Rapid dyeing mechanism for specimen slicing

By using flexible filter paper to locally fix the edges of the slides and employing a non-immersion drip staining process, the problems of tissue breakage and staining solution contamination caused by rigid filter screens are solved, achieving efficient and clean staining of specimen slides and ensuring the accuracy of test results.

CN121954598APending Publication Date: 2026-05-01RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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Patent Information

Application Number
CN202610212312.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-02-13
Publication Date
2026-05-01

AI Technical Summary

Technical Problem

In existing technologies, specimen sections are prone to tissue rupture and staining contamination due to mechanical pressure from rigid filters during staining, which affects the accuracy of test results.

Method used

Flexible filter paper is used to locally adhere and fix the edges of the sections. Combined with a non-immersion drip staining process, the adsorption force of the moist filter paper is used to achieve dynamic fixation of the sections, avoiding mechanical damage to the tissue and contamination of the dye solution by the hard filter.

Benefits of technology

It improves staining efficiency and the accuracy of test results, avoids tissue rupture and dye contamination, and achieves efficient and clean staining without chemical binders.

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Abstract

The invention provides a rapid dyeing mechanism for specimen sections, which comprises a transportation assembly, a clamping assembly and an auxiliary fitting assembly, and the transportation assembly is provided with a dyeing station; the clamping assembly comprises two liftable clamping plates, and when a glass slide is conveyed to a dyeing station, the clamping plates descend to clamp and fix the glass slide from the two sides; the auxiliary laminating assembly is arranged on the clamping plate, the auxiliary laminating assembly comprises a strip-shaped carrier, a driving part and a pressing block, the strip-shaped carrier is provided with a separable filter paper sheet, and the driving part drives the pressing block to move in the direction close to the glass slide so as to press down the filter paper sheet from the strip-shaped carrier; and the filter paper sheet is adhered to the edge of the section and the surface of the glass slide, so that the mechanical damage of the edge of the rigid mesh to the expanded tissue is avoided.
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Description

A rapid staining mechanism for specimen sections Technical Field

[0001] This invention relates to the field of specimen slide preparation, and more particularly to a rapid staining mechanism for specimen slides. Background Technology

[0002] Staining is the simplest and most effective method for observing cells. Through staining, cells can be colored and contrasted sharply with the background, allowing tissue structures to be observed more clearly.

[0003] To prevent tissue sections from detaching from the slide, existing techniques primarily employ the following methods: 1. Using highly viscous chemical adhesives. This method may cause tissue cell degeneration or tearing, affecting the accuracy of the test results.

[0004] 2. Use mechanical fixing devices. For example, a filter screen is placed over the slices to physically restrict their movement.

[0005] While using a filter for fixation avoids the influence of chemical adhesives, it has the following technical drawbacks: During staining, the tissue sections absorb the staining solution and swell. The edges of the filter mesh covering these sections exert uneven mechanical pressure on the swollen tissue. Especially in areas of fragile tissue, this pressure can easily lead to tissue rupture, producing debris that contaminates the staining solution, affecting its reuse and potentially interfering with subsequent testing results. Furthermore, the process of removing the filter after fixation may cause secondary damage to the stained tissue. Summary of the Invention

[0006] The purpose of this invention is to address the shortcomings of existing technologies by providing a rapid staining mechanism for specimen sections.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a rapid staining mechanism for specimen slides, comprising: a transport assembly having a staining station; a clamping assembly including two liftable clamps, wherein when a slide is transported to the staining station, the clamps descend to clamp and fix the slide from both sides; and an auxiliary bonding assembly disposed on the clamps, comprising a strip carrier, a driving member, and a pressing block, wherein a separable filter paper is disposed on the strip carrier, and the driving member drives the pressing block to move toward the slide to press the filter paper off the strip carrier and attach the filter paper to the edge of the slide and the surface of the slide.

[0008] In a preferred embodiment, the auxiliary bonding assembly further includes: a bracket disposed on the inner side of the clamping plate; a plurality of rollers rotatably disposed on the bracket, the strip carrier being tensioned and sleeved on the rollers; and a driving member fixed to the bracket.

[0009] In a preferred embodiment, the auxiliary bonding assembly further includes: an upper roller, which is rotatably disposed on the outside of the clamping plate; a lower roller, which is rotatably disposed on the outside of the clamping plate; the first end of the strip carrier is wound around the upper roller, and the end of the strip carrier is wound around the lower roller after passing over the roller.

[0010] In a preferred embodiment, the strip carrier is provided with a plurality of storage sections, which are arranged along the length of the strip carrier, and each storage section carries a filter paper sheet.

[0011] In a preferred embodiment, the transport component includes: a turntable; a first transmission belt disposed on the turntable, the first transmission belt having a dyeing station on it; and a second transmission belt; the turntable is rotatable and drives the first transmission belt to dock with the second transmission belt.

[0012] In a preferred embodiment, the device further includes: a body, wherein the body has a dyeing chamber and a liquid storage chamber that are separated from each other; a transport assembly, a clamping assembly and an auxiliary bonding assembly are disposed in the dyeing chamber; and a plurality of dye tanks are placed in the liquid storage chamber.

[0013] In a preferred embodiment, the system further includes: a staining assembly disposed above the staining station for adding staining solution to a slide located on the staining station; and a staining solution extraction assembly disposed in the storage chamber for extracting staining solution from the fuel tank and transporting it to the staining assembly.

[0014] In a preferred embodiment, the dyeing assembly includes: a dyeing cantilever fixed to the machine body; a dyeing drive seat slidably disposed on the dyeing cantilever; a liquid pump mounted on the dyeing drive seat; and a dropper connected to the liquid pump.

[0015] In a preferred embodiment, the dye extraction assembly includes: an extraction drive seat slidably disposed on the machine body; an extraction cantilever connected to the extraction drive seat; an extraction electric push rod mounted on the extraction cantilever; a liquid aspiration probe connected to the telescopic end of the extraction electric push rod; and a flexible tubing connected to the liquid aspiration probe and the dropper.

[0016] In a preferred embodiment, a camera is also included, which is mounted on the clamp and has its field of view facing the dyeing station.

[0017] In a preferred embodiment, the top of the body is provided with an openable cover.

[0018] Compared with existing technologies, this technical solution has the following advantages: Traditional immersion staining relies on a rigid filter mesh to physically press the slides. After the slides absorb water and swell, they are easily cut by the edges of the mesh, producing debris that contaminates the staining solution. In this invention, at the moment of staining, a pressure block is used to press a flexible filter paper sheet only onto the edge of the slide and the surface of the glass slide. The moistened filter paper sheet is fixed by the liquid's adsorption force, which avoids direct mechanical damage to the swollen tissue from the rigid mesh and eliminates staining solution contamination caused by tissue damage, significantly improving the integrity of the stained sample and the accuracy of the test results.

[0019] This invention integrates automated transmission, intelligent clamping, dynamic fixation, precise liquid supply, and process monitoring. From slide loading to unloading after staining, the entire process requires no manual intervention. Attached Figure Description

[0020] Figure 1 is a structural schematic diagram of the rapid staining mechanism for specimen sections according to the present invention; Figure 2 is an assembly schematic diagram of the clamping plate and auxiliary bonding component according to the present invention; Figure 3 is a structural schematic diagram of the auxiliary bonding component according to the present invention; Figure 4 is an assembly schematic diagram of the body, transport component, clamping component, staining component and staining solution extraction component according to the present invention; Figure 5 is an enlarged schematic diagram of A in Figure 4; Figure 6 is a structural schematic diagram of the staining solution extraction component according to the present invention.

[0021] In the diagram: 100 Transport assembly, 100a Dyeing station, 110 First transmission belt, 120 Turntable, 130 Second conveyor belt, 200 Clamping assembly, 210 Clamping plate, 211 Short plate, 211a Positioning protrusion, 212 Long plate, 212a Perforation, 220 Electric push rod, 230 Support plate, 300 Auxiliary bonding assembly, 310 Strip carrier, 311 Filter paper, 320 Drive component, 330 Pressure block, 340 Bracket, 341 Upper support rod, 342 Lower support rod, 343 Middle support rod, 350 Roller, 361 Upper roll 362 Lower winding cylinder, 362a Storage unit, 400 Staining assembly, 410 Staining cantilever, 420 Staining drive seat, 430 Liquid pump, 440 Dropper, 500 Dye extraction assembly, 510 Extraction drive seat, 520 Extraction cantilever, 530 Extraction electric actuator, 540 Liquid aspiration probe, 550 Flexible tubing, 560 Hanging ring, 600 Body, 601 Staining chamber, 602 Liquid storage chamber, 602a Dye tank, 602b Slide rail, 700 Camera, 810 Cover, 1000 Glass slide, 2000 Section. Detailed Implementation

[0022] The following description is intended to disclose the present invention and enable those skilled in the art to implement it. The preferred embodiments described below are merely examples, and other obvious variations will occur to those skilled in the art. The basic principles of the invention defined in the following description can be applied to other embodiments, modifications, improvements, equivalents, and other technical solutions that do not depart from the spirit and scope of the invention.

[0023] Please refer to Figures 1 to 3. An embodiment of the present invention provides a rapid staining mechanism for specimen slides, comprising: a transport assembly 100, wherein the transport assembly 100 is provided with a staining station 100a; a clamping assembly 200, wherein the clamping assembly 200 includes two liftable clamping plates 210, which lower to clamp and fix the slide 1000 from both sides when the slide 1000 is transported to the staining station 100a; and an auxiliary bonding assembly 300, wherein the auxiliary bonding assembly... The bonding component 300 is disposed on the clamping plate 210. The auxiliary bonding component 300 includes a strip carrier 310, a driving member 320 and a pressing block 330. The strip carrier 310 is provided with a separable filter paper sheet 311. The driving member 320 drives the pressing block 330 to move towards the glass slide 1000, so as to press the filter paper sheet 311 off the strip carrier 310 and make the filter paper sheet 311 adhere to the edge of the slice 2000 and the surface of the glass slide 1000.

[0024] Flexible filter paper 311 is used instead of traditional rigid filter mesh, avoiding mechanical damage to the expanded tissue caused by the edges of the rigid mesh. Furthermore, the filter paper 311 is only partially adhered and fixed to the edges of the section 2000, not completely covering the section surface, allowing the tissue to expand uniformly. The entire process is automated, improving the consistency of staining efficiency.

[0025] As shown in Figures 1 and 4, the transport assembly 100 includes: a turntable 120; a first transmission belt 110, which is disposed on the turntable 120 and has a dyeing station 100a; and a second transmission belt 130. The turntable 120 is rotatable and drives the first transmission belt 110 to dock with the second transmission belt 130.

[0026] The first conveyor belt 110 is fixedly installed on the upper surface of the turntable 120, and its conveying direction is arranged radially along the turntable 120. The dyeing station 100a is located in the section of the first conveyor belt 110 near the center of the turntable 120.

[0027] The feed end of the second conveyor belt 130 extends to the outside of the machine body 600 to receive the glass slides 1000 to be stained; its discharge end is opposite to the edge of the turntable 120 to realize the material transfer with the first conveyor belt 110.

[0028] The turntable 120 is driven by a drive motor fixed to the bottom of the staining chamber 601 and can rotate in the horizontal plane. When the turntable 120 rotates to the first angle, the conveying direction of the first conveyor belt 110 is aligned with the conveying direction of the second conveyor belt 130. At this time, the slide 1000 can be transferred from the second conveyor belt 130 to the first conveyor belt 110 and conveyed along the first conveyor belt 110 to the staining station 100a. Subsequently, the turntable 120 rotates to the second angle to reset, so that the conveying direction of the first conveyor belt 110 is perpendicular to the conveying direction of the second conveyor belt 130.

[0029] As shown in Figures 1 and 2, the clamping assembly 200 includes two symmetrically arranged, independently liftable L-shaped clamping plates 210. Each clamping plate 210 is composed of a short plate 211 and a long plate 212 that are perpendicularly connected to each other, and is used to fit and clamp two adjacent edges of a rectangular glass slide 1000.

[0030] The clamping assembly 200 also includes two support plates 230 and two electric push rods 220. One end of each support plate 230 is fixedly connected to the inner wall of the staining chamber 601, and the other end is connected to the corresponding clamping plate 210 via an electric push rod 220. Each electric push rod 220 can independently drive the corresponding clamping plate 210 to move up and down in the vertical direction to clamp or release the glass slide 1000.

[0031] Furthermore, the electric push rod 220 is connected at the corner between the short plate 211 and the long plate 212 to ensure that the clamping plate 210 is subjected to balanced force and moves smoothly during lifting and clamping, thus avoiding structural deformation or insecure clamping of the glass slide due to force eccentricity.

[0032] As shown in Figures 1 and 2, the upper surface of the first conveyor belt 110 is recessed relative to the upper surface of the turntable 120, forming a conveying channel with a depth slightly less than the thickness of the glass slide 1000. When the clamping plate 210 descends to the working position, the long plate 212 abuts against the upper surface of the turntable 120. The bottom end of the short plate 211 is provided with a downwardly extending positioning protrusion 211a. When the clamping plate 210 descends to the working position, the bottom surface of the positioning protrusion 211a abuts against the upper surface of the first conveyor belt 110.

[0033] At this time, the slide 1000 is in a positioned state, with its edge matching the inner surface of the long plate 212 and the short plate 211 of the clamp 210, thus being confined within the staining station 100a enclosed by the two clamps 210.

[0034] As shown in Figure 1, the rapid staining mechanism for specimen sections also includes a camera 700, which is mounted on the short plate 211 of the clamping plate 210, and the field of view of the camera 700 is directed toward the staining station 100a.

[0035] When the clamping plate 210 descends to the working position and the positioning protrusion 211a abuts against the upper surface of the first conveyor belt 110, the lens of the camera 700 is positioned directly above the glass slide 1000, with its field of view fully covering the staining area. During the staining process, the camera 700 captures images of the staining solution dripping onto the slide surface in real time to capture the amount of staining solution used during the dripping process, thus avoiding waste caused by excessive use of staining solution.

[0036] As shown in Figures 1 to 3, the auxiliary bonding component 300 includes a strip carrier 310, a driving component 320, a pressure block 330, a bracket 340, and multiple rollers 350.

[0037] The bracket 340 is fixedly installed on the inner side of the long plate 212 of the clamping plate 210. The bracket 340 includes two upper support rods 341, two lower support rods 342, and a middle support rod 343 connecting the corresponding upper and lower support rods. A roller 350 is pivotally connected between the opposite ends of the two upper support rods, and a roller 350 is pivotally connected between the opposite ends of the two lower support rods. The middle support rod enhances the rigidity and stability of the overall bracket.

[0038] The outer surface of the strip carrier 310 is provided with a plurality of separable flexible filter paper sheets 311 at equal intervals along its circumference.

[0039] The drive unit 320 is fixedly installed inside the central support rod or frame of the bracket 340, located between the upper and lower rollers. The pressure block 330 is connected to the output end of the drive unit 320. When the strip carrier 310 is rotated in a controlled manner, causing one of the filter paper pieces 311 to move directly opposite the edge of the slide 2000 on the staining station, the drive unit 320 is activated, driving the pressure block 330 to move downwards in a direction perpendicular to the slide 1000. The downward pressure of the pressure block 330 peels the filter paper piece 311 from the bearing surface of the strip carrier 310 and presses it tightly against the exposed edge of the slide 2000 and the adjacent surface of the slide 1000. The moist staining solution then firmly adheres the filter paper piece 311, thereby achieving flexible local fixation of the slide edge and preventing it from falling off in subsequent staining processes.

[0040] As shown in Figures 1 and 2, the auxiliary bonding assembly 300 further includes: an upper drum 361, rotatably disposed on the outside of the clamping plate 210; and a lower drum 362, rotatably disposed on the outside of the clamping plate 210. The first end of the strip carrier 310 is wound around the upper drum 361, and the end of the strip carrier 310 is wound around the lower drum 362 after passing over the roller 350. The roller 350 may be a driven wheel. The upper drum 361 and the lower drum 362 are driven by independent small motors to achieve synchronous winding and unwinding.

[0041] The clamping plate 210 has a perforation 212a on its long plate 212 through which the strip carrier 310 passes. During operation, the upper drum 361 releases the strip carrier 310 in a controlled manner, while the lower drum 362 winds up and recycles the used (i.e., after the filter paper 311 has been peeled off) section of the strip carrier 310 in a controlled manner, thereby realizing automatic feeding and recycling of the strip carrier 310 and ensuring that a brand new filter paper 311 is used for each pressing operation.

[0042] As shown in Figure 1, there are two auxiliary bonding components 300, and each auxiliary bonding component 300 is connected to the long plate 212 of one of the clamping plates 210. The two auxiliary bonding components 300 are arranged at intervals along the length direction of the glass slide 1000, respectively corresponding to the two opposite edges of the slice 2000 along the length direction, so as to realize the synchronous flexible pressing and fixing of the two edges of the slice 2000.

[0043] As shown in Figure 2, the strip carrier 310 can be made of a flexible and dimensionally stable polymer film (such as polyester PET, polyimide PI) or a paper-based strip. The filter paper 311 is preferably a laboratory-grade qualitative filter paper with high adsorption capacity and uniform fiber structure.

[0044] The strip carrier 310 is a long strip with a head and an end. Multiple receiving portions 362a for accommodating filter paper sheets 311 are evenly spaced along its length. The receiving portions 362a can be designed as grooves or through-holes. The filter paper sheets 311 are temporarily fixed within the receiving portions 362a by a peelable pressure-sensitive adhesive layer or a water-soluble adhesive. This connection method ensures the stability of the filter paper sheets 311 during transport and positioning, and also allows them to detach smoothly from the strip carrier 310 and transfer to the surface of the glass slide when sufficient downward pressure is applied by the pressure block 330.

[0045] As shown in Figure 4, the rapid staining mechanism for specimen sections further includes: a body 600, the body 600 having a staining chamber 601 inside; a transport component 100, a clamping component 200, and an auxiliary bonding component 300 disposed within the staining chamber 601.

[0046] As shown in Figures 4 and 5, the rapid staining mechanism for specimen sections further includes a staining component 400, which is located inside the staining chamber 601 and above the staining station 100a, for adding staining solution to the slide 1000 located at the staining station 100a.

[0047] Our institution employs a non-immersion drip staining process, combined with an auxiliary bonding component 300 for dynamic, localized, flexible fixation of the slide edges, forming its core operating mode. During staining, the staining solution dripped by the staining component 400 simultaneously wets the slide and the filter paper 311 pressed against the slide edges and the slide surface. The wetted filter paper 311 generates adsorption force through capillary action and liquid surface tension, thus firmly adhering to the slide surface and achieving physical anchoring of the slide edges. This fixation method eliminates the need for external chemical adhesives throughout the process, completely avoiding potential contamination or interference from additional chemical substances to the slide samples, achieving efficient, clean, and mechanically damage-free staining treatment.

[0048] Specifically, the dyeing assembly 400 includes: a dyeing cantilever 410 fixed to the machine body 600; a dyeing drive seat 420 slidably disposed on the dyeing cantilever 410; a liquid pump 430 mounted on the dyeing drive seat 420; and a dropper 440 connected to the liquid pump 430.

[0049] The dyeing drive seat 420 is slidably mounted on the dyeing cantilever 410 via a linear guide or slider mechanism, allowing it to move horizontally along the length of the cantilever. The liquid pump 430 (preferably a miniature precision metering pump) is fixedly mounted on the dyeing drive seat 420. The inlet end of the dropper 440 is connected to the outlet end of the liquid pump 430, with its outlet end pointing vertically downwards toward the dyeing station 100a.

[0050] During operation, the staining drive seat 420 is moved along the staining cantilever 410, precisely positioning the dropper 440 directly above the target section 2000. Subsequently, the liquid pump 430 is activated, drawing up the staining solution and delivering it to the dropper 440. Under the combined action of gravity and the pressure of the liquid pump 430, the staining solution drips from the outlet of the dropper 440 onto the surface of the section 2000 at a controllable flow rate, achieving precise staining of the target area.

[0051] As shown in Figure 4, the interior of the machine body 600 is divided into an independent dyeing chamber 601 and a liquid storage chamber 602 by a partition. The liquid storage chamber 602 is equipped with multiple dye tanks 602a for storing different types or batches of dye solutions.

[0052] The rapid staining mechanism for specimen sections further includes a staining solution extraction component 500 disposed within the storage chamber 602. The staining solution extraction component 500 is used to precisely extract staining solution from a designated dye tank 602a according to the staining process requirements, and to transport the staining solution through a fluid pipeline to the staining component 400 located within the staining chamber 601 to supply the required staining solution.

[0053] The dye extraction assembly 500 includes: an extraction drive seat 510, which is slidably mounted on the body 600; an extraction cantilever 520, which is connected to the extraction drive seat 510; an extraction electric push rod 530, which is mounted on the extraction cantilever 520; a liquid aspiration probe 540, which is connected to the telescopic end of the extraction electric push rod 530; and a flexible tubing 550, which is connected to the liquid aspiration probe 540 and the dropper 440.

[0054] The body 600 is provided with a slide rail 602b arranged along the length of the liquid storage chamber 602. The extraction drive seat 510 is slidably connected to the slide rail 602b and can reciprocate along the slide rail 602b under the drive of a drive mechanism (such as a servo motor and a synchronous belt) to cover the upper position of all dye tanks 602a in the liquid storage chamber.

[0055] The extraction cantilever 520 is a multi-joint robotic arm structure, with its base hinged to the extraction drive seat 510, allowing it to extend, retract, and rotate in the horizontal plane. The extraction electric actuator 530 is vertically mounted on the end effector of the extraction cantilever 520. The liquid aspiration probe 540 is connected to the telescopic end of the extraction electric actuator 530 and can be driven by the electric actuator for precise vertical lifting and lowering.

[0056] One end of the flexible tubing 550 is connected to the aspiration probe 540, and the other end passes through a sealed interface on the chamber partition, communicating with the dropper 440 in the staining chamber 601 or the upstream liquid pump 430, forming a complete closed staining solution delivery path. Furthermore, a hanging ring 560 is provided at the end of the extraction cantilever 520, through which the flexible tubing 550 passes.

[0057] This multi-degree-of-freedom design enables the aspiration probe 540 to be precisely positioned directly above any dye tank 602a and perform an aspiration operation under the coordinated linear motion of the extraction drive seat 510 and the articulation of the extraction cantilever 520, thereby achieving automatic switching and supply of multiple dye solutions.

[0058] As shown in Figure 4, the top of the machine body 600 is provided with an openable and closable cover 810. The cover 810 covers the staining chamber 601 and the liquid storage chamber 602 respectively.

[0059] The method of using the rapid staining mechanism for specimen sections is as follows: Step 1: Loading and positioning. Start the equipment and the control system issues a command. The turntable 120 rotates to the first angle, aligning the conveying directions of the first conveyor belt 110 and the second conveyor belt 130.

[0060] The second conveyor belt 130 starts, smoothly transporting the glass slide 1000 to the edge of the turntable 120 and transferring it to the first conveyor belt 110.

[0061] The first conveyor belt 110 is started, which transports the glass slide 1000 radially inward until it reaches the predetermined staining station 100a.

[0062] Turntable 120 rotates to the second angle reset, so that the conveying direction of the first conveyor belt 110 is perpendicular to the second conveyor belt 130.

[0063] Step 2: The electric push rods 220 that hold the two clamping plates 210 move synchronously or sequentially, driving the L-shaped clamping plates 210 to descend.

[0064] The bottom surface of the long plate 212 of the clamping plate 210 contacts the upper surface of the turntable 120, and the positioning protrusion 211a at the bottom of the short plate 211 abuts against the upper surface of the first conveyor belt 110, thereby precisely limiting the descent stroke.

[0065] Two clamping plates 210 surround the glass slide 1000 from both sides, and the inner sides of the long plate 212 and the short plate 211 respectively contact the edge of the glass slide, thus completing the reliable positioning and clamping of the glass slide 1000 and preventing it from moving in subsequent steps.

[0066] Step 3: Drop dyeing and co-fixation. The upper roll 361 releases the strip carrier 310, and the lower roll 362 simultaneously winds it, causing the strip carrier 310 to move until an unused filter paper sheet 311 is positioned directly opposite one edge of the slice 2000. The auxiliary bonding assembly 300 on the other side performs the same operation to achieve double-sided positioning.

[0067] The staining unit 400 and the staining solution extraction unit 500 are operational, and the dropper 440 begins to drip the staining solution onto the surface of the slide 2000 at a preset flow rate and pattern (such as continuous or intermittent dripping). While the staining solution wets the tissue slide, it also rapidly wets the filter paper 311 that has just been pressed on.

[0068] At the same time, the camera 700 installed on the clamp 210 is activated, and the camera 700 collects images of the dye solution dripping onto the surface of the slice in real time to capture the amount of dye solution used during the dripping process.

[0069] After staining is completed, the clamping assembly 200 and other components are reset. Additionally, the automatic feeding of the glass slide 1000 can be achieved through the reverse rotation of the turntable 120 and the reverse transmission of the first conveyor belt 110 and the second conveyor belt 130.

[0070] The moistened filter paper 311 generates a strong adsorption force through capillary action and liquid surface tension, firmly anchoring itself to the surface of the glass slide. This provides effective flexible restraint on the edges of the slides throughout the staining process, preventing them from falling off or curling due to liquid flow impact or tissue expansion.

[0071] The embodiments described above are only used to illustrate the technical ideas and features of the present invention. Their purpose is to enable those skilled in the art to understand the content of the present invention and implement it accordingly. The scope of patent application of the present invention should not be limited by these embodiments. That is, all equivalent changes or modifications made in accordance with the spirit disclosed in the present invention still fall within the patent scope of the present invention.

Claims

1. A rapid staining mechanism for specimen sections, characterized in that, include: A transport assembly (100) is provided with a staining station (100a); a clamping assembly (200) includes two liftable clamps (210), which lower to clamp and fix the slide (1000) from both sides when the slide (1000) is transported to the staining station (100a); and an auxiliary bonding assembly (300) is provided on the clamps (210). The bonding aid assembly (300) includes a strip carrier (310), a drive member (320), and a pressing block (330). The strip carrier (310) is provided with a separable filter paper sheet (311). The drive member (320) drives the pressing block (330) to move toward the glass slide (1000) to press the filter paper sheet (311) off the strip carrier (310) and make the filter paper sheet (311) adhere to the edge of the slice (2000) and the surface of the glass slide (1000).

2. The rapid staining mechanism for specimen sections as described in claim 1, characterized in that, The auxiliary bonding assembly (300) further includes: a bracket (340) disposed on the inner side of the clamping plate (210); a plurality of rollers (350) rotatably disposed on the bracket (340), and the strip carrier (310) being tensionedly sleeved on the rollers (350); and the driving member (320) fixed on the bracket (340).

3. The rapid staining mechanism for specimen sections as described in claim 2, characterized in that, The auxiliary bonding assembly (300) further includes: an upper roller (361) rotatably disposed on the outside of the clamping plate (210); a lower roller (362) rotatably disposed on the outside of the clamping plate (210); the first end of the strip carrier (310) is wound around the upper roller (361), and the end of the strip carrier (310) is wound around the lower roller (362) after passing over the roller (350).

4. The rapid staining mechanism for specimen sections as described in claim 1, characterized in that, The strip carrier (310) is provided with a plurality of storage sections (362a), which are arranged along the length direction of the strip carrier (310), and each storage section (362a) carries a filter paper sheet (311).

5. The rapid staining mechanism for specimen sections as described in claim 1, characterized in that, The transport assembly (100) includes: a turntable (120); a first transmission belt (110) disposed on the turntable (120), and a dyeing station (100a) disposed on the first transmission belt (110); a second transmission belt (130); the turntable (120) is rotatable and drives the first transmission belt (110) to dock with the second transmission belt (130).

6. The rapid staining mechanism for specimen sections as described in claim 1, characterized in that, Also includes: The body (600) has a dyeing chamber (601) and a liquid storage chamber (602) that are separated from each other; a transport assembly (100), a clamping assembly (200) and an auxiliary bonding assembly (300) are disposed in the dyeing chamber (601); and a plurality of dye tanks (602a) are placed in the liquid storage chamber (602).

7. The rapid staining mechanism for specimen sections as described in claim 6, characterized in that, Also includes: A staining assembly (400) is disposed above the staining station (100a) and is used to add staining solution to the slide (1000) located on the staining station (100a); a staining solution extraction assembly (500) is disposed in the liquid storage chamber (602) and is used to extract staining solution from the fuel tank (602a) and transport it to the staining assembly (400).

8. The rapid staining mechanism for specimen sections as described in claim 7, characterized in that, The dyeing assembly (400) includes: a dyeing cantilever (410) fixed to the body (600); a dyeing drive seat (420) slidably disposed on the dyeing cantilever (410); a liquid pump (430) mounted on the dyeing drive seat (420); and a dropper (440) connected to the liquid pump (430).

9. The rapid staining mechanism for specimen sections as described in claim 8, characterized in that, The dye extraction assembly (500) includes: an extraction drive seat (510) slidably disposed on the body (600); an extraction cantilever (520) connected to the extraction drive seat (510); an extraction electric push rod (530) mounted on the extraction cantilever (520); a liquid aspiration probe (540) connected to the telescopic end of the extraction electric push rod (530); and a flexible tubing (550) connected to the liquid aspiration probe (540) and the dropper (440).

10. The rapid staining mechanism for specimen sections as described in claim 1, characterized in that, It also includes a camera (700) mounted on the clamp (210) with its field of view facing the dyeing station (100a).