Radix astragali, mulberry leaf and rehmannia composite powder and preparation method thereof

Abstract

The invention belongs to the technical field of astragalus mongholicus, mulberry leaf and rehmannia composite powder, and particularly relates to astragalus mongholicus, mulberry leaf and rehmannia composite powder and a preparation method thereof.The preparation method comprises the following steps that astragalus mongholicus, frosted mulberry leaf and rehmannia are washed, cut / smashed and pretreated; mixing the pretreated main materials, adding purified water and mixed enzyme for enzymolysis, and heating for inactivation after enzymolysis; performing vacuum low-temperature drying on the mixture after enzymolysis, and controlling the water content; carrying out superfine grinding on the dried material, adding functional auxiliary materials, and uniformly mixing; and performing irradiation sterilization by adopting 60Co-gamma rays, and then performing vacuum packaging to obtain a finished product.

Description

Technical Field

[0001] This invention belongs to the technical field of compound powder of Astragalus membranaceus, mulberry leaf and Rehmannia glutinosa, and particularly relates to a compound powder of Astragalus membranaceus, mulberry leaf and Rehmannia glutinosa and its preparation method. Background Technology

[0002] Astragalus, mulberry leaves, and rehmannia are all commonly used raw materials listed in the "List of Food and Medicine with the Same Origin". Each of them contains clearly defined active ingredients, such as astragaloside A and astragalus polysaccharides in astragalus, 1-deoxynojirimycin and flavonoids in mulberry leaves, and catalpol and verbascoside in rehmannia. These components respectively endow the raw materials with the effects of enhancing immunity, assisting in regulating blood sugar, and nourishing yin, providing a raw material basis for the development of compound products. However, current compound products made from Astragalus membranaceus, mulberry leaves, and Rehmannia glutinosa have significant shortcomings in their preparation processes and product design. Most use simple pulverization and mixing or traditional decoction and drying processes. The former fails to effectively destroy the cell walls of the raw materials, resulting in the inability to fully release active ingredients such as astragaloside A, DNJ, and catalpol, leading to low bioavailability. The latter easily damages some heat-sensitive components during high-temperature decoction, further reducing efficacy. At the same time, the bitter taste of Rehmannia glutinosa and the grassy taste of mulberry leaves are not effectively improved, resulting in poor palatability of the mixed product and affecting consumer acceptance. In addition, existing products are mostly designed for single functions and have not optimized their formulas for the health needs of different groups such as ordinary adults, people with high blood sugar, middle-aged and elderly people with low immunity, and people with sensitive intestines. They cannot meet personalized health needs and limit the applicability and market competitiveness of the products. Summary of the Invention

[0003] The purpose of this invention is to address the aforementioned technical problems by providing a compound powder of Astragalus membranaceus, mulberry leaves, and Rehmannia glutinosa, and its preparation method.

[0004] In view of this, the present invention provides a compound powder of Astragalus membranaceus, mulberry leaves and Rehmannia glutinosa, the compound powder being composed of main ingredients and functional excipients, the main ingredients including Astragalus membranaceus, mulberry leaves after frost and Rehmannia glutinosa.

[0005] A method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa, the preparation method comprising the following steps:

[0006] Astragalus membranaceus, frost-covered mulberry leaves, and Rehmannia glutinosa were washed, cut / crushed, and pre-treated respectively.

[0007] The pretreated main materials are mixed, purified water and mixed enzymes are added for enzymatic hydrolysis, and then the enzymes are heated to inactivate them.

[0008] The mixture after enzymatic hydrolysis is dried under vacuum at low temperature to control the moisture content;

[0009] After the dried material is ultra-finely pulverized, functional excipients are added and mixed evenly.

[0010] The product is sterilized by 60Co-γ ray irradiation and then vacuum packaged to obtain the finished product.

[0011] Preferably, the main ingredients are: 30-50 parts Astragalus membranaceus, 20-40 parts mulberry leaves after frost, and 30-40 parts Rehmannia glutinosa; the Rehmannia glutinosa is either processed Rehmannia glutinosa or raw Rehmannia glutinosa, wherein processed Rehmannia glutinosa is selected for the general adult population, the middle-aged and elderly population, and the population with portable and instant dissolution needs, while raw Rehmannia glutinosa is selected for the population with high blood sugar and the population with sensitive intestines.

[0012] Preferably, the raw material pretreatment in step one is as follows: Astragalus membranaceus: Select 3-5 year old Mongolian Astragalus membranaceus, remove fibrous roots and impurities, cut into thin slices 0.5-1cm thick, wash and pre-dry in a 45℃ forced-air drying oven until the moisture content is ≤15%;

[0013] Mulberry leaves after frost: Remove petioles and yellow leaves, crush into 10-20 mesh coarse powder, soak in 80℃ purified water for 10 minutes and then drain.

[0014] Rehmannia root: After removing impurities, cut into 1cm square pieces, soak in 5% licorice water for 5 minutes, and then drain.

[0015] Preferably, the specific parameters for the directional enzymatic hydrolysis in step two are as follows: add 10-15 times the amount of purified water according to the total weight of the main material, adjust the pH of the system to 4.5-5.5, add a mixed enzyme, which includes cellulase and pectinase, wherein the amount of cellulase added is 0.3-0.5% and the amount of pectinase added is 0.2-0.3%; control the enzymatic hydrolysis temperature at 40-50℃, and the enzymatic hydrolysis time is 1.5-2.5h; after the enzymatic hydrolysis is completed, raise the temperature to 90℃ and keep it for 10min to inactivate the enzyme activity.

[0016] Preferably, the vacuum low-temperature drying parameters in step three are: vacuum degree ≤ -0.09MPa, drying temperature 50-60℃, and drying until the material moisture content ≤ 5%.

[0017] Preferably, the fineness of the ultrafine grinding in step four is 150-200 mesh; the auxiliary materials are mixed using a three-dimensional mixer, with a mixing time of 15-20 min and a mixing speed of 15-20 r / min.

[0018] Preferably, the functional excipients are selected from one or more of the following combinations by weight:

[0019] Basic health supplement combination: 6-10 parts maltodextrin and 0.08-0.12 parts steviol glycosides;

[0020] Sugar-control combination: 8-12 parts erythritol and 4-6 parts resistant dextrin;

[0021] Immune-boosting combination: 1.5-2.5 parts of wolfberry polysaccharide and 5-7 parts of isomaltooligosaccharide;

[0022] Gut health care combination: 10-14 parts fructooligosaccharides and 4-6 parts inulin;

[0023] Portable instant combination: 6-8 parts β-cyclodextrin and 0.04-0.06 parts sucralose.

[0024] Preferably, the dose of 60Co-γ ray irradiation sterilization in step five is 5-8 kGy; the vacuum packaging specification is 8-15 g / bag, and the packaging material is food-grade aluminum-plastic composite film.

[0025] Preferred excipient combinations for different population groups are as follows:

[0026] For people with high blood sugar: Use a combination of blood sugar control ingredients, and increase the proportion of frost-covered mulberry leaves in the main ingredient to 35-40 parts by weight;

[0027] For middle-aged and elderly people with weakened immunity: use immune-enhancing excipients, and increase the weight percentage of Astragalus membranaceus in the main ingredient to 45-50 parts;

[0028] For people with sensitive intestines / constipation: Use intestinal care combination supplements, and increase the proportion of Rehmannia glutinosa in the main ingredient to 38-40 parts by weight;

[0029] For office workers / business travelers: It uses portable and instant compound excipients, and the ultra-fine grinding fineness is improved to 190-200 mesh.

[0030] The beneficial effects of this invention are:

[0031] By selecting 3-5 year old Mongolian Astragalus membranaceus, mulberry leaves after frost, and raw / processed Rehmannia glutinosa as the main ingredients, combined with targeted enzymatic hydrolysis, vacuum low-temperature drying, and 150-200 mesh ultrafine pulverization processes, the dissolution rate and retention rate of effective components are significantly improved. Among them, the dissolution rate of astragaloside A is ≥89.7%, the dissolution rate of DNJ is ≥89.7%, and the dissolution rate of catalpol is ≥90.5%. Furthermore, functional excipients are adapted to meet the needs of different groups of people, so as to achieve targeted optimization of efficacy.

[0032] Meanwhile, the bitterness of Rehmannia glutinosa is neutralized by soaking it in 5% licorice water, and the taste is improved by using natural sweeteners such as steviol glycosides, resulting in a taste score of ≥7.8. The product is sterilized by 5-8kGy 60Co-γ irradiation with no chemical residue, and the 8-15g / bag vacuum packaging takes into account both portability and freshness. Differentiated formulas are designed for different needs such as sugar control, intestinal care, and convenient and quick dissolution, effectively solving the problems of low utilization rate of effective ingredients, poor taste, and single function of traditional compound powders, and taking into account efficacy, palatability and practicality. Attached Figure Description

[0033] Figure 1 This is a flowchart of the workflow of the present invention. Detailed Implementation

[0034] The technical solutions of the embodiments of this application will be clearly described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this application. All other embodiments obtained by those skilled in the art based on the embodiments of this application are within the scope of protection of this application.

[0035] It should be noted that all directional and positional terms used in this invention, such as "up," "down," "left," "right," "front," "back," "vertical," "horizontal," "inner," "outer," "top," "lower," "lateral," "longitudinal," and "center," are only used to explain the relative positional relationships and connections between components in a specific state (as shown in the accompanying drawings). They are merely for the convenience of describing the invention and do not require the invention to be constructed and operated in a specific orientation; therefore, they should not be construed as limitations on the invention. Furthermore, descriptions involving "first," "second," etc., are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated.

[0036] In the description of this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal communication between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0037] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0038] Example 1: Basic health care compound powder (for the general adult population);

[0039] Raw material ratio (parts by weight): Main ingredients: Astragalus membranaceus 40 parts, mulberry leaves after frost 25 parts, Rehmannia glutinosa 35 parts;

[0040] Excipients: 8 parts maltodextrin (to improve taste and solubility), 0.1 parts steviol glycosides (natural sweetener).

[0041] Preparation steps; Astragalus pretreatment: 3-year-old Mongolian Astragalus, cut into 0.5cm thin slices, washed and pre-dried at 45℃ to a moisture content of 12%;

[0042] Mulberry leaf pretreatment: After frost, mulberry leaves are crushed into 15-mesh coarse powder, soaked in 80℃ water for 10 minutes, and drained.

[0043] Rehmannia glutinosa pretreatment: Cut prepared Rehmannia glutinosa into 1cm pieces, soak in 5% licorice water for 5 minutes, and drain.

[0044] Enzymatic hydrolysis: Mix the main ingredients, add 12 times the amount of purified water, adjust the pH to 5.0, add 0.4% cellulase and 0.25% pectinase, hydrolyze at 45℃ for 2 hours, and inactivate at 90℃ for 10 minutes;

[0045] Drying: under vacuum of -0.095 MPa, dry at 55°C until the moisture content is 4%;

[0046] Grinding and mixing: Grind into 180 mesh, add auxiliary materials, and mix in three dimensions for 18 minutes;

[0047] Sterilization and packaging: 6kGy irradiation sterilization, 10g / bag vacuum packaging.

[0048] Performance testing; Astragaloside A content: ≥0.8mg / g, dissolution rate 92.3%;

[0049] DNJ content: ≥0.35mg / g, dissolution rate 90.5%;

[0050] Catasyl alcohol content: ≥0.5mg / g, dissolution rate 91.2%;

[0051] Taste rating: 8.5 (sweet and mellow, with no obvious bitterness).

[0052] Example 2: Blood sugar control compound powder (for people with high blood sugar)

[0053] Ingredient ratio (parts by weight): Main ingredients: Astragalus membranaceus 30 parts, mulberry leaves after frost 40 parts (to increase DNJ content), Rehmannia glutinosa 30 parts (Rehmannia glutinosa clears heat and is suitable for people with high blood sugar).

[0054] Excipients: 10 parts erythritol (zero calories, does not raise blood sugar), 5 parts resistant dextrin (delays carbohydrate absorption).

[0055] Preparation steps: Astragalus pretreatment: 4-year-old Mongolian Astragalus, cut into 0.8cm thin slices, pre-dry at 45℃ until moisture content is 10%;

[0056] Mulberry leaf pretreatment: After frost, mulberry leaves are crushed into 10-mesh coarse powder, soaked in 80℃ water for 10 minutes, and drained.

[0057] Rehmannia glutinosa pretreatment: Cut raw Rehmannia glutinosa into 1cm pieces, soak in 5% licorice water for 5 minutes, and drain.

[0058] Enzymatic hydrolysis: Mix the main ingredients, add 15 times the amount of purified water, adjust the pH to 4.8, add 0.5% cellulase and 0.3% pectinase, hydrolyze at 48℃ for 2.5h, and inactivate at 90℃ for 10min;

[0059] Drying: under vacuum of -0.098 MPa, at 52°C, until the moisture content is 3.5%;

[0060] Grinding and mixing: Grind into 200 mesh, add auxiliary materials, and mix in three dimensions for 20 minutes;

[0061] Sterilization and packaging: 8kGy irradiation sterilization, 15g / bag vacuum packaging (single dose adapted to the needs of people controlling blood sugar).

[0062] Performance testing showed that the astragaloside A content was ≥0.6 mg / g, with a dissolution rate of 94.1%.

[0063] DNJ content: ≥0.6mg / g, dissolution rate 95.3% (significantly higher than the basic version);

[0064] Catasyl alcohol content: ≥0.45mg / g, dissolution rate 93.8%;

[0065] Taste rating: 7.8 (slightly sweet, no bitterness, meets the low-sugar needs of people controlling their blood sugar).

[0066] Example 3: Immune-enhancing compound powder (for middle-aged and elderly people with weakened immunity)

[0067] Ingredient ratio (parts by weight): Main ingredients: Astragalus membranaceus 50 parts (to increase the content of Astragalus membranaceus polysaccharides and strengthen immunity), mulberry leaves after frost 20 parts, Rehmannia glutinosa 30 parts;

[0068] Excipients: 2 parts of wolfberry polysaccharide (to enhance immunity in synergistic effect with astragalus), 6 parts of isomaltooligosaccharide (to improve intestinal absorption in middle-aged and elderly people).

[0069] Preparation steps: Astragalus pretreatment: 5-year-old Mongolian Astragalus, cut into 1cm thin slices, pre-dry at 45℃ until the moisture content is 13%;

[0070] Mulberry leaf pretreatment: After frost, mulberry leaves are crushed into 20-mesh coarse powder, soaked in 80℃ water for 10 minutes, and drained.

[0071] Rehmannia glutinosa pretreatment: Cut prepared Rehmannia glutinosa into 1cm pieces, soak in 5% licorice water for 5 minutes, and drain.

[0072] Enzymatic hydrolysis: Mix the main ingredients, add 13 times the amount of purified water, adjust the pH to 5.2, add 0.45% cellulase and 0.2% pectinase, hydrolyze at 42℃ for 2.2h, and inactivate at 90℃ for 10min;

[0073] Drying: under vacuum of -0.092 MPa, at 58°C, until the moisture content is 4.5%;

[0074] Grinding and mixing: Grind into 160 mesh, add wolfberry polysaccharide and isomaltooligosaccharide, and mix in three dimensions for 16 minutes;

[0075] Sterilization and packaging: 7kGy irradiation sterilization, 12g / bag vacuum packaging (suitable for single consumption by middle-aged and elderly people).

[0076] Performance testing showed that the astragaloside A content was ≥1.1 mg / g, with a dissolution rate of 93.5%.

[0077] Astragalus polysaccharide content: ≥8.5% (significantly higher than other examples);

[0078] DNJ content: ≥0.28mg / g, dissolution rate 89.7%;

[0079] Taste rating: 8.2 (rich and slightly sweet, suitable for middle-aged and elderly palates).

[0080] Example 4: Intestinal care compound powder (for people with sensitive intestines and constipation)

[0081] Ingredient ratio (parts by weight): Main ingredients: Astragalus membranaceus 35 parts, mulberry leaves after frost 25 parts, Rehmannia glutinosa 40 parts (Rehmannia glutinosa nourishes yin and moistens dryness, and helps improve constipation);

[0082] Excipients: 12 parts fructooligosaccharides (prebiotics, promotes the growth of beneficial bacteria in the gut), 5 parts inulin (increases dietary fiber and improves intestinal motility).

[0083] Preparation steps; Astragalus pretreatment: 3-year-old Mongolian Astragalus, cut into 0.6cm thin slices, pre-dry at 45℃ until moisture content is 11%;

[0084] Mulberry leaf pretreatment: After frost, mulberry leaves are crushed into 15-mesh coarse powder, soaked in 80℃ water for 10 minutes, and drained.

[0085] Rehmannia glutinosa pretreatment: Cut raw Rehmannia glutinosa into 1cm pieces, soak in 5% licorice water for 5 minutes, and drain.

[0086] Enzymatic hydrolysis: Mix the main ingredients, add 14 times the amount of purified water, adjust the pH to 4.6, add 0.35% cellulase and 0.25% pectinase, hydrolyze at 46℃ for 1.8h, and inactivate at 90℃ for 10min;

[0087] Drying: under vacuum of -0.096 MPa, at 54°C, until the moisture content is 3.8%;

[0088] Grinding and mixing: Grind into 190 mesh (fineer particle size, reducing intestinal irritation), add excipients, and mix in three dimensions for 19 minutes;

[0089] Sterilization and packaging: 5kGy irradiation sterilization, 15g / bag vacuum packaging (single dose meets intestinal care needs).

[0090] Performance testing showed that the astragaloside A content was ≥0.7 mg / g, with a dissolution rate of 91.8%.

[0091] Catastrophin content: ≥0.6mg / g, dissolution rate 94.5%;

[0092] Total dietary fiber content: ≥15% (provided with auxiliary materials and raw materials);

[0093] Taste rating: 8.0 (sweet and smooth, with no harshness).

[0094] Example 5: Portable instant compound powder (for office workers and business travelers)

[0095] Raw material ratio (parts by weight): Main ingredients: Astragalus membranaceus 38 parts, mulberry leaves after frost 27 parts, Rehmannia glutinosa 35 parts;

[0096] Excipients: 7 parts β-cyclodextrin (to improve solubility and mask off-flavors), 0.05 parts sucralose (a high-intensity sweetener, used in small quantities).

[0097] Preparation steps; Astragalus pretreatment: 3-year-old Mongolian Astragalus membranaceus, cut into 0.5cm thin slices, pre-dry at 45℃ until moisture content is 12%;

[0098] Mulberry leaf pretreatment: After frost, mulberry leaves are crushed into 15-mesh coarse powder, soaked in 80℃ water for 10 minutes, and drained.

[0099] Rehmannia glutinosa pretreatment: Cut prepared Rehmannia glutinosa into 1cm pieces, soak in 5% licorice water for 5 minutes, and drain.

[0100] Enzymatic hydrolysis: Mix the main ingredients, add 12 times the amount of purified water, adjust the pH to 5.0, add 0.4% cellulase and 0.25% pectinase, hydrolyze at 45℃ for 2 hours, and inactivate at 90℃ for 10 minutes;

[0101] Drying: under vacuum of -0.095 MPa, dry at 56°C until the moisture content is 4%;

[0102] Grinding and mixing: Grind into 200 mesh (extremely fine powder, quick-dissolving and no sedimentation), add auxiliary materials, and mix in three dimensions for 17 minutes;

[0103] Sterilization and packaging: 6kGy irradiation sterilization, 8g / bag vacuum packaging (small dose, portable and easy to prepare).

[0104] Performance testing; Astragaloside A content: ≥0.75mg / g, dissolution rate 92.7%;

[0105] Instant solubility: Dissolves completely within 30 seconds when mixed with 80℃ water, without any precipitate;

[0106] Taste rating: 8.8 (Sweet and refreshing, easy to prepare).

[0107] The embodiments of this application have been described above with reference to the accompanying drawings. Unless otherwise specified, the embodiments and features in the embodiments of this application can be combined with each other. This application is not limited to the specific embodiments described above. The specific embodiments described above are merely illustrative and not restrictive. Those skilled in the art can make many other forms under the guidance of this application without departing from the spirit and scope of the claims, and all of these forms are within the protection scope of this application.

Claims

1. A compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa, characterized in that: The compound powder is composed of main ingredients and functional auxiliary ingredients, the main ingredients including Astragalus membranaceus, mulberry leaves after frost, and Rehmannia glutinosa.

2. A method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa, based on the compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa as described in claim 1, characterized in that: The preparation method includes the following steps: Astragalus membranaceus, frost-covered mulberry leaves, and Rehmannia glutinosa were washed, cut / crushed, and pre-treated respectively. The pretreated main materials are mixed, purified water and mixed enzymes are added for enzymatic hydrolysis, and then the enzymes are heated to inactivate them. The mixture after enzymatic hydrolysis is dried under vacuum at low temperature to control the moisture content; After the dried material is ultra-finely pulverized, functional excipients are added and mixed evenly. The product is sterilized by 60Co-γ ray irradiation and then vacuum packaged to obtain the finished product.

3. The method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa according to claim 2, characterized in that: The main ingredients, by weight, are: 30-50 parts Astragalus membranaceus, 20-40 parts Frost-covered Mulberry Leaf, and 30-40 parts Rehmannia glutinosa. The Rehmannia glutinosa is either processed or raw. Processed Rehmannia glutinosa is selected for the general adult population, the middle-aged and elderly population, and the population with portable and instant dissolution needs, while raw Rehmannia glutinosa is selected for the population with high blood sugar and the population with sensitive intestines.

4. The method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa according to claim 3, characterized in that: The specific pretreatment of raw materials in step one is as follows: Astragalus membranaceus: Select 3-5 year old Mongolian Astragalus membranaceus, remove fibrous roots and impurities, cut into thin slices 0.5-1cm thick, wash and pre-dry in a 45℃ forced-air drying oven until the moisture content is ≤15%; Mulberry leaves after frost: Remove petioles and yellow leaves, crush into 10-20 mesh coarse powder, soak in 80℃ purified water for 10 minutes and then drain. Rehmannia root: After removing impurities, cut into 1cm square pieces, soak in 5% licorice water for 5 minutes, and then drain.

5. The method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa according to claim 4, characterized in that: The specific parameters for the targeted enzymatic hydrolysis in step two are as follows: add 10-15 times the amount of purified water according to the total weight of the main material, adjust the pH of the system to 4.5-5.5, add a mixed enzyme, which includes cellulase and pectinase, wherein the amount of cellulase added is 0.3-0.5% and the amount of pectinase added is 0.2-0.3%; control the enzymatic hydrolysis temperature at 40-50℃, and the enzymatic hydrolysis time is 1.5-2.5h; after the enzymatic hydrolysis is completed, raise the temperature to 90℃ and keep it for 10min to inactivate the enzyme activity.

6. The method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa according to claim 5, characterized in that: The vacuum low-temperature drying parameters in step three are: vacuum degree ≤ -0.09MPa, drying temperature 50-60℃, and drying until the material moisture content ≤ 5%.

7. The method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa according to claim 6, characterized in that: The fineness of the ultrafine grinding in step four is 150-200 mesh; the auxiliary materials are mixed using a three-dimensional mixer, with a mixing time of 15-20 min and a mixing speed of 15-20 r / min.

8. The method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa according to claim 7, characterized in that: The functional excipients are selected from one or more of the following combinations by weight: Basic health supplement combination: 6-10 parts maltodextrin and 0.08-0.12 parts steviol glycosides; Sugar-control combination: 8-12 parts erythritol and 4-6 parts resistant dextrin; Immune-boosting combination: 1.5-2.5 parts of wolfberry polysaccharide and 5-7 parts of isomaltooligosaccharide; Gut health care combination: 10-14 parts fructooligosaccharides and 4-6 parts inulin; Portable instant combination: 6-8 parts β-cyclodextrin and 0.04-0.06 parts sucralose.

9. The method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa according to claim 8, characterized in that: The dose of 60Co-γ ray irradiation sterilization in step five is 5-8 kGy; the vacuum packaging specification is 8-15 g / bag, and the packaging material is food-grade aluminum-plastic composite film.

10. The method for preparing a compound powder of Astragalus membranaceus, mulberry leaf, and Rehmannia glutinosa according to claim 9, characterized in that: Suitable formulations of excipients for different population groups are as follows: For people with high blood sugar: Use a combination of blood sugar control ingredients, and increase the proportion of frost-covered mulberry leaves in the main ingredient to 35-40 parts by weight; For middle-aged and elderly people with weakened immunity: use immune-enhancing excipients, and increase the weight percentage of Astragalus membranaceus in the main ingredient to 45-50 parts; For people with sensitive intestines / constipation: Use intestinal care combination supplements, and increase the proportion of Rehmannia glutinosa in the main ingredient to 38-40 parts by weight; For office workers / business travelers: It uses portable and instant compound excipients, and the ultra-fine grinding fineness is improved to 190-200 mesh.

Images