Agricultural preparation containing nicotine or bisamide compounds

Abstract

The invention belongs to the field of insecticides, and relates to an agricultural preparation containing nicotine or bisamide compounds. The preparation is prepared from an active ingredient, a surfactant and a functional additive, wherein the active component accounts for 0.2-60% of the mass of the preparation, and the active component is a nicotine compound. According to the invention, for a system for preparing corresponding seed treatment agents from nicotine and bisamide compounds, when a lignin auxiliary agent and starch are used in a compatible manner, an excellent effect of improving the adhesion capacity can be achieved at a proper proportion.

Description

[0001] The present application is a divisional application of a Chinese invention patent application, the original application date is August 28, 2023, the application number is 202311085929.4, the invention is named "Agricultural preparation containing nicotine or bisamide compound", the publication number is CN119522924A; due to the original application has the problem of single pointed out by the examiner, the applicant proposes a divisional application. TECHNICAL FIELD

[0002] The present application belongs to the field of insecticides, and relates to an agricultural preparation containing nicotine or bisamide compound. BACKGROUND

[0003] There are many types of underground pests, which are harmful and widely distributed, and are one of the important disasters in agricultural production. They mainly harm crops such as wireworms, grubs, golden needleworms, mole crickets, etc. Generally, they feed on plant roots, stems and leaves before sowing or during the growth of crops, causing damage to seedlings; during the growth of crops, they bite off seedlings, causing plants to die; after the harvest of crops, they harm seeds, fruits, etc. Underground pests not only harm the seeds, seedlings, roots and stems of crops, but also cause seedling and ridge breakage. Therefore, prevention and control is an important measure to ensure high and stable yield of crops.

[0004] Nicotine compounds are the key pesticides for the prevention and control of underground pests. Currently, nicotine compounds mainly used for the prevention and control of underground pests are imidacloprid, thiamethoxam, clothianidin and dinotefuran, among which imidacloprid, thiamethoxam and clothianidin are mainly used. The mechanism of action of nicotine insecticides is that they act as agonists of nicotinic acetylcholine receptors and selectively bind to acetylcholine receptors, compete with insect acetylcholine, block the normal conduction of central nervous system, and then cause insect paralysis and death. However, nicotine compounds have the problem of high solubility in water, which has been a long-term disadvantage for the application of seed coating agents. After seed coating, it is easy to be lost with rainwater, causing safety problems.

[0005] Since underground pests live and harm underground, they are hidden, and prevention and control should follow the principle of prevention first and comprehensive prevention. For prevention, the most effective way is pesticide control. Pesticide control generally uses two methods, one is seed dressing, which uses seed treatment technology, configures pesticide solution according to requirements, mixes with seeds, and dries completely before sowing, which can effectively control underground pests; the other is soil treatment, which uses granular agents containing active ingredients before sowing, and ensures uniform application on the ground and partial adsorption in the soil before sowing.

[0006] Both of these methods for controlling underground pests present issues related to the adhesion and degree of pesticide application. Whether it's seed dressing with pesticides that adhere to the seeds or mixing them around soil particles to maximize their adsorption in the soil, it's essential to effectively improve the pesticide's adhesion. Currently, the main methods for improving adhesion involve incorporating film-forming substances or polymers into the formulation. However, the actual effectiveness of these methods in enhancing adhesion, as well as the environmental problems caused by residues in the soil, need to be effectively addressed.

[0007] This problem has been a persistent challenge within the industry and requires further research and resolution. Summary of the Invention

[0008] The purpose of this invention is to provide an agricultural formulation for use with a nicotine- or diamide-based compound.

[0009] To achieve the above objectives, the present invention adopts the following technical solution: An agricultural formulation containing nicotinic or diamide compounds, the formulation comprising an active ingredient, a surfactant, and functional adjuvants; wherein the active ingredient accounts for 0.2-60% of the formulation mass, and the active ingredient is a nicotinic or diamide compound.

[0010] The functional additive is corn starch and / or potato starch.

[0011] The surfactant is selected from one or more of fatty alcohol polyoxyethylene ether, polyoxyethylene polyoxypropylene ether block copolymer, sorbitan fatty acid ester polyoxyethylene ether, and lignin sulfonate.

[0012] Furthermore, the surfactant is selected from one or more of the following: lignin sulfonate, high molecular weight carboxylate, naphthalene sulfonate, naphthalene sulfonate formaldehyde condensate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfonate, sodium dodecylbenzene sulfonate, sodium dodecyl sulfate, fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, polyoxyethylene polyoxypropylene ether block copolymer, and sorbitan fatty acid ester polyoxyethylene ether; for example, including but not limited to YUS-FS3000, Ultrazine NA, AEO-5, 127FL, Tween-80, Borresperse NA, etc.

[0013] Preferably, the surfactant is selected from lignin sulfonates; for example, Ultrazine NA and Borresperse NA.

[0014] The mass ratio of the active ingredient to the remaining components (total mass of surfactants and functional additives) is 10:1 to 1:1; the mass ratio of surfactants to functional additives is 2:1 to 3:1. The nicotinic compound is one or more of imidacloprid, thiamethoxam, and thiamethoxam; the diamide compound is compound A.

[0015] Compound A.

[0016] The formulation type may be seed treatment suspension, seed treatment emulsion, seed treatment dry powder, seed treatment microcapsule suspension, or granules.

[0017] The formulation may also contain other adjuvants, such as: The carrier is selected from one or more of the following: water, S150#, clay, diatomaceous earth, bentonite, magnesium aluminum silicate, precipitated silica, light calcium carbonate, and carbon dioxide.

[0018] It may also include thickening substances, such as xanthan gum, gelatin, gum arabic, polyvinyl acetate, polyvinylpyrrolidone, magnesium aluminum silicate, polyethylene glycol, phenolic resin, sodium polyacrylate, polyurea prepolymer, styrene-maleic anhydride copolymer, shellac, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, methyl cellulose, and sodium alginate, which can improve the stability of the formulation to a certain extent.

[0019] If required by the application, an antifoaming agent may be added. The antifoaming agent may be one or more of the following: SAG1522, silicones, C8-10 fatty alcohols, phosphate esters, C10-20 saturated fatty acids (such as decanoic acid), amides, or others.

[0020] If long-term storage is required, preservatives can be added, such as sodium benzoate, Kathon (2-methyl-4-isothiazolin-3-one and (B)5-chloro-2-methyl-4-isothiazolin-3-one), potassium sorbate, sodium dehydroacetate, or one or more of the following.

[0021] If the pH of the system needs to be adjusted, hydrochloric acid, sodium hydroxide, etc. can be added.

[0022] If color is required, a colorant can be added, which may include dyes, pigments (including color powder and color paste), etc.

[0023] Agricultural formulations can be seed treatment suspensions, seed treatment emulsions, seed treatment microcapsule suspensions, seed treatment dry powders, and granules.

[0024] The above-mentioned formulations can also be used in other formulations for the control of underground pests that require improved adhesion.

[0025] The adhesion ability, or adhesion degree, was determined in accordance with section 4.12 of the HG / T5443-2018 standard for thiamethoxam seed treatment suspension concentrate.

[0026] Compared with the prior art, the technical solution of the present invention has the following advantages: This invention discovers that for systems preparing seed treatment agents from nicotinic and diamide compounds, the use of lignin-based adjuvants in combination with starch in appropriate proportions can significantly enhance adhesion. Lignin, second only to cellulose in yield, is the most abundant aromatic compound obtainable from renewable resources, boasting outstanding global production capacity and being non-toxic and inexpensive. Lignin-based adsorbent materials represent one way to utilize lignin for high-value applications. Lignin can introduce various chemical groups through its phenolic hydroxyl groups to meet product requirements. Furthermore, both lignin and starch are biodegradable and environmentally friendly substances. Compared to existing film-forming additives used to address adhesion issues, this invention significantly improves adhesion and shortens drying time. Additionally, the adopted technical solution has significant environmental implications. Detailed Implementation

[0027] The following specific embodiments are provided to further illustrate the present invention, but the present invention is by no means limited to these examples. Methods well known to those skilled in the art are all included within the scope of the present invention. Percentages and parts in the formulation are all by weight. Compound A was prepared according to the relevant description in (CN 112457288 B), added at a 100% concentration, and the proportions of each component are by weight percentage. All other raw materials are commercially available products.

[0028] This invention aims to improve the adhesion of an insecticide to underground pests by using lignin and plant starch as key substances instead of conventionally used polymeric film-forming materials.

[0029] Formulation Examples Comparative Example 1-1.12% Imidacloprid Seed Treatment Suspension According to the formula requirements, 12% imidacloprid, 0.8% YUS-FS3000, 1% magnesium aluminum silicate, 0.2% xanthan gum, 5% red colorant, and 0.4% polyvinyl alcohol are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 12% imidacloprid seed treatment suspension.

[0030] Comparative Example 1-2.12% Imidacloprid Seed Treatment Suspension According to the formula requirements, 12% imidacloprid, 0.8% Ultrazine NA, 1% magnesium aluminum silicate, 0.2% xanthan gum, 5% warning colorant Red, and 0.4% polyvinyl alcohol are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 12% imidacloprid seed treatment suspension.

[0031] Example 1. 12% Imidacloprid Seed Treatment Suspension According to the formula requirements, 12% imidacloprid, 0.8% Ultrazine NA, 1% magnesium aluminum silicate, 0.2% xanthan gum, 5% warning colorant Red, and 0.4% corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 12% imidacloprid seed treatment suspension.

[0032] Comparative Example 2-1.20% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 20% thiamethoxam, 4% AEO-5, 0.8% magnesium aluminum silicate, 0.1% xanthan gum, 5% warning colorant Red, and 2% polyvinyl alcohol are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 20% thiamethoxam seed treatment suspension.

[0033] Comparative Example 2-2.20% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 20% thiamethoxam, 4% Ultrazine NA, 0.8% magnesium aluminum silicate, 0.1% xanthan gum, 5% warning colorant Red, and 2% polyvinyl alcohol are added to make up to 100% water. The mixture is then put into a sand mill for sand milling, and the output material is 20% thiamethoxam seed treatment suspension.

[0034] Example 2. 20% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 20% thiamethoxam, 4% Ultrazine NA, 0.8% magnesium aluminum silicate, 0.1% xanthan gum, 5% warning colorant Red, and 2% corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 20% thiamethoxam seed treatment suspension.

[0035] Comparative Example 3-1.30% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 30% thiamethoxam, 4% 127FL, 0.6% magnesium aluminum silicate, 0.12% xanthan gum, 7% red colorant, and 2% polyvinyl alcohol are added to make up to 100% water. The mixture is then put into a sand mill for sand milling, and the output material is 30% thiamethoxam seed treatment suspension.

[0036] Comparative Example 3-2.30% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 30% thiamethoxam, 4% Ultrazine NA, 0.6% magnesium aluminum silicate, 0.12% xanthan gum, 7% warning colorant Red, and 2% polyvinyl alcohol are added to make up to 100% water. The mixture is then put into a sand mill for sand milling, and the output material is 30% thiamethoxam seed treatment suspension.

[0037] Comparative Example 3-3. 30% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 30% thiamethoxam, 12% Ultrazine NA, 0.6% magnesium aluminum silicate, 0.12% xanthan gum, 7% warning colorant Red, and 3% corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 30% thiamethoxam seed treatment suspension.

[0038] Example 3. 30% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 30% thiamethoxam, 4% Ultrazine NA, 0.6% magnesium aluminum silicate, 0.12% xanthan gum, 7% warning colorant Red, and 2% corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 30% thiamethoxam seed treatment suspension.

[0039] Comparative Example 4 - 1.40% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 40% thiamethoxam A, 15% Tween-80, 0.2% magnesium aluminum silicate, 0.08% xanthan gum, 8% warning colorant Red, and 5% polyvinyl alcohol are added to make up to 100% water. The mixture is then put into a sand mill for sand milling, and the output material is 40% thiamethoxam seed treatment suspension.

[0040] Comparative Example 4 - 2.40% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 40% thiamethoxam, 15% Borresperse NA, 0.2% magnesium aluminum silicate, 0.08% xanthan gum, 8% warning colorant Red, and 5% polyvinyl alcohol are added to make up to 100% water. The mixture is then put into a sand mill for sand milling, and the output material is 40% thiamethoxam seed treatment suspension.

[0041] Example 4. 40% Thiamethoxam Seed Treatment Suspension According to the formula requirements, 40% thiamethoxam, 15% Borresperse NA, 0.2% magnesium aluminum silicate, 0.08% xanthan gum, 8% warning colorant Red, and 5% corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 40% thiamethoxam seed treatment suspension.

[0042] Comparative Example 5. 10% Thiamethoxam Granules According to the formula requirements, 10% thiamethoxam and 8% diatomaceous earth are mixed to obtain a master powder. Then, 5% polyvinyl alcohol and quartz sand are added and mixed to obtain 10% thiamethoxam granules.

[0043] Example 5. 10% Thiamethoxam Granules According to the formula requirements, 10% thiamethoxam and 8% diatomaceous earth are mixed to obtain a master powder. Then, 5% corn starch, 10% Borresperse NA and quartz sand are added and mixed to obtain 10% thiamethoxam granules.

[0044] Comparative Example 6 - 1.60% Imidacloprid Seed Treatment Suspension According to the formula requirements, 60% imidacloprid, 15% SP 27001, 0.1% magnesium aluminum silicate, 0.06% xanthan gum, 9% warning colorant Red, and 5% polyvinyl alcohol are added to make up to 100% water. The mixture is then put into a sand mill for sand milling, and the output material is 60% imidacloprid seed treatment suspension.

[0045] Comparative Example 6 - 2.60% Imidacloprid Seed Treatment Suspension According to the formula requirements, 60% imidacloprid, 15% Borresperse NA, 0.1% magnesium aluminum silicate, 0.06% xanthan gum, 9% warning colorant Red, and 5% polyvinyl alcohol are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 60% imidacloprid seed treatment suspension.

[0046] Comparative Example 6-3. 60% Imidacloprid Seed Treatment Suspension According to the formula requirements, 60% imidacloprid, 15% Borresperse NA, 0.1% magnesium aluminum silicate, 0.06% xanthan gum, 9% warning colorant Red, and 3% corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 60% imidacloprid seed treatment suspension.

[0047] Example 6. 60% Imidacloprid Seed Treatment Suspension According to the formula requirements, 60% imidacloprid, 15% Borresperse NA, 0.1% magnesium aluminum silicate, 0.06% xanthan gum, 9% warning colorant Red, and 5% corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 60% imidacloprid seed treatment suspension.

[0048] Comparative Example 7. 0.5% Compound A granules According to the formula requirements, 0.5% of compound A and 8% of diatomaceous earth are mixed to obtain a master powder. Then, 5% polyvinyl alcohol and quartz sand are added and mixed to obtain 0.5% compound A granules.

[0049] Example 7. 0.5% Compound A Granules According to the formula requirements, 0.5% of compound A and 8% of diatomaceous earth are mixed to obtain a master powder. Then, 5% corn starch, 10% Borresperse NA and quartz sand are added and mixed to obtain 0.5% compound A granules.

[0050] Comparative Example 8 - 1.12% Compound A Seed Treatment Suspension According to the formula requirements, compound A 12%, YUS-FS3000 0.8%, magnesium aluminum silicate 1%, xanthan gum 0.2%, warning color agent Red 5%, and polyvinyl alcohol 0.4% are added to make up to 100% with water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 12% compound A seed treatment suspension.

[0051] Comparative Example 8 - 2.12% Compound A seed treatment suspension According to the formula requirements, 12% of compound A, 0.8% of Ultrazine NA, 1% of magnesium aluminum silicate, 0.2% of xanthan gum, 5% of warning colorant Red, and 0.4% of polyvinyl alcohol are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 12% compound A seed treatment suspension.

[0052] Example 8.12% Compound A Seed Treatment Suspension According to the formula requirements, 12% of compound A, 0.8% of Ultrazine NA, 1% of magnesium aluminum silicate, 0.2% of xanthan gum, 5% of colorant Red, and 0.4% of corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 12% compound A seed treatment suspension.

[0053] Example 9. 12% Compound A Seed Treatment Microcapsule Suspension According to the formula requirements, the following components are added: 12% Compound A, 0.8% Ultrazine NA, 2.5% Sodium polyacrylate, 8% Polyurea prepolymer, 1% Styrene-maleic anhydride copolymer, 10% S150#, 3% Hydrochloric acid, 0.01% Sodium hydroxide, 0.01% Xanthan gum, 5% Red colorant, and 0.4% Corn starch. Water is added to make up to 100% according to the formula ratio. The mixture is then added to the sand mill slurry and stirred evenly to obtain 12% Compound A seed treatment microcapsule suspension.

[0054] Comparative Example 10-1.20% Compound A Seed Treatment Suspension According to the formula requirements, 20% of compound A, 4% of AEO-5, 0.8% of magnesium aluminum silicate, 0.1% of xanthan gum, 5% of warning color agent Red, and 2% of polyvinyl alcohol are added to make up to 100% with water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 20% of compound A seed treatment suspension.

[0055] Comparative Example 10-2.20% Compound A Seed Treatment Suspension According to the formula requirements, 20% of compound A, 4% of Ultrazine NA, 0.8% of magnesium aluminum silicate, 0.1% of xanthan gum, 5% of warning color agent Red, and 2% of polyvinyl alcohol are added to make up to 100% with water. The mixture is then put into a sand mill for sand milling, and the output material is 20% of compound A seed treatment suspension.

[0056] Example 10.20% Compound A Seed Treatment Suspension According to the formula requirements, 20% of compound A, 4% of Ultrazine NA, 0.8% of magnesium aluminum silicate, 0.1% of xanthan gum, 5% of colorant Red, and 2% of corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 20% compound A seed treatment suspension.

[0057] Comparative Example 11 - 1.30% Compound A Seed Treatment Suspension According to the formula requirements, 30% of compound A, 4% of 127FL, 0.6% of magnesium aluminum silicate, 0.12% of xanthan gum, 7% of warning color agent Red, and 2% of polyvinyl alcohol are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 30% of compound A seed treatment suspension.

[0058] Comparative Example 11 - 2.30% Compound A Seed Treatment Suspension According to the formula requirements, 30% of compound A, 4% of Ultrazine NA, 0.6% of magnesium aluminum silicate, 0.12% of xanthan gum, 7% of warning color agent Red, and 2% of polyvinyl alcohol are added to make up to 100% with water. The mixture is then put into a sand mill for sand milling, and the output material is 30% of compound A seed treatment suspension.

[0059] Comparative Example 11-3. 30% Compound A Seed Treatment Suspension According to the formula requirements, 30% of compound A, 12% of Ultrazine NA, 0.6% of magnesium aluminum silicate, 0.12% of xanthan gum, 7% of colorant Red, and 2% of corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 30% of compound A seed treatment suspension.

[0060] Example 11. 30% Compound A Seed Treatment Suspension According to the formula requirements, 30% of compound A, 4% of Ultrazine NA, 0.6% of magnesium aluminum silicate, 0.12% of xanthan gum, 7% of colorant Red, and 2% of corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 30% of compound A seed treatment suspension.

[0061] Example 12. 30% Compound A Seed Treatment Emulsion According to the formula requirements, the following ingredients are added: 30% Compound A, 4% 127 FL, 0.8% Ultrazine NA, 25% S150#, 5% Red colorant, and 2.4% corn starch. Water is added to 100% according to the formula ratio. The mixture is then sheared at 12,000 rpm for 15 minutes to obtain a 30% Compound A seed treatment emulsion.

[0062] Comparative Example 13 - 1.40% Compound A Seed Treatment Suspension According to the formula requirements, 40% of compound A, 15% of Tween-80, 0.2% magnesium aluminum silicate, 0.08% xanthan gum, 8% of warning colorant Red, and 5% of polyvinyl alcohol are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 40% compound A seed treatment suspension.

[0063] Comparative Example 13 - 2.40% Compound A Seed Treatment Suspension According to the formula requirements, 40% of compound A, 15% of Borresperse NA, 0.2% magnesium aluminum silicate, 0.08% xanthan gum, 8% of warning colorant Red, and 5% of polyvinyl alcohol are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 40% compound A seed treatment suspension.

[0064] Example 13. 40% Compound A Seed Treatment Suspension According to the formula requirements, 40% of compound A, 15% of Borresperse NA, 0.2% magnesium aluminum silicate, 0.08% xanthan gum, 8% of warning colorant Red, and 5% of corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 40% compound A seed treatment suspension.

[0065] Comparative Example 14 - 1.60% Compound A Seed Treatment Suspension According to the formula requirements, 60% of compound A, 15% of SP 27001, 0.1% of magnesium aluminum silicate, 0.06% of xanthan gum, 9% of warning colorant Red, and 5% of polyvinyl alcohol are added to make up to 100% with water. The mixture is then put into a sand mill for sand milling, and the output material is 60% compound A seed treatment suspension.

[0066] Comparative Example 14 - 2.60% Compound A Seed Treatment Suspension According to the formula requirements, 60% of compound A, 15% of Borresperse NA, 0.1% of magnesium aluminum silicate, 0.06% of xanthan gum, 9% of warning colorant Red, and 5% of polyvinyl alcohol are added to make up to 100% with water. The mixture is then put into a sand mill for sand milling, and the output material is 60% of compound A seed treatment suspension.

[0067] Example 14. 60% Compound A Seed Treatment Suspension According to the formula requirements, 60% of compound A, 15% of Borresperse NA, 0.1% of magnesium aluminum silicate, 0.06% of xanthan gum, 9% of warning colorant Red, and 5% of corn starch are added to make up to 100% water according to the formula ratio. The mixture is then put into a sand mill for sand milling, and the output material is 60% compound A seed treatment suspension.

[0068] Example 15. 60% Compound A Seed Treatment Dry Powder According to the formula requirements, 60% of compound A, 15% Borresperse NA, 0.5% rose essence, 2% diatomaceous earth, 7.5% corn starch, and the balance of light calcium carbonate to make up to 100% are obtained by air jet milling to obtain 60% compound A seed treatment dry powder.

[0069] Application performance testing: The seed treatment agent described in the above embodiments was used to coat corn seeds, and the following properties were measured after coating.

[0070] The method involves pouring the coated sample through an upper glass funnel onto a guide gate. The gate is then opened, allowing the seeds to fall freely at a fixed height onto a sieve. The pesticide powder detached from the seeds is separated by the sieve. This process is repeated five times. The residual pesticide content on the seeds is measured and compared with the pesticide dosage on untested seeds to calculate the pesticide adhesion. The adhesion testing apparatus used is detailed in the thiamethoxam seed treatment suspension standard HG / T 5443-2018.

[0071] Weigh 100 g of corn seeds (accurate to 1 g) into a petri dish. Using a syringe, draw 0.33 g of the sample and inject it into a beaker. Add 9.67 g of deionized water and mix thoroughly. Take 1 g of the seed treatment agent sample mixture prepared in the above examples and inject it into the petri dish. Cover and shake for 1 min. Spread the coated seeds out flat and allow the solution to dry until ready for use.

[0072] 330 g of seeds treated as described above were stored at a temperature of (23±5)℃ and a relative humidity of 40%~60% for at least 24 h.

[0073] Weigh three 20 g portions of the prepared seed sample into three conical flasks, add 50 mL of methanol, and sonicate until the dye on the seed surface is completely dissolved. Remove the flasks, let stand for 10 min or centrifuge, and determine the mass of the active ingredient.

[0074] The remaining 270 g of seeds were divided into three equal portions, and the following test was conducted: 90 g of the sample was slowly poured into a cylindrical glass guide channel through the upper glass funnel. When all seeds reached the bottom of the guide channel, the partition was opened, allowing the seeds to fall freely onto a sieve. The partition was then closed. The experimental apparatus did not need to be cleaned during the seed drop process. This process was repeated four times. 20 g of the sample was taken for testing the seed dosage. Before conducting the next batch of sample experiments, residual powder was cleaned from the guide channel, sieve, and apparatus. The above experimental procedure was repeated for the remaining two portions of the sample. After the drop test, three 20 g portions of each sample were placed in three conical flasks, 50 mL of methanol was added, and the mixture was ultrasonically vibrated until the dye on the seed surface was completely dissolved. The flasks were then removed, allowed to stand for 10 min, or centrifuged, and the mass of the active ingredient was determined.

[0075] Adhesion is calculated according to formula (1): ……………………(1) In the formula: 2 —The adhesion of the sample, in percentage (%); m’ —The average mass of the effective component in three samples after the drop test, expressed in grams (g). m —The average mass of the active ingredient in three samples that have not undergone drop testing, expressed in grams (g).

[0076] Table 1 shows the adhesion data of seeds coated with the formulations prepared in the examples. As can be seen from the data in the table, the schemes in bold all adopted the formulation system of lignin sulfonate combined with corn starch, which significantly improved the adhesion. Moreover, under the appropriate ratio, it has a significant effect on improving the adhesion.

[0077] Table 1. Coated Seed Adhesion

[0079] The data in the table shows that among the three schemes of using polyvinyl alcohol alone, lignin plus polyvinyl alcohol, and lignin plus starch, only the formulation using lignin sulfonate combined with corn starch showed a significant improvement in adhesion value, and the improvement was even more obvious under appropriate ratios.

[0080] Further performance testing was conducted on the above-obtained seed pack formulation: The corn seeds coated in Examples 6 and 11 were tested for germination safety using the formulations at dosages of 200 ml / 100 kg and 600 ml / 100 kg of seeds, respectively. This invention was conducted according to GB / T3543.4-1995, the "Specifications for the Inspection of Crop Seeds—Germination Test." Germination refers to the emergence and growth of seedlings to a certain stage in the laboratory, with the main structure of the seedling indicating its potential to further develop into a normal plant under suitable field conditions. Germination potential refers to the germination trend, observed on the 4th day according to relevant standards. Germination rate is the percentage of normal seedlings that develop within specified conditions and time out of the total number of seeds tested.

[0081] Sand was used as the germination bed in the experiment. The sand particles were uniform in size, with a diameter of 0.05-0.80 mm, and the seeds were non-toxic and sterile. They were washed and sterilized at high temperature before use. The sand bed was prepared using a sand-in-sand method, that is, the seeds were sown on a layer of flat, damp sand, and then covered with a 10-20 mm thick layer of loose sand, depending on the size of the seeds.

[0082] The germination equipment is a germination box: it has light and a temperature control range of 10-40 ℃; According to the germination conditions specified in the standard, the germination potential and germination rate were measured at a low temperature of 20 ℃, both day and night.

[0083] Germination vigor is the percentage of seedlings that have emerged 4 days after planting. Germination rate is the percentage of seedlings that emerge 7 days after planting.

[0084] The blank portion refers to uncoated seeds that have not been coated with any pesticide.

[0085] Table 2 Safety data for Examples 6 and 10

[0086] As shown in Table 2, under this technical solution, the seeds coated with the formulations in the examples according to the high and low seed ratios can germinate normally, and the germination rate is comparable to or slightly higher than that of the blank seeds, without affecting the germination rate.

Claims

1. An agricultural formulation containing nicotinic acid or diamide compounds, characterized in that: The formulation comprises an active ingredient, a surfactant, and functional additives; wherein the active ingredient accounts for 0.2-60% of the formulation mass, and the active ingredient is a nicotine compound.

2. The agricultural formulation containing nicotinic acid or diamide compounds according to claim 1, characterized in that: The functional additive is corn starch and / or potato starch.

3. The agricultural formulation containing nicotinic acid or diamide compounds according to claim 1, characterized in that: The surfactant is selected from one or more of fatty alcohol polyoxyethylene ether, polyoxyethylene polyoxypropylene ether block copolymer, sorbitan fatty acid ester polyoxyethylene ether, and lignin sulfonate.

4. The agricultural formulation containing nicotinic or diamide compounds according to any one of claims 1-3, characterized in that: The mass ratio of the active ingredient to the remaining components (total mass of surfactant and functional additives) is 10:1 to 1:1; the mass ratio of surfactant to functional additives is 2:1 to 3:

1.

5. The agricultural formulation containing nicotinic acid or diamide compounds according to claim 4, characterized in that: The nicotinic compounds are one or more of imidacloprid, thiamethoxam, and thiamethoxam.

6. The agricultural formulation containing nicotinic acid or diamide compounds according to claim 1, characterized in that: The formulation type may be seed treatment suspension, seed treatment emulsion, seed treatment dry powder, seed treatment microcapsule suspension, or granules.

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