Plant starch soft capsule and preparation method thereof

Abstract

The present application belongs to the technical field of capsule preparation, and relates to a plant starch soft capsule and a preparation method thereof. The plant starch soft capsule is composed of hydroxypropyl starch, carrageenan, psyllium seed gum, sodium alginate, sodium hyaluronate and meglumine. The preparation method comprises the steps of raw material pretreatment, mixing and gel preparation, vacuum degassing, soft capsule forming and drying. Through innovative raw material ratio and preparation process, the soft capsule has excellent weather resistance, can adapt to transportation and storage under extreme temperature, and is mainly made of plant-derived raw materials, so that the fishy smell caused by gelatin is eliminated, and the use comfort and market acceptance are improved. The plant starch soft capsule can be applied to the field of cosmetics and used as a carrier of active ingredients.

Description

Technical Field

[0001] This invention belongs to the field of capsule formulation technology, specifically relating to a plant starch soft capsule and its preparation method. Background Technology

[0002] The information disclosed in this background section is intended only to enhance understanding of the overall background of the invention and is not necessarily to be construed as an admission or in any way implying that such information constitutes prior art known to those skilled in the art.

[0003] Soft capsules are widely used as an important packaging form in pharmaceuticals, food, and cosmetics, primarily for encapsulating various active ingredients. Currently, gelatin remains the mainstream raw material for commercially available soft capsules. However, as an animal-derived material, gelatin presents several significant challenges.

[0004] From a weather resistance perspective, gelatin soft capsules have poor weather resistance. During transportation, if exposed to high temperatures, the soft capsules may soften, deform, or even stick together; while at low temperatures, they may become brittle and easily break. For example, in the hot summer, when the temperature inside the transport vehicle exceeds 40°C, the physical form of the gelatin soft capsules may change, seriously affecting product quality. Furthermore, in the cold winter, especially in northern regions where outdoor temperatures often drop below -10°C, the brittleness of gelatin soft capsules increases significantly. They are easily broken during handling, posing a significant challenge to product transportation and storage, and presenting a high transportation risk.

[0005] In terms of odor, gelatin itself has a certain fishy smell, which gives soft capsules made from gelatin an unpleasant fishy odor. This odor is released after the product is opened, greatly affecting the consumer experience. In particular, for some people who are more sensitive to smells, such as children and pregnant women, this fishy odor may cause discomfort or even nausea, thus reducing the product's market acceptance.

[0006] Chinese Patent Publication No. CN113121889A discloses a starch film-forming composition and its application in plant-based soft capsules. Specifically, the starch film-forming composition comprises 10-35 wt% hydroxypropyl starch, 8-25 wt% cross-linked starch, 10-30 wt% plasticizer, and 20-50 wt% water. It can be combined with commonly used soft capsule excipients and prepared into plant-based starch soft capsules using a traditional soft capsule manufacturing process (ingredient preparation-gelling-capsulation-drying). Chinese Patent Publication No. CN119632945A discloses a method for preparing a composite soft capsule shell containing plant starch. The composite soft capsule shell, by weight percentage, comprises 15-30% gelatin, 5-20% modified plant starch, 1-15% composite plant gum, 1-10% dopamine-grafted pullulan, 10-30% plasticizer, and 25-45% solvent. To address the aforementioned issues with gelatin soft capsules, research has been conducted on plant starch soft capsules, as described in the aforementioned patent. However, existing technologies still fall short in improving weather resistance, making it difficult to meet market demand for high-quality soft capsule products. Summary of the Invention

[0007] This invention aims to solve the problems of poor weather resistance in existing gelatin soft capsules, and provides a plant starch soft capsule and its preparation method. Based on plant-derived raw materials, this invention's plant starch soft capsule significantly improves the weather resistance of the soft capsules through innovative formulation and preparation processes, meeting the market demand for high-quality soft capsule products.

[0008] The plant starch soft capsules of the present invention comprise the following components in parts by weight:

[0009] Hydroxypropyl starch 55-75 parts, carrageenan 20-35 parts, psyllium husk gum 2-8 parts, sodium alginate 1-5 parts, sodium hyaluronate 0.5-2 parts, meglumine 0.5-2 parts.

[0010] The preferred formulation is as follows: 65 parts hydroxypropyl starch, 30 parts carrageenan, 5 parts psyllium husk gum, 3 parts sodium alginate, 1.5 parts sodium hyaluronate, and 1 part meglumine. This formulation, through the synergistic effect of its components, can construct a stable colloidal network structure, improving the weather resistance and physical properties of the soft capsules.

[0011] The preparation method of the plant starch soft capsules of the present invention includes the following steps:

[0012] (1) Raw material pretreatment: Hydroxypropyl starch and carrageenan are crushed and sieved respectively; plantain seed gum is placed in 30-40℃ warm water at 8-12 times its weight and left to swell for 1-1.5 hours. Sodium hyaluronate and meglumine are added, and the plantain seed gum is obtained by a staged hydration process of "stirring at 50-60 rpm for 20-40 minutes → stirring at 80-100 rpm for 1-1.5 hours → stirring at 50-60 rpm for 1-2 hours".

[0013] (2) Mixing and preparing the gel: Dissolve hydroxypropyl starch in 6-8 times its weight of purified water at 60-70℃, add psyllium husk gum mixture, carrageenan and sodium alginate in sequence, control the stirring speed at different stages (100-150 rpm → 150-200 rpm), and stir until a uniform colloidal solution is formed.

[0014] (3) Vacuum degassing: Degas for 20-25 minutes under vacuum conditions of -0.08 to -0.09 MPa.

[0015] (4) Soft capsule molding: The soft capsule is formed using a rotary press at a temperature of 40-50℃, a pressure of 0.5-1.5MPa, and a mold speed of 2-4 revolutions / minute.

[0016] (5) Drying: Dry at 25-30℃ and 30%-40% relative humidity until the moisture content is 8%-12%.

[0017] Compared with the prior art, the technical advantages of the present invention are as follows:

[0018] (1) Excellent weather resistance: Through the synergistic effect of psyllium husk gum, sodium hyaluronate and meglumine in the formula and the staged hydration process, the plant starch soft capsules of the present invention can withstand high temperature of 75℃ (no deformation or oil leakage after 24 hours) and low temperature of -28℃ (no cracking and little change in hardness after 24 hours of recovery to room temperature), and can adapt to extreme temperature transportation and storage environments in different regions and seasons.

[0019] (2) No fishy smell: The plant starch soft capsules of the present invention use plant starch and plant gum as the main raw materials, completely replacing gelatin, eliminating the fishy smell of gelatin from the source, improving consumer comfort and product market acceptance.

[0020] (3) High process stability: The plant starch soft capsules of the present invention utilize a staged hydration process to ensure that the raw materials are fully swollen and dispersed, and the constructed colloidal network structure is stable. Combined with vacuum degassing, precise molding and drying parameters, soft capsule products with uniform performance can be mass-produced.

[0021] (4) Wide range of applications: The plant starch soft capsules of the present invention are applicable to the cosmetics field and can be used as carriers for repair essence, sun protection ingredients, anti-wrinkle active ingredients, etc., effectively protecting the stability of the contents and extending the shelf life of the product. Attached Figure Description

[0022] Figure 1 Weather resistance of plant starch soft capsules in groups lacking psyllium husk gum, sodium hyaluronate, and meglumine. Detailed Implementation

[0023] To make the objectives and technical solutions of this invention clearer, the following embodiments are provided for further explanation. However, the scope of protection of this invention is not limited to these embodiments; the embodiments are merely for illustrative purposes. Those skilled in the art should understand that any changes or equivalent substitutions that do not depart from the concept of this invention are included within the scope of protection of this invention.

[0024] Example 1: Plant Starch Soft Capsules

[0025] formula:

[0026] Hydroxypropyl starch 65g, carrageenan 30g, psyllium husk gum 5g, sodium alginate 3g, sodium hyaluronate 1.5g, meglumine 1g.

[0027] Preparation process:

[0028] (1) Raw material pretreatment: Hydroxypropyl starch was passed through a 90-mesh sieve and set aside. Carrageenan was appropriately pulverized and then passed through a 70-mesh sieve and set aside. The amount of psyllium husk gum specified in the formula was placed in 35°C warm water at 10 times its weight and left to stand for 1.2 hours for swelling treatment without stirring. Then, the amount of sodium hyaluronate and meglumine specified in the formula was added, and the hydration was started in stages: first, stirring at 55 rpm for 30 minutes, then stirring at 90 rpm for 1.2 hours, and finally stirring at 55 rpm for 1.5 hours to obtain a uniform psyllium husk gum mixture solution and set aside.

[0029] (2) Mixing and preparing the gelatin: Add purified water at a ratio of 7 times the weight of hydroxypropyl starch to the reactor and heat to 65°C. Slowly add the sieved hydroxypropyl starch to the reactor and stir at 120 rpm for 18 minutes to form a uniform starch suspension. Slowly add the prepared psyllium husk gum mixture to the starch suspension and continue stirring at 120 rpm for 18 minutes. Add the crushed and sieved carrageenan, increase the stirring speed to 180 rpm, and stir for 30 minutes while maintaining the temperature at 65°C. Finally, add sodium alginate and continue stirring at 180 rpm for 18 minutes to form a uniform colloidal solution.

[0030] (3) Vacuum degassing treatment: Transfer the above colloidal solution to a vacuum degassing device and degas for 20-25 minutes under a vacuum of -0.08 to -0.09 MPa.

[0031] (4) Soft capsule molding: A rotary soft capsule press is used for molding. The degassed colloidal solution is transported to the colloidal storage tank of the press. The press temperature is set to 45℃, the pressure to 1.0MPa, and the mold speed to 3 revolutions / minute.

[0032] (5) Drying: Place the formed soft capsules in a hot air circulating drying chamber for drying. The drying temperature is controlled at 25-30℃, the relative humidity is controlled at 30%-40%, and the moisture content is dried to 8%-12%.

[0033] Example 2: Plant Starch Soft Capsules

[0034] formula:

[0035] Hydroxypropyl starch 55g, carrageenan 20g, psyllium husk gum 2g, sodium alginate 1g, sodium hyaluronate 0.5g, meglumine 0.5g.

[0036] Preparation process:

[0037] (1) Raw material pretreatment: Hydroxypropyl starch was passed through an 80-mesh sieve and set aside. Carrageenan was appropriately pulverized and then passed through a 60-mesh sieve and set aside. The amount of psyllium husk gum specified in the formula was placed in 8 times its weight of warm water at 30°C and left to stand for 1 hour for swelling treatment without stirring. Then, the amount of sodium hyaluronate and meglumine specified in the formula was added, and the hydration was started in stages: first, stirring at 50 rpm for 20 minutes, then stirring at 80 rpm for 1 hour, and finally stirring at 50 rpm for 1 hour to obtain a uniform psyllium husk gum mixture solution, set aside.

[0038] (2) Mixing and preparing the gelatin: Add purified water at a ratio of 6 times the weight of hydroxypropyl starch to the reactor and heat to 60°C. Slowly add the sieved hydroxypropyl starch to the reactor and stir at 100 rpm for 15 minutes to form a uniform starch suspension. Slowly add the prepared psyllium husk gum mixture to the starch suspension and continue stirring at 100 rpm for 15 minutes. Add the crushed and sieved carrageenan, increase the stirring speed to 150 rpm, and stir for 25 minutes, maintaining the temperature at 60°C. Finally, add sodium alginate and continue stirring at 150 rpm for 15 minutes to form a uniform colloidal solution.

[0039] (3) Vacuum degassing treatment: Transfer the above colloidal solution to a vacuum degassing device and degas for 20-25 minutes under a vacuum of -0.08 to -0.09 MPa.

[0040] (4) Soft capsule molding: A rotary soft capsule press is used for molding. The degassed colloidal solution is transported to the colloidal storage tank of the press. The press temperature is set to 40℃, the pressure to 0.5MPa, and the mold speed to 2 revolutions / minute.

[0041] (5) Drying: Place the formed soft capsules in a hot air circulating drying chamber for drying. The drying temperature is controlled at 25-30℃, the relative humidity is controlled at 30%-40%, and the moisture content is dried to 8%-12%.

[0042] Example 3: Plant Starch Soft Capsules

[0043] formula:

[0044] Hydroxypropyl starch 75g, carrageenan 35g, psyllium husk gum 8g, sodium alginate 5g, sodium hyaluronate 2g, meglumine 2g.

[0045] Preparation process:

[0046] (1) Raw material pretreatment: Hydroxypropyl starch was passed through a 100-mesh sieve and set aside. Carrageenan was appropriately pulverized and then passed through an 80-mesh sieve and set aside. The amount of psyllium husk gum specified in the formula was placed in 12 times its weight of warm water at 40°C and left to stand for 1.5 hours for swelling treatment without stirring. Then, the amount of sodium hyaluronate and meglumine specified in the formula was added, and the hydration was started in stages: first, stirring at 60 rpm for 40 minutes, then stirring at 100 rpm for 1.5 hours, and finally stirring at 60 rpm for 2 hours to obtain a uniform psyllium husk gum mixture solution and set aside.

[0047] (2) Mixing and preparing the gelatin: Add purified water at 8 times the weight of hydroxypropyl starch to the reactor and heat to 70°C. Slowly add the sieved hydroxypropyl starch to the reactor and stir at 150 rpm for 20 minutes to form a uniform starch suspension. Slowly add the prepared psyllium husk gum mixture to the starch suspension and continue stirring at 150 rpm for 20 minutes. Add the crushed and sieved carrageenan, increase the stirring speed to 200 rpm, and stir for 35 minutes, maintaining the temperature at 70°C. Finally, add sodium alginate and continue stirring at 200 rpm for 20 minutes to form a uniform colloidal solution.

[0048] (3) Vacuum degassing treatment: Transfer the above colloidal solution to a vacuum degassing device and degas for 20-25 minutes under a vacuum of -0.08 to -0.09 MPa.

[0049] (4) Soft capsule molding: A rotary soft capsule press is used for molding. The degassed colloidal solution is transported to the colloidal storage tank of the press. The press temperature is set to 50℃, the pressure to 1.5MPa, and the mold speed to 4 revolutions / minute.

[0050] (5) Drying: Place the formed soft capsules in a hot air circulating drying chamber for drying. The drying temperature is controlled at 25-30℃, the relative humidity is controlled at 30%-40%, and the moisture content is dried to 8%-12%.

[0051] Single-factor experiment on plant starch soft capsules

[0052] This study aimed to verify the importance of the plant starch soft capsule formulation of this invention and clarify its key impact on the weather resistance (heat resistance at 75℃ and cold resistance at -28℃) of the plant starch soft capsules. Each experimental group contained 50 capsules. The preparation method was based on the method in Example 1. During the soft capsule forming stage, soybean oil was accurately injected as the content between two rubber sheets using a metering device. Under the action of a press, the rubber sheets encapsulated the content and were compressed into soft capsules.

[0053] Testing indicators:

[0054] Heat resistance: After being placed in a 75℃ constant temperature chamber for 24 hours, the soft capsule deformation rate (number of deformed capsules / total number of capsules) and oil leakage rate were recorded.

[0055] Cold resistance: After being placed in a -28℃ refrigerator for 24 hours and then restored to room temperature, the cracking rate and hardness change were recorded (soft capsule hardness tester, (hardness after treatment - initial hardness) / initial hardness × 100%).

[0056] 1. Necessity Verification Test for Plantain Seed Rubber

[0057] Variable settings:

[0058] (1) Missing group: The amount of plantain seed gum was 0g (other ingredients were added according to the amount in Example 1).

[0059] (2) Gradient group: the amount of plantain seed gum was set to 0.5g, 5g (Example 1), and 12g.

[0060] Table 1. Test data for the necessity verification of plantain seed rubber

[0061]

[0062] Table 1 illustrates the crucial impact of psyllium husk gum on weather resistance in plant starch soft capsule systems. When psyllium husk gum is absent, the heat and cold resistance of the soft capsules significantly decreases, failing to meet storage and transportation requirements under extreme temperature environments. With increasing psyllium husk gum dosage, the deformation, oil leakage, and cracking of the soft capsules gradually improve, reaching their optimal state at the dosage in Example 1, demonstrating its core role in constructing the colloidal network structure and enhancing system stability. Even when the dosage exceeds the optimal value, the performance is still better than the absence group and the low dosage group, indicating that psyllium husk gum must be used within a reasonable range to achieve the best synergistic effect.

[0063] 2. Necessity Verification Test for Sodium Hyaluronate

[0064] Variable settings:

[0065] (1) Deletion group: Sodium hyaluronate dosage was 0g.

[0066] (2) Gradient group: The amount of sodium hyaluronate was set to 0.1g, 1.5g (Example 1), and 5g.

[0067] Table 2. Necessity verification test data for sodium hyaluronate

[0068]

[0069] Table 2 illustrates that sodium hyaluronate is crucial for improving the weather resistance of plant starch soft capsules. Without sodium hyaluronate, the soft capsules are prone to deformation and oil leakage at high temperatures, and increased brittleness leading to cracking at low temperatures, resulting in significant performance degradation. As the amount of sodium hyaluronate approaches the optimal value of Example 1, the heat and cold resistance of the soft capsules continuously improves. At the optimal dosage, no deformation or cracking is achieved, fully demonstrating its role in enhancing colloidal flexibility through moisturizing properties. This indicates that the amount of sodium hyaluronate must be matched with other components to maintain the balance and stability of the system.

[0070] 3. Necessity verification test for meglumine

[0071] Variable settings:

[0072] (1) Deficiency group: The dosage of meglumine was 0g.

[0073] (2) Gradient group: The dosage of meglumine was set to 0.1g, 1g (Example 1), and 5g.

[0074] Table 3. Necessity verification test data for meglumine

[0075]

[0076] Table 3 illustrates the irreplaceable role of meglumine in optimizing weather resistance in plant starch soft capsules. The absence of meglumine significantly reduces both the heat and cold resistance of the soft capsules, highlighting its importance in regulating the compatibility of components. With increasing meglumine dosage, the probability of soft capsule deformation, oil leakage, and cracking gradually decreases, achieving optimal performance at the dosage in Example 1. This verifies its function of improving overall stability by enhancing inter-component interactions, indicating that meglumine must be controlled at a reasonable proportion to avoid negatively impacting the colloidal structure.

[0077] Experiment on the effect of staged hydration process on the weather resistance of plant starch soft capsules

[0078] Staged hydration is a key step in the preparation of psyllium husk gum mixed solution. By combining different stirring speeds and times, psyllium husk gum, sodium hyaluronate, and meglumine can be fully swollen and uniformly dispersed, thereby affecting the integrity of the colloidal network structure.

[0079] Based on the formulation of Example 1 (65g hydroxypropyl starch, 30g carrageenan, 5g psyllium husk gum, 3g sodium alginate, 1.5g sodium hyaluronate, and 1g meglumine), only the hydration process of the psyllium husk gum mixture was changed, while the other preparation steps (mixing and preparing the gum, degassing, molding, drying, etc.) remained the same.

[0080] Five experimental groups were set up, with 50 capsules in each group:

[0081] Example 1 Group (Baseline Group):

[0082] Staged hydration: Stir at 55 rpm for 30 minutes → Stir at 90 rpm for 1.2 hours → Stir at 55 rpm for 1.5 hours.

[0083] Example 2 group:

[0084] Staged hydration: Stir at 50 rpm for 20 minutes → Stir at 80 rpm for 1 hour → Stir at 50 rpm for 1 hour.

[0085] Example 3 group:

[0086] Staged hydration: Stir at 60 rpm for 40 minutes → Stir at 100 rpm for 1.5 hours → Stir at 60 rpm for 2 hours.

[0087] Unified speed comparison group:

[0088] Based on the formulation of Example 1, the mixture was continuously stirred at 70 rpm (the intermediate speed of the three reference groups) for 3.2 hours (the total time was the same as that of Example 1).

[0089] High-speed comparison group missing:

[0090] Based on the formulation of Example 1, only two-stage low-speed stirring was used: stirring at 50 rpm for 30 minutes → stirring at 60 rpm for 2.7 hours (the total time was the same as that of Example 1).

[0091] detection indicators

[0092] Heat resistance: After being placed in a 75℃ constant temperature chamber for 24 hours, the deformation rate (number of deformed items / total number of items) and oil leakage rate (number of oil leaks / total number of items) were recorded.

[0093] Cold resistance: After being placed in a -28℃ refrigerator for 24 hours and then restored to room temperature, the cracking rate (number of cracks / total number) and hardness change rate (percentage increase in hardness compared to the initial hardness) were recorded.

[0094] Experimental Data and Analysis

[0095] Table 4. Effects of staged hydration process on the weather resistance of plant starch soft capsules

[0096]

[0097] As shown in Table 4, the experimental results of Examples 1, 2, and 3, which employed a staged hydration process, exhibited excellent stability in both heat and cold resistance tests. This indicates that when the psyllium husk gum mixture is prepared using a staged hydration process of "low speed → high speed → low speed," sufficient swelling and uniform dispersion of each component can be achieved, thereby constructing a dense and stable colloidal network structure. This structure effectively resists the effects of extreme temperatures on the physical morphology of the soft capsules. Deformation and oil leakage risks at high temperatures, as well as cracking and abnormal hardness changes at low temperatures, are all comprehensively controlled, demonstrating the high compatibility between the staged hydration process and the formulation system.

[0098] Repairing Essence Capsules: Example 1: Plant starch soft capsules filled with a repairing essence containing ceramides and squalane. Their excellent weather resistance ensures the essence remains stable during transportation and storage, and its activity is not affected by temperature changes. These plant starch soft capsules can be used to encapsulate repairing essences, etc., serving as carriers of active ingredients in the cosmetics industry.

[0099] Sunscreen Capsules: Example 2 - Plant starch soft capsules encapsulate physical sunscreen ingredients zinc oxide and titanium dioxide, along with moisturizing ingredients. These capsules protect the sunscreen ingredients from oxidation. When used, the contents are squeezed out and evenly applied to the skin to form a uniform sunscreen film, effectively blocking UV rays while replenishing skin moisture. Suitable for daily commutes.

[0100] Firming and Anti-Wrinkle Essence Capsules: Example 3. Plant starch soft capsules are filled with a firming and anti-wrinkle essence containing retinol and peptides. Its stable structure ensures the activity of easily deactivated ingredients such as retinol. When using, apply the essence to the face and gently massage to promote collagen production, improve fine lines and wrinkles, and enhance skin firmness.

[0101] Moisturizing and Repairing Lip Mask Capsules: Example 1: Plant starch soft capsules filled with lip mask essence containing ingredients such as petrolatum and vitamin E. This seals against air, preventing oxidation of the ingredients. When using, apply the essence to the lips to deeply moisturize the lips, relieve dryness and peeling, and keep the lips soft and smooth.

[0102] Oil-controlling and acne-reducing gel capsules: Example 2: An oil-controlling and acne-reducing gel containing salicylic acid and tea tree oil, encapsulated in plant starch soft capsules. The capsules protect the stability of the gel ingredients. When applied to acne-prone areas, it effectively inhibits sebum secretion, kills Propionibacterium acnes, reduces acne inflammation, and promotes acne healing.

[0103] Brightening and Rejuvenating Essence Capsules: Example 3. Plant starch soft capsules containing a brightening essence with vitamin C derivatives and arbutin. Its excellent weather resistance ensures the stability of the essence ingredients. When applied to the face, it inhibits melanin production, fades dark spots, brightens skin tone, and leaves the skin with a radiant white glow.

Claims

1. A plant starch soft capsule, characterized in that, The plant starch soft capsules comprise the following components in parts by weight: 55-75 parts hydroxypropyl starch, 20-35 parts carrageenan, 2-8 parts psyllium husk gum, 1-5 parts sodium alginate, 0.5-2 parts sodium hyaluronate, and 0.5-2 parts meglumine. The preparation method of the plant starch soft capsules includes the following steps: (1) Raw material pretreatment: Hydroxypropyl starch and carrageenan are crushed and sieved separately for later use; plantain seed gum is allowed to stand in warm water to swell, sodium hyaluronate and meglumine are added, and it is hydrated in stages to obtain a plantain seed gum mixed solution for later use. The staged hydration is as follows: stirring at a speed of 50-60 rpm for 20-40 minutes, stirring at a speed of 80-100 rpm for 1-1.5 hours, and stirring at a speed of 50-60 rpm for 1-2 hours. (2) Mixing and preparing the gel: Heat purified water and add hydroxypropyl starch, psyllium husk gum mixture, carrageenan and sodium alginate respectively. Stir and mix evenly to form a uniform colloidal solution. (3) Vacuum degassing treatment of the colloidal solution from step (2); (4) Perform soft capsule forming on the colloidal solution after vacuum degassing; (5) Dry the soft capsules from step (4).

2. The plant starch soft capsule according to claim 1, characterized in that, The plant starch soft capsules comprise the following components in parts by weight: 65 parts hydroxypropyl starch, 30 parts carrageenan, 5 parts psyllium husk gum, 3 parts sodium alginate, 1.5 parts sodium hyaluronate, and 1 part meglumine.

3. The plant starch soft capsule according to claim 1, characterized in that, The preparation of the psyllium husk gum mixture is as follows: the psyllium husk gum is placed in 8-12 times its weight of warm water at 30-40℃ and left to stand for 1-1.5 hours for swelling treatment. Sodium hyaluronate and meglumine are added for staged hydration: first, the mixture is stirred at a speed of 50-60 rpm for 20-40 minutes, then at a speed of 80-100 rpm for 1-1.5 hours, and finally at a speed of 50-60 rpm for 1-2 hours to obtain a uniform psyllium husk gum mixture.

4. The plant starch soft capsule according to claim 1, characterized in that, The mixing and preparation steps are as follows: Take 6-8 times the weight of purified water of hydroxypropyl starch, heat to 60-70℃ and maintain, add hydroxypropyl starch, stir at 100-150 rpm for 15-20 minutes, add psyllium husk gum mixture, stir at 100-150 rpm for 15-20 minutes, add carrageenan, increase the stirring speed to 150-200 rpm, stir for 25-35 minutes, add sodium alginate, stir at 150-200 rpm for 15-20 minutes to form a uniform colloidal solution.

5. The plant starch soft capsule according to claim 1, characterized in that, The vacuum degassing process involves transferring the colloidal solution into a vacuum degassing device and degassing it for 20-25 minutes under a vacuum of -0.08 to -0.09 MPa.

6. The plant starch soft capsule according to claim 1, characterized in that, The soft capsule forming process is carried out using a rotary soft capsule press. The press temperature is 40-50℃, the pressure is 0.5-1.5MPa, and the mold rotation speed is 2-4 revolutions per minute.

7. The plant starch soft capsule according to claim 1, characterized in that, In the drying step, the drying temperature is controlled at 25-30℃, the relative humidity is controlled at 30%-40%, and the moisture content is dried to 8%-12%.

8. The application of the plant starch soft capsules according to claim 1 as a carrier of active ingredients in cosmetics in the preparation of cosmetics.

Images