Cosmetic composition for broad-spectrum UV protection and beautifying light-reversal light damage repair and application of cosmetic composition

Abstract

The invention provides a cosmetic composition for broad-spectrum UV protection and beautifying light-reversal light damage repair and application of the cosmetic composition, and belongs to the technical field of cosmetics. The cosmetic composition comprises a photoactivating enzyme repair factor, a hedychium coronarium root extract and a white water lily flower extract, and the composition also comprises a QUERCARE royalin. The light activating enzyme repair factor, the hedychium coronarium root extract and the white water lily flower extract are compounded, so that light injury recovery is accelerated, the efficiency of a sunscreen product is improved, after-sun adverse reactions are reduced, the sunscreen composition has soothing and whitening effects, the phogenin not only absorbs ultraviolet rays, but also converts the ultraviolet rays into beautifying light, light for skin injury is converted into light beneficial to skin from the source, and the skin care effect is improved. The anti-inflammatory and soothing effects are achieved, collagen degradation is reduced, DNA damage and mutation are inhibited, cell nucleus aging is reduced, and grease secretion is inhibited. The cosmetic composition disclosed by the invention is suitable for a skin care product with high sunscreen requirement and light aging resistance, and has instant protection and long-term repair functions.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of cosmetic technology, in particular to a cosmetic composition for broad-spectrum UV protection and cosmetic photoreversal of photodamage and application thereof. BACKGROUND

[0002] With the aggravation of environmental pollution and ozone layer destruction, the harm of ultraviolet (UV) radiation to human skin is increasingly serious. UVA (320-400 nm) and UVB (280-320 nm) in UV can penetrate different depths of the skin, causing photoaging, pigmentation, inflammation, and even skin cancer. Long-term exposure to UV radiation can lead to collagen degradation, elastin rupture, and free radical accumulation, accelerating skin aging. In addition, visible light and infrared (IRA) can also exacerbate photodamage by inducing oxidative stress. Therefore, it has become a research hotspot to develop cosmetics with broad-spectrum UV protection and photodamage repair functions.

[0003] Currently, sunscreen products on the market mainly rely on chemical sunscreens and physical sunscreens to block or absorb UV rays. However, traditional sunscreen products have limitations: they can cause skin irritation or photosensitivity; physical sunscreens can easily cause whitening, affecting the user experience; they only focus on UVB protection, and lack protection against UVA and visible light; and they lack repair functions for photodamage. In terms of photodamage repair, common active ingredients include antioxidants, plant extracts, and cell repair factors. These ingredients can alleviate photodamage by scavenging free radicals, inhibiting inflammation, or promoting collagen synthesis, but their effectiveness is limited by poor stability, low transdermal absorption rate, or single mechanism of action.

[0004] Therefore, it is of great significance to develop a cosmetic composition with broad-spectrum UV protection, high-efficiency antioxidant, and photodamage reversal functions. SUMMARY

[0005] The present application relates to the field of cosmetic technology, in particular to a cosmetic composition for broad-spectrum UV protection and cosmetic photoreversal of photodamage and application thereof.

[0006] To achieve the above-mentioned application purposes, the present application provides the following technical solutions: The present application provides a cosmetic composition for broad-spectrum UV protection and cosmetic photoreversal of photodamage, comprising a light-activated enzyme repair factor, a ginger flower root extract, and a white water lily flower extract.

[0007] Preferably, the weight ratio of the light-activated enzyme repair factor, the ginger flower root extract, and the white water lily flower extract is (0.3-0.5):(4-6):(2-4).

[0008] Preferably, QUERCARE sunscreen is further included.

[0009] More preferably, the weight ratio of QUERCARE sunscreen, light-activated enzyme repair factor, ginger flower root extract and white water lily flower extract is (0.3-0.5):(0.3-0.5):(4-6):(2-4).

[0010] Preferably, chemical sunscreens, physical sunscreens and photodamage repair agents are further included.

[0011] More preferably, the photodamage repair agent is composed of rockrose leaf extract, red mushroom extract and hydrolyzed red algae extract.

[0012] More preferably, the physical sunscreen is composed of titanium dioxide and silica.

[0013] Preferably, cosmetically acceptable adjuvants are further included.

[0014] The application also provides the use of the above-mentioned cosmetic composition in sunscreen cosmetics.

[0015] The application also provides the use of the above-mentioned cosmetic composition in photodamage repair cosmetics.

[0016] Compared with the prior art, the application has the following beneficial effects: The application provides a cosmetic composition for broad-spectrum UV protection and photodamage repair of cosmetic photoreversal, which comprises: light-activated enzyme repair factor, ginger flower root extract and white water lily flower extract; further comprises QUERCARE sunscreen, physical sunscreen, chemical sunscreen and photodamage repair agent, and the photodamage repair agent is composed of rockrose leaf extract, red mushroom extract and hydrolyzed red algae extract. After the three active ingredients of light-activated enzyme repair factor, ginger flower root extract and white water lily flower extract are scientifically compounded, they have the effects of enhancing the ultraviolet defense system, accelerating photodamage recovery, resisting photoaging, delaying skin aging, improving the performance of sunscreen products, soothing and whitening; through the synergistic effect of physical sunscreen and chemical sunscreen, more ultraviolet bands can be covered, and ultraviolet rays can be effectively blocked and absorbed, providing comprehensive UV protection and preventing skin sunburn, tanning, photoaging and other problems caused by ultraviolet radiation; the photodamage repair agent forms a full-link photodamage repair system of “defense-repair-reversal”, which can comprehensively cope with skin photoaging problems caused by ultraviolet rays (UVA / UVB), blue light, pollution and other environmental factors, and promote skin barrier repair and rejuvenation. The cosmetic composition of the application is suitable for high-sunscreen-demand and anti-photoaging skin care products, and has the functions of immediate protection and long-term repair. DETAILED DESCRIPTION

[0017] The present application provides a cosmetic composition for broad-spectrum UV protection and cosmetic photoreversal light damage repair, characterized in that it comprises a photoactivated enzyme repair factor, a ginger flower root extract and a white water lily flower extract.

[0018] The weight ratio of the photoactivated enzyme repair factor, the ginger flower root extract and the white water lily flower extract is preferably (0.3-0.5):(4-6):(2-4), more preferably 0.4:5:3.

[0019] The photoactivated enzyme repair factor can specifically target cyclobutane pyrimidine dimer repair; it can be activated by light to quickly and completely repair damaged DNA; the enzyme can repeatedly participate in the reaction, and the photolytic enzyme acts as a catalyst to participate in the repair process, and the characteristics do not change, and can be recycled for repair; it can remove active oxygen generated by ultraviolet irradiation; it has a calming effect, enhances immunity and reduces post-sun pain by reducing the expression of pro-inflammatory cytokines; it reduces the content of metalloproteinase to prevent wrinkle formation and resist photoaging; and it can improve the protection ability of sunscreen cream with sunscreen ingredients. The ginger flower root extract can scavenge free radicals, reduce photooxidative damage, inhibit MMP-1 activity to protect collagen, and at the same time reduce the generation of AGEs (glycation end products), thereby delaying skin yellowing; more importantly, it can provide multiple protection for the skin against aging (UVA model) and external pollution (blue light and benzo[a]pyrene model), and significantly improve the abnormal energy metabolism of the skin caused by UVA. The white water lily flower extract can enhance the defense of the skin, calm the skin tissue by reducing inflammation, relieve skin discomfort symptoms caused by sunlight stimulation and chemical stimulation, and at the same time reduce pigmentation caused by inflammatory stress, thereby achieving the effect of whitening the skin.

[0020] The three active ingredients of the photoactivated enzyme repair factor, the ginger flower root extract and the white water lily flower extract are scientifically compounded to enhance the ultraviolet defense system, form a triple protection network of "immediate repair (DNA) + antioxidant (free radicals) + anti-inflammatory (barrier protection)", cover different damage stages (acute damage, oxidative stress, chronic inflammation) caused by ultraviolet rays, and achieve comprehensive repair from the molecular to the tissue level; accelerate the recovery of photodamage and achieve comprehensive repair from the molecular to the tissue level; at the same time, target the three major photoaging pathways of "collagen degradation + glycation + pigmentation", which is more comprehensive than single ingredients; improve the efficacy of sunscreen products and make up for the shortcomings of traditional sunscreen agents; reduce adverse reactions after sun exposure and have the effects of soothing and whitening.

[0021] The application also preferably comprises 0.3-0.5 parts by weight of QUERCARE light-protecting substance. In one aspect, the QUERCARE light-protecting substance has a highly coincident absorption peak with UVA&UVB, can absorb ultraviolet rays, and is converted into cosmetic light, thereby converting the light damaging to the skin into light beneficial to the skin from the source; in another aspect, the QUERCARE light-protecting substance has strong antioxidant and anti-inflammatory soothing effects, protects the integrity and density of the stratum corneum, and protects the thickness and density of the granular layer and the stratum spinosum, reduces the collagen degradation caused by UVB, inhibits DNA damage and mutation caused by ultraviolet rays, and reduces the nuclear senescence caused by ultraviolet rays, and inhibits oil secretion.

[0022] The application also comprises a chemical sunscreen agent, a physical sunscreen agent, and a light damage repair agent.

[0023] The chemical sunscreen agent preferably consists of bis-ethylhexyloxyphenol methoxyphenyl triazine, avobenzone, and octocrylene in a weight ratio of (2-4):(1-3):(3-5), and more preferably 3:2:4. The bis-ethylhexyloxyphenol methoxyphenyl triazine achieves all-around protection by absorbing, scattering, and reflecting ultraviolet rays, and is not absorbed by the skin, can stabilize avobenzone to reduce photodegradation; avobenzone is a wide-spectrum UVA absorber; octocrylene improves the spreadability of the cosmetic composition, and can significantly improve the photostability of avobenzone and other UVA sunscreen agents, and enhance the overall sunscreen efficacy. The combination of the three can achieve full-spectrum coverage, improve the sunscreen effect, and bis-ethylhexyloxyphenol methoxyphenyl triazine and octocrylene can stabilize avobenzone from photodegradation.

[0024] The physical sunscreen agent preferably consists of titanium dioxide and silica, and the weight ratio of the titanium dioxide and silica is preferably 40-45:55-60, and more preferably 42:58. The physical sunscreen agent can improve the SPF value, reduce shine, has super-light texture, enhances the transparent feeling, and has good compatibility with the thickening agent.

[0025] The light damage repair agent consists of rockrose leaf extract, red mushroom extract, and hydrolyzed red algae extract.

[0026] The Cistus canescens leaf extract of the present application is obtained by ethanol-microwave extraction. The Cistus canescens leaf extract of the present application has the effects of photoprotection, anti-pollution and anti-oxidation, promotion of skin repair and renewal, anti-aging and improvement of skin quality. The photoprotection effect can resist blue light damage: reduce collagen degradation caused by electronic device blue light, inhibit the activity of metal matrix proteinase MMP-1, protect the dermal structure, prevent UVA / UVB: scavenge free radicals, reduce oxidative stress, prevent lipid peroxidation; reduce DNA damage, promote DNA repair gene expression, reduce inflammatory factors. Anti-pollution and anti-oxidation: neutralize the oxidative stress induced by air pollutants and UVA, reduce cell membrane damage, and have strong antioxidant activity. Promote skin repair and renewal: shorten the epidermal renewal cycle, help the skin recover quickly, enhance the skin recovery ability, improve the skin barrier function and repair after light damage. Anti-aging and improvement of skin quality: reduce wrinkles and fine lines, make the skin smoother through promoting collagen protection and reducing inflammation.

[0027] The Ganoderma lucidum extract of the present application is obtained by complex enzyme hydrolysis. The Ganoderma lucidum extract of the present application regulates sensory receptors, helps to relieve discomfort; reduces the content of inflammatory markers, reduces local inflammation; can increase the synthesis of filaggrin, improve the moisturizing effect, and improve the skin barrier; has the effects of instant and long-term moisturizing, instant relief of stinging, and instant reduction of redness.

[0028] The hydrolyzed red algae extract of the present application is obtained by aerobic fermentation of Paracaseolyticum CICC 25261 and anaerobic fermentation of Bifidobacterium adolescentis CICC 24573 in sequence. The hydrolyzed red algae extract of the present application realizes the reversal of skin aging from the cellular level through the triple mechanism of reversing cell aging + autophagy activation + light damage repair, and is especially suitable for improving deep wrinkles, laxity and photoaging problems. Reverse cell aging: reduce the release of pro-inflammatory factors, block inflammatory damage to surrounding tissues, degrade key factors of aging, reduce the expression of senescent cell markers, and restore cell youth. Activate autophagy and cell energy: increase the expression of autophagy markers, remove damaged organelles and metabolic waste, and enhance autophagy activity; improve cell energy, improve mitochondrial function, and restore cell metabolic activity. Repair photoaging and oxidative damage: scavenge hydroxyl radicals, inhibit ROS and lipid peroxidation; protect collagen and hyaluronic acid, reduce collagen degradation, promote the synthesis of type I procollagen and hyaluronic acid, and improve the structure of the dermal layer.

[0029] The Cistus canescens leaf extract, Ganoderma lucidum extract and hydrolyzed red algae extract in the light damage repair agent of the present application are compounded to form a "defense-repair-reverse" full-link light damage repair system, which can comprehensively cope with skin photoaging problems caused by environmental factors such as ultraviolet light (UVA / UVB), blue light, pollution, etc., and promote skin barrier repair and rejuvenation.

[0030] The moisturizer, antioxidant, emulsifier, film forming agent and preservative in the present application are all selected from raw materials known in the cosmetic field. As a preferred solution, the moisturizer includes, but is not limited to, at least one of glycerin, sorbitol, betaine and panthenol; the antioxidant includes, but is not limited to, at least one of ascorbic acid, tocopherol and ferulic acid; the emulsifier includes, but is not limited to, at least one of steareth-2, steareth-21 and PEG-40 stearate; the film forming agent includes, but is not limited to, at least one of VP / eicosene copolymer, polyvinylpyrrolidone K30 and polymethylsilsesquioxane; the preservative includes, but is not limited to, at least one of phenoxyethanol, ethylhexylglycerin and 1,2-pentanediol; and the solvent is preferably water.

[0031] The method for using the cosmetic composition of the present application is as follows: after washing the skin and basic skin care, take a 1-yuan coin sized (about 0.9 g) cosmetic composition, and apply it to five places of the cheeks, forehead, nose tip and chin with fingertips, and massage it evenly in the same direction in a clockwise circle, and then it can be used after film formation.

[0032] The present application also provides the use of the above cosmetic composition in sunscreen cosmetics.

[0033] The present application also provides the use of the above cosmetic composition in light damage repair cosmetics.

[0034] The technical solutions in the present application will be described clearly and completely in combination with the embodiments in the present application. Obviously, the described embodiments are only some of the embodiments of the present application, but not all the embodiments. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the present application.

[0035] In the following examples, all the conventional methods are used unless otherwise specified.

[0036] In the following examples, all the materials and reagents used are commercially available unless otherwise specified.

[0037] The photoactivated enzyme repair factor is ALGAKTIV ®GenoFix CPD light-activated enzyme repair factor, disclosed in international patent No. WO2017013183A1, INCI name is SPIRULINA MAXIMA extract / lecithin / 1,3-propanediol / water, purchased from Guangzhou Bochi Biotechnology Co., Ltd.; polyvinylpyrrolidone K30 purchased from Anhui Weimao Biological Technology Co., Ltd., item number 6686686645; steareth-2 purchased from Guangzhou Chenuo Biological Technology Co., Ltd., item number ET85237; steareth-21 purchased from Yichang Mingya New Material Technology Co., Ltd., item number MY972-B; polysiloxane quaternary ammonium salt-12 purchased from Guangdong Wengjiang Chemical Reagent Co., Ltd., item number PB90591; VP / eicosene copolymer purchased from Guangzhou Baolong International Trade Co., Ltd., item number V-220F; cellulase purchased from Qingdao Weisen Biological Technology Co., Ltd., enzyme activity 100,000 U / g, item number X5641; pectinase purchased from Ningxia Xiasen Industrial Group Co., Ltd., enzyme activity 60,000 U / g, item number FDY-2212; QUERCARE light care essence is QUERCARE™ light care essence, purchased from Shanghai Huiwen Biotechnology Co., Ltd.; ginger root extract is from Guangzhou Baihaobo Co., Ltd.; white water lily flower extract is from Sederma, France; chamomile extract, calendula extract and licorice extract are all purchased from Shanxi Baowo Biological Technology Co., Ltd., item numbers are sxbb389869893, SXBBGGYTQY and sxbb789489384112 respectively.

[0038] Example 1 Cosmetic composition for repairing photodamage with broad-spectrum UV protection and cosmetic photoreversal Accurately weigh 0.4 parts of light-activated enzyme repair factor, 5 parts of ginger root extract, 3 parts of white water lily flower extract and 0.4 parts of QUERCARE light care essence by weight; mix the above components to obtain a cosmetic composition.

[0039] Example 2 Cosmetic composition for repairing photodamage with broad-spectrum UV protection and cosmetic photoreversal Accurately weigh 0.3 parts of light-activated enzyme repair factor, 6 parts of ginger root extract, 2 parts of white water lily flower extract and 0.5 parts of QUERCARE light care essence by weight; mix the above components to obtain a cosmetic composition.

[0040] Example 3 Cosmetic composition for repairing photodamage with broad-spectrum UV protection and cosmetic photoreversal Accurately weigh 0.5 parts of light-activated enzyme repair factor, 4 parts of ginger root extract, 4 parts of white water lily flower extract and 0.3 parts of QUERCARE light care essence by weight; mix the above components to obtain a cosmetic composition.

[0041] Test Example 1 Animal Experiment Healthy SKH-1 hairless mice, 8 weeks old, weighing 20-25 g, half male and half female, were selected. The mice were raised in a standard environment, with temperature controlled at 22-25℃, humidity maintained at 50%-60%, light cycle of 12 h light and 12 h dark, and free access to food and water. After the mice were adapted to the environment for 1 week, the experiment was started to reduce the interference of environmental changes on the experimental results.

[0042] Preparation of the emulsion of the example: 5 parts of the example composition, 65 parts of deionized water, 20 parts of liquid paraffin, 8 parts of Tween-80 and 2 parts of glycerol were accurately weighed by weight parts; the example composition, deionized water and glycerol were mixed to obtain an aqueous phase; liquid paraffin and Tween-80 were mixed to obtain an oil phase; the oil phase was poured into the aqueous phase, stirred at 600 rpm for 10 min to obtain the emulsion of the example.

[0043] The mice were randomly divided into 6 groups, 10 mice in each group, and the specific grouping was as follows: Blank control group: no ultraviolet irradiation treatment, no application of any cosmetics, only normal feeding in the same feeding environment.

[0044] Model control group: only ultraviolet irradiation, no application of cosmetics.

[0045] Positive control group: 30 min before ultraviolet irradiation, 0.2 g of Shiseido Anhesha was applied on the back of the mouse, and then ultraviolet irradiation was performed.

[0046] Example 1 group: 30 min before ultraviolet irradiation, 0.2 g of the emulsion of the composition of Example 1 was applied on the back of the mouse, and then ultraviolet irradiation was performed.

[0047] Example 2 group: 30 min before ultraviolet irradiation, 0.2 g of the emulsion of the composition of Example 2 was applied on the back of the mouse, and then ultraviolet irradiation was performed.

[0048] Example 3 group: 30 min before ultraviolet irradiation, 0.2 g of the emulsion of the composition of Example 3 was applied on the back of the mouse, and then ultraviolet irradiation was performed.

[0049] An ultraviolet lamp was used as the light source, mainly emitting medium wave ultraviolet rays (UVB) with a wavelength range of 280-320 nm. By adjusting the distance between the mouse and the ultraviolet lamp, the irradiation intensity was controlled within a certain range, which was determined to be 0.5 mW / cm 2 . Irradiation was performed 3 times a week, each time for 30 min, for 4 consecutive weeks.

[0050] (1) Subjective score and skin erythema index The skin of each group of mice was scored for erythema, scaling, wrinkles, etc. The scoring criteria are as follows: Erythema: no erythema is 0 points, mild erythema is 1 point, moderate erythema is 2 points, and severe erythema is 3 points. Scaling: no scaling is 0 points, mild scaling is 1 point, moderate scaling is 2 points, and severe scaling is 3 points. Wrinkles: no wrinkles are 0 points, mild wrinkles are 1 point, moderate wrinkles are 2 points, and severe wrinkles are 3 points. Scoring: scoring was performed after the end of the experiment (24 hours after the last UV irradiation) by 5 professionals independently, and the average value was taken.

[0051] After scoring, the skin erythema index of the back of the mice was measured using a skin tester using the skin spectrum measurement method.

[0052] The subjective score and skin erythema index results are shown in Table 1.

[0053] Table 1. Subjective score and skin erythema index results of each group Group Erythema (points) Desquamation (points) Wrinkle (points) Total score Erythema index Blank control group 0 0 0 0 16.5 Model group 2.3 2.1 1.7 6.1 42.3 Positive control group 0.6 0.5 0.4 1.5 19.7 Example 1 group 0.5 0.4 0.3 1.2 17.3 Example 2 group 0.5 0.5 0.5 1.5 17.8 Example 3 group 0.6 0.4 0.4 1.4 18.2 As can be seen from the results in Table 1, compared with the blank control group, the skin of the model group showed obvious erythema, scaling, and photoaging wrinkles, and the erythema index was significantly increased, indicating that the mouse model was successfully constructed; the skin damage of the positive control group was slight; the erythema, scaling, and wrinkles of the Example 1-3 groups were significantly improved compared with the model group, and the erythema index was significantly reduced, and the Example 1 group had the best effect and was higher than the subjective score of the positive control group, which may be due to the fact that the examples contain not only sunscreen ingredients but also soothing and repairing ingredients, which can accelerate the recovery of photo-damage and reduce post-sun adverse reactions.

[0054] (2) Oxidative stress indicators After the skin erythema index was determined, the mice were sacrificed by cervical dislocation, the complete skin tissue of the irradiated area was cut, the excess fat and other connective tissue was removed, and the SOD, GSH-Px activity and MDA content in the skin tissue were determined according to the method provided in the kit. The specific results are shown in Table 2.

[0055] Table 2. Oxidative stress indicators of mice in each group Group SOD activity (U / mg prot) GSH-Px activity (U / mg prot) MDA (nmol / mg prot) Blank control group 118.71 55.82 4.31 Model group 62.38 33.06 8.85 Positive control group 98.60 50.41 4.92 Example 1 group 103.04 52.19 4.56 Example 2 group 100.25 50.75 4.84 Example 3 group 99.29 51.03 4.72 As can be seen from the data in Table 2, the SOD and GSH-Px activity of the model group was significantly reduced, and the MDA content was significantly increased, which was significantly different from the blank control group, indicating that the mouse model was successfully constructed. The Example 1-3 groups showed better effects than the positive control group in improving SOD and GSH-Px activity and reducing MDA content, indicating that the composition of the examples can play a repairing role by enhancing the activity of endogenous antioxidant enzymes and inhibiting lipid peroxidation.

[0056] Example 4 (1) Preparation of light damage repair agent Preparation of Cistus canescens leaf extract: Cistus canescens leaves were dried and crushed to pass through a 200-mesh sieve, and then 60% ethanol by volume was added at a solid-liquid ratio of 1:20 g / mL. Microwave extraction was performed at 400 W, 60°C, and pH 5.5 for 20 min. After filtration, concentration, and drying to a water content of 4 wt%, Cistus canescens leaf extract was obtained. Preparation of Ganoderma lucidum extract: Ganoderma lucidum fruiting bodies were ground to obtain ground material 1. The ground material 1 was mixed with water at a solid-liquid ratio of 1:10 g / mL, and 2% of a composite enzyme by weight of the ground material 1 was added. Enzymatic hydrolysis was performed at 55°C and pH 4.8 for 30 min. After filtration, the filtrate was concentrated and dried to a water content of 2 wt% to obtain Ganoderma lucidum extract. The composite enzyme was composed of cellulase and pectinase at a weight ratio of 3:1. Preparation of hydrolyzed red algae extract: Warm spring red algae were ground to obtain ground material 2. Water was added at a solid-liquid ratio of 1:30 g / mL, and sterilization was performed. Bacterium Bifidobacterium adolescentis CICC 24573 was inoculated at a bacterial activity of 5×10 9 cfu / mL. After aerobic fermentation at 37°C, pH 6.8, and a rotation speed of 200 rpm for 36 h, bacterium Paracaseolus casei CICC 25261 was inoculated at a bacterial activity of 5×10 9 cfu / mL. After anaerobic fermentation at 37°C and pH 7 for 60 h, sterilization was performed. Filtration was performed, and the filtrate was concentrated and dried to a water content of 4 wt% to obtain the hydrolyzed red algae extract. The inoculation amount of Paracaseolus casei CICC 25261 was 1.5% by weight of the ground material 2, and the inoculation amount of Bifidobacterium adolescentis CICC 24573 was 2% by weight of the ground material 2. The Cistus canescens leaf extract, Ganoderma lucidum extract, and hydrolyzed red algae extract were mixed at a weight ratio of 0.005:0.1:2 to obtain the light damage repair agent. (2) Preparation of cosmetic composition for broad-spectrum UV protection and beauty light reverse light damage repair Titanium dioxide and silicon stone were mixed at a weight ratio of 42:58 to obtain a physical sunscreen agent. Bis-ethylhexyloxyphenol methoxyphenyl triazine, avobenzone, and octocrylene were mixed at a weight ratio of 3:2:4 to obtain a chemical sunscreen agent. The following ingredients were accurately weighed in 100 parts by weight: 8 parts of the physical sunscreen agent, 12 parts of the chemical sunscreen agent, 0.4 parts of the photoactivated enzyme repair factor, 5 parts of the ginger flower root extract, 3 parts of the white calla flower extract, 0.4 parts of QUERCARE light protection essence, 2.105 parts of the light damage repair agent, 3 parts of glycerol, 2 parts of panthenol, 1 part of ascorbic acid, 0.5 parts of ferulic acid, 1 part of steareth-2, 1 part of steareth-21, 3 parts of polyvinylpyrrolidone K30, 0.2 parts of phenoxyethanol, and the balance of water. The physical sunscreen agent was mixed with 16 parts by weight of water, ultrasonically treated at 150 W for 25 min to obtain a physical sunscreen agent dispersion; the chemical sunscreen agent, ascorbic acid, ferulic acid, steareth-2 and steareth-21 were mixed, heated at 70°C for 10 min to obtain an oil phase; the remaining water, glycerin, panthenol, polyvinylpyrrolidone K30 and phenoxyethanol were mixed to obtain an aqueous phase; the oil phase was added to the aqueous phase, homogenized at 8000 rpm for 5 min, then the physical sunscreen agent dispersion was added, homogenized at 5000 rpm for 2 min, the photoactivated enzyme repair factor, ginger lily root extract, white water lily flower extract, QUERCARE light-resistant substance and photo-damage repair agent were added, stirred at 200 rpm for 20 min, the pH value was adjusted to 6.3, vacuum degassed, sterilized to obtain the cosmetic composition.

[0057] Example 5 (1) Preparation of photo-damage repair agent Preparation of Cistus canescens leaf extract: Cistus canescens leaves were dried, crushed and passed through a 150-mesh sieve, 58% ethanol by volume was added according to a solid-liquid ratio of 1:18 g / mL, and microwave extraction was performed at 350 W, 58°C, pH 5.2 for 25 min. After filtration, concentration and drying to a water content of 3 wt%, Cistus canescens leaf extract was obtained; Preparation of Ganoderma lucidum extract: Ganoderma lucidum fruiting bodies were ground to obtain grinding material 1, which was mixed with water according to a solid-liquid ratio of 1:10 g / mL, and 2% of the weight of the grinding material 1 was added to the compound enzyme. Enzymatic hydrolysis was performed at 55°C and pH 4.5 for 35 min. After filtration, the filtrate was concentrated and dried to a water content of 3 wt% to obtain Ganoderma lucidum extract. The compound enzyme was composed of cellulase and pectinase in a weight ratio of 2:0.5; Preparation of hydrolyzed red algae extract: hot spring red algae were ground to obtain grinding material 2, which was mixed with water according to a solid-liquid ratio of 1:25 g / mL, sterilized, inoculated with Paracaseicola casei CICC 25261 with a bacterial activity of 2×10 9 cfu / mL, and subjected to aerobic fermentation at a temperature of 35°C, a pH value of 6.5 and a rotation speed of 150 rpm for 48 h. Then, Bifidobacterium adolescentis CICC 24573 with a bacterial activity of 4×10 9 cfu / mL was inoculated, subjected to anaerobic fermentation at a temperature of 35°C and a pH value of 6.7 for 72 h, sterilized, filtered, concentrated and dried to a water content of 2 wt% to obtain the hydrolyzed red algae extract. The inoculation amount of Paracaseicola casei CICC 25261 was 1% of the weight of the grinding material 2, and the inoculation amount of Bifidobacterium adolescentis CICC 24573 was 1.5% of the weight of the grinding material 2; The Cistus canescens leaf extract, Ganoderma lucidum extract and hydrolyzed red algae extract were mixed according to a weight ratio of 0.01:0.12:1 to obtain the photo-damage repair agent; (2) Preparation of cosmetic composition for repairing photodamage by broad-spectrum UV protection and cosmetic photoreversal Titanium dioxide and silica were mixed in a weight ratio of 40:60 to obtain a physical sunscreen agent; Bis-ethylhexyloxyphenol methoxyphenyl triazine, avobenzone and octocrylene were mixed in a weight ratio of 2:1:3 to obtain a chemical sunscreen agent; Accurately weigh 5 parts of the physical sunscreen agent, 15 parts of the chemical sunscreen agent, 0.3 parts of the light-activated enzyme repair factor, 6 parts of the ginger flower root extract, 2 parts of the white water lily flower extract, 0.5 parts of QUERCARE light-protecting substance, 1.13 parts of the photodamage repair agent, 5 parts of glycerol, 2 parts of sorbitol, 0.5 parts of ascorbic acid, 0.5 parts of tocopherol, 3 parts of PEG-40 stearate, 2 parts of VP / eicosene copolymer, 0.3 parts of ethylhexylglycerin, and the balance of water, based on 100 parts by weight; The physical sunscreen agent was mixed with 15 parts by weight of water and ultrasonically treated at 120 W for 30 min to obtain a physical sunscreen agent dispersion; the chemical sunscreen agent, ascorbic acid, tocopherol, PEG-40 stearate, and VP / eicosene copolymer were mixed and heated at 65°C for 15 min to obtain an oil phase; the remaining water, glycerol, sorbitol, and ethylhexylglycerin were mixed to obtain an aqueous phase; the oil phase was added to the aqueous phase, homogenized at 7500 rpm for 6 min, then the physical sunscreen agent dispersion was added and homogenized at 4000 rpm for 3 min, the light-activated enzyme repair factor, ginger flower root extract, white water lily flower extract, QUERCARE light-protecting substance, and photodamage repair agent were added, stirred at 180 rpm for 30 min, the pH value was adjusted to 6, vacuum degassing was performed, sterilization was performed, and a cosmetic composition was obtained.

[0058] Example 6 (1) Preparation of photodamage repair agent Preparation of Cistus canescens leaf extract: Cistus canescens leaves were dried, crushed, and passed through a 250-mesh sieve, and then 65% ethanol by volume was added at a solid-liquid ratio of 1:23 g / mL, and microwave extraction was performed at 450 W, 65°C, and pH 5.8 for 18 min; filtration, concentration, and drying were performed until the water content was 3 wt%, and a Cistus canescens leaf extract was obtained; Preparation of Ganoderma lucidum extract: Ganoderma lucidum fruiting bodies were ground to obtain ground material 1, which was mixed with water at a solid-liquid ratio of 1:12 g / mL, and a complex enzyme was added at 3% by weight of the ground material 1; enzyme hydrolysis was performed at 58°C and pH 5 for 25 min; the filtrate was concentrated and dried until the water content was 3 wt% to obtain a Ganoderma lucidum extract; the complex enzyme was composed of cellulase and pectinase at a weight ratio of 4:3; Preparation of hydrolyzed red algae extract: hot spring red algae were ground to obtain ground material 2, which was mixed with water at a solid-liquid ratio of 1:32 g / mL, sterilized, inoculated with bacteria with an activity of 4×10 9Bifidobacterium adolescentis CICC 24573 at 1.5 x 10 9 Bifidobacterium adolescentis CICC 24573 at 1.5 x 10 The rockrose leaf extract, the red mushroom extract and the hydrolyzed red algae extract are mixed according to the weight ratio of 0.003:0.08:3 to obtain the light damage repair agent. (2) Preparation of a cosmetic composition for repairing light damage by broad-spectrum UV protection and beauty light reversal Titanium dioxide and silica are mixed according to the weight ratio of 45:55 to obtain the physical sunscreen agent. Bis-ethylhexyloxyphenol methoxyphenyl triazine, avobenzone and octocrylene are mixed according to the weight ratio of 4:3:5 to obtain the chemical sunscreen agent. The physical sunscreen agent 10 parts, the chemical sunscreen agent 10 parts, the light-activated enzyme repair factor 0.5 part, the ginger flower root extract 4 parts, the white water lily flower extract 4 parts, the QUERCARE light protection essence 0.3 part, the light damage repair agent 3.083 parts, the glycerol 3 parts, the betaine 1 part, the tocopherol 2 parts, the ferulic acid 0.5 part, the steareth-2 0.5 part, the steareth-2 10.5 part, the dimethicone 4 parts, the 1,2-pentanediol 0.3 part and the water are accurately weighed according to 100 parts by weight; The physical sunscreen agent is mixed with 18 parts by weight of water, ultrasonically treated at 200 W for 20 min to obtain a physical sunscreen agent dispersion; the chemical sunscreen agent, the tocopherol, the ferulic acid, the steareth-2 and the steareth-2 are mixed, heated at 70°C for 10 min to obtain an oil phase; the remaining water, the glycerol, the betaine, the dimethicone and the 1,2-pentanediol are mixed to obtain an aqueous phase; the oil phase is added to the aqueous phase, homogenized at 10000 rpm for 3 min, then the physical sunscreen agent dispersion is added, homogenized at 5500 rpm for 1.5 min, the light-activated enzyme repair factor, the ginger flower root extract, the white water lily flower extract, the QUERCARE light protection essence and the light damage repair agent are added, stirred at 250 rpm for 18 min, the pH value is adjusted to 6.5, vacuum degassed, sterilized to obtain the cosmetic composition.

[0059] Comparative Example 1 The specific implementation and example 4 are the same, except that the "physical sunscreen agent 8 parts, chemical sunscreen agent 12 parts" is replaced by "physical sunscreen agent 20 parts".

[0060] Comparative Example 2 The specific implementation is the same as that of Example 4, except that the "physical sunscreen 8 parts, chemical sunscreen 12 parts" is replaced by "chemical sunscreen 20 parts", and step (1) is deleted.

[0061] Comparative Example 3 The specific implementation is the same as that of Example 4, except that the physical sunscreen is replaced by nano titanium dioxide, and step (1) is deleted.

[0062] Comparative Example 4 The specific implementation is the same as that of Example 4, except that the chemical sunscreen is composed of homosalate, avobenzone and octocrylene in a weight ratio of 3:2:4.

[0063] Comparative Example 5 The specific implementation is the same as that of Example 4, except that the "60% ethanol solution" in the preparation of the light damage repair agent in step (1) is replaced by water.

[0064] Comparative Example 6 The specific implementation is the same as that of Example 4, except that the Paracasei CICC 25261 in the preparation of the light damage repair agent in step (1) is replaced by Lactobacillus helveticus CICC 22818, and Bifidobacterium adolescentis CICC 24573 is replaced by Bifidobacterium longum CICC 6207, and other conditions remain unchanged.

[0065] Comparative Example 7 The specific implementation is the same as that of Example 4, except that the light damage repair agent is composed of chamomile extract, calendula extract and licorice extract in a weight ratio of 2:3:2.

[0066] Test Example 1 Sunscreen effect test According to the method of 4.2 selection of subjects in the determination method of sunscreen index (SPF value) of sunscreen cosmetics in the cosmetic safety technical specification, 100 subjects were screened out, and divided into 10 groups, 10 people in each group, and there was no significant difference in age and skin condition between groups.

[0067] The SPF value and PFA value of the cosmetic compositions of Examples 4-6 and Comparative Examples 1-7 were determined according to the determination methods of sunscreen index (SPF value) and long-wave ultraviolet protection index (PFA value) of sunscreen cosmetics in the cosmetic safety technical specification, respectively. The specific results are shown in Table 3.

[0068] Table 3 SPF value and PFA value of each group of cosmetic compositions Group SPF value PFA value Example 4 58.7 17.6 Example 5 57.6 16.5 Example 6 58.3 17.2 Comparative Example 1 42.8 11.9 Comparative Example 2 41.1 11.4 Comparative Example 3 50.2 13.8 Comparative Example 4 49.4 13.7 Comparative Example 5 53.0 15.0 Comparative Example 6 52.5 14.3 Comparative Example 7 52.2 14.5 From the results of Table 3, it can be seen that the SPF value and PFA value of the cosmetic composition of the examples are higher than those of the comparative examples. From the comparison of the data of Example 4 and Comparative Examples 1-2, it can be seen that the synergistic combination of physical sunscreen and chemical sunscreen can effectively block and absorb more ultraviolet bands, provide comprehensive UV protection, significantly improve the SPF value and PFA value, and impart stronger sunscreen effect to the cosmetic composition. From the comparison of the data of Example 4 and Comparative Example 3, it can be seen that the modification of nano-titanium dioxide can improve the stability and dispersibility of nano-titanium dioxide, thereby improving the sunscreen effect of the cosmetic composition. From the comparison of the data of Example 4 and Comparative Example 4, it can be seen that the synergistic combination of bis-ethylhexyloxyphenol methoxyphenyl triazine, avobenzone and octocrylene can reduce photodegradation and improve the sunscreen effect. From the comparison of the data of Example 4 and Comparative Examples 5-7, it can be seen that the extraction of different solvents, the fermentation of different microorganisms, and the combination of different ingredients can affect the SPF value and PFA value of the cosmetic composition.

[0069] Test Example 2 UV protection light damage repair effect After the SPF value and PFA value determination of the subjects in Experimental Example 1 was completed, the cosmetic compositions of Examples 4-6 and Comparative Examples 1-7 were applied, respectively. After one week of use, the UV protection light damage repair effect was evaluated, and the subjects were scored on a scale of 10, with 1 (worst) to 10 (best). The average value was taken, and the specific results are shown in Table 4.

[0070] The method for using the cosmetic composition is as follows: after the skin is washed and the basic skin care is completed, take a coin-sized (about 0.9 g) cosmetic composition, and apply it to the cheeks, forehead, nose tip, chin and other five places with fingertips, and massage it evenly in the same direction in a clockwise circle. It can be used after it is formed.

[0071] Table 4 UV protection light damage repair score of each group of cosmetic compositions Group UV protection light damage repair score Group UV protection light damage repair score Example 4 9.5 Comparative Example 3 5.6 Example 5 9.0 Comparative Example 4 6.2 Example 6 9.2 Comparative Example 5 6.8 Comparative Example 1 5.4 Comparative Example 6 6.3 Comparative Example 2 5.0 Comparative Example 7 6.1 From the data in Table 4, it can be seen that the examples can significantly improve the UV protection light damage repair score. From the comparison of the data of Example 4 and Comparative Examples 1-2, it can be seen that the synergistic combination of physical sunscreen and chemical sunscreen can significantly reduce UV light damage, reduce sunburn and photoaging, and thereby improve the light damage repair effect. From the comparison of the data of Example 4 and Comparative Examples 3-4, it can be seen that the modification of nano-titanium dioxide and the adjustment of the composition of the light damage repair agent can improve the UV protection light damage repair effect. From the comparison of the data of Example 4 and Comparative Examples 5-7, it can be seen that the extraction of different solvents, the fermentation of different microorganisms, and the combination of different ingredients can affect the UV protection light damage repair effect of the cosmetic composition.

[0072] The above merely describes the preferred embodiments of the present application, and it should be pointed out that, for those skilled in the art, several improvements and refinements can be made without departing from the principles of the present application, and these improvements and refinements should also be considered as falling within the protection scope of the present application.

Claims

1. A cosmetic composition for broad-spectrum UV protection and cosmetic photoreversal and photodamage repair, characterized in that, It includes photoactivated enzyme repair factor, ginger flower root extract and white water lily extract.

2. The cosmetic composition according to claim 1, characterized in that, The weight ratio of the photoactivated enzyme repair factor, ginger flower root extract and white water lily extract is (0.3-0.5):(4-6):(2-4).

3. The cosmetic composition according to claim 1, characterized in that, It also includes QUERCARE.

4. The cosmetic composition according to claim 3, characterized in that, The weight ratio of QUERCARE light-protecting agent to photoactivated enzyme repair factor, ginger root extract and white water lily extract is (0.3-0.5):(0.3-0.5):(4-6):(2-4).

5. The cosmetic composition according to claim 1, characterized in that, It also includes chemical sunscreens, physical sunscreens, and photodamage repair agents.

6. The cosmetic composition according to claim 5, characterized in that, The photodamage repair agent is composed of rockrose leaf extract, Ganoderma lucidum extract and hydrolyzed red algae extract.

7. The cosmetic composition according to claim 5, characterized in that, Physical sunscreens are composed of titanium dioxide and silica.

8. The cosmetic composition according to claim 1, characterized in that, This also includes acceptable excipients in cosmetics.

9. The use of a cosmetic composition according to any one of claims 1-8 in a sunscreen cosmetic.

10. The use of the cosmetic composition according to any one of claims 1-8 in a photodamage repair cosmetic.