An orthopedic prosthesis material and a method for producing the same

Abstract

The application belongs to the technical field of plastic materials, and particularly relates to a prosthesis material for orthopedics and a preparation method thereof. The preparation method comprises the following steps: (1) pretreating carbon fibers to obtain pretreated carbon fibers; (2) modifying the carbon fibers by using KH792 to obtain silane-modified carbon fibers; (3) mixing the silane-modified carbon fibers and N,N dimethylformamide, continuously adding polyethylene glycol diacetate and a condensing agent, heating and reacting, and removing the N,N dimethylformamide by rotary evaporation to obtain modified carbon fibers; and (4) uniformly mixing PEEK powder, the modified carbon fibers and carboxylated carbon nanotubes, and performing mold pressing to obtain the prosthesis material for orthopedics. The prosthesis material for orthopedics prepared by the application is safe to use, has high mechanical properties and good fatigue resistance.

Description

Technical Field

[0001] This invention belongs to the field of plastic surgery materials technology, specifically relating to a prosthetic material for plastic surgery and its preparation method. Background Technology

[0002] In the field of plastic surgery, facial contour reshaping and repair is a crucial clinical need, with applications spanning congenital malformations, post-traumatic bone defects, post-tumor resection reconstruction, and cosmetic contour adjustments. To achieve ideal morphological improvement and functional restoration, the selection of implant materials is paramount. Ideal plastic surgery implants should possess good biocompatibility, excellent mechanical properties, long-term stability, and processability, while also integrating well with host tissue to avoid complications such as rejection, infection, and displacement.

[0003] Currently, commonly used plastic surgery implant materials include silicone, expanded polytetrafluoroethylene (ePTFE), autologous bone, allogeneic bone, and biodegradable polymer materials. Among them, silicone is widely used in rhinoplasty, chin augmentation, and other surgeries due to its ease of shaping and low cost, but it has problems such as a large difference in elastic modulus between silicone and bone, easy displacement, and capsular contracture. Although expanded polytetrafluoroethylene (ePTFE) has good tissue compatibility, it has weak resistance to infection and lacks sufficient structural support, making it unsuitable for weight-bearing areas. Although autologous bone grafting has the best biocompatibility and osseointegration ability, its clinical application is limited by factors such as donor site damage, high absorption rate, and difficulty in shaping.

[0004] In recent years, with the development of high-performance polymer materials, polyetheretherketone (PEEK) has gradually attracted attention in the field of plastic surgery due to its excellent comprehensive properties. PEEK is a semi-crystalline thermoplastic polymer with excellent biocompatibility. Furthermore, PEEK materials can be highly personalized and precisely customized through computer-aided design and manufacturing (CAD / CAM) or 3D printing technology, making it particularly suitable for the reconstruction of complex anatomical structures. In the fields of plastic surgery and craniofacial repair, the demand for high-performance implant materials is increasing, especially in applications such as facial bony reconstruction, contour shaping, and complex defect repair, requiring implants to possess excellent mechanical properties, good biocompatibility, and long-term stability. To further improve the mechanical properties of PEEK materials, especially its stiffness and load-bearing capacity, carbon fiber reinforced PEEK composites (CFR-PEEK) have emerged. By introducing carbon fibers into the PEEK matrix, the tensile strength, flexural strength, and shear strength of the material can be significantly improved, enhancing its structural stability and resistance to deformation, thereby expanding its application potential in high-stress environments. Chinese patent CN113501982B discloses a carbon fiber reinforced PEEK composite material, its preparation method and application. The prepared composite material has the characteristics of being acid-free, having good interfacial compatibility, good mechanical properties and good biocompatibility.

[0005] However, existing carbon fiber reinforced PEEK composites still suffer from significant performance bottlenecks: although shear strength has been improved to some extent, their flexural fatigue life is still insufficient to meet the practical needs of long-term clinical use. Especially under dynamic facial loading environments (such as chewing and facial expressions), the material is repeatedly subjected to cyclic stress, easily leading to the formation and propagation of microcracks at the fiber-matrix interface, resulting in interlaminar delamination or fracture, ultimately causing prosthesis failure. This problem exposes the current imbalance between rigidity and toughness in materials: excessive rigidity, while increasing initial strength, sacrifices the material's fatigue resistance and energy dissipation capacity. Summary of the Invention

[0006] The purpose of this invention is to provide a prosthesis material for plastic surgery and a method for preparing the same.

[0007] To achieve the above objectives, the present invention provides the following technical solution:

[0008] A method for preparing implant materials for plastic surgery includes the following steps:

[0009] (1) The carbon fiber is pretreated to obtain pretreated carbon fiber;

[0010] (2) The carbon fiber was modified with KH792 to obtain silane-modified carbon fiber;

[0011] (3) Silane carbon fibers and N,N Dimethylformamide mixture was added, followed by the addition of polyethylene glycol diacetate and a condensing agent. The mixture was heated to react, and N,N was removed by rotary evaporation. Dimethylformamide was used to obtain modified carbon fibers;

[0012] (4) PEEK powder, modified carbon fiber and carboxylated carbon nanotubes are mixed evenly and molded to obtain a prosthesis material for orthopedic surgery.

[0013] Preferably, the number average molecular weight of polyethylene glycol diacetate is 1000-2000.

[0014] The weak interfacial adhesion between PEEK powder and carbon fiber leads to poor wettability, resulting in defects and ultimately severely impacting mechanical properties, particularly flexural fatigue life, which is highly sensitive to the interface. Existing technologies using acyl chloride carbon fiber primarily provide chemical anchoring points, offering good improvement in shear strength but not ideal improvement in flexural fatigue life. This invention improves the flexural fatigue life of the material by modifying the carbon fiber. Specifically, this invention utilizes the reaction of polyethylene glycol diacetate (PEG) with a primary amino group at one end of KH792 to form a strong, flexible long chain anchored at one end to the carbon fiber. This PEG chain can freely entangle with the PEEK matrix, constructing a long-chain flexible polymer interfacial layer with one end covalently bonded to the carbon fiber and the other end firmly entangled with PEEK, thereby improving the flexural fatigue life of the material.

[0015] Preferably, the pretreatment method is to sinter the carbon fiber and then oxidize it to obtain pretreated carbon fiber.

[0016] Preferably, the molar ratio of polyethylene diacetate to KH792 is (1-1.2):1.

[0017] Preferably, the molding conditions are: a heating rate of 10... Increase temperature by 15°C / min to 160°C Insulate at 180°C for 40 minutes After 50 minutes, continue heating at a rate of 10. Increase the temperature by 15°C / min to 400°C 410°C, pressure 5 Molding at 10MPa for 20 days 30 minutes, at a cooling rate of 10 Cool to room temperature at 15°C / min.

[0018] Preferably, the mass ratio of PEEK powder, modified carbon fiber and carboxylated carbon nanotubes is 100:(20-25):(6-10).

[0019] Preferably, the carboxylated carbon nanotubes include carboxylated carbon nanotube A, carboxylated carbon nanotube B, and carboxylated carbon nanotube C.

[0020] Preferably, the carboxylated carbon nanotubes A have a diameter of 10-20 nm, a length of 10-30 μm, and a bulk density of 0.25-0.28 g / cm³. 3 The carboxyl content is 2.00-2.03 wt%; the diameter of carboxylated carbon nanotubes B is 20-30 nm, the length is 10-30 μm, and the bulk density is 0.20-0.22 g / cm³. 3 The carboxyl content is 1.20-1.23 wt%; the diameter of carboxylated carbon nanotubes (C) is 30-50 nm, the length is 10-20 μm, and the bulk density is 0.22-0.24 g / cm³. 3 The carboxyl content is 0.70-0.73 wt%.

[0021] Preferably, the carboxylated carbon nanotubes comprise carboxylated carbon nanotube A, carboxylated carbon nanotube B, and carboxylated carbon nanotube C in a mass ratio of (0.8-1.0):(1.3-1.5):(0.3-0.5).

[0022] This invention improves the shear strength of orthopedic prosthesis materials by adding carboxylated carbon nanotubes with specific parameters to the material. Analysis shows that the compounded carbon nanotubes form CNTs with appropriate diameter, length, and packing density, and contain a suitable amount of carboxyl groups. This results in better dispersion in the system, making it easier to penetrate and embed into the carbon fiber / PEEK matrix. Simultaneously, the carboxyl groups can interact and bond with the hydroxyl groups at the PEEK chain ends during high-temperature molding, effectively resisting interlayer slippage.

[0023] This invention provides a prosthesis material for use in orthopedic surgery prepared by the aforementioned method.

[0024] Compared with the prior art, the advantages and beneficial effects of the present invention are as follows:

[0025] 1. This invention provides a prosthetic material for orthopedic surgery with high biocompatibility. By functionalizing the surface of carbon fiber, the interfacial bonding force between carbon fiber and PEEK matrix is ​​enhanced, effectively inhibiting crack propagation and significantly improving the durability of the material under cyclic loading, thereby greatly improving the flexural fatigue life of the prosthesis.

[0026] 2. This invention introduces composite carbon nanotubes with specific aspect ratios and carboxyl group densities, which are uniformly dispersed in a PEEK matrix to form a multi-scale reinforcing network. This network effectively transfers stress and hinders dislocation movement, significantly improving the shear strength and overall mechanical stability of the prosthesis material.

[0027] 3. This invention balances the rigidity and toughness of the material by synergistically optimizing the carbon fiber interface modification and carbon nanotube multi-scale reinforcement, maintaining high modulus and high strength while improving energy dissipation capacity, thus solving the technical problems of traditional reinforced composite materials being brittle and having poor fatigue resistance. Detailed Implementation

[0028] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0029] All raw materials used in the following embodiments of the present invention are commercially available products:

[0030] Carbon fiber, Resoo Trading (Shanghai) Co., Ltd., 6MM carbon fiber short chopped C6-4.0 / 240-T190.

[0031] PEEK powder, CAS number 31694-16-3, brand: Victrex, model 706. Distributor: Dongguan Kadar Plastic Raw Materials Co., Ltd.

[0032] Condensing agent: EDC, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide.

[0033] KH792, CAS No. 1760-24-3.

[0034] Example 1

[0035] This embodiment provides a method for preparing implant materials for orthopedic surgery, including the following steps:

[0036] (1) Sinter the carbon fiber at 350°C for 100 min to decompose the original sizing agent on its surface, and then put it into an oxidation reaction furnace. At 270°C, preheated air is continuously introduced and maintained for 50 min to obtain pretreated carbon fiber.

[0037] (2) Mix 0.03g KH792 by mass ratio and 15mL of 90% ethanol aqueous solution by volume, adjust the pH to 5.0 with 0.1mol / L acetic acid, hydrolyze at 40℃ for 50min, add 1g of pretreated carbon fiber, stir and react at 40℃ for 4h, wash with water until neutral, and dry at 80℃ for 12h to obtain silane modified carbon fiber.

[0038] (3) Mix silane carbon fibers and N,N at a mass ratio of 1:10 Dimethylformamide was mixed, and polyethylene glycol diacetate and a condensing agent were added. The molar ratio of polyethylene glycol diacetate to KH792 was 1:1, and the molar ratio of the condensing agent to the carboxyl groups of polyethylene glycol diacetate was 1:1. The mixture was stirred at 60°C for 100 min, and N,N was removed by rotary evaporation. Dimethylformamide was used to obtain modified carbon fibers; polyethylene glycol diacetate, with a number average molecular weight of 1000, was produced by Shenzhen Meiluo Technology Co., Ltd.

[0039] (4) PEEK powder, modified carbon fiber and carboxylated carbon nanotubes with a mass ratio of 100:21:7 were mixed and stirred at 300 rpm for 60 min. The temperature was raised to 160°C at a rate of 15°C / min and held for 50 min. The temperature was then raised to 400°C at a rate of 10°C / min and molded at a pressure of 10 MPa for 30 min. The temperature was then lowered to room temperature at a rate of 15°C / min to obtain a prosthesis material for plastic surgery.

[0040] The carboxylated carbon nanotubes include carboxylated carbon nanotube A, carboxylated carbon nanotube B, and carboxylated carbon nanotube C in a mass ratio of 1:1.4:0.4. Carboxylated carbon nanotube A has a diameter of 10-20 nm, a length of 10-30 μm, and a packing density of 0.27 g / cm³. 3 Carboxyl group content 2.00wt%. Model CNT304. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes B have a diameter of 20-30nm, a length of 10-30μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 1.23wt%. Model CNT305. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes (C) have a diameter of 30-50nm, a length of 10-20μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 0.73wt%. Model: CNT306. Beijing Deco Island Gold Technology Co., Ltd.

[0041] Example 2

[0042] This embodiment provides a method for preparing implant materials for orthopedic surgery, including the following steps:

[0043] (1) Sinter the carbon fiber at 350°C for 100 min to decompose the original sizing agent on its surface, put it into an oxidation reaction furnace, and then continuously pass preheated air at 270°C for 50 min to obtain pretreated carbon fiber.

[0044] (2) Mix 0.03g KH792 by mass ratio and 15mL of 90% ethanol aqueous solution by volume, adjust the pH to 5.0 with 0.1mol / L acetic acid, hydrolyze at 40℃ for 50min, add 1g of pretreated carbon fiber, stir and react at 40℃ for 4h, wash with water until neutral, and dry at 80℃ for 12h to obtain silane modified carbon fiber.

[0045] (3) Mix silane carbon fibers and N,N at a mass ratio of 1:10 Dimethylformamide was mixed, and polyethylene glycol diacetate and a condensing agent were added. The molar ratio of polyethylene glycol diacetate to KH792 was 1.1:1, and the molar ratio of the condensing agent to the carboxyl groups of polyethylene glycol diacetate was 1:1. The mixture was stirred at 70°C for 120 min, and N,N was removed by rotary evaporation. Dimethylformamide was used to obtain modified carbon fibers; polyethylene glycol diacetate, with a number average molecular weight of 1000, was produced by Shenzhen Meiluo Technology Co., Ltd.

[0046] (4) PEEK powder, modified carbon fiber and carboxylated carbon nanotubes with a mass ratio of 100:20:9 were mixed and stirred at 300 rpm for 60 min. The temperature was raised to 160°C at a rate of 15°C / min and held for 50 min. The temperature was then raised to 400°C at a rate of 10°C / min and molded at a pressure of 10 MPa for 30 min. The temperature was then lowered to room temperature at a rate of 15°C / min to obtain a prosthesis material for plastic surgery.

[0047] The carboxylated carbon nanotubes include carboxylated carbon nanotube A, carboxylated carbon nanotube B, and carboxylated carbon nanotube C in a mass ratio of 0.8:1.5:0.3. Carboxylated carbon nanotube A has a diameter of 10-20 nm, a length of 10-30 μm, and a packing density of 0.27 g / cm³. 3 Carboxyl group content 2.00wt%. Model CNT304. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes B have a diameter of 20-30nm, a length of 10-30μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 1.23wt%. Model CNT305. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes (C) have a diameter of 30-50nm, a length of 10-20μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 0.73wt%. Model: CNT306. Beijing Deco Island Gold Technology Co., Ltd.

[0048] Comparative Example 1

[0049] The difference between this comparative example and Example 1 is that the number-average molecular weight of polyethylene glycol diacetate is 400. Shenzhen Meiluo Technology Co., Ltd.

[0050] Comparative Example 2

[0051] The difference between this comparative example and Example 1 is that the number-average molecular weight of polyethylene glycol diacetate is 3400. Shenzhen Meiluo Technology Co., Ltd.

[0052] Comparative Example 3

[0053] The difference between this comparative example and Example 1 is that this method for preparing a prosthetic material for orthopedic surgery includes the following steps:

[0054] (1) Sinter the carbon fiber at 350°C for 100 min to decompose the original sizing agent on its surface, put it into an oxidation reaction furnace, and then continuously pass preheated air at 270°C for 50 min to obtain pretreated carbon fiber.

[0055] (2) Mix 0.03g KH792 by mass ratio and 15mL of 90% ethanol aqueous solution by volume, adjust the pH to 5.0 with 0.1mol / L acetic acid, hydrolyze at 40℃ for 50min, add 1g of pretreated carbon fiber, stir and react at 40℃ for 4h, wash with water until neutral, and dry at 80℃ for 12h to obtain modified carbon fiber.

[0056] (3) PEEK powder, modified carbon fiber and carboxylated carbon nanotubes with a mass ratio of 100:21:7 were mixed and stirred at 300 rpm for 60 min. The temperature was raised to 160°C at a rate of 15°C / min and held for 50 min. The temperature was then raised to 400°C at a rate of 10°C / min and molded at a pressure of 10 MPa for 30 min. The temperature was then lowered to room temperature at a rate of 15°C / min to obtain a prosthesis material for plastic surgery.

[0057] The carboxylated carbon nanotubes include carboxylated carbon nanotube A, carboxylated carbon nanotube B, and carboxylated carbon nanotube C in a mass ratio of 1:1.4:0.4. Carboxylated carbon nanotube A has a diameter of 10-20 nm, a length of 10-30 μm, and a packing density of 0.27 g / cm³. 3 Carboxyl group content 2.00wt%. Model CNT304. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes B have a diameter of 20-30nm, a length of 10-30μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 1.23wt%. Model CNT305. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes (C) have a diameter of 30-50nm, a length of 10-20μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 0.73wt%. Model: CNT306. Beijing Deco Island Gold Technology Co., Ltd.

[0058] Comparative Example 4

[0059] The difference between this comparative example and Example 1 is that the carboxylated carbon nanotubes include carboxylated carbon nanotubes A and B in a mass ratio of 1:1.4. Carboxylated carbon nanotube A has a diameter of 10-20 nm, a length of 10-30 μm, and a bulk density of 0.27 g / cm³. 3 Carboxyl group content 2.00wt%. Model CNT304. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes B have a diameter of 20-30nm, a length of 10-30μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 1.23wt%. Model: CNT305. Beijing Deco Island Gold Technology Co., Ltd.

[0060] Comparative Example 5

[0061] The difference between this comparative example and Example 1 is that the carboxylated carbon nanotubes include carboxylated carbon nanotubes A, B, and C in a mass ratio of 0.6:1.7:0.7. Carboxylated carbon nanotube A has a diameter of 10-20 nm, a length of 10-30 μm, and a packing density of 0.27 g / cm³. 3 Carboxyl group content 2.00wt%. Model CNT304. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes B have a diameter of 20-30nm, a length of 10-30μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 1.23wt%. Model CNT305. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes (C) have a diameter of 30-50nm, a length of 10-20μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 0.73wt%. Model: CNT306. Beijing Deco Island Gold Technology Co., Ltd.

[0062] Comparative Example 6

[0063] The difference between this comparative example and Example 1 is that the carboxylated carbon nanotubes include carboxylated carbon nanotubes A, B, and C in a mass ratio of 1.2:1:0.2. Carboxylated carbon nanotube A has a diameter of 10-20 nm, a length of 10-30 μm, and a packing density of 0.27 g / cm³. 3 Carboxyl group content 2.00wt%. Model CNT304. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes B have a diameter of 20-30nm, a length of 10-30μm, and a bulk density of 0.22g / cm³. 3 Carboxyl content 1.23wt%. Model CNT305. Beijing Deco Island Gold Technology Co., Ltd. The carboxylated carbon nanotubes (C) have a diameter of 30-50nm, a length of 10-20μm, and a bulk density of 0.22g / cm³. 3Carboxyl content 0.73wt%. Model: CNT306. Beijing Deco Island Gold Technology Co., Ltd.

[0064] Comparative Example 7

[0065] This comparative example is the product of Example 1 of Chinese Patent CN113501982B, which discloses a carbon fiber reinforced PEEK composite material, its preparation method, and its application.

[0066] Performance testing

[0067] The materials prepared in Examples 1-2 and Comparative Examples 1-7 were subjected to performance tests.

[0068] 1. Shear strength: Refer to GB / T3355 The test was conducted in 2005. The sample loading speed was 2 mm / min. Six samples were tested in each group, and the average value was taken.

[0069] 2. Bending strength: Refer to GB / T1449 The test was conducted in 2005, with a sample loading speed of 2 mm / min. Six samples were tested in each group, and the average value was taken.

[0070] 3. Bending fatigue performance test: Refer to GB / T35465.1 The test was conducted in 2017 with an alternating cycle frequency of 25Hz and a load limited to 60% of the maximum stress, and the fatigue resistance was measured for the number of cycles.

[0071] 4. In vitro cell compatibility evaluation: Referring to the requirements for cytotoxicity experiments in GB / T16886 "Biological Evaluation of Medical Devices", L929 mouse fibroblasts were selected as the test cell line. The test extract was prepared using the extraction method, and 6 extract samples were prepared for each group. Under the conditions of 37℃ and 5% CO2, the extract was applied to L929 cells for 24 hours. The cell viability was detected by the CCK8 method. The viability of each sample was ≥80% and was considered qualified.

[0072] The results are shown in Table 1.

[0073] Table 1 Test Results

[0074]

[0075] As shown in Table 1, the prosthetic materials used in plastic surgery in Examples 1-2 have good safety, high mechanical properties, and good fatigue resistance, which are significantly better than existing products.

[0076] Comparative Examples 1 and 2 show that the molecular weight of polyethylene glycol diacetate has a significant impact on fatigue resistance and shear strength. Too low a molecular weight results in too short a chain, forming a thin and hard interfacial layer, leading to poor fatigue resistance. Conversely, too high a molecular weight results in a soft and thick weak boundary layer at the interface, which is prone to slippage under stress, causing a decrease in shear strength. Furthermore, an excessively thick flexible layer also becomes a weak point for stress concentration, further reducing fatigue resistance.

[0077] As can be seen from Comparative Examples 4-6, the ratio and composition of carbon nanotubes have a significant impact on the shear properties and flexural strength of materials used in orthopedic prostheses. Only carbon nanotubes with specific ratios and parameters can achieve performance improvements.

[0078] The above description represents the preferred embodiments of the present invention. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A method for preparing implant materials for plastic surgery, characterized in that, Includes the following steps: (1) The carbon fiber is pretreated to obtain pretreated carbon fiber; (2) The carbon fiber was modified with KH792 to obtain silane-modified carbon fiber; (3) Silane carbon fibers and N,N Dimethylformamide mixture was added, followed by the addition of polyethylene glycol diacetate and a condensing agent. The mixture was heated to react, and N,N was removed by rotary evaporation. Dimethylformamide was used to obtain modified carbon fibers; the number average molecular weight of polyethylene glycol diacetate was 1000-2000. (4) PEEK powder, modified carbon fiber and carboxylated carbon nanotubes are mixed evenly and molded to obtain a prosthesis material for plastic surgery. Carboxylated carbon nanotubes include carboxylated carbon nanotube A, carboxylated carbon nanotube B, and carboxylated carbon nanotube C in a mass ratio of (0.8-1.0):(1.3-1.5):(0.3-0.5); Carboxylated carbon nanotubes A have a diameter of 10-20 nm, a length of 10-30 μm, and a bulk density of 0.25-0.28 g / cm³. 3 The carboxyl content is 2.00-2.03 wt%; the diameter of carboxylated carbon nanotubes B is 20-30 nm, the length is 10-30 μm, and the bulk density is 0.20-0.22 g / cm³. 3 The carboxyl content is 1.20-1.23 wt%; the diameter of carboxylated carbon nanotubes (C) is 30-50 nm, the length is 10-20 μm, and the bulk density is 0.22-0.24 g / cm³. 3 The carboxyl content is 0.70-0.73 wt%.

2. The method for preparing implant materials for plastic surgery according to claim 1, characterized in that, The pretreatment method is as follows: carbon fiber is sintered and then oxidized to obtain pretreated carbon fiber.

3. The method for preparing implant materials for plastic surgery according to claim 1, characterized in that, The molar ratio of polyethylene glycol diacetate to KH792 is (1-1.2):

1.

4. The method for preparing implant materials for plastic surgery according to claim 1, characterized in that, The molding conditions are: a heating rate of 10... Increase temperature by 15°C / min to 160°C Insulate at 180°C for 40 minutes After 50 minutes, continue heating at a rate of 10. Increase the temperature by 15°C / min to 400°C 410°C, pressure 5 Molding at 10MPa for 20 days 30 minutes, at a cooling rate of 10 Cool to room temperature at 15°C / min.

5. The method for preparing implant materials for plastic surgery according to claim 1, characterized in that, The mass ratio of PEEK powder, modified carbon fiber and carboxylated carbon nanotubes is 100:(20-25):(6-10).

6. A prosthetic material for use in orthopedic surgery prepared by the method according to any one of claims 1-5.

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