Plasma mixing device
By designing a plasma mixing device that drives the clamping mechanism to rotate via a rotating shaft, the blood collection tubes can be rotated twice, solving the problem of low mixing efficiency in existing technologies and improving the mixing effect of plasma.
Patent Information
- Application Number
- CN202511649093.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-12
- Publication Date
- 2025-12-19
AI Technical Summary
Existing roller mixers are inefficient when mixing plasma products, making it difficult to improve mixing efficiency while maintaining quality stability.
A plasma mixing device was designed, which drives multiple clamping mechanisms to rotate via a rotating shaft, causing the blood collection tube to rotate simultaneously around the rotating shaft and its own axis. The mixing intensity is adjusted by combining the clamping components and the driving components to achieve a dual mixing mechanism for the plasma.
While ensuring the stability of plasma quality, it significantly improves the mixing efficiency, adapts to different mixing requirements, and enhances the mixing effect.
Smart Images

Figure CN121155397A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of medical devices, in particular to a blood plasma mixing device. BACKGROUND
[0002] In the preparation of certain blood products, there is a need for mixing blood plasma in hospital blood banks or related preparation rooms to ensure the uniformity and quality stability of blood plasma products.
[0003] In the prior art, the conventional roller-type mixing device is suitable for blood plasma products with high quality stability requirements, but its mixing method is single and the mixing efficiency is low. Therefore, how to design a new device to improve the mixing efficiency of blood plasma products while maintaining high quality stability is a problem that needs to be solved. SUMMARY
[0004] In view of the deficiencies in the prior art, the present application provides a blood plasma mixing device, which can solve or at least alleviate one or more of the above problems and other problems in the prior art.
[0005] The present application provides a blood plasma mixing device, comprising:
[0006] a rack;
[0007] a rotating shaft rotatably arranged on the rack;
[0008] a motor arranged on the rack, the output end of the motor being connected with the end of the rotating shaft; and
[0009] a plurality of clamping mechanisms distributed on the outer periphery of the rotating shaft and connected with the rotating shaft, the clamping mechanisms being used for clamping blood collection tubes loaded with blood plasma;
[0010] wherein the axis of the blood collection tube clamped in the clamping mechanism is located on the radial direction of the rotating shaft, the clamping mechanism can rotate by the rotation of the rotating shaft, and the rotation center line of the clamping mechanism is the axis of the blood collection tube.
[0011] Preferably, the rack comprises a mounting seat and a matching disc; the matching disc is fixedly connected with the mounting seat; a coaxial first hole is formed in the matching disc; the rotating shaft is gap-fitted with the first hole; and the motor is arranged on the mounting seat.
[0012] The clamping mechanism comprises:
[0013] a clamping cylinder, one end of the clamping cylinder being open, the other end of the clamping cylinder being closed and rotatably connected with the outer wall of the rotating shaft, and the axis of the clamping cylinder extending along the radial direction of the rotating shaft;
[0014] a clamping assembly arranged in the clamping cylinder, the clamping assembly being used to clamp the blood collection tube loaded with blood plasma and enable the axis of the blood collection tube to be collinear with the axis of the clamping cylinder;
[0015] a rotating ring which is axially slidably sleeved outside the clamping cylinder, the outer ring of the rotating ring abutting against the end face of the matching disc; and
[0016] a driving assembly which is used to drive the rotating ring to slide axially along the clamping cylinder and then remain stationary, and is also used to drive the blood collection tube on the clamping assembly to rotate and then remain stationary.
[0017] Preferably, two or more strip-shaped limiting grooves extending along the axial direction of the clamping cylinder are arranged on the side wall of the clamping cylinder; all the strip-shaped limiting grooves are circumferentially and evenly distributed about the axis of the clamping cylinder; a limiting block is connected to the inner wall of the rotating ring corresponding to the strip-shaped limiting grooves; the end of the limiting block away from the rotating ring is inserted into the corresponding strip-shaped limiting groove; the limiting block and the strip-shaped limiting groove slide along the axial direction of the clamping cylinder; a second hole extending along the axial direction of the clamping cylinder is arranged on the limiting block;
[0018] The driving assembly comprises:
[0019] a fixed seat located in the clamping cylinder, the fixed seat being connected to the bottom of the closed end of the clamping cylinder; and
[0020] a driving shaft, one end of the driving shaft being rotationally connected to the fixed seat, the other end of the driving shaft being located outside the open end of the clamping cylinder after passing through the second hole, the driving shaft being threadedly connected to the second hole.
[0021] Preferably, the clamping assembly comprises:
[0022] two mounting plates, the two mounting plates being oppositely arranged, the two mounting plates and the fixed seat being located on the diameter of the clamping cylinder;
[0023] a support cylinder, the lower end of the support cylinder being closed, the upper end of the support cylinder being open, the inner wall of the open end of the support cylinder being provided with an annular elastic ring used to fix the blood collection tube, the support cylinder being coaxial with the clamping cylinder, the support cylinder being located between the two mounting plates;
[0024] a first connecting rod, one end of the first connecting rod being connected to the outer wall of the support cylinder, the other end of the first connecting rod being rotationally connected to the mounting plate;
[0025] a second connecting rod, the second connecting rod being coaxial with the first connecting rod, one end of the second connecting rod being connected to the outer wall of the support cylinder, the other end of the second connecting rod being rotationally connected to the other mounting plate.
[0026] Preferably, the first connecting rod is provided with a first annular groove and a second annular groove in parallel.
[0027] The driving assembly further comprises:
[0028] A torsional spring is sleeved outside the second connecting rod, and two ends of the torsional spring are connected with the mounting cylinder and the mounting plate respectively;
[0029] A guide block is connected with the side surface of the mounting plate close to the first connecting rod, and the surface of the guide block away from the corresponding mounting plate is provided with an inclined guide surface;
[0030] An external connecting block is connected with the limiting block at one end, and the other end of the external connecting block extends in the transverse direction. The external connecting block is located at the rear side of the mounting plate, and a third hole is formed in the external connecting block;
[0031] A sliding block is slidingly connected with the third hole at one end, and the sliding direction of the sliding block is perpendicular to the axis of the clamping cylinder;
[0032] A third connecting rod is connected with the sliding block at one end, and the other end of the third connecting rod is abutted with the guide surface of the guide block. When the third connecting rod gradually moves away from the bottom of the clamping cylinder, it also gradually moves away from the corresponding mounting plate;
[0033] A first pulley is rotatably connected with the end of the third connecting rod away from the sliding block;
[0034] A second pulley is rotatably connected with the corresponding mounting plate, and the second pulley is located below the first connecting rod;
[0035] A third pulley is rotatably connected with the corresponding mounting plate, and the third pulley is located above the first connecting rod; and
[0036] A connecting rope is wound and connected in the first annular groove at one end, and the other end of the connecting rope is wound and connected in the second annular groove from the side of the first annular groove away from the first pulley, passes through the third pulley away from the first pulley, and then winds around the second pulley from the side of the second annular groove towards the first pulley.
[0037] Preferably, a plurality of mounting holes extending along the axial direction of the rotating shaft are formed on the end face of the rotating shaft away from the motor, and a plurality of strip-shaped notches corresponding to the mounting holes are also formed on the end face of the rotating shaft away from the motor, the strip-shaped notches extending along the axial direction of the rotating shaft, and the inner side of the strip-shaped notches being in communication with the mounting holes; the diameter of the mounting hole is greater than the width of the strip-shaped notch;
[0038] The clamping mechanism further comprises:
[0039] A connecting seat is rotatably connected to the closed end of the clamping cylinder, and the connecting seat is located between the clamping cylinder and the rotating shaft;
[0040] A connecting block is connected to one end of the connecting seat away from the clamping cylinder, and the end of the connecting block away from the connecting seat can pass through the strip-shaped notch;
[0041] A positioning column is in axial sliding fit with the mounting hole, and the positioning column is connected to the end of the connecting block away from the connecting seat;
[0042] A fixing cover is detachably connected to the end of the rotating shaft; and
[0043] A plurality of elastic telescopic rods are connected to the fixing cover, the elastic telescopic rods correspond to the mounting holes, and the elastic telescopic rods can be inserted into the mounting holes and abut against the corresponding positioning columns.
[0044] Compared with the prior art, the present application has the following beneficial effects:
[0045] In the present application, the rotating shaft is rotated to drive the plurality of clamping mechanisms on the outer periphery of the rotating shaft to rotate, and the plurality of clamping mechanisms are further rotated by the rotating shaft to realize self-rotation, so that the blood collection tubes in the clamping mechanisms rotate around the axis of the rotating shaft and also self-rotate around their own axes, thereby improving the mixing efficiency while ensuring high quality stability of the plasma. BRIEF DESCRIPTION OF DRAWINGS
[0046] In order to more clearly illustrate the specific embodiments of the present application or the technical solutions in the prior art, the following will briefly introduce the drawings needed to be used in the specific embodiments or prior art description. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, various elements or parts are not necessarily drawn according to the actual proportions.
[0047] Figure 1 It is a perspective view of a blood plasma mixing device according to an embodiment of the present application;
[0048] Figure 2 It is a perspective view of a clamping mechanism cooperating with a rotating shaft and a cooperating disc in the blood plasma mixing device; Figure 1 in the blood plasma mixing device;
[0049] Figure 3 for Figure 2 Another 3D view (only one clamping mechanism is retained);
[0050] Figure 4 for Figure 3 A sectional view;
[0051] Figure 5 for Figure 4 Enlarged view of point A in the middle;
[0052] Figure 6 for Figure 4 Enlarged view at point B in the middle;
[0053] Figure 7 for Figure 3 A partial exploded view;
[0054] Figure 8 for Figure 7 Another 3D image;
[0055] Figure 9 for Figure 3 Enlarged view of the clamping mechanism;
[0056] Figure 10 for Figure 9 Another 3D view (the wall of the hidden clamping cylinder);
[0057] Figure 11 for Figure 10 Another 3D image;
[0058] Figure 12 for Figure 11 A schematic diagram showing the connection between the first, second, and third pulleys and the connecting rope.
[0059] Figure label:
[0060] 10. Frame; 11. Mounting base; 12. Mating plate; 121. First hole;
[0061] 20. Shaft; 21. Mounting hole; 22. Strip-shaped notch;
[0062] 30. Electric motor;
[0063] 40. Clamping mechanism; 41. Clamping cylinder; 411. Strip-shaped limiting groove; 42. Clamping assembly; 421. Mounting plate; 422. Support cylinder; 423. Annular elastic ring; 424. First connecting rod; 425. Second connecting rod; 426. First annular groove; 427. Second annular groove; 43. Rotating ring; 431. Limiting block; 432. Second hole; 44. Drive assembly; 441. Fixed seat; 442. Drive shaft; 443. Torsion spring; 444. Guide block; 445. External block; 446. Third hole; 447. Slider; 448. Third connecting rod; 449. First pulley; 450. Second pulley; 451. Third pulley; 452. Connecting rope; 46. Connecting seat; 47. Connecting block; 48. Positioning post; 49. Fixed cover;
[0064] 50. Elastic telescopic rod; 51. First sleeve; 52. Second sleeve; 53. Spring;
[0065] 60. Blood collection tubes. Detailed Implementation
[0066] The embodiments of the technical solution of the present invention will now be described in detail with reference to the accompanying drawings. These embodiments are merely illustrative of the technical solution of the present invention and are therefore intended to limit the scope of protection of the present invention.
[0067] It should be noted that, unless otherwise stated, the technical or scientific terms used in this application should have the ordinary meaning as understood by one of ordinary skill in the art to which this invention pertains.
[0068] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.
[0069] Furthermore, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly defined.
[0070] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.
[0071] In this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.
[0072] See Figures 1 to 12 This embodiment provides a plasma mixing device, including: a frame 10, a rotating shaft 20, a motor 30, and multiple clamping mechanisms 40.
[0073] A rotating shaft 20 is rotatably mounted on a frame 10, and a motor 30 is mounted on the frame 10. The output end of the motor 30 is connected to the end of the rotating shaft 20. Specifically, the output end of the motor 30 can be directly connected to the end of the rotating shaft 20, or it can be connected to the end of the rotating shaft 20 through gears or gear sets, or in other ways. Multiple clamping mechanisms 40 are distributed around the outer periphery of the rotating shaft 20 and connected to the rotating shaft 20. The clamping mechanisms 40 are used to clamp blood collection tubes 60 containing plasma. The axis of the blood collection tube 60 clamped by the clamping mechanism 40 is located radially on the rotating shaft 20. The clamping mechanism 40 can rotate by means of the rotation of the rotating shaft 20, and the rotation center line of the clamping mechanism 40 is the axis of the blood collection tube 60.
[0074] In this embodiment, the motor 30 drives the rotating shaft 20 to rotate at a low speed, selectable between 0.2 revolutions per second and 1 revolution per second. The rotation of the rotating shaft 20 drives the multiple clamping mechanisms 40 around its outer periphery to rotate; simultaneously, the multiple clamping mechanisms 40 rotate on their own axes due to the rotation of the rotating shaft 20. This causes the blood collection tube 60 within the clamping mechanisms 40 to rotate around the axis of the rotating shaft 20 while also rotating on its own axis. During this process, the plasma in the blood collection tube 60, besides being moved circumferentially along the inner wall of the blood collection tube 60 by the shaft's movement, also moves back and forth between the two ends of the blood collection tube 60 (one rotation of the rotating shaft 20 corresponds to one back-and-forth movement of the plasma between the two ends of the blood collection tube 60). This dual mixing mechanism ensures that the plasma is thoroughly mixed in a gentler movement under the low-speed rotation of the rotating shaft 20, resulting in higher mixing efficiency. In other words, mixing efficiency is improved while maintaining high plasma quality stability (preserving cell integrity).
[0075] In one embodiment, the frame 10 includes a mounting base 11 and a mating plate 12. The mating plate 12 is fixedly connected to the mounting base 11. A coaxial first hole 121 is opened on the mating plate 12. The rotating shaft 20 is clearance-fitted with the first hole 121. The motor 30 is mounted on the mounting base 11.
[0076] The clamping mechanism 40 includes: a clamping cylinder 41, a clamping assembly 42, a rotating ring 43, and a drive assembly 44.
[0077] One end of the clamping cylinder 41 is open, and the other end is closed and rotatably connected to the outer wall of the rotating shaft 20. The axis of the clamping cylinder 41 extends radially along the rotating shaft 20. A detachable cover can also be connected to the open end of the clamping cylinder 41, and the detachability can be a snap-fit connection.
[0078] A clamping assembly 42 is disposed inside a clamping cylinder 41. The clamping assembly 42 is used to clamp a blood collection tube 60 containing plasma, ensuring that the axis of the blood collection tube 60 is collinear with the axis of the clamping cylinder 41. A rotating ring 43 is slidably sleeved on the outside of the clamping cylinder 41 along its axial direction, with the outer ring of the rotating ring 43 abutting against the end face of the mating disc 12. A driving assembly 44 is used to drive the rotating ring 43 to slide along the axial direction of the clamping cylinder 41 and then remain stationary. The driving assembly 44 is also used to drive the blood collection tube 60 on the clamping assembly 42 to rotate and then remain stationary.
[0079] In this embodiment, the blood collection tube 60, filled with plasma, is inserted into the clamping assembly 42 from the open end of the clamping cylinder 41. The rotating shaft 20 rotates, causing the clamping cylinder 41 to rotate. The rotating ring 43 abuts against the mating disc 12, causing the rotating ring 43 to rotate, thereby causing the clamping cylinder 41 to rotate around its own axis, and thus causing the blood collection tube 60 to rotate around its own axis as well. This is a novel plasma mixing method that allows for adjustable, stepless mixing intensity to adapt to different situations.
[0080] Specifically, the rotating ring 43 is driven by the drive assembly 44 to move axially outside the clamping cylinder 41, thereby moving the rotating ring 43 closer to or further away from the rotating shaft 20. When the rotating ring 43 moves away from the rotating shaft 20, the rotation speed of the clamping cylinder 41 caused by the rotating ring 43 increases, thereby increasing the mixing intensity of the plasma in the blood collection tube 60 on the clamping assembly 42 and improving the mixing efficiency. Medical personnel can adjust the position of the rotating ring 43 on the clamping cylinder 41 using the drive assembly 44 to change the mixing efficiency as needed.
[0081] Furthermore, by driving the blood collection tube 60 on the clamping assembly 42 through the driving component 44, the blood collection tube 60 is rotated within the clamping cylinder 41 by an angle, such as 5 degrees or 10 degrees, and then kept stationary. This causes the outer contour of the blood collection tube 60 to resemble the outer contour of an hourglass when rotating around the axis of the clamping cylinder 41. When the blood collection tube 60 is roughly vertical, the plasma, under the action of centrifugal force, can move upward along the tube wall of the blood collection tube 60 before falling, thereby increasing the plasma mixing efficiency. In addition, when the clamping cylinder 41 is roughly horizontal, the plasma moves back and forth between the two ends of the blood collection tube 60 when rotating around the axis of the clamping cylinder 41, further improving the plasma mixing efficiency.
[0082] In one embodiment, the side wall of the clamping cylinder 41 has two or more strip-shaped limiting grooves 411 extending axially therein, and all the strip-shaped limiting grooves 411 are evenly distributed circumferentially with the axis of the clamping cylinder 41 as the center. The inner wall of the rotating ring 43 is connected to the corresponding strip-shaped limiting groove 411. The end of the limiting block 431 away from the rotating ring 43 is inserted into the corresponding strip-shaped limiting groove 411. The limiting block 431 and the strip-shaped limiting groove 411 slide in cooperation along the axial direction of the clamping cylinder 41. One of the limiting blocks 431 has a second hole 432 along the axial direction of the clamping cylinder 41.
[0083] The drive assembly 44 includes a mounting base 441 and a drive shaft 442.
[0084] The fixed base 441 is located inside the clamping cylinder 41 and is connected to the bottom of the closed end of the clamping cylinder 41. One end of the drive shaft 442 is rotatably connected to the fixed base 441, and the other end of the drive shaft 442 passes through the second hole 432 and is located outside the open end of the clamping cylinder 41. The drive shaft 442 is threadedly connected to the second hole 432. A butterfly handle is connected to the end of the drive shaft 442 away from the fixed base 441. The rotation of the drive shaft 442 causes the limiting block 431 to slide within the strip-shaped limiting groove 411, thereby adjusting the position of the rotating ring 43 on the clamping cylinder 41.
[0085] In this embodiment, when the drive shaft 442 is rotated, the limiting block 431 slides along the strip-shaped limiting groove 411, thereby driving the rotating ring 43 to move axially on the clamping cylinder 41. The threaded connection has a self-locking function; when the drive shaft 4424 is stopped, the rotating ring 43 can stably remain in the set position, ensuring that the mixing intensity does not change during operation, thus improving the consistency and repeatability of mixing. The butterfly handle design facilitates manual operation by medical personnel, requiring no additional tools and making operation simple and quick.
[0086] In one embodiment, the clamping assembly 42 includes: two mounting plates 421, a support cylinder 422, a first connecting rod 424, and a second connecting rod 425.
[0087] Two mounting plates 421 are arranged opposite each other, and the two mounting plates 421 and the fixing seat 441 are all located on the diameter of the clamping cylinder 41. The lower end of the support cylinder 422 is closed, and the upper end of the support cylinder 422 is open. The inner wall of the open end of the support cylinder 422 is provided with an annular elastic ring 423 for fixing the blood collection tube 60. The blood collection tube 60 can pass through the annular elastic ring 423 and be inserted into the support cylinder 422. The annular elastic ring 423 can clamp the blood collection tube 60. The support cylinder 422 can be coaxial with the clamping cylinder 41 and is located between the two mounting plates 421. One end of the first connecting rod 424 is connected to the outer wall of the support cylinder 422, and the other end of the first connecting rod 424 is rotatably connected to one of the mounting plates 421. The second connecting rod 425 is coaxial with the first connecting rod 424. One end of the second connecting rod 425 is connected to the outer wall of the support cylinder 422, and the other end of the second connecting rod 425 is rotatably connected to the other mounting plate 421. Specifically, both the first connecting rod 424 and the second connecting rod 425 have coaxial and through mounting holes 21. A mounting post is provided on the mounting plate 421 corresponding to the mounting hole 21, and the mounting post is clearance-fitted with the corresponding mounting hole 21, thereby enabling the first connecting rod 424 and the second connecting rod 425 to be rotatably connected to the mounting plate 421. The two mounting plates 421 and the fixing base 441 are aligned in a straight line. This arrangement allows room for the rotating blood collection tube 60, increasing the range of angles the blood collection tube 60 can rotate within the clamping cylinder 41.
[0088] In one embodiment, the first connecting rod 424 has a first annular groove 426 and a second annular groove 427 arranged in parallel.
[0089] The drive assembly 44 also includes a torsion spring 443, a guide block 444, an external block 445, a slider 447, a third connecting rod 448, a first pulley 449, a second pulley 450, a third pulley 451, and a connecting rope 452. The torsion spring 443 is sleeved on the second connecting rod 425, and its two ends are connected to the mounting cylinder and the mounting plate 421, respectively. The guide block 444 is connected to the side of the mounting plate 421 near the first connecting rod 424, and the side of the guide block 444 facing away from the corresponding mounting plate 421 is an inclined guide surface.
[0090] One end of the outer block 445 is connected to the limiting block 431, and the other end of the outer block 445 extends laterally. The outer block 445 is located behind the mounting plate 421, and a third hole 446 is provided on the outer block 445. One end of the slider 447 is slidably engaged with the third hole 446, and the sliding direction of the slider 447 is perpendicular to the axis of the clamping cylinder 41. One end of the third connecting rod 448 is connected to the slider 447, and the other end of the third connecting rod 448 abuts against the guide surface of the guide block 444. As the third connecting rod 448 gradually moves away from the bottom of the clamping cylinder 41 along the guide surface, it also gradually moves away from the corresponding mounting plate 421.
[0091] The first pulley 449 is rotatably connected to the end of the third connecting rod 448 away from the slider 447. The second pulley 450 is rotatably connected to the corresponding mounting plate 421, and the second pulley 450 is located below the first connecting rod 424. The third pulley 451 is rotatably connected to the corresponding mounting plate 421, and the third pulley 451 is located above the first connecting rod 424.
[0092] One end of the connecting rope 452 is wound and connected to the first annular groove 426. The other end of the connecting rope 452, starting from the side of the first annular groove 426 away from the first pulley 449, passes through the third pulley 451, then around the third pulley 451, then around the side of the first pulley 449 away from the third pulley 451, to the bottom of the second pulley 450, and then around the second pulley 450 before being wound and connected to the side of the second annular groove 427 towards the first pulley 449. Both ends of the connecting rope 452 are fixedly connected to the bottom of the first annular groove 426 and the second annular groove 427.
[0093] When the drive shaft 442 rotates, it causes the limiting block 431 to move axially away from the bottom of the clamping cylinder 41 within the clamping cylinder 41. The limiting block 431 then moves the outer block 445 along with the slider 447. The slider 447 moves along the guide surface of the guide block 444, moving away from the corresponding mounting plate 421. This causes the slider 447 to move the first pulley 449 away from the second pulley 450, the third pulley 451, and the first connecting rod 424. The first pulley 449 pulls the connecting rope 452. The pull of the connecting ropes 452 on both sides of the first pulley 449 causes the wound connecting rope 452 in the first annular groove 426 and the second annular groove 427 on the first connecting rod 424 to be released. Simultaneously, the first connecting rod 424 is driven to rotate, thereby causing the mounting cylinder to rotate, thus rotating the blood collection tube 60 inside the mounting cylinder.
[0094] The drive shaft 442 is threaded into the second hole 432. When the drive shaft 442 is not rotating, the threads on the drive shaft 442 and the threads in the second hole 432 self-lock, allowing the blood collection tube 60 to remain stationary at a certain angle, while the rotating ring 43 remains stationary outside the clamping cylinder 41. Through this ingenious design, the linear motion of the drive shaft 442 is converted into the rotational motion of the support cylinder 422, enabling the blood collection tube 60 to rotate. This allows the plasma to move back and forth between the two ends within the blood collection tube 60, resulting in more thorough mixing. The torsion spring 443 ensures that the connecting rope 452 remains taut at all times, preventing slack or detachment and improving the reliability and service life of the mechanism.
[0095] In one embodiment, a plurality of mounting holes 21 extending axially are provided on the end face of the rotating shaft 20 away from the motor 30, and a plurality of strip-shaped notches 22 corresponding to the mounting holes 21 are also provided on the end face of the rotating shaft 20 away from the motor 30. The strip-shaped notches 22 extend axially along the rotating shaft 20, and the inner side of the strip-shaped notches 22 communicates with the mounting holes 21; the diameter of the mounting holes 21 is greater than the width of the strip-shaped notches 22.
[0096] The clamping mechanism 40 also includes: a connecting seat 46, a connecting block 47, a positioning post 48, a fixing cover 49, and multiple elastic telescopic rods 50.
[0097] The connecting seat 46 is rotatably connected to the closed end of the clamping cylinder 41, and the connecting seat 46 is located between the clamping cylinder 41 and the rotating shaft 20. The connecting block 47 is connected to the end of the connecting seat 46 opposite to the clamping cylinder 41, and the end of the connecting block 47 opposite to the connecting seat 46 can pass through the strip-shaped notch 22. The positioning pin 48 is axially slidably fitted with the mounting hole 21, and the positioning pin 48 is connected to the end of the connecting block 47 opposite to the connecting seat 46. The fixed cover 49 is detachably connected to the end of the rotating shaft 20 using existing technology, and will not be described in detail here.
[0098] Multiple elastic telescopic rods 50 are connected to the fixed cover 49. Each elastic telescopic rod 50 corresponds to a mounting hole 21 and can be inserted into the mounting hole 21 to abut against the corresponding positioning post 48. Specifically, each elastic telescopic rod 50 may include a first sleeve 51, a second sleeve 52, and a spring 53. The first sleeve 51 is connected to the fixed cover 49. One end of the second sleeve 52 is slidably inserted into the end of the first sleeve 51 away from the fixed cover 49, while the other end of the second sleeve 52 is closed. The spring 53 is located inside both the first and second sleeves 51, with one end connected to the closed end of the second sleeve 52 and the other end connected to the fixed cover 49. A retaining ring is fitted over the inner end of the second sleeve 52 located inside the first sleeve. A limiting ring is connected to the inner wall of the first sleeve 51 away from the fixed cover 49. The retaining ring abuts against the limiting ring to ensure that the second sleeve 52 does not separate from the first sleeve 51.
[0099] The clamping cylinder 41 can be removed from the rotating shaft 20. In use, after installing the blood collection tube 60 inside the clamping cylinder 41, insert the positioning pin 48 at the bottom of the clamping cylinder 41 into the rotating shaft 20 from one end of the mounting hole 21. Then, insert the end of the elastic telescopic rod 50 on the fixing cover 49 into the corresponding mounting hole 21, abutting against the positioning pin 48. Connect the fixing cover 49 to the end of the rotating shaft 20. The elastic telescopic rod 50 holds the positioning pin 48 against the bottom of the mounting hole 21. At this time, the rotating ring 43 on the outer periphery of the clamping cylinder 41 abuts against the mating plate 12. Depending on the actual size of the blood collection tube 60 or other tubular containers, the clamping cylinder 41 on the connecting seat 46 and the dimensions of its internal components can be selected in various specifications to improve adaptability. The elastic telescopic rod 50 ensures that even after the size of the clamping cylinder 41 changes, the rotating ring 43 on the clamping cylinder 41 can still abut against the mating plate 12, enabling subsequent actions.
[0100] Numerous specific details are set forth in this specification. However, it will be understood that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures, and techniques have not been shown in detail so as not to obscure the understanding of this specification.
[0101] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be covered within the scope of the claims and specification of the present invention.
Claims
1. A plasma mixing device, characterized in that, include: Rack (10); A rotating shaft (20) is rotatably mounted on a frame (10); A motor (30) is mounted on the frame (10), and the output end of the motor (30) is connected to the end of the rotating shaft (20); and Multiple clamping mechanisms (40) are distributed around the outer periphery of the rotating shaft (20) and connected to the rotating shaft (20). The clamping mechanisms (40) are used to clamp blood collection tubes (60) loaded with blood plasma. The axis of the blood collection tube (60) held in the clamping mechanism (40) is located in the radial direction of the rotating shaft (20). The clamping mechanism (40) can rotate by means of the rotation of the rotating shaft (20). The rotation center line of the clamping mechanism (40) is the axis of the blood collection tube (60).
2. The plasma mixing device as described in claim 1, characterized in that, The frame (10) includes a mounting base (11) and a mating plate (12); the mating plate (12) is fixedly connected to the mounting base (11); a coaxial first hole (121) is opened on the mating plate (12); the rotating shaft (20) is clearance-fitted with the first hole (121); the motor (30) is mounted on the mounting base (11); The clamping mechanism (40) includes: A clamping cylinder (41) has one open end and the other closed end and is rotatably connected to the outer wall of the rotating shaft (20). The axis of the clamping cylinder (41) extends radially along the rotating shaft (20). A clamping assembly (42) is disposed inside a clamping cylinder (41). The clamping assembly (42) is used to clamp a blood collection tube (60) containing plasma and to make the axis of the blood collection tube (60) collinear with the axis of the clamping cylinder (41). A rotating ring (43) is slidably sleeved outside the clamping cylinder (41) along the axial direction of the clamping cylinder (41), and the outer ring of the rotating ring (43) abuts against the end face of the mating disc (12); and The drive assembly (44) is used to drive the rotating ring (43) to slide along the axial direction of the clamping cylinder (41) and then keep it stationary. The drive assembly (44) is also used to drive the blood collection tube (60) on the clamping assembly (42) to rotate and then keep it stationary.
3. The plasma mixing device as described in claim 2, characterized in that, The clamping cylinder (41) has two or more strip-shaped limiting grooves (411) extending along its axial direction on its side wall; all the strip-shaped limiting grooves (411) are evenly distributed circumferentially with the axis of the clamping cylinder (41) as the center; the inner wall of the rotating ring (43) is connected to a limiting block (431) corresponding to the strip-shaped limiting groove (411); the end of the limiting block (431) away from the rotating ring (43) is inserted into the corresponding strip-shaped limiting groove (411); the limiting block (431) and the strip-shaped limiting groove (411) slide in cooperation along the axial direction of the clamping cylinder (41); one of the limiting blocks (431) has a second hole (432) along the axial direction of the clamping cylinder (41). The driver component (44) includes: A fixing seat (441) is located inside the clamping cylinder (41), and the fixing seat (441) is connected to the bottom of the closed end of the clamping cylinder (41); and A drive shaft (442) is provided, one end of which is rotatably connected to the fixed base (441), and the other end of which passes through the second hole (432) and is located outside the open end of the clamping cylinder (41). The drive shaft (442) is threadedly connected to the second hole (432).
4. The plasma mixing device as described in claim 3, characterized in that, The clamping assembly (42) includes: Two mounting plates (421) are arranged opposite to each other, and the two mounting plates (421) and the fixing seat (441) are on the same diameter of the clamping cylinder (41); The support cylinder (422) is closed at the lower end and open at the upper end. The inner wall of the open end of the support cylinder (422) is provided with an annular elastic ring (423) for fixing the blood collection tube (60). The support cylinder (422) can be coaxial with the clamping cylinder (41). The support cylinder (422) is located between two mounting plates (421). A first connecting rod (424) has one end connected to the outer wall of the support cylinder (422) and the other end rotatably connected to one of its mounting plates (421); and The second connecting rod (425) is coaxial with the first connecting rod (424). One end of the second connecting rod (425) is connected to the outer wall of the support cylinder (422), and the other end of the second connecting rod (425) is rotatably connected to another mounting plate (421).
5. The plasma mixing device as described in claim 4, characterized in that, The first connecting rod (424) has a first annular groove (426) and a second annular groove (427) arranged in parallel. The driving component (44) also includes: Torsion spring (443), the torsion spring (443) is sleeved on the outside of the second connecting rod (425), and the two ends of the torsion spring (443) are respectively connected to the mounting cylinder and the mounting plate (421); Guide block (444), the guide block (444) is connected to the side of the mounting plate (421) near the first connecting rod (424), and the side of the guide block (444) facing away from the corresponding mounting plate (421) is an inclined guide surface; An external block (445) is provided, one end of which is connected to the limiting block (431), the other end of which extends laterally, and the external block (445) is located behind the mounting plate (421). A third hole (446) is provided on the external block (445). A slider (447) is provided, one end of which is slidably engaged with a third hole (446), and the sliding direction of the slider (447) is perpendicular to the axis of the clamping cylinder (41). The third connecting rod (448) has one end connected to the slider (447) and the other end abutting against the guide surface of the guide block (444). As the third connecting rod (448) moves away from the bottom of the clamping cylinder (41) along the guide surface, it also moves away from the corresponding mounting plate (421). The first pulley (449) is rotatably connected to the end of the third connecting rod (448) away from the slider (447); The second pulley (450) is rotatably connected to the corresponding mounting plate (421), and the second pulley (450) is located below the first connecting rod (424); A third pulley (451) is rotatably connected to the corresponding mounting plate (421), and the third pulley (451) is located above the first connecting rod (424); and A connecting rope (452) is wound and connected at one end to the first annular groove (426). The other end of the connecting rope (452) passes from the side of the first annular groove (426) away from the first pulley (449), passes through the side of the third pulley (451) away from the first pulley (449), goes around the third pulley (451), goes around the side of the first pulley (449) away from the third pulley (451), goes under the second pulley (450), passes around the second pulley (450), and then is wound and connected to the second annular groove (427) from the side of the second annular groove (427) towards the first pulley (449).
6. The plasma mixing device as described in claim 5, characterized in that, The end face of the rotating shaft (20) away from the motor (30) is provided with a plurality of mounting holes (21) extending along its axial direction. The end face of the rotating shaft (20) away from the motor (30) is also provided with a plurality of strip-shaped notches (22) corresponding to the mounting holes (21). The strip-shaped notches (22) extend along the axial direction of the rotating shaft (20), and the inner side of the strip-shaped notches (22) communicates with the mounting holes (21). The diameter of the mounting holes (21) is greater than the width of the strip-shaped notches (22). The clamping mechanism (40) further includes: Connecting seat (46), the connecting seat (46) is rotatably connected to the closed end of the clamping cylinder (41), and the connecting seat (46) is located between the clamping cylinder (41) and the rotating shaft (20); Connecting block (47), the connecting block (47) is connected to the end of the connecting seat (46) away from the clamping cylinder (41), and the end of the connecting block (47) away from the connecting seat (46) can pass through the strip notch (22). The positioning post (48) is axially slidably fitted with the mounting hole (21), and the positioning post (48) is connected to the end of the connecting block (47) away from the connecting seat (46). The fixed cover (49) is detachably connected to the end of the rotating shaft (20); and Multiple elastic telescopic rods (50) are connected to the fixed cover (49). The elastic telescopic rods (50) correspond to the mounting holes (21). The elastic telescopic rods (50) can be inserted into the mounting holes (21) and abut against the corresponding positioning pins (48).