Nutritional supplement for nourishing heart and cerebral vessels

Abstract

The invention discloses a full-peptide compound preparation for nourishing heart and cerebral vessels. The full-peptide compound preparation comprises a core layer and an outer coating, the core layer contains Yang tonifying and Yang recuperating decoction source small molecule peptide and modern bioactive components, and the outer layer is a moisture-proof, slow-release or enteric coating. The preparation is stable in structure and good in absorption and utilization effect, is suitable for the fields of functional foods, health foods, special diets and the like, and has a good industrialization prospect.

Description

Technical Field

[0001] This invention belongs to the technical fields of health food, functional food, special dietary food and related pharmaceuticals, specifically relating to a cardiovascular and cerebrovascular care composition based on the compounding of small molecule peptides of traditional Chinese medicine and modern bioactive ingredients. Background Technology

[0002] Cardiovascular and cerebrovascular health problems have become a significant factor affecting population health. Currently, most commercially available related products are based on single ingredients or simple compound formulations, and traditional Chinese medicine raw materials are mostly used in the form of traditional extracts, which have problems such as limited absorption and utilization rates and lack of prominent synergistic effects.

[0003] To further improve the stability and bioavailability of products and enrich the selection of cardiovascular and cerebrovascular health products, it is necessary to provide a compound composition that is scientifically formulated, highly absorbed, and has a wider range of applications. Summary of the Invention

[0004] The purpose of this invention is to provide a fully peptided Chinese and Western medicine compound composition for cardiovascular and cerebrovascular health care, which has the characteristics of synergistic effects of components, high absorption efficiency, and good stability, and can meet the application needs of functional foods, health foods and other fields.

[0005] The present invention adopts the following technical solution:

[0006] A peptide compound composition for cardiovascular and cerebrovascular health maintenance, comprising:

[0007] (1) Small molecule active peptides derived from Buyang Huanwu Decoction, selected from at least one of Astragalus peptide, Angelica peptide, Ligusticum chuanxiong peptide, Paeonia lactiflora peptide, Carthamus tinctorius peptide, Prunus persica peptide, and Pheretima aspergillum peptide;

[0008] (2) Selected from at least one of hirudin, nattokinase, coenzyme Q10, PQQ, spermidine, and nomenolide.

[0009] In some formulations, the peptides derived from Buyang Huanwu Decoction contain two or more types.

[0010] In some formulations, the peptides derived from the Buyang Huanwu Decoction are all seven peptides: Astragalus peptide, Angelica sinensis peptide, Ligusticum chuanxiong peptide, Paeonia lactiflora peptide, Carthamus tinctorius peptide, Prunus persica peptide, and Pheretima aspergillum peptide.

[0011] Some formulations further include at least one of the following: sea cucumber peptide, collagen peptide, ginkgo peptide, tanshinone peptide, and red yeast rice peptide.

[0012] By weight percentage:

[0013] The total peptide content of Buyang Huanwu Decoction is 10% to 100%, of which Astragalus peptide content is 30% to 80%.

[0014] The total content of component (2) is 0.01% to 10%.

[0015] The present invention also provides a method for preparing the composition, comprising one or more of the following: extraction of traditional Chinese medicine, compound enzymatic hydrolysis, membrane separation and purification, low temperature concentration, nano-dispersion, microencapsulation, and drying, wherein a three-layer coating process may be selected.

[0016] The present invention also provides the application of the composition in the preparation of functional foods, health foods, special diets, and pharmaceuticals, which can be used to assist in regulating blood lipids, improving blood rheological properties, maintaining vascular endothelial function, improving microcirculation, protecting the myocardium, promoting rehabilitation after cerebral infarction and stroke, and delaying vascular aging.

[0017] Beneficial effects:

[0018] By employing the whole-peptide technology of traditional Chinese medicine, the absorption and utilization efficiency of effective ingredients is significantly improved;

[0019] Traditional Chinese medicine peptides are scientifically combined with modern bioactive components, resulting in synergistic effects across multiple targets.

[0020] The formula has good stability, and the preparation process is mature and controllable, making it suitable for industrial production.

[0021] It has a wide range of applications and can be used in functional foods, health foods, special diets and related pharmaceuticals. Detailed implementation method:

[0022] Example 1

[0023] Astragalus peptide 50%, Angelica peptide 5%, Earthworm peptide 5%, Coenzyme Q10 2%, excipients up to 100%.

[0024] Example 2

[0025] Astragalus peptide 40%, Angelica peptide 4%, Ligusticum chuanxiong peptide 4%, Paeonia lactiflora peptide 3%, Carthamus tinctorius peptide 3%, Prunus persica peptide 3%, Pheretima aspergillum peptide 5%, PQQ 0.2%, spermidine 0.3%, Nominol 0.5%, excipients up to 100%.

[0026] Example 3

[0027] Astragalus peptide 45%, earthworm peptide 6%, hirudin 3%, coenzyme Q10 2%, PQQ 0.2%, excipients up to 100%.

Claims

1. A peptide compound composition for cardiovascular and cerebrovascular health maintenance, characterized in that, include: (1) Small molecule active peptides derived from Buyang Huanwu Decoction, selected from at least one of Astragalus peptide, Angelica peptide, Ligusticum chuanxiong peptide, Paeonia lactiflora peptide, Carthamus tinctorius peptide, Prunus persica peptide, and Pheretima aspergillum peptide; (2) Selected from at least one of hirudin, nattokinase, coenzyme Q10, PQQ, spermidine, and nomenolide.

2. The composition according to claim 1, characterized in that, The peptides derived from the Buyang Huanwu Decoction contain two or more types.

3. The composition according to claim 1, characterized in that, The peptides derived from the Buyang Huanwu Decoction are all seven types: Astragalus peptide, Angelica sinensis peptide, Ligusticum chuanxiong peptide, Paeonia lactiflora peptide, Carthamus tinctorius peptide, Prunus persica peptide, and Pheretima aspergillum peptide.

4. The composition according to claim 1, characterized in that, It also contains at least one of the following: sea cucumber peptide, collagen peptide, ginkgo peptide, tanshinone peptide, and red yeast rice peptide.

5. The composition according to claim 1, characterized in that, By mass percentage: the total peptide content of Buyang Huanwu Decoction is 10% to 100%, of which Astragalus peptide content is 30% to 80%.

6. The composition according to claim 1, characterized in that, The total content of component (2) is 0.01% to 10%.

7. A method for preparing the composition according to any one of claims 1-6, characterized in that, include: One or more of the following methods are used: extraction of traditional Chinese medicine, compound enzymatic hydrolysis, membrane separation and purification, low temperature concentration, nano-dispersion, microencapsulation, liposome encapsulation, and drying. Optional features include a three-layer coating process.

8. The use of the composition according to any one of claims 1-6 in the preparation of functional foods, health foods, special diets, and pharmaceuticals; the uses include assisting in the regulation of blood lipids, improving blood rheological properties, maintaining vascular endothelial function, improving microcirculation, protecting the myocardium, rehabilitation of sequelae of cerebral infarction and stroke, and delaying vascular aging.