Deep repairing and anti-aging composition containing edelweiss alpina and peony seed oil and application of deep repairing and anti-aging composition

Abstract

The invention relates to a deep repairing and anti-aging composition containing edelweiss alpina and peony seed oil and application of the deep repairing and anti-aging composition, and belongs to the technical field of cosmetics. The deep-repairing and anti-aging composition provided by the invention comprises the edelweiss alpine extract, the peony seed oil, the picea exfoliata extract and the desert rose leaf cell extract, and the four components are mutually matched, so that the deep-repairing and anti-aging composition has good deep-repairing and anti-aging effects, can be applied to repairing and anti-aging skin care products, and has a good application prospect.

Description

Technical Field

[0001] This invention belongs to the field of cosmetic technology and relates to a deep repair and anti-aging composition containing Edelweiss and peony seed oil and its application. Background Technology

[0002] Skin aging is a complex phenomenon involving multiple biological processes, essentially stemming from the gradual disruption of homeostasis in cells and tissue structures across molecular, metabolic, and defense systems. As research deepens, the academic community increasingly recognizes that aging is not the result of a single pathway, but rather a systemic functional decline influenced by a complex interplay of genetic programming, environmental exposure, and lifestyle factors. This process manifests on the skin as the formation of fine lines and wrinkles, loss of elasticity, decreased firmness, and weakened repair capabilities. Traditional anti-aging strategies often focus on single targets, such as neutralizing free radicals with antioxidants or stimulating collagen synthesis with ingredients like retinol. While these methods are effective to some extent, their limitations are significant: firstly, targeting a single mechanism cannot comprehensively address the complexity of the aging network, often improving only superficial symptoms without addressing the root cause; secondly, many potent ingredients, due to their direct and highly irritating mechanisms, are unsuitable for individuals with already compromised skin barrier function or those in a sensitive state. Such individuals are prone to adverse reactions such as redness, stinging, and further barrier damage after use, thus falling into the dilemma of "damaging the skin in the pursuit of anti-aging." Therefore, one of the core challenges facing the field of skincare science today is how to develop a solution that can intervene in the core aging mechanisms through multiple pathways and in a synergistic manner to achieve deep repair and anti-aging. Summary of the Invention

[0003] The purpose of this invention is to provide a deep repair and anti-aging composition containing Edelweiss and Peony seed oil and its application. The deep repair and anti-aging composition includes Edelweiss extract, Peony seed oil, Snow Mountain Spruce extract, and Desert Rose leaf cell extract. The four components work together to exert excellent deep repair and anti-aging effects.

[0004] The objective of this invention can be achieved through the following technical solutions: In a first aspect, the present invention provides a deep repair and anti-aging composition containing Edelweiss and Peony seed oil, the deep repair and anti-aging composition comprising the following components: Edelweiss extract, Peony seed oil, Snow spruce extract, and Desert Rose leaf cell extract, wherein the weight ratio of Edelweiss extract, Peony seed oil, Snow spruce extract, and Desert Rose leaf cell extract is (3-6):(0.5-2):(1.5-3):(0.2-0.6).

[0005] Preferably, the weight ratio of the Edelweiss extract, peony seed oil, spruce extract, and desert rose leaf cell extract is (4-5):(1-1.5):(2.2-2.6):(0.3-0.4).

[0006] Secondly, the present invention provides the application of the deep repair and anti-aging composition containing Edelweiss and peony seed oil described in the first aspect in the preparation of skin care products, wherein the skin care products include any one of toner, cream, mask, lotion, and spray, and the amount of the deep repair and anti-aging composition added is 1%-3% of the total weight of the skin care products.

[0007] Thirdly, the present invention provides an emulsion comprising the following raw materials by weight percentage: 1%-3% of the deep repair and anti-aging composition described in the first aspect, 5-12% oil, 3%-10% moisturizer, 0.05%-0.5% thickener, 3%-5% emulsifier, 0.05%-0.3% preservative, and the balance being deionized water.

[0008] Preferably, the oil is selected from one or more of caprylic / capric triglycerides, squalane, jojoba seed oil, macadamia nut oil, olive oil, and cyclopentamethoxysiloxane.

[0009] Preferably, the moisturizer is selected from one or more of glycerin, dipropylene glycol, allantoin, panthenol, trehalose, and betaine.

[0010] Preferably, the thickener is selected from one or more of cetearyl alcohol, xanthan gum, carbomer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, and ammonium acryloyldimethyl taurate / VP copolymer.

[0011] Preferably, the emulsifier is selected from one or more of glyceryl stearate, methyl glucose sesquistearate, PEG-20 methyl glucose sesquistearate, C12-20 alkyl glucoside, and sucrose stearate.

[0012] Preferably, the preservative is selected from one or more of methylparaben, propylparaben, bis(hydroxymethyl)imidazolidinyl urea, 1,2-hexanediol, and p-hydroxyacetophenone.

[0013] The beneficial effects of this invention are: The deep repair and anti-aging composition provided by this invention includes Edelweiss extract, peony seed oil, spruce extract, and Rosa desertica leaf cell extract. Among these, Edelweiss extract is rich in flavonoids, phenolic acids, and other active ingredients, which can effectively enhance skin resistance, reduce free radical production, promote collagen production to delay aging, deeply repair damaged skin tissue, and form a water-retaining film on the skin surface to achieve moisturizing effects. Rosa desertica leaf cell extract can activate the skin cell's own vitality, promote epidermal cell renewal, and help... It protects the elastic fibers in the skin from excessive degradation, penetrates deep into the skin to prolong the cell activity cycle, and deeply combats aging; peony seed oil is rich in unsaturated fatty acids and has excellent antioxidant, anti-inflammatory, and soothing properties, which can effectively reduce discomfort such as burning and stinging caused by barrier damage, stabilize the skin condition, and delay the skin aging process. While providing basic hydration, it repairs and strengthens the damaged barrier; spruce extract further provides soothing and antioxidant effects, synergistically strengthening the skin's defense network; the four ingredients work together to exert excellent deep repair and anti-aging effects. Detailed Implementation

[0014] To further illustrate the technical means and effects of the present invention in achieving its intended purpose, the following detailed description of the specific implementation methods, structures, features, and effects of the present invention, in conjunction with embodiments, is provided below.

[0015] Edelweiss extract was purchased from Baoji Liupanyun Biotechnology Co., Ltd. Peony seed oil was purchased from Wuhan Beileye Biomedical Technology Co., Ltd. The Norwegian spruce extract was purchased from Nanjing Urban Agriculture Technology Development Co., Ltd., and its INCI is Norway spruce (PICEA EXCELSA) leaf extract, which is obtained by compounding 99.5% Norway spruce (PICEA EXCELSA) leaf extract with 0.5% hexanediol. The desert rose leaf cell extract was purchased from Naolys, France, and was obtained by combining 20 wt% desert rose (ADENIUM OBESUM) leaf cell extract and 80 wt% glycerol.

[0016] Unless otherwise specified, all other materials, reagents, etc. used in all embodiments and comparative examples of this invention are commercially available.

[0017] The components and their weight ratios of the deep repair and anti-aging compositions of Examples 1-5 and Comparative Examples 1-6 are shown in Table 1, and the total weight of each composition is equal. Each component in each embodiment and each comparative example is mixed evenly according to the formula amount to obtain the deep repair and anti-aging composition corresponding to each embodiment and each comparative example.

[0018] Table 1. Components and weight ratios of the composition Group Edelweiss extract Peony seed oil Snowy Spruce Extract Desert Rose Leaf Cell Extract Example 1 4.5 1.25 2.4 0.35 Example 2 4 1 2.2 0.3 Example 3 5 1.5 2.6 0.4 Example 4 3 0.5 1.5 0.2 Example 5 6 2 3 0.6 Comparative Example 1 0 1.25 2.4 0.35 Comparative Example 2 4.5 0 2.4 0.35 Comparative Example 3 4.5 1.25 0 0.35 Comparative Example 4 4.5 1.25 2.4 0 Comparative Example 5 2 0.3 4 0.1 Comparative Example 6 7 3 1 1 Comparative Example 7 Compared with Example 1, the only difference in Comparative Example 7 is that an equal weight of oat peptides (Lanzhou Waterles Biotechnology Co., Ltd.) was used instead of Edelweiss extract, while other conditions remained the same as in Example 1.

[0019] Comparative Example 8 Compared with Example 1, the only difference is that Comparative Example 8 uses an equal weight of flaxseed oil (Harbin Aisen Biotechnology Co., Ltd.) instead of peony seed oil, while other conditions remain the same as in Example 1.

[0020] Comparative Example 9 Compared with Example 1, the only difference is that Comparative Example 9 uses an equal weight of grape seed extract (Lanzhou Waterles Biotechnology Co., Ltd.) instead of spruce extract, while other conditions remain the same as in Example 1.

[0021] Comparative Example 10 Compared with Example 1, the only difference is that Comparative Example 10 uses an equal weight of Panax notoginseng extract (Lanzhou Waterles Biotechnology Co., Ltd.) instead of Rosa desertica leaf cell extract, while other conditions remain the same as in Example 1.

[0022] Test Example 1: HaCaT Cell ROS Assay 1) HaCaT cells (Shanghai Guyan Industrial Co., Ltd.) at 1×10 5 After seeding each well of a 6-well plate, the samples were cultured in DMEM containing 10% v / v FBS at 37°C and 5% CO2 for 24 hours. Then, the samples were divided into groups and administered the drug. Each group had 3 replicates. 2 mL of liquid was added to each well. The blank control group was given complete DEME culture medium in each well, the model group was given complete DEME culture medium containing 300 μM H2O2 in each well, and the sample group was given complete DEME culture medium containing 0.01 wt% of the deep repair and anti-aging composition prepared in Examples 1-5 or Comparative Examples 1-10 and 300 μM H2O2 in each well. After completion, the samples were cultured in DMEM culture medium at 37°C and 5% CO2 for another 24 hours. 2) After induction, wash cells three times with PBS, add 1 mL of 10 μM DCFH-DA probe to each well, incubate at 37℃ and 5% CO2 for 30 min, discard the culture medium containing DCFH-DA, wash three times with PBS, digest cells with 0.25% trypsin, wash cells once with PBS, add a certain amount of fresh PBS, perform flow cytometry detection, and calculate the downregulation rate according to the following formula: Downregulation rate % = (Model group - Sample group or blank control group) / Model group × 100%; The results, after taking the average, are recorded in Table 2 below.

[0023] Table 2. ROS test results of HaCaT cells ROS downgrade rate / % Blank control group 19.5 Example 1 14.8 Example 2 13.9 Example 3 14.3 Example 4 12.7 Example 5 13.4 Comparative Example 1 4.1 Comparative Example 2 5.3 Comparative Example 3 4.8 Comparative Example 4 5.5 Comparative Example 5 8.7 Comparative Example 6 10.5 Comparative Example 7 6.4 Comparative Example 8 7.3 Comparative Example 9 6.9 Comparative Example 10 7.5 As shown in Table 2, the ROS downregulation rate in the blank control group was 19.5%, indicating that the ROS content in the model group was significantly upregulated compared to the blank control group, demonstrating the successful establishment of the experimental model. Compared to Comparative Examples 1-10, the deep repair and anti-aging compositions provided in Examples 1-5 significantly downregulated the level of reactive oxygen species in HaCaT cells induced by hydrogen peroxide, exhibiting excellent antioxidant capacity and thus protecting the skin from oxidative stress damage.

[0024] As can be seen from the comparison of Example 1 and Comparative Examples 1-4, there is a clear synergistic effect among the four components of the composition: Edelweiss extract, Peony seed oil, Snowy Spruce extract, and Desert Rose leaf cell extract. The absence of any one component will lead to a decline in antioxidant efficacy to varying degrees. As can be seen from the comparison of Example 1 and Comparative Examples 5-10, the composition of the present invention is specific in the selection of component types and dosage ratios. Even if extracts with similar efficacy are used for equal substitution, the antioxidant effect cannot reach the level of the original combination, indicating that the synergistic antioxidant network achieved by the present invention through unique formulation cannot be easily replaced.

[0025] Test Example 2: Cell Scratch Test HaCaT cells (Shanghai Yaji Biotechnology) were seeded in 12-well plates and cultured in DMEM complete medium at 37℃ and 5% CO2 for 24 h. A cell scratch model was created by placing a plug into each well of the cell plate and cultured for another 24 h. The old medium was removed, and the cells were washed twice with PBS. The cells were then divided into a blank control group, a positive control group, and a sample group, with three replicates per group. The blank control group received 2 mL of serum-free DMEM medium, the positive control group received 2 mL of serum-free DMEM medium with an EGF concentration of 10000 IU / mL, and the sample group received 2 mL of serum-free DMEM medium containing 1 wt% of the deep repair and anti-aging composition prepared in Examples 1-5 or Comparative Examples 1-10. Cell growth at the scratch sites was observed under a microscope at 0 h and 24 h, and photographs were taken. The healing area was calculated using ImageJ software, and the repair ability of each group was evaluated by the healing rate. The healing rate was calculated using the following formula: Healing rate % = (scratch area at 0h - scratch area at 24h) / scratch area at 0h; The results, after taking the average, are recorded in Table 3 below.

[0026] Table 3. Results of Cell Scratch Test Healing rate / % Blank group 20.1 Positive control group 100% Example 1 75.2 Example 2 72.4 Example 3 73.9 Example 4 68.5 Example 5 70.6 Comparative Example 1 46.3 Comparative Example 2 50.7 Comparative Example 3 48.4 Comparative Example 4 51.6 Comparative Example 5 60.9 Comparative Example 6 63.1 Comparative Example 7 53.7 Comparative Example 8 56.2 Comparative Example 9 54.5 Comparative Example 10 57.8 As shown in Table 3, compared with Comparative Examples 1-10, the deep repair and anti-aging compositions provided in Examples 1-5 can promote the healing of HaCaT cells and have repair potential.

[0027] Among them, by comparing Example 1 and Comparative Examples 1-10, it can be seen that the healing rate of the composition decreases when any component is omitted or replaced. This indicates that the four extracts in the deep repair and anti-aging composition of the present invention are indispensable in promoting the repair process and have a synergistic effect. Moreover, the repair effect of the composition is optimal when the weight ratio of Edelweiss extract, Peony seed oil, Snowy Spruce extract and Desert Rose leaf cell extract is (3-6):(0.5-2):(1.5-3):(0.2-0.6).

[0028] Test Example 3: Effects on Type I Collagen Test method: Human skin fibroblasts (HSF) (Shanghai Yaji Biotechnology) were resuscitated and cultured in DMEM high-glucose medium containing 10% v / v FBS. The cells were then cultured at 37°C in a 5% CO2 incubator and passaged at a ratio of 1:3. HSF cells in the logarithmic growth phase were digested, resuspended, and counted at a ratio of 1×10⁻⁶. 5 Cells were seeded per well in 96-well plates, and DMEM high-glucose medium containing 10% v / v FBS was added. The plates were incubated overnight at 37°C and 5% CO2 to allow adherence. The old medium was discarded, and the cells were gently washed once with 200 μL of PBS. The cells were then divided into a control group and a sample group, with three replicates per group. The sample group was incubated with 200 μL of medium containing 0.1 wt% of the corresponding test sample (the corresponding test sample was the deep repair and anti-aging composition prepared in each example and comparative example; the sample was dissolved in DMSO and then diluted with DMEM medium). The control group was incubated with only 200 μL of DMEM medium. The plates were incubated in a CO2 incubator for 24 h. After incubation, 200 μL of cell culture supernatant was collected from each well into a 1.5 mL sterile centrifuge tube. The type I collagen content was detected according to the instructions of the Human Type I Collagen Enzyme-Linked Immunosorbent Assay Kit (Lianmai Biotechnology, catalog number LM-16333-ES), and the upregulation rate was recorded. The formula for calculating the upregulation rate is: Upward adjustment rate % = [(TC) / C] × 100%; In the formula, T is the average type I collagen content of the sample, and C is the average type I collagen content of the blank group; The results, after taking the average, are recorded in Table 4 below.

[0029] Table 4. Test results on the effect on type I collagen Upward adjustment rate / % Blank group / Example 1 148.6 Example 2 136.5 Example 3 144.8 Example 4 110.9 Example 5 125.4 Comparative Example 1 58.7 Comparative Example 2 62.1 Comparative Example 3 60.5 Comparative Example 4 62.6 Comparative Example 5 70.3 Comparative Example 6 72.8 Comparative Example 7 65.7 Comparative Example 8 69.2 Comparative Example 9 67.3 Comparative Example 10 69.5 As shown in Table 4, compared with Comparative Examples 1-10, the deep repair and anti-aging compositions provided in Examples 1-5 can effectively promote the production of type I collagen in human skin fibroblasts, thereby tightening the skin, improving wrinkles, and exerting anti-aging effects. Furthermore, the composition exhibits the best anti-aging effect when the weight ratio of Edelweiss extract, Peony seed oil, Snowy Spruce extract, and Desert Rose leaf cell extract is 4.5:1.25:2.4:0.35.

[0030] Application Example 1-5 and Comparative Application Example 1-10 The deep repair and anti-aging compositions of Examples 1-5 and Comparative Examples 1-10 were added to the emulsions to obtain application examples 1-5 and comparative application examples 1-10, respectively. In addition, an emulsion without the addition of the deep repair and anti-aging composition was prepared as a blank application example. The formulation of the emulsions is shown in Table 5.

[0031] Table 5. Emulsion components and dosage

[0032] The preparation of emulsions in Application Examples 1-5 and Comparative Application Examples 1-10 includes the following steps: S1. Mix deionized water and thickener evenly, add humectant, heat to 75℃, and stir evenly to obtain aqueous phase; S2. Heat the emulsifier to 75°C, stir until melted, add the oil, stir evenly to obtain the oil phase; S3. Add the oil phase to the aqueous phase at 75°C, homogenize at 2000 rpm for 5 min, cool to 45°C, add the deep repair and anti-aging composition and preservative in sequence, stir evenly, and discharge to obtain the emulsion.

[0033] The method for preparing the emulsion in the blank application example includes the following steps: S1. Mix deionized water and thickener evenly, add humectant, heat to 75℃, and stir evenly to obtain aqueous phase; S2. Heat the emulsifier to 75°C, stir until melted, add the oil, stir evenly to obtain the oil phase; S3. Add the oil phase to the aqueous phase at 75°C, homogenize at 2000 rpm for 5 min, cool to 45°C, add the preservative, stir evenly, and discharge to obtain the emulsion.

[0034] Application Test Example 1: Skin Irritation Test Test samples: 0.025 mL of the emulsions prepared in Application Examples 1-5, Comparative Application Examples 1-10, and Blank Application Examples were taken as test samples, and a blank control group containing only distilled water was set up. Subjects: 85 participants were selected according to the subject inclusion criteria. The test sample was added into the spot tester and applied to the flexor side of the subject's forearm with hypoallergenic adhesive tape. The spot tester was removed after 24 hours. If there was any product remaining, it was gently wiped off with a tissue. Skin reactions were observed 24 hours after the spot tester was removed and recorded according to the skin reaction grading standard in the "Cosmetic Safety Technical Specifications (2015 Edition)" (see Table 6).

[0035] Table 6 Skin Reaction Grading Standards Rating levels Skin reaction 0 negative reaction 1 Suspicious reaction, only slight erythema 2 Weak positive reaction (erythema reaction): erythema, infiltration, edema, and papules may be present. 3 Strong positive reaction (herpes reaction): erythema, infiltration, edema, papules; the reaction may extend beyond the test area. 4 Extremely strong positive reaction (confluent herpes simplex reaction): obvious erythema, severe infiltration, edema, confluent herpes simplex; reaction extends beyond the test area. After testing, the lotions provided in Application Examples 1-5, Comparative Application Examples 1-10, and Blank Application Examples of the present invention all showed negative results after human patch testing, indicating that the lotions provided by the present invention are safe and non-irritating to human skin and that no adverse reactions occurred during use.

[0036] Application Test Example 2: Repair and Anti-aging Effect Test Eighty volunteers aged 18-45 were randomly divided into 16 groups of 5 people each. The lotions prepared in Application Examples 1-5, Control Application Examples 1-10 and Blank Application Examples were used as samples. The samples were applied to the face after cleansing and moisturizing in the morning and evening. One pump (about 1g) of the sample was applied evenly to the entire face each time and gently massaged until fully absorbed. Follow-up visits were conducted on day 0 and day 28 to test various indicators. On days 0 and 28, subjects did not apply any skincare products. After cleansing, they sat quietly for 30 minutes in a constant temperature and humidity room (21±1℃, 50±10%). The skin elasticity coefficient (R²), number of wrinkles, and transepidermal water loss (TEWL) value of the same area were measured using a Cutometer® skin elasticity tester, a VISIA® high-precision skin image analysis system, and a Tewameter®™ Hex transepidermal water loss tester, respectively. The improvement rate of each indicator was calculated according to the formula. R2 improvement rate = [(mean of day 28 - mean of day 0) / mean of day 0] × 100%; Wrinkle quantity improvement rate or TEWL value improvement rate = [(mean of day 0 - mean of day 28) / mean of day 0] × 100%; The results, after being averaged, are recorded in Table 7 below.

[0037] Table 7 Repairing and Soothing Effects Group R2 improvement rate / % Wrinkle reduction rate / % TEWL value improvement rate / % Blank application example 2.2 2.5 1.9 Application Example 1 34.7 35.6 23.1 Application Example 2 33.2 34.1 22.3 Application Example 3 34.0 34.9 22.8 Application Example 4 30.8 31.4 20.7 Application Example 5 32.1 32.8 21.6 Comparative Application Example 1 16.4 16.9 10.0 Comparative Application Example 2 18.5 19.2 12.2 Comparative Application Example 3 17.2 17.8 10.7 Comparative Application Example 4 19.3 19.7 12.5 Comparative Application Example 5 24.7 25.2 16.5 Comparative Application Example 6 26.4 26.8 17.9 Comparative Application Example 7 21.9 22.3 13.8 Comparative Application Example 8 23.6 24.1 15.6 Comparative Application Example 9 22.5 23.0 14.3 Comparative Application Example 10 24.2 24.6 16.1 As shown in Table 7, the emulsion prepared using the deep repair and anti-aging composition of the present invention can effectively improve skin elasticity, reduce wrinkles, and enhance the skin barrier, thus exerting good repair and anti-aging effects.

[0038] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present invention. Any indirect modifications, equivalent changes, and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A deep-repairing and anti-aging composition containing Edelweiss and Peony seed oil, characterized in that, The deep repair and anti-aging composition includes the following components: Edelweiss extract, peony seed oil, spruce extract, and desert rose leaf cell extract, wherein the weight ratio of Edelweiss extract, peony seed oil, spruce extract, and desert rose leaf cell extract is (3-6):(0.5-2):(1.5-3):(0.2-0.6).

2. The deep repair and anti-aging composition containing Edelweiss and peony seed oil according to claim 1, characterized in that, The weight ratio of the Edelweiss extract, peony seed oil, spruce extract, and desert rose leaf cell extract is (4-5):(1-1.5):(2.2-2.6):(0.3-0.4).

3. The application of the deep-repairing and anti-aging composition containing Edelweiss and peony seed oil as described in claim 1 or 2 in the preparation of skincare products, characterized in that, The skincare products include any one of toner, cream, mask, lotion, and spray, and the amount of the deep repair and anti-aging composition added is 1%-3% of the total weight of the skincare products.

4. An emulsion, characterized in that, The emulsion comprises the following raw materials by weight percentage: 1%-3% of the deep repair and anti-aging composition as described in claim 1 or 2, 5-12% of oil, 3%-10% of moisturizer, 0.05%-0.5% of thickener, 3%-5% of emulsifier, 0.05%-0.3% of preservative, and the balance being deionized water.

5. The emulsion according to claim 4, characterized in that, The oil is selected from one or more of the following: caprylic / capric triglycerides, squalane, jojoba seed oil, macadamia nut oil, olive oil, and cyclopentamethoxysiloxane.

6. The emulsion according to claim 4, characterized in that, The moisturizer is selected from one or more of glycerin, dipropylene glycol, allantoin, panthenol, trehalose, and betaine.

7. The emulsion according to claim 4, characterized in that, The thickener is selected from one or more of cetearyl alcohol, xanthan gum, carbomer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, and ammonium acryloyldimethyl taurate / VP copolymer.

8. The emulsion according to claim 4, characterized in that, The emulsifier is selected from one or more of glyceryl stearate, methyl glucose sesquistearate, PEG-20 methyl glucose sesquistearate, C12-20 alkyl glucoside, and sucrose stearate.

9. The emulsion according to claim 4, characterized in that, The preservative is selected from one or more of methylparaben, propylparaben, bis(hydroxymethyl)imidazolidinyl urea, 1,2-hexanediol, and p-hydroxyacetophenone.

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