Broad-spectrum traditional Chinese medicine powder for resisting acid, protecting stomach and resisting alcohol injury and preparation method thereof

Abstract

The invention provides broad-spectrum anti-acid stomach-protecting anti-alcohol-injury traditional Chinese medicine powder and a preparation method thereof, and relates to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine powder is prepared from, by weight, 20-40 parts of cuttlebone, 10-20 parts of thunberg fritillary bulb, 5-10 parts of dried alum, 10-20 parts of pseudo-ginseng, 5-10 parts of coptis chinensis, 10-20 parts of amomum cardamomum, 3-8 parts of cinnamon, 15-25 parts of Chinese yam, 15-25 parts of radix paeoniae alba, 1-5 parts of dandelion and 5-10 parts of liquorice. According to the traditional Chinese medicine powder, 11 traditional Chinese medicinal materials such as the cuttlebone, the thunberg fritillary bulb and the dried alum are selected and scientifically matched, and the effects of the medicinal materials are complementary and synergistic. Cuttlebone and dried alum neutralize gastric acid and astringe to stop bleeding; pseudo-ginseng and coptis chinensis resist inflammation and repair gastric mucosa; cortex cinnamomi and round cardamom warm middle energizer and promote qi circulation; the liquorice harmonizes the medicines. Through the synergistic effect of multiple components, the traditional Chinese medicine composition not only can quickly relieve the symptoms such as acid regurgitation and belching and distention and fullness, but also can repair damaged gastric mucosa from the source and enhance the self-protection ability of the stomach, and has a more remarkable and comprehensive treatment effect compared with a single medicinal material or a conventional prescription.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine composition technology, and more specifically, it relates to a broad-spectrum antacid, stomach-protecting, and alcohol-damage-resistant traditional Chinese medicine powder and its preparation method. Background Technology

[0002] In modern life, stomach diseases have become a common ailment affecting people's health. Irregular eating habits, long-term alcohol consumption, and high levels of stress are contributing to a year-on-year increase in the incidence of diseases such as reflux esophagitis, erosive gastritis, and gastric ulcers, severely impacting patients' quality of life. Currently, treatments for stomach diseases mainly include traditional Chinese medicine and Western medicine, but both methods have certain limitations.

[0003] In terms of traditional Chinese medicine (TCM) treatment, while traditional herbal formulas have some effect on regulating stomach ailments, they often suffer from a lack of specificity. Many formulas target only a single syndrome or symptom; for example, some TCM formulas are only suitable for stomach pain due to cold stagnation in the stomach, and have little effect on patients with other syndromes such as stomach yin deficiency or liver qi invading the stomach. Moreover, traditional formulas contain a wide variety of medicinal materials, and the decoction process is complex, making it inconvenient for patients to take and difficult to adhere to long-term medication. Furthermore, some formulas cannot simultaneously relieve symptoms and repair the gastric mucosa, failing to fundamentally solve stomach problems, resulting in long treatment cycles and a high recurrence rate.

[0004] In terms of Western medicine treatment, while common antacids and gastric mucosal protectants can quickly relieve symptoms such as excessive stomach acid and stomach pain, long-term use can lead to numerous side effects. For example, proton pump inhibitors may cause liver and kidney damage, osteoporosis, and intestinal flora imbalance; long-term use of antacids such as magnesium aluminum carbonate may cause aluminum accumulation, adversely affecting the nervous system and bone health. Furthermore, most Western medicines only treat the symptoms and cannot regulate the body's overall physiological functions, failing to effectively improve the internal environment of the stomach. Symptoms are prone to relapse after discontinuation, making a complete cure difficult.

[0005] Especially for long-term drinkers, there is a lack of medications on the market that can effectively reduce alcohol damage to the gastric mucosa and comprehensively treat a variety of stomach diseases. Existing hangover relief and stomach protection products either focus on relieving discomfort symptoms after drinking, with limited effectiveness in treating stomach diseases; or they only target a specific stomach disease, failing to meet the complex and diverse stomach health needs of drinkers.

[0006] Therefore, developing a drug that can treat various gastric diseases through multiple targets and pathways, effectively combat alcohol damage, and is convenient and safe to take has become an urgent problem to be solved in the field of gastric disease treatment. The broad-spectrum antacid, gastric-protecting, and alcohol-damage-resistant traditional Chinese medicine powder and its preparation method provided by this invention are precisely aimed at overcoming the shortcomings of the existing technologies. Through scientific formulation and reasonable dosage form design, it provides a more effective treatment option for patients with gastric diseases and alcohol drinkers. Summary of the Invention

[0007] To address the aforementioned technical problems, this invention provides a broad-spectrum antacid, stomach-protecting, and alcohol-damage-resistant traditional Chinese medicine powder and its preparation method, thereby resolving the problems described above.

[0008] This broad-spectrum antacid, stomach-protecting, and alcohol-damage-resistant traditional Chinese medicine powder is composed of the following raw materials in parts by weight:

[0009] Cuttlebone 20-40 parts, Fritillaria thunbergii 10-20 parts, Alum 5-10 parts, Panax notoginseng 10-20 parts, Coptis chinensis 5-10 parts, Amomum villosum 10-20 parts, Cinnamomum cassia 3-8 parts, Dioscorea opposita 15-25 parts, Paeonia lactiflora 15-25 parts, Taraxacum mongolicum 1-5 parts, Glycyrrhiza uralensis 5-10 parts.

[0010] Preferably, it is composed of the following parts by weight of active pharmaceutical ingredient:

[0011] Cuttlebone 30 parts, Fritillaria thunbergii 15 parts, Alum 9 parts, Panax notoginseng 15 parts, Coptis chinensis 9 parts, Amomum villosum 15 parts, Cinnamomum cassia 6 parts, Dioscorea opposita 20 parts, Paeonia lactiflora 20 parts, Taraxacum mongolicum 3 parts, Glycyrrhiza uralensis 9 parts.

[0012] Preferably, the dosage form of the traditional Chinese medicine powder is a powder, the particle size of the powder is ≤150μm, and the method of taking the powder is as follows: twice a day, 6-9g each time, taken orally after being brewed with 50ml of boiling water before meals.

[0013] Preferably, the traditional Chinese medicine powder is used to treat acid reflux, belching, abdominal distension, reflux esophagitis, erosive gastritis, and gastric ulcer. The traditional Chinese medicine powder is used to treat stomach discomfort caused by long-term alcohol consumption. The traditional Chinese medicine powder is used to treat stomach pain caused by cold stagnation in the stomach, deficiency of stomach yin, liver qi invading the stomach, food damage to the stomach, and damp heat accumulation in the stomach.

[0014] Another technical problem to be solved by this invention is to provide a method for preparing a broad-spectrum antacid, stomach-protecting, and alcohol-damage-resistant traditional Chinese medicine powder, comprising the following steps:

[0015] S1: Weigh each raw material according to the weight proportions;

[0016] S2: Mix the raw materials and pulverize them, then pass them through a 100-mesh sieve to obtain a traditional Chinese medicine powder.

[0017] Preferably, the pulverization in step S2 uses ultrafine pulverization technology, and the particle size of the pulverized powder is ≤150μm.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] Synergistic Effect of Multiple Herbs for Comprehensive Combat of Stomach Discomfort: This invention scientifically combines 11 carefully selected Chinese medicinal herbs, including cuttlebone, fritillaria thunbergii, and alum, with each herb's effects complementing and synergizing. Cuttlebone and alum neutralize stomach acid and have astringent and hemostatic properties; Panax notoginseng and Coptis chinensis have anti-inflammatory and gastric mucosal repair effects; cinnamon and cardamom warm the middle jiao and promote qi circulation; and licorice harmonizes the effects of all the herbs. The synergistic effect of these multiple components can quickly relieve symptoms such as acid reflux, belching, and abdominal distension, while also repairing damaged gastric mucosa at its source and enhancing the stomach's self-protective ability. Compared to single herbs or conventional prescriptions, the therapeutic effect is more significant and comprehensive.

[0020] With broad applicability, this herbal powder covers a variety of gastric diseases and syndromes: it has good efficacy for common gastric diseases such as reflux esophagitis, erosive gastritis, and gastric ulcers, as well as various TCM syndromes such as cold stagnation in the stomach, stomach yin deficiency, and liver qi invading the stomach. Whether the stomach discomfort is caused by factors such as alcohol consumption, irregular eating habits, or emotional fluctuations, it can be treated with this herbal powder, breaking through the limitations of traditional drug treatments that target only a single symptom, and providing a wider and more effective option for the clinical treatment of gastric diseases.

[0021] Rapid onset of action and short recovery period: Extensive clinical case studies have verified that most patients experience significant relief from stomach pain and bloating within 1-3 days of medication, substantial symptom improvement within 1-2 weeks, and full recovery within 1-2 months. Compared to conventional Chinese herbal formulas and Western medicines, this invention's herbal powder can alleviate patient suffering more quickly, shorten the treatment cycle, and improve patients' quality of life.

[0022] Combating alcohol damage and meeting the needs of modern life: Especially suitable for people who drink alcohol regularly, it can effectively reduce the irritation and damage of alcohol to the gastric mucosa, relieve stomach discomfort symptoms after drinking, reduce the risk of diseases such as alcoholic gastritis and gastric ulcers, and provide effective protection for the stomach health of drinkers, which is in line with the characteristics of frequent social drinking in modern life.

[0023] Advantages of powder dosage form: convenient to take and high bioavailability: The powder dosage form involves pulverizing the medicinal materials through a 100-mesh sieve, resulting in small particle size that is easily dissolved and absorbed, allowing for rapid release of the medicinal effect. Furthermore, it only requires brewing with boiling water, eliminating the need for a complicated decoction process, making it convenient for patients to carry and take, and improving patient medication adherence.

[0024] High safety and few side effects: The formula consists of natural Chinese medicinal herbs. While ensuring efficacy, it has been clinically verified to have no obvious toxic side effects, avoiding the liver and kidney damage and drug resistance that may be caused by Western medicine. It is especially suitable for patients with chronic gastritis who need long-term medication, providing patients with a safe and reliable treatment plan.

[0025] The preparation process is scientific and the quality is stable and controllable: There are clear raw material quality control standards and standardized preparation processes. From the selection, weighing, and crushing of medicinal materials to sieving and packaging, each step has strict requirements to ensure stable product quality and uniform efficacy between different batches, which is conducive to large-scale industrial production and clinical application. Attached Figure Description

[0026] Figure 1 This is a schematic diagram of the components of the powder in this invention. Detailed Implementation

[0027] The embodiments of the present invention will be described in further detail below with reference to the accompanying drawings and examples. The following examples are for illustrative purposes only and should not be construed as limiting the scope of the invention.

[0028] Please see Figure 1 This invention provides a broad-spectrum antacid, stomach-protecting, and alcohol-damage-resistant traditional Chinese medicine powder and its preparation method. The traditional Chinese medicine powder is composed of the following raw materials in parts by weight:

[0029] Cuttlebone 20-40 parts, Fritillaria thunbergii 10-20 parts, Alum 5-10 parts, Panax notoginseng 10-20 parts, Coptis chinensis 5-10 parts, Amomum villosum 10-20 parts, Cinnamomum cassia 3-8 parts, Dioscorea opposita 15-25 parts, Paeonia lactiflora 15-25 parts, Taraxacum mongolicum 1-5 parts, Glycyrrhiza uralensis 5-10 parts.

[0030] Specific raw material selection and quality control:

[0031] The raw materials of the traditional Chinese medicine powder of this invention include cuttlebone, fritillaria thunbergii, alum, notoginseng, coptis chinensis, cardamom, cinnamon, yam, white peony root, dandelion, and licorice. The selection of each raw material plays a key role in the efficacy of the medicine, and its quality must be strictly controlled.

[0032] Cuttlebone: The dried inner shell of the cuttlefish (Sepia esculenta) or the golden cuttlefish (Sepia esculenta). High-quality cuttlebone should be white, pale yellow, or light yellowish-brown on the surface, with a layered cross-section, loose pores, a powdery texture, a slightly fishy odor, and a slightly salty taste. Its main components include calcium carbonate, which has antacid, analgesic, astringent, and hemostatic effects. In this invention, it is used to neutralize stomach acid and relieve symptoms such as acid reflux and belching. During procurement, it is necessary to have its calcium carbonate content tested by a professional institution to be no less than 90%, and the heavy metal content (lead, cadmium, arsenic, mercury, copper) must meet the relevant standards of the Chinese Pharmacopoeia.

[0033] Fritillaria thunbergii (Zhejiang Fritillaria): The dried bulb of the Fritillaria thunbergii plant (Liliaceae family). The best quality is characterized by thick bulbs, a whitish to pale yellow surface, a white or pale yellow cross-section, a powdery texture, a slight odor, and a bitter taste. Fritillaria thunbergii contains alkaloids such as fritillariaein, and has effects such as clearing heat and resolving phlegm, dispersing nodules and reducing swelling, and can relieve stomach fullness and distension. When purchasing, the fritillariaein content should be tested to ensure it is not less than 0.05% to guarantee efficacy.

[0034] Alum (calcined alum): a crystalline substance produced by processing and refining the sulfate mineral alunite. It appears as irregular lumps or granules, colorless or white, transparent or translucent, with a slightly smooth or uneven surface, fine longitudinal ridges, and a glassy luster. It has a faint odor and a sour, slightly sweet, and extremely astringent taste. In traditional Chinese medicine, alum can be used to astringe and heal sores, and inhibit gastric acid secretion. When purchasing alum, its purity must be at least 98%.

[0035] Panax notoginseng: The dried root and rhizome of Panax notoginseng, a plant in the Araliaceae family. The best quality is characterized by large size, heavy weight, firm texture, smooth surface, and a grayish-green or yellowish-green cross-section. Panax notoginseng contains effective components such as notoginsenosides, which can disperse blood stasis, stop bleeding, reduce swelling and relieve pain, and promote the repair of the gastric mucosa. When purchasing, ensure that the notoginsenoside content is not less than 5%.

[0036] Coptis chinensis: The dried rhizome of Coptis chinensis, Coptis triangularis, or Coptis chinensis (all belonging to the Ranunculaceae family). It has an extremely bitter taste. The best quality is characterized by its thick, firm rhizome with an orange-red bark and bright yellow or orange-yellow wood. Coptis chinensis contains alkaloids such as berberine and has the effects of clearing heat and drying dampness, purging fire and detoxifying. It can also inhibit gastric inflammation. When purchasing, the berberine content should be tested to ensure it is not less than 5.5%.

[0037] White cardamom: The dried, mature fruit of *Amomum villosum* or *Amomum javanica*, belonging to the ginger family. Its surface is yellowish-white to light yellowish-brown, with three deep longitudinal grooves. The apex has a protruding stylar base, and the base has a concave fruit stalk scar. Both ends are covered with light brown hairs. It has an aromatic odor and a pungent, cool taste, somewhat similar to camphor. White cardamom can resolve dampness, promote qi circulation, warm the stomach, and stop vomiting. In this invention, it can improve abdominal distension and fullness caused by qi stagnation in the spleen and stomach. When purchasing, the volatile oil content must be guaranteed to be no less than 4%.

[0038] Cinnamon: The dried bark of the cinnamon tree (Cinnamomum cassia), a plant in the Lauraceae family. It is trough-shaped or rolled, with a grayish-brown, slightly rough outer surface, sometimes showing grayish-white markings; the inner surface is reddish-brown, slightly flat, with fine longitudinal striations, leaving an oily mark when scratched. It has a strong aroma and a sweet, spicy taste. Cinnamon contains cinnamaldehyde and other components, which can invigorate yang, guide fire back to its source, dispel cold and relieve pain, and warm and unblock the meridians. It can alleviate pain caused by cold stagnation in the stomach. When purchasing, the cinnamaldehyde content should be tested to be no less than 1.0%.

[0039] Yam: The dried rhizome of Dioscorea opposita, a plant in the Dioscoreaceae family. The best quality yam is thick, firm, starchy, and white. Rich in starch and mucilage, yam has the effects of tonifying the spleen and stomach, promoting body fluid production, and benefiting the lungs. It can enhance spleen and stomach function. When purchasing yam, ensure the starch content is not less than 70%.

[0040] White peony root: The dried root of the peony plant (Paeonia lactiflora), belonging to the Ranunculaceae family. It has a light reddish-brown or off-white surface, is smooth, firm, and not easily broken. The cross-section is relatively flat, off-white or slightly reddish-brown, with a distinct cambium ring and radial rays. It has a faint odor and a slightly bitter and sour taste. White peony root contains paeoniflorin and other components, which can nourish blood and regulate menstruation, astringe yin and stop sweating, soothe the liver and relieve pain. It can alleviate pain caused by liver qi invading the stomach. When purchasing, the paeoniflorin content should be tested to be no less than 1.6%.

[0041] Dandelion: The dried whole herb of *Taraxacum officinale*, *Taraxacum mongolicum*, or several species of the same genus in the Asteraceae family. The best quality is characterized by abundant leaves, a green color, and robust roots. Dandelion contains taraxasterol and other components, possessing properties such as clearing heat and detoxifying, reducing swelling and dissipating nodules. It can be used as an adjunct treatment for gastritis. When purchasing, ensure the taraxasterol content is not less than 0.2%.

[0042] Licorice: The dried root and rhizome of *Glycyrrhiza uralensis*, *Glycyrrhiza inflata*, or *Glycyrrhiza glabra*, all belonging to the legume family. The best quality licorice is characterized by its fine, tight skin, reddish-brown color, firm texture, yellowish-white cross-section, high starch content, and sweet taste. Licorice contains glycyrrhizin and other components, and can tonify the spleen and replenish qi, clear heat and detoxify, and harmonize the effects of other herbs. In traditional Chinese medicine formulas, it plays a coordinating role in the efficacy of various medicinal materials. When purchasing licorice, the glycyrrhizin content should be tested to ensure it is not less than 5.0%.

[0043] Preparation of Chinese herbal powders:

[0044] Example 1:

[0045] Raw material weighing: According to the ratio of 30g cuttlebone, 15g Fritillaria thunbergii, 9g alum, 15g Panax notoginseng, 9g Coptis chinensis, 15g Amomum villosum, 6g cinnamon, 20g Dioscorea opposita, 20g Paeonia lactiflora, 3g Taraxacum mongolicum, and 9g Glycyrrhiza uralensis, each raw material was accurately weighed using a high-precision electronic balance (accuracy 0.01g).

[0046] Mixing and Grinding: Place the weighed raw materials into a stainless steel mixing container and stir at low speed for 10 minutes to initially mix the raw materials evenly. Then transfer them to a traditional Chinese medicine grinder for grinding. During the grinding process, control the grinder speed at 1500 r / min and the grinding time at 30 minutes to grind the raw materials into fine powder.

[0047] Sieving process: The pulverized powder is passed through a 100-mesh sieve. Coarse powder that fails to pass through the sieve is returned to the pulverizer for secondary pulverization until all powder passes through the 100-mesh sieve, thus obtaining the traditional Chinese medicine powder. Testing showed that the particle size of this traditional Chinese medicine powder is ≤150μm.

[0048] Packaging and storage: Divide the prepared Chinese herbal powder into sealed medicinal plastic bags, 9g per bag, and store in a cool, dry place, avoiding moisture and direct sunlight.

[0049] Example 2:

[0050] Raw material weighing: Weigh 20g of cuttlebone, 10g of fritillaria thunbergii, 5g of alum, 10g of notoginseng, 5g of coptis chinensis, 10g of cardamom, 3g of cinnamon, 15g of yam, 15g of white peony root, 1g of dandelion, and 5g of licorice.

[0051] Mixing and pulverizing: First, manually grind and mix the raw materials in a ceramic mortar for 5 minutes, then put them into an ultra-fine pulverizer, set the pulverizing temperature to 25℃, the pulverizing time to 40 minutes, and the rotation speed to 2000r / min for ultra-fine pulverization.

[0052] Sieving process: The pulverized powder is passed through a 100-mesh sieve. Any particles that do not pass through the sieve are pulverized again until all particles pass through the sieve. The particle size of the powder is then tested, and all particles meet the requirement of ≤150μm.

[0053] Packaging and storage: Divide the Chinese herbal powder into brown glass bottles, 6g per bottle, seal and store in a cool, dark place.

[0054] Example 3:

[0055] Raw material weighing: Take 40g of cuttlebone, 20g of fritillaria thunbergii, 10g of alum, 20g of notoginseng, 10g of coptis chinensis, 20g of cardamom, 8g of cinnamon, 25g of yam, 25g of white peony root, 5g of dandelion, and 10g of licorice.

[0056] Mixing and pulverizing: Mix the raw materials with a V-type mixer for 15 minutes, and then pulverize them with an air jet mill, controlling the airflow speed at 30 m / s and the pulverizing time at 25 minutes.

[0057] Sieving process: The pulverized powder is passed through a 100-mesh sieve to ensure that all powder passes through. After testing, the powder particle size meets the standard.

[0058] Packaging and storage: Pack the Chinese herbal powder into aluminum foil bags, 8g per bag, seal and store in a dry and ventilated place.

[0059] Dosage and administration instructions:

[0060] The method of administration for this herbal powder is twice daily, 6-9g each time, dissolved in 50ml of boiling water before meals and taken orally. In practical application, the dosage can be adjusted appropriately according to the patient's age, severity of condition, and other factors. For example, for patients with milder conditions, the dosage can start at 6g each time; for patients with more severe conditions or larger weight, the dosage can be increased to 9g each time. The dosage for children should be calculated according to their age and weight, generally 1 / 3 to 1 / 2 of the adult dosage. When taking the medicine, pour the herbal powder into a cup, add 50ml of boiling water, stir well, and take it orally after the temperature is suitable. To ensure efficacy, it is recommended to take it about 30 minutes before meals so that the medicine can act better on the stomach.

[0061] Clinical application examples:

[0062] Case 1: Stomach pain due to cold stagnation in the stomach:

[0063] Patient Jin Shuquan, male, 44 years old, village cadre, consulted on February 7, 2025. Chief complaint: recurrent stomach pain for 5 years, worsening in the past week. Present illness history: The patient began experiencing stomach discomfort 5 years ago due to excessive alcohol consumption. Symptoms worsened with irregular eating habits and alcohol consumption, and had significantly intensified in the past week, accompanied by heartburn and acid reflux. Pulse was wiry, deep, and slightly tense; tongue coating was dark red with a thick, bluish-purple edge. Traditional Chinese medicine diagnosis: stomach pain syndrome (cold stagnation in the stomach). The patient was prescribed the herbal powder of this invention (prepared in Example 1), 9 grams, dissolved in 50ml of boiling water and taken orally twice daily before meals. After one week of medication, the patient's stomach pain symptoms significantly decreased; after continuing medication for one month, the stomach pain symptoms disappeared, and appetite returned to normal. A follow-up gastroscopy showed significant improvement in gastric mucosal inflammation.

[0064] Case 2: Stomach pain due to deficiency of stomach yin:

[0065] Patient Wang Weiwei, female, 40 years old, office worker, consulted on November 20, 2024. Chief complaint: bloating, nausea, and vomiting for 2 months, worsening in the past 20 days. Present illness history indicates that the patient experienced recurrent nausea, vomiting, and stomach discomfort due to early pregnancy 2 months prior, with difficulty eating. Symptoms significantly worsened in the past 20 days, accompanied by constipation. Pulse was deep and thready; tongue coating was red with little coating and slight cracks. Traditional Chinese medicine diagnosis was stomach pain syndrome (stomach yin deficiency). She was prescribed the herbal powder of this invention (prepared in Example 2), 9 grams, dissolved in 50ml of boiling water and taken orally twice daily before meals. After one week of medication, the bloating symptoms significantly improved; after continuing medication for two weeks, the stomach pain symptoms disappeared, she returned to a normal diet, and her constipation was also relieved.

[0066] Case 3: Stomach pain due to liver qi invading the stomach:

[0067] Patient Yan Xuemei, female, 35 years old, waitress, consulted on March 24, 2025. Chief complaint: burning pain in the stomach for one month. Present illness: The patient experienced stomach pain due to emotional fluctuations, accompanied by bloating, hypochondriac pain, dry mouth and throat, irritability, and anger, which worsened with emotional changes. Pulse was wiry, slippery, and slightly rapid; tongue coating was red at the edges with a thin yellow coating. Traditional Chinese medicine diagnosis was stomach pain syndrome (liver qi invading the stomach). Treatment involved the use of the herbal powder of this invention (prepared in Example 3), 9 grams dissolved in 50 ml of boiling water, taken orally twice daily before meals. After one week of medication, the patient's burning stomach pain disappeared, her mood improved, and no recurrence was observed during subsequent follow-up.

[0068] Case 4: Stomach pain caused by food irritation:

[0069] Patient Chen Xinyu, female, 24 years old, nurse, presented on December 24, 2024. Chief complaint: recurrent stomach pain for 3 months. Present illness: The patient experienced abdominal distension and pain due to improper diet; the pain was relieved after vomiting undigested food, but she also experienced loss of appetite and incomplete bowel movements. Her pulse was strong and forceful, and her tongue coating was thick and greasy. The TCM diagnosis was stomach injury due to improper diet. She was prescribed the herbal powder of this invention (prepared in Example 1), 6 grams, dissolved in 50ml of boiling water and taken orally twice daily before meals. After 3 days of medication, the patient's stomach pain disappeared, her appetite returned, and her bowel movements normalized.

[0070] Case 5: Stomach pain due to damp-heat accumulation in the stomach:

[0071] Patient Qi Hongliang, male, 37 years old, chef, consulted on February 15, 2025. Chief complaint: recurrent stomach pain for one month. Present illness: the patient experienced burning pain in the epigastric region due to dietary indiscretion, accompanied by dry mouth, bitter taste, and yellow urine. Pulse was slippery and rapid; tongue coating was red with a thick, greasy yellow coating. Traditional Chinese medicine diagnosis: damp-heat accumulation in the stomach. He was prescribed the herbal powder of this invention (prepared in Example 2), 9 grams, dissolved in 50ml of boiling water and taken orally twice daily before meals. After seven days of medication, the patient's stomach pain disappeared, and the dry mouth, bitter taste, and yellow urine also subsided.

[0072] Comparison of proportions and effects:

[0073] (a) Comparative Example 1: Single Medicinal Herb Group

[0074] Cuttlebone was selected and prepared into a powder according to the preparation method of this invention. The dosage was 9g each time, twice a day, taken orally before meals after being dissolved in 50ml of boiling water. This was used to treat 10 patients with acid reflux and belching. After one week of treatment, only 3 patients showed slight symptom relief, while the remaining patients showed no significant improvement. After one month of treatment, 4 patients still had persistent symptoms. Compared with Example 1 of this invention, the single cuttlebone powder was significantly less effective in relieving stomach discomfort symptoms in both speed and efficacy, indicating that the combination of multiple medicinal materials in this invention has a synergistic effect.

[0075] (ii) Comparative Example 2: Conventional Chinese Medicine Group

[0076] Commonly available traditional Chinese medicine formulas for treating stomach ailments (excluding the alum, dandelion, and other medicinal materials used in this invention) were selected and treated in 10 patients with gastric ulcers according to their conventional preparation methods and dosages. After one month of treatment, 6 patients experienced symptom relief, but 4 patients still had symptoms such as stomach pain and bloating; after three months of treatment, 2 patients were still not fully recovered. In contrast, among the 10 patients with gastric ulcers treated using Example 3 of this invention, 8 patients experienced symptom disappearance after one month of treatment, and 2 patients experienced significant symptom relief; after two months of treatment, all patients recovered. The comparative results indicate that the traditional Chinese medicine powder of this invention has better efficacy and faster recovery speed in treating stomach ailments.

[0077] (III) Comparative Example 3: Western Medicine Group

[0078] Ten patients with reflux esophagitis were treated with a brand of antacid and gastric mucosal protectant, following the dosage and administration instructions. After one week of treatment, heartburn and acid reflux symptoms were relieved in 7 patients, but symptoms did not improve in 3 patients; after one month of treatment, symptoms recurred in 2 patients. In contrast, among the 10 patients with reflux esophagitis treated with Example 2 of this invention, symptoms were significantly reduced in 8 patients after one week of treatment; after two weeks of treatment, symptoms disappeared in 9 patients, and symptoms were basically relieved in 1 patient. Furthermore, in subsequent follow-up, the recurrence rate in the treatment group was significantly lower than that in the Western medicine group, indicating that the herbal powder of this invention not only effectively relieves symptoms but also fundamentally improves the gastric environment and reduces the risk of disease recurrence.

[0079] As can be seen from the above examples and comparative examples, the broad-spectrum anti-acid, stomach-protecting, and alcohol-damage-resistant traditional Chinese medicine powder of the present invention and its preparation method, through reasonable combination of medicinal materials and scientific preparation process, have significant effects in treating a variety of gastric diseases, can quickly relieve symptoms, promote patient recovery, and have a low recurrence rate, thus having good clinical application value and broad market prospects.

[0080] The embodiments of the present invention are given for illustrative and descriptive purposes only, and are not intended to be exhaustive or to limit the invention to the forms disclosed. Many modifications and variations will be apparent to those skilled in the art. The embodiments were chosen and described in order to better illustrate the principles and practical application of the invention, and to enable those skilled in the art to understand the invention and to design various embodiments with various modifications suitable for a particular purpose.

Claims

1. A broad-spectrum antacid, stomach-protecting, and alcohol-damage-resistant traditional Chinese medicine powder, characterized in that, Composed of the following parts by weight of active pharmaceutical ingredient: Cuttlebone 20-40 parts, Fritillaria thunbergii 10-20 parts, Alum 5-10 parts, Panax notoginseng 10-20 parts, Coptis chinensis 5-10 parts, Amomum villosum 10-20 parts, Cinnamomum cassia 3-8 parts, Dioscorea opposita 15-25 parts, Paeonia lactiflora 15-25 parts, Taraxacum mongolicum 1-5 parts, Glycyrrhiza uralensis 5-10 parts.

2. The traditional Chinese medicine powder according to claim 1, characterized in that, Composed of the following parts by weight of active pharmaceutical ingredient: Cuttlebone 30 parts, Fritillaria thunbergii 15 parts, Alum 9 parts, Panax notoginseng 15 parts, Coptis chinensis 9 parts, Amomum villosum 15 parts, Cinnamomum cassia 6 parts, Dioscorea opposita 20 parts, Paeonia lactiflora 20 parts, Taraxacum mongolicum 3 parts, Glycyrrhiza uralensis 9 parts.

3. The traditional Chinese medicine powder according to claim 1 or 2, characterized in that, The dosage form of the Chinese herbal powder is a powder.

4. The traditional Chinese medicine powder according to claim 3, characterized in that, The powder particle size of the traditional Chinese medicine powder is ≤150μm.

5. The traditional Chinese medicine powder according to claim 3, characterized in that, The method of taking the Chinese herbal powder is as follows: twice a day, 6-9g each time, taken orally after being brewed with 50ml of boiling water before meals.

6. The traditional Chinese medicine powder according to claim 1, characterized in that, The traditional Chinese medicine powder is used to treat acid reflux, belching, abdominal distension, reflux esophagitis, erosive gastritis, and gastric ulcers.

7. The traditional Chinese medicine powder according to claim 1, characterized in that, The herbal powder is used to treat stomach discomfort caused by long-term alcohol consumption.

8. The traditional Chinese medicine powder according to claim 1, characterized in that, The Chinese herbal powder is used to treat stomach pain caused by cold stagnation in the stomach, deficiency of stomach yin, liver qi invading the stomach, food injury to the stomach, and damp heat accumulation in the stomach.

9. A method for preparing a traditional Chinese medicine powder as described in any one of claims 1-8, characterized in that, Includes the following steps: S1: Weigh each raw material according to the weight proportions; S2: Mix the raw materials and pulverize them, then pass them through a 100-mesh sieve to obtain a traditional Chinese medicine powder.

10. The preparation method according to claim 9, characterized in that, In step S2, ultrafine grinding technology is used to pulverize the powder, and the particle size of the pulverized powder is ≤150μm.

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