Analgesic administration modulation system

Abstract

The present application relates to a kind of analgesic administration control system.The system includes handgrip, analgesic drug delivery device connected with handgrip and information processing unit.The system is also provided with uterine contraction detection module and electroencephalogram detection module.When receiving the request signal sent by patient request unit, information processing unit generates the drug injection amount corresponding to brain information based on the brain information presented by electroencephalogram detection module, wherein, limited to the original bioelectric potential signal related to uterine muscle contraction presented by uterine contraction detection module, the drug injection amount adjusted based on brain information is adjusted within the partition range matched with the uterine contraction rhythm reflected by original bioelectric potential signal.The present application generates injection control signal containing injection type and injection amount with uterine contraction state as the objective reference factor of puerpera's body, and adjusts the point value within injection amount range based on the subjective factor taking puerpera's stress as the main reference information.

Description

Technical Field

[0001] This invention relates to the field of drug infusion pump technology, and more particularly to an analgesic drug delivery control system. Background Technology

[0002] Each woman's physiological characteristics and pain tolerance vary significantly, making it difficult to effectively manage pain using traditional analgesia or medication systems. Childbirth is a complex and dynamic process, and the woman's needs change throughout. As labor progresses, the woman's drug tolerance may also change. For example, some women may respond well to low doses of medication during the first stage of labor, but during the second stage, as contractions become stronger, the same dose may no longer be sufficient. Existing analgesia systems often cannot monitor and adapt to these changes in tolerance in real time, resulting in unstable analgesic effects. For example, Siyoum, M., & Mekonnen, S., in their 2019 paper "Labor pain control and associated factors among women who gave birth at Leku primary hospital, southern Ethiopia" (see BMC research notes, 12(1), 619), explored the perception and control of labor pain among different women. This study found individual differences in the control of labor pain and also found that the perceived control of labor pain is affected by the progress of labor. Some women may experience intense pain from even mild contractions, while others may only show significant pain with more intense contractions. This individual difference is not only reflected in pain perception but also involves other physiological parameters such as heart rate, blood pressure, and respiratory rate. Kuhn, JC, Falk, RS., & Langesaeter, E., in their 2017 paper "Haemodynamic changes during labour: continuous minimally invasive monitoring in 20 healthy parturients" (International Journal of Obstetric Anesthesia, 31, 74-83), monitored hemodynamics in women during labor. They found that hemodynamic pressure was higher during contractions, especially in the second stage of labor, and that cardiac output, stroke volume, heart rate, systolic blood pressure, and systemic vascular resistance all fluctuated to some extent.Furthermore, Wu, Y., Chu, Y., Zhao, X., Wang, X., Chen, L., Duan, R., Li, Y., & Liu, X., in their 2024 paper "The Chinese version of rating scale of pain expression during childbirth" (see (ESVADOPA): reliability and validity assessment. BMC Nursing, 23(1), 520.), pointed out that differences in pain assessment methods can affect an individual's response to pain, and that there are differences between subjective and objective pain assessments. Due to the complex subjective nature of pain, pain measurement, especially labor pain measurement, is more challenging and specific than other vital sign measurements. US20140316371A1 discloses a computer-implemented method for controlling the dispensing of bioactive agents. This technical solution relates to controlling the dispensing of bioactive agents, particularly using a computer-implemented method for labor pain management. The method includes: initiating intermittent dosing of a bioactive agent at a first background dose rate; and adjusting the background dose rate according to the number of input signals received from a signaling device. While this technology can dynamically adjust drug dosage according to the patient's needs, it relies on the patient indicating pain needs through a signaling device (such as a button). This self-reporting method can be affected by the patient's communication ability, cognitive state, and pain tolerance, leading to inaccurate input signals.

[0003] US20070233203A1 discloses an obstetric analgesia system that utilizes EHG signals and other monitoring methods (such as fetal heart rate monitoring, uterine contraction monitoring, etc.) to predict the onset of uterine contractions, thereby automatically or through patient-controlled administration of analgesics before contractions cause pain. However, the assessment of pain stress related to the implementation or delivery of pain management in this system is relatively subjective, leading to inaccurate input judgment signals. For example, CN111671505A also discloses an intelligent injection system and method that adjusts the injection volume level based on cervical dilation and pain level. This application uses the VAS score to assess the pain perception of parturient women. The VAS scoring system (pain level rating scale) uses visual analogues to assess the severity of pain. The scoring system typically uses a scale divided into 10 equal parts, with a scoring range from 0 to 10, where 0 represents no pain, 1-3 represents mild pain, 4-6 represents moderate pain, and 7-10 represents severe pain. Patients mark the location corresponding to their perceived pain level on this scale. However, due to the lack of a control group, pregnant women often cannot clearly distinguish the specific pain level when the pain level reaches level 5 or above, and may randomly select a pain level or report a high pain level.

[0004] US20070299389A1 provides a system and method for optimizing the control of patient-controlled analgesia (PCA) and patient-controlled epidural analgesia (PCEA) systems. Because the threshold values ​​of physiological parameters vary from person to person, this system cannot adapt to the physiological and tolerance differences of different individuals, especially for women in labor, where it clearly cannot meet the requirements for adjusting to changes in bodily changes. CN115006678A discloses a method and device for labor analgesia with adjustable drug concentration. The device includes a handheld pressure sensing component, a uterine contraction monitoring component, a sound acquisition component, a control component, and an injection component. This technical solution measures the degree of pain in the woman in labor using a handheld pressure sensing component and a sound acquisition component placed in her hand, detects uterine contraction pressure using a uterine contraction monitoring component placed in her abdomen, and stores different types of drugs in drug reservoirs. Based on the measurement results, the valves on each drug reservoir are controlled to open or close, thereby obtaining mixed drugs of different concentrations. This technical solution can adjust the concentration and infusion volume of the mixed medication based on the mother's pain level and uterine contraction pressure, thereby improving the analgesic effect during labor. However, the pressure and / or decibel data detection involved in this solution are intended to determine different pain levels, with different pain levels corresponding to different preferred medications. This setup only determines a single dosing regimen, and the different detection data are merely for the purpose of obtaining that single regimen. Once the dosing regimen is determined, if the mother's detection data changes and adjustments to the preset regimen are needed, a new dosing regimen must be determined by combining multiple different detection data. This makes it impossible to achieve real-time updates and adjustments to the dosing regimen to match the mother's actual physiological pain levels.

[0005] Existing pain management systems typically employ static or semi-static dosing protocols, failing to respond in real-time to dynamic changes. For example, some systems may adjust drug dosage based on preset time intervals or fixed contraction frequencies, but this does not accurately reflect the mother's actual needs. Therefore, during periods of particularly intense contractions or significant emotional fluctuation, mothers may experience insufficient pain relief, impacting their labor experience. Furthermore, existing technologies fail to provide personalized pain management plans, unable to adapt to each mother's physiological characteristics and pain tolerance. For instance, some systems may set the same initial dose for all mothers, ignoring individual differences. Summary of the Invention

[0006] In view of these existing technologies, the object of the present invention is to determine the dynamic changes in the pharmacological needs of women during childbirth.

[0007] The present invention also aims to provide an analgesic drug delivery system for the labor process, which obtains information on the uterine contraction status and emotional changes of the parturient to obtain differences in the physiological characteristics and pain tolerance of the parturient, thereby providing personalized drug delivery strategies for different parturients.

[0008] Another objective of this invention is to integrate physiological index monitoring with a comprehensive reflection of pain and stress levels to assess the mother's medication needs, thereby avoiding overly subjective preconditions for drug administration. Specifically, an initial drug injection dose is generated based on brain information and matched accordingly, and then dynamically adjusted based on the presented original bioelectrical potential signal.

[0009] Another object of the present invention is to provide a grip strength device that identifies the request signals sent by a postpartum woman while she is awake, thereby obtaining the grip strength of the postpartum woman as the intensity of uterine contractions increases, and thus reflecting the postpartum woman's true need for medication.

[0010] This application provides an analgesic drug delivery control system. The system includes a gripper with a patient request unit, an analgesic drug delivery device connected to the gripper that delivers the drug to the mother when the patient request unit transmits a request signal, and an information processing unit that generates a signal to control the injection volume of the analgesic drug delivery device based on received information related to the mother.

[0011] The system is also equipped with a uterine contraction detection module to collect data reflecting the rhythm of pain in the mother and an electroencephalogram (EEG) signal detection module to collect data reflecting the mother's pain status. When a request signal is received from the patient request unit, the information processing unit generates a drug injection dosage corresponding to the brain information presented by the EEG signal detection module. The drug injection dosage, which is adjusted based on the brain information, is limited by the original bioelectric potential signal related to uterine muscle contraction presented by the uterine contraction detection module. The dosage is adjusted within a range that matches the uterine contraction rhythm reflected by the original bioelectric potential signal.

[0012] Compared with the prior art, the present invention can generate an initial drug injection dose matching the brain information presented by the electroencephalogram (EEG) signal detection module, and can simultaneously dynamically adjust the initial drug injection dose based on the original bioelectric potential signal related to uterine muscle contraction presented by the uterine contraction detection module. Based on the above distinguishing technical features, the problems to be solved by the present invention can include: how to dynamically adjust the injection dose of analgesic drugs according to different stages of the uterine contraction rhythm during labor, so as to finely adjust the analgesic drug dosage in accordance with the dynamic changes in the pain experienced by the mother. Specifically, the rhythm of uterine contractions during labor includes intermittent periods and peak periods, and the intensity of the contraction response gradually increases with the approach of labor, thereby causing the patient to experience different degrees of pain. Therefore, the injection dose of analgesic drugs should also be dynamically adjusted according to the patient's labor progress. The beneficial effects of this technical solution are as follows:

[0013] The prior art intelligent injection system disclosed in publication number CN111671505A uses pain level and cervical dilation size fed back by a feedback parameter receiving module to classify injection modes and parameters. Unlike the prior art intelligent injection system, this application uses uterine contraction status as an objective reference factor for the mother's body to generate an injection control signal containing injection type and volume, and adjusts point values ​​within the injection volume range based on subjective factors, with the mother's stress as the primary reference information.

[0014] Objective factors of the mother's body are standard values ​​that reflect the mother's pain state. Changes in this state can be predicted by medical staff, and corresponding analgesia measures can be given based on the changes in this process. Therefore, this application reflects the pain rhythm based on the mother's uterine contraction rhythm, and at the same time enables the analgesic drug delivery device to provide the corresponding drug delivery to the mother in accordance with the preset rules along with the rhythm.

[0015] Furthermore, the mother's subjective factors (or pain perception) vary due to individual differences. When a mother requests analgesia based on pain, individuals experiencing more severe pain require higher doses to alleviate their pain. Patent application CN111671505A discloses a VAS scoring method for adjusting drug injection patterns. However, the VAS scoring method requires the mother to assess her perception while experiencing pain, which cannot eliminate the bias caused by subjectivity. In particular, mothers in a progesterone-stimulated pain state have lower mental clarity, resulting in lower reliability of their scores. This makes it difficult for the VAS scoring method to effectively adjust the device to a dosage that relieves the mother's pain, or to excessively increase the dosage in a single instance (because a large dose lowers the baseline pain level, the mother will only need a higher dosage to achieve a perceived change in pain relief, which will reduce the experience of painless childbirth for mothers whose pain intensifies with later uterine contractions).

[0016] Furthermore, unlike the assessment parameter of cervical dilation disclosed in patent application CN111671505A, this application uses the detection information of uterine contraction rhythm as the basis for assessing the type and dosage of analgesic drugs. Since the cervix dilates gradually to over ten centimeters over a relatively long period (e.g., 6-18 hours), and the initial changes are relatively small, using cervical dilation as a reference data point reduces the flexibility of the assessment, resulting in a smaller range of changes in the assessment results and failing to match the actual changes in the mother's pain. This application uses the mother's uterine contraction rhythm as a reference indicator, which is also the main basis for directly reflecting the rhythm of the mother's pain. With changes in the uterine contraction rhythm, the type and dosage of analgesic drugs can be adjusted during the peak or interval of each or several contractions. In particular, the pain during the interval between contractions is less than that during the peak of the contraction; therefore, the timing of drug injection affects the mother's pain perception.

[0017] According to a preferred embodiment, the brain information includes at least brain signals whose waveform curves, acquired by the brain signal detection electrodes of the brain signal detection module, conform to brain electrical characteristics that characterize brain activity. The time and frequency domains of the brain electrical signals characterizing brain activity are used to match the drug injection dosage adjusted based on brain information in a manner that characterizes the mother's stress state.

[0018] According to a preferred embodiment, the information processing unit is configured as follows:

[0019] Based on the original bioelectric potential signals related to uterine muscle contraction collected by the uterine contraction detection module, a regular waveform curve is formed. When the regular waveform curve exhibits characteristics consistent with the peak period of uterine contraction, medication is administered to the mother within a preset injection volume range. The preset injection volume range is driven by the generation time node of the regular waveform curve that matches the peak period of uterine contraction, increasing / decreasing the injection volume according to the preset value. Existing technologies already exist for detecting uterine contraction data to assess the mother's condition. For example, CN113018618A discloses a device for auxiliary anesthesia in clinical anesthesiology, including respiratory, blood oxygen, fetal movement, and uterine contraction pressure sensors to monitor the physiological state of the mother and fetus. The main control unit receives all signals and analyzes them to determine the mother's condition. Based on different conditions, the main control unit controls the ventilator to perform different ventilation modes, deliver anesthetic gas, inject oxytocin, or enter the anesthetic drug preparation state. This technical solution calculates the uterine contraction pressure value using the uterine contraction pressure signal acquired by the uterine contraction pressure sensor and executes corresponding treatment plan adjustments by monitoring changes in the uterine contraction pressure signal. However, the uterine contraction pressure data obtained by this technical solution is limited to controlling the operation mode of a single ventilator and cannot be superimposed on other detection data for fine-tuning of analgesic drug injection dosage. Furthermore, the uterine contraction pressure values ​​detected in this technical solution can only reflect node parameters in the current state and cannot be used to achieve continuous, periodic treatment plan adjustments. Therefore, it is impossible to dynamically adjust the analgesic drug injection dosage based on the patient's physiological state data at different uterine contraction stages. Compared with the above-mentioned prior art, the information processing unit of this invention can form a regular waveform curve based on the raw bioelectric potential signal collected by the uterine contraction detection module, and can increase the injection dosage at the generation time node of the regular waveform curve that conforms to the characteristics of the uterine contraction peak period. Based on the above distinguishing technical features, the problem to be solved by this invention can include: how to dynamically adjust the analgesic drug injection dosage according to the different uterine contraction peak period characteristics of the patient. Specifically, the cyclical drug administration in this application is divided into an initial dose and a mixed drug. When the mother enters a contraction state and experiences her first regular contraction, the initial dose is injected during the peak of the contraction. During the second and subsequent regular contractions, the mixed drug is injected during the peak of the contraction. The injection volume increases by a preset amount as the number of contractions increases, thereby achieving dynamic matching between the analgesic drug injection volume and the mother's contraction state to reduce her pain.

[0020] According to a preferred embodiment, the analgesic drug delivery device includes a first drug container and a second drug container driven by a drive module, wherein the first drug container and the second drug container respectively hold different types of drugs.

[0021] According to a preferred embodiment, when a regular waveform curve formed by the original bioelectric potential signal related to uterine muscle contraction, collected by the contraction detection module and conforming to the characteristics of the peak period of uterine contraction, first appears, the information processing unit controls the drive module of the analgesic drug delivery device to drive the second drug box to inject the first dose of drug into the parturient at a preset content. In this process, controlled by the request signal sent by the patient request unit and the brain information characterizing the parturient's stress state, the information processing unit sends a drug delivery signal to the analgesic drug delivery device with an adjusted injection volume, controlling the second drug box and the first drug box to supply the drug at a preset ratio.

[0022] Preferably, the first and second drug containers of the analgesic drug delivery device contain ropivacaine and sufentanil, respectively. When a regular waveform curve, based on the original bioelectric potential signal related to uterine muscle contraction collected by the uterine contraction detection module and conforming to the characteristics of the peak uterine contraction period, first appears, the information processing unit controls the drive module of the analgesic drug delivery device to drive the second drug container containing sufentanil to inject the first dose of medication into the parturient at a preset dosage. Controlled by the request signal sent by the patient request unit and brain information characterizing the parturient's stress state, the information processing unit sends a drug delivery signal to the analgesic drug delivery device with an adjusted injection volume, controlling the second drug container containing sufentanil and the first drug container containing ropivacaine to be supplied at a preset ratio.

[0023] According to a preferred embodiment, based on the regular waveform curve formed by the original bioelectric potential signal related to uterine muscle contraction collected by the contraction detection module that conforms to the characteristics of the peak period of uterine contraction, which is not the first occurrence, the information processing unit controls the drive module of the analgesic drug delivery device to drive the second drug box and the first drug box to inject the drug in the uterine contraction cycle into the parturient at a preset ratio. The injection volume of the drug mixture generated by the second drug box and the first drug box at the preset ratio is driven by the generation time node of the regular waveform curve that conforms to the characteristics of the peak period of uterine contraction and increases according to a preset increment value.

[0024] Preferably, the information processing unit is configured such that the regular waveform curve formed by the original bioelectric potential signal related to uterine muscle contraction collected by the uterine contraction detection module, which conforms to the characteristics of the peak period of uterine contraction, is not the first occurrence.

[0025] The drive module that controls the analgesic drug delivery device drives the second drug tank containing sufentanil and the first drug tank containing ropivacaine to inject the drugs into the parturient woman during the uterine contraction cycle at a preset ratio.

[0026] According to a preferred embodiment, the information processing unit is configured such that the regular waveform curve formed by the original bioelectric potential signal related to uterine muscle contraction, collected by the uterine contraction detection module and conforming to the characteristics of the peak period of uterine contractions, does not appear for the first time.

[0027] Controlled by the request signal sent by the patient request unit and brain information representing the mother's stress state, the injection volume of the first or second drug box is increased according to a preset increment value.

[0028] Preferably, the information processing unit is configured such that the regular waveform curve formed by the original bioelectric potential signal related to uterine muscle contraction collected by the uterine contraction detection module, which conforms to the characteristics of the peak period of uterine contraction, is not the first occurrence.

[0029] Controlled by the request signal sent by the patient request unit and brain information representing the mother's stress state, the injection volume of the first or second drug box is increased according to a preset increment value.

[0030] According to a preferred embodiment, the grip strengthener includes an elastic outer shell, at least two elastic support rods intersecting inside the elastic outer shell, and a pressure sensor disposed at the center of the intersection of the elastic support rods and capable of sensing the pressure value of the corresponding elastic support rod. When the pressure value transmitted by the pressure sensor exceeds a preset threshold, a spring compressor disposed at one end of the elastic support rod for adjusting the spring compression range of the elastic support rod is decompressed under the control of the information processing unit, so that the mother's fingers extend as the elastic outer shell expands.

[0031] According to a preferred embodiment, the patient request unit includes a vibration sensor to identify tapping behavior sent by the mother while she is awake, for sending a request signal to the analgesic drug delivery device.

[0032] According to a preferred embodiment, the surface of the elastic shell is provided with at least one finger sleeve, wherein a vibration sensor capable of sensing the tapping behavior generated in the area corresponding to the at least one finger sleeve is provided. Attached Figure Description

[0033] Figure 1 A diagram illustrating the usage state of a pregnant woman in a lying position, as provided by this invention.

[0034] Figure 2 This invention provides a diagram illustrating the usage state of a pregnant woman sitting and supporting herself against a wall.

[0035] Figure 3 Functional structure diagram of the guide module provided by the present invention;

[0036] Figure 4 A functional structure diagram of the guide module under another embodiment of the present invention;

[0037] Figure 5 A perspective view of the grip strengthener provided by the present invention;

[0038] Figure 6A perspective view of another embodiment of the grip strengthener provided by the present invention;

[0039] Figure 7 Internal structure diagram of the grip strengthener provided by the present invention;

[0040] Figure 8 The system flowchart provided for this invention;

[0041] Figure 9 This is a schematic diagram of the analgesia method provided by the present invention.

[0042] List of reference numerals

[0043] 100: Analgesic drug delivery device; 110: Drive module; 120: First drug container; 130: Second drug container;

[0044] 200: Grip strength trainer; 210: Patient request unit; 211: Vibration sensor; 220: Pressure component; 221: Elastic support rod; 222: Spring compressor; 223: Pressure sensor; 230: Emotion information acquisition unit; 231: Voice recognizer; 232: Player; 240: Elastic shell; 250: Rebound wrist strap; 251: Button; 252: Ring; 260: Finger sleeve; 300: EEG signal detection module; 310: EEG detection electrode; 320: First filter amplification circuit; 400: Uterine contraction detection module; 410: Potential signal acquisition unit; 500: Information processing unit; 600: Physiological parameter detection module. Detailed Implementation

[0045] The following is a detailed explanation with reference to the accompanying drawings.

[0046] In the description of this invention, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. It should be noted that, unless otherwise explicitly specified and limited, the terms "installed," "equipped with," and "connected," etc., should be interpreted broadly. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components. "Several" means two or more, unless otherwise explicitly and specifically defined. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0047] Example 1

[0048] This embodiment provides a system for sedating the pain of labor caused by uterine contractions in mothers during childbirth by administering different dosages and types of drugs to reduce the pain experienced by the mother.

[0049] This application relates to an analgesic drug delivery regulation system. Figure 3 , 4 A functional structure diagram of the system is shown. In this application, the grip strength device 200, the electroencephalogram (EEG) signal detection module 300, the analgesic drug delivery device 100, and the uterine contraction detection module 400 can establish communication connections via wireless networks (e.g., Bluetooth, WIFI, Zigbee, etc.), such as data, signals, and / or control signals.

[0050] Another aspect of this application relates to an analgesic drug delivery device 100. The analgesic drug delivery device 100 is capable of establishing a drug delivery relationship with the parturient through means such as puncture. Preferably, the analgesic drug delivery device 100 is capable of delivering at least one anesthetic drug to the parturient through an epidural catheter placed in the intervertebral space.

[0051] Specifically, such as Figure 1 and 3 As shown, the analgesic drug delivery device 100 includes a first drug container 120, a second drug container 130, a communication module, and a drive module 110. The communication module can receive drug delivery signals sent by the information processing unit 500. The drive module 110 can simultaneously drive the flow of drug in the first drug container 120 and the second drug container 130, or it can drive the flow of drug in either the first drug container 120 or the second drug container 130 independently, for example, a PCA pump (analgesic pump).

[0052] Preferably, the first medicine box 120 and the second medicine box 130 contain different types of drugs, for example, the first medicine box 120 contains ropivacaine and the second medicine box 130 contains sufentanil.

[0053] This application, in another aspect, relates to a uterine contraction detection module 400. The uterine contraction detection module 400 includes a potential signal acquisition unit 410 and a power supply unit for supplying power to the potential signal acquisition unit 410. Preferably, as... Figure 1 , Figure 2 As shown, during painless childbirth, the potential signal acquisition unit 410 is attached to the mother's upper abdomen in the form of electrode pads to collect electromyographic signals of the uterus, such as EMG. The uterine contraction detection module 400 can transmit the collected signals to the information processing unit 500 to obtain the uterine fluctuation state during contractions.

[0054] Specifically, the waveform curves formed by the signals representing uterine contractions acquired by the potential signal acquisition unit 410 include both regular and irregular waveform curves. The system involved in this application can distinguish whether a pregnant woman has entered the labor state based on the regularity of the waveform curves, that is, to identify the authenticity of uterine contractions. Since false labor contractions are a phenomenon of false labor, in current pregnancy and childbirth knowledge, in order to avoid the pregnant woman losing her perception of real labor contractions, the injection of analgesics, especially epidural analgesia, should be avoided as much as possible. Since pregnant women before labor (especially first-time mothers) may experience false labor contractions before real labor contractions occur, it is a necessary step to determine the timing of the first injection of analgesics by analyzing the waveform curves.

[0055] The rhythm of uterine contractions includes intervals and peak periods, and the intensity of the contractions gradually increases as labor progresses. Therefore, the dosage of analgesics should not be constant.

[0056] In this application, the information processing unit 500 is driven by the generation time node of a regular waveform curve that conforms to the characteristics of the peak period of uterine contractions. As the uterine contraction progresses, the injection volume increases. Preferably, the injection volume increases by a preset amount each time a regular waveform curve conforming to the characteristics of the peak period of uterine contractions is generated. Preferably, since the injection volume of different drugs is different, the increase in injection volume (preset increase value) involved in this application may include the increase in the injection volume of a single drug.

[0057] At the same time, the rhythm of uterine contractions, namely the intervals and peak periods, also needs to be monitored. Administration methods for labor analgesia generally include cyclical administration and demand-based administration. Cyclic administration, based on the rhythm of uterine contractions, involves administering medication to the mother at the peak of contractions according to a pre-set dosage and type of drug. Because uterine contractions exhibit a regular pattern of gradually increasing peak values, this type of administration is called cyclical administration.

[0058] In this application, based on years of experience in obstetric anesthesia, the applicant divides cyclical drug administration into an initial dose and a mixed drug. When the mother experiences her first regular uterine contraction, she is injected with 5 μg of sufentanil at the peak of the contraction. Simultaneously, an injection volume of 0.3 μg / mL sufentanil + 0.1% ropivacaine is provided to deliver the drug to the mother based on the injection volume determined by the information processing unit 500 when the mother requests an injection. During the second and subsequent regular uterine contractions, the mother is injected with a drug mixture of 0.3 μg / mL sufentanil + 0.1% ropivacaine at the peak of the contraction. The injection volume increases by a preset amount with each contraction, and a single drug delivery is provided to the mother based on the injection volume determined by the information processing unit 500 when the mother requests an injection.

[0059] It is important to note that, in order to ensure the stability of the blood concentration of anesthetic drugs in the mother, the injection volume of sufentanil + 0.1% ropivacaine at a rate of 0.3 μg / mL every 20 to 30 minutes from the onset of regular uterine contractions should not exceed 5 mL.

[0060] This application, in another aspect, relates to an electroencephalogram (EEG) signal detection module 300. The EEG signal detection module 300 includes EEG detection electrodes 310, a first filtering and amplification circuit 320, and a power supply unit, such as... Figure 3 , 4 As shown. The EEG signal detection module 300 can be configured as a wearable device, transmitting signals wirelessly to the information processing unit 500. When the mother enters labor, the EEG signal detection module 300 worn on her head does not interfere with the medical staff's assistance during childbirth, nor does it affect the mother's actions when getting out of bed to alleviate contraction pain, such as... Figure 2 As shown. When the EEG detection electrode 310 acquires brainwave signals, such as EEG, the EEG signal detection module 300 sends the acquired signals to the information processing unit 500 after filtering and adjustment by the first filtering and amplification circuit 320, in order to generate information for judging the mother's stress state. Preferably, the EEG signal detection module 300 can be an EEG device disclosed in CN107690308B, a multi-channel portable EEG device (such as Emotiv EPOC X), etc.

[0061] Another aspect of this application relates to an information processing unit 500. The information processing unit 500 can be configured as an integrated device, integrated into the hand gripper 200 or the analgesic drug delivery device 100, or it can be configured as a stand-alone device. Preferably, the information processing unit 500 can be a smartphone, smartwatch or other wearable device, tablet computer, computer, cloud server, or other intelligent device with a CPU and a communication module. The CPU receives detection signals from the electroencephalogram (EEG) signal detection module 300, the uterine contraction detection module 400, the hand gripper 200, or the physiological parameter detection module 600 with blood oxygen, blood pressure, and heart rate detection functions via the communication module, and converts the detection signals into processable data for further generating signals to control the analgesic drug delivery device 100.

[0062] Another aspect of this application relates to a hand gripper 200. The hand gripper 200 includes a resilient housing 240 and a patient request unit 210, a power supply unit, and a pressure assembly 220.

[0063] Specifically, such as Figure 7As shown, the pressure assembly 220 includes at least two intersecting elastic support rods 221 inside the elastic housing 240, and a pressure sensor 223 disposed at the center of the intersection of the elastic support rods 221 and capable of sensing the pressure value of the corresponding elastic support rod 221. The elastic support rods 221 are connected to the elastic housing 240 via a spring compressor 222. Based on a preset pressure value, the spring compressor 222 adjusts the elastic force of the elastic support rods 221 so that the grip strengthener 200 matches the grip strength of the postpartum woman.

[0064] As the intensity of uterine contractions (or pain) increases, the mother's grip strength gradually increases. When the pressure value transmitted by the pressure sensor 223 exceeds a preset threshold, the spring compressor 222, located at one end of the elastic support rod 221 to adjust the spring compression range of the elastic support rod 221, is controlled by the information processing unit 500 to decompress the spring. The spring is sleeved on the elastic support rod 221. After the spring is decompressed, it increases the length of the elastic support rod 221, that is, the decompressed spring elastic shell 240 expands, and the bending degree of the mother's fingers holding the grip strengthener 200 in a gripping posture decreases. At this time, the mother's fingers extend as the elastic shell 240 expands.

[0065] The hand gripper 200 is also equipped with a vibration sensor 211. Because postpartum women in pain cannot control themselves, their hands will unconsciously apply pressure to objects in their palms. Existing analgesic pump controllers are basically designed as thumb-pressing devices, which also leads to postpartum women in pain unconsciously pressing repeatedly, causing the analgesic pump to deliver analgesic drugs to the postpartum woman at its maximum output, and the system's drug adjustment based on the postpartum woman's condition is not very effective. Therefore, this application sets the patient request unit 210 as a component with a tapping signal transmission mode, that is, the patient request unit 210 includes a vibration sensor 211 to identify tapping behavior sent by the postpartum woman in a conscious state to send a request signal to the analgesic drug delivery device 100, such as... Figure 1 and Figure 6 As shown.

[0066] In order to accurately locate the impact area, the elastic shell 240 of this application has one of the following two structures added to its surface.

[0067] The surface of the elastic outer shell 240 is provided with at least one finger sleeve 260, wherein the area corresponding to the at least one finger sleeve 260 is provided with a vibration sensor 211 capable of sensing the tapping behavior generated in the corresponding area, such as... Figure 5 As shown.

[0068] A spring-loaded wrist strap 250 is provided on the surface of the elastic outer shell 240. One end of the spring-loaded wrist strap 250 has an adjustment unit including a spring and a locking assembly, and the other end has a loop 252 that fits around the mother's wrist. Preferably, the structure of the adjustment unit can be the same as the telescopic structure of a retractable traction rope, or the same as the automatic telescopic structure of a measuring tape. When the mother needs to get out of bed to relieve uterine contraction pain, she can release the hand gripper 200, leaving it suspended in the air. Figure 2 As shown, the mother can use her palms to support herself against the wall to complete the relevant movements.

[0069] After returning to bed, pressing button 251 causes the grip strengthener 200 to spring back into the hand, restoring control of the analgesic drug delivery device 100. Preferably, button 251 can be located on ring 252 or on the surface of resilient housing 240.

[0070] According to a preferred embodiment, the analgesia regulation system involved in this application is located in the hospital's clinical information system and is able to interface with the hospital information system.

[0071] Specifically, when a pregnant woman is admitted to the hospital in an emergency or is determined to be in labor in a ward, based on the occurrence of the pregnant woman entering the labor room, the obstetrician's smart device (such as the obstetrician's mobile phone) in the clinical information system is connected to the analgesia regulation system. The obstetrician can remotely send instructions to the information processing unit 500 through the communication module in the obstetrician's smart device before arriving at the labor room but before the midwife has arrived. Based on the pregnant woman's medical history, the initial dosage of analgesic drug delivery device 100 in the labor room is adjusted.

[0072] During this process, since the use of analgesics is monitored (e.g., dosage monitoring, and the need to recycle empty analgesic bottles), the information processing unit 500 can record the dosage of analgesics used by the analgesic delivery device 100 and send it to the hospital information system to verify whether the amount of analgesics recycled is correct.

[0073] Example 2

[0074] This embodiment provides a method for regulating analgesic drug administration to women under stress. In this embodiment, a CPU integrated into a hand gripper 200 is used as an example. Figure 3 As shown, except for the different control method of the information processing unit 500 on the analgesic drug delivery device 100, the other hardware is the same as in the previous embodiment.

[0075] The potential signal acquisition unit 410 of the contraction detection module 400 acquires the raw bioelectric potential signal of the parturient woman from her abdomen. After receiving the signal sent by the contraction detection module 400, the information processing unit 500 of the hand gripper 200 analyzes the parturient woman's contraction state using a model disclosed in, for example, CN109875556B. When the waveform curve formed by the parturient woman's raw bioelectric potential signal first shows regular fluctuations, the information processing unit 500 of the hand gripper 200 generates an instruction to control the analgesic drug delivery device 100 to inject the parturient woman with 5 μg of sufentanil during the peak of the contraction. Subsequently, during the contraction period of this contraction or several cycles, when the parturient woman taps the hand gripper 200, causing the vibration sensor 211 of the hand gripper 200 to generate a request signal sent to the information processing unit 500, the information processing unit 500 analyzes the calibration index α of the electroencephalogram (EEG) signal acquired by the EEG signal detection module 300, such as... Figure 8 As shown. The scaling index contains data characterizing the amplitude of changes in EEG signals to indicate changes in the mother's emotional state. For example, the scaling index includes the time domain or frequency domain of the EEG signal. Time domain features refer to extracting information from the time series of the EEG signal. Common time domain features include: mean amplitude, variance, slope, peak time, maximum and minimum values, etc. Frequency domain features refer to extracting frequency characteristic information from the EEG signal through frequency analysis. Common frequency domain features include: wave frequency, power spectral density, energy spectrum, absolute / relative normalized power, spectral bandwidth, etc.

[0076] Taking the frequency of EEG signals as an example, when the scaling index α is lower than a preset threshold, the information processing unit 500 controls the analgesic drug delivery device 100 to provide the mother with a first preset injection dose of 0.3 μg / mL sufentanil + 0.1% ropivacaine.

[0077] When the calibration index α is higher than the preset threshold, the information processing unit 500 controls the analgesic drug delivery device 100 to provide the parturient with a second preset injection dose of 0.3 μg / mL sufentanil + 0.1% ropivacaine.

[0078] Preferably, the first preset injection volume is less than the second preset injection volume.

[0079] Compared to the VAS score, which relies on the mother's own feelings, this application uses objective parameters (such as physiological parameters) to assess the mother's subjective feelings (pain perception), thus avoiding the situation where the mother cannot distinguish the specific pain level when the pain level reaches 5 or above due to the lack of a control group.

[0080] Example 3

[0081] This embodiment provides an analgesic method based on the system provided in Embodiment 1. The analgesic method based on the analgesic drug delivery regulation system includes the following steps.

[0082] Medical staff connect the analgesia administration control system to the hospital's Clinical Information System (CIS) and input the mother's basic information (such as age, weight, height, pregnancy history, etc.). The medical staff attach the EEG signal detection module 300 to the mother, ensuring the electrodes are properly positioned on her head to collect accurate brainwave signals. The medical staff attach the potential signal acquisition unit 410 of the uterine contraction detection module 400 to the mother's abdomen to ensure real-time monitoring of uterine muscle contractions. The medical staff give the mother a hand gripper 200 and instruct her on how to use the patient request unit 210. The hand gripper 200 is worn by the mother, ensuring she can send a request signal at any time when she feels pain. The uterine contraction detection module 400 begins real-time acquisition of raw bioelectric potential signals reflecting uterine muscle contractions and transmits the data to the information processing unit 500. The information processing unit 500 analyzes the acquired waveform curves to determine whether the contractions are regular. The analysis of whether uterine contractions are regular by the information processing unit 500 includes: calculating the frequency of contractions to determine if there is a stable periodic change; assessing the intensity of each contraction to observe if there is a gradually increasing trend; measuring the duration of each contraction to determine if it is gradually prolonging; and assessing the symmetry of the waveform to determine if there is a uniform upward and downward trend. If the information processing unit 500 determines that the waveform curve is irregular, the system identifies it as a false contraction and continues monitoring. At this time, the system will not initiate the analgesic drug injection procedure. If the information processing unit 500 determines that the waveform curve is regular, the system identifies it as a true contraction and proceeds to the next step. When the peak characteristics of the contraction reappear, the information processing unit 500 obtains the regular waveform curve and determines the time node of this contraction. The system records these time nodes and provides a time frame for subsequent drug delivery, making the delivery more targeted. The analgesia method of this embodiment is as follows: Figure 9 As shown.

[0083] When the system first identifies the peak of true uterine contractions, the information processing unit 500 generates a control signal to control the analgesic drug delivery device 100 to inject the first dose of medication into the mother. The first dose typically contains 5 μg of sufentanil to quickly relieve the mother's initial pain. The medication is delivered to the mother through an epidural catheter. The information processing unit 500 records the time of the first contraction and begins monitoring the frequency and intensity of subsequent contractions. In this embodiment, the analgesic drugs may also include fentanyl, bupivacaine (suitable for situations requiring prolonged analgesia, such as the second stage of labor or cesarean section), lidocaine, tetracaine, tramadol, nalbuphine, etc., and the dosage may be adjusted based on the actual clinical situation, the doctor's advice, and the mother's feedback.

[0084] In this embodiment, the analgesic drug delivery device 100 includes a drive module 110, a first drug container 120, and a second drug container 130. The drive module 110 is the core component controlling drug delivery. The first drug container 120 is used to store one analgesic drug (such as bupivacaine). The second drug container 130 is used to store another analgesic drug (such as fentanyl). Before delivery, medical staff connect the analgesic drug delivery device 100 to the mother and ensure that the first and second drug containers 120 are filled with appropriate analgesic drugs. Before the device is started, necessary system self-checks are performed to ensure that the drug delivery system is working properly. The drive module 110 calculates the optimal injection ratio of the two drugs according to a set algorithm to ensure maximum analgesic effect and reduce the risk of side effects.

[0085] Through the patient request unit 210, the mother can actively request analgesia. After receiving the request signal, the drive module 110 begins to deliver the medication. For example, the first medication cartridge 120 starts the delivery of bupivacaine according to the set dosage and injection rate, with an initial dose of 0.25% to 0.5% bupivacaine, injected at a rate of 10 to 15 mL; the second medication cartridge 130 simultaneously starts the delivery of fentanyl to enhance the analgesic effect, with a specific dosage of 1 to 2 μg / kg, adjusted according to the mother's specific response.

[0086] In this embodiment, based on the detected regular waveform curve and the characteristics of the peak period of uterine contractions, the information processing unit 500 calculates the preset ratio of drug delivery. For example, the ratio of bupivacaine to fentanyl is set to 1:1, and the second drug container 130 and the first drug container 120 are driven to inject drugs simultaneously through the drive module 110.

[0087] During each peak of uterine contractions, the EEG signal detection module 300 collects the mother's brainwave signals in real time and transmits the data to the information processing unit 500. These signals reflect the mother's brain activity, especially in terms of pain perception and emotional changes. The information processing unit 500 preprocesses the received EEG signals, including filtering and noise reduction, to remove interference signals and ensure data accuracy. The information processing unit 500 analyzes the characteristics of the EEG signals to assess the mother's pain status. Specific analyses by the information processing unit 500 to assess the mother's pain status include: calculating the frequency of the EEG to determine if there is an increase in specific frequency bands related to pain (such as an increase in beta or gamma waves); assessing the energy distribution of different frequency bands to determine if there are high-frequency components related to pain; and calculating the average amplitude, variance, and slope of the EEG to assess the changing trends of brain activity. Preferably, the information processing unit 500 can also extract time-domain and frequency-domain features from the EEG signals to assess the mother's stress level. The information processing unit 500 specifically extracts the following features: 1. Time-domain features: Calculates the average voltage level of the EEG signal, reflecting the overall intensity of brain activity; assesses the volatility of the EEG signal, with a larger variance indicating a higher level of brain activity; measures the rise or fall rate of the EEG signal, with a larger slope indicating a rapid brain response to stimuli; records the time point when the EEG signal reaches its maximum value, helping to identify peak periods of brain activity. 2. Frequency-domain features: Converts the EEG signal into the frequency domain, analyzing the energy distribution of different frequency components. Common EEG frequency bands include delta waves (0.5–4 Hz), theta waves (4–8 Hz), alpha waves (8–12 Hz), beta waves (12–30 Hz), and gamma waves (30–100 Hz). In particular, an increase in beta and gamma waves is often associated with high stress levels; calculate the energy density of each frequency band to assess the relative contribution of different frequency components. A higher power spectral density indicates stronger energy in that frequency band, suggesting a connection to the mother's anxiety or pain perception; calculate the absolute power of each frequency band or its proportion relative to the total power to help quantify the importance of different frequency bands; measure the width of the spectrum to assess the complexity of the EEG signal. A wider spectral bandwidth indicates that the brain is in a more complex state of activity.

[0088] Furthermore, the information processing unit 500 constructs a comprehensive Stress Index (SI) based on the extracted time-domain and frequency-domain features. This index is used to quantify the current stress level of the postpartum woman. The specific calculation method for the Stress Index SI is as follows:

[0089] SI = w1 × Average Amplitude + w2 × Variance + w3 × β Wave Power + w4 × γ Wave Power

[0090] Wherein, w1, w2, w3, and w4 are weighting coefficients. In this embodiment, these weighting coefficients are obtained based on clinical experience and literature review, or based on statistical analysis of experimental data. These weighting coefficients are preferably optimized based on clinical experience and experimental data.

[0091] The information processing unit 500 compares the SI (Self-Induced Stress) with a preset threshold to determine the mother's stress level. When the SI exceeds the threshold, it indicates that the mother is in a state of high stress; conversely, when the SI is below the threshold, it indicates that the mother's stress level is relatively stable. Based on the analysis results of the electroencephalogram (EEG) signals, the information processing unit 500 dynamically adjusts the drug injection dosage. If the EEG signals indicate that the mother is in a state of high stress, the information processing unit 500 controls the analgesic drug delivery device 100 to increase the drug dosage; if the EEG signals indicate that the mother's stress level is relatively stable, the information processing unit 500 controls the analgesic drug delivery device 100 to maintain the current dosage or appropriately reduce the dosage.

[0092] According to a preferred embodiment, the information processing unit 500 dynamically adjusts the drug injection dosage based on the mother's stress state index (SI).

[0093] Specifically, the information processing unit 500 is configured to: when SI is below a threshold, control the analgesic drug delivery device 100 to maintain the current drug dosage to avoid overdose. At this time, the system appropriately reduces the amount of drug injected to prevent side effects caused by drug accumulation.

[0094] Specifically, the information processing unit 500 is configured to control the analgesic drug delivery device 100 to increase the drug dosage when the threshold ≤ SI < the high threshold, in order to alleviate the pain and discomfort of the mother. In this embodiment, the specific increase is adjusted linearly or non-linearly based on the specific value of SI.

[0095] Specifically, the information processing unit 500 is configured to: when SI ≥ a high threshold, control the analgesic drug delivery device 100 to significantly increase the drug dosage to quickly relieve the mother's high stress level. At this time, the system will prioritize the use of more potent analgesics (such as sufentanil) and combine them with other adjunctive drugs (such as ropivacaine) if necessary.

[0096] In this embodiment, when the mother experiences increased pain, she can send a request signal through the patient request unit 210 on the hand gripper 200. The patient request unit 210 includes a vibration sensor 211, which can detect the mother's tapping behavior. After receiving the request signal, the information processing unit 500, in conjunction with the current uterine contraction rhythm and EEG signals, reassesses the mother's pain status and generates a new medication injection instruction. If the mother's pain requires additional analgesic medication, the patient request unit 210 will appropriately increase the medication dosage according to a preset safety range. To avoid overdose, the patient request unit 210 sets a minimum interval (e.g., 5 minutes) after each manual request to prevent frequent requests from leading to medication overdose.

[0097] The information processing unit 500, in conjunction with the uterine contraction rhythm data collected by the uterine contraction detection module 400, further optimizes the adjustment of the drug injection dosage. The specific coordinated adjustment method of the information processing unit 500 is as follows: During the peak of each contraction, the drug injection dosage is increased based on the mother's stress state index (SI) and contraction intensity to ensure the mother receives sufficient analgesia when most needed; during the intervals between contractions, the drug injection dosage is reduced, or even suspended, to avoid side effects caused by drug accumulation; as the frequency of contractions increases, the baseline level of the drug injection dosage is gradually increased to adapt to the mother's gradually increasing pain demands. For example, when the contraction frequency increases from once every 10 minutes to once every 5 minutes, the system will correspondingly increase the dosage increase.

[0098] In this embodiment, as the frequency of uterine contractions increases, the information processing unit 500 gradually adjusts the drug injection volume according to the changes in the contraction rhythm. The specific adjustment method of the information processing unit 500 is as follows: During the initial peak contraction period: 5 μg of sufentanil is injected as the first dose; during subsequent peak contractions: at each peak contraction period, a mixture of 0.3 μg / mL sufentanil and 0.1% ropivacaine is injected, with the injection volume gradually increasing by a preset increment (e.g., 0.5 mL each time) as the frequency of contractions increases; maximum injection volume limit: to ensure safety, the information processing unit 500 sets the total injection volume within every 20-30 minutes to not exceed 5 mL. During the intercontraction interval, the information processing unit 500 reduces the drug injection volume to avoid side effects caused by drug accumulation. For example, during the intercontraction interval, the information processing unit 500 may pause drug injection or maintain only a low background infusion.

[0099] The emotional information acquisition unit 230 on the hand grip strengthener 200 includes a voice recognizer 231 and a player 232, used to collect the mother's voice and provide emotional support. When the mother exhibits anxiety or fear, the system will play soothing music or voice prompts through the player 232 to help her relax and reduce psychological stress. If the mother's voice decibel exceeds a preset threshold (e.g., 80dB) and lasts for an extended period, the system will issue an alarm to remind medical staff to pay attention to the mother's emotional state and provide additional support as needed.

[0100] The system monitors the mother's vital signs (such as heart rate, blood pressure, and blood oxygen saturation) in real time and combines this data with that from the uterine contraction detection module 400 and the electroencephalogram (EEG) signal detection module 300 to comprehensively assess the mother's health status. If the system detects any abnormalities (such as abnormal fetal heart rate, excessively high or low maternal blood pressure, etc.), it will immediately stop medication administration and issue an alarm to notify medical staff. Medical staff can then take timely and necessary intervention measures based on the system's prompts to ensure the safety of both mother and baby.

[0101] The information processing unit 500 records and stores data such as the time of each contraction, medication dosage, EEG signals, and emotional information. Based on historical data, the system automatically learns and optimizes the analgesia regimen, ensuring more precise and effective pain relief each time. Medical staff can view the system-generated reports at any time to understand the mother's analgesia effect and physiological response, enabling more informed treatment decisions. For example, if the mother experiences pain again and sends a new request signal during medication delivery, the information processing unit 500 will reassess the mother's stress level and contraction signals, and adjust the medication dosage accordingly.

[0102] This embodiment also provides an analgesic method. In this embodiment, an example is taken where a CPU is integrated into an analgesic drug delivery device 100, such as... Figure 4 As shown, except for the different control method of the information processing unit 500 on the analgesic drug delivery device 100, the other hardware is the same as in the previous embodiment.

[0103] Another aspect of this application relates to a physiological parameter detection module 600. The physiological parameter detection module 600 includes a blood oxygen detection unit, a blood pressure detection unit, and / or a heart rate detection unit. The physiological parameter detection module 600 also includes a power supply unit for supplying power to the aforementioned detection units.

[0104] The physiological parameter detection module 600 can be configured as a smart bracelet worn on the wrist of the postpartum woman. The physiological parameter detection module 600 can replace the loop 252 at one end of the spring-loaded wrist strap 250 in the hand grip strengthener 200.

[0105] The hand grip strengthener 200 is equipped with an emotion information acquisition unit 230, which includes a voice recognition device 231 and a player 232. The emotion information acquisition unit 230 can collect the mother's voice. When the mother's physiological parameters (e.g., blood pressure, blood oxygen, heart rate) are outside the normal range for postpartum women, the information processing unit 500 controls the analgesic drug delivery device 100 to stop delivering analgesic drugs to the mother and issues a voice prompt through the emotion information acquisition unit 230. After medical personnel confirm that the mother's physiological parameters are unaffected, based on secondary confirmation by the medical personnel through their handheld device or other means (i.e., a signal sent to the information processing unit 500 via their handheld device or other means for secondary confirmation), the information processing unit 500 controls the analgesic drug delivery device 100 to resume operation and continues the aforementioned drug administration method after restoring historical data. Historical data includes all data generated by the mother during this delivery period before the analgesic drug delivery device 100 is stopped delivering analgesic drugs to the mother. For example, during the interval between the second regular contractions, if the mother's blood oxygen level falls below a preset threshold, the information processing unit 500 controls the analgesic drug delivery device 100 to stop delivering analgesic drugs to the mother. Simultaneously, based on the voice recognition unit 231 of the emotion information acquisition unit 230 detecting speech exceeding a preset decibel level for a preset time, the information processing unit 500 sends a sound notification to the medical staff via the player 232, containing the mother's blood oxygen level and the message indicating that the speech exceeded the preset decibel level for a preset time. After the medical staff sends a secondary confirmation signal via the button 251 on the analgesic drug delivery device 100, the information processing unit 500 acquires the signal collected by the contraction detection module 400, which has not yet stopped collecting data, and controls the analgesic drug delivery device 100 to provide analgesic drugs to the mother according to her current contraction status.

[0106] It should be noted that the specific embodiments described above are exemplary. Those skilled in the art can devise various solutions inspired by the disclosure of this invention, and these solutions all fall within the scope of this invention and its protection. Those skilled in the art should understand that this specification and its accompanying drawings are illustrative and do not constitute a limitation on the claims. The scope of protection of this invention is defined by the claims and their equivalents. This specification contains multiple inventive concepts; terms such as "preferredly," "according to a preferred embodiment," or "specifically" indicate that the corresponding paragraph discloses an independent concept. The applicant reserves the right to file divisional applications based on each inventive concept. Throughout the text, features introduced by "preferredly" are merely optional and should not be construed as mandatory. Therefore, the applicant reserves the right to abandon or delete relevant preferred features at any time.

Claims

1. A pain relief delivery system for use during labor, comprising: An analgesic drug delivery device (100) for administering medication to a woman during uterine contractions, characterized in that... The system also includes: EEG signal detection module (300) for acquiring EEG signals that characterize brain activity. A contraction detection module (400) for acquiring signals of uterine pulsation during contractions, and An information processing unit (500) is connected to the analgesic drug delivery device (100), the electroencephalogram signal detection module (300), and the uterine contraction detection module (400) respectively. The information processing unit (500) is configured to control the analgesic drug delivery device (100) to adjust the type and dosage of the drug to reduce the pain of the mother during labor pains based on the uterine contraction status reflected by the signals collected by the uterine contraction detection module (400) and the maternal stress status reflected by the signals collected by the electroencephalogram (EEG) signal detection module (300). The system also includes a gripper (200) with a patient request unit (210) configured with a tapping signal transmission mode. When a patient taps the grip strengthener (200), causing the patient request unit (210) of the grip strengthener (200) to generate a request signal that is sent to the information processing unit (500), the information processing unit (500) analyzes the calibration index α of the electroencephalogram (EEG) signals collected by the EEG signal detection module (300). The information processing unit (500) forms a regular waveform curve based on the original bioelectric potential signal related to uterine muscle contraction collected by the uterine contraction detection module (400). When the regular waveform curve has characteristics that conform to the peak period of uterine contraction, analgesic drugs are injected into the parturient at a preset injection volume range. The preset injection volume range is modified based on the generation time node of the regular waveform curve that conforms to the peak period of uterine contraction, which increases or decreases the preset injection volume.

2. The analgesic drug delivery system according to claim 1, characterized in that, The contraction detection module (400) is used to collect data that conforms to the characteristics of the peak contraction period. The information processing unit (500) is driven by the generation time node of the regular waveform curve that conforms to the characteristics of the peak contraction period to control the type and amount of analgesic drug delivery device (100) during the process of the mother experiencing labor pain.

3. The analgesic drug delivery system according to claim 1 or 2, characterized in that, The information processing unit (500) is configured to increase the injection volume of the analgesic drug delivery device (100) by a preset increment each time a regular waveform curve conforming to the characteristics of the peak period of uterine contractions is generated.

4. The analgesic drug delivery system according to claim 1 or 2, characterized in that, The analgesic drug delivery device (100) includes a first drug container (120) and a second drug container (130) driven by a driven module (110) that holds different types of drugs respectively.

5. The analgesic drug delivery system according to claim 1, characterized in that, The uterine contraction detection module (400) includes a potential signal acquisition unit (410), wherein the potential signal acquisition unit (410) acquires the original bioelectric potential signal of the parturient woman in the abdomen of the parturient woman in order to obtain the parturient woman's uterine contraction state.

6. The analgesic drug delivery system according to claim 3, characterized in that, The information processing unit (500) is configured to generate an initial drug injection dose that matches the brain information presented by the EEG signal detection module (300), and to dynamically adjust the initial drug injection dose according to the original bioelectric potential signal presented by the uterine contraction detection module (400).

7. The analgesic drug delivery system according to claim 6, characterized in that, Sending a request signal is achieved through a patient request unit (210) containing a vibration sensor (211) within the gripper (200).

8. The analgesic drug delivery system according to claim 7, characterized in that, The grip strengthener (200) also has an elastic shell (240) and a pressure component (220) for adjusting the expansion degree of the elastic shell (240). The pressure component (220) is signal-connected to the information processing unit (500). As the degree of uterine contractions of the parturient increases, the information processing unit (500) controls the elastic deformation of the pressure component (220) to make the grip strengthener (200) match the parturient's grip strength.

9. The analgesic drug delivery system according to claim 8, characterized in that, The pressure assembly (220) includes at least two elastic support rods (221) and a pressure sensor (223) located at the intersection of the elastic support rods (221) and capable of sensing the pressure value of the corresponding elastic support rod (221). When the pressure value transmitted by the pressure sensor (223) exceeds a preset threshold, a spring compressor (222) located at one end of the elastic support rod (221) for adjusting the spring compression range of the elastic support rod (221) is decompressed under the control of the information processing unit (500) to adjust the expansion degree of the elastic shell of the gripper (200).

10. The analgesic drug delivery system according to claim 7, characterized in that, The patient request unit (210) is a component of a tapping signal transmission mode.

11. The analgesic drug delivery system according to claim 8, characterized in that, The surface of the elastic shell (240) is provided with at least one finger sleeve (260), wherein the area corresponding to the at least one finger sleeve (260) is provided with a vibration sensor (211) capable of sensing the tapping behavior generated in the area corresponding to it.

12. The analgesic drug delivery system according to claim 8, characterized in that, The surface of the elastic shell (240) is provided with a spring-loaded wrist strap (250) so that the suspended grip strengthener (200) can spring back to the mother's hand and regain control of the analgesic drug delivery device (100).

13. The analgesic drug delivery system according to claim 12, characterized in that, One end of the elastic wrist strap (250) is provided with an adjustment unit including a spring and a locking component, and the other end is provided with a loop (252) that fits around the mother's wrist.

14. The analgesic drug delivery system according to claim 1, characterized in that, The information processing unit (500) is configured to record the dosage of analgesic drugs used by the analgesic drug delivery device (100) and send it to the hospital information system to verify whether the dosage of the recovered analgesic drugs is correct.

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