Bending-adjustable guide wire

Abstract

The invention discloses a bending-adjustable guide wire which comprises a sleeve assembly, a bending-adjustable guide wire body and a bending-adjustable guide wire body, the sleeve assembly defines a containing channel and comprises a bending-adjustable pipe, and the bending-adjustable pipe at least defines a far-end section of the containing channel; the core wire is arranged in the containing channel in a penetrating mode, the far end of the core wire is connected with the far end of the bend adjusting pipe or the position close to the far end, and the near end of the core wire extends out of the containing channel from the near end of the containing channel; wherein the sleeve assembly is provided with a first limiting structure, the core wire is provided with a second limiting structure, and the first limiting structure and the second limiting structure can move mutually in the axial direction and limit mutual movement in the circumferential direction. The bending-adjustable guide wire can smoothly intervene into a target blood vessel, the rotation of the core wire relative to the bending-adjustable tube is limited through the cooperation of the first limiting structure and the sliding part, and the probability that the far end of the core wire is broken is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to an adjustable bending guide wire. BACKGROUND

[0002] At present, the percutaneous intervention treatment of intracranial neurovascular diseases adopts the following method: after the successful percutaneous puncture of the blood vessel and the placement of a sheath, a micro guide wire, a micro catheter, a guide catheter, a distal access catheter and other access instruments are put in. Through the combined use and cooperation of various access instruments, the micro guide wire or catheter is put into the target position in the blood vessel, thereby establishing the access of the treatment instrument into the target position in the blood vessel. Among various access instruments, the micro guide wire, as the smallest leading instrument, plays the most basic role of guiding and tracking.

[0003] Due to the multiple tortuousness and many bifurcations of neurovasculars, it is difficult for a single straight guide wire to enter the bifurcated branch vessels. An effective method is to shape the head end of the guide wire into a certain shape, so that the guide wire can better enter the branch vessels or aneurysms. At present, the shape of the head end of the guide wire is shaped manually by a shaping needle before the guide wire enters the blood vessel or is shaped before leaving the factory. The doctor can only rely on the shape of the guide wire shaped in advance to perform certain fine operations to select the target blood vessel. However, the blood vessel path of the actual patient is different, and the doctor cannot completely and accurately know the condition of the blood vessel and the shape of the head end of the guide wire before using the guide wire. Therefore, the shape of the guide wire shaped outside the body often cannot match the specific path of the blood vessel, resulting in difficulty in selection and even failure of the intervention. SUMMARY

[0004] The technical problem to be solved by the present application is that the head end shape of the existing adjustable bending guide wire does not match the shape of the blood vessel and cannot enter the blood vessel with large tortuosity angle and many branches. In view of the defects of the prior art, the present application provides an adjustable bending guide wire.

[0005] The technical problem of the present application is solved by the following technical scheme:

[0006] According to an embodiment of the present application, an adjustable bending guide wire is provided, which comprises a sleeve assembly defining a receiving channel, the sleeve assembly comprising a bending adjusting tube defining at least a distal end section of the receiving channel; a core wire arranged in the receiving channel, a distal end of the core wire being connected to a distal end or a position close to the distal end of the bending adjusting tube, and a proximal end of the core wire extending out of the receiving channel from a proximal end of the receiving channel; wherein the sleeve assembly is provided with a first limiting structure, the core wire is provided with a second limiting structure, and the first limiting structure and the second limiting structure can axially move relative to each other and limit the relative movement in the circumferential direction.

[0007] In some embodiments of the present application, the sleeve assembly further comprises a support tube in communication with the bend-adjusting tube and defining a proximal section of the accommodation channel; the first limiting structure comprises a first limiting portion provided on the support tube, and the second limiting structure comprises a first sliding member, the first limiting portion being in axial sliding cooperation with the first sliding member and being restricted from rotating circumferentially relative to the first sliding member.

[0008] In some embodiments of the present application, the first limiting portion is configured as a first sliding groove formed on a tube wall of the support tube, the first sliding groove forming a first opening at a proximal end of the support tube; at least a portion of the first sliding member is configured to extend axially along the core wire, and the first sliding member is slidably inserted into the first sliding groove.

[0009] In some embodiments of the present application, the first sliding member comprises a sliding portion and a first stop portion connected to a proximal end of the sliding portion, the distal end of the sliding portion being inserted into the first sliding groove, the proximal end of the sliding portion extending out of the first sliding groove from the first opening, the circumferential dimension of the first stop portion being greater than the circumferential dimension of the first opening, and the distal end of the first stop portion being capable of abutting against the proximal end of the support tube.

[0010] In some embodiments of the present application, the first sliding member is configured as a tubular member, the first sliding member being sleeved outside the core wire, a tube wall of the first sliding member being provided with a second sliding groove, the second sliding groove forming a second opening at a distal end of the first sliding member; the first limiting portion is configured to extend axially along the support tube, the distal end of the first limiting portion being connected to the proximal end of the support tube, and the proximal end of the first limiting portion being slidably inserted into the second sliding groove through the second opening.

[0011] In some embodiments of the present application, the distal end of the second sliding groove is provided with a tapered portion, and the proximal end of the first limiting portion is provided with a second stop portion, the distal end of the second stop portion being capable of abutting against the proximal end of the tapered portion.

[0012] In some embodiments of the present application, the sleeve assembly further comprises a transition tube defining an intermediate section of the accommodation channel, a distal end of the transition tube being in communication with the bend-adjusting tube, and a proximal end of the transition tube being in communication with the support tube; a connecting sleeve having a proximal end connected to the support tube and a distal end connected to the transition tube, the core wire being movably arranged in the connecting sleeve.

[0013] In some embodiments of the present application, the first limiting structure comprises a second limiting portion arranged on the connecting sleeve, and the second limiting structure comprises a second sliding member, the second limiting portion and the second sliding member are axially slidingly matched and limit the circumferential mutual rotation; wherein the second limiting portion is configured as a third sliding groove arranged on the pipe wall of the connecting sleeve, and the second sliding member is configured to extend along the axial direction of the core wire, and the second sliding member is slidingly arranged in the third sliding groove.

[0014] In some embodiments of the present application, the core wire comprises a distal end portion connected with the bending tube, the distal end portion comprises a first segment and a second segment connected with the proximal end of the first segment, the diameter of the distal end portion gradually decreases from the proximal end to the distal end, and the second segment comprises a plurality of transition segments connected in sequence, and the taper of any two adjacent transition segments is not equal from the proximal end to the distal end.

[0015] In some embodiments of the present application, the second segment has a distal end portion connected with the first segment, and the distal end portion of the second segment and the first segment are arranged inside the bending tube.

[0016] In some embodiments of the present application, the bending tube comprises a bending segment, a plurality of cutouts are arranged on the pipe wall of the bending segment, the plurality of cutouts are arranged in sequence along the axial direction and form openings towards the same side, wherein the cutouts comprise a first cutout segment and a second cutout segment arranged in the circumferential direction, the first cutout segment and the second cutout segment both extend along the axial direction, and the cutouts further comprise a third cutout segment, both ends of the third cutout segment are connected with the proximal end side of the first cutout segment and the proximal end side of the second cutout segment respectively.

[0017] In some embodiments of the present application, the minimum circumferential length between the first cutout segment and the second cutout segment is less than half of the circumference of the bending tube, and the circumferential length of the third cutout segment is greater than half of the circumference of the bending tube.

[0018] According to the adjustable bending guide wire provided by the present application, the bending tube is arranged, the proximal end of the core wire is pulled to move relative to the sleeve assembly towards the proximal end side, the distal end of the core wire is used to apply a proximal end pulling force to the distal end of the bending tube, the bending tube is deformed and bent, and the bending deformation degree of the bending tube is controlled by fine adjustment of the movement distance of the core wire, so that the bending shape of the bending tube is actively adjusted according to the branch shape and tortuosity angle of the target blood vessel, and the adjustable bending guide wire can be smoothly intervened into the target blood vessel. Moreover, the first limiting structure and the second limiting structure are matched to limit the circumferential rotation of the core wire relative to the bending tube, the large shear stress generated by the torsion of the distal end of the core wire is reduced, and the probability of fracture of the core wire is reduced, thereby improving the reliability of the adjustable bending guide wire. BRIEF DESCRIPTION OF DRAWINGS

[0019] The application will be further described below in conjunction with the accompanying drawings and embodiments. In the drawings:

[0020] Figure 1 A cross-sectional structural schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0021] Figure 2 A cross-sectional structural schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0022] Figure 3 A cross-sectional structural schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0023] Figure 4 A cross-sectional structural schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0024] Figure 5 A cross-sectional structural schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0025] Figure 6 A cross-sectional structural schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0026] Figure 7 A cross-sectional structural schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0027] Figure 8 A structural schematic diagram of the bending tube of one embodiment of the application is shown;

[0028] Figure 9 A structural schematic diagram of the bending tube of one embodiment of the application is shown;

[0029] Figure 10 A partial structural schematic diagram of the bending tube of one embodiment of the application is shown;

[0030] Figure 11 A structural schematic diagram of the bending section of the bending tube of one embodiment of the application in a bending state is shown;

[0031] Figure 12 A structural schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0032] Figure 13 A parts explosion schematic diagram of the adjustable bending guide wire of one embodiment of the application is shown;

[0033] Figure 14 A structural schematic diagram of the connecting sleeve of one embodiment of the application is shown;

[0034] Figure 15 Structure diagram showing the first and second limiting structures between the support tube and the guide wire of one embodiment of the present application;

[0035] Figure 16 Structure diagram showing the first and second limiting structures between the support tube and the guide wire of one embodiment of the present application;

[0036] Figure 17 Structure diagram showing the first and second limiting structures between the support tube and the guide wire of one embodiment of the present application;

[0037] Figure 18 Structure diagram showing the first and second limiting structures between the support tube and the guide wire of one embodiment of the present application;

[0038] Figure 19 Structure diagram showing the first and second limiting structures between the support tube and the guide wire of one embodiment of the present application; Figure 18 Structure diagram showing the cross-section of the A-A part of the present application;

[0039] Figure 20 Structure diagram showing the core wire of one embodiment of the present application;

[0040] Figure 21 Structure diagram showing the core wire of one embodiment of the present application;

[0041] Figure 22 Structure diagram showing the cross-section of the distal end of the bending tube of one embodiment of the present application;

[0042] Figure 23 Structure diagram showing the cross-section of the B-B part of the present application; Figure 22

[0043] Structure diagram showing the cross-section of the C-C part of the present application; Figure 24 Figure 22 Structure diagram showing the cross-section of the C-C part of the present application;

[0044] Figure 25 Structure diagram showing the cross-section of the C-C part of the present application; Figure 22 Structure diagram showing the cross-section of the C-C part of the present application. Specific embodiments

[0045] In order to have a clearer understanding of the technical features, objectives and effects of the present application, the specific embodiments of the present application will be described in detail with reference to the drawings.

[0046] ​Exemplary embodiments of the present disclosure will be described below in greater detail with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it is understood that the present disclosure can be embodied in various forms without being limited to the embodiments set forth herein. Rather, these embodiments are provided so that the present disclosure will be thorough and complete, and will fully convey the scope of the present disclosure to those skilled in the art.

[0047] It is to be understood that the terms used herein are merely for the purpose of describing particular embodiments and are by no means intended to be limiting. As used herein, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. The terms "comprises," "comprising," "includes," "including," and the like are inclusive and therefore specify the presence of stated features, steps, operations, elements, and / or components, but do not preclude the presence or addition of one or more other features, steps, operations, elements, components, and / or groups thereof. The method steps, processes, and operations described herein are not to be construed as necessarily requiring their performance in the particular order in which they are described, unless specifically identified as an order dependent step. It is also to be understood that additional or alternative steps can be employed.

[0048] Although the terms first, second, third, and the like can be used herein to describe various elements, components, regions, layers and / or sections, these elements, components, regions, layers and / or sections should not be limited by these terms. These terms can be only used to distinguish one element, component, region, layer or section from another region, layer or section. Unless the context clearly indicates otherwise, terms such as "first," "second," and the like are used herein to describe a variety of elements, components, regions, layers and / or sections, and do not imply an order or sequence unless clearly indicated by the context. Thus, a first element, component, region, layer or section discussed below could be termed a second element, component, region, layer or section without departing from the teachings of the example embodiments.

[0049] Spatially relative terms, such as "inner," "outer," "beneath," "below," "lower," "above," "upper," and the like, can be used herein for ease of description to describe one element or feature's relationship to another element(s) or feature(s) as illustrated in the figures. Spatially relative terms can be intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" or "over" the other elements or features. Thus, the example term "below" can encompass both an orientation of above and below. The device can be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

[0050] In this application, unless otherwise explicitly specified and limited, the terms "mounting", "connecting", "connecting", "fixing" and the like should be understood in a broad sense, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be mechanically connected, or it can be electrically connected or communicate with each other; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the internal communication of two elements or the interaction relationship between two elements, unless otherwise explicitly limited. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0051] It should be noted that "distal" and "proximal" are used as directional words, which are common terms in the field of interventional medical devices, wherein "distal" means the end far from the operator during the operation, and "proximal" means the end close to the operator during the operation. Axial refers to the direction parallel to the center line of the distal end and the proximal end of the medical device; radial refers to the direction perpendicular to the above axial direction.

[0052] In the embodiments of the present application, the comparison of the bending performance of two samples can be obtained by three-point bending test. Specifically, the first sample is placed on two support points with a certain distance, the distance between the two support points is less than the length of the two samples, a downward load is applied to the midpoint of the two support points, and the sample is pressed to a certain distance, and the load of the sample at this time is tested. The same method is used to test the second sample, and the distance between the two support points and the distance of the sample are the same as when testing the first sample. The smaller the load, the easier to bend, the better the flexibility, and the higher the bending performance. For example, the first sample can be a support tube 11, and the second sample can be a bending tube 12.

[0053] As Figure 1As shown, an embodiment of the present application provides an adjustable bending guide wire 100, the adjustable bending guide wire 100 comprises a sleeve assembly 10 and a core wire 20, the sleeve assembly 10 comprises a support tube 11 and a bending tube 12, the sleeve assembly 10 defines a containing channel 101, the support tube 11 is located at a proximal end and defines a proximal end section of the containing channel 101, the bending tube 12 is located at a distal end and defines a distal end section of the containing channel 101, the proximal end section and the distal end section of the containing channel 101 are communicated, the bending performance of the bending tube 12 is higher than that of the support tube 11, the core wire 20 is arranged in the containing channel 101, a distal end of the core wire 20 is connected with the distal end of the bending tube 12, a proximal end of the core wire 20 is arranged outside the containing channel 101 from the proximal end of the containing channel 101, that is, the proximal end of the core wire 20 is arranged outside the support tube 11 from the proximal end of the support tube 11, and the proximal end of the core wire 20 can move in an axial direction relative to the support tube 11, by pulling the proximal end of the core wire 20 to move relative to the support tube 11 in a direction towards the proximal end, a pulling force towards the proximal end is applied to the distal end of the bending tube 12 by the distal end of the core wire 20, the bending tube 12 is deformed in bending, and the deformation degree of the bending tube 12 in bending is controlled by fine adjustment of the moving distance of the core wire 20, so that the bending shape of the bending tube 12 is actively adjusted according to the branch shape and tortuosity angle of the target blood vessel, and the adjustable bending guide wire 100 can be smoothly intervened into the target blood vessel.

[0054] Further, the sleeve assembly 10 is provided with a first limiting structure 30, and the core wire 20 is provided with a second limiting structure 40 matched with the first limiting structure 30, in the matching process of the first limiting structure 30 and the second limiting structure 40, the first limiting structure 30 and the second limiting structure 40 can move in an axial direction relative to each other, but the first limiting structure 30 and the second limiting structure 40 are limited to move in a circumferential direction relative to each other, in the process of intervention into the target blood vessel or bending, the core wire 20 is prevented from rotating relative to the bending tube 12, the cutting stress generated by the torsion of the distal end of the core wire 20 is reduced, and the probability of fracture of the core wire 20 is reduced, and the reliability of the adjustable bending guide wire is improved.

[0055] In some embodiments, the second limiting structure 40 can be connected with the core wire 20 by welding, gluing or the like. In other embodiments, the second limiting structure 40 and the core wire 20 are an integrated structure formed integrally, for example, the second limiting structure 40 is a structure feature with a specific shape processed from part of the core wire 20, so that it can be matched with the first limiting structure 30, without welding operation, the process is simple, and based on the integrated structure, the risk of falling off of the second limiting structure 40 from the core wire 20 is avoided, and the reliability is higher.

[0056] In the present embodiment, the distal end of the core wire 20 can be directly connected to the distal end or a position close to the distal end of the shape-adjustable tube 12 by welding, gluing or the like. In other embodiments, the distal end of the core wire 20 can be indirectly connected to the distal end or a position close to the distal end of the shape-adjustable tube 12, for example, by connecting the distal end of the core wire 20 to the distal end or a position close to the distal end of the shape-adjustable tube 12 through the cap portion 24 (see Figure 3 ) of the shape-adjustable tube 12.

[0057] The shape-adjustable tube 12 has a higher bending performance than the support tube 11, i.e., the shape-adjustable tube 12 has better flexibility relative to the support tube 11, and is more likely to bend when subjected to the pulling force of the core wire 20, so as to conform to the shape of the curved blood vessel and achieve the adjustable bending of the head end of the adjustable bending guide wire 100. The support tube 11 has higher hardness, rigidity and bending resistance relative to the shape-adjustable tube 12, and can effectively transmit the pushing force to the distal end of the adjustable bending guide wire 100, such as the shape-adjustable tube 12, during the intervention of the target blood vessel of the adjustable bending guide wire 100.

[0058] In some embodiments, the support tube 11 and the shape-adjustable tube 12 are made of the same material, but the thickness of the wall of the shape-adjustable tube 12 is smaller than that of the support tube 11, so that the shape-adjustable tube 12 has a higher bending performance than the support tube 11, i.e., the shape-adjustable tube 12 has better flexibility relative to the support tube 11. The materials of the support tube 11 and the shape-adjustable tube 12 include, but are not limited to, stainless steel, cobalt-chromium alloy and nickel-titanium alloy.

[0059] To further improve the flexibility of the shape-adjustable tube 12, the tube wall of the shape-adjustable tube 12 is provided with a plurality of hollow portions 102 (see Figure 8 ), for example, the hollow portions 102 are long holes extending along the circumferential direction of the shape-adjustable tube 12, and the plurality of hollow portions 102 are arranged in sequence and staggered along the axial direction of the shape-adjustable tube 12, so that the shape-adjustable tube 12 forms a hollow lumen structure.

[0060] In some embodiments, the support tube 11 and the shape-adjustable tube 12 are made of different materials, and the hardness and rigidity of the material of the support tube 11 are higher than those of the shape-adjustable tube 12, so that the shape-adjustable tube 12 has a higher bending performance than the support tube 11.

[0061] It can be understood that the support tube 11 and the shape-adjustable tube 12 can be directly connected, and the distal end of the support tube 11 is connected to the proximal end of the shape-adjustable tube 12, for example, the support tube 11 and the shape-adjustable tube 12 are connected as a whole by laser welding, soldering or adhesive bonding. Alternatively, the support tube 11 and the shape-adjustable tube 12 can be indirectly connected through other components, as long as the support tube 11 and the shape-adjustable tube 12 are connected in communication.

[0062] In some embodiments, as shown in Figure 3 and Figure 12As shown, the sleeve assembly 10 further comprises a transition tube 13, the support tube 11 and the adjustable bending tube 12 are indirectly connected through the transition tube 13. Specifically, the transition tube 13 is arranged between the support tube 11 and the adjustable bending tube 12, the proximal end of the transition tube 13 is connected with the distal end of the support tube 11, and the distal end of the transition tube 13 is connected with the proximal end of the adjustable bending tube 12, the support tube 11, the transition tube 13 and the adjustable bending tube 12 together define a receiving channel 101, and the core wire 20 is arranged in the receiving channel 101.

[0063] In the embodiment, the bending performance of the transition tube 13 is higher than that of the support tube 11, and / or the bending performance of the adjustable bending tube 12 is higher than that of the transition tube 13. Specifically, the support tube 11 has better hardness, rigidity and bending resistance than the transition tube 13 and the adjustable bending tube 12, so that the support tube 11 can provide sufficient pushing force to the transition tube 13 and the adjustable bending tube 12 during pushing the adjustable bending guide wire 100 to the target blood vessel. The transition tube 13 has better flexibility than the support tube 11, so as to conform to the bending shape of the blood vessel, and at the same time, the transition tube 13 has better hardness and rigidity than the adjustable bending tube 12, so that the transition tube 13 has supporting property, which is beneficial to transmitting the pushing force to the adjustable bending tube 12 at the head end of the adjustable bending guide wire 100. In other embodiments, the bending performance of the adjustable bending tube 12 can also be the same as that of the transition tube 13.

[0064] In detail, similar to the adjustable bending tube 12, the transition tube 13 can be provided with a plurality of hollow portions 102, for example, the hollow portions 102 are long holes extending along the circumferential direction of the transition tube 13, and the plurality of hollow portions 102 are arranged in sequence and staggered along the axial direction of the transition tube 13, so that the transition tube 13 forms a hollow lumen structure, and the transition tube 13 has better flexibility than the support tube 11.

[0065] In some embodiments, as shown in Figure 8 and Figure 9 As shown, the adjustable bending tube 12 has a first side and a second side located on both sides of the axis thereof respectively, and the first side of the adjustable bending tube 12 is provided with at least one cutout 1221 on the tube wall thereof, the cutout 1221 is arranged on the first side relative to the axis of the adjustable bending tube 12, so that the tube wall material of the first side of the adjustable bending tube 12 is less than that of the second side, and thus, when subjected to the pulling force of the core wire 20, the adjustable bending tube 12 bends in the direction from the second side to the first side, so that the first side is located on the inside of the adjustable bending tube 12, and the second side is located on the outside of the adjustable bending tube 12, so as to ensure that the head end of the adjustable bending guide wire 100 can bend and deform in a specific direction when the core wire 20 is pulled, thereby improving the certainty of the bending direction of the head end of the adjustable bending guide wire 100 and optimizing the operability of the adjustable bending guide wire 100 in the process of interventional target blood vessel.

[0066] The technical solutions of the present application will be further described in detail below in combination with specific embodiments.

[0067] Example 1

[0068] like Figure 2 As shown, in this embodiment, the adjustable guide wire 100 includes a support tube 11, an adjusting tube 12, a core wire 20, a first connecting tube 14, a second developing element 17, and a first sliding element 41.

[0069] The support pipe 11 can be a steel pipe, providing good support. The support pipe 11 includes a main body segment 111 and a connecting segment 112 connected to the distal end of the main body segment 111. The diameter of the connecting segment 112 is smaller than the diameter of the main body segment 111, making the distal end of the support pipe 11 stepped. The bending pipe 12 is connected to the distal end of the connecting segment 112. The wall thickness of the bending pipe 12 is the same as the wall thickness of the connecting segment 112, and the outer diameter of the bending pipe 12 is the same as the outer diameter of the connecting segment 112.

[0070] The proximal end of the first connecting pipe 14 is sleeved outside the support pipe 11, and the distal end of the first connecting pipe 14 is sleeved outside the bending pipe 12. The support pipe 11, the first connecting pipe 14, and the bending pipe 12 are welded into an integral structure through a welding process. It should be noted that when the adjustable guide wire 100 undergoes bending deformation, due to the difference in bending performance between the support pipe 11 and the bending pipe 12, stress concentration is easily generated at the connection between the support pipe 11 and the bending pipe 12, causing rapid bending deformation at the connection between the support pipe 11 and the bending pipe 12, which can easily lead to breakage at the connection between the support pipe 11 and the bending pipe 12. Therefore, by setting the first connecting pipe 14 between the support pipe 11 and the bending pipe 12, the strength of the connection structure between the support pipe 11 and the bending pipe 12 is improved. Furthermore, the length of the first connecting tube 14 extends along the axial direction. The first connecting tube 14 can lengthen the easily deformable weak area, thereby distributing the deformation evenly and avoiding excessive deformation at a certain point (i.e., the connection point between the distal end of the support tube 11 and the proximal end of the bending tube 12), thus reducing the probability of the adjustable guide wire 100 bending and breaking. In other embodiments, the proximal end of the first connecting tube 14 may also be located inside the support tube 11, and the distal end of the first connecting tube 14 may be located inside the bending tube 12.

[0071] In this embodiment, to further improve the flexibility of the bending pipe 12, the pipe wall of the bending pipe 12 is provided with multiple hollowed-out portions 102 (see...). Figure 8 For example, the hollow part 102 is an elongated hole extending along the circumferential direction of the bending tube 12. Multiple hollow parts 102 are arranged alternately along the axial direction of the bending tube 12, so that the bending tube 12 forms a hollow tube cavity structure.

[0072] In this embodiment, Figure 2In the embodiment, the core wire 20 comprises a proximal segment 21 and a distal segment 23 connected to each other, the proximal segment 21 is located at the proximal side relative to the distal segment 23, the distal end of the distal segment 23 is connected to the distal end of the bending tube 12, the distal segment 23 is arranged inside the bending tube 12, the proximal segment 21 is arranged in the support tube 11, and the proximal end of the proximal segment 21 extends out of the support tube 11 to the outside of the support tube 11, wherein, from the proximal end to the distal end, the diameter of the distal segment 23 gradually decreases, and the maximum diameter of the distal segment 23 is smaller than the maximum diameter of the proximal segment 21, so as to effectively improve the support of the proximal segment 21 and the flexibility of the distal segment 23 of the adjustable bending guide wire 100, and in the process of moving the core wire 20, the support is provided by the proximal segment 21, and the flexibility of the distal segment 23 makes the distal end of the adjustable bending guide wire 100 more easily bent.

[0073] Further, referring to Figure 3 , the distal end of the core wire 20 is provided with a cap portion 24, the cap portion 24 is in a semispherical shape, the cap portion 24 has a curved surface portion 241 and a flat surface portion 242, the cap portion 24 is located at the side of the distal end of the bending tube 12 and is connected to the bending tube 12. Specifically, the curved surface portion 241 is arranged towards the distal end, the flat surface portion 242 abuts against the distal end of the bending tube 12, and the distal end of the distal segment 23, the distal end of the bending tube 12 and the flat surface portion 242 are connected by glue or soldering.

[0074] Wherein, in the axial direction, the cap portion 24 covers at least part of the distal end surface of the bending tube 12, and in the process of advancing the adjustable bending guide wire 100 in the blood vessel, the cap portion 24 directly contacts the blood vessel wall as the head end of the adjustable bending guide wire 100, the smooth curved surface of the curved surface portion 241 provides a guiding effect, and reduces the friction between the head end of the adjustable bending guide wire 100 and the blood vessel wall, so that the adjustable bending guide wire 100 moves more smoothly in the blood vessel.

[0075] It should be noted that the shape of the curved surface portion 241 includes but is not limited to spherical surface, conical surface, umbrella-shaped curved surface.

[0076] Further, the second developing member 17 is arranged outside the bending tube 12, which facilitates the development and visibility of the adjustable bending guide wire 100 in the body, so that the operator can clearly observe the bending direction and bending angle of the bending tube 12 of the adjustable bending guide wire 100, and provide visual guidance for superselecting to the target blood vessel, and improve the success probability of the operation.

[0077] The second developing member 17 includes but is not limited to a shape such as a wire, a tube, a rod, etc. In the embodiment, the second developing member 17 is in a spring shape, the second developing member 17 is sleeved outside the bending tube 12, the proximal end of the second developing member 17 abuts against the distal end of the first connecting tube 14, and the distal end of the second developing member 17 abuts against the cap portion 24.

[0078] In other embodiments, the second developing member 17 can not be additionally provided, and the bending tube 12 itself has developing property, for example, the bending tube 12 can be a metal material having developing property.

[0079] In the embodiment, as shown in Figure 2 The first limiting structure 30 includes a first limiting part 31 arranged on the support tube, and the second limiting structure 40 includes a first sliding member 41 arranged on the outer circumferential surface of the core wire 20 close to the proximal end. The first sliding member 41 can slide on the first limiting part 31 in the axial direction of the core wire, and the first limiting part 31 and the first sliding member 41 are limited to rotate in the circumferential direction. That is, the first limiting part 31 limits the first sliding member 41 to rotate relative to the sleeve assembly in the circumferential direction of the core wire. During the intervention of the target blood vessel or the bending process, the adjustable bending guide wire prevents the core wire 20 from rotating relative to the bending tube 12, reduces the large shear stress generated by the torsion of the distal end of the core wire 20, and further reduces the probability of core wire fracture, thereby improving the reliability of the adjustable bending guide wire.

[0080] Embodiment Two

[0081] In the embodiment, as shown in Figure 3 and Figure 12 The adjustable bending guide wire 100 includes a support tube 11, a transition tube 13, a bending tube 12, a core wire 20, a second connecting tube 18, a second developing member 17, and a first sliding member 41.

[0082] The support tube 11 is a steel tube, and has good supportability. In the axial direction, the transition tube 13 is arranged between the support tube 11 and the bending tube 12. The proximal end of the transition tube 13 is connected to the distal end of the support tube 11, and the distal end of the transition tube 13 is connected to the proximal end of the bending tube 12. The support tube 11, the transition tube 13, and the bending tube 12 jointly define a containing channel 101. The core wire 20 is arranged in the containing channel 101. The distal end of the core wire 20 is connected to the distal end of the bending tube 12, and the proximal end of the core wire 20 extends out of the containing channel 101 from the proximal end of the support tube 11.

[0083] Specifically, the support tube 11 comprises a body segment 111 and a connecting segment 112 connected to the distal end of the body segment 111, the diameter of the connecting segment 112 is smaller than that of the body segment 111, so that the distal end of the support tube 11 is arranged in a stepped manner. The transition tube 13 is sleeved outside the connecting segment 112, the proximal end of the transition tube 13 abuts against the distal end of the body segment 111, and the transition tube 13 and the support tube 11 are connected and fixed by welding or bonding. The wall thickness of the body segment 111 of the support tube 11 is greater than that of the transition tube 13, so as to improve the support of the proximal end of the adjustable bending guide wire 100. The wall thickness of the transition tube 13 is smaller than that of the body segment 111, so that the transition tube 13 has higher bending performance relative to the support tube 11. The outer diameter of the transition tube 13 is the same as that of the connecting segment 112, so that the outer peripheral surface of the adjustable bending guide wire 100 is smooth as a whole without protrusions, which is beneficial to the smoother movement of the adjustable bending guide wire 100 in the blood vessel.

[0084] The proximal end of the bending tube 12 is sleeved in the transition tube 13, and the transition tube 13 and the bending tube 12 are connected and fixed by welding or bonding. The diameter of the transition tube 13 is greater than that of the bending tube 12, so that the transition tube 13 has better hardness, rigidity and bending resistance relative to the bending tube 12, and the support of the adjustable bending guide wire 100 near the distal end side is improved. Understandably, the diameter of the bending tube 12 is smaller than that of the transition tube 13 and the support tube 11, so that the bending performance of the bending tube 12 is higher than that of the transition tube 13 and the support tube 11, and the bending tube 12 has better flexibility, so as to ensure that the bending tube 12 is easier to bend when the core wire 20 is pulled.

[0085] Further, in the direction from the proximal end to the distal end, the core wire 20 comprises a proximal end segment 21, an intermediate segment 22 and a distal end segment 23 connected in sequence, the distal end segment 23 is arranged in the bending tube 12, the intermediate segment 22 is arranged in the transition tube 13, the proximal end segment 21 is arranged in the support tube 11, and the proximal end of the proximal end segment 21 extends out of the accommodation channel 101 from the proximal end of the support tube 11.

[0086] In some embodiments, the proximal segment 21 and the distal segment 23 are both in the shape of an equal-diameter round rod, and the intermediate segment 22 is in the shape of a round rod and at least part of the intermediate segment 22 is in the shape of a variable-diameter round rod. In detail, the intermediate segment 22 is located between the proximal segment 21 and the distal segment 23, the proximal end of the intermediate segment 22 is connected to the distal end of the proximal segment 21, and the distal end of the intermediate segment 22 is connected to the proximal end of the distal segment 23, wherein the diameter of the distal segment 23 is smaller than the diameter of the proximal segment 21, the maximum diameter of the intermediate segment 22 is greater than the diameter of the proximal segment 21, the diameter of the proximal side of the intermediate segment 22 gradually increases from the proximal end to the distal end, so that the outer periphery of the connection between the intermediate segment 22 and the proximal segment 21 is smoothly transitioned, the diameter of the distal side of the intermediate segment 22 gradually decreases from the proximal end to the distal end, so that the outer periphery of the connection between the intermediate segment 22 and the distal segment 23 is smoothly transitioned, and when the core wire 20 is bent, the deformation of the connection between the intermediate segment 22 and the proximal segment 21 and the connection between the intermediate segment 22 and the distal segment 23 is uniformly distributed, so that the problem of stress concentration at the connection is avoided to cause excessive deformation, thereby reducing the probability of fracture of the core wire 20.

[0087] In some embodiments, the maximum diameter of the intermediate segment 22 is greater than the maximum diameter of the proximal segment 21, which can improve the support of the corresponding region of the intermediate segment 22 of the core wire 20 and the transition tube 13 of the adjustable bending guide wire 100, so as to provide greater pushing force to the head end of the adjustable bending guide wire 100 (i.e., the bending tube 12 and the distal segment 23). Based on the embodiment, the wall thickness of the body segment 111 of the support tube 11 is greater than the wall thickness of the transition tube 13, and the inner diameter of the transition tube 13 is the same as the outer diameter of the connection segment 112. Further, by setting the maximum diameter of the intermediate segment 22 to be greater than the maximum diameter of the proximal segment 21, the support of the intermediate segment 22 can be increased.

[0088] In some embodiments, the proximal segment 21, the intermediate segment 22, and the distal segment 23 are made of the same material and are integrally formed by one core wire 20, and the proximal segment 21 and the intermediate segment 22 are connected by laser welding, soldering, or adhesive.

[0089] In some embodiments, the proximal segment 21, the intermediate segment 22, and the distal segment 23 are made of the same material and are integrally formed by one core wire 20, and the proximal segment 21 and the intermediate segment 22 are connected by laser welding, soldering, or adhesive.

[0090] When the proximal segment 21 and the intermediate segment 22 are not integrally formed, to improve the stability of the connection between the proximal segment 21 and the intermediate segment 22, the adjustable bending guide wire 100 further comprises a second connecting tube 18 arranged in the accommodation channel 101 and sleeved on the core wire 20, and the second connecting tube 18 is connected to the proximal segment 21 and the intermediate segment 22 of the core wire 20 by laser welding, soldering or adhesive. In this embodiment, during the movement of the core wire 20 towards the proximal end, the second connecting tube 18 can also abut against the distal end of the connecting segment 112 to control the movement distance of the core wire 20, prevent the tip of the adjustable bending guide wire from being excessively bent, and damage the blood vessel.

[0091] In this embodiment, the wall of the transition tube 13 and the wall of the bending tube 12 are respectively provided with a plurality of hollow parts 102, for example, the hollow parts 102 are long holes extending in the circumferential direction of the bending tube 12, and the plurality of hollow parts 102 are arranged in the axial direction in sequence and staggered, so that the bending tube 12 and the transition tube 13 both form a hollow lumen structure, and the transition tube 13 and the bending tube 12 have better flexibility than the support tube 11.

[0092] Further, the distal end of the core wire 20 is provided with a cap part 24, the cap part 24 is in a semispherical shape, the cap part 24 has a curved surface part 241 and a flat surface part 242, the cap part 24 is located on one side of the distal end of the bending tube 12 and connected to the bending tube 12. Specifically, the curved surface part 241 is arranged towards the distal end, the flat surface part 242 abuts against the distal end of the bending tube 12, and the distal end of the proximal segment 23, the distal end of the bending tube 12 and the flat surface part 242 are connected by glue dispensing or soldering. In the axial direction, the cap part 24 covers at least part of the bending tube 12, and when the adjustable bending guide wire 100 is advanced in the blood vessel, the cap part 24 directly contacts the blood vessel wall as the tip of the adjustable bending guide wire 100, uses the smooth curved surface of the curved surface part 241 to provide a guiding effect, and reduces the friction between the tip of the adjustable bending guide wire 100 and the blood vessel wall, so that the adjustable bending guide wire 100 moves more smoothly in the blood vessel. It should be noted that the shape of the curved surface part 241 includes but is not limited to spherical surface, conical surface and umbrella-shaped curved surface.

[0093] Further, the second developing member 17 is arranged outside the bending tube 12, so that the adjustable bending guide wire 100 can be developed and visible in the body, so that the operator can clearly observe the bending direction and bending angle of the bending tube 12 of the adjustable bending guide wire 100, and provide visual guidance for superselecting to the target blood vessel, thereby improving the success probability of the operation. The second developing member 17 includes but is not limited to a shape such as a wire, a tube, and a rod. In the embodiment, the second developing member 17 is in a spring shape, the second developing member 17 is sleeved outside the bending tube 12, the proximal end of the second developing member 17 abuts against the distal end of the transition tube 13, and the distal end of the second developing member 17 abuts against the cap portion 24. The distal end segment 23 of the core wire 20, the cap portion 24, the bending tube 12, and the second developing member 17 are fixed together by bonding or welding.

[0094] In the embodiment, as shown in Figure 3 , the first limiting structure 30 includes a first limiting portion 31 arranged on the support tube 11, and the second limiting structure 40 includes a first sliding member 41 arranged on the outer circumferential surface of the core wire 20 close to the proximal end. The first sliding member 41 can slide on the first limiting portion 31 in the axial direction of the core wire, and the first limiting portion 31 and the first sliding member 41 are limited to rotate relative to each other in the circumferential direction, that is, the first limiting portion 31 limits the first sliding member 41 to rotate relative to the sleeve assembly in the circumferential direction of the core wire. During the intervention of the target blood vessel or the bending process, the core wire 20 is prevented from rotating relative to the bending tube 12, the large shear stress generated by the torsion at the distal end of the core wire 20 is reduced, and the probability of the core wire breaking is reduced, thereby improving the reliability of the adjustable bending guide wire.

[0095] Embodiment Three

[0096] The differences between the third embodiment and the second embodiment will be described below, and the same or similar parts between the third embodiment and the second embodiment will not be described here.

[0097] In the embodiment, as shown in Figure 4 , Figure 5 , and Figure 13 , the adjustable bending guide wire 100 includes the support tube 11, the transition tube 13, the bending tube 12, the core wire 20, the connecting sleeve 15, the second developing member 17, the first sliding member 41, and the second sliding member 42.

[0098] In the embodiment, the distal end of the support tube 11 is not provided with a stepped structure, the inner diameter of the support tube 11 is equal to the inner diameter of the transition tube 13, the outer diameter of the support tube 11 is equal to the outer diameter of the transition tube 13, and the distal end of the support tube 11 abuts against the proximal end of the transition tube 13.

[0099] In some embodiments, as shown in Figure 4As shown, since the steel pipes of the same diameter specification are difficult to be connected by welding, in order to connect and fix the support pipe 11 and the transition pipe 13 together by welding, the connecting sleeve pipe 15 is embedded in the inside of the support pipe 11 and the inside of the transition pipe 13, the proximal end of the connecting sleeve pipe 15 is arranged in the support pipe 11 and connected with the support pipe 11 by welding, and the distal end of the connecting sleeve pipe 15 is arranged in the transition pipe 13 and connected with the transition pipe 13 by welding, so as to connect and fix the support pipe 11 and the transition pipe 13 by welding by using the connecting sleeve pipe 15. In other embodiments, the proximal end of the connecting sleeve pipe 15 is sleeved outside the support pipe 11 and connected with the support pipe 11, and the distal end of the connecting sleeve pipe 15 is sleeved outside the transition pipe 13 and connected with the transition pipe 13.

[0100] In this embodiment, as shown in Figure 4 In the direction from the proximal end to the distal end, the core wire 20 includes the proximal end segment 21, the intermediate segment 22 and the distal end segment 23 connected in sequence, the distal end segment 23 is arranged in the bending adjustment pipe 12, the intermediate segment 22 is arranged in the transition pipe 13, and the proximal end segment 21 is arranged in the support pipe 11, and the proximal end of the proximal end segment 21 extends out of the accommodation channel 101 from the proximal end of the support pipe 11.

[0101] In this embodiment, the distal end segment 23 is in the shape of an equal-diameter round rod, at least part of the proximal end segment 21 and at least part of the intermediate segment 22 are in the shape of a variable-diameter round rod, and specifically, the intermediate segment 22 is located between the proximal end segment 21 and the distal end segment 23, the proximal end of the intermediate segment 22 is connected with the distal end of the proximal end segment 21, and the distal end of the intermediate segment 22 is connected with the proximal end of the distal end segment 23.

[0102] In some embodiments, the diameter of the distal end segment 23 is smaller than the minimum diameter of the proximal end segment 21 and the minimum diameter of the intermediate segment 22, so that the distal end segment 23 has the highest bending performance relative to the proximal end segment 21 and the intermediate segment 22, the maximum diameter of the proximal end segment 21 is greater than the maximum diameter of the intermediate segment 22, so that the proximal end segment 21 has the highest support performance relative to the intermediate segment 22 and the distal end segment 23, and the intermediate segment 22 has both support performance and flexibility, so that the intermediate segment 22 can provide sufficient pushing force to the distal end segment 23 while maintaining better flexibility to better adapt to the bending shape of the blood vessel.

[0103] It should be noted that the outer diameter of the proximal end segment 21 is reduced at the position corresponding to the connecting sleeve pipe 15, so as to avoid the connecting sleeve pipe 15 and enable the core wire 20 to move relative to the connecting sleeve pipe 15 in the axial direction, thereby realizing the bending adjustment function of the head end of the adjustable bending guide wire 100.

[0104] In this embodiment, as shown in Figure 5As shown, the first limiting structure 30 comprises a first limiting portion 31 arranged on the support tube 11 and a second limiting portion 32 arranged on the connecting sleeve 15, and the second limiting structure 40 comprises a first sliding member 41 arranged on the outer circumferential surface of the core wire 20 near the proximal end, and a second sliding member 42 arranged on the outer circumferential surface of the core wire in the middle region.

[0105] The first sliding member 41 is in sliding cooperation with the first limiting portion 31, the first sliding member 41 can slide on the first limiting portion 31 in the axial direction of the core wire, and the first limiting portion 31 limits the rotation of the first sliding member 41 relative to the sleeve assembly in the circumferential direction of the core wire; the second sliding member 42 is in sliding cooperation with the second limiting portion 32, the second sliding member 42 can slide on the second limiting portion 32 in the axial direction of the core wire, and the second limiting portion 32 limits the rotation of the second sliding member 42 relative to the sleeve assembly in the circumferential direction of the core wire. During the intervention of the target blood vessel or the bending adjustment, the rotation of the core wire 20 relative to the bending tube 12 is prevented, the large shear stress generated at the distal end of the core wire 20 due to the torsion is reduced, and the probability of the core wire breaking is reduced, thereby improving the reliability of the adjustable bending guide wire.

[0106] It should be emphasized that, in the embodiment, the first sliding member 41 and the second sliding member 42 are arranged at intervals in the axial direction of the core wire 20, and the first limiting portion 31 and the second limiting portion 32 are arranged on the support tube 11 and the connecting sleeve 15 respectively, which is conducive to further reducing the probability of the rotation of the core wire 20 relative to the bending tube 12 during the intervention of the target blood vessel or the bending adjustment.

[0107] Specifically, as shown in Figure 5 , Figure 13 and Figure 14 , the second limiting portion 32 is configured as a third sliding groove 321 arranged in the wall of the connecting sleeve 15, the third sliding groove 321 is a through groove arranged in the connecting sleeve 15, and the third sliding groove 321 extends from the proximal end to the distal end of the connecting sleeve 15. The second sliding member 42 is a long rod-shaped member, the second sliding member 42 extends in the axial direction of the core wire 20 and is connected to the outer circumferential surface of the core wire 20 by welding or gluing, the second sliding member 42 is slidably inserted into the third sliding groove 321, so that the second sliding member 42 can slide relative to the support tube 11 in the axial direction of the core wire in the third sliding groove 321, and the inner walls on both sides of the third sliding groove 321 in the circumferential direction of the connecting sleeve 15 are used to limit the rotation of the second sliding member 42 relative to the connecting sleeve 15 in the circumferential direction of the core wire 20.

[0108] Generally, the axial distance between the connecting sleeve 15 and the distal end of the core wire 20 is smaller than the axial distance between the connecting sleeve 15 and the proximal end of the core wire 20. A structure restricting circumferential rotation is provided closer to the distal end. Specifically, a second limiting part 32 is provided on the connecting sleeve 15, and a second sliding member 42 is provided on the core wire that slides in cooperation with the second limiting part 32. The second limiting part 32 restricts the rotation of the second sliding member 42 in the circumferential direction of the core wire 20, which is more effective in preventing relative rotation between the distal end of the core wire 20 and the bending tube 12, reducing the large shear stress generated by torsion at the distal end of the core wire 20, thereby reducing the probability of core wire breakage and improving the reliability of the adjustable bending guide wire. Furthermore, a structure restricting circumferential rotation is also provided closer to the proximal end, specifically, a first sliding member 41 slides in cooperation with the first limiting part 31. That is, structures restricting circumferential rotation are simultaneously provided at both the distal and proximal ends, greatly reducing the probability of core wire breakage and improving the reliability of the adjustable bending guide wire.

[0109] Example 4

[0110] The differences between Embodiment 4 and Embodiments 3 and 2 will be described below. The similarities or similarities between Embodiment 4 and Embodiments 3 and 2 will not be repeated here.

[0111] In this embodiment, as Figure 6 As shown, the adjustable guide wire 100 includes a support tube 11, a transition tube 13, an adjusting tube 12, a core wire 20, a connecting sleeve 15, a first developing element 16, and a second developing element 17.

[0112] The distal end of the support tube 11 and the proximal end of the transition tube 13 do not directly abut against each other, but are spaced apart. In this embodiment, the length of the connecting sleeve 15 is longer than that of the connecting sleeve 15 in embodiment three, and the length of the connecting sleeve 15 ranges from 2mm to 100mm. A first imaging element 16 is installed over the connecting sleeve 15, and the first imaging element 16 is located between the support tube 11 and the transition tube 13. The degree of bending at the connection between the support tube 11 and the transition tube 13 can be observed through the first imaging element 16. When the bending angle at the connection between the support tube 11 and the transition tube 13 is large, the interventional operation can be terminated in time to prevent the bending angle at the connection between the support tube 11 and the transition tube 13 from exceeding the limit value and causing the adjustable guide wire 100 to break, thereby reducing the surgical risk.

[0113] In some embodiments, the outer diameters of the support tube 11, the first imaging element 16, the transition tube 13, and the second imaging element 17 are equal, making the outer peripheral surface of the adjustable guidewire 100 smooth and without protrusions, which is beneficial for the adjustable guidewire 100 to move more smoothly in the blood vessel.

[0114] It should be noted that due to the difference in bending performance of the support tube 11 and the transition tube 13, stress concentration is easily generated at the connection between the support tube 11 and the transition tube 13, which causes sharp bending deformation of the connection between the support tube 11 and the transition tube 13, and easily leads to the fracture of the connection between the support tube 11 and the transition tube 13. By lengthening the length of the connecting sleeve 15, the connecting sleeve 15 can lengthen the weak area between the connection between the support tube 11 and the transition tube 13, which is prone to deformation, so as to uniformly distribute the deformation and avoid excessive deformation of the connection between the distal end of the support tube 11 and the proximal end of the transition tube 13, thereby reducing the probability of bending fracture of the adjustable bending guide wire 100.

[0115] In other embodiments, the first developing member 16 and / or the second developing member 17 can also not be additionally provided, and the connecting sleeve 15 and the bending adjustment tube 12 themselves have developing properties, for example, the connecting sleeve 15 and the bending adjustment tube 12 can be a metal material with developing properties.

[0116] In the embodiment, as shown in Figure 7 , the first limiting structure 30 includes a first limiting portion 31 provided on the support tube 11 and a second limiting portion 32 provided on the connecting sleeve 15, and the second limiting structure 40 includes a first sliding member 41 provided on the outer circumferential surface of the core wire 20 close to the proximal end, and further includes a second sliding member 42 provided on the outer circumferential surface of the core wire in the middle region.

[0117] The first sliding member 41 and the first limiting portion 31 are in sliding cooperation, the first sliding member 41 can slide on the first limiting portion 31 in the axial direction of the core wire, and the first limiting portion 31 limits the first sliding member 41 from rotating relative to the sleeve assembly in the circumferential direction of the core wire; the second sliding member 42 and the second limiting portion 32 are in sliding cooperation, the second sliding member 42 can slide on the second limiting portion 32 in the axial direction of the core wire, and the second limiting portion 32 limits the second sliding member 42 from rotating relative to the sleeve assembly in the circumferential direction of the core wire. In the process of interventional target blood vessel or bending adjustment, the adjustable bending guide wire prevents the core wire 20 from rotating relative to the bending adjustment tube 12, reduces the large shear stress generated by the torsion of the distal end of the core wire 20, and further reduces the probability of fracture of the core wire, thereby improving the reliability of the adjustable bending guide wire.

[0118] It should be emphasized that in the embodiment, the first sliding member 41 and the second sliding member 42 are arranged at intervals in the axial direction of the core wire 20, and the first limiting portion 31 and the second limiting portion 32 are arranged on the support tube 11 and the connecting sleeve 15 respectively, which is conducive to further reducing the probability of the core wire 20 rotating relative to the bending adjustment tube 12 in the process of interventional target blood vessel or bending adjustment.

[0119] Specifically, please refer to Figure 7 , Figure 13 and Figure 14As shown, the second limiting part 32 is configured as a third sliding groove 321 opened in the pipe wall of the connecting sleeve 15, the third sliding groove 321 is a through groove opened in the connecting sleeve 15, and the third sliding groove 321 extends from the proximal end to the distal end of the connecting sleeve 15. The second sliding part 42 is a long strip-shaped rod, which extends along the axial direction of the core wire 20 and is connected to the outer circumferential surface of the core wire 20 by welding or gluing, and is slidably inserted into the third sliding groove 321, so that the second sliding part 42 can slide in the third sliding groove 321 relative to the support tube 11 along the axial direction of the core wire, and the two side inner walls of the third sliding groove 321 along the radial direction of the connecting sleeve 15 are used to limit the rotation of the second sliding part 42 relative to the connecting sleeve 15 along the circumferential direction of the core wire 20.

[0120] Generally, the axial distance between the connecting sleeve 15 and the distal end of the core wire 20 is less than the axial distance between the connecting sleeve 15 and the proximal end of the core wire 20, and the structure for limiting the circumferential rotation is arranged at a position closer to the distal end, specifically, the second limiting part 32 is arranged on the connecting sleeve 15, and the second sliding part 42 is arranged on the core wire 20 in sliding cooperation with the second limiting part 32, and the second limiting part 32 is used to limit the rotation of the second sliding part 42 along the circumferential direction of the core wire 20, which is more conducive to preventing the relative rotation between the distal end of the core wire 20 and the bending tube 12, reducing the large shear stress generated by the torsion of the distal end of the core wire 20, and further reducing the probability of fracture of the core wire and improving the reliability of the adjustable bending guide wire. Moreover, the structure for limiting the circumferential rotation is also arranged at a position closer to the proximal end, specifically, the first sliding part 41 is in sliding cooperation with the first limiting part 31, that is, the structure for limiting the circumferential rotation is arranged at a position closer to the distal end and a position closer to the proximal end at the same time, thereby greatly reducing the probability of fracture of the core wire and improving the reliability of the adjustable bending guide wire.

[0121] Embodiment Five

[0122] Hereinafter, the differences between Embodiment Five and Embodiment One, Embodiment Two, Embodiment Three and Embodiment Four will be described, and the same or similar parts between Embodiment Five and Embodiment One, Embodiment Two, Embodiment Three and Embodiment Four will not be described here.

[0123] In this embodiment, as shown, Figure 8 from the proximal end to the distal end, the bending tube 12 includes a proximal support section 121, a bending section 122 and a head end section 123 connected in sequence, and the bending performance of the bending section 122 is higher than that of the proximal support section 121 and the head end section 123.

[0124] In the embodiment, the proximal support section 121 has better support relative to the bending section 122, so that the proximal support section 121 has certain support and flexibility, which can keep certain softness, facilitate deformation according to the blood vessel shape, and not damage the blood vessel, and the proximal support section 121 can keep a small bending degree when the bending section 122 bends. The bending section 122 is more likely to bend relatively due to its better flexibility.

[0125] In some embodiments, the proximal support section 121, the bending section 122 and the head end section 123 are made of different materials, and the material of the bending section 122 has better flexibility than the materials of the proximal support section 121 and the head end section 123.

[0126] In some embodiments, the proximal support section 121, the bending section 122 and the head end section 123 are made of the same material, the cross-sectional area of the bending section 122 is smaller than the cross-sectional area of the proximal support section 121, and the cross-sectional area of the bending section 122 is smaller than the cross-sectional area of the head end section 123, so that the bending section 122 has better flexibility relative to the proximal support section 121 and the head end section 123.

[0127] In some embodiments, the bending section 122 has a first side and a second side respectively located on two sides of the axis of the adjustable bending tube 12, at least one cut 1221 is arranged on the tube wall of the first side of the adjustable bending tube 12, and the cut 1221 is arranged on the first side relative to the axis of the adjustable bending tube 12, so that the tube wall material of the first side of the adjustable bending tube 12 is less than the tube wall material of the second side. Therefore, when the core wire 20 is pulled, the adjustable bending tube 12 bends from the second side to the first side, so that the first side is located on the inside of the adjustable bending tube 12, and the second side is located on the outside of the adjustable bending tube 12, so as to ensure that the head end of the adjustable bending guide wire 100 can bend and deform in a specific direction when the core wire 20 is pulled, improve the certainty of the bending direction of the head end of the adjustable bending guide wire 100, and optimize the operability of the adjustable bending guide wire 100 in the process of interventional target blood vessels.

[0128] It can be understood that, in some exemplary embodiments, as shown in Figure 8 , the bending section 122 is provided with one cut 1221, and the length of the cut 1221 extends in the axial direction.

[0129] Embodiment Six

[0130] The differences between Embodiment Six and Embodiment Five will be described below, and the same or similar parts of Embodiment Six and Embodiment Five will not be described here.

[0131] In the embodiment, please refer to Figure 9 , Figure 10 and Figure 11As shown, in the direction from the proximal end to the distal end, the adjustable bending tube 12 comprises a proximal support section 121 and a bending section 122 connected in sequence, and the bending performance of the bending section 122 is higher than that of the proximal support section 121.

[0132] In this embodiment, the proximal support section 121 has better support performance relative to the bending section 122, so that the proximal support section 121 has certain support performance and flexibility, which can not only maintain certain softness to facilitate deformation in accordance with the shape of the blood vessel and not damage the blood vessel, but also can maintain a smaller bending degree when the bending section 122 is bent. The bending section 122 is more likely to bend relatively due to its better flexibility.

[0133] The bending section 122 has a first side and a second side located on both sides of the axis of the adjustable bending tube 12, respectively, and a plurality of cutouts 1221 are arranged on the tube wall of the bending section 122 of the adjustable bending tube 12, which are arranged in sequence in the axial direction and form openings towards the same side, that is, each cutout 1221 forms an opening towards the first side of the adjustable bending tube 12, respectively.

[0134] Specifically, please refer to Figure 9 , Figure 10 and Figure 22 , Figure 23 , Figure 24 and Figure 25 , the cutout 1221 comprises a first cutout section 12211 and a second cutout section 12212 extending in the axial direction of the adjustable bending tube 12, and the first cutout section 12211 and the second cutout section 12212 are arranged in the circumferential direction of the adjustable bending tube 12. The cutout 1221 further comprises a third cutout section 12213, and the two ends of the third cutout section 12213 are connected to the proximal side of the first cutout section 12211 and the proximal side of the second cutout section 12212, respectively. In this embodiment, the connection between the third cutout section 12213 and the first cutout section 12211 and the second cutout section 12212 is smoothly transitioned in the form of a circular arc, wherein the third cutout section 12213 is located on the tube wall of the first side of the bending section 122, and the third cutout section 12213 forms a gap in the tube wall of the first side of the bending section 122, so that the tube wall material of the first side of the adjustable bending tube 12 is less than that of the second side. Therefore, when subjected to the tension of the core wire 20, the adjustable bending tube 12 bends in the direction from the second side to the first side, so that the first side is located on the inner arc side of the adjustable bending tube 12, and the second side is located on the outer arc side of the adjustable bending tube 12, so as to ensure that the head end of the adjustable bending guide wire 100 can bend and deform in a specific direction when the core wire 20 is pulled, improve the certainty of the bending direction of the head end of the adjustable bending guide wire 100, and optimize the operability of the adjustable bending guide wire 100 in the process of interventional target blood vessels. In other embodiments, please refer to Figure 11 , the connection between the third cutout section 12213 and the first cutout section 12211 and the second cutout section 12212 can also be arranged in the form of a right angle.

[0135] The above arrangement can make the bending section 122 have both good flexibility and small minimum bending radius. The good flexibility can make the bending section 122 pass through the body better, and the small minimum bending radius can make the bending section 122 have more delicate bending action, so that the operation is more delicate and the operability is stronger. In the embodiment, the plurality of cutouts 1221 divide the bending section 122 into a plurality of ring structures 1220 on the first side and a plurality of connecting arms 12201 on the second side. Due to the arrangement of the first cutout section 12211, the second cutout section 12212 and the third cutout section 12213, each ring structure 1220 includes an axially connected ring first part M and a ring second part N, wherein the ring first part M is connected with the connecting arm 12201, and the ring second part N is not connected with the connecting arm 12201. It can be understood that the flexibility depends on the connecting arm 12201 and the ring first part M, wherein the smaller the width a of the connecting arm 12201 and / or the width c of the ring first part M, the better the flexibility, and vice versa. The minimum bending radius depends on the distance b between adjacent ring structures 1220, wherein the smaller the distance b between adjacent ring structures 1220, the smaller the minimum bending radius, and vice versa.

[0136] In the embodiment, each ring structure 1220 only has the ring first part M connected with the connecting arm 12201, and the ring second part N is not connected with the connecting arm 12201, so as to reduce the width connected with the connecting arm 12201, that is, to reduce the width c of the ring first part M, so as to have better flexibility. In addition, the distance b between adjacent ring structures 1220 is shortened due to the existence of the ring second part N not connected with the connecting arm 12201, so as to make the minimum bending radius smaller, so as to realize that the bending section 122 has both good flexibility and small minimum bending radius. Further, referring to Figure 25 , the minimum circumferential length a' between the first cutout section 12211 and the second cutout section 12212 is smaller than half the circumference of the bending tube 12, and the circumferential length of the third cutout section 12213 is greater than half the circumference of the bending tube 12, so as to make the width a of the connecting arm 12201 between the first cutout section 12211 and the second cutout section 12212 smaller, and further enhance the flexibility of the bending section 122.

[0137] Further, as shown in Figure 11 , when the bending section 122 is bent to a certain extent, the plurality of tube walls on the first side of the third cutout section 12213 interfere with each other due to deformation, so as to prevent the bending section 122 from being further bent, so as to limit the minimum bending radius of the distal end of the bending section 122.

[0138] Embodiment Seven

[0139] Embodiment seven is to describe various structural schemes of the first limiting part 31 and the first sliding part 41, and any one of the technical schemes in the various structural schemes proposed in this embodiment can be combined with any one of Embodiments one to six, and the technical scheme of this embodiment combined with any one of Embodiments one to six can also be covered within the protection scope of the present application.

[0140] As shown in Figure 15 According to one embodiment of the present application, the first limiting part 31 is configured as a first sliding groove 311 opened on the pipe wall of the support tube 11, the length direction of the first sliding groove 311 extends along the axial direction of the support tube 11, and the proximal end of the first sliding groove 311 extends to the proximal end of the support tube 11 and forms a first opening 312 at the proximal end of the support tube 11, the first sliding groove 311 is a through groove, and the first sliding groove 311 penetrates the inner side surface and the outer peripheral surface of the pipe wall of the support tube along the radial direction of the support tube 11. The first sliding part 41 extends along the axial direction of the core wire and is connected to the outer peripheral surface of the core wire by welding or gluing, the first sliding part 41 is slidably inserted into the first sliding groove 311, so that the first sliding part 41 can slide in the first sliding groove 311 relative to the support tube 11 along the axial direction of the core wire, and the two side walls of the first sliding groove 311 along the circumferential direction of the support tube are used to limit the rotation of the first sliding part 41 relative to the support tube 11 along the circumferential direction of the core wire 20.

[0141] When the first sliding part 41 moves in the distal direction in the first sliding groove 311, when the distal end of the first sliding part 41 abuts against the inner wall of the distal end of the first sliding groove 311, the first sliding groove 311 can prevent the first sliding part 41 from continuing to move distally, thereby limiting the axial displacement of the core wire in the distal direction to a certain extent, preventing the core wire from being pushed distally, and preventing excessive displacement from causing the development spring or the bending tube to be disconnected and fall off.

[0142] In this embodiment, the cross-sectional shape of the first sliding part 41 in the radial direction can be circular, elliptical, rectangular, or wedge-shaped.

[0143] As shown in Figure 16As shown, according to another embodiment of the present application, the first limiting part 31 is configured as a first sliding groove 311 formed on the tube wall of the support tube 11, the length direction of the first sliding groove 311 extends along the axial direction of the support tube 11, and the proximal end of the first sliding groove 311 extends to the proximal end of the support tube 11 and forms a first opening 312 at the proximal end of the support tube 11, the first sliding groove 311 is a through groove, and the first sliding groove 311 penetrates the inner side surface and the outer peripheral surface of the tube wall of the support tube 11 along the radial direction of the support tube 11. The first sliding member includes a sliding part 411 and a first stop part 412 connected to each other, the sliding part 411 is configured as a long strip structure, the distal end of the sliding part 411 is inserted into the first sliding groove 311, the proximal end of the sliding part 411 extends out of the first sliding groove through the first opening 412, and the first stop part 412 is configured as a tubular structure, the first stop part 412 is sleeved outside the core wire 20, and the first stop part 412 is connected to the core wire in an integrated manner through welding or gluing.

[0144] When the first sliding member 41 moves in the distal end direction in the first sliding groove 311, when the distal end of the first stop part 412 can abut against the proximal end of the support tube 11, the continuous movement of the first sliding member 41 in the distal end direction is prevented, the axial displacement of the core wire in the distal end direction is limited to a certain extent, and the over displacement of the core wire when it is pushed in the distal end direction is prevented, which can cause the connection of the developing spring or the bending tube to fail and fall off.

[0145] It should be noted that the first stop part 412 is not limited to the tubular structure, and in other embodiments, as long as the size of the first stop part 412 along the circumferential direction of the support tube 11 is greater than the size of the first opening along the circumferential direction of the support tube 11, the first stop part 412 can abut against the proximal end of the support tube 11 to limit the axial displacement distance of the core wire in the distal end direction, and the over displacement of the core wire when it is pushed in the distal end direction is prevented, which can cause the connection of the developing spring or the bending tube to fail and fall off.

[0146] As shown in FIG. 6, the first sliding member 41 is connected to the core wire 20 through the first stop part 412, and the first sliding member 41 is connected to the support tube 11 through the sliding part 411. Figure 18 and Figure 19As shown, according to another embodiment of the present application, the first limiting part 31 is configured as two first sliding grooves 311 respectively formed on the two sidewalls of the support tube 11, the length direction of the first sliding grooves 311 extends along the axial direction of the support tube 11, and the proximal end of the first sliding grooves 311 extends to the proximal end of the support tube 11 and forms a first opening 312 at the proximal end of the support tube 11, the first sliding grooves 311 are through grooves, and the first sliding grooves 311 respectively penetrate the inner and outer surfaces of the sidewalls of the support tube 11 along the radial direction of the support tube 11. The first sliding part 41 is configured as a flat structure processed at the proximal end of the core wire 20, the two ends of the first sliding part 41 along the radial direction of the core wire 20 protrude from the outer circumferential surface of the core wire 20 and are respectively inserted into the two first sliding grooves 311, so that the first sliding part 41 can move relative to the support tube 11 along the axial direction of the core wire 20 in the first sliding grooves 311, and the two sidewalls of the first sliding grooves 311 along the circumferential direction of the support tube 11 are used to limit the rotation of the first sliding part 41 relative to the support tube 11 along the circumferential direction of the core wire 20.

[0147] In this embodiment, the first sliding part 41 and the core wire 20 are integrally formed, without the need for welding operation, and the process is simple, and based on the integrated structure, the risk of the first sliding part falling off from the core wire is avoided, and the reliability is higher.

[0148] As shown, Figure 17 As shown, according to another embodiment of the present application, the first limiting part 31 is configured as two first sliding grooves 311 respectively formed on the two sidewalls of the support tube 11, the length direction of the first sliding grooves 311 extends along the axial direction of the support tube 11, and the proximal end of the first sliding grooves 311 extends to the proximal end of the support tube 11 and forms a first opening 312 at the proximal end of the support tube 11, the first sliding grooves 311 are through grooves, and the first sliding grooves 311 respectively penetrate the inner and outer surfaces of the sidewalls of the support tube 11 along the radial direction of the support tube 11. The first sliding part 41 is configured as a flat structure processed at the proximal end of the core wire 20, the two ends of the first sliding part 41 along the radial direction of the core wire 20 protrude from the outer circumferential surface of the core wire 20 and are respectively inserted into the two first sliding grooves 311, so that the first sliding part 41 can move relative to the support tube 11 along the axial direction of the core wire 20 in the first sliding grooves 311, and the two sidewalls of the first sliding grooves 311 along the circumferential direction of the support tube 11 are used to limit the rotation of the first sliding part 41 relative to the support tube 11 along the circumferential direction of the core wire 20.

[0149] Further, the distal end of the second sliding groove 413 is provided with a necked part 4131, the proximal end of the first limiting part 31 is provided with a second stop part 313, the size of the second stop part 313 along the circumferential direction of the core wire is greater than the size of the necked part 4131 along the circumferential direction of the core wire, so that the distal end of the second stop part 313 can abut against the proximal end of the necked part.

[0150] In the embodiment, when the first sliding member 41 moves in the distal direction, the distal end of the first sliding member 41 can abut against the proximal end of the support tube 11, thereby preventing the first sliding member 41 from continuing to move distally, and limiting the axial displacement of the core wire in the distal direction, so as to prevent the core wire from being excessively displaced when being pushed distally, and causing the development spring or the bending tube to be disconnected and fall off. In addition, when the first sliding member 41 moves in the proximal direction, the distal end of the second stop portion 313 can abut against the proximal end of the closing portion 4131, thereby preventing the first sliding member 41 from continuing to move proximally, and limiting the axial displacement of the core wire in the proximal direction, so as to prevent the core wire from being excessively displaced when being pushed proximally, and causing the development spring or the bending tube to be disconnected and fall off.

[0151] Embodiment Eight

[0152] Embodiment Eight is to describe a structure scheme of the core wire. It is emphasized that the core wire structure in the embodiment can be replaced by the core wire structure described in any one of Embodiments One to Seven. The structure in the technical scheme of the embodiment except the core wire can be combined with any one of Embodiments One to Seven. The technical scheme of the embodiment combined with any one of Embodiments One to Seven also falls within the protection scope of the present application.

[0153] As shown in Figure 20 the core wire 20 includes a distal end portion 230 and a proximal end portion 210 connected together. The distal end portion 230 includes a first segment 231 and a second segment 232 connected to the proximal end of the first segment 231. The distal end of the first segment 231 is connected to the bending tube 12. In the direction from the proximal end to the distal end, the diameter of the second segment 232 gradually decreases, and the minimum diameter of the second segment 232 is greater than or equal to the diameter of the first segment 231.

[0154] Based on the structure of the core wire 20 in the embodiment, the first segment 231 is a soft segment, and the first segment 231 has better flexibility than the second segment 232. In the process of interventional target blood vessels, it is beneficial to make the head end of the adjustable bending guide wire bend more smoothly to adapt to the shape of the blood vessels, and reduce the risk of damage to the blood vessels during the intervention process.

[0155] The diameter of the second segment 232 is greater than the diameter of the first segment 231, so that the second segment 232 has better support than the first segment 231, and the stiffness of the core wire of the second segment 232 is improved, which is used to offset the warping of the non-bending region in the second segment 232 when the adjustable bending guide wire is bent. In the embodiment, the non-bending region in the second segment 232 includes a region other than the distal end portion of the first transition segment 2321 and the first segment 231.

[0156] Understandably, from the distal end to the proximal end, as the diameter of the second segment 232 gradually increases, the support force of the core wire of the second segment 232 gradually increases with the increase in diameter, while retaining a certain degree of flexibility, thereby improving the pushing ability and tracking performance of the second segment 232.

[0157] Furthermore, the second segment 232 includes multiple sequentially connected transition segments. From the distal end to the proximal end, the tapers of any two adjacent transition segments are not equal, resulting in different bending and support properties for each transition segment. Furthermore, from the distal end to the proximal end, the bending properties of each transition segment gradually decrease. However, due to the unequal tapers of two adjacent transition segments, the bending properties of each transition segment do not decrease uniformly. Based on the needs of different regions, the bending or support properties of each transition segment are given some emphasis, thereby improving the operability of the adjustable guidewire.

[0158] Taper refers to the ratio of the diameter of the base of a cone to its height. Each transition segment constitutes a segment of a cone shape with a different taper. The larger the taper, the greater the decrease in diameter of the transition segment per unit distance from the proximal end to the distal end. Conversely, the smaller the taper, the smaller the decrease in diameter of the transition segment per unit distance from the proximal end to the distal end.

[0159] In this embodiment, from the distal end to the proximal end, the second segment 232 includes a first transition segment 2321, a second transition segment 2322, a third transition segment 2323, and a fourth transition segment 2324 connected in sequence. The taper of the first transition segment 2321 is greater than that of the second transition segment 2322, the taper of the second transition segment 2322 is greater than that of the third transition segment 2323, and the taper of the third transition segment 2323 is less than that of the fourth transition segment 2324.

[0160] Please combine Figure 20 and Figure 21 As shown, Figure 21 The dashed line in the figure represents the distal portion 230 of the core wire 20, whose diameter gradually decreases uniformly from the proximal end to the distal end. In this embodiment, the core wire structure differs from a core wire where the diameter of the distal portion 230 decreases uniformly from the proximal end to the distal end (e.g.,...). Figure 21(As shown by the dashed line), the distal portions of the first segment 231 and the first transition segment 2321 have smaller diameters, thus exhibiting better bending performance. Since the distal portion of the first transition segment 2321 is connected to the first segment 231, during the bending process of the first segment 231, the distal portion of the first transition segment 2321 will also bend. Therefore, the bending area includes the distal portion of the first transition segment 2321 and the first segment 231. In one embodiment, the distal portion 230 can be disposed inside the transition tube 13 and the bending tube 12, wherein the bending tube 12 can be configured to fit outside the distal portions of the first segment 231 and the first transition segment 2321; the proximal portion 210 can be disposed inside the support tube 11, and the shape of the proximal portion 210 can be further ground and shaped (see...). Figures 3-6 (Core wire structure inside the support tube 11). In one embodiment, when the transition tube 13 is not present, the bending tube 12 can be configured to be sleeved outside the distal portion of the first segment 231 and the first transition segment 2321, and the other parts of the core wire can be disposed inside the support tube 11.

[0161] Due to the tapered design of the parts of the first transition segment 2321 (excluding the distal portion), the second transition segment 2322 to the fourth transition segment 2324, and the core wire with a uniformly decreasing diameter (such as...) Figure 21 (As shown by the dashed line) has a larger diameter, and therefore provides better support.

[0162] The diameter and length range of each part of the distal portion 230 of the core wire are shown in Table 1:

[0163] Table 1

[0164]

[0165] The meaning of D (%) in Table 1 above is that D is the range of diameters of each segment from the start point to the end point. For example, if the diameter of the unground core wire (e.g., the proximal portion 210 of the core wire) is D, then the diameter of the first segment 231 is in the range of 0.15D to 0.3D. In the direction from the distal end to the proximal end, the diameters of the start point and the end point are in the range of 15-30. It is possible that the start diameter is 15 and the end diameter is 20; it is possible that the start diameter is 20 and the end diameter is 30. The start diameter is always ≤ the end diameter, and it is also possible that the start diameter is 20 and the end diameter is 20.

[0166] L refers to length; for example, the length of the first segment 231 is in the range of 2mm to 20mm.

[0167] The above merely describes preferred specific embodiments of the present application, but the protection scope of the present application is not limited thereto, any person skilled in the art can easily think of changes or replacements within the technical range disclosed by the present application, which should be covered in the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. An adjustable bend guide wire, comprising: The adjustable bending guide wire comprises: a sleeve assembly defining a receiving channel, the sleeve assembly comprising a bending tube defining at least a distal section of the receiving channel; a core wire arranged in the receiving channel, a distal end of the core wire being connected to the distal end or a position close to the distal end of the bending tube, and a proximal end of the core wire extending out of the receiving channel from a proximal end of the receiving channel; wherein the sleeve assembly is provided with a first limiting structure, the core wire is provided with a second limiting structure, and the first limiting structure and the second limiting structure are capable of axially moving relative to each other and are limited in circumferential movement relative to each other.

2. The adjustable bend guide wire of claim 1, wherein, The sleeve assembly further comprises a support tube in communication with the bending tube and defining a proximal section of the receiving channel; the first limiting structure comprises a first limiting portion provided on the support tube, and the second limiting structure comprises a first sliding member, the first limiting portion and the first sliding member being axially slidably connected and being limited in circumferential rotation relative to each other.

3. The adjustable bending guide wire according to claim 2, wherein the first limiting portion is configured as a first sliding groove formed on a tube wall of the support tube, the first sliding groove forming a first opening at a proximal end of the support tube; at least a portion of the first sliding member is configured to extend along an axial direction of the core wire, and the first sliding member is slidably arranged in the first sliding groove.

4. The adjustable bend guide wire of claim 3, wherein, the first sliding member comprises a sliding portion and a first stop portion connected to a proximal end of the sliding portion, a distal end of the sliding portion being arranged in the first sliding groove, and a proximal end of the sliding portion extending out of the first sliding groove from the first opening, a circumferential dimension of the first stop portion being greater than a circumferential dimension of the first opening, and a distal end of the first stop portion being capable of abutting against the proximal end of the support tube.

5. The adjustable bending guide wire according to claim 2, wherein the first sliding member is configured as a tubular member, the first sliding member being arranged outside the core wire, a tube wall of the first sliding member being provided with a second sliding groove, the second sliding groove forming a second opening at a distal end of the first sliding member; the first limiting portion is configured to extend along an axial direction of the support tube, a distal end of the first limiting portion being connected to the proximal end of the support tube, and a proximal end of the first limiting portion being slidably arranged in the second sliding groove through the second opening.

6. The adjustable bending guide wire according to claim 5, wherein a distal end of the second sliding groove is provided with a tapered portion, and a proximal end of the first limiting portion is provided with a second stop portion, a distal end of the second stop portion being capable of abutting against a proximal end of the tapered portion.

7. The adjustable bend guide wire of claim 2, wherein, The sleeve assembly further comprises: a transition tube defining an intermediate section of the receiving channel, a distal end of the transition tube being in communication with the bending tube, and a proximal end of the transition tube being in communication with the support tube; a connecting sleeve, a proximal end of the connecting sleeve being connected to the support tube, and a distal end of the connecting sleeve being connected to the transition tube, the core wire being movably arranged in the connecting sleeve.

8. The adjustable bending guide wire according to claim 7, wherein The first limiting structure comprises a second limiting part arranged on the connecting sleeve, and the second limiting structure comprises a second sliding member, the second limiting part and the second sliding member are axially slidably connected and are limited from rotating relative to each other in the circumferential direction. The second limiting part is configured as a third sliding groove arranged on the wall of the connecting sleeve, and the second sliding member is configured to extend along the axial direction of the core wire and is slidably arranged in the third sliding groove.

9. The adjustable bend guide wire of any of claims 1-8, wherein, The core wire comprises a distal end part connected to the bending pipe, the distal end part comprises a first segment and a second segment connected to the proximal end of the first segment, the diameter of the distal end part gradually decreases from the proximal end to the distal end, and the second segment comprises a plurality of transition segments connected in sequence, the taper of any two adjacent transition segments is not equal from the proximal end to the distal end.

10. The adjustable bend guide wire of claim 9, wherein, The second segment has a distal end part connected to the first segment, and the distal end part of the second segment and the first segment are arranged inside the bending pipe.

11. The adjustable bend guide wire of claim 1, wherein, The bending pipe comprises a bending segment, a plurality of cutouts are arranged on the wall of the bending segment, the plurality of cutouts are arranged in sequence along the axial direction and form openings towards the same side, wherein the cutouts comprise a first cutout segment and a second cutout segment arranged in the circumferential direction, the first cutout segment and the second cutout segment both extend along the axial direction, and the cutouts further comprise a third cutout segment, both ends of the third cutout segment are connected to the proximal end side of the first cutout segment and the proximal end side of the second cutout segment, respectively.

12. The adjustable bend guide wire of claim 11, wherein, The minimum circumferential length between the first cutout segment and the second cutout segment is less than half of the circumference of the bending pipe, and the circumferential length of the third cutout segment is greater than half of the circumference of the bending pipe.

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