A sheep colostrum and polypeptide and a method for preparing the same.

By preparing the polypeptide AEDVGDVAFVKNDT and adding it to sheep colostrum, and then fermenting it with Lactobacillus rhamnosus, the problem of RSV infection resistance was solved, and the antiviral and repair-promoting functions of sheep colostrum were realized. This method is suitable for the preparation of food and medicine.

CN121652236BActive Publication Date: 2026-05-26HUNAN NUTRITION TREE BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HUNAN NUTRITION TREE BIOTECHNOLOGY CO LTD
Filing Date
2026-02-05
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

There is a lack of effective methods to combat human respiratory syncytial virus (RSV) infection in the current technology, especially for infants and the elderly, and there are no specific drugs or vaccines available.

Method used

By preparing a polypeptide AEDVGDVAFVKNDT and adding it to sheep colostrum, followed by fermentation with Lactobacillus rhamnosus UP180 and then specific sterilization, homogenization, concentration and freeze-drying steps, sheep colostrum with antiviral and repair-promoting functions was prepared.

Benefits of technology

The peptides in this sheep colostrum can inhibit the fusion of RSV surface protein F with the host cell membrane, effectively resist RSV infection, promote respiratory mucosal repair, and are suitable for the preparation of food and medicine.

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Abstract

This invention provides a polypeptide with the sequence AEDVGDVAFVKNDT. The polypeptide provided by this invention can inhibit human respiratory syncytial virus (RSV) surface protein F, thereby inhibiting its fusion with the host cell membrane. This invention also provides sheep colostrum. The sheep colostrum includes the aforementioned polypeptide with antiviral function; therefore, this sheep colostrum helps elderly people with weakened immune systems resist RSV infection and promotes the repair of respiratory mucosa. This invention also provides a method for preparing sheep colostrum. This preparation method is simple and can be industrially produced. This invention also provides a method for preparing the aforementioned polypeptide.
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