Hemodialysis device

Abstract

The invention discloses a hemodialysis device which comprises a dialyzer, an artery blood circulation catheter, a vein blood circulation catheter, a dialysate supply mechanism, a dialysate input catheter, a dialysate collection mechanism and a dialysate output catheter, and the dialysate supply mechanism comprises a dialysate supply box, a dialysate mixing pipe, a concentrated dialysate box and a dialysis water box. The dialysate mixing pipe is connected with a three-way pipe, a concentrated dialysate guide pipe is connected between one input end of the three-way pipe and the concentrated dialysate box, a first adjusting pump is arranged on the concentrated dialysate guide pipe, and the first adjusting pump is connected with a controller; a dialysis water guide pipe is connected between the other input end of the three-way pipe and the dialysis water tank, a second adjusting pump is arranged on the dialysis water guide pipe, and the second adjusting pump is connected with the controller. The potassium ion change in the dialysate can be adjusted in the hemodialysis treatment process, the hemodialysis treatment effect is improved, and the possibility of complications of patients is reduced.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical devices, and in particular relates to a hemodialysis device. Background Art

[0002] Hemodialysis clinically refers to the removal of waste products from the blood through a semipermeable membrane. It is one of the safest, easiest, and most widely used blood purification methods. Dialysis involves the movement of solutes through a semipermeable membrane, from a high-concentration solution to a low-concentration solution. Hemodialysis involves both solute and water movement. Specifically, blood and dialysate exchange substances within the dialyzer (artificial kidney) via the contact of the semipermeable membrane and the concentration gradient. This allows metabolic waste products and excess electrolytes in the blood to move into the dialysate, while calcium ions and bases in the dialysate move into the blood. If a mixture of albumin and urea is placed in the dialyzer and the outside of the tubing is soaked in water, the urea in the dialyzer tubing will migrate through the pores of the artificial kidney membrane into the water outside the tubing. Albumin molecules are larger and cannot pass through the pores. This phenomenon of mass movement, where small molecules can pass through the semipermeable membrane but larger molecules cannot, is called diffusion. The clinical use of diffusion to separate and purify blood for purification purposes is the fundamental principle of hemodialysis.

[0003] Dialysis-associated arrhythmias are common complications in hemodialysis patients, with atrial fibrillation and ventricular arrhythmias being the most common. These conditions often interfere with the normal progress of dialysis. Hypokalemia during dialysis is a possible cause. Potassium is a key electrolyte in the human body, serving as the primary intracellular cation and essential for the electrophysiological activity of cardiomyocytes. Normal potassium levels are essential for maintaining cardiac electrophysiological activity. Most uremic patients have hyperkalemia before dialysis. Severe hyperkalemia can easily lead to cardiac arrest or even sudden death. However, during dialysis, as potassium ions are cleared through the dialyzer membrane and acidosis corrects, potassium ions enter the cells from outside the body, further lowering serum potassium. This can lead to abnormal myocardial repolarization and induce arrhythmias. This is more common in elderly patients and those with underlying heart disease. Hypokalemia-related arrhythmias often occur in the early stages of dialysis, when the difference between the potassium concentration in the dialysate and the serum potassium concentration is large, making arrhythmias more likely to occur. As dialysis treatment continues, potassium removal increases, the gradient between dialysate potassium and blood potassium concentrations decreases, and the risk of arrhythmias decreases. Therefore, it is crucial to continuously adjust the potassium concentration of the dialysate during treatment.

[0004] Currently, all hemodialysis devices on the market do not have a dialysate concentration adjustment function, resulting in an unadjustable potassium concentration. Therefore, it is necessary to develop a new hemodialysis device to solve the above technical problems existing in the prior art. Summary of the Invention

[0005] The purpose of the present invention is to provide a hemodialysis device to solve the above-mentioned problems existing in the prior art.

[0006] In order to achieve the above-mentioned object, the present invention adopts the following technical solution: a hemodialysis device, comprising a dialyzer, an arterial blood circulation conduit, a venous blood circulation conduit, a dialysate supply mechanism, a dialysate input conduit, a dialysate collection mechanism and a dialysate output conduit, wherein the dialyzer is provided with a blood inlet, a blood outlet, a dialysate inlet and a dialysate outlet, wherein the blood inlet is connected to the arterial blood circulation conduit, and the blood outlet is connected to the venous blood circulation conduit; the dialysate inlet is connected to the dialysate supply mechanism via the dialysate input conduit, and the dialysate outlet is connected to the dialysate collection mechanism via the dialysate output conduit; ... The liquid supply mechanism includes a dialysate supply box, a dialysate mixing tube, a concentrated dialysate box and a dialysis water tank. The output end of the dialysate supply box is connected to the dialysate input conduit, and the input end of the dialysate supply box is connected to the output end of the dialysate mixing tube. The dialysate mixing tube is connected to a tee. A concentrated dialysate conduit is connected between one input end of the tee and the concentrated dialysate box. A first regulating pump is provided on the concentrated dialysate conduit, and the first regulating pump is connected to a controller. A dialysis water conduit is connected between the other input end of the tee and the dialysis water tank. A second regulating pump is provided on the dialysis water conduit, and the second regulating pump is connected to the controller.

[0007] As an optional implementation of the above technical solution, the dialysate mixing tube includes a mixing tube body, an upper conduit and a lower conduit are provided on the mixing tube body, a filter plate is provided inside the mixing tube body, a rotating shaft is provided on the filter plate for rotation, a breaking and mixing mechanism is provided at one end of the rotating shaft close to the upper conduit, and a stirring mechanism is provided at one end of the rotating shaft close to the lower conduit.

[0008] As an optional implementation of the above technical solution, the breaking up and mixing mechanism includes multiple layers of breaking up components, each layer of the breaking up components includes multiple breaking up bars, and the multiple breaking up bars are arranged in a ring shape on the rotating shaft.

[0009] As an optional implementation of the above technical solution, the breaking strip is arranged obliquely on the rotating shaft.

[0010] As an optional implementation of the above technical solution, the breaking up bars of the upper breaking up assembly and the breaking up bars of the lower breaking up assembly are staggered.

[0011] As an optional implementation of the above technical solution, a guide cone is provided at the end of the rotating shaft, and the guide cone faces the upper conduit.

[0012] As an optional implementation of the above technical solution, the stirring mechanism includes multiple layers of stirring components, each layer of stirring components includes multiple stirring bars, and the multiple stirring bars are arranged in a ring shape on the rotating shaft.

[0013] As an optional implementation of the above technical solution, the stirring bars of the upper stirring assembly and the stirring bars of the lower stirring assembly are staggered.

[0014] As an optional implementation of the above technical solution, the dialyzer includes a dialysis shell, the blood inlet is arranged at the top of the dialysis shell, the blood outlet is arranged at the bottom of the dialysis shell, and the dialysate inlet and the dialysate outlet are arranged on the side wall of the dialysis shell; a dialysis chamber, a blood temporary storage bin and a blood collection bin are provided inside the dialysis shell, the blood temporary storage bin is connected to the blood inlet, the blood collection bin is connected to the blood outlet, and the dialysate inlet and the dialysate outlet are both connected to the dialysis chamber; a plurality of hollow fiber tubes are provided in the dialysis chamber, and the two ends of the hollow fiber tubes are respectively connected to the blood temporary storage bin and the blood collection bin.

[0015] As an optional implementation of the above technical solution, the arterial blood circulation catheter is provided with a blood pump and a first sampling tube, the first sampling tube is provided with a first pressure detection mechanism, and the end of the first sampling tube is provided with a first sampling port.

[0016] As an optional implementation of the above technical solution, the venous blood circulation catheter is provided with a second sampling tube, the second sampling tube is provided with a second pressure detection mechanism, and the end of the second sampling tube is provided with a second sampling port.

[0017] As an optional implementation of the above technical solution, the dialysate inlet conduit is provided with a dialysate pump, a first heater and a first temperature sensor; the venous blood circulation conduit is provided with a second heater, a second temperature sensor and a third temperature sensor, and the first heater, the first temperature sensor, the second heater, the second temperature sensor and the third temperature sensor are all connected to a controller; the second temperature sensor and the third temperature sensor are respectively arranged at both ends of the dialysate inlet conduit, and the controller is used to regulate the heating power of the first heater based on the detection temperatures of the first temperature sensor and the second temperature sensor, and to regulate the heating power of the second heater based on the detection temperatures of the second temperature sensor and the third temperature sensor.

[0018] As an optional implementation of the above technical solution, a mixed liquid conduit is connected between the dialysate mixing tube and the dialysate supply box.

[0019] The beneficial effects of the present invention are:

[0020] The present invention provides a hemodialysis device, comprising a first regulating pump provided on a concentrated dialysate conduit, the first regulating pump being connected to a controller; and a second regulating pump provided on a dialysate water conduit, the second regulating pump being connected to the controller. The controller, through the first and second regulating pumps, adjusts the pumping ratio of concentrated dialysate to dialysate water, thereby regulating the potassium ion concentration of the mixed solution and preventing dialysis-related arrhythmias. The present invention can regulate potassium ion changes in the dialysate during hemodialysis treatment, improving the effectiveness of hemodialysis treatment and reducing the likelihood of complications for patients. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 is a schematic structural diagram of a hemodialysis device in one embodiment of the present invention;

[0022] Figure 2 1 is a schematic structural diagram of a dialyzer according to one embodiment of the present invention;

[0023] Figure 3 is a structural schematic diagram of a dialysate supply mechanism in one embodiment of the present invention;

[0024] Figure 4 Schematic diagram of the structure of a dialysate mixing tube in one embodiment of the present invention;

[0025] Figure 5 It is a schematic structural diagram of a breaking strip in one embodiment of the present invention.

[0026] In the figure: 1-dialyzer; 2-arterial blood circulation catheter; 3-venous blood circulation catheter; 4-dialysate supply mechanism; 5-dialysate input catheter; 6-dialysate collection mechanism; 7-dialysate output catheter; 8-blood inlet; 9-blood outlet; 10-dialysate inlet; 11-dialysate outlet; 12-dialysate supply tank; 13-dialysate mixing tube; 14-concentrated dialysate tank; 15-dialysis water tank; 16-first regulating pump; 17-second regulating pump; 18-mixing tube body; 19-upper catheter; 20-lower catheter; 21-filter plate; 22-rotating shaft; 23-dispersing and mixing mechanism; 24-stirring mechanism; 25-dispersing bar; 26-dialysis shell; 27-dialysis chamber; 28-blood temporary storage bin; 29-blood collection bin; 30-hollow fiber tube; 31-blood pump; 32-first sampling tube; 33-first pressure detection mechanism; 34-second sampling tube; 35-second pressure detection mechanism; 36-dialysate pump; 37-first heater; 38-second heater. DETAILED DESCRIPTION

[0027] Example 1

[0028] like Figure 1 and Figure 2As shown, this embodiment provides a hemodialysis device, including a dialyzer 1, an arterial blood circulation conduit 2, a venous blood circulation conduit 3, a dialysate supply mechanism 4, a dialysate input conduit 5, a dialysate collection mechanism 6, and a dialysate output conduit 7. The dialyzer 1 is provided with a blood inlet 8, a blood outlet 9, a dialysate inlet 10, and a dialysate outlet 11. The blood inlet 8 is connected to the arterial blood circulation conduit 2, and the blood outlet 9 is connected to the venous blood circulation conduit 3. The dialysate inlet 10 is connected to the dialysate supply mechanism 4 via the dialysate input conduit 5, and the dialysate outlet 11 is connected to the dialysate collection mechanism 6 via the dialysate output conduit 7. The arterial blood circulation conduit 2 introduces human blood into the dialyzer 1. After the dialyzer 1 filters the blood, it is delivered to the human body through the venous blood circulation conduit 3. The dialysate supply mechanism 4 provides dialysate containing potassium ions to the dialyzer 1 . After the dialysate enters the dialyzer 1 , it takes away metabolic waste and excess electrolytes in the blood, and is then transported to the dialysate collection mechanism 6 through the dialysate output conduit 7 .

[0029] The dialysate supply mechanism 4 includes a dialysate supply tank 12, a dialysate mixing tube 13, a concentrated dialysate tank 14, and a dialysis water tank 15. The output end of the dialysate supply tank 12 is connected to the dialysate input conduit 5, and the input end of the dialysate supply tank 12 is connected to the output end of the dialysate mixing tube 13. Specifically, a mixed liquid conduit is connected between the dialysate mixing tube 13 and the dialysate supply tank 12. The dialysate mixing tube 13 is connected to a tee pipe, one input end of which is connected to a concentrated dialysate conduit, and a first regulating pump 16 is provided on the concentrated dialysate conduit, which is connected to a controller. The other input end of the tee pipe is connected to the dialysis water tank 15, and a second regulating pump 17 is provided on the dialysis water conduit, which is connected to a controller. The concentrated dialysate tank 14 stores concentrated dialysate, which primarily contains sodium chloride, potassium chloride, calcium chloride, magnesium chloride, and glucose, and is diluted with dialysate water. A controller, via a first regulating pump 16 and a second regulating pump 17, adjusts the pumping ratio of the concentrated dialysate to the dialysate water, thereby regulating the potassium ion concentration of the mixed solution and preventing dialysis-related arrhythmias.

[0030] The present invention can adjust the change of potassium ions in the dialysate during the hemodialysis treatment process, improve the hemodialysis treatment effect, and reduce the possibility of complications in patients.

[0031] Example 2

[0032] This embodiment is optimized based on embodiment 1. Specifically, Figure 4As shown, the dialysate mixing tube 13 includes a mixing tube body 18, which is provided with an upper conduit 19 and a lower conduit 20. A filter plate 21 is located within the mixing tube body 18. A rotating shaft 22 is rotatably mounted on the filter plate 21. The end of the rotating shaft 22 near the upper conduit 19 is provided with a dispersing and mixing mechanism 23, and the end of the rotating shaft 22 near the lower conduit 20 is provided with a stirring mechanism 24. The distal end of the rotating shaft 22 is provided with a guide cone, which faces the upper conduit 19. Under the impact of the concentrated dialysate and dialysate water, the dispersing and mixing mechanism 23 rotates, dispersing the concentrated dialysate and dialysate water, facilitating their uniform mixing. The concentrated dialysate and dialysate water pass through the pores of the filter plate 21 and enter the space below the filter plate 21. The stirring mechanism 24 rotates and stirs the concentrated dialysate and dialysate water, ensuring thorough mixing.

[0033] Specifically, the breaking up and mixing mechanism 23 includes multiple layers of breaking up components, and each layer of breaking up components includes multiple breaking up bars 25, and multiple breaking up bars 25 are arranged in a ring shape on the rotating shaft 22. Preferably, the breaking up bars 25 are arranged obliquely on the rotating shaft 22. Furthermore, the breaking up bars 25 of the upper layer breaking up components and the breaking up bars 25 of the lower layer breaking up components are staggered. The present invention makes full use of the kinetic energy of the concentrated dialysate and the dialysate water to achieve the breaking up and stirring functions of the concentrated dialysate and the dialysate water, and its use is more energy-efficient. It should be noted that if the flow rate of the concentrated dialysate and the dialysate water is low, it can be driven by adding a motor to the rotating shaft 22.

[0034] The stirring mechanism 24 includes multiple layers of stirring assemblies, each layer of which includes multiple stirring bars arranged in a ring shape on the rotating shaft 22. The stirring bars of the upper stirring assembly are staggered with the stirring bars of the lower stirring assembly to improve the stirring effect of the concentrated dialysate and the dialysate water, thereby ensuring uniform mixing of the concentrated dialysate and the dialysate water.

[0035] Example 3

[0036] This embodiment is optimized based on embodiment 1. Specifically, Figure 2 As shown, the dialyzer 1 includes a dialysis shell 26, the blood inlet 8 is provided at the top of the dialysis shell 26, the blood outlet 9 is provided at the bottom of the dialysis shell 26, and the dialysate inlet 10 and the dialysate outlet 11 are provided on the side wall of the dialysis shell 26; a dialysis chamber 27, a blood temporary storage bin 28 and a blood collection bin 29 are provided inside the dialysis shell 26, the blood temporary storage bin 28 is connected to the blood inlet 8, the blood collection bin 29 is connected to the blood outlet 9, and the dialysate inlet 10 and the dialysate outlet 11 are both connected to the dialysis chamber 27; a plurality of hollow fiber tubes 30 are provided in the dialysis chamber 27, and the two ends of the hollow fiber tubes 30 are respectively connected to the blood temporary storage bin 28 and the blood collection bin 29.

[0037] The present invention sets a blood temporary storage chamber 28 and a blood collection chamber 29 inside the dialysis shell 26. On the one hand, the arterial blood is fully dispersed into each hollow fiber tube 30 in the blood temporary storage chamber 28, and on the other hand, it is collected in the blood collection chamber 29, thereby effectively ensuring the blood flow returned to the patient's body. In addition, the hollow fiber tube 30 structure can fully increase the contact area between blood and dialysate, effectively improving the dialysis efficiency of blood.

[0038] Example 4

[0039] This embodiment is optimized based on embodiment 1. Specifically, Figure 1 As shown, the arterial blood circulation catheter 2 is equipped with a blood pump 31 and a first sampling tube 32. The first sampling tube 32 is equipped with a first pressure detection mechanism 33, and a first sampling port is provided at the end of the first sampling tube 32. The venous blood circulation catheter 3 is equipped with a second sampling tube 34. The second sampling tube 34 is equipped with a second pressure detection mechanism 35, and a second sampling port is provided at the end of the second sampling tube 34. Blood is sampled through the first sampling port and the second sampling tube 34 to determine changes in potassium ion concentration and other parameters in the blood.

[0040] The dialysate inlet conduit 5 is provided with a dialysate pump 36, a first heater 37 and a first temperature sensor; the venous blood circulation conduit 3 is provided with a second heater 38, a second temperature sensor and a third temperature sensor, and the first heater 37, the first temperature sensor, the second heater 38, the second temperature sensor and the third temperature sensor are all connected to a controller; the second temperature sensor and the third temperature sensor are respectively arranged at both ends of the dialysate inlet conduit 5, and the controller is used to regulate the heating power of the first heater 37 based on the detection temperatures of the first temperature sensor and the second temperature sensor, and to regulate the heating power of the second heater 38 based on the detection temperatures of the second temperature sensor and the third temperature sensor.

[0041] The first heater 37 heats the dialysate to maintain a suitable temperature. The heated dialysate enters the dialyzer 1 to exchange heat with the blood, raising the blood temperature. When the blood is output from the dialyzer 1, the second temperature sensor detects the temperature of the blood. The controller regulates the heating power of the first heater 37 based on the detected temperatures of the first temperature sensor and the second temperature sensor, so that the blood output from the dialyzer 1 remains within a suitable temperature range. When the blood is about to be delivered to the human body, the third temperature sensor detects the temperature of the blood. The controller regulates the heating power of the second heater 38 based on the detected temperatures of the second temperature sensor and the third temperature sensor, so that the blood maintains a suitable temperature before entering the human body. The present invention controls the blood temperature during the hemodialysis process through two temperature controls, thereby maintaining a balance between heat generation and heat dissipation during hemodialysis and preventing blood of unqualified temperature from flowing back into the patient's body.

[0042] Example 5

[0043] like Figure 1-Figure 5 As shown, this embodiment provides a hemodialysis device, including a dialyzer 1, an arterial blood circulation conduit 2, a venous blood circulation conduit 3, a dialysate supply mechanism 4, a dialysate input conduit 5, a dialysate collection mechanism 6, and a dialysate output conduit 7. The dialyzer 1 is provided with a blood inlet 8, a blood outlet 9, a dialysate inlet 10, and a dialysate outlet 11. The blood inlet 8 is connected to the arterial blood circulation conduit 2, and the blood outlet 9 is connected to the venous blood circulation conduit 3. The dialysate inlet 10 is connected to the dialysate supply mechanism 4 via the dialysate input conduit 5, and the dialysate outlet 11 is connected to the dialysate collection mechanism 6 via the dialysate output conduit 7. The arterial blood circulation conduit 2 introduces human blood into the dialyzer 1. After the dialyzer 1 filters the blood, it is delivered to the human body through the venous blood circulation conduit 3. The dialysate supply mechanism 4 provides dialysate containing potassium ions to the dialyzer 1 . After the dialysate enters the dialyzer 1 , it takes away metabolic waste and excess electrolytes in the blood, and is then transported to the dialysate collection mechanism 6 through the dialysate output conduit 7 .

[0044] The dialysate supply mechanism 4 includes a dialysate supply tank 12, a dialysate mixing tube 13, a concentrated dialysate tank 14, and a dialysis water tank 15. The output end of the dialysate supply tank 12 is connected to the dialysate input conduit 5, and the input end of the dialysate supply tank 12 is connected to the output end of the dialysate mixing tube 13. Specifically, a mixed liquid conduit is connected between the dialysate mixing tube 13 and the dialysate supply tank 12. The dialysate mixing tube 13 is connected to a tee pipe, one input end of which is connected to a concentrated dialysate conduit, and a first regulating pump 16 is provided on the concentrated dialysate conduit, which is connected to a controller. The other input end of the tee pipe is connected to the dialysis water tank 15, and a second regulating pump 17 is provided on the dialysis water conduit, which is connected to a controller. The concentrated dialysate tank 14 stores concentrated dialysate, which primarily contains sodium chloride, potassium chloride, calcium chloride, magnesium chloride, and glucose, and is diluted with dialysate water. A controller, via a first regulating pump 16 and a second regulating pump 17, adjusts the pumping ratio of the concentrated dialysate to the dialysate water, thereby regulating the potassium ion concentration of the mixed solution and preventing dialysis-related arrhythmias.

[0045] The present invention can adjust the change of potassium ions in the dialysate during the hemodialysis treatment process, improve the hemodialysis treatment effect, and reduce the possibility of complications in patients.

[0046] In this embodiment, the dialysate mixing tube 13 includes a mixing tube body 18, which is provided with an upper conduit 19 and a lower conduit 20. A filter plate 21 is located within the mixing tube body 18. A rotating shaft 22 is rotatably mounted on the filter plate 21. The end of the rotating shaft 22 near the upper conduit 19 is provided with a dispersing and mixing mechanism 23, and the end of the rotating shaft 22 near the lower conduit 20 is provided with a stirring mechanism 24. The distal end of the rotating shaft 22 is provided with a guide cone, which faces the upper conduit 19. Under the impact of the concentrated dialysate and dialysate water, the dispersing and mixing mechanism 23 rotates, dispersing the concentrated dialysate and dialysate water, facilitating their uniform mixing. The concentrated dialysate and dialysate water pass through the pores of the filter plate 21 and enter the space below the filter plate 21. The stirring mechanism 24 rotates and stirs the concentrated dialysate and dialysate water, ensuring thorough mixing.

[0047] Specifically, the breaking up and mixing mechanism 23 includes multiple layers of breaking up components, and each layer of breaking up components includes multiple breaking up bars 25, and multiple breaking up bars 25 are arranged in a ring shape on the rotating shaft 22. Preferably, the breaking up bars 25 are arranged obliquely on the rotating shaft 22. Furthermore, the breaking up bars 25 of the upper layer breaking up components and the breaking up bars 25 of the lower layer breaking up components are staggered. The present invention makes full use of the kinetic energy of the concentrated dialysate and the dialysate water to achieve the breaking up and stirring functions of the concentrated dialysate and the dialysate water, and its use is more energy-efficient. It should be noted that if the flow rate of the concentrated dialysate and the dialysate water is low, it can be driven by adding a motor to the rotating shaft 22.

[0048] The stirring mechanism 24 includes multiple layers of stirring assemblies, each layer of which includes multiple stirring bars arranged in a ring shape on the rotating shaft 22. The stirring bars of the upper stirring assembly are staggered with the stirring bars of the lower stirring assembly to improve the stirring effect of the concentrated dialysate and the dialysate water, thereby ensuring uniform mixing of the concentrated dialysate and the dialysate water.

[0049] In this embodiment, the dialyzer 1 includes a dialysis shell 26, the blood inlet 8 is provided at the top of the dialysis shell 26, the blood outlet 9 is provided at the bottom of the dialysis shell 26, and the dialysate inlet 10 and the dialysate outlet 11 are provided on the side wall of the dialysis shell 26; a dialysis chamber 27, a blood temporary storage bin 28 and a blood collection bin 29 are provided inside the dialysis shell 26, the blood temporary storage bin 28 is connected to the blood inlet 8, the blood collection bin 29 is connected to the blood outlet 9, and the dialysate inlet 10 and the dialysate outlet 11 are both connected to the dialysis chamber 27; a plurality of hollow fiber tubes 30 are provided in the dialysis chamber 27, and the two ends of the hollow fiber tubes 30 are respectively connected to the blood temporary storage bin 28 and the blood collection bin 29.

[0050] The present invention sets a blood temporary storage chamber 28 and a blood collection chamber 29 inside the dialysis shell 26. On the one hand, the arterial blood is fully dispersed into each hollow fiber tube 30 in the blood temporary storage chamber 28, and on the other hand, it is collected in the blood collection chamber 29, thereby effectively ensuring the blood flow returned to the patient's body. In addition, the hollow fiber tube 30 structure can fully increase the contact area between blood and dialysate, effectively improving the dialysis efficiency of blood.

[0051] In this embodiment, the arterial blood circulation catheter 2 is equipped with a blood pump 31 and a first sampling tube 32. The first sampling tube 32 is equipped with a first pressure detection mechanism 33, and a first sampling port is provided at the end of the first sampling tube 32. The venous blood circulation catheter 3 is equipped with a second sampling tube 34. The second sampling tube 34 is equipped with a second pressure detection mechanism 35, and a second sampling port is provided at the end of the second sampling tube 34. Blood is sampled through the first sampling port and the second sampling tube 34 to determine changes in potassium ion concentration and other parameters in the blood.

[0052] In this embodiment, the dialysate inlet conduit 5 is provided with a dialysate pump 36, a first heater 37 and a first temperature sensor; the venous blood circulation conduit 3 is provided with a second heater 38, a second temperature sensor and a third temperature sensor, and the first heater 37, the first temperature sensor, the second heater 38, the second temperature sensor and the third temperature sensor are all connected to a controller; the second temperature sensor and the third temperature sensor are respectively arranged at both ends of the dialysate inlet conduit 5, and the controller is used to regulate the heating power of the first heater 37 based on the detection temperatures of the first temperature sensor and the second temperature sensor, and to regulate the heating power of the second heater 38 based on the detection temperatures of the second temperature sensor and the third temperature sensor.

[0053] The first heater 37 heats the dialysate to maintain a suitable temperature. The heated dialysate enters the dialyzer 1 to exchange heat with the blood, raising the blood temperature. When the blood is output from the dialyzer 1, the second temperature sensor detects the temperature of the blood. The controller regulates the heating power of the first heater 37 based on the detected temperatures of the first temperature sensor and the second temperature sensor, so that the blood output from the dialyzer 1 remains within a suitable temperature range. When the blood is about to be delivered to the human body, the third temperature sensor detects the temperature of the blood. The controller regulates the heating power of the second heater 38 based on the detected temperatures of the second temperature sensor and the third temperature sensor, so that the blood maintains a suitable temperature before entering the human body. The present invention controls the blood temperature during the hemodialysis process through two temperature controls, thereby maintaining a balance between heat generation and heat dissipation during hemodialysis and preventing blood of unqualified temperature from flowing back into the patient's body.

[0054] In the description of the present invention, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, and may be fixedly connected, detachably connected, or integrated; may be mechanically connected or electrically connected; may be directly connected or indirectly connected through an intermediate medium; may be internal connectivity between two elements or an interaction relationship between two elements. Those skilled in the art can understand the specific meanings of the above terms in the present invention. In addition, the specific features, structures, etc. described in the embodiments are included in at least one embodiment. Under the condition that there is no contradiction, those skilled in the art may combine the features of different embodiments. The scope of protection of the present invention is not limited to the above-mentioned specific embodiments. According to the basic technical concept of the present invention, the embodiments that can be associated with by ordinary technicians in this field without creative work all fall within the scope of protection of the present invention.

Claims

1. A hemodialysis device, characterized in that: The dialyzer (1) comprises a dialyzer (1), an arterial blood circulation conduit (2), a venous blood circulation conduit (3), a dialysate supply mechanism (4), a dialysate input conduit (5), a dialysate collection mechanism (6) and a dialysate output conduit (7). The dialyzer (1) is provided with a blood inlet (8), a blood outlet (9), a dialysate inlet (10) and a dialysate outlet (11). The blood inlet (8) is in communication with the arterial blood circulation conduit (2), and the blood outlet (9) is in communication with the venous blood circulation conduit (3); the dialysate inlet (10) is in communication with the dialysate supply mechanism (4) via the dialysate input conduit (5), and the dialysate outlet (11) is in communication with the dialysate collection mechanism (6) via the dialysate output conduit (7); the dialysate supply mechanism (4) comprises a dialysate inlet (8), a blood outlet (9), a dialysate inlet (10) and a dialysate outlet (11). A dialysate supply box (12), a dialysate mixing tube (13), a concentrated dialysate box (14) and a dialysate water tank (15); the output end of the dialysate supply box (12) is connected to the dialysate input conduit (5); the input end of the dialysate supply box (12) is connected to the output end of the dialysate mixing tube (13); the dialysate mixing tube (13) is connected to a tee; a concentrated dialysate conduit is connected between one input end of the tee and the concentrated dialysate box (14); a first regulating pump (16) is provided on the concentrated dialysate conduit; the first regulating pump (16) is connected to a controller; a dialysate water conduit is connected between the other input end of the tee and the dialysate water tank (15); a second regulating pump (17) is provided on the dialysate water conduit; the second regulating pump (17) is connected to the controller.

2. The hemodialysis device according to claim 1, characterized in that The dialysate mixing tube (13) comprises a mixing tube body (18), an upper conduit (19) and a lower conduit (20) are provided on the mixing tube body (18), a filter plate (21) is provided inside the mixing tube body (18), a rotating shaft (22) is rotatably provided on the filter plate (21), a breaking and mixing mechanism (23) is provided at one end of the rotating shaft (22) close to the upper conduit (19), and a stirring mechanism (24) is provided at one end of the rotating shaft (22) close to the lower conduit (20).

3. The hemodialysis device according to claim 2, characterized in that The dispersing and mixing mechanism (23) comprises multiple layers of dispersing components, each layer of the dispersing components comprises multiple dispersing bars (25), and the multiple dispersing bars (25) are arranged in a ring shape on the rotating shaft (22).

4. The hemodialysis device according to claim 3, characterized in that The breaking strip (25) is tiltedly arranged on the rotating shaft (22).

5. The hemodialysis device according to claim 2, characterized in that The breaking-up bars (25) of the upper breaking-up assembly and the breaking-up bars (25) of the lower breaking-up assembly are arranged in a staggered manner.

6. The hemodialysis device according to claim 5, characterized in that A guide cone is provided at the end of the rotating shaft (22), and the guide cone faces the upper conduit (19).

7. The hemodialysis device according to claim 2, characterized in that The stirring mechanism (24) includes multiple layers of stirring components, each layer of stirring components includes multiple stirring bars, and the multiple stirring bars are arranged in a ring shape on the rotating shaft (22); the stirring bars of the upper layer stirring component and the stirring bars of the lower layer stirring component are staggered.

8. The hemodialysis device according to claim 1, characterized in that The dialyzer (1) comprises a dialysis shell (26), wherein the blood inlet (8) is arranged at the top of the dialysis shell (26), the blood outlet (9) is arranged at the bottom of the dialysis shell (26), and the dialysate inlet (10) and the dialysate outlet (11) are arranged on the side wall of the dialysis shell (26); a dialysis chamber (27), a blood temporary storage bin (28) and a blood collection bin (29) are arranged inside the dialysis shell (26), wherein the blood temporary storage bin (28) is communicated with the blood inlet (8), the blood collection bin (29) is communicated with the blood outlet (9), and the dialysate inlet (10) and the dialysate outlet (11) are both communicated with the dialysis chamber (27); a plurality of hollow fiber tubes (30) are arranged in the dialysis chamber (27), and the two ends of the hollow fiber tubes (30) are respectively communicated with the blood temporary storage bin (28) and the blood collection bin (29).

9. The hemodialysis device according to claim 1, characterized in that The arterial blood circulation conduit (2) is provided with a blood pump (31) and a first sampling tube (32), the first sampling tube (32) is provided with a first pressure detection mechanism (33), and the end of the first sampling tube (32) is provided with a first sampling port; the venous blood circulation conduit (3) is provided with a second sampling tube (34), the second sampling tube (34) is provided with a second pressure detection mechanism (35), and the end of the second sampling tube (34) is provided with a second sampling port.

10. The hemodialysis device according to claim 1, characterized in that The dialysate input conduit (5) is provided with a dialysate pump (36), a first heater (37) and a first temperature sensor; the venous blood circulation conduit (3) is provided with a second heater (38), a second temperature sensor and a third temperature sensor, and the first heater (37), the first temperature sensor, the second heater (38), the second temperature sensor and the third temperature sensor are all connected to a controller; the second temperature sensor and the third temperature sensor are respectively provided at both ends of the dialysate input conduit (5), and the controller is used to regulate the heating power of the first heater (37) based on the detection temperatures of the first temperature sensor and the second temperature sensor, and to regulate the heating power of the second heater (38) based on the detection temperatures of the second temperature sensor and the third temperature sensor.

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