Tumor electric field treatment system

Abstract

The invention provides a tumor electric field treatment system which comprises an electrode plate and a controller, the electrode plate comprises a plurality of electrode units and a handshake chip, and each electrode unit comprises a dielectric element and a temperature sensor with a signal end and a grounding end. The plurality of electrode units are arranged in at least two rows and two columns on the circuit, the grounding ends of the temperature sensors in the same row are in short circuit through the same path of grounding wire, and the signal ends of the temperature sensors in the same column group are in short circuit through the same path of dual-purpose signal wire. The dual-purpose signal line is configured to transmit an alternating current signal to the corresponding dielectric element in a first mode, and transmit a direct current signal or a temperature signal detected by the corresponding temperature sensor to the signal end of the corresponding temperature sensor in a second mode. The controller is configured to communicate with the handshake chip so as to judge the connection state of the electrode slices, and is configured to combine and control the states of the grounding wire and the dual-purpose signal line when the electrode slices are normally connected so as to enable the dual-purpose signal line to be switched between transmission of an alternating current electric signal and transmission of a temperature detection signal.

Description

[0001] This application is a divisional application of the application No. CN202411499210.X, filed on October 25, 2024, with the title of "Electrode Sheet, Tumor Electric Field Treatment System and Temperature Detection and Signal Control Method". TECHNICAL FIELD

[0002] The present application relates to the tumor electric field treatment (TTF) technology, and in particular to a tumor electric field treatment system. BACKGROUND

[0003] Tumor electric field treatment is a method for treating tumors by preventing the formation of spindle microtubules in the mitotic process of certain tumor cells, inhibiting the separation of intracellular organelles in the cell division phase, and inducing apoptosis of cells in the mitotic phase.

[0004] Compared with traditional cancer treatment methods, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometry and high-frequency mitosis, make them susceptible to TTF. TTF disrupts the normal aggregation of tubulin by exerting a directional force on intracellular polar particles (such as macromolecules and organelles). These processes can lead to physical disruption of the cell membrane and apoptosis. At the end of the cell mitosis, the structure of the cleavage furrow leads to uneven distribution of the electric field around it, and under the influence of TTF, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move towards the cleavage furrow, which interferes with the formation of the cell structure and even destroys it, ultimately leading to cell division failure and apoptosis.

[0005] In existing tumor electric field treatment systems, an electric field generating device is used to transmit an alternating current signal for tumor electric field treatment to an electrode sheet, and then an alternating electric field is applied to the tumor site of a patient through the electrode sheet for tumor electric field treatment. When the tumor treatment electric field is applied to the patient's body, heat will accumulate at the application site, and the temperature will also rise accordingly. Therefore, it is necessary to monitor the temperature at the application site, and when the temperature is too high, the electric field intensity needs to be adjusted in time to avoid the risk of skin burns caused by excessive temperature.

[0006] The tumor electric field treatment system includes at least one pair of electrode sheets, and each electrode sheet has a plurality of electrode units. Even if the same alternating current signal is applied to each electrode unit, the heat generated on each electrode unit will be different due to the different positions of the electrode units, that is, the temperature of each electrode unit on the entire electrode sheet will not be completely uniform. Thus, the temperature of some electrode units on the entire electrode sheet can exceed the preset temperature, while the temperature of other electrode units is normal. In order to ensure that the tumor electric field treatment has a long enough application time while avoiding causing low-temperature burns on the patient's body surface, individual control needs to be implemented on the over-temperature electrode units. However, for the existing electrode sheet, in order to implement individual control on the electrode units, a conductive trace needs to be arranged in the substrate of the electrode sheet for each electrode unit. Thus, the conductive traces in the electrode sheet substrate will increase, so that the electrode sheet is not easy to bend, and the cable electrically connected to the electrode sheet will also be thickened, so that the overall weight of the electrode sheet is increased, which is not conducive to the application of the electrode sheet.

[0007] Therefore, it is necessary to provide an improved tumor electric field treatment system. SUMMARY

[0008] The purpose of the present application is to provide a tumor electric field treatment system provided with an electrode sheet having a handshake chip.

[0009] To achieve the above object, the present application provides the following technical solution: A tumor electric field treatment system, comprising: an electrode sheet, the electrode sheet comprising a flexible circuit board and a plurality of electrode units and a handshake chip provided on the flexible circuit board, the electrode unit comprising a dielectric element and a temperature sensor having a signal end and a ground end, the flexible circuit board being provided with a plurality of ground lines connected to each of the ground ends and a plurality of dual-purpose signal lines connected to each of the signal ends, and the dielectric element and the signal end of the temperature sensor are short-circuited, a plurality of the electrode units are arranged in at least two rows and two columns in the circuit, the ground ends of the temperature sensors in the same row group are short-circuited through the same ground line, and the ground ends of the temperature sensors in different row groups are connected in parallel through different ground lines respectively; the signal ends of the temperature sensors in the same column group are short-circuited through the same dual-purpose signal line, and the signal ends of the temperature sensors in different column groups are connected in parallel through different dual-purpose signal lines respectively; each of the dual-purpose signal lines is configured to transmit an alternating current signal to the dielectric element of each of the electrode units in the corresponding column group in a first mode, and transmit a direct current signal to the signal end of the temperature sensor of each of the electrode units in the corresponding column group or transmit a temperature signal detected by the temperature sensor of each of the electrode units in the corresponding column group in a second mode; and a controller configured to communicate with the handshake chip to determine the connection state of the electrode sheet, and configured to combine the states of the ground lines and the dual-purpose signal lines of the electrode sheet to switch the dual-purpose signal lines between transmitting alternating current signals and transmitting temperature detection signals in the case of normal connection of the electrode sheet.

[0010] Further, the controller is configured to send a handshake signal to the handshake chip and determine whether the electrode sheet is normally connected according to whether feedback from the handshake chip is received.

[0011] Further, the controller is further configured to control or adjust the alternating current signal transmitted to the dual-purpose signal line according to the temperature detection signal of each of the electrode units obtained by detection.

[0012] Further, the controller is further configured to determine the working state of each of the electrode units according to the temperature detection signal of each of the electrode units obtained by detection, the working state comprising continuing to apply an alternating current signal or stopping applying an alternating current signal.

[0013] Further, the system has a preset temperature threshold.

[0014] Further, the controller is further configured to compare the temperature detection signal of each of the electrode units obtained with the preset temperature threshold; and control or adjust the alternating current signal transmitted to the dual-purpose signal line according to the comparison result.

[0015] Further, the controller is configured to continue to apply the alternating current signal to each electrode unit of the electrode sheet when none of the acquired temperature detection signals of each electrode unit of the electrode sheet exceeds the preset temperature threshold, or to stop applying the alternating current signal to the electrode units of the electrode sheet when one of the acquired temperature detection signals of each electrode unit of the electrode sheet exceeds the preset temperature threshold.

[0016] Further, the comparison result includes not exceeding the preset temperature threshold and exceeding the preset temperature threshold, the not exceeding the preset temperature threshold includes being far below the preset temperature threshold and being close to the preset temperature threshold, and the controller is further configured to continue to transmit the alternating current signal to the dual-purpose signal line in the following manner when none of the temperature detection signals of each electrode unit exceeds the preset temperature threshold: continuing to transmit the alternating current signal to the dual-purpose signal line in a manner of increasing the voltage or current or power amplitude of the alternating current signal currently transmitted to the dual-purpose signal line or in a manner of keeping the voltage or current or power amplitude of the alternating current signal currently transmitted to the dual-purpose signal line unchanged when the temperature detection signal is far below the preset temperature threshold; or continuing to transmit the alternating current signal to the dual-purpose signal line in a manner of keeping the voltage or current or power amplitude of the alternating current signal currently transmitted to the dual-purpose signal line unchanged or in a manner of decreasing the voltage or current or power amplitude of the alternating current signal currently transmitted to the dual-purpose signal line when the temperature detection signal is close to the preset temperature threshold.

[0017] Further, the controller is further configured to determine the type of the electrode sheet according to the temperature detection signals of each electrode unit, or to determine whether the electrode sheet has temperature abnormality according to the temperature detection signals of each electrode unit, or to determine whether the temperature sensor of the electrode sheet has failure according to the temperature detection signals of each electrode unit, or to determine whether the electrode unit of the electrode sheet has over-temperature according to the temperature detection signals of each electrode unit.

[0018] Further, the controller is further configured to determine whether the electrode sheet needs to be replaced according to the failure condition of the temperature sensor of the electrode sheet.

[0019] The above description is only a summary of the technical solutions of the present application. In order to more clearly understand the technical means of the present application, the present application can be implemented according to the content of the specification, and in order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the following specific embodiments of the present application are described. BRIEF DESCRIPTION OF DRAWINGS

[0020] Figure 1This is a schematic diagram of a tumor electric field therapy system according to an embodiment of the present application, which shows a schematic diagram of the spatial structure of the electrode sheet of the first embodiment;

[0021] Figure 2 For use in this application Figure 1 A schematic diagram of the structural layout of a modified embodiment of the electrode sheet of the first embodiment of the tumor electric field therapy system shown;

[0022] Figure 3 For this application Figure 1 The circuit connection diagram of the tumor electric field system shown illustrates... Figure 1 The electrode sheet of the first embodiment shown Figure 2 The electrode sheet of the transformation embodiment shown is Figure 1 A circuit connection diagram of the adapter of the first embodiment shown in the figure;

[0023] Figure 4 For this application Figure 3 A schematic block diagram of the internal structure of the adapter shown;

[0024] Figure 5 For this application Figure 1 A schematic block diagram of the internal structure of the electric field generator in the tumor electric field therapy system is shown.

[0025] Figure 6 and Figure 3 Similarly, a circuit connection diagram of the tumor electric field therapy system according to the second embodiment of this application is shown, illustrating the electrode sheet used in the second embodiment of the tumor electric field therapy system of this application and... Figure 3 The circuit connection diagram of the adapter is shown below;

[0026] Figure 7 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field therapy system according to the third embodiment of this application shows the electrode sheet and... Figure 3 The circuit connection diagram of the adapter is shown below;

[0027] Figure 8 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field therapy system according to the fourth embodiment of this application shows the electrode sheet and... Figure 3 The circuit connection diagram of the adapter is shown below;

[0028] Figure 9 and Figure 3 Similarly, the circuit connection diagram of the tumor electric field therapy system according to the fifth embodiment of this application shows the electrode sheet and...Figure 3 Circuit connection diagram of the adapter shown;

[0029] Figure 10 Flowchart of the temperature detection method of the tumor electric field treatment system of the present application;

[0030] Figure 11 Workflow diagram of the tumor electric field treatment system of the present application;

[0031] Figure 12 Another flowchart of the temperature detection method of the tumor electric field treatment system of the present application;

[0032] Figure 13 Flowchart of the AC signal application control method for the tumor electric field treatment of the present application;

[0033] Figure 14 Flowchart of the signal control method for the tumor electric field treatment of the present application;

[0034] Figure 15 Flowchart of the electrode sheet temperature detection method of the present application;

[0035] Figure 16 Flowchart of the AC signal application method for the tumor electric field treatment of the present application.

[0036] Explanation of reference numerals:

[0037] The tumor electric field treatment system 100, the electrode sheet 10, 10', 10D, 10E, 10F, 10H, the flexible circuit board 11, 11D, 11E, 11F, 11H, the connecting part 111, 111', the wiring part 112, 112', the bridging part 113, 113', the main stem 114, 114', the branch 115, 115', the first interval D1, D1', the second interval D2, D2', the electrode unit 12, 12', the first cable 13, 13', the temperature sensor 14, the ground end 14-1, the signal end 14-2, the dielectric element 15, the diode 16, the handshake chip 17, the ground trace 171, the communication line 172, the ground line 18, the first ground line 18-1, the second ground line 18-2, the third ground line 18-3, the fourth ground line 18-4, the dual-purpose signal line 19, the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, the fifth dual-purpose signal line 19-5, the adapter 20, the second cable 21, the first controller 22, the analog-to-digital converter 23, the voltage dividing resistor 24, the ground switch 25, the first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, the fourth ground switch 25-4, the bidirectional switch 26, the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, the fifth bidirectional switch 26-5, the first communication unit 27, the AC signal line 28, the first power module 29, the communication transmission line 211, the electric field generator 30, the second power module 31, the second controller 32, the second communication unit 33, the AC signal generator 34, the AC signal switch 35, the first AC signal switch 35-1, the first AC signal switch 35-2, the first AC signal switch 35-3, the first AC signal switch 35-4, the first connector 40, 40D, 40E, 40F, 40H, the first plug 41, 41', the first socket 42, the second connector 50, the second plug 51, the second socket 52. DETAILED DESCRIPTION

[0038] The embodiments of the technical scheme of the present application will be described in detail below with reference to the drawings. The following embodiments are only used to more clearly illustrate the technical scheme of the present application, and therefore only serve as examples, and cannot limit the protection scope of the present application.

[0039] Figure 1 The tumor electric field treatment system 100 of an embodiment of the present application is shown in the schematic diagram. As shown in the figure, Figure 1As shown, the tumor electric field treatment system 100 comprises at least one pair of electrode patches 10, an adapter 20 connected with the electrode patches 10, and an electric field generator 30 connected with the adapter 20. The electric field generator 30 generates an alternating current signal for tumor treatment and applies the alternating current signal to the electrode patches 10 through the adapter 20, so that a treatment electric field is generated between the electrode patches 10 arranged in pairs. The adapter 20 is electrically connected between the electrode patches 10 and the electric field generator 30, and is used to transmit the alternating current signal generated by the electric field generator 30 to the electrode patches 10. That is, the electric field generator 30 can generate an alternating current signal, and the alternating current signal generated thereby is transmitted to each electrode patch 10 through the adapter 20, so that a treatment electric field for treating a tumor is generated between the same pair of electrode patches 10. As shown in the figure, the adapter 20 comprises a plurality of adapters 20 arranged in pairs, and each adapter 20 is electrically connected between two electrode patches 10. The adapter 20 is used to transmit the alternating current signal generated by the electric field generator 30 to the electrode patches 10. The adapter 20 can be a cable or a printed circuit board (PCB) with a plurality of conductive lines. Figure 1 As shown, in the embodiment, the number of electrode patches 10 is four. From the spatial structure arrangement, each electrode patch 10 comprises a plurality of electrode units 12 arranged in axial symmetry and central symmetry, a plurality of connecting portions 111 between adjacent two electrode units 12, a bridging portion 113 arranged between adjacent two connecting portions 111, a wiring portion 112 connected with the bridging portion 113, and a first cable 13 connected with the wiring portion 112. The bridging portion 113 and the wiring portion 112 are arranged in a vertical manner, forming a "T" shape. The bridging portion 113 is arranged between adjacent two connecting portions 111. Each electrode unit 12 of the electrode patch 10 is electrically connected to the adapter 20 through the first cable 13 with 10-core conductive lines.

[0040] Each electrode unit 12 has a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature of the part of the patient's body surface to which the electrode unit 12 is attached, which can be a thermistor element or other temperature sensor except thermistor, and can be arranged at any position on the electrode unit 12. The dielectric element 15 is used to apply an alternating current signal to the tumor part of the patient. The dielectric element 15 can be a dielectric ceramic sheet or a high polymer dielectric layer composed of a high polymer material. In the embodiment, each dielectric element 15 has a through hole (not labeled) arranged in the middle for accommodating a corresponding temperature sensor 14. Each electrode unit 12 can further comprise a diode 16 connected in series with the temperature sensor 14, which can prevent the reverse flow of current to prevent the detection signal from other electrode units 12 from affecting the temperature sensor 14. The ground end 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16, and is grounded through the cathode of the diode 16.

[0041] The electrode unit 12 applies an alternating current signal through the dielectric element 15 in the first mode, detects or collects the temperature of the patient's body surface to which the electrode unit 12 is attached through the temperature sensor 14 in the second mode, and stops applying the alternating current signal and stops temperature detection and collection in the third mode. The first mode, the second mode, and the third mode do not overlap in time periods. That is, the time period in which the dielectric element 15 of the electrode unit 12 applies the alternating current signal and the time period in which the temperature sensor 14 of the electrode unit 12 detects the temperature are staggered and do not overlap. The electrode unit 12 can be cyclically switched between applying the alternating current signal through the dielectric element 15 and detecting the temperature through the temperature sensor 14, that is, the electrode unit 12 can be cyclically switched between the first mode and the second mode. The electrode unit 12 can also be cyclically switched between the first mode, the second mode, and the third mode, that is, the electrode unit 12 is cyclically switched between applying the alternating current signal through the dielectric element 15, collecting or detecting the temperature through the temperature sensor 14, and stopping the application of the alternating current signal and the collection of the temperature.

[0042] Each electrode sheet 10 includes an electrode array (not numbered) composed of 20 electrode units 12. The electrode array (not numbered) also has a flexible circuit board 11 including connection portions 111, wiring portions 112, and bridge portions 113. The 20 electrode units 12 are distributed in the electrode array (not numbered) arranged in four rows and six columns in a spaced-apart manner. Specifically, four electrode units 12 are arranged in each of the first and last rows, and six electrode units 12 are arranged in each of the two middle rows. The four electrode units 12 in the first row are arranged in the second to fifth columns, respectively. The six electrode units 12 in each of the two middle rows are arranged in the first to sixth columns, respectively. The four electrode units 12 in the last row are also arranged in the second to fifth columns, respectively. The connection portions 111 are arranged only between adjacent electrode units 12 in the third and fourth columns in the column direction and between adjacent electrode units 12 in each row except for the two electrode units 12 in the third and fourth columns in each row in the row direction. That is, the two electrode units 12 adjacent in the third and fourth columns are connected only in the column direction by the connection portions 111, and are arranged in a disconnected manner in the row direction without being connected by the connection portions 111. The electrode units 12 in the first, second, fifth, and sixth columns are connected only to the electrode units 12 adjacent in the row direction by the connection portions 111 arranged in the transverse direction, and are arranged in a disconnected manner in the column direction from the electrode units 12 adjacent in the column direction. That is, the two electrode units 12 adjacent in the column direction in the first, second, fifth, and sixth columns are arranged in a disconnected manner.

[0043] The electrode units 12 in the third column and the connecting portions 111 longitudinally arranged between the electrode units 12 in the third column, and the electrode units 12 in the fourth column and the connecting portions 111 longitudinally arranged between the electrode units 12 in the fourth column, constitute a stem 114 of the electrode array (not labeled). The connecting portions 111 transversely arranged between the electrode units 12 in the third and fourth columns and the electrode units 12 connected to the connecting portions 111 in the third and fourth columns, and the electrode units 12 connected to the connecting portions 111 transversely arranged, constitute branches 115 of the electrode array (not labeled). That is, in the present embodiment, the electrode array (not labeled) includes two stems 114 and a plurality of branches 115 laterally extending from the two stems 114. Each branch 115 has a free end away from the stem 114, the free ends of adjacent branches 115 are arranged in a broken manner, and the positions and distances between adjacent branches 115 can be freely adjusted according to actual use scenarios. Specifically, one stem 114 is composed of the electrode units 12 in the third column and the connecting portions 111 longitudinally arranged between the electrode units 12 in the third column, and the other stem 114 is composed of the electrode units 12 in the fourth column and the connecting portions 111 longitudinally arranged between the electrode units 12 in the fourth column. The remaining electrode units 12 connected to the connecting portions 111 in the stems 114 and the connecting portions 111 transversely arranged are branches 115.

[0044] Specifically, the branches 115 are respectively: a branch 115 extending laterally leftward from the electrode unit 12 in the third column in the first row and connecting to the electrode unit 12 in the first row in the second column; two branches 115 extending laterally leftward from the electrode units 12 in the third column in the second row and connecting to the electrode units 12 in the first column in the second row and the second column in the second row; two branches 115 extending laterally leftward from the electrode units 12 in the third column in the third row and connecting to the electrode units 12 in the first column in the third row and the second column in the third row; a branch 115 extending laterally leftward from the electrode unit 12 in the third column in the fourth row and connecting to the electrode unit 12 in the second column in the fourth row; a branch 115 extending laterally rightward from the electrode unit 12 in the fourth column in the first row and connecting to the electrode unit 12 in the fifth column in the first row; two branches 115 extending laterally rightward from the electrode units 12 in the fourth column in the second row and connecting to the electrode units 12 in the fifth column in the second row and the sixth column in the second row; two branches 115 extending laterally rightward from the electrode units 12 in the fourth column in the third row and connecting to the electrode units 12 in the fifth column in the third row and the sixth column in the third row; and a branch 115 extending laterally rightward from the electrode unit 12 in the fourth column in the fourth row and connecting to the electrode unit 12 in the fifth column in the fourth row.

[0045] The electrode array (not shown) is divided into a left portion including the left three columns and a right portion including the right three columns, and the left portion and the right portion are connected only by the bridge 113. The left portion is composed of the stem 114 in the third column and the branches 115 extending laterally leftward from the stem 114, and the right portion is composed of the stem 114 in the fourth column and the branches 115 extending laterally rightward from the stem 115. The two stems 114 are connected by the bridge 113 erected therebetween. Specifically, the two stems 114 are connected by the bridge 113 erected between the connection portion 111 connecting the electrode unit 12 in the second row in the third column and the electrode unit 12 in the third row in the third column and the connection portion 111 connecting the electrode unit 12 in the second row in the fourth column and the electrode unit 12 in the third row in the fourth column. The connection portion 111 connecting the electrode unit 12 in the second row in the third column and the electrode unit 12 in the third row in the third column, the connection portion 111 connecting the electrode unit 12 in the second row in the fourth column and the electrode unit 12 in the third row in the fourth column, and the bridge 113 are arranged in a substantially "H" shape. In other embodiments, the bridge 113 can also be erected between an electrode unit 12 in the third column and an electrode unit 12 in the fourth column. Alternatively, the bridge 113 is erected between two electrode units 12 in the third column, the fourth column, and adjacent rows.

[0046] The electrode units 12 are divided into peripheral electrode units 12 and central electrode units 12 according to their positions in the electrode array (not labeled). The peripheral electrode units 12 include the four electrode units 12 in the first row, the two electrode units 12 at opposite ends of the second row, the two electrode units 12 at opposite ends of the third row, and the four electrode units 12 in the fourth row. The central electrode units 12 include the four electrode units 12 in the middle of the second row and the four electrode units 12 in the middle of the third row. Some adjacent electrode units 12 among the peripheral electrode units 12 are connected by the transversely arranged connecting portions 111, and some adjacent electrode units 12 are arranged in a disconnected manner. The adjacent electrode units 12 among the peripheral electrode units 12 connected by the connecting portions 111 are partially row-adjacent electrode units 12. Specifically, among the peripheral electrode units 12, the column-adjacent electrode units 12 and the obliquely-adjacent electrode units 12 are arranged in a disconnected manner, and some of the row-adjacent electrode units 12 are also arranged in a disconnected manner, and only some of the row-adjacent electrode units 12 are connected by the transversely extending connecting portions 111. Among the central electrode units 12, only the column-adjacent electrode units 12 on the main stems 114 are connected by the longitudinally arranged connecting portions 111, and only the row-adjacent electrode units 12 on the branches 115 are connected by the transversely arranged connecting portions 111.

[0047] The electrode array (not labeled) also has intervals (not labeled) formed between some of the spaced electrode units 12, which allow moisture to escape from the patient's body surface, allow the patient's skin to exchange heat with the outside world, or allow the patient's skin to breathe freely, and also allow the branches 115 to freely adjust their positions and distances, and can also avoid wrinkles when the electrode patch 10 is attached. The intervals (not labeled) include first intervals D1 between the two main stems 114 and second intervals D2 between the branches 115. The first intervals D1 are between the third column of electrode units 12 and the fourth column of electrode units 12, and the second intervals D2 are between the electrode units 12 of adjacent rows. That is, along the row, the electrode units 12 in the third column and the adjacent electrode units 12 in the fourth column are disconnected, and no connecting portions 111 are provided but the first intervals D1 are formed; and along the column, only the two electrode units 12 in the third column and the fourth column are connected by the connecting portions 111, and the two electrode units 12 in each of the other four columns are not connected by the connecting portions 111 but the second intervals D2 are formed. The provision of the first and second intervals D1 and D2 can increase the freedom of some of the electrode units 12 and also avoid wrinkles when the electrode patch 10 is attached.

[0048] The electrode sheet 10 also includes a handshake chip 17 disposed on the flexible circuit board 11 and used to confirm the connection state thereof. The handshake chip 17 can communicate with the electric field generator 30 through the adapter 20 to determine the connection state between the electrode sheet 10 and the adapter 20. The electric field generator 30 of the tumor electric field treatment system 100 first sends a handshake communication signal to the handshake chip 17 of the electrode sheet 10 through the adapter 20, and determines the connection state of the electrode sheet 10 according to whether the feedback from the handshake chip 17 is received. The electric field generator 30 of the tumor electric field treatment system 100 applies an alternating current signal to the dielectric element 15 of the electrode sheet 10 or transmits a direct current signal to each temperature sensor 14 of the electrode sheet 10 to collect the temperature detection signal after confirming that the electrode sheet 10 is connected normally through the handshake chip 17. The handshake chip 17 can be an EEPROM with encryption function.

[0049] In some other embodiments, the tumor electric field treatment system 100 can also have more or fewer electrode sheets 10. In some other embodiments, each pair of electrode sheets 10 has the same or different number of electrode units 12, and different pairs of electrode sheets 10 can also have different numbers of electrode units 12. In some other embodiments, the 20 electrode units 12 can also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 10 can also have other numbers of electrode units 12. In some other embodiments, the 20 electrode units 12 can also be arranged in other ways, such as the electrode sheet 10' shown. Figure 2 Of course, in some other embodiments, the electrode sheet 10 can also have other numbers of electrode units 12. In summary, the implementation of the present application is not limited by the number and arrangement of the electrode units 12 of the electrode sheet 10.

[0050] Figure 2 The electrode sheet 10' shown has 20 electrode units 12 arranged in a 4x5 matrix. Figure 1A transformed embodiment of the electrode sheet 10 shown in FIG. 1, the spatial structure of the electrode sheet 10' is the same as that of the electrode sheet 10, and also comprises a plurality of electrode units 12' arranged in intervals, a plurality of connecting portions 111' between adjacent two electrode units 12', a wiring portion 112' connected with the bridging portion 113', a first cable 13' connected with the wiring portion 112', a first interval D1 formed between the third column of electrode units 12' and the fourth column of electrode units 12', and a second interval D2' formed between adjacent rows of electrode units 12'. The connecting portion 111', the wiring portion 112', and the bridging portion 113' also constitute a flexible circuit board (not labeled), and the electrode sheet 10' is also plugged with the adapter 20 through the first plug 41' of the first cable 13' having 10-core conductive wires. The difference is that the two electrode units 12' in the fourth column are both arranged in a disconnected manner, and are not connected through the longitudinally arranged connecting portion 111', but the two electrode units 12' in the fifth column are connected through the longitudinally arranged connecting portion 111', and each electrode unit 12' in the fourth column is connected with the electrode unit 12' in the fifth column and adjacent in the row direction through the transversely arranged connecting portion 111'. The bridging portion 113' is connected between the two electrode units 12' in the third row and the fourth column. One stem 114' is formed by the electrode units 12' in the third column and the connecting portions 111' between the electrode units 12' in the third column, and the other stem 114' is formed by the electrode units 12' in the fifth column and the connecting portions 111' between the electrode units 12' in the fifth column. The structure of the left part of the left three columns of the electrode array (not labeled) is the same as that of the left part of the electrode array (not labeled) shown in FIG. 1. Figure 1 The structure of the left part of the electrode array (not labeled) shown in FIG. 1 is exactly the same as that of the left part of the electrode array (not labeled) shown in FIG. 2, and only the right part is changed because the position of the stem 114' is changed from the fourth column to the fifth column, so that the branch 115' in the right part is arranged respectively from the left and right sides of the corresponding electrode unit 12' in the stem 114'.

[0051] Figure 3 For Figure 1 the electrode sheet 10 shown in FIG. 1 or Figure 2 the transformed embodiment electrode sheet 10' and the circuit connection schematic diagram of the adapter 20 of the first embodiment. It is worth noting that: Figure 3 the arrangement of the electrode units 12 shown in FIG. 1 is to more clearly show the electrical connection between the electrode sheet 10 and the adapter 20, Figure 3 the arrangement of the electrode units 12 shown in FIG. 1 does not represent the spatial arrangement of the electrode units 12. The following is a circuit connection description taking the electrode sheet 10 in the first embodiment as an example.

[0052] in combination with Figure 1 and Figure 3In the embodiment, 20 electrode units 12 are arranged on each electrode sheet 10, and the 20 electrode units 12 are arranged in four rows and five columns in circuit connection and are grouped in order of 1-20. The temperature sensor 14 of each electrode unit 12 includes a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and the temperature sensor 14 of each electrode unit 12 are welded on the flexible circuit board 11, and the dielectric element 15 is short-circuited with the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in four rows and five columns in circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, the plurality of temperature sensors 14 are arranged in four rows and five columns in circuit connection, and the plurality of dielectric elements 15 are arranged in four rows and five columns in circuit connection. It should be noted that the arrangement mode herein is to more clearly show the electrical connection between the electrode sheet 10 and the adapter 20, and does not represent the spatial structure of the electrode units 12. The spatial structure of the electrode units 12 can be a generally arrayed structure as shown in Figure 1 the drawings, or other structures such as petal-shaped or scattered, which can be regular or irregular structures. The dielectric element 15 is configured to apply an alternating electric field to the tumor site of the patient. The temperature sensor 14 is configured to detect the temperature of the body surface of the patient in contact with the electrode sheet 10 and output a temperature detection signal to the adapter 20.

[0053] The flexible circuit board 11 is embedded with multiple conductive tracks 171, 172, 18, 19, including multiple ground lines 18, multiple dual-purpose signal lines 19, one ground track 171 and one communication line 172. One end of the ground track 171 is connected to the ground pin of the handshake chip 17, and the other end is connected to any one of the ground lines 18. The ground pin of the handshake chip 17 is connected to the ground track 171, and the communication pin is connected to the communication line 172. That is, the handshake chip 17 is grounded through the ground line 18 connected to the ground track 171, and communicates with the external device through the communication line 172. Specifically, the handshake chip 17 is grounded through the ground track 171 connected to the ground pin and the ground line 18, and sequentially communicates with the electric field generator 30 through the communication line 172 of the flexible circuit board 11, a wire connected to the communication line 172 of the flexible circuit board 11, the adapter 20 connected to the first cable 13, and the electric field generator 30 connected to the adapter 20, thereby determining the connection state of the electrode sheet 10. The first cable 13 has multiple core wires (not shown) that are respectively and electrically connected to the communication line 172, the multiple ground lines 18 and the multiple dual-purpose signal lines 19 of the flexible circuit board 11. The total number of the communication line 172, the ground line 18 and the dual-purpose signal line 19 embedded in the flexible circuit board 11 is not more than 10. Therefore, the number of wires of the first cable 13 is not more than 11.

[0054] The number of conductive lines electrically connected to the ground lines 18 in the tumor electric field treatment system 100 is related to the number of row groups M of the electrode unit 12, which can be greater than or equal to the number of row groups of the electrode unit 12, and M is a positive integer. The number of conductive lines electrically connected to the dual-purpose signal lines 19 in the tumor electric field treatment system 100 is related to the number of column groups N of the electrode unit 12, which can be greater than or equal to the number of column groups of the electrode unit 12, and N is a positive integer. In this embodiment, the number of ground lines 18 is equal to the number of row groups M of the electrode unit 12; the number of dual-purpose signal lines 19 is equal to the number of column groups N of the electrode unit 12. The number of lines L embedded in the flexible circuit board 11 is equal to the sum of the number of ground lines 18 and the number of dual-purpose signal lines 19 plus 2, that is, L = M + N + 2. The number of wires of the first cable 13 is M + N + 1.

[0055] The multi-path dual-purpose signal lines 19 of the flexible circuit board 11 are respectively arranged in one-to-one correspondence with the multiple column groups of the electrode units 12, and are configured to transmit the alternating current signal generated by the electric field generator 30 to the dielectric elements 15 in each electrode unit 12 in the corresponding column group. That is, the dielectric elements 15 in the same column group are all short-circuited by the same path dual-purpose signal line 19 of the flexible circuit board 11, and the dielectric elements 15 in different column groups are respectively connected in parallel by different path dual-purpose signal lines 19 of the flexible circuit board 11. The dual-purpose signal lines 19 of the flexible circuit board 11 are respectively electrically connected with the corresponding conductive lines in the first cable 13, and are electrically connected to the electric field generator 30 through the adapter 20. That is, the dual-purpose signal lines 19 of the flexible circuit board 11 receive the alternating current signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.

[0056] The multi-path ground lines 18 are respectively arranged in one-to-one correspondence with the multiple row groups of the electrode units 12, and are respectively used to sequentially short-circuit the temperature sensors 14 of the corresponding electrode units 12 in each row group to ground. That is, the ground ends 14-1 of the multiple temperature sensors 14 in the same row group are all short-circuited by the same path ground line 18 of the flexible circuit board 11, and the ground ends 14-1 of the temperature sensors 14 in different row groups are respectively connected in parallel by different path ground lines 18 of the flexible circuit board 11. In the time period for temperature detection or in the second mode, only one path of the multi-path ground lines 18 is turned on at the same time, and the remaining paths are all disconnected.

[0057] Each of the multipath dual-purpose signal lines 19 is also configured to transmit a direct current signal to the temperature sensor 14 in each electrode unit 12 in the corresponding column group to collect and transmit a detected temperature detection signal. The signal terminals 14-2 of the temperature sensors 14 in different column groups are respectively connected in parallel through different paths of the dual-purpose signal lines 19 of the flexible circuit board 11, and the signal terminals 14-2 of the temperature sensors 14 in the same column group are all short-circuited to the same path of the dual-purpose signal line 19 of the flexible circuit board 11, and the short-circuiting point serves as a temperature sampling point. Specifically, each path of the dual-purpose signal line 19 is configured to short-circuit the signal terminal 14-2 of the temperature sensor 14 of at most one electrode unit 12 in each row group to an external device for receiving a detection signal, wherein the signal terminals 14-2 of the temperature sensors 14 connected by each path of the multipath dual-purpose signal lines 19 are different from each other to avoid subsequent output of repeated signals by the dual-purpose signal line 19. That is, when the number of electrode units 12 in a certain row group is the same as the number of paths of the dual-purpose signal line 19, each path of the dual-purpose signal line 19 is electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different electrode unit 12 in the row group, respectively; when the number of electrode units 12 in a certain row group is less than the number of paths of the dual-purpose signal line 19, there is at least one path of the dual-purpose signal line 19 that is not electrically connected to the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12, and the remaining paths of the dual-purpose signal line 19 are respectively electrically connected to the signal terminals 14-2 of the temperature sensors 14 of different electrode units 12 in the row group. In the embodiment, the external device for receiving the detection signal is the adapter 20. The dual-purpose signal lines 19 of the flexible circuit board 11 receive a direct current signal from the adapter 20 or the electric field generator 30 through the first cable 13, and transmit the collected or detected temperature signal to the adapter 20, which then transmits the temperature signal to the electric field generator 30.

[0058] In the embodiment, in the case where the temperature sensor 14 is configured in each electrode unit 12 for temperature detection, the above-mentioned circuit design is used to reduce the number of conductive wires of the first cable 13, avoid thickening of the cable, hardening of the softness of the cable, and increase the difficulty of cable fixation; at the same time, the increase in the number of conductive wires of the first cable 13 does not affect the adhesion effect between the electrode sheet 10 and the corresponding body surface of the tumor site of the patient.

[0059] The 9 lines embedded in the flexible circuit board 11 include 4 ground lines 18 and 5 dual-purpose signal lines 19. In this embodiment, the 4 ground lines 18 embedded in the flexible circuit board 11 are 4 lines, and the 5 dual-purpose signal lines 19 are 5 lines. Specifically, the electrode sheet 10 of this embodiment includes 4 ground lines 18, each of which is used to ground the ground terminals 14-1 of the temperature sensors 14 in the same row group. The 4 ground lines 18 of the electrode sheet 10 are respectively a first ground line 18-1, a second ground line 18-2, a third ground line 18-3, and a fourth ground line 18-4. In the 4 row groups of the electrode sheet 10, the first row group includes the electrode units 12-1 to 12-5, the second row group includes the electrode units 12-6 to 12-10, the third row group includes the electrode units 12-11 to 12-15, and the fourth row group includes the electrode units 12-16 to 12-20. Specifically, the first ground line 18-1 is used to ground the electrode units 12-1 to 12-5 in the first row group; the second ground line 18-2 is used to ground the electrode units 12-6 to 12-10 in the second row group; the third ground line 18-3 is used to ground the electrode units 12-11 to 12-15 in the third row group; and the fourth ground line 18-4 is used to ground the electrode units 12-16 to 12-20 in the fourth row group. It should be noted that these ground lines 18 can be selectively closed or disconnected, which can be achieved by connecting each ground line 18 in series with a switch, which will be described in detail below. The above-mentioned "grounding the electrode units 12" can refer to grounding the ground terminals 14-1 of the temperature sensors 14 in the electrode units 12, or can refer to connecting the diodes 16 in series with the temperature sensors 14 of the same electrode units 12 and grounding them together. In short, each ground line 18 short-circuits and grounds the ground terminals 14-1 of the temperature sensors 14 of all electrode units 12 in the corresponding row group. The fourth ground line 18-4 is also short-circuited with the ground trace 171 connected to the ground pin of the handshake chip 17.

[0060] With continued reference to Figure 3As shown, the electrode sheet 10 of the present embodiment also includes five two-way signal lines 19, one end of each of the two-way signal lines 19 is connected to all the electrode units 12 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting alternating current signals. That is, for each row group, each of the two-way signal lines 19 can selectively connect one of the electrode units 12 or none of the electrode units 12 in the row group to avoid subsequent output of duplicate signals from the two-way signal lines 19. Specifically, the five two-way signal lines 19 of the electrode sheet 10 include a first two-way signal line 19-1, a second two-way signal line 19-2, a third two-way signal line 19-3, a fourth two-way signal line 19-4, and a fifth two-way signal line 19-5. One end of the first two-way signal line 19-1 is simultaneously connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-1, 12-6, 12-11, and 12-16; one end of the second two-way signal line 19-2 is simultaneously connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-2, 12-7, 12-12, and 12-17; one end of the third two-way signal line 19-3 is simultaneously connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-3, 12-8, 12-13, and 12-18; one end of the fourth two-way signal line 19-4 is simultaneously connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-4, 12-9, 12-14, and 12-19; and one end of the fifth two-way signal line 19-5 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-5, 12-10, 12-15, and 12-20. In short, each of the two-way signal lines 19 parallelly short-circuits the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the electrode units 12 in the same column group and is used to connect to an external device. It should be noted that the two-way signal lines 19 can selectively transmit alternating current signals or receive temperature detection signals, which can be achieved by connecting each of the two-way signal lines 19 in series with a bidirectional switch 26 and cooperating with the closing or opening of the ground line 18, which will be described in detail below.

[0061] In other embodiments, the number of the embedded ground lines 18 and dual-purpose signal lines 19 in the flexible circuit board 11 can be varied according to the circuit arrangement and the number of the electrode units 12 in the electrode sheet 10, which will be described in subsequent embodiments.

[0062] The ground pin of the handshake chip 17 used for confirming the connection state of the electrode sheet 10 in the present embodiment is connected to the fourth ground line 18-4 through the ground trace 171 embedded in the flexible circuit board 11. The first cable 13 has 10-core wires, which are 4 ground lines 18, 5 dual-purpose signal lines 19, and 1 communication line 172. The specific connection relationship and working principle of the handshake chip 17 will be described in detail below.

[0063] The tumor electric field therapy system 100 of the present embodiment includes at least one pair of the above-mentioned electrode sheet 10, an adapter 20 electrically connected to the electrode sheet 10, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheet 10 and the electric field generator 30. In the case where the electric field generator 30 or the adapter 20 controls the ground of the ground pin of the handshake chip 17, the electric field generator 30 sends a handshake communication signal to the handshake chip 17 of the electrode sheet 10 via the communication line 172 of the electrode sheet 10 through the adapter 20, so as to judge the connection state of the electrode sheet 10. In the case where the electrode sheet 10 is connected normally, the electric field generator 30 provides an alternating current signal to the dielectric element 15 in the plurality of electrode units 12 of the electrode sheet 10 via the dual-purpose signal line 19 of the electrode sheet 10 through the adapter 20 or provides a direct current signal to the temperature sensor 14 in the plurality of electrode units 12 of the electrode sheet 10 via the dual-purpose signal line 19 of the electrode sheet 10 through the adapter 20 and receives the temperature detection signal output by the temperature sensor 14 in the plurality of electrode units 12. The adapter 20 is configured to send a handshake communication signal to the communication line 172 of the electrode sheet 10 according to the communication instruction of the electric field generator 30, and is configured to transmit the alternating current signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 10, and is further configured to transmit a direct current signal to the dual-purpose signal line 19 of the electrode sheet 10 and receive the temperature detection signal output by the dual-purpose signal line 19 of the electrode sheet 10.

[0064] Continuing with reference to Figure 3 With Figure 4As shown, the adapter 20 comprises a first controller 22, a plurality of communication transmission lines 211 electrically connected with the first controller 22, a plurality of groups of analog-to-digital converters 23 connected with the first controller 22, a plurality of groups of voltage dividing resistors 24 and a plurality of groups of grounding switches 25 corresponding to the plurality of groups of analog-to-digital converters 23, a plurality of groups of bidirectional switching switches 26 connected with the plurality of groups of analog-to-digital converters 23 one by one, a first communication unit 27, a plurality of AC signal lines 28 connected with each group of bidirectional switching switches 26 one by one, and a first power module 29 connected with the first communication unit 27, the first controller 22 and the plurality of groups of analog-to-digital converters 23 at the same time, which provides direct current power VCC for each electronic component of the adapter 20. The adapter 20 further comprises a plurality of circuit lines (not labeled). The plurality of circuit lines (not labeled) are respectively electrically connected with the plurality of ground lines 18, the plurality of dual-purpose signal lines 19 and the plurality of communication lines 172 in the flexible circuit board 11 of the corresponding electrode sheet 10 through the first cable 13 of the corresponding electrode sheet 10. The plurality of circuit lines (not labeled) comprise a plurality of AC signal lines 28 respectively transmitting AC signals to the corresponding electrode sheet 10 and electrically connected with the plurality of dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheet 10, a plurality of circuit lines (not labeled) respectively electrically connected with the plurality of dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheet 10 and used for supplying power to each temperature sensor 14 of the electrode sheet 10 or transmitting the temperature detection signal of the electrode sheet 10, a plurality of circuit lines (not labeled) respectively electrically connected with the plurality of ground lines 18 in the flexible circuit board 11 of the corresponding electrode sheet 10, and a plurality of communication transmission lines 211 respectively electrically connected with the plurality of communication lines 172 in the flexible circuit board 11 of the corresponding electrode sheet 10. The plurality of communication transmission lines 211 are all connected with the first controller 22. Each communication transmission line 211 is connected with the communication line 172 of the flexible circuit board 11 through the corresponding first connector 40, and the electrical connection between the first controller 22 and the handshake chip 17 can be realized by closing the corresponding grounding switch 25 of the ground pin short-circuiting of the handshake chip 17 of the flexible circuit board 11, so that the handshake chip 17 obtains power supply and opens the data communication function.

[0065] The number P of circuit lines electrically connected with the adapter 20 and the electrode sheet 10 is equal to the sum of the number M of rows and the number N of columns of the electrode unit 12 of the electrode sheet 10 plus 2; the number H of circuits electrically connected with the adapter 20 and X electrode sheets 10 is equal to X times the number of circuit lines electrically connected with a single electrode sheet 10, that is, The number of groups of the grounding switches 25, the number of groups of the bidirectional switching switches 26, the number of the AC lines 28, and the number of the communication transmission lines 211 are all related to the number of the electrode sheets 10. The number of groups of the grounding switches 25, the number of groups of the bidirectional switching switches 26, the number of the AC lines 28, and the number of the communication transmission lines 211 are all the same; and are not less than the number of the electrode sheets 10. Preferably, the number of groups of the grounding switches 25, the number of groups of the bidirectional switching switches 26, the number of the AC lines 28, and the number of the communication transmission lines 211 are all the same as the number of the electrode sheets 10. The following will be described in detail only by taking the electrical connection between one electrode sheet 10 with 20 electrode units 12 and the adapter 20 as an example.

[0066] Each group of the grounding switches 25 is provided with a plurality of grounding switches 25, which are respectively connected to the circuit lines (not labeled) corresponding to the plurality of grounding lines 18 of the corresponding one of the electrode sheets 10 in the adapter 20, and are configured to control the conduction or disconnection of the plurality of grounding lines 18. The circuit lines (not labeled) respectively and one-to-one electrically connecting the plurality of grounding lines 18 of the electrode sheet 10 are grounded at one end close to the grounding switch 25. The number of the grounding switches 25 in each group of the grounding switches 25 is related to the number of the grounding lines 18 of the flexible circuit board 11 of the corresponding electrode sheet 10, and is equal to the number of the grounding lines 18 of the flexible circuit board 11 of the corresponding electrode sheet 10 in the present embodiment. As shown in FIG. 2, the grounding switch 25 is connected to the circuit line (not labeled) corresponding to the grounding line 18 of the electrode sheet 10. Figure 3As shown, in the present embodiment, each group of grounding switches 25 includes a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3, and a fourth grounding switch 25-4. Each group of multiple grounding switches 25 respectively controls the closing or opening of the corresponding ground line 18 of the corresponding electrode sheet 10. Specifically, the first grounding switch 25-1 is used to control the closing or opening of the first ground line 18-1 of the corresponding electrode sheet 10, and in cooperation with the corresponding group of bidirectional switching switches 26, the first grounding switch 25-1 can control the power-on and power-off of the temperature sensors 14 of the five electrode units 12-1 to 12-5 in the first row group of the corresponding electrode sheet 10; the second grounding switch 25-2 is used to control the closing or opening of the second ground line 18-2 of the corresponding electrode sheet 10, and in cooperation with the corresponding group of bidirectional switching switches 26, the second grounding switch 25-2 can control the power-on and power-off of the temperature sensors 14 of the five electrode units 12-6 to 12-10 in the second row group of the corresponding electrode sheet 10; the third grounding switch 25-3 is used to control the closing or opening of the third ground line 18-3 of the corresponding electrode sheet 10, and in cooperation with the corresponding group of bidirectional switching switches 26, the third grounding switch 25-3 can control the power-on and power-off of the temperature sensors 14 of the five electrode units 12-11 to 12-15 in the third row group of the corresponding electrode sheet 10; the fourth grounding switch 25-4 is used to control the closing or opening of the fourth ground line 18-4 of the corresponding electrode sheet 10, and in cooperation with the corresponding group of bidirectional switching switches 26, the fourth grounding switch 25-4 can control the power-on and power-off of the temperature sensors 14 of the five electrode units 12-16 to 12-20 in the fourth row group of the corresponding electrode sheet 10. The above-mentioned grounding switches 25 can be mechanical switches, such as relays. The grounding switches 25 can also be electronic switches, and each grounding switch 25 can be operated by the first controller 22 of the adapter 20.

[0067] In the present embodiment, each group of grounding switches 25 is an electronic switch. The first controller 22 is in communication connection with the multiple groups of grounding switches 25, and is used to control the opening and closing states of the multiple grounding switches 25 in each group of grounding switches 25 in turn and in a cyclic manner, and in turn to individually conduct each ground line 18 in the multiple ground lines 18 of the corresponding electrode sheet 10 and cooperate with the switching of the corresponding bidirectional switching switch 26, so as to sequentially and time-divisionally collect the temperatures of the patient's body surface detected by all the temperature sensors 14 on the electrode sheet 10. The number of each group of grounding switches 25 is greater than or equal to the number of the ground lines 18 of the flexible circuit board 11 of the corresponding electrode sheet 10. In the present embodiment, the number of each group of grounding switches 25 is the same as the number of the ground lines 18 of the corresponding electrode sheet 10.

[0068] Each group of the plurality of bidirectional switches 26 is provided with a plurality of bidirectional switches 26, and the plurality of bidirectional switches 26 in each group are respectively connected into the adapter 20 and are respectively electrically connected to the circuit lines (not labeled) corresponding to the plurality of multipurpose signal lines 19 of the corresponding electrode sheet 10. The number of the bidirectional switches 26 in each group of the bidirectional switches 26 is greater than or equal to the number of the multipurpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10, and is related to the number of the multipurpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10. Figure 3 In the embodiment shown, the number of the bidirectional switches 26 in each group of the bidirectional switches 26 is equal to the number of the multipurpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10. Each bidirectional switch 26 has a sampling end 1 and an input end 2. The sampling ends 1 of the plurality of bidirectional switches 26 in the same group are respectively electrically connected to the corresponding detection channels of the plurality of detection channels of the corresponding group of the analog-to-digital converters 23, and each detection channel corresponds to a corresponding temperature sampling point. The input ends 2 of each bidirectional switch 26 in the same group are electrically connected to the corresponding same AC signal line 28. Each bidirectional switch 26 is configured to control the multipurpose signal line 19 to access the corresponding AC signal line 28 to transmit an alternating current signal or to access the corresponding detection channel of the corresponding group of the analog-to-digital converters 23 to receive a temperature detection signal output by the temperature sensor 14.

[0069] As shown in Figure 3 Taking an example of an electrode sheet 10 being electrically connected to the adapter 20, in the embodiment with 20 electrode units 12, the plurality of bidirectional switches 26 are respectively a first bidirectional switch 26-1, a second bidirectional switch 26-2, a third bidirectional switch 26-3, a fourth bidirectional switch 26-4, and a fifth bidirectional switch 26-5. The plurality of bidirectional switches 26 in the same group respectively control the switching between the transmission of an alternating current signal and the transmission of a temperature detection signal of a corresponding one of the multipurpose signal lines 19 of the same electrode sheet 10.

[0070] Specifically, the first bidirectional switch 26-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode sheet 10 between transmitting the alternating current signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each dielectric element 15 of the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, the electrode unit 12-16 in the first column group of the electrode sheet 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, the electrode unit 12-16 in the first column group, and cooperating with the corresponding first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, the fourth grounding switch 25-4, so that the first column electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, the electrode unit 12-16 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23; the second bidirectional switch 26-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode sheet 10 between transmitting the alternating current signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each dielectric element 15 of the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, the electrode unit 12-17 in the second column group of the electrode sheet 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, the electrode unit 12-17 in the second column group, and cooperating with the corresponding grounding switch 25-1, the grounding switch 25-2, the grounding switch 25-3, the grounding switch 25-4, so that the second column electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, the electrode unit 12-17 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23;The third two-way switch 26-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 10 between transmitting the alternating current signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each dielectric element 15 of the electrode unit 12-3, the electrode unit 12-8, the electrode unit 12-13, the electrode unit 12-18 in the third column group of the electrode sheet 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode unit 12-3, the electrode unit 12-8, the electrode unit 12-13, the electrode unit 12-18 in the third column group, and cooperating with the corresponding first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, the fourth ground switch 25-4, so that the third column electrode unit 12-3, the electrode unit 12-8, the electrode unit 12-13, the electrode unit 12-18 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23; the fourth two-way switch 26-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 10 between transmitting the alternating current signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each dielectric element 15 of the electrode unit 12-4, the electrode unit 12-9, the electrode unit 12-14, the electrode unit 12-19 in the fourth column group of the electrode sheet 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode unit 12-4, the electrode unit 12-9, the electrode unit 12-14, the electrode unit 12-19 in the fourth column group, and cooperating with the corresponding first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, the fourth ground switch 25-4, so that the fourth column electrode unit 12-4, the electrode unit 12-9, the electrode unit 12-14, the electrode unit 12-19 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23;The fifth bidirectional switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode pad 10 between the transmission of the alternating current signal and the transmission of the temperature detection signal, thereby controlling the switching between the conduction of each dielectric element 15 of the electrode units 12-5, 12-10, 12-15, 12-20 in the fifth column group of the electrode pad 10 and the conduction of the signal end 14-2 of each temperature sensor 14 of the electrode units 12-5, 12-10, 12-15, 12-20 in the fifth column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the fifth column of electrode units 12-5, 12-10, 12-15, 12-20 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode units 12 to the corresponding analog-to-digital converter 23.

[0071] When each group of grounding switches 25 is disconnected and the input end 2 of each group of bidirectional switches 26 is turned on and the sampling end 1 is disconnected, the alternating current signal can be transmitted to the dielectric element 15 of each electrode unit 12 of the corresponding electrode pad 10, and when the sampling end 1 of each group of bidirectional switches 26 is turned on and the input end 2 is disconnected, it can cooperate with each grounding switch 25 in the corresponding group to transmit the temperature detection signal collected by the temperature sensor 14 of each electrode unit 12 on the electrode pad 10 in time. The bidirectional switch 26 described above can be a mechanical switch, such as a relay. The bidirectional switch 26 can also be an electronic switch, and the switching of the sampling end 1 and the input end 2 of each bidirectional switch 26 can be controlled by the first controller 22 of the adapter 20.

[0072] In the present embodiment, each group of bidirectional switches 26 is an electronic switch. The first controller 22 is in communication connection with the plurality of groups of bidirectional switches 26, and is used to control the switching of each group of bidirectional switches 26 between the sampling end 1 and the input end 2, and cooperate with the closing or opening of the corresponding grounding switch 25, so as to continuously monitor the temperature of the patient's body surface detected by all the temperature sensors 14 on the electrode pad 10 or transmit the alternating current signal to the patient. In the present embodiment, the plurality of groups of grounding switches 25 and the plurality of groups of bidirectional switches 26 jointly form a switch unit (not numbered).

[0073] In this embodiment, each group of analog-to-digital converters 23 is electrically connected one-to-one to the sampling terminals 1 of multiple bidirectional switching switches 26 in the corresponding group through multiple circuit lines (unlabeled) within the adapter 20, and is configured to receive temperature detection signals transmitted from the multi-purpose signal lines 19 of the corresponding electrode sheet 10, and convert the temperature detection signals from analog signals to digital signals. Each group of analog-to-digital converters 23 includes multiple detection channels A, B, C, D, and E, each detection channel A, B, C, D, and E is used to connect to one corresponding multi-purpose signal line 19 in the multi-purpose signal lines 19 through the corresponding bidirectional switching switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switching switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of electrode units 12 of the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26, and is not less than the number of column groups of electrode units 12 in the corresponding electrode sheet 10. For example... Figure 3 As shown, each group of analog-to-digital converters 23 includes five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 through the sampling terminal 1 of the first bidirectional switch 26-1; the second detection channel B is connected to the second dual-purpose signal line 19-2 through the sampling terminal 1 of the second bidirectional switch 26-2; the third detection channel C is connected to the third dual-purpose signal line 19-3 through the sampling terminal 1 of the third bidirectional switch 26-3; the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through the sampling terminal 1 of the fourth bidirectional switch 26-4; and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 through the sampling terminal 1 of the fifth bidirectional switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, and E is connected to a first power supply module 29 via a corresponding voltage divider resistor 24 in the adapter 20. The first power supply module 29 provides a DC signal.

[0074] In the present embodiment, the first communication unit 27 is configured to acquire the digital signals output by the plurality of sets of analog-to-digital converters 23 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control the voltage or current or power of the alternating current signal provided to the plurality of electrode units 12 of the electrode sheet 10 according to the received digital signals. Exemplarily, when any of the plurality of received digital signals exceeds a preset threshold value, it indicates that the temperature at the human body surface to which the dielectric element 15 corresponding to the at least one temperature sensor 14 in the electrode sheet 10 is attached detected by the at least one temperature sensor 14 exceeds a preset threshold temperature (e.g., 41°C, 42°C, etc.), at which time the voltage or current or power of the alternating current signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode units 12 of the electrode sheet 10 from being too hot when the alternating current signal is applied, thereby causing a cold burn to the skin of the patient. The above-mentioned preset threshold temperature and preset threshold value can be determined according to the safety threshold of the human body. The first communication unit 27 is controlled by the first controller 22 and serially transmits the digital signals converted by the plurality of sets of analog-to-digital converters 23. In the present embodiment, the preset temperature threshold value can be a value within 36°C-45°C.

[0075] One end of each of the plurality of communication transmission lines 211 embedded in the adapter 20 is connected to the first controller 22, and the other end is electrically connected to the communication line 172 electrically connected to the communication pin of the handshake chip 17 of the corresponding electrode sheet 10 through the corresponding conductor of the corresponding first cable 13. The ground pin GND of the adapter 22 is also connected to the ground pin of the handshake chip 17 of the corresponding electrode sheet 10 through the ground line 18 to which the corresponding conductor of the corresponding first cable 13 is connected, the ground trace 171 to which the corresponding conductor of the corresponding first cable 13 is connected, and the ground trace 171 short-circuited to the ground line 18. That is, the first controller 22 controls the closing of the ground switch 25 corresponding to the ground line 18-4 short-circuiting the ground pin of the handshake chip 17 of the electrode sheet 10, sends a handshake communication signal to the communication line 172 of the electrode sheet 17 through the communication transmission line 211, and determines whether the connection between the electrode sheet 10 and the adapter 20 is normal according to whether the first controller 22 can receive feedback from the communication line 172 of the electrode sheet 10.

[0076] Reference Figure 4 and Figure 5 In the present embodiment, the first power supply module 29 is electrically connected to the second power supply module 31 of the electric field generator 30 and is configured to supply power to the first controller 22, the plurality of sets of analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. A first connector 40 is provided between each electrode sheet 10 and the adapter 20, and the first connector 40 is adapted to connect the corresponding electrode sheet 10 to the adapter 20. In combination with Figure 1As shown, the first connector 40 includes a first plug 41 provided at the first cable 13 away from the electrode sheet 10 and a first socket 42 provided on the adapter 20, the first plug 41 and the first socket 42 are press spring connectors, that is, the first connector 40 connects the adapter 20 and the electrode sheet 10 in the form of connectors. Each first cable 13 has 5 wires electrically connected to the bidirectional switch 26-1, 26-2, 26-3, 26-4, 26-5 in the corresponding group of bidirectional switches 26 one by one, 4 wires electrically connected to the ground switch 25-1, 25-2, 25-3, 25-4 in the corresponding group of ground switches 25 one by one, and 1 wire electrically connected to the communication line 172 of the electrode sheet 10 and the communication transmission line 211 of the adapter 20. That is, each first connector 40 is electrically connected to the corresponding group of bidirectional switches 26, the corresponding group of ground switches 25 and the corresponding communication transmission line 211 connected to the first controller 22 of the adapter 20 one by one through 10 wires; and connected to the electric field generator 30 through the corresponding AC signal line 28 of the adapter 20.

[0077] The adapter 20 is provided with a second connector 50 adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 further comprises a second cable 21 connected to the second connector 50. The second connector 50 comprises a second plug 51 provided at the end of the second cable 21 away from the first controller 22 and a second socket 52 provided on the electric field generator 30. The second plug 51 and the second socket 52 are press-type spring connectors, i.e. the second connector 50 connects the adapter 20 to the electric field generator 30 in the form of connectors. Each of the first connectors 40, such as X1, Y1, X2 and Y2, is connected to the second connector 50 through a corresponding AC signal line 28. The first connectors 40, such as X1, Y1, X2 and Y2, are respectively connected to a corresponding set of grounding switches 25, a corresponding set of analog-to-digital converters 23 and a corresponding communication transmission line 211. Each of the first connectors 40 is connected to the second connector 50 and a corresponding set of analog-to-digital converters 23 through a corresponding set of bidirectional switching switches 26. Taking the four electrode sheets 10 as an example, the second cable 21 has eight wires, including four wires 1-4 respectively electrically connected to the corresponding AC signal lines 28 and used for transmitting alternating current signals, one wire 5 electrically connected to the data receiving line RX of the first communication unit 27, one wire 6 electrically connected to the data sending line TX of the first communication unit 27, one wire 7 electrically connected to the VCC power line of the first power module 29, and one wire 8 electrically connected to the GND line of the first power module 29. The second connector 50 is connected to the first communication unit 27 through the data receiving line RX and the data sending line TX. The VCC pin of the second connector 50 is connected to the VCC power line of the first power module 29. The GND pin of the second connector 50 is connected to the GND line of the first power module 29 and grounded. The VCC pin of the second connector 50 is further connected to the corresponding set of voltage dividing resistors 24 and the corresponding set of analog-to-digital converters 23 through the VCC power line of the first power module 29.

[0078] REFERENCE Figure 5The electric field generator 30 comprises a second power module 31, a second controller 32, an AC signal generator 34, a second communication unit 33 and a group of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected with the VCC power line of the second power module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power module 31. The second power module 31 is also connected with and supplies power to the second controller 32 and the AC signal generator 34. The second communication unit 33 is electrically connected with the wire 5 of the second connector 50 through its data receiving line RX and is electrically connected with the wire 6 of the second connector 50 through its data sending line TX, so as to realize the information interaction between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected with the second communication unit 33, the AC signal generator 34 and the group of AC signal switches 35. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in the group of AC signal switches 35 and adjust the relevant parameters of the AC signal applied by the AC signal generator 34 according to the relevant digital signals received by the second communication unit 33 from the adapter 20. The relevant parameters of the AC signal include the voltage, current and power of the AC signal. The AC signal generator 34 is electrically connected with the several wires 1, 2, 3, 4 of the second connector 50 for transmitting the AC signal through the group of AC signal switches 35. The group of AC signal switches 35 comprises a plurality of AC signal switches 35, which are arranged in one-to-one correspondence with the plurality of electrode pieces 10. Each AC signal switch 35 is electrically connected with one wire 1, 2, 3, 4 of the second connector 50 for transmitting the AC signal through an AC signal wire 36 and is electrically connected to the corresponding electrode piece 10 through the corresponding wire 1, 2, 3, 4 of the second connector 50, so as to deliver the AC signal to each electrode piece 10. The AC signal generator 34 is electrically connected with the group of AC signal switches 35 through the group of AC signal wires 36.

[0079] Specifically, the number of the AC signal switches 35 of the electric field generator 30 is related to the number of the electrode sheets 10, and in the present embodiment, the number of the AC signal switches 35 is equal to the number of the electrode sheets 10 and is both 4. The AC signal switches 35 include the first AC signal switch 35-1, the second AC signal switch 35-2, the third AC signal switch 35-3, and the fourth AC signal switch 35-4, which are electrically connected one-to-one with the conductive lines 1 to 4 of the second connector 50, respectively.The first AC signal switch 35-1 has one end electrically connected to the AC signal generator 34 through the first AC signal wire 36 of the electric field generator 30, and the other end electrically connected to the corresponding wire 1 for transmitting the AC signal in the second connector 50 through the first AC signal wire 36-1, and electrically connected to the AC signal wire 28 at the port X1 of the adapter 20 through the wire 1 of the second connector 50, and the AC signal wire 28 at the port X1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 delivers the AC signal to the electrode sheet 10 electrically connected to the port X1 of the adapter 20; the second AC signal switch 35-2 has one end electrically connected to the AC signal generator 34 through the second AC signal wire 36 of the electric field generator 30, and the other end electrically connected to the corresponding wire 2 for transmitting the AC signal in the second connector 50 through the second AC signal wire 36-2, and electrically connected to the AC signal wire 28 at the port Y1 of the adapter 20 through the wire 2 of the second connector 50, and the AC signal wire 28 at the port Y1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 delivers the AC signal to the electrode sheet 10 electrically connected to the port Y1 of the adapter 20; the third AC signal switch 35-3 has one end electrically connected to the AC signal generator 34 through the third AC signal wire 36-3 of the electric field generator 30, and the other end electrically connected to the corresponding wire 3 for transmitting the AC signal in the second connector 50 through the third AC signal wire 36-3, and electrically connected to the AC signal wire 28 at the port X2 of the adapter 20 through the wire 3 of the second connector 50, and the AC signal wire 28 at the port X2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 delivers the AC signal to the electrode sheet 10 electrically connected to the port X2 of the adapter 20; the fourth AC signal switch 35-4 has one end electrically connected to the AC signal generator 34 through the fourth AC signal wire 36-4 of the electric field generator 30, and the other end electrically connected to the corresponding wire 4 for transmitting the AC signal in the second connector 50 through the fourth AC signal wire 36-4, and electrically connected to the AC signal wire 28 at the port Y2 of the adapter 20 through the wire 4 of the second connector 50, and the AC signal wire 28 at the port Y2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 10, so as to control whether the AC signal generator 34 delivers the AC signal to the electrode sheet 10 electrically connected to the port Y1 of the adapter 20.

[0080] The working principle of the handshake chip 17 is described in detail as follows. The handshake chip 17 can store energy when the communication line 172 transmits a high level through an external energy storage element (not shown), and release energy when the communication line 172 transmits a low level, so that the handshake chip 17 obtains sufficient power and works normally. Optionally, the energy storage element is a capacitor, so that the handshake chip 17 only needs an additional core line for communication to work normally. The handshake chip 17 is suitable for handshake communication with external devices such as the electric field generator 30 or the adapter 20 to determine the connection state of each pair of electrode sheets 10. After the handshake chip 17 completes handshake communication with the adapter 20 and / or the electric field generator 30, the state of the combination of the bidirectional switch 26 and the grounding switch 25 can be configured to make the electrode sheet 10 apply an alternating current signal or collect temperature. When the electrode sheet 10 needs to collect or measure temperature, all bidirectional switches 26 on the flexible circuit board 11 of the electrode sheet 10 are located at the sampling end 1, and the electric field generator 30 or the adapter 20 can sequentially close each grounding switch 25, so that the analog temperature signal of the corresponding temperature sensor 14 in each row group is sampled at the same time. The analog temperature signal detected by each temperature sensor 14 can also be converted into a type of electrode sheet 10 that can represent the electrode sheet 10 in the case of passing the test, or can be used to represent whether the electrode sheet 10 has a temperature anomaly.

[0081] Specifically, the first controller 22 of the adapter 20 controls the corresponding ground switch 25 connected with the ground pin of the handshake chip 17 to be closed when receiving the handshake signal sent by the electric field generator 30, so that the handshake chip 17 is powered on and works, and the handshake signal is sent to the handshake chip 17. The handshake chip 17 sends a feedback signal, and the first controller 22 on the adapter 20 sends the feedback signal of the handshake chip 17 to the second controller 32 of the electric field generator 30 through the second connector 50. The second controller 32 judges whether the corresponding first controller 22 and the handshake chip 17 complete the handshake communication according to the feedback signal of the handshake chip 17, and configures the state of each ground switch 25 and each bidirectional switch 26 in the switch unit (not numbered) on the adapter 20 to transmit the alternating current signal to the dielectric element of each electrode unit 12 of the electrode sheet 10 or to measure the temperature through the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 after completing the handshake communication. When the electrode sheet 10 is in the temperature acquisition state, the electric field generator 30 controls each bidirectional switch 26 of the adapter 20 through the second controller 32 to make each bidirectional switch 26 be at the acquisition end 1, and closes each ground switch 25 in turn, so that each detection channel of the corresponding analog-to-digital converter 23 acquires the temperature detection signal of each temperature sensor 14 in a row, and obtains a plurality of AD sampling values by analog-to-digital conversion of a plurality of temperature analog signals. The AD sampling value corresponds to a digital temperature. The first controller 22 can also send a plurality of AD sampling values to the electric field generator 30 through the adapter 20, so that the electric field generator 30 identifies the type of the corresponding electrode sheet 10 according to the plurality of AD sampling values in the case that the electrode sheet 10 is qualified, and / or judges whether the corresponding electrode sheet 10 has temperature abnormity according to the plurality of AD sampling values in the process of transmitting the alternating current signal to the corresponding electrode sheet 10.

[0082] The working principle of the tumor electric field treatment system 100 of the embodiment will be described in detail below with reference to Figures 3 to 5 The working principle of the tumor electric field treatment system 100 of the embodiment will be described in detail below with reference to

[0083] The second controller 32 of the electric field generator 30 controls the ground switch 25-4 corresponding to the fourth ground line 18-4 connected with the handshake chip 17 of the electrode sheet 10 to be in the closed state through the first controller 22 of the adapter 20, and sends a handshake signal to the communication line 172 of the electrode sheet 10 through the first controller 22, and judges the connection state between the electrode sheet 10 and the adapter 20 according to whether the feedback of the handshake chip 17 can be received. If the feedback signal from the electrode sheet 10 can be received by the electric field generator 30, it indicates that the connection between the electrode sheet 10 and the adapter 20 is normal; then the electrode sheet 10 can be applied with the alternating current signal or the temperature detection signal collection through the temperature sensor 14 of the electrode sheet 10. If the feedback signal from the electrode sheet 10 is not received by the electric field generator 30, it indicates that the connection between the electrode sheet 10 and the adapter 20 is abnormal, then the second controller 32 of the electric field generator 30 sends a connection abnormality prompt to remind the operator. After the operator handles it, the second controller 32 continues to control the first controller 22 of the adapter 20 to send a handshake communication signal to the handshake chip 17 of the electrode sheet 10, and repeats the above-mentioned operation of judging the connection state of the electrode sheet 10 until the connection between the electrode sheet 10 and the adapter 20 is normal.

[0084] When the electrode sheet 10 is connected normally and the temperature of each electrode unit 12 of a certain electrode sheet 10 needs to be detected, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the sampling end 1 of each of the plurality of bidirectional switching switches 26 of the group of bidirectional switching switches 26 electrically connected to the electrode sheet 10 to be conductive and the input end 2 to be disconnected, so as to disconnect the alternating current signal applied to the electrode sheet 10; at the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each of the group of grounding switches 25 electrically connected to the electrode sheet 10 to be conductive in sequence and in time sharing manner, at this time, the temperature detection signals collected by each temperature sensor 14 of each electrode unit 12 of each row group of the electrode sheet 10 can be collected in time sharing sequence by the plurality of detection channels A, B, C, D, E of the group of analog-digital converters 23 corresponding to the electrode sheet 10. Each detection channel A, B, C, D, E of each group of analog-digital converters 23 only collects the temperature detection signal of the temperature sensor 14 of the corresponding electrode unit 12 located in the same row group of the electrode sheet 10 at the same time, and the above-mentioned temperature detection signal can be characterized by a voltage value. Only one of the four grounding switches 25 in the group of grounding switches 25 corresponding to the electrode sheet 10 can be conductive at the same time, and the other three are disconnected. The five bidirectional switching switches 26 of the group of bidirectional switching switches 26 corresponding to the group of analog-digital converters 23 are all switched to the sampling end 1 to make each of the two-way signal lines 19 of the electrode sheet 10 electrically connected to the corresponding detection channel A, B, C, D, E of the corresponding analog-digital converter 23 in one-to-one correspondence and conductive, in this way, the group of analog-digital converters 23 can collect the voltage values of all temperature sensors 14 of each electrode unit 12 in the same row group short-circuited by the conductive grounding switch 25.

[0085] Specifically, when the first grounding switch 25-1 is closed, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 are all open, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 are all switched to the sampling end 1, the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group are powered on, the temperature sensors 14 of the electrode units 12-6 to 12-20 in the remaining row groups are powered off, the signal ends 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11, and 12-16 are short-circuited on the first detection channel A of the group of analog-to-digital converters 23, only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-1 is connected to the ground, the ground ends 14-1 of the temperature sensors 14 of the electrode units 12-6, 12-11, and 12-16 are all disconnected from the ground, and the diode 16 in series with the temperature sensor 14 is arranged on each electrode unit 12, so the temperature sensors 14 of the remaining electrode units 12 in the first row do not affect the resistance of the temperature sensor 14 of the electrode unit 12-1, and thus only the temperature sensor 14 of the electrode unit 12-1 effectively works on the first detection channel A of the group of analog-to-digital converters 23, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-1. Similarly, the voltage value collected by the second detection channel B of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-2. The voltage value collected by the third detection channel C of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-3. The voltage value collected by the fourth detection channel D of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-4. The voltage value collected by the fifth detection channel E of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-5.

[0086] When the second grounding switch 25-2 is closed, the first grounding switch 25-1, the third grounding switch 25-3 and the fourth grounding switch 25-4 are all open, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to the sampling end 1, the temperature sensors 14 of the electrode units 12-6 to 12-10 in the second row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-5 and 12-11 to 12-20 in the remaining row groups are powered off. The signal end 14-2 of the temperature sensor 14 of each of the electrode units 12-1, 12-6, 12-11 and 12-16 is short-circuited on the first detection channel A of the group of analog-to-digital converters 23. Since only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-6 is connected to the ground, and the ground ends 14-1 of the temperature sensors 14 of the electrode units 12-1, 12-11 and 12-16 are all disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the second row do not affect the resistance of the temperature sensor 14 of the electrode unit 12-6. Therefore, only the temperature sensor 14 of the electrode unit 12-6 effectively works on the first detection channel A of the group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-6. Similarly, the voltage value collected by the second detection channel B of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-7. The voltage value collected by the third detection channel C of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-8. The voltage value collected by the fourth detection channel D of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-9. The voltage value collected by the fifth detection channel E of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-10.

[0087] When the third grounding switch 25-3 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the fourth grounding switch 25-4 are all open, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to the sampling end 1, the temperature sensors 14 of the electrode units 12-11 to 12-15 in the third row group are powered on, the temperature sensors 14 of the electrode units 12-1 to 12-10 and 12-16 to 12-20 in the other row groups are powered off, the signal ends 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11 and 12-16 on the first detection channel A of the group of analog-to-digital converters 23 are shorted, only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-11 is connected to the ground, the ground ends 14-1 of the temperature sensors 14 of the electrode units 12-1, 12-6 and 12-16 are all disconnected, and the diode 16 in series with the temperature sensor 14 is arranged on each electrode unit 12, so the temperature sensors 14 of the electrode units 12-1, 12-6 and 12-16 in the third row do not affect the resistance of the temperature sensor 14 of the electrode unit 12-11, and thus only the temperature sensor 14 of the electrode unit 12-11 on the first detection channel A of the group of analog-to-digital converters 23 works effectively, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-11. Similarly, the voltage value collected by the second detection channel B of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-12. The voltage value collected by the third detection channel C of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-13. The voltage value collected by the fourth detection channel D of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-14. The voltage value collected by the fifth detection channel E of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-15.

[0088] When the fourth grounding switch 25-4 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 are all opened, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to the sampling end 1, the temperature sensors 14 of the electrode units 12-16 to 12-20 in the fourth row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-15 in the remaining row groups are powered off. The signal end 14-2 of the temperature sensor 14 of each of the electrode units 12-1, 12-6, 12-11 and 12-16 is short-circuited on the first detection channel A of the group of analog-to-digital converters 23. Since only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-16 is connected to the ground, and the ground end 14-1 of the temperature sensor 14 of each of the electrode units 12-1, 12-6 and 12-11 is disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the fourth row do not affect the resistance of the temperature sensor 14 of the electrode unit 12-16. Therefore, only the temperature sensor 14 of the electrode unit 12-16 effectively works on the first detection channel A of the group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-16. Similarly, the voltage value collected by the second detection channel B of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-17. The voltage value collected by the third detection channel C of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-18. The voltage value collected by the fourth detection channel D of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-19. The voltage value collected by the fifth detection channel E of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-20. Thus, the first controller 22 of the switcher 20 or the second controller 32 of the electric field generator 30 can collect the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of an electrode sheet 10 by controlling a group of bidirectional switches 26 and a group of grounding switches 25 connected to the electrode sheet 10. Similarly, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of other electrode sheets 10 can be obtained.

[0089] The first controller 22, the plurality of sets of analog-to-digital converters 23 and the plurality of sets of bidirectional switches 26 can automatically perform operations through pre-programmed program codes, for example, the first controller 22 first controls each of the bidirectional switches 26 in the corresponding set of bidirectional switches 26 to switch to the sampling end 1 so that the sampling end 1 of each of the bidirectional switches 26 is turned on and the input end 2 is turned off, so that each of the dual-purpose signal lines 19 of the corresponding electrode sheet 10 is electrically connected to the corresponding set of analog-to-digital converters 23, then the first ground switch 25-1 in the corresponding set of ground switches 25 is closed, and the second ground switch 25-2, the third ground switch 25-3 and the fourth ground switch 25-4 in the set of ground switches 25 are opened, during which each detection channel A, B, C, D, E of the set of analog-to-digital converters 23 acquires the temperature detection signal of each temperature sensor 14 of each electrode unit 12 in the first row group of the corresponding electrode sheet 10 and converts it into a digital signal and stores it in the additionally provided memory, then after a preset interval, the first controller 22 closes the second ground switch 25-2 in the set of ground switches 25, and opens the first ground switch 25-1, the third ground switch 25-3 and the fourth ground switch 25-4 in the set of ground switches 25, during which each detection channel A, B, C, D, E of the set of analog-to-digital converters 23 acquires the temperature detection signal of each temperature sensor 14 of each electrode unit 12 in the second row group. In this way, each ground switch 25 in the set of ground switches 25 is turned on one by one, and the temperature detection signals of all temperature sensors 14 in each row group of the electrode sheet 10 can be obtained. Similarly, the temperature detection signals of all temperature sensors 14 on at least one pair of electrode sheets 10 can be obtained through such operations.

[0090] The tumor electric field treatment system 100 can realize real-time and comprehensive monitoring of the temperature of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 and the core of the first cable 13 electrically connected to the electrode sheet 10, and then can judge whether the electrode sheet 10 is qualified according to the obtained temperature detection signal; or can judge whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal according to the obtained temperature detection signal, and judge whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14 obtained; or can identify the type of the electrode sheet according to the obtained temperature detection signal in the case that the electrode sheet is qualified; or can judge whether the electrode unit 12 of the electrode sheet 10 is over-temperature according to the obtained temperature detection signal in the case that the electrode sheet is qualified, and then control the alternating electric signal applied to the electrode sheet 10 or the corresponding column electrode unit 12 of the electrode sheet 10 to avoid the occurrence of patient body surface low-temperature scald when the tumor treatment is performed through the electrode sheet 10. In addition, the flexible circuit board 11 of the electrode sheet 10 of the present application is electrically connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of the same electrode unit 12 through the same dual-purpose signal line 19, which not only realizes that the alternating current signal, the direct current signal for temperature signal acquisition and the acquired temperature detection signal can be transmitted through the dual-purpose signal line 19, but also greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) arranged thereon, reduces the wiring difficulty of the flexible circuit board 11, simplifies the manufacturing process, and also reduces the weight of the flexible circuit board 11 and the manufacturing cost. The electrode sheet 10 of the present application can also realize switching between applying alternating current signal for tumor treatment and transmitting direct current signal for temperature acquisition and transmitting acquired temperature detection signal through the combination control of the grounding switch 25 electrically connected to the grounding line 18 and the bidirectional switch 26 electrically connected to the dual-purpose signal line 19.

[0091] When the electrode pad 10 is connected normally and it is required to apply an alternating current signal to the patient through each electrode unit 12 of a certain electrode pad 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each ground switch 25 in the group of ground switches 25 corresponding to the electrode pad 10 to be all turned off, and controls each bidirectional switch 26 in the group of bidirectional switches 26 corresponding to the electrode pad 10 to be all switched to the input end 2, so that the sampling end 1 of each bidirectional switch 26 is all turned off and the input end 2 is all turned on, realizing that each two-way signal line 19 of the electrode pad 10 is electrically connected to the AC signal line 28 of the adapter 20 corresponding to the electrode pad 10, so as to transmit the alternating current signal to each electrode unit 12 of the electrode pad 10.When the temperature detection signal of the temperature sensor 14 of all electrode units 12 of the electrode sheet 10 detected is far below the preset temperature threshold value stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through the second controller 32 to continue generating the alternating current signal with the increasing voltage or current amplitude or the unchanged voltage or current amplitude, and then the alternating current signal is transmitted to the corresponding pair of electrode sheets 10 through the corresponding AC signal line 28 of the adapter 20, so that the pair of electrode sheets 10 continues to apply the alternating current signal; when the temperature detection signal of the temperature sensor 14 of all electrode units 12 of the electrode sheet 10 detected is below but close to the preset temperature threshold value stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the alternating current signal generated by the AC signal generator 34 through the second controller 32, and then reduce the voltage or current of the alternating current signal applied to the pair of electrode sheets 10; when it is detected that the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode sheet 10 is greater than the preset temperature threshold value, the electric field generator 30 controls the AC signal switch 35 electrically connected with the electrode sheet 10 to be disconnected through the second controller 32, so as to stop applying the alternating current signal to the electrode sheet 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all the bidirectional switching switches 26 in the group of bidirectional switching switches 26 electrically connected with the electrode sheet 10 to switch from the input end 2 to the sampling end 1, that is, controls all the bidirectional switching sampling ends 1 of the group of bidirectional switching switches 26 electrically connected with the electrode sheet 10 to be all turned on and the input ends 2 to be all disconnected, so as to stop applying the alternating current signal to the electrode sheet 10; or, when it is detected that the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode sheet 10 is greater than the preset temperature threshold value, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected with the electrode sheet 10 to continue to be turned on, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a bidirectional switching switch 26 electrically connected with the electrode unit 12 of the electrode sheet 10 to switch from the input end 2 to the sampling end 1, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 simultaneously controls the input ends 2 of the remaining bidirectional switching switches 26 electrically connected with the electrode units 12 of the electrode sheet 10 whose temperature detection signals do not exceed the preset temperature threshold value and the electrode units 12 whose temperature detection signals exceed the preset temperature threshold value and are in different columns to continue to be electrically connected, so as to stop applying the alternating current signal to all the electrode units 12 in the column where the electrode unit 12 of the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold value is located, and continue to apply the alternating current signal to the remaining column electrode units 12 of the electrode sheet 10 whose temperature detection signals do not exceed the preset temperature threshold value. Thus, the control method of the alternating current signal regional application based on the temperature detection signal of the tumor electric field treatment system 100 is realized.When an AC signal is applied, all grounding switches 25 are disconnected.

[0092] In this embodiment, the grounding switch 25, which is electrically connected to each of the multiple grounding lines 18 of the electrode plate 10, and the bidirectional switching switch 26, which is electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode plate 10, are both located in the adapter 20. However, in other embodiments, the grounding switch 25, which is electrically connected to the grounding line 18, and the bidirectional switching switch 26, which is electrically connected to the dual-purpose signal line 19, may also be located on the electrode plate 10 or in the electric field generator 30, which will not be elaborated here. In addition, the analog-to-digital converter 23 located in the adapter 20 may also be located in the electric field generator 30 and directly controlled by the second controller 32.

[0093] This application also provides other embodiments of the electrode sheet 10. The main differences between the multiple embodiments are the number of electrode units 12 and / or the circuit distribution of the electrode units 12, which will be described below.

[0094] Figure 6 This is a circuit connection diagram of the tumor electric field therapy system used in the second embodiment of this application, showing the electrode sheet 10D and... Figure 1 The circuit connection diagram of the adapter 20 of the first embodiment shown is illustrated below. The circuit description below uses the electrode plate 10D of the second embodiment as an example. In terms of electrical connection, the electrode plate 10D differs from the electrode plate 10 of the first embodiment in the number of electrode units 12 and the circuit arrangement. The electrode plate 10D in this embodiment has 13 of the aforementioned electrode units 12. In terms of electrical connection, the flexible circuit board 11D of the electrode plate 10D arranges these 13 electrode units 12 in three rows and five columns, with each of the two rows having 5 electrode units 12 and the remaining row having 3 electrode units 12. The flexible circuit board 11D of the electrode plate 10D is embedded with 3 ground lines 18, 5 dual-purpose signal lines 19, 1 ground trace 171 that is simultaneously connected to the ground pin of the handshake chip 17 and any ground line 28, and 1 communication line 172 that is connected to the communication pin of the handshake chip 17. Each grounding line 18 is used to ground the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 is used to short-circuit the dielectric element 15 of each electrode unit 12 in each column group and the signal terminal 14-2 of each temperature sensor 14, for receiving temperature detection signals or transmitting AC signals. One grounding line 18 connected to the grounding trace 171 also grounds the grounding pin of the handshake chip 17.

[0095] The 3-way ground lines 18 of the flexible circuit board 11D are a first ground line 18-1, a second ground line 18-2, and a third ground line 18-3, respectively. In the 3 row groups of the electrode sheet 10D, the first row group includes the electrode units 12-1 to 12-5, the second row group includes the electrode units 12-6 to 12-10, and the third row group includes the electrode units 12-11 to 12-13. Specifically, the first ground line 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group, respectively; the second ground line 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-6 to 12-10 in the second row group, respectively; and the third ground line 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-11 to 12-13 in the third row group, respectively, and is also used to ground the ground pin of the handshake chip 17 through the ground trace 171 connected to the ground pin of the handshake chip 17. In short, each of the 3-way ground lines 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group, and one of the 3-way ground lines 18 also shorts and grounds the ground pin of the handshake chip 17.

[0096] The 5-way dual-purpose signal line 19 of the electrode sheet 10D includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-1, 12-6, and 12-11, respectively; one end of the second dual-purpose signal line 19-2 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-2, 12-7, and 12-12, respectively; one end of the third dual-purpose signal line 19-3 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-3, 12-8, and 12-13, respectively; one end of the fourth dual-purpose signal line 19-4 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the two electrode units 12-4 and 12-9, respectively; and one end of the fifth dual-purpose signal line 19-5 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the two electrode units 12-5 and 12-10, respectively. In short, each of the dual-purpose signal lines 19 connects the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the electrode units 12 in the corresponding column group in parallel and is used to connect to the adapter 20.

[0097] The first ground switch 25-1, the second ground switch 25-2, and the third ground switch 25-3 on the adapter 20 are respectively connected in electrical correspondence with the first ground line 18-1, the second ground line 18-2, and the third ground line 18-3 of the electrode sheet 10D through the first connector 40D, and the fourth ground switch 25-4 is in an idle and disconnected state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 on the adapter 20 are respectively connected in electrical correspondence with the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode sheet 10D through the first connector 40D. The communication transmission line 211 on the adapter 20 is connected in electrical correspondence with the communication line 172 connected to the communication pin of the handshake chip 17 of the electrode sheet 10D.

[0098] The working mode of the tumor electric field treatment system formed by the electrode sheet 10D, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment system 100 described above. The second controller 32 of the electric field generator 30 sends a handshake communication signal to the first controller 22 of the adapter 20, and controls the third ground switch 25-3 connected with the electrode sheet 10 to be closed through the first controller 22 of the adapter 20 or directly, the handshake chip 17 is powered on at this time, at this time, the first controller 22 sends a handshake communication signal to the handshake chip, and confirms that the electrode sheet 10 is connected normally after receiving the feedback signal of the handshake chip 17, and confirms that the electrode sheet 10 is connected abnormally when the feedback signal of the handshake chip 17 is not received. When the electrode sheet 10 is connected normally, the electric field generator 30 or the adapter 20 controls 1) all ground switches 25 to be disconnected and the input end 2 of all bidirectional switches 26 to be turned on, and the sampling end 1 to be disconnected, so that all dual-purpose signal lines 19 and AC signal lines 28 are turned on, at this time, all electrode units 12 of the electrode sheet 10 can be applied with alternating current signals; 2) the sampling end 1 of all bidirectional switches 26 is turned on, the input end 2 is disconnected, and each ground switch 25 is turned on in turn, so that the temperature detection signal of each temperature sensor 14 of each electrode unit 12 of each row group of the electrode sheet 10 can be obtained in turn. Among them, the ground switch 25 in the idle off state does not need to be operated.

[0099] Reference Figure 7 As shown in the figure, it is a circuit connection schematic diagram of the tumor electric field treatment system of the third embodiment of the present application, which shows the electrode sheet 10E of the third embodiment and Figure 1 The adapter 20 shown in the figure. The electrode sheet 10E is provided with 13 electrode units 12 like the electrode sheet 10D in the second embodiment, but the specific circuit arrangement is different. The flexible circuit board 11E of the electrode sheet 10E is also arranged into three rows and five columns on the circuit, but each of the two rows has four electrode units 12, and the remaining one row has five electrode units 12. The flexible circuit board 11E of the electrode sheet 10E is also embedded with 3 ground lines 18, 5 dual-purpose signal lines 19, 1 ground trace 171 connected with the ground pin of the handshake chip 17 and any one ground line 28, and 1 communication line 172 connected with the communication pin of the handshake chip 17. Each ground line 18 is used to ground the ground end 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group, and each dual-purpose signal line 19 is used to short the dielectric element 15 and the signal end 14-2 of each temperature sensor 14 in each column group, respectively, for receiving temperature detection signals or transmitting alternating current signals. The ground line 18 connected with the ground trace 171 also grounds the ground pin of the handshake chip 17.

[0100] The 3-way ground lines 18 of the electrode sheet 10E include a first ground line 18-1, a second ground line 18-2, and a third ground line 18-3. The first row group includes the electrode units 12-1 to 12-4, the second row group includes the electrode units 12-5 to 12-8, and the third row group includes the electrode units 12-9 to 12-13. Specifically, the first ground line 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-4 in the first row group, respectively; the second ground line 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-5 to 12-8 in the second row group, respectively, and the third ground line 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-9 to 12-13 in the third row group, respectively, and to ground the ground pin of the handshake chip 17 via the ground trace 171 connected to the ground pin of the handshake chip 17. In short, each of the ground lines 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group, and one of the ground lines 18 also shorts and grounds the ground pin of the handshake chip 17.

[0101] The 5-way dual-purpose signal lines 19 of the electrode sheet 10E include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the three electrode units 12-1, 12-5, and 12-9, respectively, simultaneously; one end of the second dual-purpose signal line 19-2 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the three electrode units 12-2, 12-6, and 12-10, respectively, simultaneously; one end of the third dual-purpose signal line 19-3 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the three electrode units 12-3, 12-7, and 12-11, respectively, simultaneously; one end of the fourth dual-purpose signal line 19-4 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the three electrode units 12-4, 12-8, and 12-12, respectively, simultaneously; and one end of the fifth dual-purpose signal line 19-5 is connected to the signal terminals 14-2 of the dielectric element 15 and the temperature sensor 14 of the electrode unit 12-13. In short, each of the dual-purpose signal lines 19 shorts and connects the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the electrode units 12 in the corresponding column group in parallel, and is used to connect to the adapter 20.

[0102] The first ground switch 25-1, the second ground switch 25-2 and the third ground switch 25-3 on the adapter 20 are respectively electrically connected with the first ground line 18-1, the second ground line 18-2 and the third ground line 18-3 of the electrode sheet 10E through the first connector 40E, and the fourth ground switch 25-4 is in an idle open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 on the adapter 20 are respectively electrically connected with the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5 of the electrode sheet 10E through the first connector 40E. A communication transmission line 211 on the adapter 20 is electrically connected with the communication line 172 connected with the communication pin of the handshake chip 17 of the electrode sheet 10E.

[0103] The working mode of the tumor electric field treatment system formed by the electrode sheet 10E, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment system 100. After the electric field generator 30 controls the adapter 20 and the handshake chip 17 of the electrode sheet 10E to complete handshake communication and confirms that the electrode sheet 10E is normally connected, when all the ground switches 25 are open and the input end 2 of all the bidirectional switches 26 is on and the sampling end 1 is open, all the dual-purpose signal lines 19 are on and the AC signal line 28 is on, and all the electrode units 12 can apply an alternating current signal. When the sampling end 1 of all the bidirectional switches 26 is on and the input end 2 is open, the temperature detection signal of the temperature sensor 14 of each electrode unit 12 in each row group can be obtained by sequentially turning on each ground switch 25. For the ground switch 25 in the idle open state, no operation is needed.

[0104] Reference Figure 8As shown, the electrode sheet 10F of the fourth embodiment has 13 electrode units 12 as the electrode sheet 10D of the third embodiment, but the specific circuit arrangement is different, and the flexible circuit board 11F of the electrode sheet 10F arranges the 13 electrode units 12 in four rows and four columns on the circuit, in which three rows each have 4 electrode units 12, and the remaining one row has 1 electrode unit 12. The electrode sheet 10F includes 4 ground lines 18, 4 dual-purpose signal lines 19, 1 ground trace 171 connected to the ground pin of the handshake chip 17 and any one of the ground lines 18, and 1 communication line 172 connected to the communication pin of the handshake chip 17. Each ground line 18 is used to ground the ground end 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group, and each dual-purpose signal line 19 is used to short the dielectric element 15 and the signal end 14-2 of each temperature sensor 14 in each column group, for receiving the temperature detection signal or transmitting the alternating current signal. The ground line 18 connected to the ground trace 171 also grounds the ground pin of the handshake chip 17.

[0105] The 4 ground lines 18 of the electrode sheet 10F include a first ground line 18-1, a second ground line 18-2, a third ground line 18-3, and a fourth ground line 18-4. The first row group includes the electrode unit 12-1 to the electrode unit 12-4, the second row group includes the electrode unit 12-5 to the electrode unit 12-8, the third row group includes the electrode unit 12-9 to the electrode unit 12-12, and the fourth row group includes the electrode unit 12-13. Specifically, the first ground line 18-1 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the electrode unit 12-1 to the electrode unit 12-4 in the first row group; the second ground line 18-2 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the electrode unit 12-5 to the electrode unit 12-8 in the second row group; the third ground line 18-3 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the electrode unit 12-9 to the electrode unit 12-12 in the third row group; and the fourth ground line 18-4 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the electrode unit 12-13 in the fourth row group. The fourth ground line 18-4 is also connected to the ground trace 171 connected to the ground pin of the handshake chip 17. In short, each ground line 18 shorts and grounds the ground end 14-1 of the temperature sensor 14 of all the electrode units 12 in each row group, and one of the ground lines 18 also shorts and grounds the ground pin of the handshake chip 17.

[0106] The 4-way dual-purpose signal lines 19 of the electrode sheet 10F include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the four electrode units 12-1, 12-5, 12-9, and 12-13; one end of the second dual-purpose signal line 19-2 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-2, 12-6, and 12-10; one end of the third dual-purpose signal line 19-3 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-3, 12-7, and 12-11; and one end of the fourth dual-purpose signal line 19-4 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-4, 12-8, and 12-12. In short, each of the dual-purpose signal lines 19 connects the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the electrode units 12 in the same column group in parallel and is used to connect to the adapter 20.

[0107] The first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, and the fourth ground switch 25-4 on the adapter 20 are respectively and correspondingly connected to the first ground line 18-1, the second ground line 18-2, the third ground line 18-3, and the fourth ground line 18-4 of the electrode sheet 10F through the first connector 40F. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, and the fourth bidirectional switch 26-4 on the adapter 20 are respectively and correspondingly connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 through the first connector 40F, and the fifth bidirectional switch 26-5 is in an idle and disconnected state. The communication transmission line 211 on the adapter 20 is connected to the communication line 172 connected to the communication pin of the handshake chip 17 of the electrode sheet 10F.

[0108] The working mode of the tumor electric field treatment system formed by the electrode sheet 10F, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment system 100. After the handshake communication is completed through the handshake chip 17 and the first controller 22 of the adapter 20 and it is confirmed that the electrode sheet 10F is connected normally, when all the grounding switches 25 are all turned off and the input end 2 of all the bidirectional switches 26 is turned on, all the dual-purpose signal lines 19 and the AC signal lines 28 are turned on, and all the electrode units 12 are connected to the AC signal; when the sampling end 1 of all the bidirectional switches 26 is turned on, the temperature detection signal of the temperature sensor 14 of each electrode unit 12 in each row group can be obtained in turn by sequentially turning on each grounding switch 25. Among them, no operation is performed on the idle grounding switch 25 and / or the idle bidirectional switch 26.

[0109] Reference Figure 9 As shown in FIG. 9, which is a schematic diagram of the circuit connection between the electrode sheet and the adapter 20 of another embodiment of the tumor electric field treatment system of the present application. The difference between the electrode sheet 10H in this embodiment and the electrode sheet described above is also in the number of electrode units 12 and the arrangement of the electrode units 12 in the circuit connection. The electrode sheet 10H in this embodiment is provided with 9 electrode units 12, and the flexible circuit board 11H of the electrode sheet 10H arranges the 9 electrode units 12 into two rows and five columns in the circuit connection, wherein one row has 5 electrode units 12 and the other row has 4 electrode units 12. The flexible circuit board 11H of the electrode sheet 10H is embedded with 2 ground lines 18, 5 dual-purpose signal lines 19, 1 ground trace 171 connected with the ground pin of the handshake chip 17 and any one of the ground lines 28, and 1 communication line 172 connected with the communication pin of the handshake chip 17. Each ground line 18 is used to ground the ground end 14-1 of the temperature sensor 14 of each electrode unit 12 in the corresponding row group, and one ground line 18 is also used to ground the ground pin of the handshake chip 17. Each dual-purpose signal line 19 is used to short the dielectric element 15 and the signal end 14-2 of the temperature sensor 14 of each electrode unit 12 in each column group, for receiving the temperature detection signal or transmitting the AC signal.

[0110] The 2-way ground lines 18 of the electrode sheet 10H are a first ground line 18-1 and a second ground line 18-2, respectively. In the 2 row groups of the electrode sheet 10H, the first row group includes the electrode units 12-1 to 12-5, and the second row group includes the electrode units 12-6 to 12-9. Specifically, the first ground line 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group, respectively; and the second ground line 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-6 to 12-9 in the second row group, respectively, and simultaneously ground the ground pin of the handshake chip 17 via the ground trace 171 connected to the ground pin of the handshake chip 17. In short, each of the 2-way ground lines 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group, wherein one of the 2-way ground lines 18 also grounds the ground pin of the handshake chip 17.

[0111] The 5-way dual-purpose signal lines 19 of the electrode sheet 10H include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the electrode units 12-1 and 12-6, respectively, simultaneously; one end of the second dual-purpose signal line 19-2 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the electrode units 12-2 and 12-7, respectively, simultaneously; one end of the third dual-purpose signal line 19-3 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the electrode units 12-3 and 12-8, respectively, simultaneously; one end of the fourth dual-purpose signal line 19-4 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the electrode units 12-4 and 12-9, respectively, simultaneously; and one end of the fifth dual-purpose signal line 19-5 is connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensor 14 of the electrode unit 12-5. In short, each of the 5-way dual-purpose signal lines 19 shorts and connects in parallel the signal terminals 14-2 of the dielectric elements 15 and the temperature sensors 14 of the electrode units 12 in the corresponding column group, and is used to connect to the adapter 20.

[0112] The first ground switch 25-1 and the second ground switch 25-2 on the adapter 20 are respectively electrically connected with the first ground line 18-1 and the second ground line 18-2 of the electrode sheet 10H through the first connector 40H, and the third ground switch 25-3 and the fourth ground switch 25-4 are in the idle open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 on the adapter 20 are respectively electrically connected with the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5 through the first connector 40H. The communication transmission line 211 on the adapter 20 is electrically connected with the communication line 172 connected with the communication pin of the handshake chip 17 of the electrode sheet 10H.

[0113] The working mode of the tumor electric field treatment system formed by the electrode sheet 10H, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment system 100. After the electric field generator 30 controls the adapter 20 and the handshake chip 17 of the electrode sheet 10E to complete the handshake communication and confirms that the electrode sheet 10E is normally connected, when all the ground switches 25 are open and the input end 2 of all the bidirectional switches 26 is on and the sampling end 1 is open, all the dual-purpose signal lines 19 are on and the AC signal lines 28 are on, and all the electrode units 12 are connected with the alternating current signal. When the sampling end 1 of all the bidirectional switches 26 is on and the input end 2 is open, the temperature detection signal of the temperature sensor 14 of each electrode unit 12 in each row group can be obtained by sequentially turning on each ground switch 25. For the ground switch 25 in the idle open state, no operation is needed.

[0114] In the foregoing embodiments, the number of the ground switches 25 corresponding to each electrode sheet 10, 10D, 10E, 10F, 10H is fixed at 4, and the number of the bidirectional switches 26 corresponding to each electrode sheet 10, 10D, 10E, 10F, 10H is fixed at 5, which can be applicable to various electrode sheets 10, 10D, 10E, 10F, 10H with different numbers of electrode units 12, but in some cases, the ground switches 25 in idle-off state and / or the bidirectional switches 26 in idle-off state will appear, and the program control will be relatively complex. In order to simplify the control program, specific adapters corresponding to the number of ground lines 18 and the number of dual-purpose signal lines 19 of the electrode sheet can be provided to avoid the ground switches 25 in idle-off state and / or the bidirectional switches 26 in idle-off state, and facilitate program control. That is, in other embodiments, the number of the ground switches 25 in each group of the ground switches 25 provided on the adapter 20 can be set according to the number of row groups in which the electrode units 12 of the corresponding electrode sheet are divided in circuit connection, or according to the number of ground lines 18 on the flexible circuit board of the corresponding electrode sheet; the number of the bidirectional switches 26 in each group of the bidirectional switches 26 provided on the adapter 20 can be set according to the number of column groups in which the electrode units 12 of the corresponding electrode sheet are divided in circuit connection, or according to the number of dual-purpose signal lines 19 on the flexible circuit board of the corresponding electrode sheet. Preferably, the number of the ground switches 25 in each group of the ground switches 25 of the adapter 20 is equal to the number of row groups in which the electrode units 12 of the corresponding electrode sheet are divided in circuit connection, or equal to the number of ground lines 18 on the flexible circuit board of the corresponding electrode sheet; the number of the bidirectional switches 26 in each group of the bidirectional switches 26 provided on the adapter 20 is equal to the number of column groups in which the electrode units 12 of the corresponding electrode sheet are divided in circuit connection, or equal to the number of dual-purpose signal lines 19 on the flexible circuit board of the corresponding electrode sheet

[0115] The application further provides a temperature detection method for the electrode sheet 10 of the tumor electric field treatment system 100, as shown in the figure, the method comprises: Figure 10

[0116] Step S10: performing handshake communication with the handshake chip 17 of the electrode sheet 10 through the adapter 20 to judge the connection state of the corresponding electrode sheet 10.

[0117] Step S20: when the electrode sheet 10 is connected to the adapter 20 normally, configuring the switch states of each ground switch 25 and each bidirectional switch 26 corresponding to the electrode sheet 10 through the adapter 20, so as to sample the temperature signals detected by each temperature sensor 14 in each row group through the corresponding temperature sampling points in turn.

[0118] ​The application further provides an electrode sheet type identification method, which is performed when all temperature sensors of the electrode sheet are normally connected, and in addition to the steps S10 and S20, the method further comprises the following steps:

[0119] Step S30: identifying the type of the corresponding electrode sheet 10 according to the sampled temperature signals detected by all temperature sensors 14 of the corresponding electrode sheet 10.

[0120] The temperature signals detected by all temperature sensors 14 of the corresponding electrode sheet 10 obtained in step S30 are temperature analog signals. Step S30 specifically comprises the following steps:

[0121] Step S301: performing digital-to-analog conversion on all the sampled temperature analog signals to obtain a plurality of AD sampling values;

[0122] Step S302: determining the number of electrode units 12 of the corresponding electrode sheet 10 according to the plurality of AD sampling values;

[0123] Step S303: determining the type of the corresponding electrode sheet 10 according to the number of electrode units 12.

[0124] The application further provides an electrode sheet temperature abnormality judgment method, which is performed in the process of tumor electric field treatment by applying an alternating current signal to each electrode unit of the electrode sheet. In addition to the steps S10 and S20, the method further comprises the following steps:

[0125] Step S40: judging whether the corresponding electrode sheet 10 has temperature abnormality according to the sampled temperature signals detected by all temperature sensors of the corresponding electrode sheet.

[0126] Step S40 specifically comprises the following steps:

[0127] Step S401: comparing all the sampled temperature signals with a preset temperature threshold value;

[0128] Step S402: judging whether the electrode sheet has temperature abnormality according to the comparison result.

[0129] The comparison result in step S402 includes that the temperature signal is less than the preset temperature threshold value and the temperature signal is greater than or equal to the preset temperature threshold value. The judgment of temperature abnormality specifically includes that when there is a temperature signal greater than or equal to the preset temperature threshold value in all the sampled temperature signals, the electrode sheet is determined to have temperature abnormality; and when all the sampled temperature signals are less than the preset temperature threshold value, the electrode sheet is determined to have normal temperature. The preset temperature threshold value is 39-44℃, and is preferably 41℃.

[0130] The application further comprises an alternating electric signal adjusting method, which comprises the following steps in addition to steps S10 and S20: regulating the alternating electric signal applied to the corresponding electrode sheet according to the temperature signals detected by all the temperature sensors of the corresponding electrode sheet.

[0131] Reference Figure 11 As shown in the figure, the application further provides an electric field control method applied to the tumor electric field treatment system 100, which comprises the following steps:

[0132] In step 101, the tumor electric field treatment system 100 is connected.

[0133] Specifically, the four electrode sheets 10 are connected to the adapter 20 respectively, the adapter 20 is connected to the electric field generator 30, and the electric field generator 30 is connected to the appropriate power supply.

[0134] In step 102, it is detected whether the user issues a command to turn on the electric field. If no command to turn on the electric field is detected, step 102 is repeated; if the electric field turning-on command is detected, step 103 is entered.

[0135] In step 103, after the electric field generator 30 of the tumor electric field treatment system 100 sends a handshake signal to the electrode sheet 10 connected to the X1 port through the second connector 50, the adapter 20, and the first connector 40 connected to the X1 port, the first controller 22 of the adapter 20 receives a feedback signal from the electrode sheet 10 of the X1 port through the corresponding communication transmission line 211, and judges whether the handshake is passed. If not, step 105 is entered; if yes, step 106 is entered.

[0136] This judgment step can occur in the adapter 20 or the electric field generator 30. In the present embodiment, the judgment step occurs in the adapter 20. Specifically, when the electrode sheet 10 at the X1 port is connected normally, its handshake chip 17 can receive the handshake request signal of the electric field generator 30 and feed back the handshake state to the first controller 22 of the adapter 20, and the first controller 22 judges that the handshake is successful. On the contrary, when the electrode sheet 10 at the X1 port is connected abnormally, the first controller 22 of the adapter 20 cannot obtain the feedback signal of its handshake chip 17, and then the first controller 22 judges that the handshake fails.

[0137] In step 105, the tumor electric field treatment system 100 issues an alarm due to the handshake failure, and then enters step 101.

[0138] In step 106, after the electric field generator 30 sends the handshake signal to the electrode sheet 10 connected to the X2 port through the second connector 50, the adapter 20, and the first connector 40 connected to the X2 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode sheet 10 of the X2 port through the corresponding communication transmission line 211, and judges whether the handshake is passed. If not, it goes to step 105; if yes, it goes to step 107.

[0139] This judgment step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the judgment step occurs in the adapter 20. Specifically, when the electrode sheet 10 at the X2 port is connected normally, its handshake chip 17 can receive the handshake request signal of the electric field generator 30, and feedback the handshake state to the first controller 22 of the adapter 20, and the first controller 22 judges that the handshake is successful. On the contrary, when the electrode sheet 10 at the X2 port is connected abnormally, the first controller 22 of the adapter 20 cannot get the feedback signal of its handshake chip 17, and the first controller 22 judges that the handshake fails.

[0140] In step 107, after the electric field generator 30 sends the handshake signal to the electrode sheet 10 connected to the Y1 port through the second connector 50, the adapter 20, and the first connector 40 connected to the Y1 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode sheet 10 of the Y1 port through the corresponding communication transmission line 211, and judges whether the handshake is passed. If not, it goes to step 105; if yes, it goes to step 108.

[0141] This judgment step can occur in the adapter 20 or the electric field generator 30. In this embodiment, the judgment step occurs in the adapter 20. Specifically, when the electrode sheet 10 at the Y1 port is connected normally, its handshake chip 17 can receive the handshake request signal of the electric field generator 30, and feedback the handshake state to the first controller 22 of the adapter 20, and the first controller 22 judges that the handshake is successful. On the contrary, when the electrode sheet 10 at the Y1 port is connected abnormally, the first controller 22 of the adapter 20 cannot get the feedback signal of its handshake chip 17, and the first controller 22 judges that the handshake fails.

[0142] In step 108, after the electric field generator 30 sends the handshake signal to the electrode sheet 10 connected to the Y2 port through the second connector 50, the adapter 20, and the first connector 40 connected to the Y2 port, the first controller 22 on the adapter 20 receives the feedback signal from the electrode sheet 10 of the Y2 port through the corresponding communication transmission line 211, and judges whether the handshake is passed. If not, it goes to step 105; if yes, it goes to step 109.

[0143] The judging step can occur in the adapter 20 or in the electric field generator 30, and in this embodiment, the judging step occurs in the adapter 20. Specifically, when the electrode sheet 10 at the Y1 port is connected normally, the handshake chip 17 can receive the handshake request signal of the electric field generator 30 and feed back the handshake state to the first controller 22 of the adapter 20, and the first controller 22 judges that the handshake is successful. Conversely, when the electrode sheet 10 at the Y2 port is connected abnormally, the first controller 22 of the adapter 20 cannot receive the feedback signal of the handshake chip 17, and the first controller 22 judges that the handshake is unsuccessful.

[0144] In the above steps 103, 106, 107, and 108, after receiving the handshake signal of the tumor electric field treatment system 100, the adapter 20 needs to control the corresponding grounding switches 25 and the bidirectional switching switches 26 through the first controller 22, so that only one grounding switch 25 connected with the handshake chip 17 is closed, the remaining grounding switches 24 are all disconnected, and the sampling end 1 of the corresponding bidirectional switching switch 26 is all turned on and the input end 2 is all disconnected, so that the handshake chip 17 is electrically connected with the grounding pin GND of the adapter 20 through the first connector 40, so that the handshake chip 17 can work normally. If the connection between the electric field generator 30 and the adapter 20, the connection between the adapters 20, and the connection between the adapter 20 and the electrode sheet 10 are all normal, the handshake signal sent by the electric field generator 30 can finally reach the handshake chip 17 of the electrode sheet 10, and the handshake state of the handshake chip 17 can be fed back to the electric field generator 30. If at least one of the connections between the electric field generator 30 and the adapter 20, the connections between the adapters 20, and the connections between the adapter 20 and the electrode sheet 10 is abnormal, the handshake chip 17 cannot form a loop due to the disconnection of VCC and GND, resulting in that the adapter 20 and the electric field generator 30 receive the handshake state as a null signal, and the handshake fails.

[0145] In step 109, the electric field generator 30 of the tumor electric field treatment system 100 sets the electric field parameters and enters step 110. The electric field parameters include the frequency, voltage, or current or power amplitude of the alternating electric signal, etc.

[0146] In step 110, the adapter 20 sends a temperature reading request to the first connector 40 of the Y1 port and the first connector 40 of the Y2 port to collect the temperature detection signals of the 40 temperature sensors 14 on the electrode sheet 10 at the Y1 port and the electrode sheet 10 at the Y2 port, and then enters step 111.

[0147] In step 111, the tumor electric field treatment system 100 judges the types of the electrode sheet 10 at the Y1 port and the electrode sheet 10 at the Y2 port by collecting the obtained temperature signals, and then enters step 112.

[0148] The determination of the type of electrode patch 10 at the Y1 port and the type of electrode patch 10 at the Y2 port is specifically determined according to the number of temperature detection signals of the electrode patch 10 at the Y1 port and the temperature detection signals of the electrode patch 10 at the Y2 port collected. The determination process can occur in the adapter 20 or in the electric field generator 30. In the present embodiment, the electrode patch 10 has 20 temperature sensors 14, so there are a total of 40 valid temperature signals.

[0149] In step 112, the tumor electric field therapy system 100 determines whether the temperature signals collected by the adapter 20 are abnormal, and if so, proceeds to step 114. If the temperature signals are all normal, it proceeds to step 113.

[0150] In step 113, the electric field generator 30 applies an alternating current signal to a pair of electrode patches 10 connected to the Y1 and Y2 ports, while stopping the application of alternating current signals to a pair of electrode patches 10 connected to the X1 and X2 ports and proceeds to step 115.

[0151] In step 114, the tumor electric field therapy system 100 alarms due to the presence of abnormal temperature signals of the electrode patch 10 connected to the Y1 port or the electrode patch 10 connected to the Y2 port, and then immediately proceeds to step 120.

[0152] In step 115, the adapter 20 sends temperature reading requests to the first connector 40 of the X1 port and the first connector 40 of the X2 port to collect temperature signals corresponding to all temperature sensors 14 on the electrode patch 10 at the X1 port and the electrode patch 10 at the X2 port, and proceeds to step 116.

[0153] In step 116, the tumor electric field therapy system 100 determines the type of electrode patch 10 at the X1 port and the type of electrode patch 10 at the X2 port according to the temperature signals and proceeds to step 117.

[0154] The determination of the type of electrode patch 10 at the X1 port and the type of electrode patch 10 at the X2 port is determined by determining the number of temperature sensors 14 connected to the electrode patch 10 at the X1 port and the electrode patch 10 at the X2 port. The determination process can occur in the adapter 20 or in the electric field generator 30. In the present embodiment, the electrode patch 10 has 20 temperature sensors 14, so there are a total of 40 valid temperature signals.

[0155] In step 117, the tumor electric field therapy system 100 determines whether the temperature signals collected by the adapter 20 are abnormal, and if so, proceeds to step 114. If the 40 valid temperature signals are all normal, it proceeds to step 118.

[0156] In step 118, the electric field generator 30 applies an alternating electric signal to the pair of electrode pieces 10 connected to the X1, X2 ports, while stopping the application of the alternating electric signal to the pair of electrode pieces 10 connected to the Y1, Y2 ports and entering step 119. The total time of step 113, step 115, step 116, step 117 to step 118 is fixed, and the total time is 1s.

[0157] In step 119, the tumor electric field treatment system 100 performs the subsequent steps according to the detection of whether the user has issued a command to turn off the electric field. If it is detected that the command to turn off the electric field has been received, step 120 is entered; if it is not detected that the command to turn off the electric field has been received, step 121 is entered.

[0158] In step 120, the tumor electric field treatment system 100 turns off the electric field and enters step 101. At this time, the electric field treatment is ended and the next command to turn on the electric field is waiting.

[0159] In step 121, the tumor electric field treatment system 100 determines whether the electric field parameters need to be adjusted according to the current electric field amplitude and the collected temperature signal. If the electric field parameters need to be adjusted, step 109 is entered; if the electric field parameters do not need to be adjusted, steps 110 to 119 are entered for circulation. The total time of step 118, step 119, step 121, step 110, step 111, step 112 to step 113 is fixed, which is 1s in this embodiment. In this way, the tumor electric field treatment system 100 can realize the continuous output of the alternating electric signal alternately between the application of the alternating electric signal in the first direction between the pair of electrode pieces 10 connected to the X1, X2 ports and the application of the alternating electric signal in the second direction between the other pair of electrode pieces 10 connected to the Y1, Y2 ports with a period of 2s. At the same time, the tumor electric field treatment system 100 can realize the time interval between the application of the alternating electric signal to the pair of electrode pieces 10 connected to the X1, X2 ports and the application of the alternating electric signal to the other pair of electrode pieces 10 connected to the Y1, Y2 ports to be reduced to 0s; the time interval between the application of the alternating electric signal to the other pair of electrode pieces 10 connected to the Y1, Y2 ports and the application of the alternating electric signal to the pair of electrode pieces 10 connected to the X1, X2 ports to be reduced to 0s, which prolongs the electric field treatment time under the premise of ensuring the accuracy of temperature collection.

[0160] The present application also provides some temperature detection methods and alternating electric signal application control methods, which are described below with the electrode piece 10 as an example.

[0161] The present application provides an electrode piece temperature detection method, which is applied to the electrode piece 10 or the tumor electric field treatment system 100 described above, and is shown in FIG. 10, which includes the following steps: Figure 12

[0162] ​Step 210: in the case that the electrode sheet is confirmed to be normally connected through the handshake chip, control the bidirectional switch 26 electrically connected with each electrode unit 12 of the electrode sheet 10 to disconnect the alternating current signal applied to the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 and connect the direct current signal applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10;

[0163] Step 220: sequentially turn on the grounding switch 25 electrically connected with the grounding terminal 14-1 of the temperature sensor 14 of each row group electrode unit 12 of the electrode sheet 10 to obtain the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10.

[0164] Step 210 specifically: control the bidirectional switch 26 electrically connected with each electrode unit 12 of the electrode sheet 10 to switch from the end electrically connected with the alternating current signal to the end electrically connected with the direct current signal, that is, control the bidirectional switch 26 electrically connected with the electrode sheet 10 to switch from the input end 2 to the sampling end 1; or

[0165] Control the bidirectional switch 26 electrically connected with each electrode unit 12 of the electrode sheet 10 to switch the dielectric element 15 of each electrode unit 12 of the electrode sheet 10 from the on state to the off state and switch the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10 from the off state to the on state.

[0166] The electrode sheet temperature detection method provided by the application can quickly and accurately obtain the temperature detection signals of all electrode units of the electrode sheet; and can determine whether the temperature sensors of the electrode sheet are faulty, abnormal or the electrode sheet is qualified or needs to be replaced according to the obtained temperature detection signals of all temperature sensors of the electrode sheet; can determine whether each electrode unit of the electrode sheet is overheated and further control the alternating current signal applied to the electrode sheet or each electrode unit of the electrode sheet according to the obtained temperature detection signals of all temperature sensors of the electrode sheet in the case that each temperature sensor of the electrode sheet is normal; and can identify the type of the electrode sheet in the case that the temperature detection signals of each temperature sensor of the electrode sheet are normal.

[0167] Referring to Figure 13 The application also provides an alternating current signal application control method for tumor electric field treatment, which comprises the steps 210 and 220, and further comprises:

[0168] Step 260: in the case that the electrode sheet 10 is determined to be not needed to be replaced, control or adjust the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 according to the obtained temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode sheet 10.

[0169] The controlling or adjusting the AC signal applied to each electrode unit 12 of the electrode sheet 10 in step 260 further comprises:

[0170] Step 261: continuing to apply the AC signal to each electrode unit 12 of the electrode sheet 10 when none of the acquired temperature detection signals of each electrode unit 12 of the electrode sheet 10 exceeds the preset temperature threshold; or

[0171] Step 262: stopping to apply the AC signal to each electrode unit 12 of the electrode sheet 10 when there is a temperature detection signal of the acquired temperature detection signals of all electrode units 12 of the electrode sheet 10 exceeding the preset temperature threshold.

[0172] The stopping to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in step 262 comprises stopping to apply the AC signal to all electrode units 12 of the electrode sheet 10, stopping to apply the AC signal to each electrode unit 12 of the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold, or stopping to apply the AC signal to all electrode units 12 in the column of the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold.

[0173] When stopping to apply the AC signal to each electrode unit 12 of the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold, each electrode unit 12 of the electrode sheet 10 whose temperature detection signal does not exceed the preset temperature threshold continues to be applied with the AC signal.

[0174] When stopping to apply the AC signal to all electrode units 12 in the column of the electrode sheet 10 whose temperature detection signal exceeds the preset temperature threshold, all electrode units 12 of the electrode sheet 10 whose temperature detection signal does not exceed the preset temperature threshold and which are in different columns from the electrode unit 12 whose temperature detection signal exceeds the preset temperature threshold continue to be applied with the AC signal.

[0175] The continuing to apply the AC signal to the electrode sheet 10 in step 261 specifically comprises:

[0176] Step 263: continuing to apply the AC signal to each electrode unit 12 of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 or in a manner of keeping the voltage or current amplitude of the AC signal applied to each electrode unit 12 of the electrode sheet 10 unchanged when the temperature detection signal is far below the preset temperature threshold; or

[0177] Step 264: When the temperature detection signal approaches the preset temperature threshold, continue to apply the alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 unchanged or in a manner that reduces the voltage or current amplitude of the alternating current signal applied to each electrode unit 12 of the electrode sheet 10.

[0178] Referring to FIG. 1, the present application also provides a signal control method for tumor electric field therapy, which is used for the electrode sheet 10 and includes the following steps: Figure 14

[0179] Step 310: Control a set of grounding switches 25 and a set of bidirectional switching switches 26 that are electrically connected to the electrode sheet 10 in combination to apply the alternating current signal to each electrode unit 12 of the electrode sheet 10 and perform step 320.

[0180] Step 320: Control a set of grounding switches 25 and a set of bidirectional switching switches 26 that are electrically connected to the electrode sheet 10 in combination to collect the temperature detection signals of each electrode unit of the electrode sheet 10 in a row and perform step 330.

[0181] Step 330: Determine the control mode of a set of grounding switches 25 and a set of bidirectional switching switches 26 that are electrically connected to the electrode sheet 10 according to the collected temperature detection signals and perform step 340.

[0182] Step 340: Control the working state of each electrode unit 12 of the electrode sheet 10 according to the determined control mode of the grounding switches 25 and the bidirectional switching switches 26.

[0183] The working state of each electrode unit 12 of the electrode sheet 10 in step 340 includes one of stopping applying the alternating current signal and continuing to collect the temperature detection signal and stopping collecting the temperature detection signal and continuing to apply the alternating current signal. Continuing to apply the alternating current signal includes continuing to apply the alternating current signal in a manner that increases the voltage or current amplitude of the currently applied alternating current signal, continuing to apply the alternating current signal in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal unchanged, and continuing to apply the alternating current signal in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal.

[0184] The working state of each electrode unit 12 of the electrode sheet 10 is determined by the temperature detection signal collected thereby. Each electrode unit 12 in each region is cyclically switched between applying the alternating current signal and collecting the temperature detection signal through the combined control of the grounding switches 25 and the bidirectional switching switches 26.

[0185] ​Another electrode sheet temperature detection method for a tumor electric field treatment system is provided in the embodiments of the present application, which will be described below with reference to Figure 15 The temperature detection method includes the following steps for the electrode sheet 10 as an example, as shown in FIG. 5.

[0186] Step 510: disconnect the input of the alternating current signal of the electrode sheet 10, and perform combined control on the multiple grounding switches 25 and the multiple bidirectional switching switches 26, and obtain the temperature detection signal of the temperature sensor 14 of the electrode sheet 10 corresponding to each combination.

[0187] Step 520: sample and convert the temperature detection signal detected by each temperature sensor 14 in the electrode sheet 10 to obtain a digital temperature signal.

[0188] Step 530: transmit the digital temperature signal to the electric field generator 30 of the tumor electric field treatment system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 12 according to the digital temperature signal.

[0189] In step 510, the combined control on the multiple grounding switches 25 and the multiple bidirectional switching switches 26 specifically includes the following steps.

[0190] Step 511: place all the bidirectional switching switches 26 in the sampling end 1, so as to turn on the electrical connection between the signal end 14-2 of each temperature sensor 14 of all the electrode units 12 and the corresponding analog-to-digital converter 23.

[0191] Step 512: sequentially and separately close one of the multiple grounding switches 25 in time division manner, so as to sequentially and separately collect the temperature detection signal detected by the temperature sensor 14 of each electrode unit 12 in the corresponding row group.

[0192] In step 512, sequentially and separately closing one of the multiple grounding switches 25 in time division manner can make the detection channel of the analog-to-digital converter 23 and each temperature sensor 14 in the row group corresponding to the closed grounding switch 25 be electrically connected.

[0193] In this way, the temperature detection signal of each temperature sensor 14 in each row group can be sequentially obtained, and then the corresponding temperature of all the electrode units 12 on the electrode sheet 10 can be obtained through the adapter 20 or the electric field generator 30, so that the temperature detection on the surface of the patient is more comprehensive and accurate.

[0194] The tumor electric field therapy system 100 according to the embodiments of the present application can also detect the temperature of a single electrode unit 12 as needed. The method for detecting the temperature of a certain electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the alternating current signal, set the double-way switch 26 corresponding to the column group in which the electrode unit 12 to be separately measured to the sampling end 1, set the remaining double-way switches 26 to the input end 2; at the same time, turn on and ground the ground switch 25 corresponding to the row group in which the electrode unit 12 to be separately measured, and disconnect all the remaining ground switches 25. In this way, the temperature detection signal of the temperature sensor 14 in the electrode unit 12 to be separately measured can be sampled to obtain the temperature of the electrode unit 12. For example, the electrode unit 12 to be separately measured is the electrode unit 12-1, at this time, the first double-way switch 26-1 corresponding to the electrode unit 12-1 is set to the sampling end 1, and the remaining double-way switches (the second double-way switch 26-2, the third double-way switch 26-3, and the fourth double-way switch 26-4) are all set to the input end 2; at the same time, the first ground switch 25-1 corresponding to the electrode unit 12-1 is closed and grounded, and the remaining ground switches (the second ground switch 25-2, the third ground switch 25-3, and the fourth ground switch 25-4) are all disconnected. In this way, the temperature of the electrode unit 12-1 can be detected.

[0195] The embodiments of the present application also provide another method for applying an alternating current signal for tumor electric field therapy, which is applied to the tumor electric field therapy system described above, so as to Figure 1 The tumor electric field therapy system 100 in the above embodiment is taken as an example for description. Please refer to FIG. 10, which shows the method for applying an alternating current signal, which comprises the following steps: Figure 16

[0196] Step 610: Determine the area in which the electrode unit 12 to which the alternating current signal needs to be applied is located in the electrode sheet 10;

[0197] Step 611: Control the multiple ground switches 25 and the multiple double-way switches 26 electrically connected to the electrode sheet 10 in combination to apply the alternating current signal.

[0198] In step 611, the "controlling the multiple ground switches 25 and the multiple double-way switches 26 electrically connected to the electrode sheet 10 in combination" is specifically as follows:

[0199] Step 612: Disconnect all the ground switches 25 electrically connected to the electrode sheet 10;

[0200] Step 613: Determine the column group in which the electrode unit 12 to which the alternating current signal needs to be applied is located according to the area in which the electrode unit 12 to which the alternating current signal needs to be applied is located;

[0201] ​Step 614: determining the column group in which the electrode unit 12 requiring the application of the AC signal is located according to the determination result, and determining the bi-directional switch 26 electrically connected to the electrode unit 12 in the column group;

[0202] In step 610, each 4 electrode units 12 in the electrode sheet 10 are divided into a region, and the 4 electrode units 12 in each region correspond to a column group and are connected to a two-purpose signal line 19 of the same bi-directional switch 26. In other embodiments, the electrode units 12 have other division manners, which are not described herein.

[0203] In step 615, the bi-directional switch 26 electrically connected to the electrode unit 12 requiring the application of the AC signal is controlled to electrically connect the electrode unit 12 requiring the application of the AC signal to the AC signal line 28 to apply the AC signal, and the remaining bi-directional switches 26 are controlled to disconnect the electrical connection between the electrode units 12 in the region not requiring the application of the AC signal and the AC signal line 28 to stop the application of the AC signal.

[0204] In step 615, the bi-directional switch 26 electrically connected to the electrode unit 12 requiring the application of the AC signal is controlled to electrically connect the electrode unit 12 requiring the application of the AC signal to the AC signal line 28 to apply the AC signal, and the remaining bi-directional switches 26 are controlled to disconnect the electrical connection between the electrode units 12 in the region not requiring the application of the AC signal and the AC signal line 28 to stop the application of the AC signal.

[0205] The above methods are applied to the electrode sheets 10D, 10E, 10F and 10H in other embodiments. Since the adapter 20 has the ground switch 25 in the idle and disconnected state and / or the bi-directional switch 26 in the idle and disconnected state not electrically connected to the corresponding electrode sheet 10D, 10E, 10F and 10H, the corresponding ground switch 25 in the idle and disconnected state and / or the bi-directional switch 26 in the idle and disconnected state do not need to be controlled.

[0206] Although each operation is depicted in the drawings as occurring in a particular order, this should not be understood as requiring that the operations must occur in the particular order shown or in sequential order, nor that all of the shown operations must be performed to achieve the desired results.

[0207] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than limit them. Although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that the technical solutions recorded in the foregoing embodiments can be modified, or some or all of the technical features can be replaced equivalently. Such modifications or replacements do not change the essence of the corresponding technical solutions, which should be covered in the scope of the present application. In particular, the technical features mentioned in each embodiment can be combined in any manner as long as there is no structural conflict. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A tumor electric field treatment system, comprising: The system comprises: an electrode sheet comprising a flexible circuit board and a plurality of electrode units and a handshake chip disposed on the flexible circuit board, the electrode unit comprising a dielectric element and a temperature sensor having a signal terminal and a ground terminal, the flexible circuit board being provided with a plurality of ground lines connected to the ground terminals and a plurality of dual-purpose signal lines connected to the signal terminals, and the dielectric element and the signal terminal of the temperature sensor being short-circuited, a plurality of the electrode units being arranged in at least two rows and two columns in circuit, the ground terminals of the temperature sensors in the same row group being short-circuited through the same ground line, and the ground terminals of the temperature sensors in different row groups being connected in parallel through different ground lines respectively; the signal terminals of the temperature sensors in the same column group being short-circuited through the same dual-purpose signal line, and the signal terminals of the temperature sensors in different column groups being connected in parallel through different dual-purpose signal lines respectively; each of the dual-purpose signal lines is configured to transmit an alternating current signal to the dielectric elements of the electrode units in the corresponding column group in a first mode, and transmit a direct current signal to the signal terminals of the temperature sensors of the electrode units in the corresponding column group or transmit a temperature signal detected by the temperature sensors of the electrode units in the corresponding column group in a second mode; and a controller configured to communicate with the handshake chip to determine the connection state of the electrode sheet, and configured to combine the states of the ground lines and the dual-purpose signal lines of the electrode sheet to switch the dual-purpose signal lines between transmitting alternating current signals and temperature detection signals in the case of normal connection of the electrode sheet.

2. The tumor electric field therapy system of claim 1, wherein, The controller is configured to send a handshake signal to the handshake chip and determine whether the electrode sheet is normally connected according to whether feedback from the handshake chip is received.

3. The tumor electric field treatment system of claim 1, wherein, The controller is further configured to control or adjust the alternating current signal transmitted to the dual-purpose signal line according to the temperature detection signals of the electrode units detected.

4. The tumor electric field treatment system of claim 1, wherein, The controller is further configured to determine the working state of each of the electrode units according to the temperature detection signals of the electrode units detected, the working state comprising continuing to apply an alternating current signal or stopping applying an alternating current signal.

5. The tumor electric field treatment system of any one of claims 1-4, wherein, The system has a preset temperature threshold.

6. The tumor electric field therapy system of claim 5, wherein, The controller is further configured to: compare the temperature detection signals of the electrode units obtained with the preset temperature threshold; and control or adjust the alternating current signal transmitted to the dual-purpose signal line according to the comparison result.

7. The tumor electric field treatment system of claim 6, wherein, The controller is configured to: continue to apply an alternating current signal to each of the electrode units of the electrode sheet when the temperature detection signals of each of the electrode units of the electrode sheet obtained do not exceed the preset temperature threshold; or stop applying an alternating current signal to the electrode units of the electrode sheet when there is a temperature detection signal of each of the electrode units of the electrode sheet obtained that exceeds the preset temperature threshold. ​ 8. The tumor electric field treatment system of claim 6, wherein, The comparison result includes not exceeding the preset temperature threshold and exceeding the preset temperature threshold, the not exceeding the preset temperature threshold includes far below the preset temperature threshold and close to the preset temperature threshold, when the temperature detection signal of each electrode unit does not exceed the preset temperature threshold, the controller is further configured to continue transmitting the alternating current signal to the dual-purpose signal line in the following manner: When the temperature detection signal is far below the preset temperature threshold, continue transmitting the alternating current signal to the dual-purpose signal line in the manner of increasing the voltage or current or power amplitude of the alternating current signal currently transmitted to the dual-purpose signal line or keeping the voltage or current, power amplitude of the alternating current signal currently transmitted to the dual-purpose signal line unchanged; Or When the temperature detection signal is close to the preset temperature threshold, continue transmitting the alternating current signal to the dual-purpose signal line in the manner of keeping the voltage or current or power amplitude of the alternating current signal currently transmitted to the dual-purpose signal line unchanged or decreasing the voltage or current or power amplitude of the alternating current signal currently transmitted to the dual-purpose signal line.

9. The tumor electric field treatment system of claim 1, wherein, The controller is further configured to: determine the type of the electrode sheet according to the temperature detection signal of each electrode unit; or determine whether the electrode sheet has temperature abnormality according to the temperature detection signal of each electrode unit; Or determine whether the temperature sensor of the electrode sheet has failure according to the temperature detection signal of each electrode unit; Or determine whether the electrode unit of the electrode sheet has over-temperature according to the temperature detection signal of each electrode unit.

10. The tumor electric field treatment system of claim 9, wherein, The controller is further configured to determine whether the electrode sheet needs to be replaced according to the failure condition of the temperature sensor of the electrode sheet.

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