Golden triangle support anti-aging method

Abstract

The invention discloses a golden triangular support anti-aging method. The method comprises the following steps: S1, barrier pretreatment; S2, active component delivery; S3, photocuring network shaping; according to the golden triangle support anti-aging method, synthesis and degradation balance of three core components of a skin extracellular matrix are synergistically regulated and controlled, and a golden triangle support system is formed. The small molecule peptide Pro-Hyp-Gly in the collagen activation component and the copper ion chelate act together, so that fibroblasts are promoted to secrete collagen, and the skin supporting force is enhanced; beta-aminopropionitrile serving as a lysyl oxidase inhibitor in the elastin protection component and vitamin E succinate have a synergistic effect, so that the degradation of elastin is inhibited, and the skin elasticity is maintained; the hyaluronic acid synergistic component is compounded by hyaluronic acid with different molecular weights to form a graded water locking network, so that the water content and plumpness of the skin are improved.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of anti-aging technology, in particular to a golden triangle support anti-aging method. BACKGROUND

[0002] With the continuous progress of anti-aging skin care technology, consumers have higher requirements for the efficacy and use experience of anti-aging products. At present, most of the anti-aging products on the market realize multiple effects such as anti-wrinkle, moisturizing, repair, etc. through the compounding of active ingredients. However, the existing technical solutions still have certain deficiencies in terms of ingredient synergy, absorption efficiency and use comfort, which limits the maximum exertion of their anti-aging effect.

[0003] After searching, a kind of anti-aging composition and its preparation method and application, anti-aging skin care product with publication number CN114617792B are disclosed, and the publication date is November 18, 2022. The patent discloses that by synergistic effect of hydroxyl asiatic acid, enzyme cut sodium hyaluronate and β-alanyl hydroxyproline diamino butyric acid benzylamine in a specific ratio, collagen and elastin are effectively protected and supplemented, so as to improve skin elasticity and dermal layer thickness. However, the mechanism of action of each active ingredient in this technical solution is relatively single, mainly focusing on the protection and supplementation of collagen and elastin, lacking overall consideration of the multi-level support structure of the skin, which may lead to insufficient comprehensive anti-aging effect. In addition, the composition does not involve technical means to promote the deep penetration of active ingredients, which may affect its absorption efficiency and long-term effect in the skin.

[0004] After searching, a kind of anti-wrinkle anti-aging essence and its preparation method with publication number CN110755325B are disclosed, and the publication date is February 12, 2021. The patent realizes the nourishment and anti-wrinkle anti-aging effect on the skin through the effective compounding of resurrection grass extract, radix saposhnikoviae extract and lycium barbarum peptide. Although this technical solution focuses on extracting active ingredients from plants to safely improve skin condition, its mechanism of action mainly focuses on antioxidant and cell nourishment level, failing to fully consider the stereoscopic support needs of skin structure. In addition, the formula system of the essence may have certain limitations in applicability on different skin types, and the delivery system of active ingredients is not optimized, which may lead to insufficient stability and durability of anti-aging effect.

[0005] The above problems show that the existing anti-aging technical solutions still have certain deficiencies in terms of ingredient synergy, construction of multi-level support structure of the skin, and delivery and absorption of active ingredients. Therefore, the present application provides a golden triangle support anti-aging method, which aims to comprehensively improve the support, elasticity and anti-aging effect of the skin through multi-level, multi-dimensional synergistic effect of active ingredients, combined with efficient delivery technology, while optimizing the use experience to meet the needs of consumers for high-efficiency anti-aging products. SUMMARY

[0006] The purpose of this invention is to provide a golden triangle support anti-aging method to solve the problems of existing anti-aging compositions mentioned in the background art.

[0007] To achieve the above objectives, the present invention provides the following technical solution:

[0008] A golden triangle support anti-aging method includes the following steps:

[0009] S1. Barrier Pretreatment: Massage the face with a pH 5.5 amino acid facial cleanser for 60 seconds and rinse with 35°C warm water; use a diamond abrasive head with a particle size of 100 microns to move unidirectionally along the skin texture to cover the forehead, nose, cheeks and jaw area, repeating three times for each area, with an operating pressure of 0.2 MPa and a moving speed of 2 cm per second; spray with physiological saline containing 2% panthenol at 4°C, spraying at a distance of 20 cm for 10 seconds, with an atomized particle size of 50 microns; apply a 0.5 mm thick hydrogel film of 5% glycerin and 1% menthol for 10 minutes.

[0010] S2. Delivery of active ingredients: Prepare collagen activating solution, elasticity protecting solution and hyaluronic acid enhancing solution, mix them in a ratio of 1:0.4:0.5 (collagen activating solution to elasticity protecting solution to hyaluronic acid enhancing solution) and inject them into the instrument, such as the seven-dimensional beauty instrument, to penetrate the mixture into the skin tissue.

[0011] S3. Photocurable network shaping: Apply 0.1% riboflavin hydrogel evenly to the entire face, with an application amount of 0.05 grams per square centimeter; use an LED mask with a wavelength of 415 nanometers for irradiation, 15 centimeters away from the skin, with a light intensity of 40 milliwatts per square centimeter, for 10 minutes; switch to red light with a wavelength of 630 nanometers for irradiation for 5 minutes, with a light intensity of 20 milliwatts per square centimeter.

[0012] S4. Home Care: In the morning, after cleansing, apply a slow-release cream containing 0.5% active ingredient liposomes, and use a handheld red light device with a wavelength of 630 nanometers to irradiate the entire face for 10 minutes at a distance of 10 centimeters; in the nighttime, use a 0.5 mA microcurrent infusion device to assist in the penetration of a home-use serum containing 0.3% active ingredient.

[0013] Preferably, the type and concentration of surfactant in the amino acid facial cleanser described in S1 must ensure that the skin barrier function is not damaged during the cleansing process.

[0014] Preferably, the collagen activating solution in S2 consists of 1.0% Pro-Hyp-Gly, 0.05% copper peptide, and buffer solution;

[0015] The elastic protective fluid described in S2 consists of 0.3% β-aminopropionitrile, 0.5% vitamin E succinate, 5% ethanol, and deionized water.

[0016] Preferably, the delivery of the active ingredient in S2 requires understanding the connection relationship between the 44 muscles of the face, obtaining triangular support, and then using an instrument to penetrate the mixture into the skin tissue.

[0017] Preferably, the hyaluronic acid enhancing solution in S2 is composed of 0.3% hyaluronic acid with a molecular weight of 50,000 Daltons, 0.1% hyaluronic acid with a molecular weight of 1 million Daltons, and deionized water.

[0018] Preferably, the blue light irradiation in S3 is achieved through an LED mask with a wavelength of 415 nanometers, a light intensity of 40 milliwatts per square centimeter, and a duration of 10 minutes.

[0019] Preferably, the red light irradiation in S3 is achieved through an LED mask with a wavelength of 630 nanometers, a light intensity of 20 milliwatts per square centimeter, and a duration of five minutes.

[0020] Preferably, the sustained-release cream in S4 contains 0.5% liposomes of active ingredients, and the active ingredients are the golden triangle active ingredients.

[0021] Preferably, the home-use essence described in S4 contains 0.3% active ingredients, and the active ingredients are the golden triangle active ingredients.

[0022] A formulation comprising a temperature-sensitive poloxamer 407 gel as a carrier, containing 0.5% to 2% nanoliposomes encapsulating the active ingredient.

[0023] Compared with existing technologies, the beneficial effects of this invention are as follows: This "golden triangle" support anti-aging method forms a "golden triangle" support system by synergistically regulating the synthesis and degradation balance of the three core components of the skin's extracellular matrix. The small molecule peptide Pro-Hyp-Gly in the collagen activating component works synergistically with copper ion chelates to promote collagen secretion by fibroblasts, enhancing skin support. The lysyl oxidase inhibitor β-aminopropionitrile in the elastin protecting component works synergistically with vitamin E succinate to inhibit elastin degradation and maintain skin elasticity. The hyaluronic acid synergistic component, through the combination of hyaluronic acid of different molecular weights, forms a hierarchical water-locking network, increasing skin hydration and plumpness. The synergistic effect between the components not only achieves comprehensive construction of a multi-layered support structure for the skin but also significantly improves the stability and durability of the anti-aging effect.

[0024] By using a barrier pretreatment step, the permeability of active ingredients is effectively improved, solving the problem that active ingredients are difficult to penetrate deep into the skin in existing technologies.

[0025] The innovative combination of microneedle puncture, ultrasonic infusion, and iontophoresis significantly improves the delivery efficiency of active ingredients.

[0026] The photocuring network shaping step enhances the stability and mechanical properties of the skin support structure through the synergistic effect of blue and red light;

[0027] The home maintenance program further enhances the long-lasting anti-aging effect by using a slow-release cream in combination with a microcurrent infusion device.

[0028] The formulation design utilizes poloxamer 407 gel and nanoliposome encapsulation technology to ensure the stability and controlled release of active ingredients, meeting the needs of different skin types. Detailed Implementation

[0029] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0030] The present invention provides a technical solution: a golden triangle support anti-aging method, wherein in the barrier pretreatment step, a pH 5.5 amino acid facial cleanser is first used for cleaning.

[0031] The formulation of facial cleansers must strictly control the types and concentrations of surfactants to ensure that the skin barrier function is not damaged during the cleansing process.

[0032] The specific procedure is as follows: Apply an appropriate amount of facial cleanser evenly to the face, massage in circular motions along the skin texture for 1 minute, and then rinse thoroughly with lukewarm water at 35±2℃. This temperature range is selected based on experimental data on human skin tolerance and the stability of the stratum corneum barrier, to avoid damage to the skin barrier due to excessively high or low water temperatures.

[0033] Next comes the microdermabrasion step, using a diamond abrasive head with a 100μm abrasive particle size. Diamond was chosen for its moderate hardness and high surface smoothness, effectively removing dead skin cells without damaging new cells. During the procedure, the abrasive head should be moved unidirectionally along the skin texture, covering the forehead, nose, cheeks, and jawline in sequence, repeating three times for each area.

[0034] During operation, the pressure is controlled at 0.2 MPa and the moving speed is 2 cm / s. These two parameters have been verified through multiple experiments and can minimize mechanical irritation to the skin while ensuring effectiveness.

[0035] The cold spray sedation step involved spraying a 4°C saline solution containing 2% panthenol at a fixed distance of 20 cm for 10 seconds, with a particle size of 50 μm. This step alleviated the irritation caused by abrasion through the synergistic effect of low temperature and panthenol, which constricted blood vessels and reduced the release of the inflammatory factor IL-1β. Finally, in the penetration enhancement step, a 0.5 mm thick 5% glycerol + 1% menthol hydrogel membrane was applied for 10 minutes. Electron microscopy confirmed that this step expanded the lipid bilayer gap to 50 nm, further improving the penetration efficiency of subsequent active ingredients.

[0036] The active component delivery step is the core of this method, which first requires the preparation of three liquid components and their mixing in specific proportions. The collagen activating solution consists of Pro-Hyp-Gly 1.0%, copper peptide (GHK-Cu) 0.05%, and buffer (pH 6.8). The elasticity protection solution includes β-aminopropionitrile 0.3%, vitamin E succinate 0.5%, and ethanol 5%. The hyaluronic acid enhancing solution consists of 50kDa hyaluronic acid 0.3%, 1MDa hyaluronic acid 0.1%, and deionized water.

[0037] The mixing ratio of the three components is collagen activating solution: elasticity protecting solution: hyaluronic acid enhancing solution = 1:0.4:0.5. The mixing process must be completed in a dual-channel mixing syringe with an oscillation frequency of 120 rpm and a duration of 30 seconds to ensure that each component is fully and evenly mixed.

[0038] Specifically, first understand the connections between the 44 facial muscles. For example, the frontalis, brow, and shin muscles form a triangle, which constitutes triangular support. Then, using an instrument, such as a seven-dimensional beauty device, a mixed solution is penetrated into the skin tissue. Through targeted thermal effects, the tissue is loosened, the fascia is relaxed, the muscles regain elasticity, and the vitality of the muscles is increased, thereby achieving the effect of triangular support and further improving muscle stability. This method can also be used for muscles throughout the body. By determining the triangular connections between muscles throughout the body, the stability of muscles throughout the body can be improved.

[0039] The 7D beauty device uses sound wave targeting and thermal energy principles to evenly and stably apply the product to muscles. It also uses the penetrability of sound waves to precisely and layer the mixed solution into the skin tissue, and utilizes the persistence of sound waves to reach the muscle layer like radar, resulting in long-lasting effects.

[0040] The photocuring network setting process consists of three parts: photosensitizer coating, blue light irradiation, and red light stabilization. First, a 0.1% riboflavin (vitamin B2) hydrogel is evenly applied to the entire face at a concentration of 0.05 g / cm³. 2As a crosslinking medium. Blue light irradiation was performed using an LED mask with a wavelength of 415±5nm, at a distance of 15cm from the skin, and a light intensity of 40mW / cm². 2 The duration was 10 minutes. Blue light activated riboflavin to produce reactive oxygen species (ROS), inducing the formation of cross-linked networks in collagen and elastin fibers. The red light stabilization step involved switching to 630nm red light irradiation for 5 minutes at an intensity of 20mW / cm². 2 This is used to suppress potential oxidative damage from blue light. This step strengthens and stabilizes the skin's supporting structures through the alternating use of two light sources.

[0041] The home care routine consists of two parts: morning and nighttime skincare. The morning skincare involves applying a slow-release cream after cleansing. This cream contains 0.5% liposomes of the Golden Triangle active ingredient. Then, a handheld red light therapy device (630nm) is used to irradiate the entire face for 10 minutes at a distance of 10cm. The nighttime skincare uses a microcurrent infusion device (0.5mA) to aid in the penetration of a home-use serum containing 0.3% active ingredients. This step consolidates the long-lasting anti-aging effects through daily skincare.

[0042] This invention also discloses a formulation using the above method, wherein the carrier is a temperature-sensitive poloxamer 407 gel containing 0.5%-2% nanoliposomes encapsulating the active ingredient. This formulation protects the active ingredient from external environmental interference through liposome encapsulation technology, while utilizing the temperature-sensitive properties of the poloxamer 407 gel to achieve slow release and prolong the duration of action.

[0043] Mixing tolerance experimental data

[0044]

[0045] Device Parameter Safety Window

[0046]

[0047] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A golden triangle support method for anti-aging, characterized in that: Includes the following steps: S1. Barrier Pretreatment: Massage the face with a pH 5.5 amino acid facial cleanser for 60 seconds and rinse with 35°C warm water; use a diamond abrasive head with a particle size of 100μm to cover the forehead, nose, cheeks and jaw area in one direction along the skin texture, repeating three times for each area, with an operating pressure of 0.2MPa and a moving speed of 2cm / s; spray with physiological saline containing 2% panthenol at 4°C, spraying at a distance of 20cm for 10 seconds, with an atomized particle size of 50μm; apply a 0.5mm thick 5% glycerin plus 1% menthol hydrogel film for 10 minutes; S2. Delivery of active ingredients: Prepare collagen activating solution, elastic protective solution and hyaluronic acid enhancing solution, mix them in a ratio of collagen activating solution to elastic protective solution to hyaluronic acid enhancing solution of 1:0.4:0.5 and inject them into the instrument, such as the seven-dimensional beauty instrument, to penetrate the mixture into the skin tissue; S3. Photocurable network shaping: Apply 0.1% riboflavin hydrogel evenly to the entire face, with an application amount of 0.05 grams per square centimeter; use an LED mask with a wavelength of 415 nanometers for irradiation, 15 centimeters away from the skin, with a light intensity of 40 milliwatts per square centimeter, for 10 minutes; switch to red light with a wavelength of 630 nanometers for irradiation for 5 minutes, with a light intensity of 20 milliwatts per square centimeter. S4. Home Care: In the morning, after cleansing, apply a slow-release cream containing 0.5% active ingredient liposomes, and use a handheld red light device with a wavelength of 630 nanometers to irradiate the entire face for 10 minutes at a distance of 10 centimeters; in the nighttime, use a 0.5 mA microcurrent infusion device to assist in the penetration of a home-use serum containing 0.3% active ingredient.

2. The anti-aging method based on the golden triangle support according to claim 1, characterized in that: The type and concentration of surfactants in the amino acid facial cleanser described in S1 must ensure that the skin barrier function is not damaged during the cleansing process.

3. The anti-aging method based on the golden triangle support according to claim 1, characterized in that: The collagen activating solution described in S2 consists of 1.0% Pro-Hyp-Gly, 0.05% copper peptide, and buffer solution.

4. The anti-aging method based on the golden triangle support according to claim 1, characterized in that: The elastic protective fluid in S2 is composed of 0.3% β-aminopropionitrile, 0.5% vitamin E succinate, 5% ethanol and deionized water. The hyaluronic acid enhancing solution described in S2 consists of 0.3% hyaluronic acid with a molecular weight of 50,000 Daltons, 0.1% hyaluronic acid with a molecular weight of 1 million Daltons, and deionized water.

5. The anti-aging method based on the golden triangle support according to claim 1, characterized in that: The delivery of the active ingredients described in S2 requires understanding the connection relationship between the 44 muscles of the face, obtaining triangular support, and then using an instrument to penetrate the mixture into the skin tissue.

6. The anti-aging method based on the golden triangle support according to claim 1, characterized in that: The blue light irradiation described in S3 is achieved through an LED mask, with a wavelength of 415 nanometers, a light intensity of 40 milliwatts per square centimeter, and a duration of ten minutes.

7. The anti-aging method using the golden triangle support according to claim 1, characterized in that, The red light irradiation described in S3 is achieved through an LED mask with a wavelength of 630 nanometers, a light intensity of 20 milliwatts per square centimeter, and a duration of five minutes.

8. The anti-aging method based on the golden triangle support according to claim 1, characterized in that: The sustained-release cream described in S4 contains 0.5% liposomes of active ingredients, and the active ingredients are the golden triangle active ingredients.

9. The anti-aging method based on the golden triangle support according to claim 1, characterized in that: The home-use essence described in S4 contains 0.3% active ingredients, and the active ingredients are the golden triangle active ingredients.

10. A formulation using the method according to any one of claims 1 to 9, characterized in that... The carrier is a temperature-sensitive poloxamer 407 gel containing 0.5% to 2% nanoliposomes encapsulating the active ingredient.

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