Traditional Chinese medicine composition for improving stagnant water intermingled shoulder coagulation

Abstract

The invention provides a traditional Chinese medicine composition for improving blood stasis and water accumulation type shoulder coagulation. The traditional Chinese medicine composition is prepared from black prepared common monkshood daughter root, poria cocos, fresh ginger, polyporus umbellatus, rhizoma alismatis, honey-fried licorice root, pericarpium citri reticulatae, radix paeoniae rubra, rhizoma atractylodis macrocephalae, rhizoma wenyujin concisum, notopterygium root, cassia twig, astragalus membranaceus and garden balsam stem. The black prepared common monkshood daughter root has the effects of inducing diuresis to alleviate edema and is The poria cocos, the polyporus umbellatus and the rhizoma alismatis are used as ministerial drugs for clearing damp and promoting diuresis. The cassia twig can warm and dredge meridians and strengthen yang and qi, and the medicine efficacy is good on the upper limbs, shoulders and arms and helps the black prepared common monkshood daughter root to warm water dampness; radix astragali tonifies qi and promotes water circulation, and poria cocos and rhizoma atractylodis macrocephalae promote diuresis and alleviate edema; the rhizoma seu radix notopterygii is matched with the rhizoma curcumae longae and the herba speranskiae tuberculatae, so that the effect of removing arthralgia is enhanced, the upper limb arthralgia syndrome is improved, radix paeoniae rubra has the effects of activating blood, removing stasis and relieving pain; the ginger is matched with the black prepared aconite root, so that the effects of warming yang and promoting diuresis are enhanced; the pericarpium citri reticulatae is used for eliminating dampness and promoting the circulation of qi, and the rhizoma atractylodis macrocephalae and the poria cocos are used as adjuvant drugs. The medicines are combined to achieve the effects of warming yang, promoting diuresis, promoting blood circulation and removing blood stasis.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine composition technology, specifically relating to a traditional Chinese medicine composition for improving frozen shoulder of the stasis-fluid type. Background Technology

[0002] Frozen shoulder due to stagnation and fluid retention is a common clinical condition characterized by shoulder pain and limited active and passive range of motion, severely impacting the quality of life for middle-aged and elderly individuals. Traditional Chinese medicine (TCM) treatment is currently the mainstream conservative approach, focusing primarily on dispelling wind and cold, promoting blood circulation, removing blood stasis, regulating qi and blood flow, and relieving pain. However, it often overlooks the "invisible edema" occurring in the shoulder joint. This edema, caused by kidney yang deficiency and impaired fluid metabolism, leads to the accumulation of dampness and fluid in the shoulder joint, hindering blood and qi circulation and causing stagnation and fluid retention, ultimately resulting in shoulder pain and limited range of motion, significantly affecting the patient's quality of life. Therefore, treatment should emphasize warming yang, promoting diuresis, and invigorating blood circulation to remove blood stasis and achieve better therapeutic effects, thereby improving the symptoms of shoulder pain and limited range of motion. Summary of the Invention

[0003] The technical problem to be solved by the present invention is to provide a traditional Chinese medicine composition for improving frozen shoulder of the type with stagnation and edema, which has the advantages of rapid symptom improvement, long duration of efficacy and few side effects. It proposes a treatment method of "warming yang and promoting diuresis, activating blood and removing blood stasis" based on the theory of "invisible edema" to treat frozen shoulder of the type with stagnation and edema.

[0004] To solve the above-mentioned technical problems, the technical solution adopted by the present invention is: a traditional Chinese medicine composition for improving frozen shoulder of the type with stagnation of blood and fluid, which is made from the following components in parts by weight: 12-18 parts of dried aconite root slices, 10-15 parts of Poria cocos, 8-10 parts of fresh ginger, 10-15 parts of Polyporus umbellatus, 16-24 parts of Alisma plantago-aquatica, 10-15 parts of prepared licorice root, 10-15 parts of dried tangerine peel, 10-15 parts of red peony root, 10-15 parts of Atractylodes macrocephala, 10-15 parts of turmeric slices, 15-20 parts of Notopterygium incisum, 10-15 parts of cinnamon twig, 15-20 parts of Astragalus membranaceus, and 10-20 parts of Clematis chinensis.

[0005] Preferably, it is made from the following components in parts by weight: 15 parts of black aconite slices, 12 parts of poria cocos, 9 parts of ginger, 12 parts of polyporus umbellatus, 20 parts of alisma plantago-aquatica, 12 parts of prepared licorice root, 12 parts of dried tangerine peel, 12 parts of red peony root, 12 parts of atractylodes macrocephala, 12 parts of turmeric slices, 18 parts of notopterygium incisum, 12 parts of cinnamon twig, 18 parts of astragalus membranaceus, and 15 parts of clematis chinensis.

[0006] Compared with the prior art, the present invention has the following advantages: 1. The traditional Chinese medicine composition of the present invention for improving frozen shoulder of the stasis-fluid type has the advantages of rapid symptom improvement, long duration of efficacy and few side effects. It treats frozen shoulder of the stasis-fluid type from the perspective of "invisible edema" and proposes the treatment method of "warming yang and promoting diuresis, activating blood and removing blood stasis".

[0007] 2. In the traditional Chinese medicine composition of this invention for improving frozen shoulder of the phlegm-dampness type, the black aconite root is a pungent, warm, and hot herb, which is good at warming and transforming dampness, promoting water metabolism, and reducing swelling. It is a "powerful medicine for opening joints" and is used as the principal ingredient. Atractylodes macrocephala dries dampness and promotes diuresis, while Poria cocos, Polyporus umbellatus, and Alisma plantago-aquatica promote diuresis and eliminate dampness. They are used as assistant ingredients for their strong diuretic effect. Cinnamomum cassia warms and unblocks the meridians, assists yang and transforms qi. Its medicinal power is good at reaching the upper limbs and shoulders, helping the black aconite root to warm and transform dampness and eliminate "invisible edema". Astragalus membranaceus tonifies qi and promotes water circulation. When qi moves, water moves. It helps Poria cocos and Atractylodes macrocephala promote diuresis and reduce swelling. Notopterygium incisum, combined with Curcuma longa and Clematis chinensis, enhances the effect of relieving pain and is especially good at treating upper limb pain. All five are assistant ingredients. Red peony root has a strong effect in promoting blood circulation, removing blood stasis, and relieving pain. When combined with prepared licorice root, it further enhances its ability to alleviate muscle spasms and pain. Fresh ginger, which is pungent and warm, is combined with prepared aconite root to enhance its warming and diuretic effects. Tangerine peel dries dampness and promotes qi circulation, which in turn promotes diuresis and assists atractylodes macrocephala and poria cocos in resolving dampness. All four herbs work together as adjuvant herbs. The combined effects of these herbs are to warm the yang, promote diuresis, and promote blood circulation to remove blood stasis.

[0008] The present invention will be further described in detail below with reference to the embodiments. Detailed Implementation

[0009] Example 1 The traditional Chinese medicine composition for improving frozen shoulder of the stasis-dampness type in this embodiment is made from the following components in parts by weight: 15 parts of black aconite root slices, 12 parts of poria cocos, 9 parts of ginger, 12 parts of polyporus umbellatus, 20 parts of alisma plantago-aquatica, 12 parts of prepared licorice root, 12 parts of tangerine peel, 12 parts of red peony root, 12 parts of atractylodes macrocephala, 12 parts of turmeric slices, 18 parts of notopterygium incisum, 12 parts of cinnamon twig, 18 parts of astragalus membranaceus, and 15 parts of clematis chinensis.

[0010] Mr. Qi, male, 50 years old, chief complaint: right shoulder joint pain for over one year; present illness: the patient reported that he developed right shoulder joint pain one year ago without any obvious cause, and sought acupuncture treatment at a local hospital without significant improvement. He is now seeking further treatment and has come for consultation. Physical examination: tenderness in the right supraspinatus and infraspinatus muscles, limited right shoulder movement, right shoulder flexion 60°, extension 20°, abduction 40°; Western medicine diagnosis: shoulder pain; Traditional Chinese medicine diagnosis: frozen shoulder; Traditional Chinese medicine syndrome type: stasis and fluid retention syndrome. He was prescribed the traditional Chinese medicine composition described in this example for improving frozen shoulder of the stasis and fluid retention type, a total of 7 doses, dosage: one dose daily, decocted in 100mL of water, taken twice daily after meals (morning and evening). The traditional Chinese medicine was combined with radial shockwave therapy for pain relief. The patient had weekly outpatient follow-up visits. After one week, the pain symptoms lessened. After three weeks of medication, the pain symptoms in the right shoulder basically disappeared. At a follow-up visit one month later, there was no obvious pain in the right shoulder joint. The range of motion of the right shoulder joint was: flexion 90°, extension 40°, and abduction 110°.

[0011] Example 2 The traditional Chinese medicine composition for improving frozen shoulder of the stasis-dampness type in this embodiment is made from the following components in parts by weight: 12 parts of black aconite, 10 parts of poria cocos, 10 parts of ginger, 10 parts of polyporus umbellatus, 24 parts of alisma plantago-aquatica, 10 parts of prepared licorice root, 10 parts of tangerine peel, 10 parts of red peony root, 15 parts of atractylodes macrocephala, 15 parts of turmeric, 20 parts of notopterygium incisum, 10 parts of cinnamon twig, 15 parts of astragalus membranaceus, and 20 parts of clematis chinensis.

[0012] Mr. Zhu, male, 51 years old, chief complaint: right shoulder joint pain for over one year; present illness: the patient reported experiencing right shoulder joint pain without any obvious cause one year ago, with more severe pain at night and intermittent attacks, and sought further diagnosis and treatment. Physical examination: tenderness in the right supraspinatus, intertubercular groove, and infraspinatus muscles; good limitation of right shoulder movement; Western medicine diagnosis: shoulder pain; Traditional Chinese medicine diagnosis: frozen shoulder; Traditional Chinese medicine syndrome type: stasis and fluid retention syndrome. He was prescribed the traditional Chinese medicine composition described in this example for improving frozen shoulder of the stasis and fluid retention type, a total of 7 doses, dosage: one dose daily, decocted in 100mL of water, taken twice daily after meals (morning and evening). The traditional Chinese medicine was combined with radial shockwave pain therapy. One week later, at the follow-up visit, the patient's right shoulder nighttime pain had disappeared, tenderness around the right shoulder was not significant, and right shoulder joint movement was good.

[0013] Example 3 The traditional Chinese medicine composition for improving frozen shoulder of the stasis-dampness type in this embodiment is made from the following components in parts by weight: 18 parts of black aconite, 15 parts of poria cocos, 8 parts of ginger, 15 parts of polyporus umbellatus, 16 parts of alisma plantago-aquatica, 15 parts of prepared licorice root, 15 parts of tangerine peel, 15 parts of red peony root, 10 parts of atractylodes macrocephala, 10 parts of turmeric, 15 parts of notopterygium incisum, 15 parts of cinnamon twig, 20 parts of astragalus membranaceus, and 10 parts of clematis chinensis.

[0014] Ms. Zhang, female, 61 years old, chief complaint: bilateral shoulder pain for more than 5 months; present illness: she reported that she began experiencing bilateral shoulder pain 5 months ago, with occasional limited joint movement, and thus came for consultation. Physical examination: significant tenderness at the attachment points of the supraspinatus tendons bilaterally, good active range of motion in both shoulder joints, and significant tenderness at the acromion bilaterally; Western medicine diagnosis: rotator cuff injury; Traditional Chinese medicine diagnosis: frozen shoulder; Traditional Chinese medicine syndrome type: stasis and fluid retention syndrome. She was prescribed the traditional Chinese medicine composition described in this example for improving frozen shoulder of the stasis and fluid retention type, a total of 10 doses, dosage: one dose daily, decocted in 100mL of water, taken twice daily after meals (morning and evening). The traditional Chinese medicine was combined with radial shockwave therapy for pain relief. Regular follow-up examinations were conducted, and she was advised to exercise, maintain a reasonable diet, pay attention to rest, and avoid heavy lifting. Weekly outpatient follow-up visits were scheduled. After 3 weeks, the shoulder pain had largely disappeared, with slight tenderness at the attachment points of the supraspinatus tendons and the acromion bilaterally remaining, and good active range of motion in both shoulder joints.

[0015] Example 4 The traditional Chinese medicine composition of this embodiment for improving frozen shoulder of the type with stasis and water retention is made from the following components in parts by weight: 16 parts of black aconite, 11 parts of poria cocos, 9 parts of ginger, 13 parts of polyporus umbellatus, 22 parts of alisma plantago-aquatica, 13 parts of prepared licorice root, 11 parts of tangerine peel, 14 parts of red peony root, 11 parts of atractylodes macrocephala, 14 parts of turmeric, 16 parts of notopterygium incisum, 11 parts of cinnamon twig, 16 parts of astragalus membranaceus, and 18 parts of clematis chinensis.

[0016] Ms. Wang, female, 52 years old, chief complaint: shoulder pain for 4 months; present illness: the patient reported that she developed shoulder pain and limited range of motion 4 months ago after exposure to cold, which was relieved by rest and was more pronounced when lying on her right side. She came for further diagnosis and treatment. Physical examination: tenderness in the shoulder joint; Western medicine diagnosis: frozen shoulder; Traditional Chinese medicine diagnosis: adhesive capsulitis; Traditional Chinese medicine syndrome type: stasis and fluid retention syndrome. She was prescribed the traditional Chinese medicine composition described in this example for improving adhesive capsulitis with stasis and fluid retention, a total of 10 doses, one dose per day, decocted in 200mL of water, taken twice daily after meals (morning and evening). Follow-up after 2 weeks showed that the patient's right shoulder pain had significantly improved, tenderness when lying on her side had disappeared, tenderness in the right shoulder joint was absent, and right shoulder joint movement was good.

[0017] Example 5 The traditional Chinese medicine composition for improving frozen shoulder of the stasis-dampness type in this embodiment is made from the following components in parts by weight: 13 parts of black aconite, 14 parts of poria cocos, 8 parts of ginger, 14 parts of polyporus umbellatus, 18 parts of alisma plantago-aquatica, 14 parts of prepared licorice root, 14 parts of tangerine peel, 11 parts of red peony root, 14 parts of atractylodes macrocephala, 11 parts of turmeric, 19 parts of notopterygium incisum, 14 parts of cinnamon twig, 19 parts of astragalus membranaceus, and 12 parts of clematis chinensis.

[0018] Mr. Wang, male, 51 years old, chief complaint: right shoulder joint pain for over one year; present illness: the patient had received three treatments for right shoulder joint pain with significant improvement, and came for a follow-up visit. Physical examination: negative tenderness around the right shoulder, limited right shoulder joint elevation; Western medicine diagnosis: shoulder pain; Traditional Chinese medicine diagnosis: frozen shoulder; Traditional Chinese medicine syndrome type: stasis and fluid retention syndrome. He was prescribed the traditional Chinese medicine composition described in this example for improving frozen shoulder of the stasis and fluid retention type, a total of 7 doses, dosage: one dose daily, decocted in 100mL of water, taken twice daily after meals (morning and evening). The traditional Chinese medicine was combined with radial shockwave therapy for pain relief. One month later, during follow-up, the patient had no significant pain in the right shoulder, negative tenderness around the right shoulder joint, and right shoulder joint elevation had basically returned to normal.

[0019] Example 6 The traditional Chinese medicine composition of this embodiment for improving frozen shoulder of the type with stasis and water retention is made from the following components in parts by weight: 17 parts of black aconite, 13 parts of poria cocos, 10 parts of ginger, 15 parts of polyporus umbellatus, 23 parts of alisma plantago-aquatica, 13 parts of prepared licorice root, 13 parts of tangerine peel, 10 to 13 parts of red peony root, 13 parts of cinnamon twig, 17 parts of astragalus membranaceus, and 16 parts of clematis chinensis.

[0020] Ms. Zhang, female, 45 years old, chief complaint: left shoulder pain for over one month; present illness: the patient reported experiencing left shoulder pain without any obvious cause one month ago, and now seeks further treatment. Physical examination: tenderness in the left supraspinatus muscle; Western medicine diagnosis: shoulder pain; Traditional Chinese medicine diagnosis: frozen shoulder; Traditional Chinese medicine syndrome type: stasis and fluid retention syndrome. She was prescribed the traditional Chinese medicine composition described in this example for improving frozen shoulder of the stasis and fluid retention type, a total of 7 doses, dosage: one dose daily, decocted in 100mL of water, taken twice daily after meals (morning and evening). The traditional Chinese medicine was combined with radial shockwave therapy for pain relief. She had weekly outpatient follow-up visits, continued medication for 3 weeks, and a follow-up visit after one month showed that the left shoulder pain was not significant, with slight discomfort when bearing weight, negative tenderness around the left shoulder joint, and good left shoulder joint mobility.

[0021] Example 7 A clinical trial was conducted to improve shoulder pain and limited range of motion caused by "invisible edema." The control group (30 cases) received simple extracorporeal shock wave therapy, while the experimental group (30 cases) received a combination of the traditional Chinese medicine composition of this invention for improving edema-related frozen shoulder with extracorporeal shock wave therapy. Scores were compiled showing significant therapeutic effects. Specifically: 1. Clinical efficacy period: 1-2 weeks 2. Comparison of clinical trial scores (1) Comparison of VAS scores before and after treatment in the two groups of patients Table 1 Comparison of VAS scores before and after treatment in the two groups of patients As shown in Table 1, the VAS scores of the two groups before and after treatment were statistically significant (P=0.012<0.05).

[0022] (2) Comparison of CMS scores before and after treatment between the two groups of patients Table 2 Comparison of CMS scores before and after treatment in the two groups of patients As shown in Table 2, the comparison of CMS scores between the two groups before and after treatment showed that P=0.027<0.05, indicating a statistically significant difference.

[0023] (3) Comparison of ADL scores before and after treatment between the two groups of patients Table 3 Comparison of ADL scores before and after treatment in the two groups of patients As shown in Table 3, the comparison of ADL scores between the two groups before and after treatment showed that P=0.043<0.05, indicating a statistically significant difference.

[0024] The traditional Chinese medicine composition of the present invention for improving frozen shoulder of the stasis-fluid type has the advantages of long duration of efficacy and few side effects. It treats frozen shoulder of the stasis-fluid type from the perspective of "invisible edema" and proposes a treatment method of "warming yang and promoting diuresis, activating blood and removing blood stasis".

[0025] In this invention, the traditional Chinese medicine composition for improving frozen shoulder of the phlegm-dampness type comprises black aconite root, which is pungent, warm, and extremely hot in nature. It is good at warming and transforming dampness, promoting water metabolism, and relieving swelling. It is a "powerful medicine for opening joints" and is used as the principal ingredient. Atractylodes macrocephala dries dampness and promotes diuresis, while Poria cocos, Polyporus umbellatus, and Alisma plantago-aquatica promote diuresis and eliminate dampness. They are used as assistant ingredients due to their strong diuretic effect. Cinnamomum cassia warms and unblocks the meridians, assists yang and transforms qi. Its medicinal power is good at reaching the upper limbs and shoulders, helping black aconite root to warm and transform dampness and eliminate "invisible edema". Astragalus membranaceus tonifies qi and promotes water circulation. When qi moves, water moves. It helps Poria cocos and Atractylodes macrocephala promote diuresis and reduce swelling. Notopterygium incisum, combined with Curcuma longa and Clematis chinensis, enhances the effect of relieving pain and is especially good at treating upper limb pain. All five ingredients are used as assistant ingredients. Red peony root has a strong effect in promoting blood circulation, removing blood stasis, and relieving pain. When combined with prepared licorice root, it further enhances its ability to alleviate muscle spasms and pain. Fresh ginger, which is pungent and warm, is combined with prepared aconite root to enhance its warming and diuretic effects. Tangerine peel dries dampness and promotes qi circulation, which in turn promotes diuresis and assists atractylodes macrocephala and poria cocos in resolving dampness. All four herbs work together as adjuvant herbs. The combined effects of these herbs are to warm the yang, promote diuresis, and promote blood circulation to remove blood stasis.

[0026] The above description is merely a preferred embodiment of the present invention and is not intended to limit the invention in any way. Any simple modifications, alterations, and equivalent changes made to the above embodiments based on the inventive essence shall still fall within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition for improving frozen shoulder of the stasis-fluid type, characterized in that, It is made from the following components in parts by weight: 12-18 parts of dried aconite root slices, 10-15 parts of Poria cocos, 8-10 parts of fresh ginger, 10-15 parts of Polyporus umbellatus, 16-24 parts of Alisma plantago-aquatica, 10-15 parts of prepared licorice root, 10-15 parts of dried tangerine peel, 10-15 parts of red peony root, 10-15 parts of Atractylodes macrocephala, 10-15 parts of turmeric slices, 15-20 parts of Notopterygium incisum, 10-15 parts of cinnamon twig, 15-20 parts of Astragalus membranaceus, and 10-20 parts of Clematis chinensis.

2. The traditional Chinese medicine composition for improving frozen shoulder of the stasis-dampness type according to claim 1, characterized in that, It is made from the following components in parts by weight: 15 parts of black aconite, 12 parts of poria cocos, 9 parts of ginger, 12 parts of polyporus umbellatus, 20 parts of alisma plantago-aquatica, 12 parts of prepared licorice root, 12 parts of dried tangerine peel, 12 parts of red peony root, 12 parts of atractylodes macrocephala, 12 parts of turmeric slices, 18 parts of notopterygium incisum, 12 parts of cinnamon twig, 18 parts of astragalus membranaceus, and 15 parts of clematis chinensis.

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