A composition for promoting proliferation of mesenchymal stem cells and / or relieving damage to spermatogonia, and a preparation method and application thereof

By using scientifically formulated traditional Chinese medicine combinations, ultra-micro pulverization technology, and pharmaceutical excipients to prepare traditional Chinese medicine preparations, the problem of lack of synergistic effects in existing traditional Chinese medicine combinations has been solved, achieving mesenchymal stem cell proliferation and spermatogonial cell damage repair, thus improving reproductive health.

CN120789213BActive Publication Date: 2026-06-19HUNAN YUANPIN CELL TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HUNAN YUANPIN CELL TECH CO LTD
Filing Date
2025-07-22
Publication Date
2026-06-19

AI Technical Summary

Technical Problem

Existing Chinese medicine formulations lack synergistic effects on stem cell proliferation, anti-oxidation, and anti-aging, and cannot effectively alleviate spermatogonial cell damage and reproductive aging problems caused by chemotherapy or radiation.

Method used

A combination of traditional Chinese medicines, including ginseng, maca, oyster peptides, and sika deer antler, is prepared into tablets, capsules, and other dosage forms through ultra-micro pulverization and mixing with pharmaceutical excipients. This promotes the proliferation of mesenchymal stem cells and repairs damage to spermatogonia.

Benefits of technology

It significantly promotes the proliferation of mesenchymal stem cells, repairs spermatogonial damage caused by oxidative stress and aging, improves spermatogenic dysfunction, reduces ROS levels, and delays reproductive and systemic aging.

✦ Generated by Eureka AI based on patent content.

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Abstract

This invention provides a composition for promoting mesenchymal stem cell proliferation and / or alleviating spermatogonial cell damage, its preparation method, and its application, belonging to the technical field of traditional Chinese medicine compositions. A composition is prepared from the following raw materials in parts by weight: 10-20 parts ginseng, 5-15 parts maca, 5-10 parts oyster peptide, 5-15 parts deer antler velvet, 3-8 parts deer blood, 3-8 parts ginger, 5-8 parts cistanche deserticola, 4-10 parts sea cucumber peptide, 4-8 parts polygonatum sibiricum, 5-10 parts burdock root, 2-5 parts wolfberry powder, and 1-3 parts eucommia ulmoides leaf. The composition is prepared into a traditional Chinese medicine preparation using an ultra-micro pulverization process. This preparation promotes the proliferation of mesenchymal stem cells (MSCs), repairs spermatogonial cell damage caused by oxidative stress (such as chemotherapy, radiation) or aging (such as age-related damage), reduces ROS levels, improves spermatogenic dysfunction, assists in the treatment of male infertility, and delays aging of the reproductive system and the whole body.
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