Raspberry ketone enhanced anti-aging cosmetic formula and preparation process

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to a raspberry ketone enhanced anti-aging cosmetic formula and a preparation process, the raspberry ketone enhanced anti-aging cosmetic formula comprises raspberry ketone and a phospholipid complex (lecithin and diglyceride in a ratio of 3: 1) in a mass ratio of 1: (2-5), 0.5%-2% of sodium hyaluronate and 1%-3% of vitamin E acetate are added, and the pH value of a system is 5.5-6.5. The preparation process comprises the following steps: dissolving raspberry ketone in absolute ethyl alcohol, adding the phospholipid complex, carrying out ultrasonic treatment, carrying out high-pressure homogenization to form a nano-emulsion, and finally adding sodium hyaluronate and vitamin E acetate to adjust the pH value. The stability and permeability of raspberry ketone are improved, the antioxidant capacity is remarkably improved and wrinkles and elasticity are improved by cooperating with multiple active ingredients, and the raspberry ketone composition is suitable for product forms such as face cream and essence, has the characteristics of high stability, excellent permeability and multiple synergistic interaction, and is suitable for large-scale production.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to a raspberry ketone-enhanced anti-aging cosmetic formula and a preparation process. Background Art

[0002] As demand for anti-aging cosmetics continues to grow, consumers are increasingly demanding product efficacy and ingredient innovation. Raspberry ketone, a natural compound with antioxidant, anti-inflammatory, and whitening potential, has gained increasing attention in cosmetics in recent years. However, existing anti-aging cosmetic formulations lack sufficient application of raspberry ketone, particularly in enhancing its stability, permeability, and synergy with other active ingredients, limiting its maximum effectiveness.

[0003] A search revealed that patent publication number CN102085168B discloses an anti-aging cosmetic containing Luremin™ and BIOTIGHTENER and its preparation method. This technology, prepared through an oil-phase and water-phase emulsification process, exhibits significant moisturizing and anti-aging effects. However, the patent does not address the use of raspberry ketones, and the synergistic mechanism of its active ingredients is relatively simple, relying primarily on physical moisturizing and elasticity enhancement, with limited antioxidant and cell repair effects. Furthermore, the formula's stability and permeability still have room for improvement, which may affect the absorption efficiency of the active ingredients deep within the skin.

[0004] Another patent, CN116459189B, proposes an anti-aging composition composed of hydroxypinacolone retinoate, Buddleja buddleja extract, and oligopeptides, which can effectively protect against ultraviolet light and improve skin wrinkles. Although this technical solution performs well in terms of antioxidant and hydration, its formula lacks the use of raspberry ketones, and the compounding system of active ingredients is relatively complex, which may increase the difficulty of the preparation process. At the same time, the long-term effectiveness of this composition in repairing the skin barrier and anti-aging still needs further verification, and there is a possibility that the effect will weaken after a long period of use.

[0005] The above problems indicate that existing anti-aging cosmetics have deficiencies in the application of raspberry ketone and its synergistic effect with other active ingredients. At the same time, there is still room for improvement in formula stability, permeability and long-term effect. Summary of the Invention

[0006] To solve the above problems, the present invention provides a raspberry ketone-enhanced anti-aging cosmetic formula and preparation process, which can not only significantly improve the stability and permeability of raspberry ketone, but also through the synergistic effect of multiple active ingredients, increase the skin's antioxidant capacity by more than 30%, and effectively improve wrinkles and elasticity.

[0007] A raspberry ketone-enhanced anti-aging cosmetic formula comprising, by weight: 0.5%-2% sodium hyaluronate; 1%-3% vitamin E acetate; The rest is raspberry ketone emulsion wrapped by phospholipid complex, and the raspberry ketone emulsion is an oil-in-water structure.

[0008] The above formula contains raspberry ketone and phospholipid complex in a mass ratio of about 1:2-5. The phospholipid complex is composed of lecithin and diglyceride in a mass ratio of 3:1. The pH value of the overall system is 5.5-6.5.

[0009] Preferably, the mass ratio of the raspberry ketone to the phospholipid complex is 1:2-7.

[0010] Preferably, the raspberry ketone emulsion has a droplet size of 100-150 nm and a viscosity of 200-500 mPa·s.

[0011] The raspberry ketone enhanced anti-aging cosmetic formula disclosed in the present invention has obvious distinguishing features compared to the prior art. Raspberry ketone in the prior art usually exists in a single form, has poor stability and is difficult to penetrate into the deep layers of the skin. The present invention, however, encapsulates raspberry ketone by introducing a phospholipid complex to form a nano-scale microparticle structure. This structure can effectively protect raspberry ketone from the influence of the external environment while promoting its penetration into the skin. This solution uses lecithin and diglyceride in the preparation process. These two substances can self-assemble to form a stable double-layer membrane structure. After high-pressure homogenization, they are emulsified to form an emulsion with a particle size of 100-150nm, thereby constructing a uniformly dispersed nanocarrier system, while regulating the water content by the viscosity of the emulsion. In addition, the addition of sodium hyaluronate and vitamin E acetate not only improves the moisturizing performance of the system, but also synergizes with raspberry ketone to exert an antioxidant effect, so that the formula shows stronger long-term anti-aging effect, especially sodium hyaluronate also has the effect of stabilizing viscosity. Therefore, the raspberry ketone-enhanced anti-aging cosmetic formula described in this solution has high stability, excellent permeability, and synergistic effects of multiple active ingredients, providing a comprehensive solution for improving skin aging.

[0012] The core principle of the present invention is to form a nanocarrier through a phospholipid complex, encapsulate raspberry ketone to enhance its stability and skin permeability, and synergize the moisturizing function of sodium hyaluronate with the antioxidant effect of vitamin E acetate to construct a multi-effect anti-aging system. Specifically, the fat-soluble properties of raspberry ketone make it easily soluble in ethanol, and the phospholipid complex self-assembles into 100-150nm nanoemulsion droplets under ultrasound and high-pressure homogenization, forming a double-layer membrane structure to protect raspberry ketone, preventing it from being oxidized, photodegradation, etc., while promoting transdermal absorption. At the same time, by controlling the particle size of nanoemulsions, the irritation that the phospholipid complex may cause to sensitive skin and the risk of skin accumulation of nanoemulsions are prevented; sodium hyaluronate maintains the skin barrier by locking in water, and vitamin E acetate and raspberry ketone jointly scavenge free radicals to enhance overall antioxidant capacity. In the preparation process, high-pressure homogenization and pH adjustment further optimize the uniformity and mildness of the nanoemulsion. In addition, phospholipid complexes may increase the viscosity of the lotion or form a closed film, leading to the risk of acne. Therefore, the viscosity of the lotion must be controlled at 200-500mPa·s. The present invention further discloses a preparation process of the raspberry ketone-enhanced anti-aging cosmetic formula, comprising the following steps: Step (1): dissolving 10-20 parts of raspberry ketone in 50-80 parts of anhydrous ethanol, stirring evenly, adding 30-50 parts of lecithin and 10-20 parts of diglyceride, and ultrasonically treating for 10-30 minutes to obtain a mixed solution; Step (2): adding 100-150 parts of deionized water to the mixed solution obtained in step (1), performing high-pressure homogenization treatment, controlling the pressure to 40-60 MPa, and circulating homogenization 2-4 times to obtain a nanoemulsion; the droplet size of the nanoemulsion is 100-150 nm; and the viscosity is 200-500 mPa·s; Step (3): add 0.5-2 parts of sodium hyaluronate and 1-3 parts of vitamin E acetate to the nanoemulsion obtained in step (2), stir evenly, and then adjust the pH to 5.5-6.5 with citric acid or sodium citrate to obtain a finished product.

[0013] The present invention also discloses the application of the raspberry ketone-enhanced anti-aging cosmetic formula. The formula is applied to the field of anti-aging skin care products, including but not limited to product forms such as face cream, essence and eye cream.

[0014] Compared with the prior art, the present invention has the following advantages: 1. The raspberry ketone-enhanced anti-aging cosmetic formula of the present invention significantly improves the stability and permeability of raspberry ketone through nanocarrier technology. At the same time, combined with the synergistic effect of sodium hyaluronate and vitamin E acetate, it increases the skin's antioxidant capacity by more than 30%, effectively improving wrinkles and elasticity.

[0015] 2. The raw materials of the present invention are widely available, the preparation process is simple and controllable, and it can be adapted to large-scale production. The formula is mild and safe, and is suitable for people with different skin types, providing an innovative solution for the anti-aging cosmetics market. DETAILED DESCRIPTION

[0016] This invention provides a raspberry ketone-enhanced anti-aging cosmetic formula and preparation process. Its core principle is to significantly enhance the stability and permeability of raspberry ketone through nanocarrier technology, and to synergize multiple active ingredients to achieve a highly effective anti-aging effect. The following detailed description of the present invention is based on specific examples to ensure the operability and completeness of the technical solution.

[0017] Example 1

[0018] Step (1): dissolving 15 parts of raspberry ketone in 60 parts of anhydrous ethanol, stirring at room temperature to form a transparent solution, then adding 40 parts of lecithin and 13 parts of diglyceride to the solution, mixing thoroughly, and then ultrasonically treating the solution for 20 minutes using an ultrasonic treatment device, with the ultrasonic frequency set to 20 kHz and the power set to 300 W, to obtain a mixed solution; This step aims to allow lecithin and diglyceride to self-assemble into a stable bilayer membrane structure, while encapsulating raspberry ketones within it to form a preliminary nanoparticle system. During this process, the mass ratio of lecithin to diglyceride is controlled at 3:1. This ratio has been verified through multiple experiments to effectively promote the stability of the bilayer membrane structure and optimize the particle refinement effect during the subsequent emulsification process. Step (2): 120 parts of deionized water were slowly added to the mixed solution obtained in step (1), and homogenized using a high-pressure homogenizer. The homogenization pressure was set to 50 MPa, and the mixture was circulated and homogenized for 3 times, with each homogenization time being 5 minutes. Through high-pressure homogenization, the particle size in the mixture was further refined to 120 nm, and the viscosity of the nanoemulsion was 500 mPa·s. Step (3): Add 1 part of sodium hyaluronate and 2 parts of vitamin E acetate to the nanoemulsion, stir thoroughly to evenly disperse them in the system, and use citric acid solution to adjust the pH value of the system to 5.8 to obtain the finished product.

[0019] Example 2

[0020] Step (1): dissolving 15 parts of raspberry ketone in 60 parts of anhydrous ethanol, stirring at room temperature to form a transparent solution, then adding 40 parts of lecithin and 13 parts of diglyceride to the solution, mixing thoroughly, and then ultrasonically treating the solution for 20 minutes using an ultrasonic treatment device, with the ultrasonic frequency set to 20 kHz and the power set to 300 W; Step (2): 120 parts of deionized water were slowly added to the mixed solution obtained in step (1), and the mixture was homogenized using a high-pressure homogenizer. The homogenization pressure was set to 50 MPa, and the mixture was circulated and homogenized twice, with each homogenization time being 5 minutes. Through high-pressure homogenization, the particle size in the mixture was further refined to 130 nm, and the viscosity of the nanoemulsion was 300 mPa·s. Step (3): Add 1 part of sodium hyaluronate and 2 parts of vitamin E acetate to the nanoemulsion, stir thoroughly to evenly disperse them in the system, and use citric acid solution to adjust the pH value of the system to 5.8 to obtain the finished product.

[0021] Comparative Example 1 The difference from Example 1 is that raspberry ketone is not coated with phospholipid complex: Step (1): dissolving 15 parts of raspberry ketone in 60 parts of anhydrous ethanol, mixing thoroughly, and then ultrasonically treating the mixture for 20 minutes using an ultrasonic treatment device with an ultrasonic frequency set to 20 kHz and a power of 300 W to obtain a mixed solution; Step (2): 120 parts of deionized water were slowly added to the mixed solution obtained in step (1), and homogenized using a high-pressure homogenizer. The homogenization pressure was set to 50 MPa, and the mixture was circulated and homogenized for 3 times, with each homogenization time being 5 minutes. The particle size in the mixture was further refined to 3 μm by high-pressure homogenization, and the dispersion had a viscosity of 200 mPa·s; Step (3): Add 1 part of sodium hyaluronate and 2 parts of vitamin E acetate to the dispersion, stir thoroughly to evenly disperse them in the system, and use citric acid solution to adjust the pH value of the system to 5.8 to obtain the finished product.

[0022] Comparative Example 2 The difference from Example 1 is that the ratio of lecithin to diglyceride is relatively large, and the viscosity is relatively high: Step (1): dissolving 15 parts of raspberry ketone in 60 parts of anhydrous ethanol, stirring at room temperature to form a transparent solution, then adding 60 parts of lecithin and 13 parts of diglyceride to the solution, mixing thoroughly, and then ultrasonically treating the solution for 20 minutes using an ultrasonic treatment device, with the ultrasonic frequency set to 20 kHz and the power set to 300 W, to obtain a mixed solution; Step (2): 120 parts of deionized water were slowly added to the mixed solution obtained in step (1), and homogenized using a high-pressure homogenizer. The homogenization pressure was set to 50 MPa, and the mixture was circulated and homogenized for 3 times, with each homogenization time being 5 minutes. Through high-pressure homogenization, the particle size in the mixture was further refined to 120 nm, and the viscosity of the nanoemulsion was 700 mPa·s. Step (3): Add 1 part of sodium hyaluronate and 2 parts of vitamin E acetate to the nanoemulsion, stir thoroughly to evenly disperse them in the system, and use citric acid solution to adjust the pH value of the system to 5.8 to obtain the finished product.

[0023] Comparative Example 3 The difference from Example 1 is that the particle size of the emulsion droplets is smaller. Step (1): dissolving 15 parts of raspberry ketone in 60 parts of anhydrous ethanol, stirring at room temperature to form a transparent solution, then adding 40 parts of lecithin and 13 parts of diglyceride to the solution, mixing thoroughly, and then ultrasonically treating the solution for 20 minutes using an ultrasonic treatment device, with the ultrasonic frequency set to 20 kHz and the power set to 300 W, to obtain a mixed solution; This step aims to allow lecithin and diglyceride to self-assemble into a stable bilayer membrane structure, while encapsulating raspberry ketones within it to form a preliminary nanoparticle system. During this process, the mass ratio of lecithin to diglyceride is controlled at 3:1. This ratio has been verified through multiple experiments to effectively promote the stability of the bilayer membrane structure and optimize the particle refinement effect during the subsequent emulsification process. Step (2): 120 parts of deionized water were slowly added to the mixed solution obtained in step (1), and homogenized using a high-pressure homogenizer. The homogenization pressure was set to 50 MPa, and the mixture was circulated and homogenized for 3 times, with each homogenization time being 5 minutes. Through high-pressure homogenization, the particle size in the mixture was further refined to 80 nm, and the viscosity of the nanoemulsion was 500 mPa·s. Step (3): Add 1 part of sodium hyaluronate and 2 parts of vitamin E acetate to the nanoemulsion, stir thoroughly to evenly disperse them in the system, and use citric acid solution to adjust the pH value of the system to 5.8 to obtain the finished product.

[0024] Comparative Example 4 The difference from Example 1 is that sodium hyaluronate is replaced by glycerol, and vitamin E acetate is replaced by vitamin E: Step (1): dissolving 15 parts of raspberry ketone in 60 parts of anhydrous ethanol, stirring at room temperature to form a transparent solution, then adding 40 parts of lecithin and 13 parts of diglyceride to the solution, mixing thoroughly, and then ultrasonically treating the solution for 20 minutes using an ultrasonic treatment device, with the ultrasonic frequency set to 20 kHz and the power set to 300 W, to obtain a mixed solution; This step aims to allow lecithin and diglyceride to self-assemble into a stable bilayer membrane structure, while encapsulating raspberry ketones within it to form a preliminary nanoparticle system. During this process, the mass ratio of lecithin to diglyceride is controlled at 3:1. This ratio has been verified through multiple experiments to effectively promote the stability of the bilayer membrane structure and optimize the particle refinement effect during the subsequent emulsification process. Step (2): 120 parts of deionized water were slowly added to the mixed solution obtained in step (1), and homogenized using a high-pressure homogenizer. The homogenization pressure was set to 50 MPa, and the mixture was circulated and homogenized for 3 times, with each homogenization time being 5 minutes. Through high-pressure homogenization, the particle size in the mixture was further refined to 120 nm, and the viscosity of the nanoemulsion was 500 mPa·s. Step (3): Add 1 part of glycerol and 2 parts of vitamin E to the nanoemulsion, stir thoroughly to make them evenly dispersed in the system, and use citric acid solution to adjust the pH value of the system to 5.8 to obtain the finished product.

[0025] Comparative Example 5 The difference from Example 1 is that sodium hyaluronate and vitamin E acetate are added in excess: Step (1): dissolving 15 parts of raspberry ketone in 60 parts of anhydrous ethanol, stirring at room temperature to form a transparent solution, then adding 40 parts of lecithin and 13 parts of diglyceride to the solution, mixing thoroughly, and then ultrasonically treating the solution for 20 minutes using an ultrasonic treatment device, with the ultrasonic frequency set to 20 kHz and the power set to 300 W, to obtain a mixed solution; This step aims to allow lecithin and diglyceride to self-assemble into a stable bilayer membrane structure, while encapsulating raspberry ketones within it to form a preliminary nanoparticle system. During this process, the mass ratio of lecithin to diglyceride is controlled at 3:1. This ratio has been verified through multiple experiments to effectively promote the stability of the bilayer membrane structure and optimize the particle refinement effect during the subsequent emulsification process. Step (2): 120 parts of deionized water were slowly added to the mixed solution obtained in step (1), and homogenized using a high-pressure homogenizer. The homogenization pressure was set to 50 MPa, and the mixture was circulated and homogenized for 3 times, with each homogenization time being 5 minutes. Through high-pressure homogenization, the particle size in the mixture was further refined to 120 nm, and the viscosity of the nanoemulsion was 500 mPa·s. Step (3): Add 3 parts of sodium hyaluronate and 5 parts of vitamin E acetate to the nanoemulsion, stir thoroughly to evenly disperse them in the system, and use citric acid solution to adjust the pH value of the system to 5.8 to obtain the finished product.

[0026] Detection method Particle size and dispersibility: Dynamic light scattering (DLS, Zetasizer Nano ZS90) was used to measure the average droplet size and polydispersity index (PDI). Viscosity: Rotational rheometer (25 °C, shear rate 10 s -1 ); Centrifugal stability: centrifuge at 3000 rpm for 30 minutes and observe the stratification; Hot and cold cycle: -20℃ (12h) and 40℃ (12h) alternately for 7 days; Antioxidant capacity: DPPH free radical scavenging rate (concentration 0.1%, UV spectrophotometry); Moisturizing effect: Corneometer CM825 (horny layer moisture content, 8 hours test); Transdermal absorption rate: Franz diffusion cell (ex vivo pig skin, cumulative permeation of raspberry ketone, 24 hours); Skin irritation: human patch test (30 subjects, occlusive application for 48 hours).

[0027] The test results are shown in Table 1.

[0028] Table 1 sample Particle size (nm) PDI Viscosity (mPa·s) Centrifugal stability Hot and cold cycle stability DPPH clearance rate (%) Moisturizing rate (%) Transdermal absorption rate (%) Irritation (positive rate) Example 1 120 0.12 500 No stratification No demulsification 92.5 78.4 64.3 0% Example 2 130 0.18 300 No stratification Slight flocculation 88.7 75.2 58.1 3.30% Comparative Example 1 3000 0.45 200 Obvious stratification Complete demulsification 52.1 65.8 12.7 6.70% Comparative Example 2 120 0.25 700 No stratification Particle aggregation 85.2 70.3 48.9 10.00% Comparative Example 3 80 0.35 500 Slight delamination Severe demulsification 89.6 76.8 68.5 16.70% Comparative Example 4 120 0.15 480 No stratification No demulsification 73.4 60.2 55.4 0% Comparative Example 5 120 0.3 520 No stratification No demulsification 90.1 79 62.8 23.30% From the comparison of Examples 1-2 and Comparative Examples 1-5, it can be seen that the formula of the present invention achieves a significant anti-aging effect through the synergistic effect of multiple active ingredients. Raspberry ketone, as a powerful antioxidant, can scavenge free radicals and inhibit oxidative stress reactions, thereby delaying skin aging. However, raspberry ketone is easily affected by the external environment and degraded in conventional applications, and it is difficult to penetrate into the deep layers of the skin to exert its effect. The present invention not only improves the stability of raspberry ketone by introducing a phospholipid complex to encapsulate it, but also enhances its penetration ability in the skin. In addition, the addition of sodium hyaluronate and vitamin E acetate further improves the overall performance of the formula. Sodium hyaluronate is a natural moisturizing factor that can form a protective film on the skin surface, lock in moisture and maintain the skin barrier function. Vitamin E acetate has excellent antioxidant properties and can synergize with raspberry ketone to jointly resist damage to the skin from ultraviolet radiation and environmental pollution.

[0029] The preparation process of the present invention is simple and controllable, and is suitable for large-scale production. All raw materials are commercially available products with a wide range of sources and low cost. For example, raspberry ketone can be extracted from natural plants or obtained through chemical synthesis, while lecithin and diglyceride can be purchased through commercial channels. The equipment used in the preparation process, such as ultrasonic processors and high-pressure homogenizers, are common industrial equipment that are simple to operate and easy to maintain. In addition, the pH value of the formula is adjusted in the range of 5.5-6.5, which is close to the natural pH value of human skin. Therefore, it has high safety and is suitable for people with different skin types.

[0030] Comparative Example 1, compared to Example 1, did not use a phospholipid complex to encapsulate raspberry ketone, which directly resulted in the following differences: the particle size increased to 3 μm: the lack of a phospholipid complex prevented the raspberry ketone from being encapsulated by the nanocarrier, and the free molecules aggregated into large particles in the aqueous phase, causing the transdermal absorption rate to drop sharply to 12.7%: large particles (micrometer-sized) were unable to penetrate the stratum corneum, and the free hydrophobic raspberry ketone had difficulty penetrating by passive diffusion. The DPPH scavenging rate decreased to 52.1%: the unencapsulated raspberry ketone was directly exposed to the aqueous phase and was easily oxidized or photolyzed, resulting in degradation of the active ingredient and a decrease in antioxidant capacity. The free raspberry ketone in Comparative Example 1 synergistically stimulated the skin with high-concentration ethanol (60 parts), verifying the necessity of encapsulation technology to reduce irritation.

[0031] In Comparative Example 2, compared with Example 1, the lecithin ratio is too high, causing the viscosity to increase to 700 mPa·s: the excess lecithin forms a dense phospholipid layer, increasing the frictional resistance in the system. At the same time, the free phospholipid molecules thicken, hindering the Brownian motion of the nanoparticles and reducing their contact frequency with the skin. At the same time, the dense phospholipid membrane delays the release of active ingredients. Free lecithin that does not participate in film formation may damage the skin lipid barrier and cause drying irritation. It also undergoes phase change when the temperature changes, destroying the homogeneity of the emulsion, verifying the key influence of the formula ratio on stability.

[0032] Compared to Example 1, the particle size in Comparative Example 3 is too small, which leads to intense Brownian motion and collision aggregation. The PDI rises to 0.35, broadening the particle size distribution. The high surface energy drives the migration of substances from small to large particles, accelerating the emulsion stratification. Furthermore, the ultra-small particles may penetrate into the dermis, activating immune cells and releasing inflammatory factors.

[0033] Comparative Example 4, compared to Example 1, replaces sodium hyaluronate with vitamin E acetate, resulting in significantly weakened functionality: Standard vitamin E (unesterified form) is easily oxidized and inactivated, and lacks charge complementarity with raspberry ketone (esterified vitamin E has lower polarity and is more easily incorporated into the phospholipid bilayer), resulting in a decrease in synergistic antioxidant capacity. Glycerin moisturizes solely through hygroscopic action, while sodium hyaluronate forms a three-dimensional hydration network, resulting in a significant difference in water retention. Furthermore, glycerin lacks the keratin-softening properties of sodium hyaluronate, weakening the penetration-assisting effect of the nanocarrier.

[0034] In Comparative Example 5, compared with Example 1, excessive addition of active ingredients caused side effects, resulting in a surge in irritation. This is because excessive sodium hyaluronate causes local high osmotic pressure, triggering dehydration irritation of the stratum corneum; high concentrations of vitamin E acetate may interfere with the lipid balance of the skin.

[0035] In summary, this invention successfully addresses the poor stability and permeability of raspberry ketone in anti-aging cosmetics through innovative nanocarrier technology and scientific formulation design. The active ingredients in this formulation work synergistically, significantly enhancing the skin's antioxidant capacity and anti-aging effects. Furthermore, the preparation process is simple and efficient, promising promising industrial applications.

Claims

1. A raspberry ketone enhanced anti-aging cosmetic formula, characterized in that: include The proportion by mass includes: 0.5%-2% sodium hyaluronate; 1%-3% vitamin E acetate; The rest is raspberry ketone emulsion wrapped by phospholipid complex, and the raspberry ketone emulsion is an oil-in-water structure.

2. The raspberry ketone enhanced anti-aging cosmetic formula according to claim 1, characterized in that: The mass ratio of the raspberry ketone to the phospholipid complex is 1:2-7.

3. The raspberry ketone enhanced anti-aging cosmetic formula according to claim 1, characterized in that: The raspberry ketone emulsion has an emulsion droplet size of 100-150 nm and a viscosity of 200-500 mPa·s.

4. A process for preparing the raspberry ketone-enhanced anti-aging cosmetic formula according to any one of claims 1 to 3, characterized in that: Calculated by mass, comprising the following steps: Step (1): dissolving 10-20 parts of raspberry ketone in 50-80 parts of anhydrous ethanol, stirring evenly, adding 30-50 parts of lecithin and 10-20 parts of diglyceride, and ultrasonically treating to obtain a mixed solution; Step (2): adding 100-150 parts of deionized water to the mixed solution obtained in step (1), performing high-pressure homogenization treatment, and circulating homogenization 2-4 times to obtain a nanoemulsion; Step (3): Add 0.5-2 parts of sodium hyaluronate and 1-3 parts of vitamin E acetate to the nanoemulsion obtained in step (2), stir evenly, and adjust the pH to 5.5-6.5 to obtain a finished product.

5. The preparation process of the raspberry ketone enhanced anti-aging cosmetic formula according to claim 4, characterized in that: The ultrasonic treatment time in step (1) is 10-30 minutes.

6. The preparation process of the raspberry ketone enhanced anti-aging cosmetic formula according to claim 4, characterized in that: The pressure of the high-pressure homogenization treatment in step (2) is 40-60 MPa.

7. The preparation process of the raspberry ketone enhanced anti-aging cosmetic formula according to claim 4, characterized in that: The droplet size of the nanoemulsion is 100-150 nm.

8. The preparation process of the raspberry ketone enhanced anti-aging cosmetic formula according to claim 4, characterized in that: In the step (2), the viscosity of the nanoemulsion is 200-500 mPa·s.

9. The preparation process of the raspberry ketone enhanced anti-aging cosmetic formula according to claim 4, characterized in that: The reagent for adjusting pH in step (3) is citric acid or sodium citrate solution.

10. A raspberry ketone-enhanced anti-aging cosmetic formula according to any one of claims 1 to 3, applied to anti-aging skin care products, including face creams, essences, and eye creams.