Filtering device for pharmaceutical equipment
By introducing a step-by-step discharge unit and an auxiliary discharge mechanism into the filtration device, and using airbags and pneumatic control components to drive the filtration membrane to fluctuate, the problem of filtration membrane clogging is solved, achieving a highly efficient and uniform filtration effect, and ensuring the sealing performance and filtration efficiency of the filtration membrane.
Patent Information
- Application Number
- CN202511554972.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-29
- Publication Date
- 2026-02-24
- Estimated Expiration
- 2045-10-29
AI Technical Summary
The filter membrane is prone to clogging during the filtration process, especially on the side near the guide hole between the feed chamber and the filter chamber, which leads to poor material discharge and affects the normal filtration effect of the liquid.
A filtration device including a filter tank body is designed, which is internally equipped with a drive chamber, a mixing chamber, a stirring chamber and a filter chamber. The filter chamber is equipped with a step-by-step discharge unit and an auxiliary discharge mechanism. The auxiliary discharge mechanism drives the filter membrane to fluctuate up and down through an airbag and a pneumatic control component to avoid impurity accumulation. A detachable inner and outer connecting membrane and an elastic thin film structure are adopted to ensure the sealing of the filter layer.
It effectively avoids local clogging of the filter membrane, improves filtration efficiency, ensures the uniformity and sealing of the filter membrane, prevents liquid leakage, and enhances the filtration effect.
Smart Images

Figure CN121041862B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of biopharmaceutical equipment technology, specifically a filtration device for pharmaceutical equipment. Background Technology
[0002] Biopharmaceuticals is a technology that utilizes biotechnology, using microorganisms, plant and animal cells, or genetically engineered biological systems as production factories, to prepare drugs for the prevention, treatment, or diagnosis of diseases. Core products include recombinant protein drugs, monoclonal antibodies, and vaccines. The production process in this field is highly precise, requiring specialized pharmaceutical equipment to achieve efficient and compliant production. Filtration devices are one of the key pieces of equipment. During the fermentation and culture stage, filtration devices remove impurities and microbial contaminants from the culture medium. In the downstream purification stage, devices such as deep filtration and membrane filtration separate cell debris, nucleic acids, and other proteins, ensuring the purity and safety of the target drug components. It is a crucial technological support connecting biosynthesis and the final drug formulation, directly impacting drug quality and production efficiency.
[0003] A search revealed a Chinese patent (CN114602239B) disclosing a tangential flow intelligent filtration device for biopharmaceutical applications. The device includes a filter tank body with a feed chamber and a filter chamber arranged sequentially from top to bottom. The feed chamber is connected to a feed hopper, and a guide hole is provided between the feed chamber and the filter chamber. A spiral filter assembly is vertically arranged within the filter chamber. The spiral filter assembly includes a sleeve located within the filter chamber and a spiral guide plate located on the outer wall of the sleeve. The spiral guide plate includes an inner guide plate fixedly connected to the sleeve and an outer guide plate fixedly connected to the inner guide plate. A filter membrane is detachably connected between the inner and outer guide plates. A collection box is located below the filter membrane, and a material collection pipe is connected to the bottom of the collection box. A liquid collection pipe is located at the bottom of the filter chamber. The spiral guide plate increases the contact area between the filter membrane and the liquid, improving the filtration effect. Furthermore, tangential filtration is achieved by utilizing the downward flow of the liquid's own gravity, thus saving costs.
[0004] However, in actual use, the filtration membrane still suffers from poor material discharge when filtering the liquid, especially the filtration membrane closest to the guide hole between the feed chamber and the filter chamber. Because it comes into contact with the liquid with a larger material content first, the amount of material on the filtration membrane in the area closest to the guide hole is greater than that on the filtration membrane in the subsequent areas. Although the flow of the liquid can carry some material along the spiral filtration membrane, the filtration membrane in the area closest to the guide hole will still become clogged. Similarly, the subsequent areas will gradually become clogged. This situation directly affects the normal filtration of the liquid, causing some liquid to be discharged directly from the material collection pipe, thus affecting the filtration effect. To address this, we propose a filtration device for pharmaceutical equipment. Summary of the Invention
[0005] One technical problem this application aims to solve is that the material discharge effect of the filter membrane is still poor when filtering the liquid, especially the filter membrane closest to the guide hole between the feed chamber and the filter chamber. Because it is the first to come into contact with the liquid with a large material content, the amount of material on the filter membrane in the area closest to the guide hole is greater than that on the filter membrane in the subsequent areas. Although the flow of the liquid can carry some material along the spiral filter membrane, the filter membrane in the area closest to the guide hole will still become clogged. Similarly, the subsequent areas will gradually become clogged. This situation will directly affect the normal filtration of the liquid, causing some liquid to be discharged directly from the material collection pipe, thus affecting the filtration effect of the liquid.
[0006] To address the aforementioned technical problems, this application provides a filtration device for pharmaceutical equipment, comprising a filter tank body. The filter tank body has, from top to bottom, a driving chamber, a mixing chamber, a stirring chamber, and a filtering chamber, separated by a first partition and a second partition. A rotating shaft is located at the bottom center of the second partition. Inside the filtering chamber, a step-by-step discharge unit is arranged around the rotating shaft. The step-by-step discharge unit includes a filter membrane. The surface of the filter membrane has several movable grooves with equal spacing between them. An elastic membrane is disposed inside each movable groove. An auxiliary discharge mechanism is located at the bottom of the filter membrane inside the filtering chamber, and this auxiliary discharge mechanism is used to lift the middle of the filter membrane.
[0007] In some embodiments, the step-by-step discharge unit further includes an inner guide plate connected to a rotating shaft and an outer guide plate connected to the inner wall of the filter chamber. An inner connecting membrane is installed at one end of the inner guide plate opposite to the outer guide plate, and an outer connecting membrane is installed at one end of the outer guide plate opposite to the inner guide plate. The filter membrane is disposed between the inner connecting membrane and the outer connecting membrane.
[0008] In some embodiments, both the inner and outer connecting membranes are detachably connected, and the inner and outer connecting membranes stretch as the filter membrane undulates.
[0009] In some embodiments, the auxiliary discharge mechanism includes a plurality of air bladders disposed on the underside of the filter membrane, each air bladder being located between every two movable slots, one end of each air bladder being connected to a pneumatic control component, the end of the pneumatic control component away from the air bladder being connected to a flexible tube, and the end of the flexible tube away from the pneumatic control component being connected to the end of the adjacent air bladder away from the pneumatic control component.
[0010] In some embodiments, the airbags are all made of rubber.
[0011] In some embodiments, the pneumatic control assembly includes a housing with air outlets at both ends. A spring and an elastic ball are disposed inside the pneumatic control assembly. The two ends of the spring press against the housing and the elastic ball, respectively. The outer diameter of the elastic ball is larger than the inner diameter of the air outlet. The housing is mounted on a rotating shaft via a mounting rod.
[0012] In some embodiments, the end of the air control component on the uppermost airbag is connected to an air pump via an extension tube, which passes through the filter tank and extends to the outside of the filter tank.
[0013] In some embodiments, the lowermost airbag is connected to an air pump at the end away from the air control component via an extension tube 2, which penetrates the filter tank and extends to the outside of the filter tank.
[0014] In some embodiments, the surface of the second partition plate has a material leakage hole on the upper side of the starting end of the filter membrane.
[0015] In some embodiments, a baffle plate is provided on the filter tank body at the mixing chamber, and a liquid recovery mechanism is provided on the rear side of the filter tank body. The liquid recovery mechanism and the feed hopper are connected by a recovery pipe.
[0016] The present invention has at least the following beneficial effects: 1. In the present invention, by setting an auxiliary discharge mechanism, the filter membrane is driven to fluctuate up and down. When the filter membrane fluctuates, impurities in the liquid will flow to both sides with the fluctuation of the membrane surface, avoiding the uneven phenomenon of a large amount of impurities accumulating at the front and a small amount accumulating at the back of the filter membrane surface, thus avoiding local blockage of the filter membrane and a decrease in overall filtration efficiency. 2. In the present invention, by setting a gas control component, a one-way sealing structure can be formed. The airflow is opened and stopped when it enters, which helps the filter membrane to fluctuate stably and improves the filtration effect. 3. In the present invention, by setting a movable groove along the transverse direction on the surface of the filter membrane, and installing an elastic membrane in the movable groove, the filter membrane forms an interconnected sheet structure with a flexible foundation that can fluctuate; at the same time, the inner connecting membrane and the outer connecting membrane have a certain tensile properties. When the filter membrane is lifted by the auxiliary discharge mechanism, the two will stretch synchronously with the deformation of the filter membrane. The elastic wave membrane ensures that the filter layer always remains intact and sealed, avoiding leakage of the liquid. Attached Figure Description
[0017] Figure 1 This is a schematic diagram of the overall structure of the present invention;
[0018] Figure 2 This is a schematic diagram of the overall internal structure of the present invention;
[0019] Figure 3 This is a side view of the filter tank body of the present invention.
[0020] Figure 4 This is a schematic diagram of the other side of the filter tank body of the present invention;
[0021] Figure 5 This is a schematic diagram of the step-by-step material discharge unit structure of the present invention;
[0022] Figure 6 This is a schematic diagram of the auxiliary material feeding mechanism of the present invention;
[0023] Figure 7 For the present invention Figure 5 Enlarged schematic diagram of the structure at point A in the middle;
[0024] Figure 8 For the present invention Figure 6 Enlarged schematic diagram of the structure at point B.
[0025] In the diagram: 1. Filter tank body; 11. Drive chamber; 12. Mixing chamber; 121. Partition 1; 13. Stirring chamber; 131. Partition 2; 1311. Leakage hole; 14. Filter chamber; 2. Feed hopper; 3. Liquid recovery mechanism; 4. Recovery pipe; 5. Rotating shaft; 6. Step-by-step discharge unit; 61. Inner guide plate; 62. Outer guide plate; 63. Inner connecting membrane; 64. Outer connecting membrane; 65. Filter membrane; 66. Movable trough; 7. Auxiliary discharge mechanism; 71. Airbag; 72. Pneumatic control component; 721. Housing shell; 722. Spring; 723. Elastic ball; 73. Hose; 74. Mounting rod; 8. Suction pump; 9. Blowing pump. Detailed Implementation
[0026] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0027] Example 1: Please refer to Figures 1-8This invention provides a technical solution: a filtration device for pharmaceutical equipment, comprising a filtration tank 1. The interior of the filtration tank 1, from top to bottom, comprises a driving chamber 11, a mixing chamber 12, a stirring chamber 13, and a filtration chamber 14. The mixing chamber 12, stirring chamber 13, and filtration chamber 14 are separated by a first partition 121 and a second partition 131. A rotating shaft 5 is located at the bottom center of the second partition 131. Inside the filtration chamber 14, a step-by-step discharge unit 6 is arranged around the rotating shaft 5. The step-by-step discharge unit 6 includes a filter membrane 65, the surface of which has several... The movable troughs 66 are spaced equally apart and have an elastic membrane inside. An auxiliary discharge mechanism 7 is provided inside the filter chamber 14 at the bottom of the filter membrane 65. The auxiliary discharge mechanism 7 is used to lift the middle part of the filter membrane 65. A leakage hole 1311 is opened on the surface of the second partition plate 131 above the starting end of the filter membrane 65. A first partition plate 121 is provided on the filter tank body 1 at the mixing chamber 12. A liquid recovery mechanism 3 is provided on the rear side of the filter tank body 1. The liquid recovery mechanism 3 and the feed hopper 2 are connected by a recovery pipe 4.
[0028] The drive chamber 11 is located at the top of the filter tank 1 and contains a power unit to drive the mixing chamber 12, stirring chamber 13 and filtering chamber 14. The biopharmaceutical liquid to be filtered is poured into the feed hopper 2. The liquid first enters the mixing chamber 12 and is initially mixed. The mixed liquid enters the stirring chamber 13 through the first partition 121. The components in the stirring chamber 13 agitate the liquid and further disperse the agglomerated particles. Then, under its own gravity, the liquid is transported to the starting end of the filter membrane 65 in the filtering chamber 14 through the leakage hole 1311 on the second partition 131. The liquid that is not completely filtered or needs secondary purification in the filtering chamber 14 enters the liquid recovery mechanism 3. After being collected by the liquid recovery mechanism 3, it is transported back to the feed hopper 2 through the recovery pipe 4 and re-enters the mixing chamber 12 to start a new round of filtration.
[0029] Example 2: Please refer to Figures 1-8 The present invention provides a technical solution: a filtration device for pharmaceutical equipment, wherein the step-by-step discharge unit 6 further includes an inner guide plate 61 connected to the rotating shaft 5 and an outer guide plate 62 connected to the inner wall of the filter chamber 14. An inner connecting membrane 63 is installed at one end of the inner guide plate 61 opposite to the outer guide plate 62, and an outer connecting membrane 64 is installed at one end of the outer guide plate 62 opposite to the inner guide plate 61. A filter membrane 65 is disposed between the inner connecting membrane 63 and the outer connecting membrane 64. Both the inner connecting membrane 63 and the outer connecting membrane 64 are detachably connected, and the inner connecting membrane 63 and the outer connecting membrane 64 are stretched as the filter membrane 65 fluctuates.
[0030] In addition to the filter membrane 65, the step-by-step discharge unit 6 also includes an inner guide plate 61 and an outer guide plate 62. The inner guide plate 61 is fixedly connected to the outer wall of the rotating shaft 5, and the outer guide plate 62 is fixedly connected to the inner wall of the filter chamber 14. The two are arranged opposite to each other to form the mounting frame of the filter membrane 65. At the opposite ends of the inner guide plate 61 and the outer guide plate 62, an inner connecting membrane 63 and an outer connecting membrane 64 are respectively installed. The filter membrane 65 is sandwiched between the inner connecting membrane 63 and the outer connecting membrane 64 to form a complete filter layer. To facilitate the replacement of filter membranes 65 of different specifications to adapt to different liquid filtration needs, both the inner connecting membrane 63 and the outer connecting membrane 64 are designed as detachable connection structures. The auxiliary discharge mechanism 7 can drive the filter membrane 65 to fluctuate up and down. When the filter membrane 65 fluctuates... When in motion, impurities in the feed solution will flow to both sides with the undulation of the membrane surface, avoiding the uneven accumulation of impurities in the biopharmaceutical feed solution to be filtered on the surface of the filter membrane 65, where a large amount accumulates at the front and a small amount accumulates at the back, thus preventing local clogging of the filter membrane 65 and a decrease in overall filtration efficiency. To cooperate with the driving action of the auxiliary discharge mechanism 7, the surface of the filter membrane 65 is provided with a movable groove 66 along the transverse direction, and an elastic membrane is installed in the movable groove 66, so that the filter membrane 65 forms an interconnected sheet structure with a flexible foundation that can fluctuate. At the same time, the inner connecting membrane 63 and the outer connecting membrane 64 have a certain tensile properties. When the filter membrane 65 is lifted by the auxiliary discharge mechanism 7, the two will stretch synchronously with the deformation of the filter membrane 65. The elastic membrane ensures that the filter layer always remains intact and sealed, preventing feed solution leakage.
[0031] Example 3: Please refer to Figures 1-8 This invention provides a technical solution: a filtration device for pharmaceutical equipment, wherein the auxiliary discharge mechanism 7 includes multiple air bladders 71 disposed on the lower side of the filter membrane 65, each air bladder 71 being located between every two movable slots 66, one end of each air bladder 71 being connected to a pneumatic control component 72, the end of the pneumatic control component 72 away from the air bladder 71 being connected to a flexible hose 73, the end of the flexible hose 73 away from the pneumatic control component 72 being connected to the end of an adjacent air bladder 71 away from the pneumatic control component 72, all air bladders 71 being made of rubber, the pneumatic control component 72 including a housing 721, both ends of the housing 721 having air outlets, a spring 722 disposed inside the pneumatic control component 72, and an elastic ball 723 disposed inside the pneumatic control component 72, the two ends of the spring 722 pressing on the housing 721 and the elastic ball 723 respectively, the outer diameter of the elastic ball 723 being larger than the inner diameter of the air outlet, the housing 721 being mounted on a rotating shaft 5 via a mounting rod 74.
[0032] Multiple airbags 71 are disposed on the underside of the filter membrane 65, with each airbag 71 positioned precisely between every two adjacent movable slots 66. This ensures that when the airbag 71 inflates, it acts precisely on the non-slotted area of the filter membrane 65, driving the membrane surface to form uniform undulations. The airbags 71 are made of rubber, possessing good elasticity and sealing properties, and can deform stably during inflation and deflation. One end of each airbag 71 is connected to a pneumatic control component 72. The housing 721 within the pneumatic control component 72 has a hollow structure, with air outlets at both ends communicating with the airbags 71 or hoses 73. Springs 722 and elastic balls 723 are both placed inside the housing 721. The two ends of the spring 722 press against the inner wall of the housing 721 and the elastic ball 723, respectively. The surface of the ball 723, and the outer diameter of the elastic ball 723 is larger than the inner diameter of the air outlets at both ends of the housing 721, form a one-way sealing structure. When airflow enters from one side, it can push the elastic ball 723 to compress the spring 722 and open the corresponding air outlet to achieve airflow conduction. When the airflow stops or reverses, the spring 722 resets and pushes the elastic ball 723 to block the air outlet. The end of the air control component 72 away from the airbag 71 is connected to the end of the adjacent airbag 71 away from the air control component 72 through the hose 73, so that multiple airbags 71 form a series airflow channel through the hose 73, ensuring that the airflow can flow orderly between each airbag 71, forming one-by-one inflation. In addition, the housing 721 of the air control component 72 is fixedly installed on the rotating shaft 5 by the mounting rod 74.
[0033] Example 4: Please refer to Figures 1-8 The present invention provides a technical solution: a filter device for pharmaceutical equipment, wherein the end of the air control component 72 on the uppermost airbag 71 is connected to an air pump 8 through an extension tube 1, the extension tube 1 penetrates the filter tank body 1 and extends to the outside of the filter tank body 1, and the end of the lowermost airbag 71 away from the air control component 72 is connected to an air pump 9 through an extension tube 2, the extension tube 2 penetrates the filter tank body 1 and extends to the outside of the filter tank body 1.
[0034] In the auxiliary discharge mechanism 7, among the multiple air bladders 71, the uppermost air bladder 71 is connected to the end of the pneumatic control component 72 via an extension tube 1, which is connected to the suction pump 8. One end of the extension tube 1 is sealed to the air outlet of the pneumatic control component 72, and the other end penetrates the side wall of the filter tank 1, extends to the outside of the filter tank 1, and is connected to the suction port of the suction pump 8 to extract the gas from the air bladder 71, causing the air bladder 71 to contract. At this time, the filter membrane 65 is reset. Meanwhile, the lowermost air bladder 71, at the end furthest from the pneumatic control component 72, is connected to the blowing pump 9 via an extension tube 2. The extension tube 2 is connected to the airbag 71 with a sealed connection at one end, and the other end also penetrates the side wall of the filter tank 1, extends to the outside of the filter tank 1 and connects to the air outlet of the air pump 9. It is used to inject gas into the airbag 71, so that the airbag 71 is inflated and expands, pushing up the filter membrane 65 to form a wave. Through the coordinated work of the suction pump 8 and the air pump 9, the airflow can be controlled to flow unidirectionally in the channel of the series airbags 71. With the cooperation of the air control component 72, multiple airbags 71 are inflated and deflated one by one, thereby driving the filter membrane 65 to produce stable and uniform up and down fluctuations, improving the filtration effect and avoiding accumulation.
[0035] Based on the above embodiments, the following is the complete working principle of the above embodiments: In use, the biopharmaceutical liquid to be filtered is first poured into the feed hopper 2. The liquid first enters the mixing chamber 12 inside the filter tank 1, where it is initially mixed to ensure uniform composition. The mixed liquid then enters the stirring chamber 13 through the partition 121. The components in the stirring chamber 13 stir the liquid, further breaking up the agglomerated particles. Subsequently, under its own gravity, the liquid is transported through the leakage hole 1311 on the partition 131 to the starting end of the filter membrane 65 in the step-by-step discharge unit 6 in the filter chamber 14. In the step-by-step discharge unit 6, the inner guide plate 61 is fixed to the outer wall of the rotating shaft 5, and the outer guide plate 62 is fixed to the inner wall of the filter chamber 14. The two are clamped by the inner connecting membrane 63 and the outer connecting membrane 64 to form a complete filter layer. The liquid flows along the filter membrane 65. During flow, impurities are trapped, while qualified materials pass through the filter membrane 65. Simultaneously, the auxiliary discharge mechanism 7 at the bottom of the filter chamber 14 is activated, and the lowest airbag 71 is injected with gas through the air pump 9 connected to the extension tube 2. The gas passes through the series hoses 73 and each air control component 72, causing multiple airbags 71 to inflate one by one. The air control component 72 forms a one-way seal through the elastic ball 723 and spring 722, ensuring orderly airflow. The airbags 71 lift the filter membrane 65, and in conjunction with the elastic film in the movable groove 66 on the surface of the filter membrane 65 and the stretchable inner connecting membrane 63 and outer connecting membrane 64, the filter membrane 65 produces stable up-and-down fluctuations, preventing impurity accumulation. When contraction is required, the highest airbag 71 is evacuated through the suction pump 8 connected to the extension tube 1, the airbag 71 contracts, and the filter membrane 65 returns to its original position. The liquid that is not completely filtered or requires secondary purification in the filter chamber 14 enters the liquid recovery mechanism 3, is collected, and then passes through the recovery pipe 4. The material is conveyed back to the feed hopper 2 and re-enters the mixing chamber 12 to start a new round of filtration.
[0036] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.
[0037] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention.
Claims
1. A filtration device for pharmaceutical equipment, comprising a filter tank body (1), wherein the interior of the filter tank body (1) is provided with a driving chamber (11), a mixing chamber (12), a stirring chamber (13), and a filtering chamber (14) arranged sequentially from top to bottom, wherein the mixing chamber (12), the stirring chamber (13), and the filtering chamber (14) are separated by a partition plate one (121) and a partition plate two (131), characterized in that: A rotating shaft (5) is provided at the bottom center of the partition plate 2 (131). A step-by-step discharge unit (6) is provided inside the filter chamber (14) with the rotating shaft (5) as the axis. The step-by-step discharge unit (6) includes a filter membrane (65). Several movable grooves (66) are opened on the surface of the filter membrane (65). The movable grooves (66) are spaced equally apart. An elastic membrane is provided inside the movable grooves (66). An auxiliary discharge mechanism (7) is provided inside the filter chamber (14) at the bottom of the filter membrane (65). The auxiliary discharge mechanism (7) is used to lift the middle part of the filter membrane (65). The auxiliary discharge mechanism (7) includes a plurality of air bladders (71) disposed on the lower side of the filter membrane (65). Each air bladder (71) is located between every two movable slots (66). One end of each air bladder (71) is connected to a pneumatic control component (72). The end of the pneumatic control component (72) away from the air bladder (71) is connected to a flexible hose (73). The end of the flexible hose (73) away from the pneumatic control component (72) is connected to the end of the adjacent air bladder (71) away from the pneumatic control component (72). The pneumatic control assembly (72) includes a housing (721), both ends of which are provided with air outlets. A spring (722) is provided inside the pneumatic control assembly (72), and an elastic ball (723) is provided inside the pneumatic control assembly (72). The two ends of the spring (722) are pressed on the housing (721) and the elastic ball (723) respectively. The outer diameter of the elastic ball (723) is larger than the inner diameter of the air outlet. The housing (721) is mounted on the rotating shaft (5) by a mounting rod (74).
2. The filtration device for pharmaceutical equipment according to claim 1, characterized in that: The step-by-step discharge unit (6) also includes an inner guide plate (61) connected to the rotating shaft (5) and an outer guide plate (62) connected to the inner wall of the filter chamber (14). An inner connecting membrane (63) is installed at the end of the inner guide plate (61) opposite to the outer guide plate (62), and an outer connecting membrane (64) is installed at the end of the outer guide plate (62) opposite to the inner guide plate (61). The filter membrane (65) is disposed between the inner connecting membrane (63) and the outer connecting membrane (64).
3. The filtration device for pharmaceutical equipment according to claim 2, characterized in that: The inner connecting membrane (63) and the outer connecting membrane (64) are both detachably connected, and the inner connecting membrane (63) and the outer connecting membrane (64) are stretched as the filter membrane (65) fluctuates.
4. The filtration device for pharmaceutical equipment according to claim 1, characterized in that: All airbags (71) are made of rubber.
5. The filtration device for pharmaceutical equipment according to claim 1, characterized in that: The air control component (72) on the uppermost airbag (71) is connected to an air pump (8) via an extension tube. The extension tube passes through the filter tank body (1) and extends to the outside of the filter tank body (1).
6. The filtration device for pharmaceutical equipment according to claim 1, characterized in that: The bottommost airbag (71) is connected to an air pump (9) at one end away from the air control component (72) via an extension tube 2. The extension tube 2 passes through the filter tank body (1) and extends to the outside of the filter tank body (1).
7. The filtration device for pharmaceutical equipment according to claim 1, characterized in that: The surface of the second partition (131) is provided with a material leakage hole (1311) on the upper side of the starting end of the filter membrane (65).
8. The filtration device for pharmaceutical equipment according to claim 1, characterized in that: A partition plate (121) is provided on the filter tank body (1) at the mixing chamber (12). A liquid recovery mechanism (3) is provided on the rear side of the filter tank body (1). The liquid recovery mechanism (3) and the feed hopper (2) are connected by a recovery pipe (4).
Citation Information
Patent Citations
A tangential flow smart filtration device for biopharmaceutical applications
CN114602239B
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