, a fifth solenoid valve 6028 and a sixth solenoid valve 6029. The storage tank body 6021 is configured as a cavity structure with an opening at the top. The bottle stopper 6022 is connected to the top opening of the storage tank body 6021. The drive motor 6023 is installed on the top of the bottle stopper 6022. One end of the stirring rod 6024 is fixedly connected to the power output end of the drive motor 6023. The other end of the stirring rod 6024 passes through the bottle stopper 6022 and is fixedly connected to the stirring paddle 6025. The left and right sides of the storage tank body 6021 are A first input port and a first output port are respectively provided, the first output pipe is connected to the first input port through a fifth pipe, one end of the first three-way joint 6026 is connected to the first output port, and a fifth solenoid valve 6028 is installed between the first three-way joint 6026 and the first output port, the other end of the first three-way joint 6026 is connected to the PRP gel pumping component 7 through a sixth pipe, the remaining end of the first three-way joint 6026 is connected to the third gas delivery component 6027, and a sixth solenoid valve 6029 is installed between the first three-way joint 6026 and the third gas delivery component 6027, the driving motor 6023, the fifth solenoid valve 6028, and the sixth solenoid valve 6029 are all electrically connected to the PLC controller.

[0054] Specifically, the fluid mixer 601 and the stirring storage tank 602 are both arranged on the top of the support frame 103, so that they are located at the middle height of the mixing reaction zone 104, which helps to improve the stability of the surrounding air temperature.

[0055] Specifically, the stirring storage tank 602 is used to receive and store the mixed solution of PRP and activator from the fluid mixer 601, and perform secondary stirring. This not only prolongs the retention reaction time of the mixed solution in the mixing reaction zone 104, ensuring that it has sufficient time to complete the reaction, but also avoids the frequent start and stop of the first reciprocating injection pump 403 and the second reciprocating injection pump 503 for small-batch preparation. The storage function of the stirring storage tank 602 allows a sufficient amount of PRP gel to be prepared on demand at one time. At the same time, the stirring paddle 6025 inside it further improves the mixing uniformity of PRP and activator.

[0056] Specifically, the setting of the fifth solenoid valve 6028 can realize the pumping control of the PRP gel in the stirring storage tank 602, and the sixth solenoid valve 6029 can deliver air to the sixth pipeline through the third air delivery component 6027, so that the PRP gel remaining in the sixth pipeline and the seventh pipeline can be completely pumped out, avoiding its residue in the pipeline causing blockage of the pipeline and waste of PRP gel.

[0057] Specifically, the first gas delivery component 408, the second gas delivery component 508 and the third gas delivery component 6027 have the same structure, and are all activated carbon filters.

[0058] Specifically, the PRP gel pumping assembly 7 includes a third reciprocating injection pump 701, a second three-way connector 702, a third one-way valve 703 and a fourth one-way valve 704. The third reciprocating injection pump 701 is placed on the top of the support frame 103, one end of the second three-way connector 702 is connected to the interface of the third reciprocating injection pump 701, the other end of the second three-way connector 702 is connected to the sixth pipeline, and the sixth pipeline is provided with a third one-way valve 703, the remaining end of the second three-way connector 702 is connected to the gel output assembly 8 through the seventh pipeline, and the seventh pipeline is provided with a fourth one-way valve 704, and the third reciprocating injection pump 701 is electrically connected to the PLC controller.

[0059] Specifically, the gel output component 8 includes any one of a PRP gel sheet forming component 801 and a PRP gel microsphere preparation component 802 detachably mounted in the gel output area 105 ;

[0060] The PRP gel sheet forming assembly 801 includes a housing 8011, a first electric telescopic rod 8012, an upper extrusion punch 8013, a lower extrusion die 8014, a second electric telescopic rod 8015, a guide slide 8016, a guide rail 8017 and a pressure sensor 8018. The housing 8011 is placed at the bottom of the gel output area 105, and the housing 8011 is configured as a cavity structure with an open front side. The first electric telescopic rod 8012 is fixedly connected to the top of the inner cavity of the housing 8011. The telescopic end of the first electric telescopic rod 8012 is fixedly connected to the upper extrusion punch 8013. The bottom of the lower extrusion die 8014 is provided with a guide rail 8017. 17. A guide groove 8016 matching the guide rail 8017 is provided at the bottom of the housing 8011. The lower extrusion die 8014 is slidably connected to the bottom of the inner cavity of the housing 8011. A pressure sensor 8018 for detecting the installation position of the lower extrusion die 8014 is provided on the rear side of the inner cavity of the housing 8011. The second electric telescopic rod 8015 is fixedly connected to either the left or right side of the housing 8011, and the discharge end of the seventh pipe is snap-connected to the telescopic end of the second electric telescopic rod 8015. The first electric telescopic rod 8012, the second electric telescopic rod 8015, and the pressure sensor 8018 are all electrically connected to the PLC controller.

[0061] Specifically, after a certain amount of PRP gel is transported to the groove of the lower extrusion die 8014 through the seventh pipeline, the upper extrusion punch 8013 moves downward under the drive of the first electric telescopic rod 8012 to squeeze the PRP gel in the groove. After standing for 1 to 2 minutes, the PRP gel sheet can be formed; in addition, the sizes of the upper extrusion punch 8013 and the lower extrusion die 8014 can be freely replaced and selected according to the size of the PRP gel sheet to be prepared.

[0062] The PRP gel microsphere preparation component 802 includes a reaction chamber 8021, a microporous pipe 8022, a stirring component 8023, an automatic opening and closing door component 8024 and a continuous phase conveying component 8025. The reaction chamber 8021 is placed at the bottom of the gel output area 105, the outlet end of the microporous pipe 8022 is threadedly connected to the bottom opening of the reaction chamber 8021, and the inlet end of the microporous pipe 8022 is connected to the outlet end of the seventh pipe. The stirring component 8023 is arranged on the top of the reaction chamber 8021, and the working end of the stirring component 8023 is located in the inner cavity of the reaction chamber 8021, and the stirring component 80 The stirring paddle 23 is arranged adjacent to the outlet end of the microporous pipe 8022, the continuous phase transport component 8025 is placed at the bottom of the gel output area 105 and is located on one side of the reaction chamber 8021, the continuous phase transport component 8025 is connected to the top of the reaction chamber 8021 through a pipeline, and is used to transport lubricating oil into the reaction chamber 8021, the automatic opening and closing door component 8024 is arranged at the bottom open end of the reaction chamber 8021 and is located above the microporous pipe 8022, and the stirring component 8023, the automatic opening and closing door component 8024 and the continuous phase transport component 8025 are all electrically connected to the PLC controller.

[0063] Specifically, the PRP gel microsphere preparation component 802 in the present invention is an existing structure, and the hydrogel microsphere preparation device in the reference patent (patent number: CN222766280U) is not described in detail here.

[0064] Specifically, it also includes a sealing component 9, which includes a threaded tube 901, a threaded sleeve 902, a first sealing rubber ring 903 and a second sealing rubber ring 904. The first sealing rubber ring 903 and the second sealing rubber ring 904 are both mounted on the threaded tube 901. The partition 101 is provided with an opening for the pipeline to pass through. The threaded end of the threaded tube 901 is arranged to pass through the opening. The threaded sleeve 902 is threadedly connected to the threaded end of the threaded tube 901. The flange portion of the threaded tube 901 is abutted against the bottom side of the partition 101 through the first sealing rubber ring 903. The flange portion of the threaded sleeve 902 is abutted against the top side of the partition 101 through the second sealing rubber ring 904. A center hole for the seventh pipeline to pass through is provided at the center position of the threaded tube 901 and the threaded sleeve 902. The aperture of the center hole is smaller than the outer diameter of the seventh pipeline.

[0065] Specifically, the provision of the sealing assembly 9 can improve the airtightness between the pipeline and the opening of the partition 101, thereby ensuring the separation and sealing of different independent areas in the box body 1.

[0066] The use process of the present invention is as follows:

[0067] First, the operator opens the door 102 of the mixing reaction area 104, hangs the first liquid storage bag 402 containing platelet-rich plasma (PRP) on the first hook 401, and connects it to the first pipe at the bottom. At the same time, the operator hangs the second liquid storage bag 502 containing the activator on the second hook 501 and connects it to the third pipe at the bottom. Then, according to the required gel form (sheet or microsphere), the operator selects and installs the corresponding gel output component (PRP gel sheet forming component 801 or PRP gel microsphere preparation component 802) into the gel output area 105, closes the doors of the mixing reaction area and the gel output area, and ensures that a closed environment is formed inside the box 1.

[0068] Secondly, the operator sets the working parameters through the panel 201 of the control platform 2, including the mixing ratio of PRP and activator, the temperature required for the mixing reaction, the reaction time, and the specific requirements for the final gel formation (such as sheet thickness or microsphere size). After the settings are completed, the device is started. The PLC controller first controls the heating component 3 to work according to the program. The heating tube 301 heats the air, and the fan 303 drives the hot air through the upper and lower openings of the insulation board 302 to force convection circulation between the working area and the heating area. The temperature sensor monitors and feedbacks the temperature to ensure that the temperature of the working area of ​​the mixing reaction zone 104 quickly reaches and stabilizes at the set value, providing a constant temperature environment for the subsequent mixing reaction.

[0069] Again, the PLC controller controls the PRP output component 4 and the activator output component 5 to work together, opens the first solenoid valve 405 and the third solenoid valve 505, closes the second solenoid valve 407 and the fourth solenoid valve 507, starts the first reciprocating injection pump 403 and the second reciprocating injection pump 503, and accurately extracts the set volume of PRP and activator solution respectively. During pumping, the first solenoid valve 405 and the third solenoid valve 505 are both closed to prevent the liquid from flowing back under pressure. The PRP is pumped to the first input pipe 6011 of the fluid mixer 601 through the first pipeline, the first four-way connector 404, and the second pipeline; the activator is pumped to the second input pipe 6013 of the fluid mixer 601 through the third pipeline, the second four-way connector 504, and the fourth pipeline. The two liquids are mixed in the vortex generator 6014 and the mixing unit 6015 of the fluid mixer 601. The first efficient and uniform mixing is achieved by the following method. The mixed solution enters the stirring storage tank 602 through the first output pipe 6016 and the fifth pipe. At the same time, the PLC controller starts the drive motor 6023 of the stirring storage tank 602, driving the stirring paddle 6025 to continuously stir and heat-insulate the mixed solution in the tank to ensure that the PRP gel is fully and evenly formed. During this process, the fifth solenoid valve 6028 and the sixth solenoid valve 6029 are in a closed state. After completing one or a set batch of mixed solution delivery, the first solenoid valve 405 and the third solenoid valve 505 are closed, and the second solenoid valve 407 and the fourth solenoid valve 507 are opened. The first reciprocating syringe pump 403 and the second reciprocating syringe pump 503 pump air to push the residual PRP or activator in the second pipe and the fourth pipe into the mixing reaction component 6, respectively, to avoid residual waste.

[0070] Then, when the PRP gel reaction in the stirring storage tank 602 is completed and the set time is reached, the PLC controller starts the gel delivery program, opens the fifth solenoid valve 6028, closes the sixth solenoid valve 6029, and starts the third reciprocating syringe pump 701 to extract the PRP gel in the stirring storage tank 602 through the sixth pipeline, and pumps it to the gel output assembly 8 installed in the gel output area 105 through the second three-way connector 702 and the seventh pipeline. When the gel delivery is nearly completed, the fifth solenoid valve 6028 is closed, the sixth solenoid valve 6029 is opened, and the third air delivery assembly 6027 delivers air to the sixth pipeline, pushing the remaining gel in the pipeline completely into the seventh pipeline to avoid waste and blockage. The third reciprocating syringe pump 701 continues to work and pushes all the gel and air in the seventh pipeline to the gel output assembly 8;

[0071] Finally, perform the molding operation according to the selected gel output component:

[0072] If the PRP gel sheet forming assembly 801 is used: a certain amount of PRP gel is pumped into the groove of the lower extrusion die 8014. During the PRP gel delivery process, the second electric telescopic rod 8015 is in an extended state. After the PRP gel delivery is completed, the second electric telescopic rod 8015 retracts to provide a clearance space for the movement of the upper extrusion punch 8013. Subsequently, the PLC controller controls the first electric telescopic rod 8012 to drive the upper extrusion punch 8013 to move downward to squeeze the gel in the groove. The pressure sensor 8018 can assist in positioning and monitoring. The gel is left to stand at the set pressure for 1-2 minutes to form a sheet.

[0073] If the PRP gel microsphere preparation assembly 802 is used: the PRP gel enters the microporous pipe 8022 through the seventh pipe, the PLC controller activates the continuous phase delivery assembly 8025 to inject the lubricating oil continuous phase into the reaction chamber 8021, and simultaneously activates the stirring assembly 8023 to stir near the micropore outlet. The gel is squeezed out of the micropore under pressure and forms microspheres in the lubricating oil under the action of shear force and surface tension;

[0074] Subsequently, the operator opens the door 102 of the gel output area 105, takes out the microsphere collection container or the formed gel sheet, turns off the system power, disassembles the pipes and used components, and cleans and disinfects them according to medical standards.

[0075] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0076] The embodiments described above are merely descriptions of preferred embodiments of the present invention and are not intended to limit the scope of the present invention. Without departing from the spirit of the present invention, various modifications and improvements made to the technical solutions of the present invention by persons skilled in the art should fall within the scope of protection defined by the claims of the present invention.

Claims

1. A fully automatic platelet-rich plasma gel preparation device, characterized by: The invention comprises a box body (1), a control platform (2), a heating component (3), a PRP output component (4), an activator output component (5), a mixing reaction component (6), a PRP gel pumping component (7) and a gel output component (8), wherein a plurality of partitions (101) are arranged transversely in the inner cavity of the box body (1), and the partitions (101) divide the inner cavity of the box body (1) into three independent areas including a mixing reaction area (104), a gel output area (105) and a control platform installation area, and the mixing reaction area (104) and the gel output area (105) are both provided with a box door (102) that can be opened and closed separately, and a support frame (103) is provided at the bottom of the mixing reaction component (6), and the PRP output component (4), the activator output component (5), the mixing reaction component (6) and the PRP gel pumping component (7) are provided. The components (7) are all arranged on the top of the support frame (103), the heating component (3) is arranged on the side of the mixing reaction zone (104) away from its open end, the gel output component (8) is detachably arranged in the gel output zone (105), the PRP output component (4) and the activator output component (5) are both connected to the mixing reaction component (6) through the pipeline, the mixing reaction component (6), the PRP gel pumping component (7) and the gel output component (8) are connected in sequence through the pipeline, the control platform (2) is arranged in the control platform installation area, and the heating component (3), the PRP output component (4), the activator output component (5), the mixing reaction component (6), the PRP gel pumping component (7) and the gel output component (8) are all electrically connected to the control platform (2).

2. The fully automatic platelet-rich plasma gel preparation device according to claim 1, characterized in that: The control platform (2) comprises a panel (201), a display screen (202), a button (203) and a PLC controller; the panel (201) is fixedly connected to the opening side of the control platform installation area; the display screen (202) and the button (203) are integrated on the panel (201); the PLC controller is arranged in the inner cavity of the control platform installation area; the display screen (202) and the button (203) are electrically connected to the PLC controller.

3. The fully automatic platelet-rich plasma gel preparation device according to claim 2, characterized in that: The PRP output assembly (4) comprises a first hook (401), a first liquid storage bag (402), a first reciprocating injection pump (403), a first four-way connector (404), a first solenoid valve (405), a first one-way valve (406), a second solenoid valve (407) and a first gas transmission assembly (408), wherein the first liquid storage bag (402) is hung on a first vertical plate arranged on the top of the support frame (103) through the first hook (401), the first reciprocating injection pump (403) is placed on the top of the support frame (103), one end of the first four-way connector (404) is connected to the interface of the first reciprocating injection pump (403), and the other end of the first four-way connector (404) is connected to the first one-way valve (405) through the first pipeline. The bottoms of the first liquid storage bag (402) are connected, and a first solenoid valve (405) is provided on the first pipeline. The other end of the first four-way connector (404) is connected to the feed end of the second pipeline, and the discharge end of the second pipeline is connected to the mixed reaction component (6). A first one-way valve (406) is provided on the second pipeline. The remaining end of the first four-way connector (404) is connected to the first gas transmission component (408), and a second solenoid valve (407) is installed between the first gas transmission component (408) and the first four-way connector (404). The first reciprocating injection pump (403), the first solenoid valve (405), and the second solenoid valve (407) are all electrically connected to the PLC controller.

4. The fully automatic platelet-rich plasma gel preparation device according to claim 3, characterized in that: The activator output component (5) includes a second hook (501), a second liquid storage bag (502), a second reciprocating injection pump (503), a second four-way connector (504), a third solenoid valve (505), a second one-way valve (506), a fourth solenoid valve (507) and a second gas delivery component (508), wherein the second liquid storage bag (502) is hung on a second vertical plate provided on the top of the support frame (103) through the second hook (501), the second reciprocating injection pump (503) is placed on the top of the support frame (103), one end of the second four-way connector (504) is connected to the interface of the second reciprocating injection pump (503), and the other end of the second four-way connector (504) is connected to the second one-way valve (506) through the third pipeline. The bottom of the second liquid storage bag (502) is connected, and a third solenoid valve (505) is provided on the third pipeline. The other end of the second four-way connector (504) is connected to the feed end of the fourth pipeline, and the discharge end of the fourth pipeline is connected to the mixed reaction component (6). A second one-way valve (506) is provided on the fourth pipeline. The remaining end of the second four-way connector (504) is connected to the second gas delivery component (508), and a fourth solenoid valve (507) is installed between the second four-way connector (504) and the second gas delivery component (508). The second reciprocating injection pump (503), the third solenoid valve (505), and the fourth solenoid valve (507) are all electrically connected to the PLC controller.

5. The fully automatic platelet-rich plasma gel preparation device according to claim 4, characterized in that: The heating assembly (3) comprises a heating tube (301), a heat insulating plate (302), a fan (303) and a temperature sensor. The heating tube (301) is arranged on the side wall of the mixing reaction zone (104) away from its open end. The heat insulating plate (302) is arranged horizontally on a side of the mixing reaction zone (104) close to the heating tube (301) and divides the mixing reaction zone (104) into two areas, a heating area and a working area. The upper and lower ends of the heat insulating plate (302) are both provided with openings for air circulation. Multiple groups of fans (303) are symmetrically installed at the opening of the insulation board (302) to accelerate the air flow between the heating zone and the working zone. The inner cavity surface of the mixed reaction zone (104), the outer surface of the insulation board (302) and the partition (101) are all coated with a thermal insulation coating. The temperature sensor is installed on the side of the insulation board (302) away from the heating tube (301). The heating tube (301), the fan (303) and the temperature sensor are all electrically connected to the PLC controller.

6. The fully automatic platelet-rich plasma gel preparation device according to claim 5, characterized in that: The mixing reaction assembly (6) comprises a fluid mixer (601) and a stirring storage tank (602) which are sequentially connected in the direction of liquid flow. The fluid mixer (601) comprises a first input pipe (6011), a mixer housing (6012), a second input pipe (6013), a vortex generator (6014), a mixing unit (6015) and a first output pipe (6016). The outer edge surface of the first input pipe (6011) is sleeved with the mixer housing (6012). The middle part of the mixer housing (6012) is connected to the second input pipe (6013), the outlet end of the first input pipe (6011) is connected to a vortex generator (6014), the first output pipe (6016) is connected to the outlet of the mixer housing (6012), the mixing unit (6015) is installed in the internal cavity of the first output pipe (6016), the second pipe is connected to the first input pipe (6011), and the fourth pipe is connected to the second input pipe (6013); The stirring storage tank (602) comprises a storage tank body (6021), a bottle stopper (6022), a driving motor (6023), a stirring rod (6024), a stirring paddle (6025), a first three-way joint (6026), a third gas transmission component (6027), a fifth solenoid valve (6028) and a sixth solenoid valve (6029). The storage tank body (6021) is configured as a cavity structure with an opening at the top. The bottle stopper (6022) is connected to the top opening of the storage tank body (6021). The driving motor (6023) is installed on the top of the bottle stopper (6022). One end of the stirring rod (6024) is fixedly connected to the power output end of the driving motor (6023). The other end of the stirring rod (6024) passes through the bottle stopper (6022) and is fixedly connected to the stirring paddle (6025). The storage tank body (60 21) are respectively provided with a first input port and a first output port, the first output pipe is connected to the first input port through a fifth pipe, one end of the first three-way joint (6026) is connected to the first output port, and a fifth solenoid valve (6028) is installed between the first three-way joint (6026) and the first output port, the other end of the first three-way joint (6026) is connected to the PRP gel pumping assembly (7) through a sixth pipe, the remaining end of the first three-way joint (6026) is connected to the third gas delivery assembly (6027), and a sixth solenoid valve (6029) is installed between the first three-way joint (6026) and the third gas delivery assembly (6027), the driving motor (6023), the fifth solenoid valve (6028), and the sixth solenoid valve (6029) are all electrically connected to the PLC controller.

7. The fully automatic platelet-rich plasma gel preparation device according to claim 6, characterized in that: The PRP gel pumping assembly (7) comprises a third reciprocating injection pump (701), a second three-way connector (702), a third one-way valve (703) and a fourth one-way valve (704); the third reciprocating injection pump (701) is placed on the top of the support frame (103); one end of the second three-way connector (702) is connected to the interface of the third reciprocating injection pump (701); the other end of the second three-way connector (702) is connected to the sixth pipeline, and the third one-way valve (703) is provided on the sixth pipeline; the remaining end of the second three-way connector (702) is connected to the gel output assembly (8) through the seventh pipeline, and the fourth one-way valve (704) is provided on the seventh pipeline; the third reciprocating injection pump (701) is electrically connected to the PLC controller.

8. The fully automatic platelet-rich plasma gel preparation device according to claim 7, characterized in that: The gel output component (8) includes any one of a PRP gel sheet forming component (801) and a PRP gel microsphere preparation component (802) detachably mounted in the gel output area (105); The PRP gel sheet forming assembly (801) comprises a housing (8011), a first electric telescopic rod (8012), an upper extrusion punch (8013), a lower extrusion die (8014), a second electric telescopic rod (8015), a guide slide (8016), a guide rail (8017) and a pressure sensor (8018). The housing (8011) is placed at the bottom of the gel output area (105), and the housing (8011) is configured as a cavity structure with an opening at the front side. The first electric telescopic rod (8012) is fixedly connected to the top of the inner cavity of the housing (8011). The telescopic end of the first electric telescopic rod (8012) is fixedly connected to the upper extrusion punch (8013). The bottom of the lower extrusion die (8014) is provided with a guide rail. (8017), the bottom of the shell (8011) is provided with a guide groove (8016) matching the guide rail (8017), the lower extrusion die (8014) is slidably connected to the bottom of the inner cavity of the shell (8011), and the rear side of the inner cavity of the shell (8011) is provided with a pressure sensor (8018) for detecting the installation position of the lower extrusion die (8014), the second electric telescopic rod (8015) is fixedly connected to either the left or right side of the shell (8011), and the discharge end of the seventh pipe is snap-connected to the telescopic end of the second electric telescopic rod (8015), and the first electric telescopic rod (8012), the second electric telescopic rod (8015) and the pressure sensor (8018) are all electrically connected to the PLC controller; The PRP gel microsphere preparation component (802) includes a reaction chamber (8021), a microporous pipe (8022), a stirring component (8023), an automatic opening and closing door component (8024) and a continuous phase conveying component (8025), wherein the reaction chamber (8021) is placed at the bottom of the gel output area (105), the outlet end of the microporous pipe (8022) is threadedly connected to the bottom opening of the reaction chamber (8021), and the inlet end of the microporous pipe (8022) is connected to the outlet end of the seventh pipe, the stirring component (8023) is arranged at the top of the reaction chamber (8021), the working end of the stirring component (8023) is located in the inner cavity of the reaction chamber (8021), and the stirring component ( The stirring paddle of the microporous pipe (8023) is arranged adjacent to the outlet end of the microporous pipe (8022), the continuous phase conveying component (8025) is placed at the bottom of the gel output area (105) and is located on one side of the reaction chamber (8021), the continuous phase conveying component (8025) is connected to the top of the reaction chamber (8021) through a pipeline, and is used to convey lubricating oil into the reaction chamber (8021), the automatic opening and closing door component (8024) is arranged at the bottom open end of the reaction chamber (8021) and is located above the microporous pipe (8022), and the stirring component (8023), the automatic opening and closing door component (8024) and the continuous phase conveying component (8025) are all electrically connected to the PLC controller.

9. The fully automatic platelet-rich plasma gel preparation device according to claim 8, characterized in that: The invention also includes a sealing assembly (9), wherein the sealing assembly (9) includes a threaded tube (901), a threaded sleeve (902), a first sealing rubber ring (903) and a second sealing rubber ring (904), wherein the first sealing rubber ring (903) and the second sealing rubber ring (904) are both sleeved on the threaded tube (901), the partition (101) is provided with an opening for a pipeline to pass through, the threaded end of the threaded tube (901) is arranged to pass through the opening, the threaded sleeve (902) and the threaded tube (901) are connected to each other. ) is threadedly connected to the threaded end of the threaded pipe (901), the flange of the threaded pipe (901) is in contact with the bottom side of the partition (101) through the first sealing rubber ring (903), and the flange of the threaded sleeve (902) is in contact with the top side of the partition (101) through the second sealing rubber ring (904), and a center hole for the seventh pipe to pass through is provided at the center position of the threaded pipe (901) and the threaded sleeve (902), and the aperture of the center hole is smaller than the outer diameter of the seventh pipe.

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