Medical radiation resistant nonwoven fabric and method of making same

Abstract

The application discloses a medical irradiation-resistant non-woven fabric and a preparation method thereof, and belongs to the technical field of non-woven fabrics. The medical irradiation-resistant non-woven fabric comprises the following raw materials in mass fractions: 100 mass parts of polypropylene resin, 1-2 mass parts of irradiation-resistant stabilizer, 1-2 mass parts of antibacterial agent, 0.4-0.6 mass parts of antistatic agent, 0.6-0.8 mass parts of antioxidant, 0.6-0.8 mass parts of lubricant, 0.1-0.2 mass parts of stearate, and the irradiation-resistant stabilizer is prepared by grafting an amino group on a carbonyl-containing aromatic hydrocarbon substrate through a carrier coated with an absorbent. The irradiation-resistant stabilizer is introduced in the preparation process of the polypropylene non-woven fabric, so that the irradiation-resistant performance of the non-woven fabric is improved, and the non-woven fabric still has certain anti-fracture performance and toughness after multiple irradiations.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of non-woven fabrics, and particularly relates to a medical radiation-resistant non-woven fabric and a preparation method thereof. BACKGROUND

[0002] In the current medical industry, spunbond non-woven fabric, as an important material, is widely used in the production of disposable medical operating gowns, protective clothing and other various medical protective products. However, these products usually adopt an ethylene oxide sterilization process in the production process. Although ethylene oxide sterilization can achieve the expected sterilization effect to a certain extent, it has great safety hazards in the production and processing process, such as flammability and explosion risks. In addition, ethylene oxide sterilization also causes environmental pollution problems, and may leave harmful chemical substances to the human body after sterilization, which poses a potential threat to human health. In addition, the cycle of ethylene oxide sterilization is relatively long, which not only affects the production efficiency of medical protective products, but also has adverse effects on the health of medical staff who wear and contact the medical protective products sterilized by ethylene oxide for a long time. In view of this, irradiation sterilization, as an efficient and rapid sterilization method, has attracted more and more attention.

[0003] A radiation-resistant polypropylene non-woven fabric provided by Chinese patent CN112899878B can reduce the influence of electron beam on the appearance of the material and improve the radiation resistance of the material by adding a plurality of hindered amine light stabilizers, but cannot improve the mechanical properties of the material after irradiation. The light stabilizer will lose effectiveness due to the destruction of its own structure under long-term irradiation, and has poor durability, which cannot meet the strict quality and safety requirements of the medical industry. Therefore, developing a medical non-woven fabric that can withstand irradiation sterilization treatment and has stable performance is of great significance to ensure the quality and safety of medical products. This not only improves the use efficiency of medical protective products, but also effectively protects the health and safety of medical staff. SUMMARY

[0004] The purpose of the present application is to provide a medical radiation-resistant non-woven fabric and a preparation method thereof, which can solve the problem of poor radiation resistance of non-woven fabric and significant reduction in mechanical strength of non-woven fabric after multiple irradiations.

[0005] The purpose of the present application can be achieved by the following technical solutions:

[0006] A medical radiation-resistant non-woven fabric comprises the following raw materials in mass fraction:

[0007] Polypropylene resin 100 parts by mass; radiation resistant stabilizer 1-2 parts by mass; antibacterial agent 1-2 parts by mass; antistatic agent 0.4-0.6 parts by mass; antioxidant 0.6-0.8 parts by mass; lubricant 0.6-0.8 parts by mass; stearate 0.1-0.2 parts by mass;

[0008] The radiation resistant stabilizer is prepared by grafting amino groups on a carbonyl-containing aromatic hydrocarbon substrate with a support coated with an absorbent.

[0009] As a preferred technical solution of the present application, the absorbent is selected from at least one of yttrium, barium, cerium, gadolinium, bismuth, strontium, samarium, neodymium, erbium, lutetium, ytterbium salt.

[0010] As a preferred technical solution of the present application, the absorbent is composed of cerium chloride, yttrium chloride, erbium chloride.

[0011] As a preferred technical solution of the present application, the support is selected from any one of halloysite nanotube, kaolin, diatomite, carbon nanotube, sepiolite, graphene, mesoporous silica.

[0012] As a preferred technical solution of the present application, when the support is selected as kaolin, an ordered porous structure can be manufactured in the structure of kaolin by using a biological template method to obtain a kaolin support, and then the absorbent is filled into the inner cavity of the kaolin support by a vacuum negative pressure method for loading.

[0013] As a preferred technical solution of the present application, when the support is selected as graphene, the absorbent is loaded by graphene adsorption, and then a polydopamine surface coating is obtained to obtain an amino structure.

[0014] As a preferred technical solution of the present application, the support is preferably a hydroxylated multi-walled carbon nanotube.

[0015] As a preferred technical solution of the present application, the aromatic hydrocarbon substrate is selected from at least one of benzophenone, benzoquinone, methylbenzoquinone, 2-benzoquinone, 2-phenyl-1,4-benzoquinone, naphthacene ketone, 1-benzoylisoquinoline, 4-ethylbenzophenone, 4-phenylbenzophenone, 5,12-naphthalene naphthoquinone, anthraquinone, senna, 2-methylanthraquinone, 1,4-anthraquinone, 2-phenylanthraquinone, phenanthraquinone, 1,4-curanone.

[0016] As a preferred technical solution of the present application, the aromatic hydrocarbon substrate is preferably 1,4-curanone.

[0017] As a preferred technical solution of the present application, the antibacterial agent is a guanidine antibacterial agent.

[0018] As a preferred technical solution of the present application, the antistatic agent is NW16 antistatic agent.

[0019] As a preferred technical solution of the present application, the antioxidant is selected from at least one of antioxidant 626 and antioxidant 1010.

[0020] As a preferred technical solution of the present application, the lubricant is any one of glycerol stearate and paraffin.

[0021] As a preferred technical solution of the present application, the stearate salt is at least one of magnesium stearate, zinc stearate and calcium stearate.

[0022] The preparation method of the medical irradiation-resistant non-woven fabric comprises the following steps:

[0023] S1, the raw materials of the formula amount are mixed uniformly and then put into a double-screw extruder for melt extrusion to obtain a melt; the temperature of the double-screw extruder is controlled to be 160-200 DEG C, and the screw rotation speed is controlled to be 200-300 rpm;

[0024] S2, the melt is put into a composite spinning machine, sprayed from a spinneret at a pressure of 7-9 MPa to form a yarn, and then cooled by blowing to obtain a composite fiber;

[0025] S3, the composite fiber is pressed by a hot press roller at 80 DEG C and fixed and formed under the condition of 120 DEG C and 10 MPa to obtain the medical irradiation-resistant non-woven fabric.

[0026] The present application has the following advantages:

[0027] The present application introduces an irradiation-resistant stabilizer in the preparation process of the polypropylene non-woven fabric, thereby improving the irradiation resistance of the non-woven fabric, so that the non-woven fabric still has certain anti-fracture performance and toughness after multiple irradiations.

[0028] Further, by introducing cerium, yttrium and erbium composite nanoparticles, the three are compatible as absorbents to form a three-dimensional radiation absorption network, which has high free radical capture capacity when irradiation penetrates the material, has a stronger absorption cross section for gamma ray high-energy particles, can effectively absorb irradiation energy and convert, reduce the depth of ray penetration into the polypropylene matrix, and can be scattered and absorbed multiple times by the radiation absorption network to gradually attenuate the energy;

[0029] Further, in order to avoid migration of the nanoparticle absorbent during the preparation of the non-woven fabric, leading to uneven dispersion, a support is introduced for coating, and then the support is modified by amino grafting. The amino group introduced by the support can react with the carbonyl group of the aromatic hydrocarbon substrate through Schiff base reaction and Michael addition reaction, so that the support is grafted on the aromatic hydrocarbon substrate, and the steric hindrance effect of the aromatic benzene ring is utilized to avoid migration of the absorbent;

[0030] At the same time, a large number of benzene rings are introduced, and the large pi bond of the benzene ring disperses the absorbed excitation energy, so that the absorbed excitation energy is transferred between molecules, and the radiation energy received by the polypropylene is transferred to the absorber molecules, thereby improving the radiation resistance of the non-woven fabric.

[0031] In addition, the carbon nanotube carrier has a free radical quenching ability and its own conjugated structure, can transfer and shield high-energy radiation energy, and improve the radiation resistance of the non-woven fabric. DETAILED DESCRIPTION

[0032] In order to further illustrate the technical means and effects adopted by the present application to achieve the predetermined object of the application, the specific embodiments, structures, features and effects according to the present application are described in detail as follows in combination with the embodiments.

[0033] Embodiment 1

[0034] A preparation method of a medical radiation-resistant non-woven fabric, comprising the following steps:

[0035] S1, the formula amount of raw materials is weighed, mixed uniformly and then put into a double screw extruder for melt extrusion to obtain a melt; the temperature of the double screw extruder is controlled at 160℃, and the screw rotation speed is 200rpm;

[0036] S2, the melt is put into a composite spinning machine, sprayed from a spinneret at a pressure of 7MPa to form a yarn, and then cooled by blowing to obtain a composite fiber;

[0037] S3, the composite fiber is pressed by a hot press roller at 80℃, and is fixed and formed at 120℃ and 10MPa to obtain the medical radiation-resistant non-woven fabric.

[0038] The raw materials include the following raw materials in mass fraction:

[0039] 100 parts by mass of polypropylene resin; 1 part by mass of radiation-resistant stabilizer; 1 part by mass of KEPUYIN J140 antibacterial agent; 0.4 parts by mass of NW16 antistatic agent; 0.6 parts by mass of antioxidant (antioxidant 626); 0.6 parts by mass of lubricant glycerol stearate; and 0.1 parts by mass of magnesium stearate.

[0040] The preparation method of the radiation-resistant stabilizer comprises the following steps:

[0041] A1, take cerium chloride, yttrium chloride, erbium chloride mixed, add octadecene and oleic acid, heated to 150℃ in nitrogen atmosphere stirring 30min, cool to room temperature, add ammonium fluoride, sodium hydroxide and methanol, stirring 10min, vacuum drying at 110℃ for 20min, then in nitrogen atmosphere, heated to 300℃ for 1h, discharge cooling, washing and centrifugal collection of solid phase, to get the absorbent; then the absorbent is dispersed in cyclohexane, to get the dispersion liquid; the cerium chloride, yttrium chloride, erbium chloride, octadecene, oleic acid, ammonium fluoride, sodium hydroxide, methanol, cyclohexane ratio is 0.06g: 0.15g: 0.008g: 14mL: 6mL: 0.15g: 0.1g: 15mL: 5mL;

[0042] A2, take hydroxylated multi-walled carbon nanotubes, anhydrous ethanol mixed ultrasonic dispersion 30min, add 3-aminopropyl triethoxysilane, heated to 40℃ water bath stirring 5h, filtration, take the solid phase vacuum drying, to get the amino grafted carbon nanotube, then blend with the dispersion liquid, ultrasonic treatment 30min, then transfer to the condition of vacuum degree (-0.098MPa) for 1h, centrifugal collection of solid phase washing, drying, to get the support; the hydroxylated multi-walled carbon nanotubes, anhydrous ethanol, 3-aminopropyl triethoxysilane, dispersion liquid ratio is 1.2g: 50mL: 1g: 15mL;

[0043] A3, take 1, 4-ketone, anhydrous ethanol, 0.01mol / L Tris buffer (pH=8.5) mixed, stirring 10min, add the support, to 65℃ condensation reflux stirring 4h, filtration, washing, drying, to get the radiation stabilizer; the 1, 4-ketone, anhydrous ethanol, Tris buffer, support ratio is 1.2g: 20mL: 15mL: 1.12g.

[0044] Example 2

[0045] A kind of medical preparation method of radiation resistant non-woven fabric, comprising the following steps:

[0046] S1, take the formula amount of raw material, after mixing uniformly, melt extrusion is put into double screw extruder, to get melt; control the temperature of double screw extruder is 180℃, screw rotation speed is 250rpm;

[0047] S2, the melt is placed in composite spinning machine, is sprayed from spinneret with 8MPa pressure, forms silk, then is cooled by air blowing, to get composite fiber;

[0048] S3, the composite fiber is pressed by hot press roll at 80℃, is fixed into shape under the condition of 120℃, 10MPa, to get the medical radiation resistant non-woven fabric.

[0049] The raw materials include the following raw materials in mass fraction:

[0050] Polypropylene resin 100 parts by mass; radiation resistant stabilizer 1.5 parts by mass; KEPUYIN® J140 antibacterial agent 1.5 parts by mass; NW16 antistatic agent 0.5 parts by mass; antioxidant (0.4 parts by mass of antioxidant 626, 0.3 parts by mass of antioxidant 1010) 0.7 parts by mass; lubricant (paraffin wax) 0.7 parts by mass; 0.1 parts by mass of magnesium stearate; 0.05 parts by mass of zinc stearate.

[0051] The preparation method of the radiation resistant stabilizer includes the following steps:

[0052] A1, take cerium chloride, yttrium chloride, erbium chloride mixture, add octadecene and oleic acid, heat to 155℃ in nitrogen atmosphere and stir for 35min, cool to room temperature, add ammonium fluoride, sodium hydroxide and methanol, stir for 15min, vacuum dry at 110℃ for 25min, then heat to 300℃ in nitrogen atmosphere for 1.5h, discharge and cool, wash and centrifuge to collect the solid phase, to get the absorbent; then disperse the absorbent in cyclohexane to get the dispersion liquid; the amount ratio of cerium chloride, yttrium chloride, erbium chloride, octadecene, oleic acid, ammonium fluoride, sodium hydroxide, methanol, cyclohexane is 0.07g:0.19g:0.0085g:15mL:6.5mL:0.155g:0.15g:15mL:5mL;

[0053] A2, take hydroxylated multi-walled carbon nanotubes and anhydrous ethanol and mix ultrasonic dispersion for 35min, add 3-aminopropyl triethoxysilane, heat and stir in water bath at 40℃ for 5.5h, filter, take the solid phase and vacuum dry, to get amino grafted carbon nanotubes, then blend with the dispersion liquid, ultrasonic treatment for 35min, then transfer to the condition of vacuum degree (-0.098MPa) for 1.5h, centrifuge, wash and dry the solid phase, to get the support; the amount ratio of hydroxylated multi-walled carbon nanotubes, anhydrous ethanol, 3-aminopropyl triethoxysilane, dispersion liquid is 1.35g:50mL:1.1g:15mL;

[0054] A3, take 1,4-ketone, anhydrous ethanol, 0.01mol / L Tris buffer (pH=8.5) and mix, stir for 15min, add the support, stir under reflux at 70℃ for 5h, filter, wash and dry the solid phase, to get the radiation resistant stabilizer; the amount ratio of 1,4-ketone, anhydrous ethanol, Tris buffer, support is 1.3g:20mL:15mL:1.13g.

[0055] Example 3

[0056] A method for preparing a medical radiation resistant non-woven fabric includes the following steps:

[0057] S1, weigh the raw materials according to the formula, mix uniformly, and then put into a twin-screw extruder for melt extrusion to obtain a melt; the temperature of the twin-screw extruder is controlled at 200℃, and the screw rotation speed is 300 rpm;

[0058] S2, put the melt into a composite spinning machine, spray out from the spinneret at a pressure of 9 MPa to form a filament, and then cool by blowing to obtain a composite fiber;

[0059] S3, press the composite fiber through a hot press roller at 80℃, and then fix and form under the condition of 120℃ and 10 MPa to obtain the medical radiation-resistant non-woven fabric.

[0060] The raw materials include the following raw materials in mass fraction:

[0061] 100 parts by mass of polypropylene resin; 2 parts by mass of radiation-resistant stabilizer; 2 parts by mass of KEPUYIN®J140 antibacterial agent; 0.6 parts by mass of NW16 antistatic agent; 0.8 parts by mass of antioxidant (antioxidant 626); 0.8 parts by mass of lubricant glycerol stearate; and 0.2 parts by mass of magnesium stearate.

[0062] The preparation method of the radiation-resistant stabilizer includes the following steps:

[0063] A1, mix cerium chloride, yttrium chloride and erbium chloride, add octadecene and oleic acid, heat to 160℃ in a nitrogen atmosphere and stir for 40 min, cool to room temperature, add ammonium fluoride, sodium hydroxide and methanol, stir for 20 min, vacuum dry at 110℃ for 30 min, then heat to 300℃ in a nitrogen atmosphere and keep for 2 h, discharge and cool, wash and centrifuge to collect the solid phase to obtain an absorbent; then disperse the absorbent in cyclohexane to obtain a dispersion liquid; the amount ratio of the cerium chloride, yttrium chloride, erbium chloride, octadecene, oleic acid, ammonium fluoride, sodium hydroxide, methanol, cyclohexane is 0.08 g:0.22 g:0.009 g:16 mL:7 mL:0.16 g:0.2 g:15 mL:5 mL;

[0064] A2, mix hydroxylated multi-walled carbon nanotubes and anhydrous ethanol and ultrasonic dispersion for 40 min, add 3-aminopropyl triethoxysilane, heat and stir in a 40℃ water bath for 6 h, filter, vacuum dry the solid phase to obtain amino-grafted carbon nanotubes, then blend with the dispersion liquid, ultrasonic treatment for 40 min, then transfer to a vacuum condition (-0.098 MPa) for 2 h, centrifuge, wash and dry the solid phase to obtain a support; the amount ratio of the hydroxylated multi-walled carbon nanotubes, anhydrous ethanol, 3-aminopropyl triethoxysilane and dispersion liquid is 1.5 g:50 mL:1.2 g:15 mL;

[0065] A3, 1,4-naphthoquinone, anhydrous ethanol, 0.01 mol / L Tris buffer (pH = 8.5) were mixed, stirred for 20 min, the support was added, and stirred at 75°C under condensation reflux for 6 h, then filtered, and the solid phase was washed and dried to obtain the radiation-resistant stabilizer; the amount of 1,4-naphthoquinone, anhydrous ethanol, Tris buffer and support was 1.4 g: 20 mL: 15 mL: 1.14 g.

[0066] Example 4

[0067] The difference from Example 2 is that the aromatic hydrocarbon substrate is benzophenone instead of 1,4-naphthoquinone.

[0068] Example 5

[0069] The difference from Example 2 is that the aromatic hydrocarbon substrate is 1,4-anthraquinone instead of 1,4-naphthoquinone.

[0070] Example 6

[0071] The difference from Example 2 is that the aromatic hydrocarbon substrate is 2-benzoquinone instead of 1,4-naphthoquinone.

[0072] Example 7

[0073] The difference from Example 2 is that no cerium chloride is added in step A1.

[0074] Example 8

[0075] The difference from Example 2 is that no yttrium chloride is added in step A1.

[0076] Example 9

[0077] The difference from Example 2 is that no erbium chloride is added in step A1.

[0078] Example 10

[0079] The difference from Example 2 is that in step A2, halloysite nanotubes are used instead of hydroxylated multi-walled carbon nanotubes as the support.

[0080] Comparative Example 1

[0081] The difference from Example 2 is that in step A2, the hydroxylated multi-walled carbon nanotubes (support) are not subjected to amino grafting modification.

[0082] Comparative Example 2

[0083] The difference from Example 2 is that the preparation method of the radiation-resistant stabilizer comprises the following steps:

[0084] A1, take cerium chloride, yttrium chloride, erbium chloride, deionized water mixed, get dispersion liquid; the cerium chloride, yttrium chloride, erbium chloride, deionized water's matching ratio is 0.07g: 0.19g: 0.0085g: 5mL;

[0085] A2, take hydroxylated multi-walled carbon nanotube, anhydrous ethanol mixed ultrasonic dispersion 35min, add 3-aminopropyl triethoxysilane, in 40℃ water bath heating stirring 5.5h, filter, take solid phase vacuum drying, get amino grafting carbon nanotube, then with dispersion liquid, ultrasonic treatment 35min, then transfer to the condition of vacuum degree (-0.098MPa) keeps 1.5h, centrifugal takes solid phase washing, dry, get load material; the hydroxylated multi-walled carbon nanotube, anhydrous ethanol, 3-aminopropyl triethoxysilane, dispersion liquid's matching ratio is 1.35g: 50mL: 1.1g: 15mL;

[0086] A3, take 1, 4-ketone, anhydrous ethanol, 0.01mol / L Tris buffer (pH = 8.5) mixed, stirring 15min, add load material, in 70℃ condensation reflux stirring 5h, filter, take solid phase washing, dry, obtain the radiation stabilizer; the 1, 4-ketone, anhydrous ethanol, Tris buffer, load material's matching ratio is 1.3g: 20mL: 15mL: 1.13g.

[0087] Comparative example 3

[0088] The difference from example 2 is that the preparation method of the radiation stabilizer comprises the following steps:

[0089] A1, take cerium chloride, yttrium chloride, erbium chloride mixed, add octadecene and oleic acid, in nitrogen atmosphere heating to 155℃ stirring 35min, cool to room temperature, add ammonium fluoride, sodium hydroxide and methanol, stirring 15min, in 110℃ vacuum drying 25min, then in nitrogen atmosphere, heating to 300℃ keeps 1.5h, discharge cooling, washing and centrifugal collection solid phase get absorbent, then dispersed in cyclohexane, get dispersion liquid; the cerium chloride, yttrium chloride, erbium chloride, octadecene, oleic acid, ammonium fluoride, sodium hydroxide, methanol, cyclohexane's matching ratio is 0.07g: 0.19g: 0.0085g: 15mL: 6.5mL: 0.155g: 0.15g: 15mL: 5mL;

[0090] A2, hydroxylated multi-walled carbon nanotubes, anhydrous ethanol were mixed and ultrasonically dispersed for 35 min, 3-aminopropyl triethoxysilane was added, and stirring was carried out at 40°C water bath for 5.5 h, filtration was carried out, the solid phase was vacuum dried to obtain amino grafted carbon nanotubes, then blended with the dispersion, ultrasonic treatment was carried out for 35 min, then transferred to a vacuum condition (-0.098 MPa) for 1.5 h, the solid phase was obtained by centrifugation, washed and dried to obtain the loaded material as a radiation resistant stabilizer; the hydroxylated multi-walled carbon nanotubes, anhydrous ethanol, 3-aminopropyl triethoxysilane, dispersion were in a ratio of 1.35 g: 50 mL: 1.1 g: 15 mL.

[0091] Comparative Example 4

[0092] The difference from Example 2 is that the preparation method of the medical radiation resistant non-woven fabric comprises the following steps:

[0093] S1, the raw materials of the formula amount were mixed uniformly and then put into a twin-screw extruder for melt extrusion to obtain a melt; the temperature of the twin-screw extruder was controlled at 180°C, and the screw rotation speed was 250 rpm;

[0094] S2, the melt was put into a composite spinning machine, and the melt was sprayed from the spinneret at a pressure of 8 MPa to form a filament, and then the filament was cooled by blowing to obtain a composite fiber;

[0095] S3, the composite fiber was pressed by a hot press roller at 80°C, and was fixed and formed at 120°C and 10 MPa to obtain the medical radiation resistant non-woven fabric.

[0096] The raw materials include the following raw materials in mass fraction:

[0097] 100 parts by mass of polypropylene resin; 1.5 parts by mass of radiation resistant stabilizer; 1.5 parts by mass of KEPUYIN®J140 antibacterial agent; 0.5 parts by mass of NW16 antistatic agent; 0.7 parts by mass of antioxidant (0.4 parts by mass of antioxidant 626, 0.3 parts by mass of antioxidant 1010); 0.7 parts by mass of lubricant (paraffin); 0.1 parts by mass of magnesium stearate; 0.05 parts by mass of zinc stearate.

[0098] The preparation method of the radiation resistant stabilizer comprises the following steps:

[0099] The cerium chloride, yttrium chloride and erbium chloride were mixed, octadecene and oleic acid were added, heated to 155°C under nitrogen atmosphere and stirred for 35 min, cooled to room temperature, ammonium fluoride, sodium hydroxide and methanol were added, stirred for 15 min, vacuum dried at 110°C for 25 min, then heated to 300°C under nitrogen atmosphere for 1.5 h, the material was discharged and cooled, washed and centrifuged to collect the solid phase to obtain the absorbent as a radiation resistant stabilizer.

[0100] Performance test

[0101] The non-woven fabrics prepared in Examples 1-10 and Comparative Examples 1-4 were exposed to a 50kGy gamma radiation environment for multiple irradiation experiments, and the non-woven fabrics were tested for performance after each irradiation, and the test results are shown in Table 1.

[0102] Table 1 Performance of non-woven fabrics prepared in Examples 1-10 and Comparative Examples 1-4

[0103]

[0104] As can be seen from Table 1, the non-woven fabrics prepared in Examples 1-10 have good radiation resistance; among them, the non-woven fabric prepared according to the formula of Example 2 still has the best breaking resistance and good toughness after 100 irradiations.

[0105] In addition, Comparative Example 1 did not perform amino grafting modification on the hydroxylated multi-walled carbon nanotubes (supporting agent) based on Example 2, resulting in migration during processing and reducing the radiation resistance of the non-woven fabric; in Comparative Example 2, the surface treatment of the absorber was not performed, resulting in easy agglomeration of the absorber and reducing the radiation resistance of the non-woven fabric; in Comparative Example 3, the supporting agent was not grafted with an aromatic hydrocarbon substrate containing a benzene ring, reducing the radiation resistance of the non-woven fabric; and in Comparative Example 4, only the absorber was added, and it was difficult to achieve good radiation resistance.

[0106] The above is only a preferred embodiment of the present application, and does not limit the present application in any form. Although the present application has been disclosed as above with a preferred embodiment, it is not intended to limit the present application. Any person skilled in the art can make some changes or modifications to the above disclosed technical content to obtain equivalent embodiments with equivalent changes, without departing from the technical solution of the present application. Any modification, equivalent change and modification of the above embodiments according to the technical essence of the present application, as long as it does not deviate from the technical solution of the present application, still belongs to the scope of the technical solution of the present application.

Claims

1. A medical radiation resistant nonwoven fabric, characterized by, The raw materials include the following quality parts: polypropylene resin 100 parts by mass; radiation resistant stabilizer 1-2 parts by mass; antibacterial agent 1-2 parts by mass; antistatic agent 0.4-0.6 parts by mass; antioxidant 0.6-0.8 parts by mass; lubricant 0.6-0.8 parts by mass; stearate 0.1-0.2 parts by mass; The radiation resistant stabilizer is prepared by grafting amino groups on a carbonyl-containing aromatic hydrocarbon substrate with a support coated with an absorbent; The preparation method of the radiation resistant stabilizer includes the following steps: A1, take cerium chloride, yttrium chloride, erbium chloride, add octadecene and oleic acid, heat to 150℃ under nitrogen atmosphere and stir for 30 min, cool to room temperature, add ammonium fluoride, sodium hydroxide and methanol, stir for 10 min, vacuum dry at 110℃ for 20 min, then heat to 300℃ under nitrogen atmosphere and keep for 1 h, discharge and cool, wash and centrifuge to collect the solid phase to obtain the absorbent; then disperse the absorbent in cyclohexane to obtain a dispersion liquid; the amount ratio of the cerium chloride, yttrium chloride, erbium chloride, octadecene, oleic acid, ammonium fluoride, sodium hydroxide, methanol, cyclohexane is 0.06 g:0.15 g:0.008 g:14 mL:6 mL:0.15 g:0.1 g:15 mL:5 mL; A2, take the hydroxylated multi-walled carbon nanotubes and anhydrous ethanol, ultrasonic dispersion for 30 min, add 3-aminopropyl triethoxysilane, heat and stir in a 40℃ water bath for 5 h, filter, vacuum dry the solid phase to obtain amino-grafted carbon nanotubes, then blend with the dispersion liquid, ultrasonic treatment for 30 min, then transfer to a condition of vacuum degree-0.098 MPa for 1 h, centrifuge to take the solid phase, wash and dry to obtain the support; the amount ratio of the hydroxylated multi-walled carbon nanotubes, anhydrous ethanol, 3-aminopropyl triethoxysilane, dispersion liquid is 1.2 g:50 mL:1 g:15 mL; A3, take 1,4-crotononitrile, anhydrous ethanol, Tris buffer solution, stir for 10 min, add the support, stir under reflux condensation at 65℃ for 4 h, filter, wash and dry the solid phase to obtain the radiation resistant stabilizer; the amount ratio of the 1,4-crotononitrile, anhydrous ethanol, Tris buffer solution, support is 1.2 g:20 mL:15 mL:1.12 g; the concentration of the Tris buffer solution is 0.01 mol / L, pH=8.5; Or, the preparation method of the radiation resistant stabilizer includes the following steps: A1, take cerium chloride, yttrium chloride, erbium chloride mixture, add octadecene and oleic acid, heat to 155℃ under nitrogen atmosphere stirring 35min, cool to room temperature, add ammonium fluoride, sodium hydroxide and methanol, stirring 15min, vacuum drying at 110℃ for 25min, then under nitrogen atmosphere, heat to 300℃ for 1.5h, discharge cooling, washing and centrifugal collection of solid phase, to get the absorbent; then the absorbent is dispersed in cyclohexane to obtain a dispersion liquid; the amount ratio of cerium chloride, yttrium chloride, erbium chloride, octadecene, oleic acid, ammonium fluoride, sodium hydroxide, methanol, cyclohexane is 0.07g:0.19g:0.0085g:15mL:6.5mL:0.155g:0.15g:15mL:5mL; A2, take hydroxylated multi-walled carbon nanotubes, anhydrous ethanol mixed ultrasonic dispersion 35min, add 3-aminopropyl triethoxysilane, heating stirring at 40℃ water bath for 5.5h, filtration, vacuum drying of solid phase, to get amino grafted carbon nanotubes, then blend with dispersion liquid, ultrasonic treatment 35min, then transfer to the condition of-0.098MPa vacuum degree for 1.5h, centrifugal collection of solid phase washing, drying, to get the support; the amount ratio of hydroxylated multi-walled carbon nanotubes, anhydrous ethanol, 3-aminopropyl triethoxysilane, dispersion liquid is 1.35g:50mL:1.1g:15mL; A3, take any one of 1, 4-crotonophenone, benzophenone, 1, 4-anthrachinone, 2-benzoquinone and anhydrous ethanol, Tris buffer solution mixed, stirring 15min, add the support, stirring at 70℃ condensation reflux for 5h, suction filtration, washing and drying of solid phase, to get the radiation resistant stabilizer; the amount ratio of 1, 4-crotonophenone, anhydrous ethanol, Tris buffer solution, support is 1.3g:20mL:15mL:1.13g; the amount ratio of benzophenone, anhydrous ethanol, Tris buffer solution, support is 1.3g:20mL:15mL:1.13g; the amount ratio of 1, 4-anthrachinone, anhydrous ethanol, Tris buffer solution, support is 1.3g:20mL:15mL:1.13g; the amount ratio of 2-benzoquinone, anhydrous ethanol, Tris buffer solution, support is 1.3g:20mL:15mL:1.13g; the concentration of Tris buffer solution is 0.01mol / L, pH=8.5; Or, the preparation method of the radiation resistant stabilizer comprises the following steps: A1, take cerium chloride, yttrium chloride, erbium chloride mixture, add octadecene and oleic acid, heated to 160 DEG C in nitrogen atmosphere stirring 40 min, cool to room temperature, add ammonium fluoride, sodium hydroxide and methanol, stirring 20 min, vacuum drying at 110 DEG C 30 min, then in nitrogen atmosphere, heated to 300 DEG C 2h, discharge cooling, washing and centrifugal collection of solid phase, to get the absorbent, then the absorbent is dispersed in cyclohexane, to get the dispersion liquid, the cerium chloride, yttrium chloride, erbium chloride, octadecene, oleic acid, ammonium fluoride, sodium hydroxide, methanol, cyclohexane ratio is 0.08g: 0.22g: 0.009g: 16mL: 7mL: 0.16g: 0.2g: 15mL: 5mL; A2, take hydroxylated multi-walled carbon nanotubes, anhydrous ethanol mixed ultrasonic dispersion 40 min, add 3-aminopropyl triethoxysilane, heated to 40 DEG C water bath stirring 6h, filtration, take solid phase vacuum drying, to get the amino grafted carbon nanotube, then with the dispersion liquid, ultrasonic treatment 40 min, then transfer to the condition of-0.098MPa for 2h, centrifugal collection of solid phase washing, drying, to get the support; The hydroxylated multi-walled carbon nanotubes, anhydrous ethanol, 3-aminopropyl triethoxysilane, dispersion liquid ratio is 1.5g: 50mL: 1.2g: 15mL; A3, take 1, 4-ketone, anhydrous ethanol, Tris buffer solution mixing, stirring 20 min, add the support, to 75 DEG C condensation reflux stirring 6h, suction filtration, washing, drying, to get the radiation stabilizer; The 1, 4-ketone, anhydrous ethanol, Tris buffer solution, support ratio is 1.4g: 20mL: 15mL: 1.14g; The concentration of Tris buffer solution is 0.01mol / L, pH = 8.5; Or, the preparation method of the radiation stabilizer comprises the following steps: A1, take cerium chloride, yttrium chloride, erbium chloride mixture, add octadecene and oleic acid, heated to 155 DEG C in nitrogen atmosphere stirring 35 min, cool to room temperature, add ammonium fluoride, sodium hydroxide and methanol, stirring 15 min, vacuum drying at 110 DEG C 25 min, then in nitrogen atmosphere, heated to 300 DEG C 1.5h, discharge cooling, washing and centrifugal collection of solid phase, to get the absorbent, then the absorbent is dispersed in cyclohexane, to get the dispersion liquid, the cerium chloride, yttrium chloride, erbium chloride, octadecene, oleic acid, ammonium fluoride, sodium hydroxide, methanol, cyclohexane ratio is 0.07g: 0.19g: 0.0085g: 15mL: 6.5mL: 0.155g: 0.15g: 15mL: 5mL; A2, taking halloysite nanotubes, anhydrous ethanol, and ultrasonic dispersion for 35 min, adding 3-aminopropyl triethoxysilane, heating and stirring at 40 DEG C water bath for 5.5 h, filtering, taking the solid phase vacuum drying, obtaining amino grafted halloysite nanotubes, then blending with the dispersion, ultrasonic treatment for 35 min, then transferred to the condition of-0.098 MPa vacuum for 1.5 h, centrifugal taking solid phase washing, drying, obtaining the support; the halloysite nanotubes, anhydrous ethanol, 3-aminopropyl triethoxysilane, dispersion of the amount ratio is 1.35 g: 50 mL: 1.1 g: 15 mL; A3, taking 1, 4-ketone, anhydrous ethanol, Tris buffer mixed, stirring for 15 min, adding the support, condensation reflux stirring at 70 DEG C for 5 h, suction filtration, taking the solid phase washing, drying, obtaining the radiation stabilizer; the 1, 4-ketone, anhydrous ethanol, Tris buffer, the amount ratio of the support is 1.3 g: 20 mL: 15 mL: 1.13 g; the concentration of the Tris buffer is 0.01 mol / L, pH = 8.

5.

2. The medical radiation resistant nonwoven fabric according to claim 1, wherein The antibacterial agent is a guanidine antibacterial agent.

3. The medical radiation resistant nonwoven fabric according to claim 1, wherein The antistatic agent is NW16 antistatic agent.

4. The medical radiation resistant nonwoven fabric according to claim 1, wherein The antioxidant is selected from at least one of antioxidant 626, antioxidant 1010.

5. The medical radiation resistant nonwoven fabric according to claim 1, wherein The lubricant is any one of glycerol stearate and paraffin.

6. The medical radiation resistant nonwoven fabric according to claim 1, wherein The stearate is at least one of magnesium stearate, zinc stearate, calcium stearate.

7. A method for producing the medical radiation resistant nonwoven fabric as claimed in any one of claims 1 to 6, characterized by, The method comprises the following steps: S1, the formula amount of raw materials is mixed uniformly and then put into a double screw extruder for melt extrusion, obtaining a melt; the temperature of the double screw extruder is controlled at 160-200 DEG C, and the screw rotation speed is 200-300 rpm; S2, the melt is put into a composite spinning machine, sprayed from the spinneret at a pressure of 7-9 MPa, forming a yarn, and then cooled by blowing, obtaining a composite fiber; S3, the composite fiber is pressed by a hot press roller at 80 DEG C, and fixedly formed at 120 DEG C and 10 MPa, obtaining the medical radiation resistant non-woven fabric.

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