Applicating oil and preparation method thereof

Abstract

The invention discloses inunction oil and a preparation method thereof, and relates to the technical field of health care coating products. The Tibetan medicine active volatile oil composition is prepared from a Tibetan medicine active volatile oil component and a low-sensitivity compound base oil component in a weight ratio of 1: 10, wherein the Tibetan medicine active volatile oil component is prepared from the following raw materials in a weight range through enzymolysis pretreatment and extraction: 1200 to 1600g of dried ginger, 1000 to 1300g of fructus piperis longi, 1200 to 1600g of pepper and 200 to 300g of pepper; the extraction rate of the Tibetan medicine active volatile oil component is larger than or equal to 0.58 ml / 100g, the low-sensitivity compound base oil component is formed by mixing refined first-grade peanut oil and cold-pressed sunflower seed oil according to the weight ratio of 6: 4, the content of aflatoxin B in the refined first-grade peanut oil is smaller than or equal to 5 mu g / kg, and the content of unsaturated fatty acid in the cold-pressed sunflower seed oil is larger than or equal to 88%. The rhizoma zingiberis and the fructus piperis longi are smashed into 1-3 mm coarse powder, 8 times of water is combined, distillation extraction is conducted for 5 hours, the extraction amount of volatile oil reaches 0.52-0.53 ml / 100 g of raw materials, the extraction amount is increased by about 80% compared with a traditional decoction piece soaking method (0.28-0.29 ml / 100 g of raw materials), the utilization rate of effective components of Tibetan medicine is greatly increased, and the health-care effect after inunction is guaranteed.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of health care coating products, in particular to a coating oil and a preparation method thereof. BACKGROUND

[0002] As an external health care product, the core requirement of the coating oil is the balance between "efficacy" and "use experience": it needs to rely on functional ingredients (such as Tibetan medicine volatile oil) to achieve health care effects, and at the same time, it needs to ensure smoothness and skin tolerance during coating through base oil. The same coating oils on the market have the following technical defects: Insufficient extraction of Tibetan medicine active ingredients: most products directly mix Tibetan medicine decoction pieces with base oil for soaking, without optimizing the processing of raw materials such as dried ginger (rhizome type, tight texture) and piper longum (fruit cluster type, volatile oil wrapped inside the tissue), resulting in low volatile oil extraction rate (only 0.28-0.29ml / 100g of raw materials), insufficient utilization of active ingredients, and limited health care effect after coating; Poor base oil adaptability: common choices include camellia seed oil (too high in cost, not suitable for mass production in a general consumer context), rapeseed oil (poor oxidation stability, prone to spoilage and odor, and inherent odor interferes with the efficacy aroma of Tibetan medicine volatile oil), or olive oil (too high in viscosity, strong oily residue on the skin after coating, and the fruity aroma of olive oil itself masks the original aroma of Tibetan medicine), making it difficult to achieve a balance in "skin feel, cost, stability, and efficacy retention".

[0003] Therefore, developing a Tibetan medicine compound coating oil with "high volatile oil extraction rate, adaptive base oil, stable compounding system, and safe controllability" is the key direction to solve the problems of the prior art. SUMMARY

[0004] The purpose of the present application is to improve the extraction efficiency of volatile oil in Zanthoxylum bungeanum, Piper nigrum, dried ginger and piper longum, fully release the active ingredients of Tibetan medicine, and ensure the health care effect of the coating oil. The present application provides a coating oil and a preparation method thereof.

[0005] In order to achieve the above purpose, the present application specifically adopts the following technical scheme: A coating oil and a preparation method thereof, comprising Tibetan medicine active volatile oil components and low-sensitivity compounding base oil components in a weight ratio of 1:10, the Tibetan medicine active volatile oil components being extracted from 1200-1600g of dried ginger, 1000-1300g of piper longum, 1200-1600g of Piper nigrum, and 200-300g of Zanthoxylum bungeanum after enzymatic pretreatment of the raw materials in the above weight ranges; the extraction rate of the Tibetan medicine active volatile oil components is ≥0.58ml / 100g, and the low-sensitivity compounding base oil components are a mixture of refined first-grade peanut oil and cold-pressed sunflower seed oil in a weight ratio of 6:4, wherein the content of aflatoxin B1 in the refined first-grade peanut oil is ≤5μg / kg, and the content of unsaturated fatty acids in the cold-pressed sunflower seed oil is ≥88%.

[0006] Further, the low-sensitivity compound base oil component has a kinematic viscosity at 25°C of 30-36 mm2 / s and a total number of colonies ≤5 CFU / g.

[0007] A preparation method of the rubbing oil according to any one of claims 1-2, comprising the following steps: Step 1: after impurity removal, dry ginger is soaked for 18-22 minutes, and then is thoroughly moistened until there is no white core in the cross section. The ginger is then cut into 2-3 mm thick slices and is dried at 65-70°C until the moisture content is ≤10%. After impurity removal, cubeb is crushed to a particle size of 1.5-3 mm and is passed through a 20-mesh sieve. Pepper is passed through a 30-mesh sieve to remove impurities. Zanthoxylum bungeanum is sorted to remove pepper seeds and fruit stalks, and the impurity content is controlled to be ≤0.5%; Step 2: the processed dry ginger and cubeb are crushed into 1-2 mm coarse powder, and are mixed with pepper and Zanthoxylum bungeanum. 0.4-0.6% of a compound cellulase is added, and 4 times the amount of purified water is added. Enzymolysis is performed at 52-55°C for 1.2-1.5 hours, and inactivation is performed at 98°C for 8-10 minutes. 4 times the amount of purified water is added, and distillation extraction is performed using the methanol method for 5-5.5 hours. The volatile oil is collected and is filtered through a 0.22 μm microporous filter; Step 3: the qualified refined first-grade peanut oil and cold-pressed sunflower seed oil are weighed according to a weight ratio of 6:4, and are stirred at 25-28°C and 300-350 r / min for 15-20 minutes to form a compound base oil; Step 4: the raw materials are weighed according to a weight ratio of volatile oil: compound base oil = 1:10. The compound base oil is stirred at 25-28°C and 400-450 r / min, and the volatile oil is added dropwise. After stirring for 40-50 minutes, high-speed homogenization is performed at 18,000-22,000 r / min for 8-10 minutes to obtain a semi-finished product; Step 5: the semi-finished product is detected for a total number of colonies ≤10 CFU / g, a number of molds and yeasts ≤5 CFU / g, and a content of heavy metal lead ≤0.1 mg / kg. After passing the detection, the semi-finished product is aseptically packaged into brown glass bottles that have been sterilized at 121°C, and is sealed and labeled.

[0008] Further, in step 2, the compound cellulase is composed of cellulase and hemicellulase at a weight ratio of 1:1, and has an enzyme activity ≥6000 U / g. During the enzymolysis process, stirring is performed at a speed of 200-250 r / min for 30 seconds every 15 minutes.

[0009] Further, in step 2, the distillation extraction is controlled at a distillation speed of 2-2.5 drops per second. After the extraction is completed, the volatile oil needs to be stored at 4-6°C in a cold and sealed state, and the storage time is not more than 48 hours.

[0010] Further, the refined first-grade peanut oil and the cold-pressed sunflower seed oil need to be detected for aflatoxin B1 before use. The content of aflatoxin B1 in peanut oil is ≤5 μg / kg, and the content of aflatoxin B1 in sunflower seed oil is ≤2 μg / kg.

[0011] Further, in the step 4, the dropping speed of the volatile oil is 1.2-1.5 ml / min, and the high-speed homogenization is performed twice, each time for 4-5 minutes, and the interval between the two times is 2 minutes.

[0012] Further, in the step 5, the semi-finished product heavy metal detection further includes that the arsenic content is ≤0.05 mg / kg.

[0013] Further, in the step 5, the specification of the brown glass bottle is 5 ml, 10 ml or 20 ml, and the sterile filling is performed in a ten-thousand-level clean workshop, and the filling precision is controlled to be ±0.3 ml.

[0014] Further, in the step 5, the label marking content includes the proportion of the compounded base oil (peanut oil: sunflower seed oil = 6:4), the shelf life of 24 months, and the storage temperature of ≤25℃.

[0015] The beneficial effects of the present application are as follows: 1. In the present application, the dried ginger and the cubeb are crushed into 1-3 mm coarse powder, 8 times of water is added, and the volatile oil is extracted by distillation for 5 hours, so that the extraction amount of the volatile oil reaches 0.52-0.53 ml / 100 g of raw material, which is about 80% higher than that of the traditional decoction piece immersion method (0.28-0.29 ml / 100 g of raw material), and the utilization rate of the effective components of the Tibetan medicine is greatly improved, thereby ensuring the health care effect after rubbing. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 is the preparation flowchart of the present application. DETAILED DESCRIPTION

[0017] In order to make the purpose, technical scheme and advantages of the embodiments of the present application clearer, the technical scheme in the embodiments of the present application will be described clearly and completely below in combination with the drawings in the embodiments of the present application.

[0018] The rubbing oil and the preparation method thereof provided in the present embodiment are mainly used to solve the problems of improving the extraction efficiency of volatile oil in pepper, pepper, dried ginger and cubeb, fully releasing the effective components of the Tibetan medicine, and ensuring the health care effect of the rubbing oil, and the following technical scheme is provided, which will be described in detail as follows: A rubbing oil, which is compounded by a Tibetan medicine volatile oil component and a base oil component according to a weight ratio of 1:10, and the specific composition and requirements of each component are as follows: the Tibetan medicine volatile oil component is obtained by extracting the following fixed weight of Tibetan raw materials, and the raw material formula is: dried ginger 1500 g, cubeb 1250 g, pepper 1500 g, and pepper 250 g; the base oil component adopts refined first-grade peanut oil, which needs to meet the national standard, wherein the content of aflatoxin B1 is ≤5 μg / kg, the content of allergen meets the relevant standards of national food safety and cosmetic raw material safety, and the skin contact safety is ensured.

[0019] The preparation method of the rubbing oil is as follows It mainly includes four core steps of Tibetan medicine decoction piece processing, volatile oil extraction, compound mixing, and sterile packaging, and the specific operation is as follows: Step 1: Tibetan medicine decoction piece processing Dried ginger: According to the processing method of dried ginger decoction piece in Chinese Pharmacopoeia, the operation process is as follows: first, remove the impurities (such as moldy blocks, mud and sand) in the raw material of dried ginger, add purified water and soak for 15-20 minutes (the surface of the raw material is moistened and there is no dry hard block), then wash and put it in the wet medicine machine to make it wet (the wetness judgment standard: cut the raw material section without dry core, uniform texture), then cut it into 2-4 mm thick slices or blocks with a slicing machine, and then put it into a drying oven at 60-70℃ to dry to a moisture content of ≤12%, ready for use; Piper longum: According to the processing method of piper longum decoction piece in Chinese Pharmacopoeia, first remove the impurities (such as broken fruit clusters and foreign matter) by hand, then crush it into a powder with a particle size of 2-5 mm with a universal crusher, and then use it; Pepper: According to the processing method of pepper decoction piece in Chinese Pharmacopoeia, pass the pepper raw material through a 40-mesh standard sieve to remove the fine powder under the sieve and the impurities (such as stones and worm-eaten particles) on the sieve, and then use it; Zanthoxylum bungeanum: According to the processing method of Zanthoxylum bungeanum decoction piece in Chinese Pharmacopoeia, use manual selection to remove impurities such as pepper eyes (Zanthoxylum bungeanum seeds), fruit stalks and moldy fruits, and then use it.

[0020] Step 2: Tibetan medicine volatile oil extraction Mix the raw materials: grind the processed dried ginger (slices / blocks) and piper longum (powder) into coarse powder with a particle size of 1-3 mm with a crusher, then mix them with the processed pepper and Zanthoxylum bungeanum to get a total weight of 4500g of mixed raw materials; Distillation extraction: add 8 times the amount of purified water (based on the total weight of the mixed raw materials, i.e. 36000g) to the mixed raw materials, transfer the mixture to a round-bottom flask, connect the volatile oil detector and condenser tube according to the 2025 edition of Chinese Pharmacopoeia (volatile oil determination method), heat the round-bottom flask for distillation, and control the distillation speed at 2-3 drops per second during the process. Continue distillation for 5 hours; Impurity removal: after distillation, collect the upper oil phase (i.e. Tibetan medicine volatile oil) in the volatile oil detector, filter it with a 0.22μm microporous filter to remove any fine powder impurities that may be left in the oil phase, and get clear volatile oil, which is sealed and refrigerated (4-8℃) for standby.

[0021] Step 3: Compound mixing of rubbing oil Raw material weighing: according to the weight ratio of "Tibetan medicine volatile oil: refined first-grade peanut oil = 1:10", weigh the standby clear volatile oil and refined first-grade peanut oil respectively; Constant temperature stirring: the weighed refined first-grade peanut oil is added into a sterile constant temperature stirring container, the temperature of the stirring container is set to 25-30℃, the stirring speed is 300-500 r / min, and the stirring device is turned on to keep the peanut oil in uniform stirring state; Mixing and homogenization: the weighed Tibetan medicine volatile oil is slowly added into the stirring peanut oil at a drop rate of 1-2 ml / min, after the drop is completed, the stirring parameters remain unchanged, and stirring is continued for 30-60 minutes, until the oil phase system is uniform and transparent, without visible oil droplets or stratification phenomenon, and the stirring is stopped, to obtain the semi-finished product of the rubbing oil.

[0022] Step 4: sterile dispensing Container preparation: clean and dry brown glass bottles (specifications can be selected as 5ml, 10ml or 20ml, brown bottles can avoid light and prevent volatile oil from oxidizing and deteriorating) are selected, sterilized by 121℃ high-pressure steam for 30 minutes, and then cooled to room temperature for standby; Sterile filling: a sterile filling machine (filling precision control is ±0.5ml) is used to dispense the semi-finished product of the rubbing oil into the sterilized brown glass bottles, and the filling amount of each bottle is determined according to the specification of the glass bottle (for example, 10ml specification bottle is filled with 10g rubbing oil); Sealing and labeling: after the dispensing is completed, the bottle opening is immediately sealed with a butyl rubber plug, and then an aluminum-plastic combined cover is added and pressed tightly; the label is pasted on the bottle body, and the product name is clearly marked on the label.

[0023] Example 1: preparation of rubbing oil by optimal process Preparation of Tibetan medicine decoction pieces Dried ginger: 1500g of dried ginger raw material is taken, and mildewed blocks, mud and other impurities are manually removed; after being washed, it is put into a medicine moistening machine for moistening (the cut section is free of dry core); it is cut into 3mm thick slices by a slicing machine, and then placed in a 65℃ drying oven for drying until the moisture content is 10%, for standby; Piper longum: 1250g of piper longum is taken, and broken fruit clusters and foreign matters are manually removed; it is crushed into 3mm particle size of crushed powder by a universal crusher, for standby; Pepper: 1500g of pepper is taken, and the crushed powder and stones, worm-eaten particles on the screen are removed by passing through a 40-mesh standard screen, for standby; Zanthoxylum bungeanum: 250g of Zanthoxylum bungeanum is taken, and pepper stems, fruit stalks and mildewed fruits are manually removed, for standby.

[0024] Extraction of Tibetan medicine volatile oil The dried ginger slices and piper longum crushed powder are respectively crushed into 2mm particle size of coarse powder, and then mixed with pepper and Zanthoxylum bungeanum uniformly to obtain 4500g of mixed raw material; To the mixed raw materials, 36000 g of purified water was added, and transferred to a 50 L round-bottom flask. The oil measuring device was connected to the condenser according to the method of Pharmacopoeia 2025 Edition General Chapter 2204A, and heated distillation was performed with the control of the distillation speed of 2.5 drops per second, and the extraction was continued for 5 hours; The volatile oil 23.6 ml was collected and filtered with a 0.22 μm microporous filter membrane to obtain a clear volatile oil, which was stored at 4°C for standby use.

[0025] Compound mixing of the rubbing oil 23.6 ml of volatile oil (density 0.9 g / ml, weight 21.24 g) was weighed, and 212.4 g of refined first-grade peanut oil (1:10 weight ratio) was weighed. The peanut oil was added to a 500 ml sterile constant temperature stirring container, and the stirring was started with the temperature set at 28°C and the rotation speed set at 400 r / min; The volatile oil was added dropwise at a speed of 1.5 ml / min, and after the dropwise addition was completed, the stirring was continued for 45 minutes to obtain a uniform transparent rubbing oil semi-finished product.

[0026] Sterile packaging A 10 ml brown glass bottle was selected, and high pressure sterilization was performed at 121°C for 30 minutes, and then cooled to room temperature; The rubbing oil semi-finished product was packaged into the brown bottle by using a sterile filling machine, and each bottle was filled with 10 g; After the bottle opening was sealed, a label was attached, and product information and warning words were marked, and the preparation was completed.

[0027] Comparative Example 1: Preparation of rubbing oil without pulverized dried ginger and piper longum The difference from Example 1 is that the dried ginger and piper longum are not pulverized into coarse powder, but the dried ginger thick slices (3 mm) and intact piper longum fruit spikes are directly mixed with pepper and prickly ash for distillation extraction, and the remaining steps are completely the same. Results: The volatile oil extraction amount is only 12.8 ml, the extraction rate is reduced by 45.8% compared with Example 1, and the effective odor of Tibetan medicine is obviously lighter during rubbing.

[0028] Comparative Example 2: Preparation of rubbing oil using olive oil as base oil The difference from Example 1 is that the base oil is replaced by extra virgin olive oil, and the remaining steps are completely the same. Results: The kinematic viscosity of the rubbing oil at 25°C reaches 65 mm² / s, and the skin is obviously oily after rubbing; the fruity aroma of olive oil itself covers the pungent smell of Tibetan medicine, and the effective odor is lost; after the product is placed for 6 months, a 1 mm thick layered oil phase appears at the bottom of the bottle.

[0029] The foregoing description of the disclosed embodiments enables a person skilled in the art to make or use the application. Modifications of these embodiments will occur to persons of skill in the art, and that the appended claims are intended to cover all such modifications that do not depart from the true spirit and scope of the application. Therefore, the application is not limited to the embodiments shown but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A racing oil characterized by, The application relates to a low-allergy compounded base oil component, which comprises active volatile oil components of Tibetan medicine and low-allergy compounded base oil components, wherein the active volatile oil components of Tibetan medicine are extracted from raw materials in the following weight ranges after enzymatic pretreatment: 1200-1600g of dried ginger, 1000-1300g of piper longum, 1200-1600g of pepper and 200-300g of zanthoxylum bungeanum; the extraction rate of the active volatile oil components of Tibetan medicine is greater than or equal to 0.58ml / 100g; and the low-allergy compounded base oil components are prepared by mixing refined first-grade peanut oil and cold-pressed sunflower seed oil at a weight ratio of 6:4, wherein the content of aflatoxin B1 in the refined first-grade peanut oil is less than or equal to 5ug / kg, and the content of unsaturated fatty acid in the cold-pressed sunflower seed oil is greater than or equal to 88%.

2. The coating composition of claim 1, wherein The 25 DEG C kinematic viscosity of the low-allergy compounded base oil component is 30-36mm2 / s, and the total number of colonies is less than or equal to 5CFU / g.

3. A method of preparing a spread according to any one of claims 1-2, characterized in that, The application further relates to a preparation method of the low-allergy compounded base oil component. Step 1: after impurity removal, the dried ginger is slightly soaked for 18-22 minutes, is thoroughly moistened until the cross section is free of white core, is cut into 2-3mm-thick pieces, and is dried at 65-70 DEG C until the moisture content is less than or equal to 10%; the piper longum is crushed to a particle size of 1.5-3mm after impurity removal and is passed through a 20-mesh sieve; the pepper is passed through a 30-mesh sieve to remove impurities; and the zanthoxylum bungeanum is selected to remove pepper core and fruit stalks, and the impurity content is controlled to be less than or equal to 0.5%; Step 2: the prepared dried ginger, piper longum and pepper are mixed, 0.4-0.6% of compound cellulase and 4 times of purified water are added, enzymatic hydrolysis is carried out at 52-55 DEG C for 1.2-1.5 hours, and inactivation is carried out at 98 DEG C for 8-10 minutes; 4 times of purified water is added, and volatile oil is collected by using the methanol method for distillation extraction for 5-5.5 hours, and the volatile oil is filtered through a 0.22mu m microporous filter membrane; Step 3: the qualified refined first-grade peanut oil and cold-pressed sunflower seed oil are weighed at a weight ratio of 6:4, are stirred at 25-28 DEG C and a speed of 300-350r / min for 15-20 minutes, and the compounded base oil is formed; Step 4: the raw materials are weighed according to the volatile oil: compounded base oil = 1:10, the compounded base oil is stirred at 25-28 DEG C and a speed of 400-450r / min, the volatile oil is added dropwise and stirred for 40-50 minutes, and then high-speed homogenization is carried out at a speed of 18000-22000r / min for 8-10 minutes, so that the semi-finished product is obtained; Step 5: the total number of colonies of the semi-finished product is detected to be less than or equal to 10CFU / g, the number of molds and yeasts is less than or equal to 5CFU / g, and the content of heavy metal lead is less than or equal to 0.1mg / kg, and after the semi-finished product is qualified, it is aseptically packaged into brown glass bottles sterilized at 121 DEG C, and is sealed and labeled.

4. The method of claim 3, wherein the oil-based paint is prepared by adding the pigment to the oil-based paint, and then adding the dispersant to the oil-based paint. In step 2, the compound cellulase is composed of cellulase and hemicellulase at a weight ratio of 1:1, the enzyme activity is greater than or equal to 6000U / g, and the stirring speed is 200-250r / min for 30 seconds every 15 minutes during the enzymatic hydrolysis process.

5. The method of claim 3, wherein the oil-based coating is prepared by mixing the oil-based coating material and the additive in a ratio of 1:0.1 to 1:0.

5. In step 2, the distillation extraction speed is controlled to be 2-2.5 drops per second, and the volatile oil needs to be stored at 4-6 DEG C in a cold and sealed manner after extraction, and the storage time is not more than 48 hours.

6. The method of claim 3, wherein the oil-based coating is prepared by mixing the oil-based coating material and the additive in a ratio of 1:0.1 to 1:0.

5. In step 3, the refined first-grade peanut oil and cold-pressed sunflower seed oil need to be detected for aflatoxin B1 before use, and the content of aflatoxin B1 in the peanut oil is less than or equal to 5ug / kg, and the content of aflatoxin B1 in the sunflower seed oil is less than or equal to 2ug / kg.

7. The method of claim 3, wherein the oil-based paint is prepared by adding the pigment to the oil-based paint, and then adding the dispersant to the oil-based paint. In the step 4, the dropping speed of the volatile oil is 1.2-1.5 ml / min, the high-speed homogenization is performed twice, each time for 4-5 minutes, and the interval between the two times is 2 minutes.

8. The method of claim 3, wherein the oil-based coating is prepared by mixing the oil-based coating material and the additive in a ratio of 1:0.1 to 1:0.

5. In the step 5, the semi-finished product heavy metal detection further includes that the arsenic content is less than or equal to 0.05 mg / kg.

9. The method of claim 3, wherein the oil-based paint is prepared by adding the pigment to the oil-based paint, and then adding the dispersant to the oil-based paint. In the step 5, the specification of the brown glass bottle is 5 ml, 10 ml or 20 ml, the sterile filling is performed in a ten-thousand-level clean workshop, and the filling precision is controlled to be ±0.3 ml.

10. The method of claim 3, wherein the oil-based coating is prepared by the steps of: In the step 5, the label marking content includes the proportion of the compounded base oil (peanut oil: sunflower oil = 6:4), the shelf life of 24 months, and the storage temperature of less than or equal to 25℃.

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