Dialysis bottle with replaceable dialysis membrane

By designing a dialysis membrane replacement structure with a built-in spring clip and screw cap on the dialysis bottle, the problem of the inability to quickly replace the dialysis membrane in existing dialysis bottles is solved, realizing the rapid disassembly and sealing of the dialysis membrane and improving the flexibility and efficiency of experiments.

CN224126984UActive Publication Date: 2026-04-17SIMO FEI BIOTECHNOLOGY (SHANGHAI) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SIMO FEI BIOTECHNOLOGY (SHANGHAI) CO LTD
Filing Date
2025-05-15
Publication Date
2026-04-17

AI Technical Summary

Technical Problem

Existing dialysis bottles cannot quickly replace dialysis membranes, making it difficult to meet diverse experimental needs and limiting experimental efficiency and flexibility.

Method used

A dialysis bottle with a replaceable dialysis membrane was designed. It adopts a spring clip design on the left and right side cover plates, combined with a screw cap and a floating foam, to achieve quick disassembly and sealing of the dialysis membrane, avoiding the cumbersome operation of traditional methods and damage to the dialysis bag.

Benefits of technology

It enables rapid replacement of dialysis membranes, meets different experimental needs, improves experimental efficiency, avoids inconvenience in sealing and damage to dialysis bags, and ensures the stability and flexibility of the dialysis process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of dialysis bottles, in particular to a dialysis bottle with a replaceable dialysis membrane, which comprises a main body, the main body comprises a frame structure and a bottle cap connecting part, the middle of the frame structure is a hollow structure, and grooves are arranged on the front side and the rear side of the frame structure; the bottle cap is connected with the bottle cap connecting part of the main body; the cover plate presses the sealing ring into the groove of the frame structure, the dialysis membrane is extruded and sealed, a buckle is arranged on one side of the cover plate, the end of the buckle is of a U-shaped structure, the end of the U-shaped structure is provided with a protruding structure, the other side of the cover plate is provided with a connecting part matched with the buckle, and the buckle is matched with the connecting part and provided with a channel. According to the utility model, rapid disassembly and assembly can be realized, the dialysis membrane can be selectively replaced, and different requirements of users can be met; the problems that a traditional dialysis bag depends on a dialysis clamp or a knot or other methods for sealing in the using process, operation is tedious, and the dialysis bag is prone to being damaged are solved; and the liquid to be dialyzed can be in a better suspension state in the buffer solution.
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Description

Technical Field

[0001] This utility model relates to the field of dialysis bottle technology, specifically to a dialysis bottle with a replaceable dialysis membrane. Background Technology

[0002] Dialysis is one of the simplest and most commonly used separation and purification techniques in biochemistry laboratories. It is used in the preparation of biomolecules for desalting, removing small amounts of organic solvents, removing small biomolecule impurities, and concentrating samples. Dialysis can be performed using a specialized semi-permeable membrane, typically made into a bag shape. The biomolecule solution is placed inside the bag, which is then immersed in water or a buffer solution. Large biomolecules in the sample solution are retained inside the bag, while salts and small molecules diffuse through the membrane until the concentrations on both sides reach equilibrium. The driving force of dialysis is the diffusion pressure, which is formed by the concentration gradient across the membrane.

[0003] Different experimental needs often require the selection of dialysis bottles of different specifications. Existing dialysis bottles usually cannot quickly replace the dialysis membrane, which makes it difficult to flexibly meet the diverse needs of users during dialysis, thus limiting the efficiency and flexibility of the experiment. Summary of the Invention

[0004] The purpose of this invention is to solve the problem that existing dialysis bottles cannot be quickly disassembled and reassembled during use, and that dialysis membranes cannot be selected and replaced according to different needs.

[0005] To achieve the above objectives, this utility model provides a dialysis bottle with a replaceable dialysis membrane, comprising a main body, the main body including a frame structure and a bottle cap connecting part connected to the top of the frame structure, the middle part of the frame structure being a hollow structure, and grooves being provided on both the front and rear sides of the frame structure.

[0006] The bottle cap is threadedly connected to the bottle cap connection part of the main body;

[0007] The system consists of two cover plates, a sealing ring, and a dialysis membrane. The two cover plates press the sealing ring into the front and rear grooves of the main frame structure. The dialysis membrane is sealed by the cover plates and the sealing ring. One side of the cover plate has several buckles with U-shaped ends. The ends of the U-shaped structures have protrusions extending outward. The other side of the cover plate has a connecting part that engages with the buckles. The buckle-engaging connecting part has a channel that allows the buckles to pass through while restricting the passage of the buckle protrusions.

[0008] Preferably, the bottle cap connecting part has a boss in the middle, and the upper part of the boss has a thread for connecting the bottle cap. The bottle cap connects to the float foam, and the float foam has holes for locking at the bottle cap so that the dialysis bottle can float in the buffer solution.

[0009] Preferably, the cover plate includes a first cover plate and a second cover plate, the first cover plate and the second cover plate are the same shape and are arranged in opposite directions, the first cover plate has a hollow structure in the middle, and the periphery of the first cover plate is provided with an extension portion towards the main body, and the top of the extension portion is also provided with an arc-shaped notch for matching the bottle cap connection portion of the main body.

[0010] Preferably, the sealing ring includes a first sealing ring and a second sealing ring, the first sealing ring and the second sealing ring having the same shape and fitting into the groove of the main frame structure.

[0011] Preferably, the interior of the bottle cap connecting part is a hollow structure channel, and the hollow structure channel is connected to the hollow structure of the frame structure.

[0012] Compared with the prior art, the advantages of this utility model are:

[0013] This utility model features a snap-on design with built-in spring clips on both sides of the cover, enabling quick assembly and disassembly. The dialysis membrane can be selected and replaced according to different needs, meeting the diverse requirements of users. The screw cap design avoids many problems associated with traditional dialysis bags, such as relying on dialysis clips or knots for sealing, cumbersome operation, and easy damage to the dialysis bag. The cap, by matching the appropriate float foam, ensures that the dialysis fluid maintains a good suspension state in the buffer solution. Attached Figure Description

[0014] Figure 1 A schematic diagram of the overall structure of a dialysis bottle with a replaceable dialysis membrane provided by this utility model;

[0015] Figure 2 A schematic diagram of the main structure of a dialysis bottle with a replaceable dialysis membrane provided by this utility model;

[0016] Figure 3 A schematic diagram of a dialysis bottle cap plate with a replaceable dialysis membrane provided by this utility model;

[0017] Figure 4 A left-side view of a dialysis bottle cap with a replaceable dialysis membrane provided by this utility model;

[0018] Figure 5 A schematic diagram of a dialysis bottle cap structure for a replaceable dialysis membrane provided by this utility model;

[0019] Figure 6 A schematic diagram of a dialysis bottle sealing ring structure for a replaceable dialysis membrane provided by this utility model;

[0020] Figure 7 A schematic diagram of the float foam structure of a dialysis bottle with a replaceable dialysis membrane provided by this utility model.

[0021] The components are: 1. Main body; 2. Frame structure; 3. Bottle cap connection part; 4. Bottle cap; 5. Cover plate; 6. Sealing ring; 7. Dialysis membrane; 8. Buckle; 9. Buckle mating connection part; 10. Boss; 11. Float foam. Detailed Implementation

[0022] To make the purpose, principle and structure of this utility model clearer, the following description is provided in conjunction with the accompanying drawings and specific embodiments.

[0023] See Figure 1 , Figure 2 This embodiment provides a dialysis bottle with a replaceable dialysis membrane, including a main body 1 and two cover plates 5. The main body 1 includes a rectangular frame structure 2 and a bottle cap connecting part 3 fixedly connected to the upper part of the frame structure 2. The rectangular frame structure 2 is hollow in the middle and has grooves on both the front and rear sides. The bottle cap connecting part 3 is a cylindrical structure with an internal hollow structure. The internal hollow channel of the bottle cap connecting part 3 is connected to the hollow structure of the frame structure 2. An annular boss 9 is provided in the middle of the outer side. Threads are provided above the outer boss 9 of the bottle cap connecting part 3.

[0024] See Figure 1 , Figure 3 , Figure 4 The two cover plates 5 are divided into a first cover plate and a second cover plate. The first cover plate and the second cover plate have the same shape as the main frame structure 2. Taking one of the cover plates 5 as an example, the middle of the cover plate 5 is hollow. The cover plate 5 has an extension part on the periphery towards the main body 1. The top of the extension part has an arc-shaped notch for matching the bottle cap connecting part 3 of the main body. The inner size of the extension part is basically consistent with the outer size of the main frame structure 2. The left side of the cover plate 5 has two identical buckles 8 arranged vertically and horizontally. The buckles 8 have a U-shaped structure and a spring sheet. The opening end of the U-shaped structure has a protruding structure extending vertically and horizontally outward. The right side of the cover plate 5 has a connecting part that matches the buckles 8. The buckle matching connecting part 9 is a rectangular structure with a hollow middle part. The hollow middle part allows the buckles 8 to pass through and restricts the protruding structure of the buckles 8. The other cover plate 5 is arranged in the opposite direction. The buckle 8 of the cover plate 5 is designed to facilitate the disassembly and replacement of the dialysis membrane 7.

[0025] See Figure 1 , Figure 5 The bottle cap 5 is designed to mate with the bottle cap connecting part 3. It has a cylindrical structure and the inner side is provided with threads that mate with the bottle cap connecting part 3. This is used for adding and removing the dialysis fluid, avoiding the problem of repeated disassembly of traditional dialysis bags and making it convenient to use.

[0026] See Figure 1 , Figure 6The two cover plates 5 press the sealing ring 6 into the front and rear grooves of the main frame structure 2. The dialysis membrane 7 achieves end face compression sealing through the cover plates 5 and the sealing ring 6 to prevent leakage of the dialysis fluid. The sealing ring 6 includes a first sealing ring and a second sealing ring. The first sealing ring and the second sealing ring have the same shape and match the groove of the main frame structure 2. The dialysis membrane 7 can be replaced by removing the cover plates 5 on both sides, so that the dialysis bottle is a non-disposable product.

[0027] See Figure 1 , Figure 7 The float foam 11 has a ring structure, and the size of the inner ring is consistent with the size of the bottle cap 4. The shape of the float foam 11 can also be selected according to the actual situation. The float foam 11 is used to lock at the bottle cap 4, so that the dialysis bottle after adding liquid floats in the buffer solution through the float foam 11 for dialysis experiments.

[0028] The above description is merely a specific embodiment of this utility model, but the scope of this utility model is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the technical scope disclosed in this utility model, based on the technical solution and novel concept of this utility model, should be covered within the protection scope of this utility model.

Claims

1. A dialysis bottle with a replaceable dialysis membrane, characterized in that... include The main body includes a frame structure and a bottle cap connecting part connected to the top of the frame structure. The middle part of the frame structure is a hollow structure, and the front and rear sides of the frame structure are provided with grooves. The bottle cap is threadedly connected to the bottle cap connection part of the main body; The system consists of two cover plates, a sealing ring, and a dialysis membrane. The two cover plates press the sealing ring into the front and rear grooves of the main frame structure. The dialysis membrane is sealed by the cover plates and the sealing ring. One side of the cover plate has several buckles with U-shaped ends. The ends of the U-shaped structures have protrusions extending outward. The other side of the cover plate has a connecting part that engages with the buckles. The buckle-engaging connecting part has a channel that allows the buckles to pass through while restricting the passage of the buckle protrusions.

2. The dialysis bottle with replaceable dialysis membrane as claimed in claim 1, characterized in that The bottle cap connection part has a boss in the middle, and the upper part of the boss has a thread for connecting the bottle cap. The bottle cap connects to the float foam, and the float foam has holes for locking at the bottle cap so that the dialysis bottle can float in the buffer solution.

3. A dialysis bottle with a replaceable dialysis membrane as described in claim 1, characterized in that... The cover plate includes a first cover plate and a second cover plate. The first cover plate and the second cover plate have the same shape and are arranged in opposite directions. The first cover plate has a hollow structure in the middle and an extension extending towards the main body on the periphery. The top of the extension is also provided with an arc-shaped notch for matching the bottle cap connection part of the main body.

4. The dialysis bottle with replaceable dialysis membrane as claimed in claim 1, characterized in that The sealing ring includes a first sealing ring and a second sealing ring, which have the same shape and fit into the groove of the main frame structure.

5. The dialysis bottle with replaceable dialysis membrane as claimed in claim 1, characterized in that The interior of the bottle cap connector is a hollow structure channel, which is connected to the hollow structure of the frame structure.