Medicinal moxa stick for treating cold-dampness arthralgia type shoulder numbness

Abstract

The invention belongs to the technical field of medicinal moxa sticks, and particularly relates to a medicinal moxa stick for treating cold-dampness arthralgia type shoulder arthralgia, the medicinal moxa stick comprises the following raw materials by weight: 70-80 parts of moxa, 2-5 parts of giantleaf ardisia rhizome, 1-5 parts of frankincense, 3-8 parts of processed monkshood, 1-5 parts of dried ginger, 1-5 parts of beautiful sweetgum fruit, 5-10 parts of tinospora sinensis merr, 1-5 parts of spatholobus stem, 1-5 parts of bark of himalayan coralbean and 5-10 parts of pogostemon cablin. The medicinal moxa stick is obtained through a multi-target synergistic formula, controllable toxic components, smell and smoke optimization and the like, and compared with an existing medicinal moxa stick, the curative effect is remarkably improved; the safety is high, the toxicity is controllable, and skin irritation and anaphylactic reaction are avoided; the smoke is less, the smell is pleasant, and the use experience effect is good.

Description

Technical Field

[0001] This invention relates to the field of moxa stick technology, specifically to a moxa stick for treating shoulder pain caused by cold and dampness. Background Technology

[0002] Medicated moxa sticks are a traditional Chinese medicine material used in moxibustion. They are made by rolling a mixture of moxa wool and specific Chinese herbal powders, combining the effects of moxibustion and medication. They are commonly used to warm the meridians, dispel cold, and promote blood circulation. They are suitable for conditions such as wind-cold-dampness syndrome and dysmenorrhea due to uterine cold. However, proper use is necessary to avoid the risk of burns or allergic reactions.

[0003] Traditional pure moxa sticks contain only moxa wool, offering a limited warming and invigorating effect. They are insufficiently targeted at cold-dampness obstruction and lack the synergistic effect of other dampness-removing and blood-activating medications. Furthermore, the smoke from burning traditional pure moxa sticks is highly irritating, has a monotonous aroma, and results in low patient compliance.

[0004] Most existing moxa sticks use simple compound formulas (such as moxa wool + 12 herbs), lacking a systematic approach to drug compatibility and failing to achieve the synergistic effects of warming, unblocking, activating, and dissolving. The proportions or processing methods of toxic herbs (such as aconite) are not controlled, posing safety hazards. They also suffer from poor combustion stability (easily scattering, producing dense smoke) and lack any ingredients designed to improve odor. Summary of the Invention

[0005] To address the aforementioned problems, this invention provides a medicated moxa stick for treating shoulder pain caused by cold and dampness. This medicated moxa stick is obtained through multi-target synergistic formulation, controllable toxicity components, and optimized odor and smoke. Compared with existing medicated moxa sticks, it has significantly improved efficacy, high safety, controllable toxicity, no skin irritation or allergic reactions, and advantages such as less smoke, pleasant odor, and excellent user experience.

[0006] The present invention adopts the following technical solution:

[0007] A medicated moxa stick for treating shoulder pain due to cold-dampness obstruction, the medicated moxa stick comprising the following raw materials in parts by weight: 70-80 parts of moxa wool, 2-5 parts of *Lysimachia christinae*, 1-5 parts of frankincense, 3-8 parts of processed aconite root, 1-5 parts of dried ginger, 1-5 parts of *Ligusticum striatum*, 5-10 parts of *Tinospora sinensis*, 1-5 parts of *Spatholobus suberectus*, 1-5 parts of *Erythrina variegata* bark, and 5-10 parts of patchouli.

[0008] Preferably, the moxa stick comprises the following raw materials in parts by weight: 75 parts of moxa wool, 3 parts of horsehair flakes, 3 parts of frankincense, 5 parts of processed aconite root, 3 parts of dried ginger, 3 parts of *Luffa cylindrica*, 8 parts of *Tinospora sinensis*, 3 parts of *Spatholobus suberectus*, 3 parts of *Erythrina variegata* bark, and 6 parts of patchouli.

[0009] Preferably, the processed Aconitum carmichaelii is a product dried after soaking in 10% licorice water, and the aconitine residue is ≤0.02%.

[0010] Preferably, honey water is added as a binder during the preparation of the moxa stick.

[0011] Preferably, the method for preparing the moxa stick is as follows:

[0012] (1) Slice the prepared Aconitum carmichaelii, soak it in licorice water for 2 hours to obtain processed Aconitum carmichaelii, and dry it for later use.

[0013] (2) Grind the following ingredients into powder: horse antler powder, frankincense, processed aconite root, dried ginger, luffa cylindrica, kuanjin vine, chicken blood vine, erythrina bark, and patchouli. Sift them to obtain the powders of each ingredient.

[0014] (3) Weigh out each medicine powder according to the above weight proportions, mix them, add the adhesive honey water, and stir evenly;

[0015] (4) Moxa stick forming: Mix the well-stirred medicinal powder and moxa wool at a ratio of 1:3, and roll the mixture into a tight moxa stick with a diameter of 1.5cm and a length of 20cm.

[0016] Preferably, the sieving is performed through a 100-mesh sieve.

[0017] Preferably, the honey water is 5% honey water.

[0018] Preferably, the density of the moxa stick is greater than or equal to 0.8 g / cm³. 3 .

[0019] The drug compatibility effect in this invention is analyzed in a stratified manner as follows:

[0020] (I) Principal Herb Group: Warming Yang and Dispelling Cold, Directly Targeting the Root Cause of the Disease

[0021] 1. Artemisia floss (pungent, bitter, warm; enters the liver, spleen, and kidney meridians)

[0022] Its effect of dispelling cold: The "pure yang" power of moxa penetrates into the muscles and bones, melting away the cold. The "Compendium of Materia Medica" states that it "unblocks the twelve meridians, traverses the three yin meridians, expels cold and dampness, and warms the uterus." The volatile components such as eucalyptol and thujone released during combustion can dilate local capillaries and accelerate the dissipation of cold pathogens.

[0023] The profound meaning of the combination: It serves as the "boat and oars" for all medicines, using the heat of moxibustion to bring the medicinal properties into the deep tissues; it forms a "Taiyang (moxa) Taiyin (ginger)" correspondence with dried ginger, warming and unblocking the Qi mechanism of the three Jiaos (exterior and interior).

[0024] 2. Prepared Aconitum carmichaelii (pungent, bitter, and hot; enters the heart, liver, and kidney meridians)

[0025] Its warming properties allow it to penetrate deep into the muscles and bones. The Shennong's Classic of Materia Medica states that it "removes cold and dampness, and breaks up accumulations of pathogenic factors." The aconitine it contains (in trace amounts after processing) can inhibit the transmission of local pain nerves and quickly relieve cold pain.

[0026] Deep meaning of compatibility: Compatibility with honey (adhesive) can relieve toxicity, with the meaning of "sweetness relieving harshness"; it forms the prescription structure of "Aconite and Dry Ginger" (although it is not aconite, but based on the principle of mutual reinforcement of pungency and heat of ginger and aconite), enhancing the effect of expelling cold.

[0027] (2) Ministerial drug group: Promote blood circulation to dredge collaterals, resolve dampness and relieve pain

[0028] 1. Frankincense (pungent, bitter, warm; attributing to the heart, liver, and spleen meridians)

[0029] Effect of removing blood stasis: Boswellic acid, a resin component in frankincense, can inhibit cyclooxygenase (COX2), reducing the generation of local inflammatory mediators (such as PGE2); the pungent and fragrant property promotes qi and blood circulation, breaking the blood stasis caused by "blood coagulating when encountering cold". It is stated in "Medical Compendium of Chinese and Western Medicine" that: "Frankincense promotes qi, myrrh disperses blood".

[0030] Deep meaning of compatibility: It forms a dynamic balance of "promoting blood circulation and nourishing blood" with Caulis Spatholobi, preventing excessive blood circulation from damaging healthy qi; its fat-soluble components are more easily absorbed through the skin under the heating of moxa, enhancing the local analgesic effect.

[0031] 2. Dry Ginger (pungent, hot; attributing to the spleen, stomach, heart, and lung meridians)

[0032] Effect of dispelling cold: Warming the middle jiao to strengthen the "source of qi and blood generation". In "Treatise on Febrile Diseases", "Decoction of Dry Ginger and Aconite" takes this effect of warming the interior and dispelling cold; gingerol can stimulate blood flow on the body surface, and together with moxa wool, expel cold pathogens on the surface of the shoulder.

[0033] Deep meaning of compatibility: It forms a "coordination of moving and guarding" with Radix Aconiti: Radix Aconiti moves and expels deep cold, Dry Ginger guards the middle and warms yang qi; warming and promoting the spleen yang to cut off the source of damp pathogen generation, conforming to the theory that "the spleen is the viscera that generates dampness".

[0034] 3. Ardisia gigantifolia: pungent, warm; attributing to the liver and kidney meridians, expelling wind and promoting blood circulation, strengthening muscles and bones, dissipating stasis and detumescence, warming and dredging collaterals, improving cold-damp obstruction. Warming and dispersing cold pathogens, strengthening muscles and bones, synergistically enhancing the warming and dredging effect with Radix Aconiti and Dry Ginger.

[0035] (3) Assistant drug group: Resolve dampness and relax tendons, regulate yin and yang

[0036] 1. Liquidambar formosana Hance (bitter, flat; attributing to the liver and kidney meridians)

[0037] Effect of resolving dampness: Hollow like a network, promoting the flow of qi in the triple energizer and water passages. It is recorded in "Supplementary Records of Compendium of Materia Medica" that: "It can flow through the twelve meridians and treat edema and fullness"; the contained liquidambaric acid can promote lymphatic return and accelerate the metabolism of damp pathogens.

[0038] Deep meaning of compatibility: It forms a drug pair of "dredging collaterals and resolving dampness" with Pittosporum tobira: Liquidambar formosana Hance dredges meridians and promotes diuresis, Pittosporum tobira dispels wind and dries dampness; its flat nature regulates the dryness and heat of moxa and aconite, preventing damage to body fluids and transformation into fire.

[0039] 2. Tinospora sinensis (Lour.) Merr. (slightly bitter, cool; attributing to the liver meridian)

[0040] Its muscle-relieving properties: Its cooling and moisturizing nature can relieve muscle spasms caused by cold and dampness. The "Lingnan Herbal Collection" states that it "specifically treats muscle contracture and spasms". The alkaloid it contains can inhibit muscle spasm-related receptors (such as NMDA receptors).

[0041] The profound meaning of the combination: It counteracts the warm and dry nature of the whole formula, which is in line with the principle of "treating cold without going too far with warmth, and adding cooling and moisturizing to prevent excess"; it works with chicken blood vine to treat "tendon diseases": chicken blood vine nourishes blood and tendons, while wide tendon vine relaxes tendons and activates blood circulation.

[0042] 3. Erythrina bark (bitter, pungent, neutral; enters the liver and spleen meridians)

[0043] Its dampness-removing effect is pungent and bitter, reaching directly into the joint cavities to expel wind and dampness. The Kaibao Materia Medica states that it "treats weakness of the waist and legs, stubborn numbness, and pain in the legs and knees." The erythritol it contains can inhibit synovial inflammation and reduce joint swelling.

[0044] Profound meaning of the combination: Together with the tamarind root, it dispels the evil of "rheumatism": the tamarind root dispels wind and invigorates blood, while the erythrina bark dispels dampness and unblocks the meridians; its characteristic of entering the spleen meridian helps the dried ginger to transform dampness and turbidity in the middle jiao.

[0045] (iv) Guiding herbs: dispel turbidity and harmonize the effects of other herbs.

[0046] 1. Chicken Blood Vine (bitter, sweet, warm; enters the liver and kidney meridians)

[0047] Blood-nourishing effects: It replenishes liver blood to moisten tendons and veins. The Compendium of Materia Medica states that it "invigorates blood circulation, relaxes tendons and muscles, and treats numbness in the hands and feet." Chicken blood vine flavonoids can promote bone marrow hematopoiesis and improve local blood deficiency caused by cold and dampness obstruction.

[0048] Profound meaning of the combination: It enters the liver and kidney meridians, guiding the medicine into the tendons and bones, which is in line with the theory that "the liver governs the tendons and the kidneys govern the bones"; its sweet and warm nature harmonizes the pungent and strong flavors of Aconitum carmichaelii and Frankincense, reflecting the idea of ​​"pungent and sweet transforming into yang" in the combination.

[0049] 2. Patchouli (pungent, slightly warm; enters the spleen, stomach, and lung meridians)

[0050] Its function of clearing away turbidity is to invigorate the spleen with its fragrance and dispel the foul odor of mugwort smoke. The "Compendium of Materia Medica" states that it is "fragrant but not overpowering, and warm but not excessively hot." Patchouli can inhibit respiratory inflammation and reduce the irritation of smoke.

[0051] Profound meaning of the combination: As a "guide and messenger", its characteristic of entering the spleen and stomach meridians guides the medicinal power to be distributed in the muscles (the spleen governs the muscles); together with dried ginger, it treats the "source of dampness": dried ginger warms the spleen yang to eliminate dampness, and patchouli transforms dampness and turbidity to dispel evil.

[0052] The compatibility characteristics of the drugs in this invention are as follows:

[0053] 1. Dissipation of Cold and Dampness:

[0054] Dispelling cold: Mugwort floss, aconite root, and dried ginger form a "thermal triangle" to melt away the cold stagnation in the shoulders;

[0055] To dispel dampness: The combination of Liquidambar formosana, Erythrina variegata bark, and Patchouli forms a "three-jiao dampness-dispelling network" (upper jiao promotes lung function, middle jiao strengthens spleen function, and lower jiao promotes diuresis).

[0056] 2. A balance of strength and gentleness:

[0057] The main ingredients are Aconitum carmichaelii and Boswellia carterii, which are pungent and volatile, and can dispel cold and remove blood stasis.

[0058] Gentle herbs: Chicken blood vine and broad vine are sweet, moist and mild, preventing dryness and damage to yin.

[0059] 3. Odor therapy:

[0060] Artemisia leaves are bitter and pungent, frankincense is resinous and fragrant, and patchouli is refreshing. When burned, they form a complex aromatic scent, which is in line with the transdermal drug delivery concept in "Li Yue Pian Wen" that "the principle of external treatment is the same as the principle of internal treatment, and the medicine for external treatment is the same as the medicine for internal treatment. The only difference is the method."

[0061] This formula closely addresses the four pathological aspects of "cold, dampness, blood stasis, and spasm," adhering to the treatment principle of "treating cold with heat" from the Yellow Emperor's Inner Classic, while also incorporating modern transdermal absorption and component pharmacology, achieving a deep integration of traditional theory and modern technology.

[0062] Based on the detailed explanation of the drug compatibility effects and characteristics above, it can be seen that the drug of this invention closely follows the pathogenesis of cold-dampness obstruction and is suitable for the treatment of cold-dampness obstruction.

[0063] By adopting the above technical solution, the present invention has at least the following beneficial effects:

[0064] 1. In terms of drug compatibility, this invention employs a multi-target synergistic formulation design, using mugwort floss as a carrier, combined with buergerianum, frankincense, aconite, dried ginger, luffa, kuanjinteng, chicken blood vine, erythrina bark, and patchouli, forming a four-dimensional treatment system of "warming yang and dispelling cold, promoting blood circulation and unblocking collaterals, dispelling dampness and relaxing muscles, and aromatically resolving turbidity"; after processing with licorice water, the dosage of aconite is controlled within 5% of the total medicinal powder, ensuring that aconitine residue is ≤0.02%, thus the toxicity of the components is controllable; due to the addition of 6% patchouli, its volatile oil components neutralize the odor of mugwort smoke, reducing smoke particles by more than 30%, thus optimizing both the odor and the smoke.

[0065] Therefore, compared with traditional moxa sticks, the total clinical effective rate of the moxa sticks of this invention is increased by 25%-30%, and the therapeutic effect is greatly improved; moreover, it is safer (the toxicity of Aconitum carmichaelii is controllable) and has a more pleasant aroma (the aromatic aroma coverage of Patchouli is ≥85%).

[0066] 2. In terms of the preparation process, this invention utilizes nano-level pulverization and sieving to pulverize the medicinal materials to a fineness of over 100 mesh, thereby improving the transdermal absorption rate of the drug; through dynamic ratio control, i.e., mixing moxa wool and medicinal powder at a ratio of 3:1 and adding 5% honey water (diluted 1:1), the burning time is extended to 1520 minutes / stick; and through combustion stability design, i.e., designing the moxa stick density to be ≥0.8g / cm³, the invention achieves this. 3 This ensures that the invention does not experience flameout or scattering.

[0067] Therefore, compared with the traditional rolling process, the preparation process of this invention increases the release rate of the effective drug components by 40%; compared with ordinary moxa sticks, the combustion stability is improved (smoke volume is reduced by 35%, and ash integrity rate is ≥95%).

[0068] In summary, the present invention has the following advantages:

[0069] 1. Significantly improved efficacy: Patchouli enhances the dampness-resolving power, while the controlled proportion of Aconitum carmichaelii balances safety and efficacy. The synergistic effect of multi-target drugs results in an effective rate of ≥90% in treating shoulder pain due to cold-dampness obstruction.

[0070] 2. High safety: The use of limited processed Aconitum carmichaelii ensures controllable toxicity, with no skin irritation or allergic reactions. In addition, the addition of an appropriate amount of Tinospora sinensis can prevent excessive cooling.

[0071] 3. Excellent user experience: Honey binds the smoke more stably, and patchouli volatile oil reduces smoke particles; moreover, the aromatic components of patchouli mask the odor of moxa smoke, making it more acceptable to patients. Therefore, with less smoke and a pleasant aroma, patient acceptance increases by more than 50%. Detailed Implementation

[0072] The present invention will be further described below with reference to embodiments and experiments.

[0073] Example 1

[0074] A medicated moxa stick for treating shoulder pain due to cold and dampness obstruction, the medicated moxa stick comprising the following raw materials in parts by weight: 75 parts of moxa wool, 3 parts of horsehair flakes, 3 parts of frankincense, 5 parts of processed aconite root, 3 parts of dried ginger, 3 parts of *Luffa cylindrica*, 8 parts of *Tinospora sinensis*, 3 parts of *Spatholobus suberectus*, 3 parts of *Erythrina variegata* bark, and 6 parts of patchouli.

[0075] The processed Aconitum carmichaelii is a dried product after being soaked in licorice water, and the aconitine residue is ≤0.02%.

[0076] The specific preparation method of the moxa stick is as follows:

[0077] (1) Processing Aconitum carmichaelii: Slice Aconitum carmichaelii and soak it in 10% licorice water for 2 hours, then air dry it for later use.

[0078] (2) Grinding and sieving: Grind the following ingredients separately: horse antler powder, frankincense, processed aconite root, dried ginger, luffa cylindrica, kuanjin vine, chicken blood vine, erythrina bark, and patchouli, and sieve through a 100-mesh sieve to ensure fine powder.

[0079] (3) Mix the powders: Mix the powders according to the above weight proportions, add 5% honey water (1:1 dilution), and stir until it can be formed into a ball when squeezed in the hand and can be easily broken down when touched.

[0080] (4) Making moxa sticks:

[0081] 1) Mixing moxa floss and medicinal powder: Mix the well-stirred medicinal powder and moxa floss in a 1:3 ratio (i.e., 25g of medicinal powder + 75g of moxa floss), and knead by hand for 10 minutes to make it even.

[0082] 2) Rolling and shaping: Using an oak wood moxa stick rolling machine, the mixed materials are rolled into tight moxa sticks with a diameter of 1.5cm and a length of 20cm.

[0083] 3) Cut the moxa sticks: Cut the moxa sticks into 2cm long sections, each weighing about 3g, and seal them for storage in a dry, dark place.

[0084] Quality control methods

[0085] Combustion test: Light the moxa stick and observe the burning time (ideally 1520 minutes / stick), smoke volume (patchouli can reduce smoke by 30%), and whether there is any open flame falling off.

[0086] Safety testing: Processed Aconitum carmichaelii products passed the aconitine residue test (HPLC method): ≤0.02%; Medicated moxa sticks passed the particulate matter test of combustion smoke (PM2.5≤50μg / m³). 3 ).

[0087] Example 2

[0088] A medicated moxa stick for treating shoulder pain due to cold and dampness obstruction, the medicated moxa stick comprising the following raw materials in parts by weight: 70 parts of moxa wool, 2 parts of horsehair flakes, 2 parts of frankincense, 4 parts of processed aconite root, 3 parts of dried ginger, 2 parts of *Luffa cylindrica*, 8 parts of *Tinospora sinensis*, 3 parts of *Spatholobus suberectus*, 2 parts of *Erythrina variegata* bark, and 6 parts of patchouli.

[0089] The preparation method and quality control method of the traditional Chinese medicine moxa sticks in this embodiment are the same as those in Example 1, and will not be repeated here.

[0090] Example 3

[0091] A medicated moxa stick for treating shoulder pain due to cold and dampness obstruction, the medicated moxa stick comprising the following raw materials in parts by weight: 80 parts of moxa wool, 4 parts of *Zouma fetus*, 3 parts of frankincense, 4 parts of processed aconite root, 3 parts of dried ginger, 4 parts of *Ligusticum striatum*, 8 parts of *Tinospora sinensis*, 4 parts of *Spatholobus suberectus*, 3 parts of *Erythrina variegata* bark, and 7 parts of *Pogostemon cablin*.

[0092] The preparation method and quality control method of the traditional Chinese medicine moxa sticks in this embodiment are the same as those in Example 1, and will not be repeated here.

[0093] To verify the efficacy of the moxa sticks of this invention, the applicant also conducted experiments, user experience surveys, and interviews, obtaining the following data:

[0094] I. Clinical trial data (based on a multicenter randomized controlled trial)

[0095] Research Design:

[0096] Sample size: 240 patients with shoulder pain due to cold-dampness obstruction (meeting the diagnostic and therapeutic criteria of traditional Chinese medicine diseases) were randomly divided into 3 groups:

[0097] Experimental group (n=80): Using the moxa sticks of this invention (ginger-separated moxibustion, 3 cones per day)

[0098] Control group 1 (n=80): Traditional pure moxa sticks (treated using the same method)

[0099] Control group 2 (n=80): Commercially available moxa sticks containing moxa wool, chuanxiong rhizome, and cinnamon twig, applied using the same method.

[0100] Treatment course: 10 days / course, 2 courses in total, with a follow-up period of 1 month.

[0101] Evaluation indicators:

[0102] 1. Key indicators: VAS pain score (0-10 points), Constant-Murley shoulder function score (0-100 points)

[0103] 2. Secondary indicators: TCM syndrome score (Cold-Dampness Bi Syndrome Scale), inflammatory factors (IL-6, TNF-α), and safety (liver and kidney function, skin irritation).

[0104]

[0105]

[0106] Note: Overall effective rate = (Number of cured cases + Number of cases with significant improvement + Number of cases with improvement) / Total number of cases × 100% (Cure: Symptoms disappear and function recovers ≥90%; Significant improvement: Symptoms are reduced ≥70%)

[0107] Based on the above data, the onset time of the experimental group (3.2±1.1 days) was significantly shorter than that of control group 1 (5.8±1.5 days) and control group 2 (4.5±1.3 days) (p<0.01), indicating that the moxa stick of the present invention has significant therapeutic effect.

[0108] II. Mechanism of Action Data

[0109] 1. Anti-inflammatory and immune-modulating effects

[0110]

[0111] p<0.01: Experimental group vs. control group 1: The reduction of inflammatory factors reached 60-65%, which was significantly better than that of control group 1 (35-40%).

[0112] 2. Improved hemodynamics (detected by ultrasound)

[0113] Changes in shoulder joint blood flow: After 20 minutes of moxibustion, the brachial artery blood flow velocity increased by 85.7% in the experimental group (control group 1: 45.3%; control group 2: 62.1%), confirming the synergistic blood-activating effect of moxa wool + chicken blood vine + luffa.

[0114] III. Security and User Experience Data

[0115] 1. Security monitoring (n=240)

[0116]

[0117] 2. User experience questionnaire survey (n=240)

[0118] Experience items The experimental group was satisfied. Satisfaction of control group 1 Experience items Odor acceptability 92.5％ 41.3％ Odor acceptability Smoke irritation 88.8％ 33.8％ Smoke irritation Overall comfort 95.0％ 50.0％ Overall comfort

[0119] As can be seen from the above, the skin burn rate and allergic reaction rate of the moxa sticks of this invention are much lower than those of commercially available moxa sticks (control group 2), indicating that the moxa sticks of this invention have high safety. Meanwhile, the results of the user experience questionnaire also show that the odor acceptance of the moxa sticks of this invention is much higher than that of traditional moxa sticks, and the smoke irritation is also better than that of the traditional moxa stick group (control group 1), indicating that the moxa sticks of this invention have high odor acceptance, less irritation, higher overall comfort, and higher user satisfaction.

[0120] IV. Long-term follow-up data (recurrence rate after 1 month)

[0121] Group Relapse rate (symptom rebound ≥30%) experimental group 8.75％ Control group 1 32.50％ Control group 2 21.25％

[0122] The follow-up data above showed that the recurrence rate in the experimental group was low, which is related to the "muscle-strengthening and blood-nourishing" effect of the combination of *Vinealis kusnezoffii* and *Spatholobus suberectus* in this invention (electromyography showed that the frequency of muscle spasms decreased by 70%).

[0123] The above description is a detailed description of the preferred embodiments of the present invention. However, the embodiments are not intended to limit the scope of the patent application of the present invention. All equivalent changes or modifications made under the technical spirit of the present invention should fall within the patent scope covered by the present invention.

Claims

1. A moxa stick for treating shoulder pain due to cold-dampness obstruction, characterized in that, The medicinal moxa stick comprises the following raw materials in parts by weight: 70-80 parts of moxa wool, 2-5 parts of horsehair flakes, 1-5 parts of frankincense, 3-8 parts of processed aconite root, 1-5 parts of dried ginger, 1-5 parts of *Luffa cylindrica*, 5-10 parts of *Tinospora sinensis*, 1-5 parts of *Spatholobus suberectus*, 1-5 parts of *Erythrina variegata* bark, and 5-10 parts of patchouli.

2. The moxa stick according to claim 1, characterized in that, The medicinal moxa stick comprises the following raw materials in parts by weight: 75 parts of moxa wool, 3 parts of horsehair flakes, 3 parts of frankincense, 5 parts of processed aconite root, 3 parts of dried ginger, 3 parts of *Luffa cylindrica*, 8 parts of *Vinealis chinensis*, 3 parts of *Spatholobus suberectus*, 3 parts of *Erythrina variegata* bark, and 6 parts of patchouli.

3. The moxa stick according to claim 1, characterized in that, The processed Aconitum carmichaelii is a product dried after being soaked in 10% licorice water, with aconitine residue ≤0.02%.

4. The moxa stick according to claim 1, characterized in that, Honey water is added as a binder during the preparation of the moxa stick.

5. The moxa stick according to claim 1, characterized in that, The preparation method of the moxa stick is as follows: (1) Slice the prepared Aconitum carmichaelii, soak it in licorice water for 2 hours to obtain processed Aconitum carmichaelii, and dry it for later use. (2) Grind the following ingredients into powder: horse antler powder, frankincense, processed aconite root, dried ginger, luffa cylindrica, kuanjin vine, chicken blood vine, erythrina bark, and patchouli. Sift them to obtain the powders of each ingredient. (3) Weigh out each medicine powder according to the above weight proportions, mix them, add the adhesive honey water, and stir evenly; (4) Moxa stick forming: Mix the well-stirred medicinal powder and moxa wool at a ratio of 1:3, and roll the mixture into a tight moxa stick with a diameter of 1.5cm and a length of 20cm.

6. The moxa stick according to claim 5, characterized in that, The sieving in step (2) is sieving through a 100-mesh sieve.

7. The moxa stick according to claim 5, characterized in that, The honey water mentioned in step (3) is 5% honey water.

8. The moxa stick according to claim 1, characterized in that, The density of the moxa stick is greater than or equal to 0.8 g / cm³. 3 .

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