Medicated diet composition for improving eyesight, regulating spleen and increasing memory as well as preparation method and application of medicated diet composition

Abstract

The invention belongs to the technical field of health-care food, and particularly relates to a medicated diet composition for improving eyesight, regulating spleen and increasing memory as well as a preparation method and application thereof. The medicated diet composition comprises the following raw materials in parts by mass: 9-45 parts of dried snow pears, 6-30 parts of lily bulbs, 3-15 parts of radix codonopsis, 2-10 parts of dried orange peel, 1-5 parts of dried ginger and 3-15 parts of mulberries. The medicated diet composition starts from regulating five internal organs, and gathers force in the liver and the spleen through delicate compatibility and the effect of promoting generation of the five internal organs, so that the effects of improving eyesight, regulating the spleen and increasing memory can be achieved, the efficacy can be lasting, meanwhile, cold and heat purgation and tonification are balanced through medicinal compatibility, and the defect that traditional tonics are poor in nature is overcome. Clinical tests show that the medicated diet composition can effectively improve the clinical symptoms such as eye dryness, eye itching, frequent blinking, memory deterioration, dry mouth or dry throat, poor appetite and the like of patients with liver and kidney deficiency and spleen and stomach deficiency in the sub-health state, and the life quality of the patients is improved.

Description

Technical Field

[0001] The invention belongs to the technical field of health foods, and particularly relates to a medicinal food composition for improving eyesight, regulating the spleen and enhancing memory, as well as a preparation method and application thereof. Background Art

[0002] In recent years, with the acceleration of social pace and changes in lifestyle, sub-health status among the people has become increasingly common, especially dry mouth and throat, dry eyes, poor appetite, memory loss, and forgetfulness caused by excessive stress, lack of sleep, excessive eye use, and irregular diet.

[0003] Traditional Chinese Medicine has long emphasized that "food supplements are worse than medicine" and advocates using natural ingredients to harmonize the internal organs. People experiencing the aforementioned symptoms, often milder than others, tend to favor health supplements for relief. However, most health supplements currently available for these symptoms suffer from biased approaches and fail to address the underlying sub-health syndrome, resulting in incomplete treatment and suboptimal results. Therefore, it is necessary to develop health supplements that address these symptoms based on the underlying syndrome and effectively improve dry mouth and throat, dry eyes, poor appetite, memory loss, and forgetfulness. Summary of the Invention

[0004] The first object of the present invention is to provide a medicinal diet composition for improving eyesight, regulating the spleen and enhancing memory. The second object of the present invention is to provide a preparation method of the medicinal diet composition. The third object of the present invention is to provide an application of the medicinal diet composition.

[0005] According to a first aspect of the present invention, a medicinal diet composition for improving eyesight, regulating the spleen and enhancing memory is provided, the raw materials of which include, by weight: 9-45 parts of dried pear, 6-30 parts of lily, 3-15 parts of codonopsis, 2-10 parts of tangerine peel, 1-5 parts of dried ginger, and 3-15 parts of mulberry.

[0006] The present invention proposes that the pathogenesis of sub-healthy liver and kidney deficiency and spleen and stomach deficiency syndromes is as follows: excessive stress can easily lead to liver qi stagnation, staying up late can damage liver and kidney yin fluid, and an irregular diet can easily damage spleen and stomach qi. Liver and kidney yin deficiency prevents body fluid from flowing upward, resulting in dry mouth and throat. Furthermore, excessive eye use and lack of nourishment can also cause dry eyes. Spleen and stomach qi deficiency and dysfunctional transport can lead to poor appetite. Liver qi stagnation can transform into fire, disturbing the mind. Furthermore, kidney yin is depleted, yin essence is deficient, and heart and kidney communication is disjointed, resulting in memory loss and forgetfulness. Based on these pathogenesis and clinical manifestations, the present invention proposes a prescription based on Traditional Chinese Medicine syndrome differentiation and treatment.

[0007] The monarch medicine in the prescription of the present invention is dried pear and lily. Dried pear is sweet, slightly sour, and cool. It enters the lung and stomach meridians and can relieve cough and resolve phlegm, clear away heat, nourish yin and reduce fire, clear the heart and relieve vexation, and moisten the lungs and produce body fluid. Lily is sweet and cold. It enters the heart and lung meridians and can nourish yin and moisten the lungs, clear the heart and calm the mind. The two are combined to have the effects of nourishing yin and moistening the lungs, clearing the heart and calming the mind. Sufficient lung yin can nourish the whole body internal organs, promote the upward movement of essence and blood to the eyes, and improve the symptoms of dry mouth and dry throat. The heart governs the mind, clearing the heart and calming the mind can avoid the inflammation of heart fire disturbing the eyes, and help to communicate the heart and kidney. The ministerial medicine is mulberry and codonopsis. Mulberry is sweet, sour, and cold. It enters the heart, liver, and kidney meridians and can nourish yin and blood, nourish the liver and kidney, produce body fluid and moisten dryness. It increases the effect of moistening and nourishing yin of lily and dried pear. It specifically enters the heart, liver, and kidney meridians. In addition, its astringent property can lead body fluid and blood to the liver and kidney. "Medical Insights" states: "The kidneys govern intelligence; kidney deficiency leads to insufficient intelligence, resulting in a tendency to forget what one has already said. Furthermore, the heart houses the spirit, and when the spirit is deficient, forgetfulness results." This suggests that the heart and kidneys are key organs for forgetfulness. Mulberries nourish the liver and kidneys, while combined with codonopsis to tonify qi and nourish the heart and blood, and dried pears and lilies to calm the mind and soothe the mind, synergizing the heart and kidneys to enhance memory. Codonopsis is sweet and neutral, entering the lung and spleen meridians. It tonifies the middle qi, replenishes qi, nourishes blood, and produces fluids. It also invigorates the spleen and stomach, stimulating appetite. Sufficient qi and blood nourish the eyes. Tangerine peel and dried ginger serve as adjuvant herbs. Tangerine peel is bitter, pungent, and warming, entering the spleen and lung meridians, regulating qi and strengthening the spleen, drying dampness, and resolving phlegm. Dried ginger is pungent and hot, entering the spleen, stomach, kidney, heart, and lung meridians. It warms the middle qi, dispels cold, restores yang, unblocks the meridians, and warms the lungs and eliminates dampness. Combined use warms the spleen and stomach, promoting qi and blood production, while preventing yin-nourishing herbs from becoming overly nourishing and obstructing spleen and stomach function. The whole prescription is permeated with the idea of ​​"preventive treatment", which works together to nourish the liver and kidneys, improve eyesight and memory, regulate the spleen and stomach, restore the balance of internal organs, and effectively improve eye discomfort, memory loss or forgetfulness, dry mouth and throat, poor appetite and other symptoms caused by liver and kidney deficiency and spleen and stomach deficiency in sub-health status.

[0008] The sources of raw materials for this recipe are as follows:

[0009] Dried snow pear: dried fruit made from the snow pear (Pyrus nivalis) of the genus Pyrus in the Rosaceae family.

[0010] Lily: The dried fleshy scale leaves of Lilium lancifolium Thunb., Lilium browniiF.E.Brown var.viridulum Baker or Lilium pumilum DC. of the Liliaceae family.

[0011] Codonopsis: The dried roots of Codonopsis pilosula (Franch.) Nannf., Codonopsis pilosula Nannf.var.modesta (Nannf.) LTShen or Codonopsis tangshen Oliv. of the Campanulaceae family.

[0012] Tangerine peel: the dried mature peel of the Rutaceae plant Citrus reticulata Blanco and its cultivated varieties.

[0013] Dried ginger: the dried rhizome of Zingiber officinale Rosc., a plant of the ginger family.

[0014] Mulberry: the dried fruit clusters of Morus alba L., a plant of the Moraceae family.

[0015] In some embodiments, the medicinal diet composition for improving eyesight, regulating the spleen and enhancing memory comprises, by weight, 9 parts of dried pear, 6 parts of lily, 3 parts of codonopsis, 2 parts of tangerine peel, 1 part of dried ginger, and 3 parts of mulberry.

[0016] In some embodiments, the medicinal diet composition for improving eyesight, regulating the spleen and enhancing memory comprises, by weight, 25 parts of dried pear, 20 parts of lily, 9 parts of codonopsis, 7 parts of tangerine peel, 3 parts of dried ginger, and 9 parts of mulberry.

[0017] In some embodiments, food-acceptable seasonings or pharmaceutically acceptable excipients may also be added.

[0018] According to a second aspect of the present invention, there is provided a method for preparing the above-mentioned medicinal diet composition for improving eyesight, regulating the spleen and enhancing memory, comprising the following steps:

[0019] Mix all the raw materials, add 3-25 times the weight of water and boil for 30-60 minutes to obtain the product.

[0020] According to a third aspect of the present invention, there is provided a use of the above-mentioned medicinal food composition for improving eyesight, regulating the spleen and enhancing memory in the preparation of a medicament for treating liver and kidney deficiency and spleen and stomach deficiency in sub-health conditions. Specifically, the above-mentioned medicament has at least one of the following effects: (1) improving the symptoms of dry eyes; (2) improving the symptoms of itchy eyes; (3) improving the symptoms of frequent blinking; (4) improving the symptoms of memory loss; (5) improving the symptoms of forgetfulness; (6) improving the symptoms of dry mouth or dry throat; and (7) improving the symptoms of poor appetite.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] (1) The medicinal diet composition of the present invention starts with balancing the five internal organs. Through sophisticated compatibility and the interaction of the five internal organs, it focuses on the liver and spleen, achieving the effects of improving eyesight, regulating the spleen, and enhancing memory, while also making the effect last longer. At the same time, through the compatibility of medicinal properties, it balances the cold and heat attack and supplementation, overcoming the disadvantages of traditional tonics. Clinical trials have shown that the medicinal diet composition of the present invention can effectively improve clinical symptoms such as dry eyes, itchy eyes, frequent blinking, memory loss, dry mouth or dry throat, and poor appetite in patients with sub-health conditions and liver and kidney deficiency and spleen and stomach deficiency syndromes, thereby improving the quality of life of patients.

[0023] (2) The present invention selects 6 kinds of substances that are both food and Chinese medicinal materials to form a medicinal diet composition, selects dried pear and lily, which are common ingredients on the market, as the main medicine, and combines them with common Chinese medicinal materials with medicinal and edible properties on the market, such as codonopsis pilosula, tangerine peel, dried ginger, and mulberry. The ingredients are convenient to obtain, easy to operate, delicious, and inexpensive, and provide a feasible home-based medicinal diet and tea substitute for people with liver and kidney deficiency and spleen and stomach deficiency in sub-health status. DETAILED DESCRIPTION

[0024] The present invention will be further described in detail below in conjunction with specific examples. It is worth noting that the following examples are only for better explanation of the present invention and are not intended to limit the scope of protection of the present invention. The undisclosed process steps in the examples are prior art. Unless otherwise specified, the following raw materials are commercially available.

[0025] Example 1

[0026] The medicinal diet for improving eyesight, regulating the spleen and enhancing memory in this embodiment comprises the following raw materials in parts by mass: 45g dried pear, 30g lily, 15g codonopsis pilosula, 10g tangerine peel, 5g dried ginger and 15g mulberry.

[0027] The preparation method comprises the following steps:

[0028] Mix all the raw materials, add into 500mL of water, and boil for 40min until the volume reaches 200mL.

[0029] The medicinal diet prepared in this embodiment is suitable for people with sub-health conditions who suffer from liver and kidney deficiency and spleen and stomach deficiency. The dosage of one dose is 200 mL, and one dose is taken a day, which can be divided into 2-3 doses.

[0030] Example 2

[0031] The medicinal diet for improving eyesight, regulating the spleen and enhancing memory in this embodiment comprises the following raw materials in parts by mass: 9g dried pear, 6g lily, 3g codonopsis, 2g tangerine peel, 1g dried ginger and 3g mulberry.

[0032] The preparation method comprises the following steps:

[0033] Mix all the raw materials, add into 500mL of water, and boil for 50min until the volume reaches 150mL.

[0034] The medicinal diet prepared in this embodiment is suitable for people with liver and kidney deficiency and spleen and stomach deficiency in sub-health status. The dosage of one dose is 150 mL, and one dose is taken a day, which can be divided into 2-3 doses.

[0035] Example 3

[0036] The medicinal diet for improving eyesight, regulating the spleen and enhancing memory in this embodiment comprises the following raw materials in parts by mass: 25g dried pear, 20g lily, 9g codonopsis pilosula, 7g tangerine peel, 3g dried ginger and 9g mulberry.

[0037] The preparation method is the same as that of Example 2.

[0038] Effect Examples

[0039] 1. Inclusion criteria

[0040] The patient is in a sub-healthy state with liver and kidney deficiency and spleen and stomach deficiency, which manifests as dry eyes, itchy eyes, frequent blinking, memory loss or forgetfulness, dry mouth or dry throat, poor appetite and other symptoms. Just one of these symptoms will suffice.

[0041] 2. Exclusion criteria

[0042] (1) Patients who need hospitalization;

[0043] (2) Pregnant and lactating women;

[0044] (3) Subjects who are judged by the researchers to be unsuitable for participating in the study, such as those with poor compliance, lack of enthusiasm for treatment, etc., are likely to be lost to follow-up.

[0045] 3. General Information

[0046] The study subjects were 42 patients who met the inclusion criteria and did not meet the exclusion criteria collected from our hospital between 2025.05.12 and 2025.05.21.

[0047] The patients' gender, age, and follow-up data were collected, and their symptoms were scored. Pre-treatment symptoms included dry eyes, itchy eyes, frequent blinking, memory loss or forgetfulness, dry mouth or throat, and poor appetite.

[0048] All patients were given the medicated diet prepared in Example 2. The dosage was as follows: one dose per day (150 mL per dose), taken twice a day, morning and evening, for 5 consecutive days. Other medications with the effects of improving eyesight, regulating the spleen, and enhancing memory were not allowed to be taken during the medicated diet. Symptoms of the patients were scored before and after treatment to assess changes in their symptoms.

[0049] 4. Efficacy analysis

[0050] The scores of patients' dry eyes, itchy eyes, and frequent blinking symptoms before and after treatment are shown in Table 1.

[0051] Table 1 Symptom scores of dry eyes, itchy eyes and frequent blinking in patients before and after treatment

[0052]

[0053] Note: ① The scoring of dry eyes and itchy eyes symptoms is mainly based on the patient's self-perception, with 0 points for no symptoms, 1 point for mild discomfort, 2 points for moderate discomfort, 3 points for severe discomfort, and 4 points for unbearable discomfort.

[0054] ② Frequent blinking symptom score: No (0 points): During the established observation period, the blinking frequency is stable and within the normal range for the same age group, without any additional manifestations of involuntary blinking, such as the number of blinks per minute for adults is stable at 15-20 times.

[0055] Occasionally (1 point): During the observation period, the blinking frequency exceeds the normal blinking frequency for the same age group in a small amount and infrequently, which is not persistent and has little impact on daily life and social activities. For example, the blinking frequency is slightly increased 1-2 days a week, but does not exceed 5 times per day, and there is no other discomfort.

[0056] Frequent (2 points): Over a longer observation period (e.g., more than one month), the blinking frequency is significantly higher than the normal range and is relatively persistent, which has had a certain impact on daily life, study, work, or social activities. For example, an adult blinks more than 20 times per minute most of the time, which may be accompanied by eye discomfort.

[0057] Always (3 points): During almost all observation times, the blinking frequency is significantly higher than normal, presenting as continuous and compulsive blinking movements, which seriously affect visual function and quality of life, and may also be accompanied by symptoms such as pain and facial muscle twitching.

[0058] As can be seen from Table 1, the average scores of patients' dry eyes, itchy eyes, and frequent blinking symptoms after 5 days of treatment were significantly lower than those before treatment (P < 0.05), indicating that the medicinal diet composition of the present invention can effectively improve patients' dry eyes, itchy eyes, and frequent blinking symptoms.

[0059] The results of the patients' symptom scores for memory loss, dry mouth or throat, and poor appetite before and after treatment are shown in Table 2.

[0060] Table 2 Results of the patient's memory loss, dry mouth or dry throat, and poor appetite symptom scores before and after treatment

[0061]

[0062] Note: ① The scores for memory loss, dry mouth, dry throat, and poor appetite are mainly based on the patient's self-perception, with 0 points for no symptoms, 1 point for mild discomfort, 2 points for moderate discomfort, 3 points for severe discomfort, and 4 points for unbearable discomfort.

[0063] As can be seen from Table 2, the patient's memory loss, dry mouth or dry throat, and poor appetite symptom scores after 5 days of treatment were significantly lower than before treatment (P < 0.001), indicating that the medicinal diet composition of the present invention can effectively improve the patient's symptoms such as memory loss, dry mouth or dry throat, and poor appetite.

[0064] In summary, the medicinal diet composition of the present invention can effectively improve clinical symptoms such as dry eyes, itchy eyes, frequent blinking, memory loss, dry mouth or dry throat, and poor appetite in patients with sub-health conditions with liver and kidney deficiency and spleen and stomach deficiency syndrome, thereby improving the quality of life of patients.

[0065] The above descriptions are only some specific embodiments of the present invention. For those skilled in the art, several modifications and improvements can be made without departing from the creative concept of the present invention, and these all fall within the scope of protection of the present invention.

Claims

1. A medicinal food composition for improving eyesight, regulating spleen and enhancing memory, characterized in that: The raw material composition comprises, by weight, 9-45 parts of dried snow pear, 6-30 parts of lily bulbs, 3-15 parts of codonopsis pilosula, 2-10 parts of dried tangerine peel, 1-5 parts of dried ginger and 3-15 parts of mulberry.

2. The medicinal diet composition according to claim 1, characterized in that The raw material composition thereof comprises, by weight, 9 parts of dried snow pear, 6 parts of lily bulbs, 3 parts of codonopsis pilosula, 2 parts of dried tangerine peel, 1 part of dried ginger, and 3 parts of mulberry.

3. The medicinal diet composition according to claim 1, characterized in that The raw material composition thereof comprises, by weight, 25 parts of dried snow pear, 20 parts of lily bulbs, 9 parts of codonopsis pilosula, 7 parts of dried tangerine peel, 3 parts of dried ginger and 9 parts of mulberry.

4. The medicinal diet composition according to any one of claims 1 to 3, characterized in that Food-acceptable seasonings or pharmaceutically acceptable excipients may also be added.

5. The method for preparing the medicinal diet composition for improving eyesight, regulating spleen and enhancing memory according to any one of claims 1 to 4, characterized in that: The following steps are involved: Mix all the raw materials, add 3-25 times the weight of water and boil for 30-60 minutes to obtain the product.

6. Use of the medicinal food composition for improving eyesight, regulating the spleen and enhancing memory according to any one of claims 1 to 4 in the preparation of a medicine for treating liver and kidney deficiency and spleen and stomach deficiency in sub-health conditions.

7. The use according to claim 6, characterized in that The drug has at least one of the following effects: (1) improving the symptoms of dry eyes; (2) improving the symptoms of itchy eyes; (3) improving the symptoms of frequent blinking; (4) improving the symptoms of memory loss; (5) improving the symptoms of forgetfulness; (6) improving the symptoms of dry mouth or dry throat; and (7) improving the symptoms of poor appetite.

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