Microdialysis brain tissue monitoring electrode needle

The microdialysis brain tissue monitoring electrode needle, which integrates an electrode needle and a microdialysis probe, solves the data deviation problem of synchronously acquiring electrophysiological and biochemical signals, reduces brain tissue damage and operation time, and improves dialysis efficiency and diagnostic accuracy.

CN121313186BActive Publication Date: 2026-04-14BEIJING TIANTAN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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Patent Information

Application Number
CN202511890484.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-12-15
Publication Date
2026-04-14
Estimated Expiration
2045-12-15

AI Technical Summary

Technical Problem

In existing technologies, intracranial electrode implantation and microdialysis are performed separately, which results in the inability to acquire electrophysiological and biochemical signals synchronously, posing a risk of data analysis bias. Furthermore, multiple operations increase brain tissue damage and prolong the operation time. In addition, the microdialysis probe has a small dialysis membrane area, resulting in low dialysis efficiency.

Method used

A microdialysis brain tissue monitoring electrode needle was designed, integrating the electrode needle with a microdialysis probe to achieve simultaneous acquisition of electrophysiological signals and biochemical information. The rigid electrode needle drives the implantation of the microdialysis probe, increasing the dialysis membrane area, reducing the number of punctures, and improving dialysis efficiency.

Benefits of technology

It achieves precise correlation between electrophysiological and biochemical signals, shortens operation time, reduces brain tissue damage, improves dialysis efficiency, ensures surgical safety, and enhances the accuracy of disease diagnosis.

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Abstract

The application discloses a microdialysis brain tissue monitoring electrode needle, which comprises an electrode needle (10) and a microdialysis probe (20). The electrode needle is a needle body structure extending towards an extension direction, one side of the electrode needle is provided with a first connecting surface (11), and the side opposite to the first connecting surface of the electrode needle is a first working surface (12) provided with an electrode point (13); the microdialysis probe is a tubular structure extending towards an extension direction, a microdialysis catheter (23) is arranged in the microdialysis probe, one side of the microdialysis probe is provided with a second connecting surface (21), and the side opposite to the second connecting surface of the microdialysis probe is a second working surface (22); and along the extension direction, one end of the microdialysis probe is wrapped with a dialysis membrane (25). The device can integrate the electrode needle and the microdialysis probe into one body, realize synchronous collection of the electrophysiological signals and biochemical information of the same brain area, and make the data correlation more accurate.
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