Microwave ablation system and control method thereof

Abstract

The invention provides a microwave ablation system and a control method thereof. The microwave ablation system comprises a liquid injection mechanism, an acquisition unit and an adjustment control unit, wherein the acquisition unit is used for acquiring standing-wave ratio parameters of the microwave ablation system in a microwave ablation process; the processing unit is electrically connected with the acquisition sensor and the adjustment control unit, and is used for sending a parameter adjustment control signal to the adjustment control unit when the standing-wave ratio parameter acquired by the acquisition unit exceeds a first set threshold range; the adjustment control unit is electrically connected with the acquisition unit, the processing unit and the liquid injection mechanism and is used for starting a closed-loop control program after receiving the parameter adjustment control signal, adjusting the flow of a fluid medium conveyed to the target tissue by the liquid injection mechanism in the microwave ablation process according to the standing-wave ratio parameter acquired by the acquisition unit, and adjusting the flow of the fluid medium to the target tissue. Enabling the standing-wave ratio parameter to fall into a second set threshold range; the first set threshold range is larger than the second set threshold range. The safety in the microwave ablation process can be improved.

Description

Technical Field

[0001] The present application relates to the technical field of microwave ablation, and in particular, to a microwave ablation system and a control method thereof. Background Art

[0002] Cancer is a common, age-old disease that poses a serious threat to human health. Developing effective tumor treatments has long been a goal of clinical medicine. With the rapid development of tumor hyperthermia technology, microwave ablation, with its minimally invasive, effective, simple, and relatively low-cost advantages, has gained widespread application and has become a leading hyperthermia treatment option.

[0003] Among them, how to ensure the safety of microwave ablation has become a very critical issue. Summary of the Invention

[0004] In view of the shortcomings of the existing methods, the present application proposes a microwave ablation system and a control method thereof to solve the technical problem of low safety during the microwave ablation process existing in the related technologies.

[0005] In a first aspect, an embodiment of the present application provides a microwave ablation system, comprising: Liquid injection mechanism; An acquisition unit, used for acquiring a standing wave ratio parameter of the microwave ablation system during the microwave ablation process; a processing unit, electrically connected to the acquisition sensor and the adjustment control unit, and configured to send the parameter adjustment control signal to the adjustment control unit when the standing wave ratio parameter acquired by the acquisition unit exceeds a first set threshold range; An adjustment control unit is electrically connected to the acquisition unit, the processing unit and the injection mechanism, and is used to start a closed-loop control program after receiving the parameter adjustment control signal, and adjust the flow rate of the fluid medium delivered to the target tissue by the injection mechanism during microwave ablation according to the standing wave ratio parameter collected by the acquisition unit, so that the standing wave ratio parameter falls within a second set threshold range; the first set threshold range is greater than the second set threshold range.

[0006] In one possible implementation, the microwave ablation system further includes: The microwave source generator is electrically connected to the processing unit and is used to output microwave energy to the target tissue at a constant power according to the ablation signal sent by the processing unit.

[0007] In one possible implementation, the microwave ablation system further includes: The ablation needle comprises a conductive structure electrically connected with the microwave source generator and a water injection structure connected with the liquid injection mechanism through a pipeline, the conductive structure is used for outputting microwave energy to the target tissue, and the water injection structure is used for injecting the fluid medium delivered by the liquid injection mechanism into the target tissue.

[0008] In a possible implementation, the microwave ablation system further comprises: The input unit is electrically connected with the processing unit, used for inputting a first set threshold range of the standing wave ratio parameter and transmitting the first set threshold range to the processing unit.

[0009] In a possible implementation, the liquid injection mechanism comprises at least one of a peristaltic pump or a perfusion pump. The adjustment control unit is electrically connected with the control end of at least one of the peristaltic pump or the perfusion pump, used for adjusting the rotating speed of at least one of the peristaltic pump or the perfusion pump to adjust the flow of the fluid medium.

[0010] In a second aspect, the embodiments of the present application provide a control method of a microwave ablation system, applied to the microwave ablation system as described above, comprising: The acquisition unit acquires the standing wave ratio parameter of the microwave ablation system in the microwave ablation process. The processing unit determines whether the standing wave ratio parameter exceeds a first set threshold range. The adjustment control unit starts a closed-loop control program when the standing wave ratio parameter exceeds the first set threshold range, adjusts the flow of the fluid medium delivered by the liquid injection mechanism to the target tissue in the microwave ablation process according to the standing wave ratio parameter, so that the standing wave ratio parameter falls within a second set threshold range; and the first set threshold range is greater than the second set threshold range.

[0011] In a possible implementation, the adjusting the flow of the fluid medium delivered to the target tissue according to the standing wave ratio parameter so that the standing wave ratio parameter falls within the second set threshold range, and the first set threshold range being greater than the second set threshold range, comprises: The adjustment control unit starts a closed-loop control program when the standing wave ratio parameter exceeds the first set threshold range, judges whether the standing wave ratio parameter is greater than a set threshold value; and the set threshold value is within the second set threshold range. When the standing wave ratio parameter is greater than the set threshold value, the flow of the fluid medium delivered by the liquid injection mechanism to the target tissue is increased. When the standing wave ratio parameter is less than or equal to the set threshold value, the flow of the fluid medium delivered by the liquid injection mechanism to the target tissue is decreased.

[0012] In a possible implementation, before the acquisition unit acquires the standing wave ratio parameter of the microwave ablation system during the microwave ablation process, the method further includes: The microwave source generator outputs microwave energy at a constant power to the target tissue.

[0013] In a possible implementation, the lower limit of the first set threshold range is in a range of 1.0 to 1.3, and the upper limit of the first set threshold range is in a range of 1.35 to 1.65.

[0014] In one possible implementation, when the standing wave ratio parameter exceeds a first set threshold range, the regulating and controlling unit adjusts the flow rate of the fluid medium delivered to the target tissue according to the standing wave ratio parameter so that the standing wave ratio parameter falls within a second set threshold range; after the first set threshold range exceeds the second set threshold range, the regulating and controlling unit further includes: The processing unit triggers an early warning when the flow rate of the fluid medium delivered to the target tissue exceeds a preset flow rate, wherein the preset flow rate ranges from 2 to 10 milliliters per minute.

[0015] The beneficial technical effects brought about by the technical solutions provided in the embodiments of the present application include: The acquisition unit acquires the standing wave ratio (SWR) parameter of the microwave ablation system during microwave ablation, thereby achieving safety monitoring during the microwave ablation process. The processing unit sends a parameter adjustment control signal to the adjustment control unit when the SWR parameter acquired by the acquisition unit exceeds a first set threshold range, thereby triggering the adjustment control unit to perform closed-loop adjustment of the SWR. The closed-loop control algorithm embedded in the adjustment control unit adjusts the flow rate of the fluid medium delivered to the target tissue by the injection mechanism, thereby achieving closed-loop adjustment of the SWR, so that the SWR parameter fluctuates around the set threshold (i.e., the SWR parameter falls within a second set threshold range). In this way, while ensuring that the microwave ablation output power does not decrease, the SWR parameter is maintained relatively stable, the target tissue is continuously ablated, the target tissue ablation time is shortened, and the problem of excessive reflected power due to an excessively large SWR parameter is avoided, thereby ensuring that the probability of the ablation needle being disconnected or broken is very low, and the service life of the microwave source generator is also increased. In addition, due to the continuous low impedance state of the target tissue and the continuous injection of the fluid medium, the temperature of the target tissue can be kept low, thereby ensuring that the target tissue is not carbonized or the degree of carbonization is very low.

[0016] Additional aspects and advantages of the present application will be given in part in the following description, which will become apparent from the following description, or will be learned through practice of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The above and / or additional aspects and advantages of the present application will become apparent and easily understood from the following description of the embodiments in conjunction with the accompanying drawings, in which: Figure 1 A schematic diagram of a microwave ablation system framework provided by an embodiment of the present application is shown in FIG. 1. Figure 2 A flowchart of a control method of a microwave ablation system provided by an embodiment of the present application is shown in FIG. 2. Figure 3 A flowchart of another control method of a microwave ablation system provided by an embodiment of the present application is shown in FIG. 3. Figure 4 A curve graph of a standing wave ratio changing with a load in the related art is shown in FIG. 4. Figure 5 A graph of the relationship between a standing wave ratio and a load after a microwave ablation system provided by an embodiment of the present application works is shown in FIG. 5. Explanation of reference signs: 10-target tissue; 11-liquid injection mechanism; 12-acquisition unit; 13-processing unit; 14-regulation and control unit; 15-microwave source generator; 16-ablation needle; 17-input unit.

[0018] It should be noted that the dashed line and the solid line in the drawing of the present application for connecting components represent the liquid circuit and the electric circuit, respectively. DETAILED DESCRIPTION

[0019] The embodiments of the present application will be described below in conjunction with the accompanying drawings of the present application. It should be understood that the embodiments described below in conjunction with the accompanying drawings are exemplary descriptions of the technical solutions of the embodiments of the present application, and do not constitute a limitation on the technical solutions of the embodiments of the present application.

[0020] Those skilled in the art can understand that, unless specifically stated otherwise, "the" and "that" used herein can also include plural forms. It should be further understood that the phrase "comprising" used in the specification of the present application means that the steps, operations, elements and / or components exist, but does not exclude other features, information, data, steps, operations, elements, components and / or combinations thereof supported by the present art. It should be understood that when we say that an element is "connected" or "coupled" to another element, the element can be directly connected or coupled to the other element, or can mean that the element and the other element are connected through an intermediate element. In addition, "connected" or "coupled" used herein can include wireless connection or wireless coupling. The term "and / or" used herein means at least one of the items defined by the term, for example, "A and / or B" can be implemented as "A", or as "B", or as "A and B".

[0021] In order to make the purpose, technical solutions and advantages of the present application clearer, the embodiments of the present application will be described in further detail below in conjunction with the accompanying drawings.

[0022] Cancer is a common, age-old disease that poses a serious threat to human health. Developing effective tumor treatments has long been a goal of clinical medicine. With the rapid development of tumor hyperthermia technology, microwave ablation, with its minimally invasive, effective, simple, and relatively low-cost advantages, has gained widespread application and has become a leading hyperthermia treatment option.

[0023] During microwave ablation, the microwave reflection properties of the target tissue can change, potentially leading to a sudden increase in reflected power. Magnetrons are commonly used as microwave generators in related technologies. Sudden changes in reflected power can cause the magnetron to hop, affecting its proper operation. The reflected power can even heat the magnetron, burning out the cathode filament and rendering it useless. Furthermore, excessive reflected power can cause the microwave ablation needle to break.

[0024] To protect the microwave generator and microwave ablation needles and improve safety, related technologies typically monitor microwave reflected power and adjust the microwave source's transmission power accordingly. However, due to the complex variations in the microwave reflection characteristics of target tissue, if the monitoring threshold is set too high, there is still a risk of damage to the microwave generator and microwave ablation needles; if the monitoring threshold is set too low, the ablation effect of the target tissue may be affected.

[0025] The following is a detailed description of the technical solution of the present application and how the technical solution of the present application solves the above-mentioned technical problems with specific embodiments. It should be noted that the following embodiments can refer to, draw on, or combine with each other, and the same terms, similar features, and similar implementation steps in different embodiments will not be repeated.

[0026] The present invention provides a microwave ablation system. Figure 1 , including a liquid injection mechanism 11, a collection unit 12, a processing unit 13 and an adjustment and control unit 14.

[0027] The injection mechanism 11 is used to control the flow rate of the fluid medium delivered to the target tissue 10 during the microwave ablation process.

[0028] The acquisition unit 12 is used to acquire the standing wave ratio parameters of the microwave ablation system during the microwave ablation process.

[0029] The processing unit 13 is electrically connected to the acquisition sensor and the adjustment control unit 14 , and is configured to send a parameter adjustment control signal to the adjustment control unit 14 when the standing wave ratio parameter acquired by the acquisition unit 12 exceeds a first set threshold range.

[0030] The adjustment control unit 14 is electrically connected to the acquisition unit 12, the processing unit 13 and the injection mechanism 11, and is used to start a closed-loop control program after receiving the parameter adjustment control signal, and adjust the flow rate of the fluid medium delivered to the target tissue 10 by the injection mechanism 11 during the microwave ablation process according to the standing wave ratio parameter collected by the acquisition unit 12, so that the standing wave ratio parameter falls within the second set threshold range; the first set threshold range is greater than the second set threshold range.

[0031] The standing wave ratio (SWR) is an important metric for measuring the impedance matching between the power source and the load in radio frequency transmission systems (such as microwave ablation systems), significantly impacting power transmission effectiveness. Specifically, it describes the ratio of the maximum to minimum values ​​in the voltage or current waveform propagating along the transmission line. Ideally, when the transmission line perfectly matches its load (i.e., there are no reflected waves), the SWR is 1:1, indicating optimal matching. However, in practical applications, imperfect matching due to various factors can generate reflected waves, thus forming standing waves, resulting in a SWR greater than 1.

[0032] The closer the SWR is to 1, the better the impedance matching between the transmission line and the load, the smaller the reflected power, and the higher the microwave energy transmission efficiency; a high SWR means more power reflection and power loss, and higher reflected power will cause the risk of damage to the microwave generator and the microwave ablation needle 16.

[0033] In this embodiment, the target tissue 10 is the load.

[0034] In this embodiment, the parameter adjustment control signal is used to start the closed-loop control program embedded in the adjustment control unit 14; after the closed-loop control program is started, the adjustment control unit 14 adjusts the flow rate of the fluid medium delivered to the target tissue 10 by the injection mechanism 11 during the microwave ablation process based on the real-time standing wave ratio parameters collected by the acquisition unit 12 and the embedded closed-loop control algorithm.

[0035] The standing wave ratio parameter of the microwave ablation system during the microwave ablation process is collected by the collection unit 12 to realize safety monitoring during the microwave ablation process; when the standing wave ratio parameter collected by the collection unit 12 exceeds the first set threshold range, the processing unit 13 sends a parameter adjustment control signal to the adjustment control unit 14 to trigger the adjustment control unit 14 to perform closed-loop adjustment of the standing wave ratio; the closed-loop control algorithm embedded in the adjustment control unit 14 adjusts the flow of fluid medium delivered by the liquid injection mechanism 11 to the target tissue to realize closed-loop adjustment of the standing wave ratio, so that the standing wave ratio parameter fluctuates around the set threshold value (i.e. the standing wave ratio parameter falls within the second set threshold range), thereby maintaining the standing wave ratio parameter relatively stable under the premise that the microwave ablation output power can not be reduced, continuously ablates the target tissue, shortens the target tissue ablation time, and can avoid the problem of excessive reflected power caused by excessive standing wave ratio parameter, thereby ensuring that the ablation needle 16 is not broken or has a very low probability of breaking, and can also improve the service life of the microwave source generator 15.

[0036] Moreover, due to the continuous low impedance state of the target tissue 10 and the continuous injection of fluid medium, the temperature of the target tissue 10 can be kept low (e.g. not exceeding 100°C), thereby ensuring that the target tissue 10 is not carbonized or has a very low degree of carbonization.

[0037] The fluid medium can be distilled water, physiological saline, etc.

[0038] It should be noted that the first set threshold range is greater than the second set threshold range, which means that the lower limit value of the second set threshold range is greater than the lower limit value of the first set threshold range, and the upper limit value of the second set threshold range is less than the upper limit value of the first set threshold range.

[0039] In some embodiments, the lower limit value of the first set threshold range ranges from 1.0 to 1.3. For example, 1.0, 1.15, 1.2, 1.3. The upper limit value of the first set threshold range ranges from 1.35 to 1.65. For example, 1.35, 1.45, 1.5, 1.55, 1.65.

[0040] In this embodiment, the first set threshold range can be greater than or equal to 1.15 and less than or equal to 1.5. The second set threshold range can be around 1.2.

[0041] That is, when the standing wave ratio parameter exceeds 1.15 to 1.5, the adjustment control unit is started for closed-loop adjustment; the set threshold value (ideal standing wave ratio parameter) in the closed-loop adjustment program is set to 1.2, so that the standing wave ratio parameter after closed-loop adjustment fluctuates around 1.2 (i.e. falls within the second set threshold range). When the standing wave ratio parameter does not exceed 1.15 to 1.5, the adjustment control unit is not started. In this way, the standing wave ratio parameter of the microwave ablation system is maintained between 1.15 and 1.5.

[0042] In some embodiments, the adjustment control unit 14 initiates a closed-loop control program to determine whether the standing wave ratio parameter is greater than a set threshold value; the set threshold value is within a second set threshold value range.

[0043] In fact, the set threshold value can be set as the ideal standing wave ratio parameter value. The standing wave ratio parameter after closed-loop adjustment fluctuates around the set threshold value, i.e., the standing wave ratio parameter falls within the second set threshold value range.

[0044] When the standing wave ratio parameter is greater than the set threshold value, the flow of the fluid medium delivered by the liquid injection mechanism to the target tissue is increased; when the standing wave ratio parameter is less than or equal to the set threshold value, the flow of the fluid medium delivered by the liquid injection mechanism to the target tissue is decreased.

[0045] That is, when the adjustment control unit 14 executes the closed-loop control program, the adjustment control unit 14 receives the standing wave ratio parameter of the microwave ablation system in the microwave ablation process collected by the collection unit 12 in real time or at a preset time interval; compares the updated standing wave ratio parameter each time with the set threshold value (generally set as the ideal standing wave ratio parameter, and the set threshold value is within the first set threshold value range); when the updated standing wave ratio parameter is greater than the set threshold value, the flow of the fluid medium delivered by the liquid injection mechanism 11 to the target tissue 10 is increased; when the updated standing wave ratio parameter is less than the set threshold value, the flow of the fluid medium delivered by the liquid injection mechanism 11 to the target tissue 10 is decreased. By adjusting the flow of the fluid medium delivered by the liquid injection mechanism 11 to the target tissue 10, the standing wave ratio parameter of the microwave ablation system in the microwave ablation process is adjusted, so that the adjusted standing wave ratio parameter fluctuates around the set threshold value (i.e., falls within the second set threshold value range), and the closed-loop control of the standing wave ratio parameter is completed.

[0046] Referring to Figure 1 In some embodiments, the microwave ablation system can further include an input unit 17 electrically connected to the processing unit 13, and the input unit 17 is configured to input the first set threshold value range of the standing wave ratio parameter and transmit the first set threshold value range to the processing unit 13.

[0047] That is, the processing unit 13 receives the first set threshold value range of the standing wave ratio parameter input by the input unit 17 (such as a touch screen), and completes the parameter setting.

[0048] In other possible embodiments, the microwave ablation system can further include a wireless communication module, and the processing unit 13 can also accept remote commands via the wireless communication module to complete the parameter setting. That is, the processing unit 13 can also receive the first set threshold value range of the standing wave ratio parameter transmitted by an external device via the wireless communication module.

[0049] The first set threshold range can be set according to the patient's age, gender and physical indicators.

[0050] See also Figure 1 In some embodiments, the microwave ablation system may further include: a microwave source generator 15 electrically connected to the processing unit 13 , for outputting microwave energy to the target tissue 10 at a constant power according to the ablation signal sent by the processing unit 13 .

[0051] Since the microwave source generator 15 outputs microwave energy to the target tissue 10 at a constant power, it can ensure that the target tissue 10 is continuously injected with ideal and expected microwave energy, thereby ensuring that the target tissue 10 is completely ablated and saving operation time.

[0052] In some embodiments, the processing unit 13 is further configured to, upon receiving the power-on signal, send an ablation signal to the microwave source generator 15. The microwave source generator 15 continuously outputs microwave energy at a constant power to the target tissue 10 according to the ablation signal.

[0053] In some embodiments, the adjustment control unit 14 can be configured to receive the SWR parameters collected by the acquisition unit 12, execute algorithms such as PID (Proportional-Integral-Derivative) and fuzzy control, calculate the deviation between the current SWR and the preset SWR, output a corrected flow rate of the fluid medium delivered by the injection mechanism 11 to the target tissue 10, and convert this flow rate into a speed control signal for the drive motor of the injection mechanism 11. Optionally, the adjustment control unit 14 can also be configured to report real-time data (e.g., current flow rate, motor speed) to the processing unit 13 for display or recording.

[0054] In this embodiment, the processing unit 13 (central processing unit, CPU) does not directly participate in real-time PID control, but is instead responsible for global management, task scheduling, and complex computations. The regulation control unit 14 focuses on real-time closed-loop control, directly interfacing with the acquisition unit 12 and the injection mechanism 11 to ensure the accuracy and stability of the system's dynamic response. Leveraging local closed-loop feedback, it can independently perform millisecond-level adjustments without waiting for CPU intervention. This layered (distributed) architecture ensures both system flexibility (the CPU can flexibly adjust policies) and real-time and reliable control (the regulation control unit 14 focuses on execution).

[0055] In some embodiments, the acquisition unit 12 may be a standing wave ratio (SWR) acquisition sensor, also known as a standing wave ratio (SWR) meter. An SWR meter is an instrument specifically designed to measure the voltage standing wave ratio (VSWR) on a transmission line. It is typically installed in the RF signal path and can directly read the SWR value.

[0056] The operating steps for detecting the SWR value using an SWR meter are as follows: connect the microwave source generator 15 to one end of the SWR meter and the other end to the load (i.e., the target tissue 10); turn on the microwave source generator 15; observe the reading on the SWR meter to obtain the standing wave ratio under the current conditions.

[0057] See also Figure 1 In some embodiments, the microwave ablation system may further include: an ablation needle 16, including a conductive structure electrically connected to the microwave source generator 15, and a water injection structure connected to the injection mechanism 11 through a pipeline, the conductive structure being used to output microwave energy to the target tissue 10, and the water injection structure being used to inject the fluid medium delivered by the injection mechanism 11 into the target tissue 10.

[0058] Figure 1 The dotted lines and solid lines used to connect components represent the fluid path and the electrical path, respectively. Figure 1 The middle liquid injection mechanism 11 is connected to the ablation needle 16 through a liquid path, and the liquid outlet of the liquid injection mechanism 11 is connected to the liquid inlet of the water injection structure of the ablation needle 16 .

[0059] The ablation needle 16 can be used to output microwave energy to the target tissue 10 and inject the fluid medium delivered by the injection mechanism 11 into the target tissue 10, thereby eliminating the need to pierce two structures into the target tissue 10. This makes the operation simpler, reduces damage to the patient, and improves the safety of microwave ablation.

[0060] In some embodiments, the injection mechanism 11 may include at least one of a peristaltic pump or an infusion pump; the adjustment control unit 14 is electrically connected to the control end of at least one of the peristaltic pump or the infusion pump, and is used to adjust the rotational speed of at least one of the peristaltic pump or the infusion pump to adjust the flow rate of the fluid medium.

[0061] In some embodiments, the driving circuit in the adjustment control unit 14 is electrically connected to the motor of at least one of the peristaltic pump or the perfusion pump, and the flow rate of the fluid medium is adjusted by adjusting the speed of the driving motor of at least one of the peristaltic pump or the perfusion pump.

[0062] Peristaltic pumps consist of a drive motor and an elastic hose. The drive motor periodically squeezes the hose to achieve unidirectional fluid flow, thereby delivering the fluid medium. The drive motor can include a stepper motor (high precision), a brushless DC motor (wide speed range), or a servo motor (closed-loop control). Perfusion pumps can include a stepper motor and a lead screw drive, converting the stepper motor's rotational motion into precise linear propulsion, pushing the syringe piston and delivering the fluid medium.

[0063] The beneficial technical effects brought about by the technical solutions provided in the embodiments of the present application include: The acquisition unit 12 is used to acquire the standing wave ratio parameters of the microwave ablation system during the microwave ablation process, thereby realizing safety monitoring during the microwave ablation process; the processing unit 13 is used to send a parameter adjustment control signal to the adjustment control unit 14 when the standing wave ratio parameter acquired by the acquisition unit 12 exceeds the first set threshold range, thereby triggering the adjustment control unit 14 to perform closed-loop adjustment of the standing wave ratio; the closed-loop control algorithm embedded in the adjustment control unit 14 is used to adjust the flow rate of the fluid medium delivered to the target tissue by the injection mechanism 11, thereby realizing closed-loop adjustment of the standing wave ratio, so that the standing wave ratio parameter fluctuates around the set threshold (that is, the standing wave ratio parameter falls within the second set threshold range), thereby maintaining the standing wave ratio parameter relatively stable while ensuring that the microwave ablation output power does not decrease, continuously ablating the target tissue, shortening the target tissue ablation time, and avoiding the problem of excessive reflected power caused by excessive standing wave ratio parameters, thereby ensuring that the probability of the ablation needle 16 being disconnected or broken is very low, and also improving the service life of the microwave source generator 15.

[0064] Furthermore, since the target tissue 10 is in a continuous low impedance state and the fluid medium is continuously injected, the temperature of the target tissue 10 can be kept low, thereby ensuring that the target tissue 10 is not carbonized or the degree of carbonization is very low.

[0065] Based on the same inventive concept, the present invention provides a control method for a microwave ablation system, which is applied to the microwave ablation system as described above. Figure 2 The control method of the microwave ablation system includes steps S11 to S13.

[0066] S11: The acquisition unit 12 acquires the standing wave ratio parameters of the microwave ablation system during the microwave ablation process.

[0067] S12: The processing unit 13 determines whether the standing wave ratio parameter exceeds a first set threshold range.

[0068] S13: When the standing wave ratio parameter exceeds the first set threshold range, the adjustment control unit 14 starts the closed-loop control program and adjusts the flow rate of the fluid medium delivered to the target tissue 10 according to the standing wave ratio parameter so that the standing wave ratio parameter falls within the second set threshold range; the first set threshold range is greater than the second set threshold range.

[0069] The acquisition unit 12 is used to acquire the standing wave ratio parameters of the microwave ablation system during the microwave ablation process, thereby realizing safety monitoring during the microwave ablation process; the processing unit 13 is used to send a parameter adjustment control signal to the adjustment control unit 14 when the standing wave ratio parameter acquired by the acquisition unit 12 exceeds the first set threshold range, thereby triggering the adjustment control unit 14 to perform closed-loop adjustment of the standing wave ratio; the closed-loop control algorithm embedded in the adjustment control unit 14 is used to adjust the flow rate of the fluid medium delivered to the target tissue by the injection mechanism 11, thereby realizing closed-loop adjustment of the standing wave ratio, so that the standing wave ratio parameter fluctuates around the set threshold (that is, the standing wave ratio parameter falls within the second set threshold range), thereby maintaining the standing wave ratio parameter relatively stable while ensuring that the microwave ablation output power does not decrease, continuously ablating the target tissue, shortening the target tissue ablation time, and avoiding the problem of excessive reflected power caused by excessive standing wave ratio parameters, thereby ensuring that the probability of the ablation needle 16 being disconnected or broken is very low, and also improving the service life of the microwave source generator 15.

[0070] Furthermore, since the target tissue 10 is in a continuous low impedance state and the fluid medium is continuously injected, the temperature of the target tissue 10 can be kept low, thereby ensuring that the target tissue 10 is not carbonized or the degree of carbonization is very low.

[0071] In some embodiments, the acquisition unit 12 can acquire the standing wave ratio parameters of the microwave ablation system in real time during the microwave ablation process. Correspondingly, the adjustment control unit 14 adjusts the flow rate of the fluid medium delivered by the injection mechanism 11 to the target tissue 10 during the microwave ablation process based on the real-time standing wave ratio parameters.

[0072] In other feasible embodiments, the acquisition unit 12 may acquire a standing wave ratio parameter of the microwave ablation system during the microwave ablation process at a second preset time interval. Correspondingly, the adjustment control unit 14 may adjust the flow rate of the fluid medium delivered by the injection mechanism 11 to the target tissue 10 during the microwave ablation process based on the current standing wave ratio parameter at a second preset time interval.

[0073] In some embodiments, the lower limit of the first set threshold range is in the range of 1.0 to 1.3, for example, 1.0, 1.15, 1.2, or 1.3.

[0074] The upper limit value of the first set threshold range is in the range of 1.35 to 1.65, for example, 1.35, 1.45, 1.5, 1.55, and 1.65.

[0075] For example, the first set threshold value may be greater than or equal to 1.15 and less than or equal to 1.5. This setting allows the standing wave ratio of the microwave ablation system to always be maintained within an ideal and safe range.

[0076] In some embodiments, step S13 may include: when the standing wave ratio parameter exceeds a first set threshold range, the regulating control unit starts a closed-loop control program to determine whether the standing wave ratio parameter is greater than the set threshold; setting the threshold within a second set threshold range; when the standing wave ratio parameter is greater than the set threshold, increasing the flow rate of the fluid medium delivered by the injection mechanism to the target tissue; when the standing wave ratio parameter is less than or equal to the set threshold, reducing the flow rate of the fluid medium delivered by the injection mechanism to the target tissue.

[0077] In some embodiments, the regulation control unit may have an embedded closed-loop control algorithm. The closed-loop control algorithm may be proportional control, PID (Proportional-Integral-Derivative) control, fuzzy control, or other algorithms. The closed-loop control program includes a computer-executable instruction sequence based on the closed-loop control algorithm.

[0078] In this embodiment, the closed-loop control algorithm can be proportional control. Specifically, the flow rate of the fluid medium delivered to the target tissue 10 can be proportional to the difference between the standing wave ratio parameter and a preset threshold. That is, y = k(xa), where y represents the flow rate of the fluid medium delivered to the target tissue 10, x represents the standing wave ratio parameter of the microwave ablation system during the microwave ablation process collected by the acquisition unit 12, a represents the preset threshold, and k is a constant and positive number. The preset threshold can be 1.15, 1.2, etc.

[0079] In some embodiments, before step S11 , the following may be included: the microwave source generator 15 outputs microwave energy to the target tissue 10 at a constant power.

[0080] Specifically, the microwave source generator 15 can output microwave energy at a constant power to the target tissue 10 based on the ablation signal sent by the processing unit 13. In some embodiments, after receiving a power-on signal, the processing unit 13 sends an ablation signal to the microwave source generator 15. The microwave source generator 15 continuously outputs microwave energy at a constant power to the target tissue 10 based on the ablation signal.

[0081] By adjusting the control unit 14 for closed-loop control, the microwave source generator 15 outputs microwave energy to the target tissue 10 at a constant power, thereby not only ensuring that the ablation needle 16 does not break or has a very low probability of breaking, thereby improving the service life of the microwave source generator 15, and ensuring that the target tissue 10 is not carbonized or has a very low degree of carbonization, but also ensuring that the target tissue 10 is continuously injected with ideal and expected microwave energy, thereby ensuring that the target tissue 10 is completely ablated and saving surgical time.

[0082] In some embodiments, before the microwave source generator 15 outputs microwave energy to the target tissue 10 at a constant power, the input unit 17 can further input a first set threshold range of the standing wave ratio parameter.

[0083] For example, the embodiments of the present application provide another method for controlling a microwave ablation system, which comprises steps S11-S13. Figure 3

[0084] S21: The input unit 17 inputs a first set threshold range of the standing wave ratio parameter.

[0085] S22: The microwave source generator 15 outputs microwave energy to the target tissue 10 at a constant power.

[0086] S23: The acquisition unit 12 acquires the standing wave ratio parameter of the microwave ablation system during the microwave ablation process.

[0087] S24: The processing unit 13 determines whether the standing wave ratio parameter exceeds the first set threshold range. If yes, step S25 is performed; if no, step S23 is returned.

[0088] S25: The adjustment control unit 14 starts a closed-loop control program to adjust the flow rate of the fluid medium delivered to the target tissue 10 according to the standing wave ratio parameter, so that the standing wave ratio parameter falls within a second set threshold range; the first set threshold range is greater than the second set threshold range.

[0089] In some embodiments, after step S25, the processing unit 13 can further trigger a warning when the flow rate of the fluid medium delivered to the target tissue 10 exceeds a preset flow rate, wherein the preset flow rate ranges from 2 to 10 milliliters per minute.

[0090] That is, the preset flow rate is greater than or equal to 2 milliliters per minute, and the preset flow rate is less than or equal to 10 milliliters per minute. For example, the preset flow rate is 2 milliliters per minute, 4 milliliters per minute, 6 milliliters per minute, 8 milliliters per minute, or 10 milliliters per minute.

[0091] In this way, the problem of excessive flow rate causing greater side effects to the patient can be avoided, for example, the problem of normal cells being unable to absorb water due to excessive flow rate, causing local tissue edema and inflammation.

[0092] In some embodiments, when the flow rate of the fluid medium delivered to the target tissue 10 exceeds the preset flow rate, the processing unit 13 can send a warning message to the display screen, and the display screen displays the warning message, wherein the warning message can be a warning text, a warning picture, or a warning video.

[0093] ​In other feasible embodiments, the processing unit 13 may send a warning message to an alarm when the flow rate of the fluid medium delivered to the target tissue 10 exceeds a preset flow rate, and the alarm emits an alarm sound after receiving the alarm message.

[0094] The following describes a control method for a microwave ablation system by taking an example. The control method for a microwave ablation system includes the following steps: S0: The microwave ablation system starts, for example, the system is powered on. S1. Setting a first threshold range of a standing wave ratio parameter in a microwave ablation system (for example, the threshold range may be 1.15 to 1.5). For example, a user inputs the threshold range of the standing wave ratio parameter through a touch screen.

[0095] S2. Start the microwave source generator 15 to output microwave energy to the target tissue 10 at a constant power.

[0096] S3. The acquisition unit 12 (eg, a standing wave ratio acquisition sensor) acquires the standing wave ratio (ie, standing wave ratio parameter) of the microwave ablation system during the microwave ablation process.

[0097] like Figure 4 As shown, Figure 4 As the power output of the microwave source generator 15 continues, the water in the human lesion tissue evaporates faster and faster, the load impedance of the human lesion tissue continues to increase, and the standing wave ratio increases with the increase of load. S4, the processing unit 13 determines whether to adjust and control the standing wave ratio based on the standing wave ratio collected in step S3 by comparing the standing wave ratio collected in step S3 with the set threshold range set in step S1 (for example, the first set threshold range can be 1.15 to 1.5); when the standing wave ratio is not within the set threshold range, the standing wave ratio needs to be adjusted and controlled, and a control signal (i.e., a parameter adjustment control signal) is sent to the adjustment control unit 14.

[0098] S5. Perform PID (Proportional-Integral-Derivative) control according to the control signal of S4, and transmit the adjustment parameters to the injection mechanism 11 (for example, a peristaltic pump or an infusion pump, where the speed of the peristaltic pump or the infusion pump is 0-300 rpm and the corresponding flow rate is 0-110 ml / min).

[0099] S6. The liquid injection mechanism 11 (eg, a peristaltic pump or an infusion pump) operates to control the standing wave ratio to remain within a constant set threshold range (eg, the second set threshold range may be around 1.2) under different loads. Figure 5 shown.

[0100] S7. Continue to collect the standing wave ratio parameters of the microwave ablation system during the microwave ablation process.

[0101] S8. Repeat steps S5, S6, and S7 to enter the loop.

[0102] S9, end. That is, turn off the microwave source generator 15 and close the liquid injection mechanism 11.

[0103] The control method of the microwave ablation system of this embodiment corresponds to the aforementioned microwave ablation system, has similar implementation principles, and can achieve similar technical effects, which will not be described in detail here.

[0104] Those skilled in the art will appreciate that the steps, measures, and schemes in the various operations, methods, and processes discussed in this application may be interchanged, modified, combined, or deleted. Furthermore, other steps, measures, and schemes in the various operations, methods, and processes discussed in this application may also be interchanged, modified, rearranged, decomposed, combined, or deleted. Furthermore, steps, measures, and schemes in the related art that are similar to those disclosed in this application may also be interchanged, modified, rearranged, decomposed, combined, or deleted.

[0105] The terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of the technical features being referred to. Thus, a feature specified as "first" or "second" may explicitly or implicitly include one or more of such features. Throughout this application, unless otherwise specified, "plurality" means two or more.

[0106] The above is only part of the implementation methods of the present application. It should be pointed out that for ordinary technicians in this technical field, without departing from the technical concept of the solution of the present application, other similar implementation methods based on the technical ideas of the present application also fall within the protection scope of the embodiments of the present application.

Claims

1. A microwave ablation system, characterized in that: include: Liquid injection mechanism; An acquisition unit, used for acquiring a standing wave ratio parameter of the microwave ablation system during the microwave ablation process; a processing unit, electrically connected to the acquisition sensor and the adjustment control unit, and configured to send the parameter adjustment control signal to the adjustment control unit when the standing wave ratio parameter acquired by the acquisition unit exceeds a first set threshold range; An adjustment control unit is electrically connected to the acquisition unit, the processing unit and the injection mechanism, and is used to start a closed-loop control program after receiving the parameter adjustment control signal, and adjust the flow rate of the fluid medium delivered to the target tissue by the injection mechanism during microwave ablation according to the standing wave ratio parameter collected by the acquisition unit, so that the standing wave ratio parameter falls within a second set threshold range; the first set threshold range is greater than the second set threshold range.

2. The microwave ablation system according to claim 1, characterized in that: Also includes: The microwave source generator is electrically connected to the processing unit and is used to output microwave energy to the target tissue at a constant power according to the ablation signal sent by the processing unit.

3. The microwave ablation system according to claim 2, characterized in that: Also includes: The ablation needle includes a conductive structure electrically connected to the microwave source generator and a water injection structure connected to the injection mechanism through a pipeline. The conductive structure is used to output microwave energy to the target tissue, and the water injection structure is used to inject the fluid medium transported by the injection mechanism into the target tissue.

4. The microwave ablation system according to claim 1, characterized in that: Also includes: An input unit is electrically connected to the processing unit and is used to input a first set threshold range of a standing wave ratio parameter and transmit the first set threshold range to the processing unit.

5. The microwave ablation system according to claim 1, characterized in that: The injection mechanism includes at least one of a peristaltic pump or an infusion pump; The regulating control unit is electrically connected to the control end of at least one of the peristaltic pump or the perfusion pump, and is used to regulate the rotation speed of at least one of the peristaltic pump or the perfusion pump to adjust the flow rate of the fluid medium.

6. A control method for a microwave ablation system, characterized in that: A microwave ablation system according to any one of claims 1 to 5, comprising: The collecting unit collects the standing wave ratio parameters of the microwave ablation system during the microwave ablation process; The processing unit determines whether the standing wave ratio parameter exceeds a first set threshold range; When the standing wave ratio parameter exceeds a first set threshold range, the regulating control unit starts a closed-loop control program and adjusts the flow rate of the fluid medium delivered to the target tissue according to the standing wave ratio parameter so that the standing wave ratio parameter falls within a second set threshold range; the first set threshold range is greater than the second set threshold range.

7. The control method of the microwave ablation system according to claim 6, characterized in that: When the standing wave ratio parameter exceeds a first set threshold range, the regulating control unit starts a closed-loop control program to adjust the flow rate of the fluid medium delivered to the target tissue according to the standing wave ratio parameter so that the standing wave ratio parameter falls within a second set threshold range; The first set threshold range is greater than the second set threshold range, including: When the standing wave ratio parameter exceeds a first set threshold range, the regulating control unit starts a closed-loop control program to determine whether the standing wave ratio parameter is greater than a set threshold; and the set threshold is within a second set threshold range; When the standing wave ratio parameter is greater than the set threshold, increasing the flow rate of the fluid medium delivered by the injection mechanism to the target tissue; When the standing wave ratio parameter is less than or equal to the set threshold, the flow rate of the fluid medium delivered by the injection mechanism to the target tissue is reduced.

8. The control method of the microwave ablation system according to claim 6, characterized in that: Before the acquisition unit acquires the standing wave ratio parameter of the microwave ablation system during the microwave ablation process, the method further includes: The microwave source generator outputs microwave energy at a constant power to the target tissue.

9. The control method of the microwave ablation system according to any one of claims 6 to 8, characterized in that: The lower limit value of the first set threshold range is in the range of 1.0 to 1.3, and the upper limit value of the first set threshold range is in the range of 1.35 to 1.

65.

10. The control method of the microwave ablation system according to claim 6, characterized in that: When the standing wave ratio parameter exceeds the first set threshold range, the regulating control unit adjusts the flow rate of the fluid medium delivered to the target tissue according to the standing wave ratio parameter so that the standing wave ratio parameter falls within the second set threshold range; After the first set threshold range is greater than the second set threshold range, the method further includes: The processing unit triggers an early warning when the flow rate of the fluid medium delivered to the target tissue exceeds a preset flow rate, wherein the preset flow rate ranges from 2 to 10 milliliters per minute.

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