Moisturizing and repairing cosmetic composition as well as preparation method and application thereof

Abstract

The invention provides a moisturizing and repairing cosmetic composition which comprises the following components in parts by weight: 1-20 parts of a hyaluronic acid composition, 1-15 parts of erythritol, 0.5-10 parts of Ectoine, 0.1-10 parts of a soothing and repairing composition and 0.1-3 parts of a lecithin composition, and the soothing and repairing composition comprises the following components: bisabolol and a ginger root extract. The cosmetic composition disclosed by the invention has synergistic long-acting moisturizing, soothing, repairing and skin smoothing effects, and is quick in effect taking and excellent in effect; and the cosmetic is non-irritant, can relieve the face, is not greasy, and has good skin feeling.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and in particular to a moisturizing and repairing cosmetic composition, its preparation method, and its application. Background Technology

[0002] Due to the combined effects of skin physiology and the external environment, skin dryness, barrier damage, and sensitivity are becoming increasingly prominent issues and have become one of the core problems that urgently need to be addressed in the current skincare field.

[0003] Studies have shown that with age, the content of key moisturizing and barrier-related substances (such as hyaluronic acid and ceramides) in human skin gradually decreases, and their own synthesis capacity also weakens significantly. At the same time, environmental pollution, staying up late, stress, and sun exposure can damage skin tissue, making the skin more prone to dryness and flaking, and causing skin discomfort. Researchers have investigated the causes of dry and damaged skin, and the main causes are: (1) weakened barrier due to aging, resulting in dry skin; (2) reduced synthesis of key moisturizing and barrier lipids such as ceramides and hyaluronic acid; (3) skin sensitivity caused by stress, low immunity, and environmental pollution; and (4) damage to the skin caused by medical aesthetic procedures. In order to alleviate dryness and improve fragility and repair damage, consumers have increasingly higher requirements for cosmetics.

[0004] Currently, the efficacy of most cosmetics on the market is a predictable result of mixing different raw materials. However, it's common for combining multiple cosmetic ingredients to not only fail to deliver the desired multiple effects but also to actually reduce their effectiveness. For example, in the research and sales of moisturizing and repairing cosmetics, it has been found that most of these products contain only a single moisturizing ingredient.

[0005] Currently, commercially available products generally choose one or two of the above reasons as their entry point. However, due to limitations in cost and the concentration of raw material components, the effects are generally mediocre and slow to take effect. The main reasons are as follows: Firstly, high-concentration, high-molecular-weight hyaluronic acid is difficult to absorb effectively, while low-molecular-weight hyaluronic acid, although absorbed faster, does not provide sufficient long-lasting moisturizing power. Secondly, if many other moisturizing ingredients are combined, it may irritate the skin, but low concentrations are unlikely to achieve the desired effect. Finally, the combination of active ingredients that meet multiple moisturizing needs cannot achieve soothing and repairing effects. Summary of the Invention

[0006] This invention addresses the problems existing in the prior art by providing a long-lasting moisturizing and soothing cosmetic composition, its preparation method, and its application. The cosmetic composition comprises a hyaluronic acid composition, erythritol, ectoine, a soothing and repairing composition, and a lecithin composition. The components are compounded in specific weight parts to achieve synergistic effects of long-lasting moisturizing, soothing and repairing, and refining the skin. It is fast-acting and has excellent results. The cosmetic is non-irritating, soothing and non-greasy on the face, and has a pleasant skin feel.

[0007] The first aspect of the present invention discloses a moisturizing and repairing cosmetic composition comprising the following components in parts by weight: 1-20 parts of hyaluronic acid composition, 1-15 parts of erythritol, 0.5-10 parts of ectoine, 0.1-10 parts of soothing and repairing composition, and 0.1-3 parts of lecithin composition.

[0008] By combining hyaluronic acid, erythritol, ectoine, soothing and repairing composition, and lecithin composition in specific proportions, the cosmetic composition achieves synergistic effects of long-lasting moisturizing, soothing and repairing, and refining the skin.

[0009] The hyaluronic acid composition includes the following components: sodium hyaluronate crosspolymer, sodium hyaluronate, acetylated hyaluronic acid, hydrolyzed hyaluronic acid, 1,2-pentanediol, ethylhexylglycerin, and water. The soothing and repairing composition includes the following components: bisabolol and ginger root extract. The lecithin composition includes the following components: lecithin and sodium acrylate copolymer.

[0010] In this invention, the most fundamental characteristic of hyaluronic acid is its ability to carry more than 500 times its own weight in water, making it the best moisturizing substance found in nature. The numerous hydrophilic groups on its molecular chain, such as the carboxyl and hydroxyl groups in its molecular structure, can combine with water molecules through hydrogen bonds to form a strong "hydration layer".

[0011] Erythritol can upregulate AQP3 expression, promote water transmembrane transport, and synergistically enhance the penetration of subsequent active substances. Ectoin, also known as tetrahydromethylpyrimidine carboxylic acid, can activate the heat shock protein HSP70, enhance cellular stress resistance, and reduce environmentally induced fluctuations in barrier function.

[0012] In this invention, erythritol and ectoine form a co-osmotic system, that is, erythritol forms a "water molecule bridge" through intermolecular hydrogen bonds, carrying ectoine through the particle layer and improving the targeting of the basal layer (the penetration depth was increased by 40% as confirmed by fluorescent labeling).

[0013] In this invention, bisabolol is a potent anti-inflammatory agent. It can inhibit the release of pro-inflammatory cytokines (such as TNF-α and IL-6), blocking the inflammatory response chain at its source. At the same time, it can promote intercellular communication, support the skin's own repair process, and fundamentally improve sensitivity and barrier damage caused by inflammation.

[0014] The active substances in ginger root extract include 6-gingerol, 8-gingerol, and gingerdiols, which have anti-inflammatory, antioxidant, and microcirculation-promoting effects. Ginger root extract and bisabolol can form a synergistic soothing and repairing effect. Because ginger root extract has potential irritation, it can be buffered by the calming and anti-inflammatory effects of bisabolol. The lipid solubility and retention of bisabolol can prolong the low-dose release of ginger root activity in the skin, thereby reducing irritation. Tests have shown that the composite composition with added bisabolol and ginger root extract has a significantly improved duration and stability of soothing and repairing effects compared to adding bisabolol alone.

[0015] In this invention, the combination of hyaluronic acid, erythritol-ectoine, and soothing and repairing composition is not simply an additive of moisturizing and soothing ingredients. Instead, it forms a progressive synergy through four levels: cell stress protection, inflammatory signal regulation, barrier structure repair, and hydration environment stabilization. As a result, it is significantly superior to any single or dual-component system in terms of onset speed, long-lasting effect, and barrier repair.

[0016] In addition to its moisturizing effect, the hyaluronic acid combination prolongs the residence time of other active ingredients on the skin surface by creating a skin hydration and film-forming environment, reducing irritation peaks and improving overall tolerance. Ectoin and erythritol create a low-sensitivity microenvironment by stabilizing cell hydration and stress state. On this basis, ginger root extract continuously regulates irritation and inflammatory signals, while bisabolol achieves rapid calming and barrier repair. Multiple ingredients form a progressive synergistic effect at multiple levels of cells, signals, and barriers, thereby significantly improving the soothing and repairing effect. At the same time, it also makes the required dosage of the soothing and repairing composition lower and significantly improves tolerance.

[0017] Preferably, the cosmetic composition comprises, by weight, the following components: 2-5 parts hyaluronic acid composition, 2-5 parts erythritol, 1-5 parts ectoine, 0.1-1 parts soothing and repairing composition, and 0.5-2 parts lecithin composition; The hyaluronic acid composition comprises, by weight percentage: 0.2-0.5% sodium hyaluronate crosspolymer, 0.5-1% sodium hyaluronate, 0.5-1.2% acetylated hyaluronic acid, 0.1-0.2% hydrolyzed hyaluronic acid, 3-5% 1,2-pentanediol, 0.05-0.1% ethylhexylglycerin, and the balance being water. The erythritol composition comprises, by weight percentage: 100% erythritol. The soothing and repairing composition comprises, by weight percentage: >50% bisabolol, 0.1-1% ginger root extract. The lecithin composition comprises, by weight percentage: 20-30% lecithin, 70-80% sodium acrylate copolymer.

[0018] Preferably, the ginger root extract of the present invention is prepared by a low-irritation directed alcohol-water extraction method, thereby minimizing the risk of irritation, and is compatible with components such as ectoine and erythritol, and can be directly introduced into the aqueous phase.

[0019] The preparation method of ginger root extract includes the following steps: (1) Select fresh or dried ginger root as raw material and crush it to 40-80 mesh with uniform particle size; (2) Add 30–60% ethanol by volume to it, and then stir and extract at ≤45℃ for 2–5 hours. Low-power ultrasound can be used to assist extraction. Filter and collect the filtrate. (3) Remove ethanol by vacuum concentration at a temperature of ≤45°C and a pressure of approximately -0.08 MPa to obtain a concentrated aqueous ginger root extract.

[0020] The above-mentioned aqueous ginger root extract concentrate can be used directly in cosmetic compositions or as a liposome encapsulation precursor. Alternatively, the above-mentioned aqueous ginger root extract concentrate can be further prepared into a dry powder extract.

[0021] Ginger root extract is a plant extract obtained through low-temperature alcohol-water extraction, which can reduce irritating components.

[0022] Preferably, the ginger root extract of the present invention is encapsulated by a liposome structure formed with lecithin as the main membrane material, so that the active ingredients of ginger root are stably dispersed in an aqueous system and form a slow-release, low-irritation soothing and repairing effect on the skin surface.

[0023] More preferably, the lecithin nanoliposomes encapsulate the ginger root extract and bisabolol.

[0024] Lecithin and bisabolol were dissolved in the alcohol phase to form a lipid phase. The lipid phase was then slowly added to the aqueous phase containing ginger root extract. After high-shear emulsification and high-pressure homogenization, the active ingredients of ginger root were encapsulated in the aqueous phase core of the liposomes, and bisabolol was embedded in the phospholipid bilayer, thereby obtaining a composite liposome system with a particle size of nanometers.

[0025] In the lecithin nanoliposomes used, the synergistic effect is further amplified: bisabolol is embedded in the phospholipid bilayer to stabilize the liposomes, and the ginger root activity is located in the aqueous core to achieve a sustained-release effect.

[0026] Bisabolol is a fat-soluble active substance. In formulations aimed at soothing repair and high tolerability, encapsulation with lecithin significantly improves stability compared to direct addition, making it less prone to precipitation, reducing the risk of irritation, improving tolerability, and providing sustained release with better duration. It also has significant advantages in synergistic effects, and is especially suitable for use in combination with ginger root extract, ectoine, and hyaluronic acid.

[0027] The lecithin nanoliposomes have a particle size of approximately 80-200 nm, with a bisabolol encapsulation rate of ≥80% and a ginger root extract encapsulation rate of ≥60%. The weight fraction of lecithin in the lecithin nanoliposomes is included in the weight fraction of the lecithin composition.

[0028] A second aspect of the present invention provides a method for preparing the above-described cosmetic composition, comprising the steps of: S1. Mix the raw materials according to the weight percentage, stir, and prepare hyaluronic acid composition, soothing and repairing composition and lecithin composition respectively; S2. Mix the hyaluronic acid composition with the lecithin composition and stir to obtain the first composition; S3. Mix the first composition with erythritol, ectoine and the soothing composition to obtain a cosmetic composition.

[0029] A third aspect of the present invention provides the use of the above-described cosmetic composition in the preparation of cosmetics, wherein the cosmetic composition is suitable for preparing cosmetics with long-lasting moisturizing, skin-refining and soothing repair effects.

[0030] A third aspect of the present invention provides a cosmetic product comprising the above-mentioned cosmetic composition, which has synergistic effects of long-lasting moisturizing, soothing and repairing, and refining the skin, with rapid and excellent results; the cosmetic product is non-irritating, soothing and non-greasy on the face, and has a good skin feel.

[0031] The cosmetic composition of the present invention can be applied by those skilled in the art to the preparation of cosmetics according to actual needs. Cosmetics are not limited to toners, lotions, serums, creams, ointments and masks.

[0032] Compared with existing technologies, the above technical solution has the following advantages: 1. The cosmetic composition of the present invention combines hyaluronic acid composition, erythritol, ectoine, soothing and repairing composition and lecithin composition in specific proportions to achieve synergistic effects of long-lasting moisturizing, soothing and repairing, and refining the skin.

[0033] 2. When the cosmetic composition of the present invention is applied to the preparation of cosmetics, the prepared cosmetics can promote skin hydration, effectively relieve dryness and comprehensively improve rough skin, and soothe and repair damaged skin.

[0034] 3. The formulation of each component in the cosmetic composition of the present invention is reasonable. It combines various hyaluronic acids, erythritol, ectoine, bisabolol, ginger root extract and other basic solvents, which simplifies the cosmetic manufacturing process. Moreover, the combination of the obtained hyaluronic acid composition, erythritol, soothing and repairing composition, ectoine composition and lecithin composition results in a cosmetic composition that is fast-acting, has strong all-around long-lasting moisturizing and soothing and repairing effects on the skin, and improves dry and rough skin. The skin is stable after using the cosmetic and no sensitivity problems have occurred. Attached Figure Description

[0035] Figure 1 A photograph of the facial erythema and damage improvement experiment D0 of a subject using the cosmetic composition of Example 1 of the present invention; Figure 2 for Figure 1 A photograph of subject D30; Figure 3 A photograph of the facial erythema and damage improvement experiment D0 of a subject using the cosmetic composition of Example 4 of this invention; Figure 4 for Figure 3 A photograph of subject D30; Figure 5 A photograph of the facial erythema and damage improvement experiment D0 of a subject using the cosmetic composition of Example 5 of the present invention; Figure 6 for Figure 5 A photograph of subject D30. Detailed Implementation

[0036] The advantages of the present invention will be further illustrated below with reference to the accompanying drawings and specific embodiments.

[0037] Exemplary embodiments will now be described in detail, some examples of which are illustrated in the accompanying drawings. The invention will be more readily understood by referring to the following detailed description of preferred embodiments and included examples. Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In case of any conflict, the definitions in this specification shall prevail.

[0038] As used herein, the terms “prepared from…” and “comprising” are synonymous. The terms “comprising,” “including,” “having,” “containing,” or any other variations thereof, as used herein, are intended to cover non-exclusive inclusion. For example, a composition, step, method, article, or apparatus comprising the listed elements is not necessarily limited to those elements, but may include other elements not expressly listed or elements inherent to such a composition, step, method, article, or apparatus. The conjunction “composed of…” excludes any unnamed elements, steps, or components. If used in a claim, this phrase makes the claim closed, excluding materials other than those described, except for conventional impurities associated with them. When the phrase “composed of…” appears in a clause of the body of a claim rather than immediately following it, it limits only the elements described in that clause; other elements are not excluded from the claim as a whole.

[0039] When a quantity, concentration, or other value or parameter is expressed as a range, a preferred range, or a range defined by a series of upper and lower preferred values, this should be understood as specifically disclosing all ranges formed by any pair of any upper or preferred value with any lower or preferred value, regardless of whether the range is disclosed individually. For example, when the range “1 to 5” is disclosed, the described range should be interpreted as including ranges “1 to 4”, “1 to 3”, “1 to 2”, “1 to 2 and 4 to 5”, “1 to 3 and 5”, etc. When numerical ranges are described herein, unless otherwise stated, the range is intended to include its endpoints and all integers and fractions within that range. The singular form includes plural objects of discussion unless clearly indicated by the context. “Optional” or “any” means that the matter or event described thereafter may or may not occur, and the description includes both the occurrence and non-occurrence of the event.

[0040] The approximate terms used in the specification and claims to modify quantities indicate that the invention is not limited to that specific quantity, but also includes acceptable modifications close to that quantity that do not alter the relevant essential function. Correspondingly, the use of "about," "approximately," etc., to modify a numerical value means that the invention is not limited to that precise value. In some instances, approximate terms may correspond to the precision of the instrument used to measure the value. In this application's specification and claims, scope definitions can be combined and / or interchanged, unless otherwise stated, these scopes include all subscopes contained therein. Furthermore, the indefinite articles "a" and "an" preceding elements or components of the invention are not restrictive in terms of the quantity (i.e., the number of times) required for the elements or components. Therefore, "an" or "a" should be interpreted as including one or at least one, and singular elements or components also include plural forms, unless the quantity clearly refers to the singular form.

[0041] Unless otherwise stated, the raw materials and reagents used in the embodiments of the present invention are conventionally purchased raw materials and reagents. The ginger root extract in the embodiments is prepared using the preparation method of ginger root extract described in the above-described part of the invention.

[0042] Example 1 Cosmetic composition 1, comprising the following components in the following parts by weight: According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 40 minutes to obtain cosmetic composition 1.

[0043] The obtained cosmetic composition 1 is used in the preparation of serum. The preparation method of serum includes the following steps: take the above cosmetic composition 1 and mix it with conventional cosmetic base ingredients, stir at room temperature for about 40 minutes until uniform, and obtain serum; in serum, cosmetic composition 1 accounts for 5% and conventional cosmetic base ingredients account for 95%.

[0044] The above-mentioned basic ingredients of conventional cosmetics, and the specific ingredients and their weight percentages are as follows: propylene glycol 3%, hexanediol 0.6%, succinate 0.6%, and water 90.8%.

[0045] Example 2 Cosmetic composition 2, comprising the following components in the following parts by weight: According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 40 minutes to obtain cosmetic composition 2.

[0046] Example 2 increases the weight percentage of the hyaluronic acid composition based on Example 1.

[0047] The obtained cosmetic composition 2 was used to prepare an essence. The preparation method of the essence, the basic ingredients of conventional cosmetics, and the weight percentage of each ingredient were the same as in Example 1.

[0048] Example 3 Cosmetic composition 3, comprising the following components in the following parts by weight: According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 45 minutes to obtain cosmetic composition 3.

[0049] Example 3 is based on Example 2, but with an increased weight percentage of erythritol.

[0050] The obtained cosmetic composition 3 is applied to the preparation of face cream. The preparation method of face cream includes the following steps: take the above cosmetic composition 3 and mix it with conventional cosmetic base ingredients, stir at room temperature for about 40 minutes until uniform, and obtain face cream; in face cream, cosmetic composition 3 accounts for 5% and conventional cosmetic base ingredients account for 95%.

[0051] The specific ingredients and their weight percentages for the above-mentioned basic cosmetic ingredients are as follows: Jojoba oil 5%, squalane 3%, emulsifier 3%, co-emulsifier 1%, propylene glycol 3%, hexane glycol 0.6%, chloroform 0.6%, and water 78.8%. Example 4 Cosmetic composition 4, comprising the following components in the following parts by weight: According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 45 minutes to obtain cosmetic composition 4.

[0052] Example 4 increases the weight percentage of the soothing composition based on Example 3.

[0053] The obtained cosmetic composition 4 is applied to the preparation of face cream. The preparation method of face cream includes the following steps: take the above cosmetic composition 4 and mix it with conventional cosmetic base ingredients, stir at room temperature for about 40 minutes until uniform, and obtain face cream; in face cream, cosmetic composition 4 accounts for 14.5% and conventional cosmetic base ingredients account for 85.5%.

[0054] The above-mentioned basic ingredients of conventional cosmetics, each ingredient and its weight percentage are the same as in Example 3.

[0055] Example 5 Cosmetic composition 5, comprising the following components in the following parts by weight: According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 45 minutes to obtain cosmetic composition 5.

[0056] Example 5, based on Example 3, uses a process of encapsulating ginger root extract and bisabolol with lecithin nanoliposomes, thereby increasing the weight fraction of lecithin.

[0057] The obtained cosmetic composition 5 is applied to the preparation of face cream. The preparation method of face cream includes the following steps: take the above cosmetic composition 5 and mix it with conventional cosmetic base ingredients, stir at room temperature for about 40 minutes until uniform, and obtain face cream; in face cream, cosmetic composition 5 accounts for 15% and conventional cosmetic base ingredients account for 85%.

[0058] The above-mentioned basic ingredients of conventional cosmetics, each ingredient and its weight percentage are the same as in Example 3.

[0059] Comparative Example 1 Cosmetic composition 5, comprising the following components in the following parts by weight: Unlike Example 1, the cosmetic composition contains 1% hyaluronic acid, while all other parameters are the same as in Example 1, resulting in an essence.

[0060] According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 40 minutes to obtain cosmetic composition 6.

[0061] The obtained cosmetic composition 6 is used in the preparation of an essence. The preparation method of the essence includes the following steps: mixing the above cosmetic composition 6 with conventional cosmetic base ingredients, stirring at room temperature for about 40 minutes until homogeneous, to obtain the essence; in the essence, cosmetic composition 6 accounts for 5%, and conventional cosmetic base ingredients account for 95%. The conventional cosmetic base ingredients are the same as in Example 1.

[0062] Comparative Example 2 Cosmetic composition 7, comprising the following components in the following parts by weight: Unlike Example 1, cosmetic composition 7 does not contain erythritol, but all other parameters are the same as in Example 1, resulting in an essence.

[0063] According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 40 minutes to obtain cosmetic composition 7.

[0064] The obtained cosmetic composition 7 was used in the preparation of an essence. The preparation method of the essence included the following steps: mixing the above cosmetic composition 7 with conventional cosmetic base ingredients, stirring at room temperature for about 40 minutes until homogeneous, to obtain the essence; in the essence, the cosmetic composition accounted for 9%, and the conventional cosmetic base ingredients accounted for 91%. The conventional cosmetic base ingredients were the same as in Example 1.

[0065] Comparative Example 3 Cosmetic composition 8, comprising the following components in the following parts by weight: Unlike Example 3, ectoine was not added to the components of the cosmetic composition, but all other parameters were the same as in Example 3, and a face cream was prepared.

[0066] According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 45 minutes to obtain cosmetic composition 8.

[0067] The obtained cosmetic composition 8 was applied to the preparation of a face cream. The preparation method of the face cream included the following steps: mixing the above cosmetic composition 8 with conventional cosmetic base ingredients, stirring at room temperature for about 40 minutes until uniform, to obtain a face cream; in the face cream, the cosmetic composition accounted for 4.5%, and the conventional cosmetic base ingredients accounted for 95.5%. The conventional cosmetic base ingredients were the same as in Example 3.

[0068] Comparative Example 4 Cosmetic composition 9, comprising the following components in the following parts by weight: Unlike Example 3, the soothing composition of Comparative Example 4 consisted only of bisabolol and did not contain ginger root extract. All other parameters were the same as in Example 3, and a face cream was prepared.

[0069] According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 45 minutes to obtain cosmetic composition 8.

[0070] The obtained cosmetic composition 9 was applied to the preparation of a face cream. The preparation method of the face cream included the following steps: taking the above cosmetic composition 8 and mixing it with conventional cosmetic base ingredients, stirring at room temperature for about 40 minutes until uniform, to obtain a face cream; in the face cream, the cosmetic composition accounted for 5%, and the conventional cosmetic base ingredients accounted for 95%. The conventional cosmetic base ingredients were the same as in Example 3.

[0071] Comparative Example 5 Cosmetic composition 10, comprising the following components in the following parts by weight: Unlike Example 3, cosmetic composition 10 does not contain a soothing composition, but all other parameters are the same as in Example 3, and a face cream is prepared.

[0072] According to the above weight percentages, the raw materials of each component are mixed separately and stirred at room temperature for about 45 minutes to obtain cosmetic composition 10.

[0073] The obtained cosmetic composition 10 is used in the preparation of a face cream. The preparation method of the face cream includes the following steps: taking the above cosmetic composition 10 and mixing it with conventional cosmetic base ingredients, stirring at room temperature for about 40 minutes until uniform, to obtain a face cream; in the face cream, the cosmetic composition accounts for 5%, and the conventional cosmetic base ingredients account for 95%. The conventional cosmetic base ingredients are the same as in Example 3.

[0074] Effect Test 1: Moisturizing Effect Test Subject screening and grouping were conducted as follows: Number of participants: 50 healthy female volunteers aged 25-45 years who meet the Fitzpatrick skin type III-IV were recruited.

[0075] Inclusion criteria: Mildly dry skin on the cheeks, with an initial stratum corneum moisture content (Corneometer value) between 30-40 a.u. No active skin diseases or history of allergies. Informed consent must be signed before the trial.

[0076] Grouping method: A randomized, double-blind, parallel group design was adopted. Fifty subjects were randomly divided into 10 groups of 5 each, using formulations 1 to 10, corresponding to cosmetic compositions 10 of Examples 1-5 and Comparative Examples 1-5, respectively.

[0077] Environmental requirements: All measurements were performed in a temperature and humidity controlled chamber. Environmental conditions were strictly controlled as follows: temperature 22 ± 1 °C, relative humidity 50 ± 5%.

[0078] Subject preparation room: Subjects need to sit quietly in a preparation room with the same temperature and humidity conditions to adapt before the measurement.

[0079] 1.1 Water content of the stratum corneum The moisturizing effects of the serums and creams prepared in Examples 1-5 and Comparative Examples 1-5 were evaluated by testing the stratum corneum moisture content.

[0080] The measurement methods are all based on the principle that the dielectric constant of water is much higher than that of a dry stratum corneum. The instrument indirectly calculates the skin's water content by measuring changes in the dielectric properties (such as capacitance and conductivity) of the skin surface. A higher value indicates a higher water content in the stratum corneum.

[0081] Moisturizing effects are divided into immediate effects and long-term effects. Immediate effects are measured at 15 minutes, 1 hour, and 4 hours after product application. Long-term effects are measured by having subjects use the product twice a day and return to the laboratory for measurement at weeks 1, 2, 4, and 8 (subjects need to wash their face with water and sit quietly to acclimatize before measurement).

[0082] The main measuring device used is the Corneometer® CM 825 skin moisture test probe from Courage + Khazaka, Germany. This device measures the moisture content of the stratum corneum of the skin based on the capacitance principle.

[0083] The stratum corneum moisture content was tested according to the above-described method, and the data were recorded. Table 1 shows the test results of the serums and creams prepared in Examples 1-5 and Comparative Examples 1-5 on increasing stratum corneum moisture content. Table 1 Where D0 represents day 0, i.e., the stratum corneum moisture status before the subject used the product, and au represents a relative unit.

[0084] 1.2 Transdermal water loss by TEWL TEWL stands for transepidermal water loss. It measures the amount of water that evaporates from the deeper layers of the skin through the epidermis into the external environment (measured in grams per square meter per hour). A higher TEWL value indicates that the skin loses more water and that the stratum corneum's barrier function is weaker.

[0085] Table 2 uses the reduction in water loss as a measure of the formula's moisturizing and repairing effects.

[0086] Table 2 As can be seen from the experimental results in Tables 1 and 2, the serums prepared in Examples 1-2 are more effective in moisturizing and reducing moisture loss compared to those prepared in Comparative Examples 1-2. Similarly, the face creams prepared in Examples 3-5 are significantly better than those prepared in Comparative Examples 3-5 in terms of moisturizing and reducing moisture loss.

[0087] Comparative Example 2 contained only a hyaluronic acid composition and ectoine, while Comparative Example 3 contained only a hyaluronic acid composition and erythritol; both showed the worst moisturizing effect in inhibiting moisture loss. Therefore, this invention combines ectoine and erythritol, which, when combined with hyaluronic acid, produces a significant synergistic effect in inhibiting moisture loss and providing long-lasting skin hydration.

[0088] Comparative Examples 4 and 5 showed weaker effects than Example 3, indicating that the soothing composition also has a moisturizing effect. The superiority of Comparative Example 4 over Comparative Example 5 also demonstrates that ginger root extract can produce a synergistic effect with bisabolol. Furthermore, Example 5, using lecithin nanoliposome encapsulation technology, achieved a similar effect with a smaller amount of soothing composition than Example 4, and this was achieved with the same amount used in Example 3.

[0089] Effect Test 2: Skin Barrier Function Repair Effect Test 2.1 Improves damaged and red skin Sixty women aged 40-60 were selected as subjects and divided into 6 groups of 10 each. Before the test, the subjects washed their faces and stayed in a constant temperature and humidity environment (temperature 21-23℃, humidity 55-65%) for 30 minutes. Facial photos were taken using C-CUBE as initial data. The subjects applied the corresponding essence or cream (Example 1, Comparative Example 1, Example 4, Example 5, Comparative Example 4, Comparative Example 5) to their faces twice a day for 30 consecutive days. On day 0 and day 30, facial erythema was recorded using C-CUBE after washing the face and was recorded as D0 (day 0) and D30 (day 30), respectively.

[0090] Instrument test data is expressed in RZ values, which represent the proportion of erythema. The larger the RZ value, the larger the area of ​​erythema on the skin and the more severe the skin damage.

[0091] The D0 and D30 values ​​for each group are the average values ​​of those groups. The instrument software calculates the improvement in facial erythema and damage before and after use; a higher score indicates more erythema. The test results are shown in Table 3: Table 3 contrast Figure 1 and Figure 2 , Figure 3 and Figure 4 , Figure 5 and Figure 6 In all cases, significant improvement in facial erythema and lesions can be observed.

[0092] As can be seen from the results in Table 3, Example 1 with added erythritol showed better repair and redness reduction effects compared to Comparative Example 2 without added erythritol.

[0093] Example 4, with the addition of a soothing composition, showed better repair and redness reduction compared to Comparative Example 4, which only added bisabolol. Comparative Example 4, with the addition of bisabolol alone, was superior to Comparative Example 5, which did not contain any soothing composition. Example 5, employing lecithin nanoliposome encapsulation technology, showed slightly better repair and redness reduction than Example 5, even with a smaller amount of soothing composition.

[0094] This invention rationally combines three active ingredients with repairing effects, a specific soothing active ingredient, and lecithin to obtain cosmetic compositions, serums, and creams that produce significant synergistic effects in moisturizing, soothing, strengthening the skin barrier, and reducing redness.

[0095] 2.2 Repairing and enhancing skin barrier function Participant selection: 30 participants, 14 males and 16 females, aged between 30 and 50 years.

[0096] The experimental apparatus used was hypoallergenic topical adhesive tape (3M, USA) and a Mexameter MXI8 red pigment analyzer (Courage Khazaka Electronic, Germany). The experimental materials were the face creams from Examples 3, 4, Comparative Example 3, and Comparative Example 4.

[0097] Experimental Methods: The amount of skin erythema was measured at a pre-defined test area on the forearm of the subjects using a Mexameter MX18 erythrocyte analyzer, and this amount was defined as D0 (baseline value). 0.02 mL of 3% SDS solution was precisely pipetted into the center of each test chamber and then applied to the pre-defined area on the volunteer's forearm. The test chamber was removed after 24 hours. The amount of skin erythema was measured 4 hours later and defined as 100%. Then, on days 1-3 after SDS treatment, the same amount (1.2 g) of cream from Examples 3, 4, Comparative Example 3, and Comparative Example 4 was applied to the test area on the forearm of the subjects. The amount of skin erythema was measured after 28 days.

[0098] The effects of the cosmetic compositions tested on the amount of skin erythema are shown in Table 4. Table 4 As can be seen from the results in Table 4, Example 3 with added ectoine showed better results in repairing and enhancing the skin barrier function compared to Comparative Example 3 without added ectoine.

[0099] Example 4, which added a soothing composition, showed better results in repairing and enhancing the skin barrier function compared to Comparative Example 4, which only added bisabolol.

[0100] It should be noted that the embodiments of the present invention have better implementability and are not intended to limit the present invention in any way. Any person skilled in the art may use the above-disclosed technical content to change or modify it into equivalent effective embodiments. However, any modifications or equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention shall still fall within the scope of the technical solution of the present invention.

Claims

1. A moisturizing and repairing cosmetic composition, characterized in that, The product comprises the following components in parts by weight: 1-20 parts hyaluronic acid composition, 1-15 parts erythritol, 0.5-10 parts ectoine, 0.1-10 parts soothing and repairing composition, and 0.1-3 parts lecithin composition, wherein the soothing and repairing composition comprises the components: bisabolol and ginger root extract.

2. The cosmetic composition according to claim 1, characterized in that, The composition includes, by weight, 2-5 parts hyaluronic acid composition, 2-5 parts erythritol, 1-5 parts ectoine, 0.1-1 parts soothing and repairing composition, and 0.5-2 parts lecithin composition.

3. The cosmetic composition according to claim 1, characterized in that, The soothing and repairing composition comprises, by weight percentage: >50% bisabolol and 0.1-1% ginger root extract.

4. The cosmetic composition according to claim 1, characterized in that, The hyaluronic acid composition comprises the following components: sodium hyaluronate crosspolymer, sodium hyaluronate, acetylated hyaluronic acid, hydrolyzed hyaluronic acid, 1,2-pentanediol, ethylhexylglycerin, and water; the lecithin composition comprises the following components: lecithin and sodium acrylate copolymer.

5. The cosmetic composition according to claim 1, characterized in that, The preparation method of ginger root extract includes the following steps: (1) Select fresh or dried ginger root as raw material and crush it; (2) Add 30-60% ethanol by volume to it, and then stir and extract at ≤45℃ for 2-5 hours, and filter and collect the filtrate; (3) Remove ethanol by vacuum concentration.

6. The cosmetic composition according to claim 1, characterized in that, Lecithin nanoliposomes encapsulate the ginger root extract and bisabolol.

7. The cosmetic composition according to claim 6, characterized in that, The active ingredients of ginger root are encapsulated in the aqueous core of the lecithin nanoliposome, and bisabolol is embedded in the phospholipid bilayer.

8. The method for preparing the cosmetic composition according to any one of claims 1-7, characterized in that, Including the following steps: S1. Mix the raw materials according to the weight percentage, stir, and prepare hyaluronic acid composition, soothing and repairing composition and lecithin composition respectively; S2. Mix the hyaluronic acid composition with the lecithin composition and stir to obtain the first composition; S3. Mix the first composition with erythritol, ectoine and the soothing composition to obtain a cosmetic composition.

9. The application of a cosmetic composition in the preparation of cosmetics, characterized in that, The cosmetic composition is the cosmetic composition according to any one of claims 1-7.

10. A cosmetic product comprising the cosmetic composition according to any one of claims 1-7.

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