Tablet-shaped skin cleanser

Abstract

The present invention addresses the problem of providing a novel bubble-free tablet-like skin cleanser. As a solution, the present invention provides a tablet-like skin cleanser characterized by containing (A) to (C): (A) rod-like crystalline cellulose, (B) an anionic surfactant, and (C) at least one of acrylic ester crosslinkable polymer-2-sodium and sodium carboxymethyl starch.

Description

Technical Field

[0001] This invention relates to a tablet-shaped skin cleanser. Background Technology

[0002] Skin cleansing agents in tablet form (hereinafter also referred to as tablet cleansing agents) are known to be formed by compressing powder. Tablet cleansing agents aim to disintegrate rapidly upon contact with water and exhibit excellent usability, such as rapid foaming or foam production. To improve the disintegration properties of tablet cleansing agents, for example, Patent Documents 1 and 2 propose the formulation of carbonates and acids as foaming components, Patent Document 3 proposes setting the pore size to a large porosity of 15% or more, and Patent Document 4 proposes the formulation of croscarmellose sodium as a disintegrant.

[0003] In recent years, non-foaming skin cleansers have attracted attention as skin cleansers. However, the inventors have found that there are currently no non-foaming tablet-type skin cleansers on the market.

[0004] Patent documents Patent Document 1: Japanese Patent Application Publication No. 62-030197 Patent Document 2: Japanese Patent Application Publication No. 5-247495 Patent Document 3: Japanese Patent Application Publication No. 10-183198 Patent Document 4: Japanese Patent Application Publication No. 2007-126574 Summary of the Invention The objective of this invention is to provide a novel non-foaming tablet-shaped skin cleanser.

[0005] The method for solving the problem of the present invention is as follows.

[0006] 1. A tablet-shaped skin cleanser, characterized in that it contains (A) to (C): (A) Rod-shaped crystalline cellulose, (B) Anionic surfactants, (C) Sodium 2-acrylate cross-linked polymer and sodium carboxymethyl starch.

[0007] 2. The tablet-shaped skin cleanser according to 1, characterized in that it contains (D) other crystalline cellulose.

[0008] 3. The tablet-shaped skin cleanser according to 1 or 2, characterized in that the total crystalline cellulose (A+D) accounts for more than 45% by mass relative to the whole.

[0009] 4. The tablet-shaped skin cleanser according to any one of 1. to 3, characterized in that the ratio of (A) rod-shaped crystalline cellulose to total crystalline cellulose (A+D) (A / (A+D)) is 15% by mass or more.

[0010] 5. The tablet-shaped skin cleanser according to any one of 1. to 4, characterized in that (C) is in a proportion of 0.5% by mass or more and 15% by mass or less relative to the whole.

[0011] According to the present invention, a non-foaming tablet-shaped skin cleanser, which is an unprecedented novel skin cleanser, is provided. The tablet-shaped skin cleanser of the present invention not only has excellent formability and disintegration properties, but also forms a smooth paste with excellent thickness and spreadability.

[0012] Because the skin cleanser of the present invention is in tablet form and contains no water, it can be manufactured without preservatives. Because the skin cleanser of the present invention is in tablet form, it is easy to carry and store. The manufacturing process of the skin cleanser of the present invention uses a small amount of water, which also has potential from the perspective of water resource conservation. Detailed Implementation

[0013] The tablet-shaped skin cleanser of the present invention contains one or more of (A) rod-shaped crystalline cellulose, (B) anionic surfactant, (C) sodium 2-acrylate crosslinker, and sodium carboxymethyl starch. Because it contains these components (A), (B), and (C), the tablet-shaped skin cleanser of the present invention exhibits excellent formability and disintegration properties, and when water is added, it yields a high-quality paste with excellent application feel.

[0014] (A) Rod-shaped crystalline cellulose The tablet-shaped skin cleanser of the present invention contains (A) rod-shaped crystalline cellulose. Furthermore, in this specification, rod-shaped crystalline cellulose refers to crystalline cellulose with an aspect ratio (major diameter / minor diameter) of 3 or more. By containing rod-shaped crystalline cellulose with an aspect ratio (major diameter / minor diameter) of 3 or more, the tablet-shaped skin cleanser of the present invention can form a smooth paste with excellent thickness and extensibility. In the present invention, the aspect ratio of the rod-shaped crystalline cellulose is preferably 3.2 or more, more preferably 3.5 or more, further preferably 4.0 or more, and even more preferably 4.2 or more.

[0015] The particle size of the rod-shaped crystalline cellulose is preferably 30 μm or more and 80 μm or less. When the particle size is less than 30 μm, the thickness of the paste may be reduced, while when it exceeds 80 μm, a rough texture may sometimes occur. The particle size of the rod-shaped crystalline cellulose is more preferably 35 μm or more, further preferably 40 μm or more, and even more preferably 70 μm or less, and even more preferably 60 μm or less.

[0016] Furthermore, the aspect ratio is generally determined by electron microscopy observation of the powder, while the particle size is a value obtained based on sieving tests, electron microscopy observation, and particle size distribution determination by laser diffraction / scattering methods. In this invention, the aspect ratio (major axis / minor axis) of crystalline cellulose is the average value calculated by observing more than 1000 crystalline cellulose particles using an electron microscope. For particles with an area ranging from 100 to 200 particles, the length of the longest axis from end to end (major axis) is taken as the major axis, and the length of the particle in the direction perpendicular to the major axis at the center is taken as the minor axis. In addition, the particle size is a value calculated as a cumulative 50% by weight in sieving tests (Japanese Industrial Standard JIS Z 8815).

[0017] The angle of repose of the rod-shaped crystalline cellulose is preferably 46 degrees or higher. Developing rod-shaped crystalline cellulose with an angle of repose of 46 degrees or higher tends to increase the thickness of the paste. More preferably, the angle of repose of the rod-shaped crystalline cellulose is 47 degrees or higher, even more preferably 48 degrees or higher, and still more preferably 49 degrees or higher.

[0018] The water absorption of rod-shaped crystalline cellulose is preferably 200% (w / w) or higher. Rod-shaped crystalline cellulose with a water absorption of 200% or higher has good hydrophilicity, thus easily yielding a smooth paste. More preferably, the water absorption of rod-shaped crystalline cellulose is 210% (w / w) or higher, and even more preferably 220% (w / w) or higher. In this invention, the water absorption is a value calculated based on the oil absorption test method of pigment testing (Japanese Industrial Standard JIS K 5101-13).

[0019] As rod-shaped crystalline cellulose, rod-shaped crystalline cellulose used as a pharmaceutical additive or food additive can be used without any restrictions. For example, commercially available products such as "CEOLUS ST-02," "CEOLUS ST-100," and "CEOLUS OD-20F" sold by Asahi Kasei Corporation, "VIVAPUR CS20 FM" sold by Rettenmaier Japan, and "Comprecel 101" sold by Fushimi Pharmaceutical Co., Ltd. can be used. In addition, rod-shaped crystalline cellulose can be used in combination with one or more rod-shaped crystalline celluloses with different aspect ratios, particle sizes, angles of repose, and water absorption.

[0020] (D) Other crystalline cellulose The tablet-shaped skin cleanser of the present invention may contain other crystalline cellulose with an aspect ratio of less than 3 (D).

[0021] In the present invention, when the tablet-shaped skin cleanser contains (D) other crystalline cellulose, the ratio of (A) rod-shaped crystalline cellulose to total crystalline cellulose (A+D) (A / (A+D)) is preferably 15% by mass or more. When the ratio of (A) rod-shaped crystalline cellulose to total crystalline cellulose is less than 15% by mass, the good creamy texture resulting from the formulation based on (A) rod-shaped crystalline cellulose may sometimes be reduced. The ratio of (A) rod-shaped crystalline cellulose to total crystalline cellulose is more preferably 20% by mass or more, further preferably 30% by mass or more, even more preferably 40% by mass or more, even more preferably 50% by mass or more, even more preferably 60% by mass or more, even more preferably 70% by mass or more, even more preferably 80% by mass or more, even more preferably 90% by mass or more, even more preferably 95% by mass or more, even more preferably 98% by mass or more, and even more preferably 99% by mass or more.

[0022] The proportion of total crystalline cellulose (A+D, where (D) is arbitrary) in the tablet-shaped skin cleanser of the present invention is not particularly limited, but is preferably 45% by mass or more relative to the whole. When the proportion of total crystalline cellulose is less than 45% by mass, the formability may sometimes decrease. The proportion of total crystalline cellulose relative to the whole is more preferably 50% by mass or more, further preferably 60% by mass or more, and even more preferably 70% by mass or more. In addition, the upper limit of the proportion of total crystalline cellulose relative to the whole is not particularly limited as long as the effect of the present invention can be achieved, for example, it can be set to 95% by mass or less, 90% by mass or less, 85% by mass or less, etc.

[0023] (B) Anionic surfactants Examples of anionic surfactants include higher fatty acid salts, N-acylglycine salts, N-acylglutamate salts, N-acylalanine salts, N-acylhydroxyethanesulfonate, N-acylmethyltaurate, monoalkyl phosphates, ether carboxylates, alkyl sulfonates, and sulfosuccinates.

[0024] Examples of acyl groups in the aforementioned N-acyl anionic surfactants include: octanoyl, decanoyl, lauroyl, myristoyl, palmitoyl, stearoyl, oleoyl, and linoleoyl. Acyl groups can also originate from mixed fatty acids; specific examples include coconut oil fatty acid acyl (cocoyl), palm oil fatty acid acyl, palm kernel oil fatty acid acyl, and tallow fatty acid acyl. As salts, examples include alkali metal salts such as sodium and potassium, alkanolamine salts such as triethanolamine, and basic amino acid salts such as lysine and arginine.

[0025] One type of anionic surfactant can be used, or two or more different anionic surfactants can be used in combination.

[0026] The content of component (B) in the tablet-shaped skin cleanser of the present invention is not particularly limited, but is preferably 0.5% by mass or more and 20% by mass or less relative to the whole. When the content of component (B) is less than 0.5% by mass, the cleansing power may be insufficient, and when it exceeds 20% by mass, it may be difficult to obtain a good paste. The proportion of component (B) relative to the whole is more preferably 1% by mass or more, further preferably 2% by mass or more, even more preferably 15% by mass or less, further preferably 10% by mass or less, and even more preferably 5% by mass or less.

[0027] Other surfactants In addition to (B) anionic surfactants, the tablet-shaped skin cleanser of the present invention can also be formulated with other surfactants such as amphoteric surfactants, cationic surfactants, and nonionic surfactants.

[0028] When the tablet-shaped skin cleanser of the present invention contains other surfactants, it is preferable to contain 50% by mass or more of an anionic surfactant relative to the total surfactant. When the amount of anionic surfactant (B) is less than 50% by mass, usability may sometimes decrease. The proportion of anionic surfactant (B) relative to the total surfactant is more preferably 60% by mass or more, further preferably 70% by mass or more, even more preferably 80% by mass or more, even more preferably 90% by mass or more, and even more preferably 95% by mass or more.

[0029] (C) Sodium 2-acrylate cross-linked polymer and sodium carboxymethyl starch (C) is a water-soluble polymer. The tablet-shaped skin cleanser of the present invention contains either or both of (C) acrylate cross-linked polymer-2-sodium, carboxymethyl starch sodium, and exhibits excellent disintegration properties, and further can form a good paste.

[0030] The content of component (C) in the tablet-shaped skin cleanser of the present invention is not particularly limited, but is preferably 0.5% by mass or more and 15% by mass or less relative to the whole. When the content of component (C) is less than 0.5% by mass, the quality of the paste may sometimes decrease, and when it exceeds 15% by mass, the ease of rinsing may sometimes decrease. The proportion of component (C) relative to the whole is more preferably 1% by mass or more, further preferably 2% by mass or more, even more preferably 10% by mass or less, further preferably 7% by mass or less, and even more preferably 5% by mass or less.

[0031] Other ingredients The tablet-shaped skin cleanser of the present invention may also contain polyols, sugars, sugar alcohols, preservatives, metal ion chelating agents, active ingredients, expanders (excipients), disintegrants, lubricants, fragrances, etc., without impairing the effects of the present invention.

[0032] Examples of polyols, sugars, and sugar alcohols include glycerol, diglycerol, 1,3-butanediol (BG), propylene glycol, dipropylene glycol, 1,2-pentanediol, sorbitol, mannose, mannitol, galactose, galactitol, maltose, trehalose, erythritol, xylose, xylitol, sucrose, lactose, lactitol, and difructose anhydride.

[0033] Examples of preservatives include methylparaben and ethylparaben. Since the tablet-shaped skin cleanser of the present invention is water-free, bacteria do not easily multiply; therefore, the amount of preservative added relative to the total amount is preferably 0.5% by mass or less, more preferably 0.1% by mass or less, and most preferably no preservative is present.

[0034] Examples of metal ion chelating agents include disodium ethylenediaminetetraacetate, ethylenediaminetetraacetic acid, sodium ethylenediaminetetraacetate, and other ethylenediaminetetraacetic acid salts.

[0035] As active pharmaceutical ingredients, examples include vitamin C derivatives such as L-ascorbic acid, L-ascorbic acid phosphate, L-ascorbic acid monopalmitate, L-ascorbic acid dipalmitate, and L-ascorbic acid-2-glucoside; whitening agents such as glutathione and saxifrage extract; skin activators such as royal jelly and beech extract; blood circulation promoters such as capsaicin, gingerone, cantharides tincture, caffeine, tannic acid, and γ-oryzanol; anti-inflammatory agents such as glycyrrhizic acid derivatives and chamomile; and enzymes such as proteases and lysozyme chloride.

[0036] Examples of additives (excipients) that can be used to increase volume include lactose, magnesium aluminosilicate, calcium silicate, talc, kaolin, silicon dioxide, mica, zeolite, bentonite, titanium dioxide, and dextrin.

[0037] Examples of disintegrants include cross-linked carboxymethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, polyvinyl alcohol, polyacrylic acid, sodium polyacrylate, polymethacrylic acid, gum arabic, gelatin, agar, pullulan, and cross-linked polyvinylpyrrolidone.

[0038] Examples of lubricants include calcium stearate, stearase, and sucrose esters.

[0039] The tablet-shaped skin cleanser of the present invention can be compressed into tablets (tablets) using known methods.

[0040] Example The ingredients were blended according to the mass ratios shown in Tables 1-4, and compressed into tablets (approximately 800 mg) using a 300 kg press. The ingredients used are listed below.

[0041] (A) Rod-shaped crystalline cellulose Rod-shaped crystalline cellulose 1 [4.36, 50 μm, 49 degrees, 230%, 0.21 g / cm³] 3 ] (Made by Asahi Kasei Co., Ltd., CEOLUS ST-02) Rod-shaped crystalline cellulose 2 [4.70, 50 μm, 57 degrees, 290%, 0.12 g / cm³] 3 ] (Made by Asahi Kasei Co., Ltd., CEOLUS ST-100) (D) Other crystalline cellulose Crystalline cellulose 1 [2.45, 90 μm, 42 degrees, 240%, 0.29 g / cm³] 3 ] (Made by Asahi Kasei Co., Ltd., CEOLUSUF-F702) Crystalline cellulose 2 [2.57, 50 μm, 34 degrees, 240%, 0.23 g / cm³] 3 ] (Made by Asahi Kasei Co., Ltd., CEOLUSUF-F711) Crystalline cellulose 3 [2.37, 50 μm, 45 degrees, 200%, 0.29 g / cm³] 3 ] (Made by Asahi Kasei Co., Ltd., CEOLUSPH-101) Crystalline cellulose 4 [2.05, 90 μm, 42 degrees, 200%, 0.31 g / cm³] 3 ] (Made by Asahi Kasei Co., Ltd., CEOLUSPH-102) Crystalline cellulose 5 [1.97, 170 μm, 36 degrees, 200%, 0.34 g / cm³] 3 ] (Made by Asahi Kasei Co., Ltd., CEOLUSPH-200) Crystalline cellulose 6 [2.20, 50 μm, 41 degrees, 150%, 0.41 g / cm³] 3 ] (Made by Asahi Kasei Co., Ltd., CEOLUSFD-301) The values ​​in brackets [ ] represent aspect ratio, average particle size (μm), angle of repose (degrees), water absorption (% (w / w)), and bulk density (g / cm³). 3 ).

[0042] (B) Anionic surfactants Sodium lauroyl glutamate (manufactured by Asahi Kasei Finechem Co., Ltd., Aminosurfact ALMS-P1) Sodium lauroyl aspartate (made by Asahi Kasei FINECHEM Co., Ltd., AminoFoamer FLMS-P1) Potassium cocoyl glycinate (manufactured by Ajinomoto Co., Ltd., AMILITE GCK-11) Sodium cocoyl hydroxyethanesulfonate (Innospec Performance Chemicals, Pureact I-78) Potassium myristate (manufactured by MIYOSHI Oils and Fats Co., Ltd., COSMETICSOAP MF-K) (C) Sodium 2-acrylate crosspolymer (manufactured by Toa Synthetic Co., Ltd., ARON NT-Z) Sodium carboxymethyl starch (Rettenmaier Japan, VIVASTAR CS352SV) Other water-soluble high-molecular-weight sodium carbomer (sodium polyacrylate) (manufactured by Sumitomo Seika Co., Ltd., AQUPEC MGN40R) Sodium polyacrylate (Sensient Technologies Japan, COVACRYL MV 60) Polyvinyl alcohol (manufactured by Mitsubishi Chemical Corporation, Gohsenol EG-05) PVP (Ashland Specialty Ingredients, PVP K-30) Magnesium stearate (Magnesium Stearate-S, manufactured by NOF Co., Ltd.) Silica (Saint-Gobain Boron Nitride, AEROSIL R812) Mannitol (Mitsubishi Corporation Life Sciences, Ltd., Marincrystal) Evaluation Methods The resulting tablet-form skin cleanser was evaluated as follows. The evaluation results are shown in Tables 1-4.

[0043] • Formability Take the tablet-shaped skin cosmetic into your hand, observe its appearance visually, and evaluate its formability according to the following criteria.

[0044] <Evaluation Criteria> ○: The tablet surface is glossy and undamaged, and it retains its tablet shape after observation.

[0045] ×: The tablet surface is powdery, has defects, or cannot maintain its tablet shape after observation.

[0046] • Disintegration Divide the tablet-sized skin cleanser in half, add 2.5 mL of water, let stand for 5 seconds, then apply with the palm of your hand. Evaluate the disintegration according to the following criteria. Note that items rated "×" for disintegration were not further evaluated.

[0047] <Evaluation Criteria> ○: Disintegrates within 5 seconds of standing still.

[0048] △: Disintegrates upon application.

[0049] ×: Clumps may remain after application.

[0050] Usability Divide the tablet-sized skin cleanser in half, add 2.5 mL of water, let stand for 5 seconds, then apply with your palm and evaluate its usability according to the following criteria.

[0051] <Evaluation Items> 1) Spreadability (whether the cream can be spread smoothly and evenly) ○: Smooth, can be evenly spread.

[0052] △: Slightly rough, but can still be spread evenly.

[0053] ×: Not smooth, difficult to spread evenly.

[0054] 2) Massage properties during application (whether the cream feels thick and easy to massage) 〇: It has a substantial feel and is easy to massage.

[0055] △: It feels a bit heavy, but it's acceptable.

[0056] ×: Lacks a substantial feel and is difficult to massage.

[0057] 3) Irritation during application (whether there is a grainy feeling during application, and whether there is any physical irritation to the skin). 〇: No irritation.

[0058] △: There is a slight irritation, but it is acceptable.

[0059] ×: It has a stimulating effect.

[0060] 4) Ease of rinsing (Can it be quickly rinsed with water after use?) 〇: Rinse quickly.

[0061] △: Rinsing is a little slow but acceptable.

[0062] ×: Rinsing is slow.

[0063] 5) Moisturizing sensation after rinsing (After rinsing, does the skin feel moisturized instead of tight?) 〇: I feel a moisturizing sensation.

[0064] △: It has almost no moisturizing effect, but it is acceptable.

[0065] ×: No moisturizing effect.

[0066] [Table 1]

[0067] [Table 2]

[0068] [Table 3]

[0069] [Table 4]

[0070] "result" The tablet-shaped skin cleanser obtained in the examples containing rod-shaped crystalline cellulose has excellent usability, especially yielding a thick, creamy texture.

[0071] The tablet-shaped skin cleansers obtained in Comparative Examples 1-6, which contained only non-rod-shaped crystalline cellulose, had poor usability, especially lacking a thick, creamy texture. Furthermore, the tablet-shaped skin cleansers obtained in Comparative Examples 7-10, which did not contain ingredient (C), exhibited poor disintegration.

[0072] As specific examples of tablet-type skin cleansers, formulation examples are shown below. According to formulation examples 1 to 3, a tablet-type skin cleanser with excellent formability, disintegration properties, and the ability to form a smooth paste with excellent thickness and spreadability can be obtained, which also has excellent usability.

[0073] [Formulation Example 1] Tablet Mask Ingredient blending amount (mass%) Rod-shaped crystalline cellulose 77.05 Sodium lauroyl glutamate 2.00 Sodium stearoyl glutamate 0.80 Sodium cocoyl glutamate 0.20 Potassium cocoyl glycinate 2.00 Mannitol 13.00 Sodium 2-acrylate crosslinker 4.00 0.10g of protease Lipase 0.10 Magnesium stearate 0.25 0.50g of silicon dioxide [Formula Example 2] Tablet Mask Ingredient blending amount (mass%) Rod-shaped crystalline cellulose 79.65 Sodium lauroyl glutamate 3.00 Sodium cocoyl hydroxyacetate 1.00 Pullulan 0.50 Mannitol 5.00 Glucose 7.00 Sodium carboxymethyl starch 3.00 Carbon 0.10 Magnesium stearate 0.25 0.50g of silicon dioxide [Formula Example 3] Tablet Mask Ingredient blending amount (mass%) Rod-shaped crystalline cellulose 72.35 Sodium lauroyl glutamate 1.90 Sodium lauroyl aspartate 1.50 Sodium stearoyl glutamate 1.60 Sodium cocoyl glutamate 0.40 Sodium 2-acrylate crosslinker 3.00 0.50g agar Mannitol 14.00 Maltitol 4.00 Magnesium stearate 0.25 0.50g of silicon dioxide

Claims

1. A tablet-shaped skin cleanser, characterized in that, Contains (A) ~ (C): (A) Rod-shaped crystalline cellulose, (B) Anionic surfactants, (C) Sodium 2-acrylate cross-linked polymer and sodium carboxymethyl starch.

2. The tablet-shaped skin cleanser according to claim 1, characterized in that, It contains (D) other crystalline cellulose.

3. The tablet-shaped skin cleanser according to claim 1 or 2, characterized in that, Total crystalline cellulose, i.e., the ratio of A+D to the whole, is more than 45% by mass.

4. The tablet-shaped skin cleanser according to claim 1 or 2, characterized in that, (A) The ratio of rod-shaped crystalline cellulose to total crystalline cellulose, i.e., A+D, i.e., A / (A+D), is 15% or more by mass.

5. The tablet-shaped skin cleanser according to claim 1 or 2, characterized in that, (C) The proportion relative to the whole is more than 0.5% by mass and less than 15% by mass.

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