Personal care formulations comprising 3-amino-3-methyl-2-butanol and uses thereof

Abstract

The present technology is generally directed to compositions comprising 3-amino-3-methyl-2-butanol. In particular, the present technology relates to a composition comprising 3-amino-3-methyl-2-butanol for use in personal care applications, such as a hair styling aerosol, a body lotion, mascara, a hair colorant, a sunscreen, a hand sanitizer, a cleaning agent, an eye cream, an exfoliating agent, a shampoo, a hair conditioner, a hair mask, a hair styling gel, a hair styling mousse, a dry shampoo, a non-aerosol type hair styling spray, a bath foam, a soap, a body scrub, a body butter, a lipstick, a foundation make-up, an eye shadow, a concealer, and a blusher. The present invention relates to eyeliner articles, eyebrow glues, lip gloss, lipsticks, make-up sprays and / or shaving creams.

Description

Cross-reference to related applications

[0001] This application claims the benefit and priority of U.S. Provisional Application No. 63 / 540,850, filed September 27, 2023, which is incorporated herein by reference in its entirety for any and all purposes. Technical Field

[0002] This technology generally relates to formulations containing 3-amino-3-methyl-2-butanol, which are used in personal care products, hair styling, creams, lotions, sunscreens, etc. background

[0003] Many commonly used products, including hair styling aerosols, non-aerosol (e.g., pump-type) sprays, hair styling gels, and hand sanitizers, are made from compositions using chemicals that are typically derived from non-renewable raw materials such as petroleum. For example, hair styling aerosols, hair styling gels, and hand sanitizers incorporate many petroleum-derived chemicals, including neutralizers designed to partially or completely neutralize acidic groups present in other chemicals in the composition.

[0004] The use of non-renewable petroleum-based raw materials leads to an over-reliance on fossil fuels. This dependence on non-renewable petroleum-based raw materials contributes to environmental degradation, such as air pollution, water pollution, and global warming. Furthermore, these fossil fuels are often supplied by politically unstable regions of the world, frequently raising humanitarian concerns.

[0005] Therefore, as explained in more detail above and below, there remains a need for compositions made from natural, renewable starting materials for commonly used products such as hair styling agents and disinfectants that offer comparable or better performance compared to existing products. Overview

[0006] This disclosure relates to compositions and formulations comprising 3-amino-3-methyl-2-butanol (also known as 3-amino-3-methylbut-2-ol; CAS No.: 13325-14-9) for use in personal care formulations. 3-Amino-3-methyl-2-butanol offers several advantages, including its improved sustainability characteristics, manifested in its ability to be manufactured as a renewable bio-based compound (i.e., not dependent on non-renewable petroleum-based raw materials) and its low toxicity (providing a safer alternative with reduced environmental and health impacts), while offering comparable or superior performance compared to petroleum-based alternatives and superior performance compared to current renewable alternatives (e.g., NH3). Therefore, the currently disclosed technology overcomes common adoption barriers associated with renewable personal care chemicals (e.g., poor performance and high cost), instead providing a high-performance, cost-effective solution with the potential for incorporation of bio-based carbon.

[0007] In one aspect, this technology provides compositions for personal care products comprising 3-amino-3-methyl-2-butanol. In some embodiments, the composition may be an aqueous based solution. For example, the composition may be an aqueous solution, a mixture, a dispersion, or an emulsion. In some embodiments, the composition may comprise a molecule containing an acidic group and an amount of 3-amino-3-methyl-2-butanol that effectively partially or completely neutralizes the acidic group, said molecule containing the acidic group may be a small molecule or polymer containing the acidic group. In some embodiments, the composition may comprise about 0.005 wt% to about 10 wt% of 3-amino-3-methyl-2-butanol. The composition may comprise a mixture of alcohol and water. Brief description of the attached diagram

[0008] Figure 1 The percentage of curl retention over time is provided for the use of Dow Hair Styling Resin in hair styling aerosols with various neutralizing agents (triisopropanolamine (also known as 1,1′,1′′-triazinetri(prop-2-ol)), 3-amino-3-methyl-2-butanol (AMB), triethanolamine, and 2-amino-2-methyl-1-propanol (AMP)). Figure 1 The results indicate that hair styling aerosols with AMB perform similarly to those with AMP in maintaining curl over time, and are significantly superior to those with triethanolamine (TEA) and triisopropanolamine (TIPA).

[0009] Figure 2 The results demonstrate high humidity curl retention over time when using Dow hair styling resin with multiple neutralizers AMP, AMB and triethanolamine in hair styling gel. Figure 2This indicates that hair styling gels with AMB perform similarly to hair styling gels with AMP, and are significantly superior to hair styling gels with TEA.

[0010] Figure 3A and 3B It is provided by using different amounts of thickener (i.e., 0.25 wt%). Figure 3A ) and 0.45 wt% Figure 3B A comparison of the effects of Carbopol 980 and different neutralizing agents (e.g., AMB and TEA) on the clarity of hand sanitizers. Figure 3A and 3B This indicates that hand sanitizers containing AMB provide similar clarity to hand sanitizers containing AMP, and significantly better clarity than hand sanitizers containing TEA.

[0011] Figure 4 This is a bar graph showing the effect of dispersants (triamino, AMP, AMB, TEA, NaOH) on the SPF of various sunscreen formulations. Formulations containing AMB provided the highest SPF rating among the tested formulations. Detailed Explanation

[0012] The following terms are used throughout the text and are defined as follows.

[0013] As used herein and in the appended claims, in the context of describing elements (particularly in the context of the appended claims), singular articles such as “a” and “an” and “the” and similar pronouns are to be interpreted as covering both the singular and plural, unless otherwise stated herein or obviously contradicted by the context. Unless otherwise stated herein, the description of the range of values ​​herein is intended only as a shorthand method for individually referring to each individual value falling within that range, and each individual value is incorporated into this specification as if it were individually described herein. All methods described herein may be performed in any suitable order, unless otherwise stated herein or obviously contradicted by the context. Unless otherwise stated, the use of any and all instances or exemplary language (e.g., “such as”) provided herein is intended only to better illustrate the embodiments and does not constitute a limitation on the scope of the claims. No language in this specification should be construed as indicating that any unclaimed element is essential.

[0014] As used herein, “about” will be understood by those skilled in the art and will vary to some extent depending on the context in which it is used. If those skilled in the art, considering the context in which the term is used, are unclear about its usage, “about” will mean a particular term plus or minus up to 10%—for example, “about 10 wt%” is understood to mean “9 wt% to 11 wt%”. It should be understood that when a term is preceded by “about”, the term should be interpreted as disclosing both the term “about” and any terms not modified by “about”—for example, “about 10 wt%” discloses both “9 wt% to 11 wt%” and “10 wt%”.

[0015] As used in this disclosure, the phrase “and / or” will be understood to mean any single member mentioned alone or any combination of two or more thereof—for example, “A, B and / or C” means “A or B or C; A and B; A and C; B and C; or a combination of A, B and C”.

[0016] The term "alkyl," whether alone or as part of another group (e.g., in dialkylamino), refers to a group comprising both straight-chain and branched aliphatic groups (i.e., saturated hydrocarbon chains) and, unless otherwise specified, having 1 to 10, optionally 1 to 8, or optionally 1 to 6 alkyl carbon atoms. Representative alkyl groups include, but are not limited to, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, sec-butyl, tert-butyl, pentyl, and hexyl. Unless otherwise specified, the alkyl group is optionally substituted with 1, 2, or 3, for example 1 or 2, or even only 1, substituent compatible with the compounds, monomers, and polymers described herein. In some embodiments, the alkyl group is unsubstituted.

[0017] The term "alkoxy" refers to a group in which oxygen is attached to a saturated straight-chain or branched alkyl group. Unless otherwise stated, an alkoxy group comprises 1 to 6 carbon atoms (e.g., methoxy, ethoxy, n-propoxy, isopropoxy, n-butoxy, isobutoxy, sec-butoxy, tert-butoxy, n-pentoxy, neopentoxy, isopentoxy, n-hexyloxy, or isohexyloxy), and in any embodiment, comprises 1 to 4 carbon atoms. In any embodiment, the alkoxy group may include methoxy, ethoxy, n-propoxy, isopropoxy, n-butoxy, isobutoxy, sec-butoxy, and tert-butoxy. In some embodiments, the alkoxy group is unsubstituted.

[0018] Groups having two or more attachment sites (i.e., divalent, trivalent, or polyvalent) in the compounds described herein are named using the suffix "ene". For example, a divalent alkyl group is alkylene, a divalent cycloalkyl group is cycloalkylene, and so on. Substituted groups having a single attachment site in the compounds of this technology are not referred to using the suffix "ene". Thus, for example, chloroethyl is not referred to herein as chloroethylene.

[0019] Generally, "substituted" refers to an alkyl group as defined above, in which one or more bonds with hydrogen atoms are replaced by bonds with non-hydrogen or non-carbon atoms. Substituted groups also include groups in which one or more bonds with carbon or hydrogen atoms are replaced by bonds with one or more heteroatoms (including double or triple bonds). In some embodiments, the substituted group is replaced by one, two, or three substituents. Examples of substituents include, but are not limited to, hydroxyl, amino, thiol, nitro, halogen, ester, amide, carbonyl, or carboxylic acid groups. Unless otherwise stated, the aforementioned substituents themselves are not further substituted.

[0020] Unless otherwise stated, all molecular weight (i.e. molar mass) data, number-average molecular weight data Mn, or weight-average molecular weight data Mw mentioned in this specification are molar masses, which can be determined by gel permeation chromatography (GPC).

[0021] As used herein, "fixative" refers to the film-forming component of a product. To form a film, a polymeric fixative (i.e., a polymer) can coalesce. Coalescing refers to a process in which the solvent (e.g., water and / or alcohol, such as ethanol) first evaporates, causing the polymeric fixative to aggregate together and then fuse into an irreversibly bonded network structure, making the product no longer soluble in the original carrier solvent. Polymer fixative resins are also referred to as "fixatives" and "polymer fixatives."

[0022] As used herein, “substantially free” means less than about 2 wt% of the specified component based on the total weight of the composition. In some embodiments, the composition may contain less than about 1 wt%, less than about 0.5 wt%, or less than about 0.1 wt% of the specified component. In some embodiments, the composition may be free of detectable amounts of the component.

[0023] 3-Amino-3-methyl-2-butanol ("AMB") composition In one aspect, the present technology provides compositions for use in personal care applications, such as in hair styling aerosols, body lotions, mascaras, hair colorants, sunscreens, hand sanitizers, cleansers, eye creams, exfoliants, shampoos, conditioners, hair masks, hair styling gels, hair styling mousses, dry shampoos, non-aerosol hair styling sprays, shower gels, soaps, body scrubs, body butters, lipsticks, foundations, eyeshadows, concealers, blushes, eyeliners, eyebrow gels, lip glosses, lipsticks, setting sprays, and / or shaving creams, wherein the compositions comprise about 30 wt% to about 99.99 wt% of 3-amino-3-methyl-2-butanol, about 0.01 wt% to about 70 wt% of water, and optionally amino alcohols other than 3-amino-3-methyl-2-butanol (“other amino alcohols”). In any embodiment, the composition may comprise 3-amino-3-methyl-2-butanol in amounts of about 30 wt%, about 35 wt%, about 40 wt%, about 45 wt%, about 50 wt%, about 55 wt%, about 60 wt%, about 65 wt%, about 70 wt%, about 75 wt%, about 80 wt%, about 85 wt%, about 90 wt%, about 95 wt%, about 96 wt%, about 97 wt%, about 98 wt%, about 99 wt%, about 99.5 wt%, about 99.9 wt%, about 99.95 wt%, about 99.99 wt%, or any range including any two of these values ​​and / or between any two of these values. For example, the composition may comprise 85 wt% to 95 wt% of 3-amino-3-methyl-2-butanol. In any embodiment, the composition may comprise at least about 90 wt% of 3-amino-3-methyl-2-butanol.

[0024] In any embodiment, the composition may contain 0.01 wt% to about 70 wt% water. These compositions may be solutions, such as homogeneous solutions, at room temperature. In any embodiment, the composition may comprise about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.5 wt%, about 1 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, about 10 wt%, about 11 wt%, about 12 wt%, about 13 wt%, about 14 wt%, about 15 wt%, about 16 wt%, about 17 wt%, about 18 wt%, about 19 wt%, about 20 wt%, about 21 wt%, about 22 wt%, about 23 wt%, about 24 wt%, about 25 wt%, about 30 wt%, about 35 wt%, about 40 wt%, about 45 wt%, about 50 wt%, about 55 wt%, about 60 wt%, about 65 wt%, about 70 wt%. The water content may be wt% or include any two of these values ​​and / or any range between any two of these values. Therefore, in any embodiment herein, the composition may contain 5 wt% to 15 wt% water or about 10 wt% water. The water may be deionized water, distilled water, or reverse osmosis (RO) water, or any combination thereof, including, for example, double-distilled water. In any embodiment herein, the purity and water content may be adjusted depending on the desired physical properties and end-use application.

[0025] In any embodiment of this document, water and / or other amino alcohols may be included in the composition comprising 3-amino-3-methyl-2-butanol, for example, to improve handling and / or alter performance characteristics. For example, adding water to a composition comprising 3-amino-3-methyl-2-butanol may increase the flash point, decrease the freezing point, and / or decrease the viscosity of the composition. Exemplary other amino alcohols that may be included in compositions in any embodiment of this document include, but are not limited to, 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof. The composition of any embodiment herein may comprise other amino alcohols (e.g., 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof) in amounts of at least about 0.01 wt%, at least about 0.02 wt%, at least about 0.03 wt%, at least about 0.04 wt%, at least about 0.05 wt%, at least about 0.06 wt%, at least about 0.07 wt%, at least about 0.08 wt%, at least about 0.09 wt%, at least about 0.1 wt%, at least about 0.25 wt%, at least about 0.5 wt%, at least about 0.75 wt%, at least about 1 wt%, at least about 1.5 wt%, at least about 2 wt%, at least about 2.5 wt%, at least about 3 wt%. wt%, at least about 3.5 wt%, at least about 4 wt%, at least about 4.5 wt%, or at least about 5 wt%, about 8 wt%, about 10 wt%, about 15 wt%, about 20 wt%, about 25 wt%, about 30 wt%, about 35 wt%, about 40 wt%, about 45 wt%, about 50 wt%, about 55 wt%, about 60 wt%, or any two of these values ​​and / or any range between any two of these values.The composition of any embodiment herein may comprise other amino alcohols (e.g., 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof) in amounts of no more than about 0.01 wt%, no more than about 0.02 wt%, no more than about 0.03 wt%, no more than about 0.04 wt%, no more than about 0.05 wt%, no more than about 0.06 wt%, no more than about 0.07 wt%, no more than about 0.08 wt%, no more than about 0.09 wt%, no more than about 0.1 wt%, no more than about 0.25 wt%, no more than about 0.5 wt%, no more than about 0.75 wt%, no more than about 1 wt%, no more than about 1.5 wt%, no more than about 2 wt%, not more than about 2.5 wt%, not more than about 3 wt%, not more than about 3.5 wt%, not more than about 4 wt%, not more than about 4.5 wt%, not more than about 5 wt%, or any two of these values ​​and / or any range between any two of these values.

[0026] In any embodiment herein, the composition may contain less than about 2 wt% of a secondary amine (e.g., 3-(ethylamino)-3-methylbut-2-ol, 2-(butamino)ethanol, diethanolamine, diisopropanolamine (also known as 1-(2-hydroxypropylamino)prop-2-ol), and / or dicyclohexylamine). Therefore, in any embodiment herein, the composition may contain less than about 2 wt%, less than about 1.5 wt%, less than about 1 wt%, less than about 0.5 wt%, or any two of these values ​​and / or any range between these values. For example, in any embodiment herein, the composition may contain less than about 0.5 wt% of a secondary amine.

[0027] In any embodiment herein, the composition may exhibit a bio-based content of 0% to 100% of 3-amino-3-methyl-2-butanol, as determined by radiocarbon analysis according to ASTM D6866-24. For example, such a range of bio-based content of 3-amino-3-methyl-2-butanol in compositions of the present technology can be provided by using pure petroleum-based 3-amino-3-methyl-2-butanol (i.e., having 0% bio-based content), using 3-amino-3-methyl-2-butanol produced partially from bio-based starting materials, using a combination of pure petroleum-based 3-amino-3-methyl-2-butanol and 3-amino-3-methyl-2-butanol produced partially or wholly from bio-based starting materials, or—for 100% bio-based content of 3-amino-3-methyl-2-butanol—using 3-amino-3-methyl-2-butanol produced entirely from bio-based starting materials. Therefore, in any embodiment herein, the composition may exhibit a bio-based content of 3-amino-3-methyl-2-butanol (determined by radiocarbon analysis according to ASTM D6866-24) of 0%, at least about 1%, at least about 5%, at least about 10%, at least about 15%, at least about 20%, at least about 25%, at least about 30%, at least about 35%, at least about 40%, at least about 45%, at least about 50%, at least about 55%, at least about 60%, at least about 70%, at least about 80%, at least about 90%, about 100%, or any two of these values ​​and / or any range between any two of these values. For example, the composition of any embodiment herein may exhibit a bio-based content of at least about 10% of 3-amino-3-methyl-2-butanol as determined by radiocarbon analysis according to ASTM D6866-24, or may exhibit a bio-based content of at least about 25% of 3-amino-3-methyl-2-butanol as determined by radiocarbon analysis according to ASTM D6866-24. Therefore, compositions of any aspect and / or embodiment herein may comprise renewable bio-based compounds (i.e., 3-amino-3-methyl-2-butanol) that exhibit low toxicity while providing performance comparable to or better than petroleum-based alternatives and superior to current renewable alternatives (e.g., NH3).

[0028] Personal care products containing 3-amino-3-methyl-2-butanol In one aspect, this technology provides compositions comprising 3-amino-3-methyl-2-butanol for use in personal care products. The compositions can be liquids, creams, scrubs, sticks, solutions, emulsions, dispersions, slurries, gels, foams, mousses, or pastes. Without being bound by any theory, incorporating 3-amino-3-methyl-2-butanol into personal care formulations can enhance the performance, rheology, and stability of a wide range of products. 3-amino-3-methyl-2-butanol can be used to adjust the pH, rheology, viscosity, emulsification, and / or product stability of the composition. In some embodiments, 3-amino-3-methyl-2-butanol can partially or completely replace pH adjusters (e.g., monoethanolamine (MEA), ammonia, and triethanolamine) commonly used in personal care products. In some embodiments, 3-amino-3-methyl-2-butanol can provide control over body odor and / or perspiration.

[0029] The compositions of this technology can be used as skin care products (e.g., cleansers, moisturizers, eye creams, exfoliants, sunscreens), hair care products (e.g., shampoos, conditioners, hair masks, styling gels, styling mousses, dry shampoos, styling aerosols, non-aerosol styling sprays, hair dyes), body care products (e.g., shower gels, soaps, body scrubs, body lotions, body butters, sunscreens) and / or cosmetics (e.g., color cosmetics, lipsticks, eyebrow gels, foundations, eyeshadows, concealers, blushes, eyeliners, mascaras, lip glosses, lipsticks, setting sprays) and / or personal hygiene products (e.g., shaving creams and hand sanitizers).

[0030] The compositions of this technology may contain a wide range of amounts of the 3-amino-3-methyl-2-butanol described herein. For example, the composition may contain 3-amino-3-methyl-2-butanol in amounts or subranges of about 0.005 wt% to about 10 wt% based on the total weight of the composition, such as about 0.01 wt% to about 10 wt%, about 0.05 wt% to about 8 wt%, about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 3 wt%, about 0.05 wt% to about 2 wt%, about 0.02 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.1 wt% to about 20 wt%, about 0.1 wt% to about 5 wt%, about 0.4 wt% to about 3 wt%, about 0.2 wt% to about 2 wt%, about 0.1 wt% to about 1 wt%, about 0.2 wt% to about 0.3 wt%, about 0.5 wt% to about 10 wt%, or any value or subrange thereof. In some embodiments, the composition may comprise about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, or about 10 wt%, or any two of these values ​​and / or any range between any two of these values. In some embodiments, the composition may comprise about 0.2 wt% to about 2 wt% of 3-amino-3-methyl-2-butanol based on the total weight of the composition.

[0031] In any aspect and / or embodiment thereof, the composition may further comprise an amino alcohol other than 3-amino-3-methyl-2-butanol (“other amino alcohols”), wherein exemplary other amino alcohols that may be included in the composition according to any embodiment thereof include, but are not limited to, 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof. The composition of any embodiment herein may comprise other amino alcohols (e.g., 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof) in amounts of at least about 0.01 wt%, at least about 0.02 wt%, at least about 0.03 wt%, at least about 0.04 wt%, at least about 0.05 wt%, at least about 0.06 wt%, at least about 0.07 wt%, at least about 0.08 wt%, at least about 0.09 wt%, at least about 0.1 wt%, at least about 0.25 wt%, at least about 0.5 wt%, at least about 0.75 wt%, at least about 1 wt%, at least about 1.5 wt%, at least about 2 wt%, at least about 2.5 wt%, at least about 3 wt%. wt%, at least about 3.5 wt%, at least about 4 wt%, at least about 4.5 wt%, at least about 5 wt%, about 8 wt%, about 10 wt%, about 15 wt%, about 20 wt%, about 25 wt%, about 30 wt%, about 35 wt%, about 40 wt%, about 45 wt%, about 50 wt%, about 55 wt%, about 60 wt%, or any two of these values ​​and / or any range between any two of these values.The composition of any embodiment herein may comprise other amino alcohols (e.g., 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof) in amounts of no more than about 0.01 wt%, no more than about 0.02 wt%, no more than about 0.03 wt%, no more than about 0.04 wt%, no more than about 0.05 wt%, no more than about 0.06 wt%, no more than about 0.07 wt%, no more than about 0.08 wt%, no more than about 0.09 wt%, no more than about 0.1 wt%, no more than about 0.25 wt%, no more than about 0.5 wt%, no more than about 0.75 wt%, no more than about 1 wt%, no more than about 1.5 wt%, no more than about 2 wt%, not more than about 2.5 wt%, not more than about 3 wt%, not more than about 3.5 wt%, not more than about 4 wt%, not more than about 4.5 wt%, not more than about 5 wt%, or any two of these values ​​and / or any range between any two of these values.

[0032] As previously discussed, the composition can exhibit a bio-based content of 0% to 100% of 3-amino-3-methyl-2-butanol, as determined by radiocarbon analysis according to ASTM D6866-24. Therefore, in any embodiment herein, the composition can exhibit a bio-based content of 3-amino-3-methyl-2-butanol (determined by radiocarbon analysis according to ASTM D6866-24) of 0%, at least about 1%, at least about 5%, at least about 10%, at least about 15%, at least about 20%, at least about 25%, at least about 30%, at least about 35%, at least about 40%, at least about 45%, at least about 50%, at least about 55%, at least about 60%, at least about 70%, at least about 80%, at least about 90%, about 100%, or any two of these values ​​and / or any range between any two of these values. For example, compositions of any embodiment herein may exhibit a bio-based content of at least about 10% of 3-amino-3-methyl-2-butanol as determined by radiocarbon analysis according to ASTM D6866-24, or may exhibit a bio-based content of at least about 25% of 3-amino-3-methyl-2-butanol as determined by radiocarbon analysis according to ASTM D6866-24. Therefore, 3-amino-3-methyl-2-butanol of any aspect and / or embodiment herein may be a renewable bio-based compound exhibiting low toxicity while providing performance comparable to or superior to petroleum-based alternatives and superior to current renewable alternatives (e.g., NH3).

[0033] The personal care compositions of this technology may contain solvents. Solvents may include water, alcohols (ethanol, isopropanol, or mixtures thereof), vegetable oils (e.g., coconut oil, olive oil, sunflower oil, avocado oil, almond oil, argan oil, jojoba oil, linseed oil, sesame oil, and / or hemp oil), animal oils (e.g., lanolin, beeswax, and / or tallow), mineral oils, glycerin, glycol ethers (e.g., butylene glycol, propylene glycol, hexane glycol, and / or ethylene glycol), organosilicon compounds (e.g., dimethicone, cyclopentasiloxane, cyclohexylsiloxane, trimethylsiloxysilicate, phenyl polytrimethylsiloxane, and / or polysiloxane-11), or any combination of two or more thereof. When preparing and / or applying the personal care compositions, the solvent may be used as a carrier. In some embodiments, the composition may comprise at least about 1 wt% of solvent, at least about 2 wt% of solvent, at least about 5 wt% of solvent, at least about 10 wt% of solvent, at least about 15 wt% of solvent, at least about 20 wt% of solvent, at least about 25 wt% of solvent, at least about 30 wt% of solvent, at least about 35 wt% of solvent, at least about 40 wt% of solvent, at least about 45 wt% of solvent, at least about 50 wt% of solvent, at least about 55 wt% of solvent, at least about 60 wt% of solvent, at least about 70 wt%, at least about 80 wt%, at least about 90 wt%, or include any two of these values ​​and / or any range of solvent between any two of these values. In some embodiments, the composition may comprise about 1 wt% to about 99 wt%, about 20 wt% to about 99 wt%, about 35 wt% to about 97 wt%, about 45 wt% to about 95 wt%, about 50 wt% to about 95 wt%, about 80 wt% to about 98 wt%, or a solvent comprising any two of these values ​​and / or any range between any two of these values. In some embodiments, the composition may comprise about 20 wt% to about 80 wt% of a solvent.

[0034] Personal care compositions of this technology may comprise a mixture of alcohol (e.g., ethanol, isopropanol, or mixtures thereof) and water. For example, the composition may comprise water to alcohol in the following weight ratios: 300:1 to about 1:300, such as about 300:1, about 150:1, about 75:1, about 37:1, about 18:1, about 9:1, about 4:1, about 3:1, about 2:1, about 1:1, about 1:2, about 1:3, about 1:4, about 1:9, about 1:18, about 1:37, about 1:75, about 1:150, about 1:300, or any two of these values ​​and / or any range between any two of these values.

[0035] The personal care compositions of this technology may comprise emulsions. The emulsion may be a water-in-oil or oil-in-water emulsion. In some embodiments, water may constitute the balance of the composition, ranging from about 20 wt% to about 80 wt% of the total composition. In addition to water, organic solvents may optionally be included as solvents. Examples include alcohols described herein, ester oils such as isopropyl myristate, hexadecyl myristate, 2-octyl dodecyl myristate, coconut oil, olive oil, sunflower oil, avocado oil, almond oil, argan oil, jojoba oil, linseed oil, sesame oil, hemp oil, and mineral oil. Such ester oils can help emulsify such emulsion compositions. The composition may contain additional emulsifiers (e.g., stearic acid). 3-Amino-3-methyl-2-butanol may also help emulsify such emulsion compositions. When the composition comprises an emulsion and a pigment, the pigment may be dispersed in an oil phase or an aqueous phase.

[0036] Acidic neutralizing additives for partially or completely neutralizing acidic groups of acids and / or polymers include 2-amino-2-methyl-1-propanol (AMP), 2-amino-2-methyl-1,3-propanediol (AMPD), ammonium hydroxide, morpholine, cyclohexylamine, dimethylstearylamine (DMS), monoethanolamine (MEA), diethanolamine (DEA), triethanolamine (TEA), monoisopropanolamine (MIPA), and triisopropanolamine (TIPA). 3-Amino-3-methyl-2-butanol can be used to partially or completely replace one or more of these neutralizing agents. The composition may have a pH of about 5 to about 9, about 5.5 to about 8.5, about 6 to about 8, about 6.5 to about 7.5, or about 7.

[0037] In any embodiment herein, the composition may comprise a molecule containing an acidic group (i.e., one or more acidic groups) and a neutralizing agent (i.e., 3-amino-3-methyl-2-butanol) and a solvent that effectively partially or completely neutralizes the amount of the acidic group. The molecule containing the acidic group may further be a polymer as described herein.

[0038] In some embodiments, the composition may comprise about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, about 10 wt%, 15 wt%, 20 wt%, 25 wt%, 30 wt%, 35 wt%, or 40 wt%, or any two of these values ​​and / or any range between any two of these values, of molecules containing acidic groups. The composition may comprise from about 0.001 wt% to about 40 wt%, for example, from about 0.01 wt% to about 40 wt%, from about 0.05 wt% to about 15 wt%, from about 0.1 wt% to about 5 wt%, from about 10 wt% to about 30 wt%, or include any two of these values ​​and / or any range between any two of these values ​​of molecules containing acidic groups. In some embodiments, the composition may comprise from about 0.1 wt% to about 5 wt% of molecules containing acidic groups.

[0039] The acidic groups of molecules containing acidic groups may include carboxylic acids, sulfonic acids, phosphonic acids, and / or phosphate groups. The composition may comprise one or more molecules having acidic groups, each molecule independently having an acidic group selected from the group consisting of carboxylic acids, sulfonic acids, phosphonic acids, phosphate groups, or combinations of two or more thereof. In some embodiments, the molecules containing acidic groups include carboxylic acids. Carboxylic acids may include α-hydroxycarboxylic acids (“AHA”; for example, glycolic acid, lactic acid, mandelic acid, and citric acid) and / or alkyl ether carboxylic acids. For example, carboxylic acids may include isostearic acid, lauric acid, palmitic acid, oleic acid, stearic acid, lactic acid, myristic acid, acetic acid, propionic acid, succinic acid, glutaric acid, adipic acid, hexanoic acid, heptanoic acid, octanoic acid, sebacic acid, citric acid, and any combination of two or more thereof. In some embodiments, the molecules containing acidic groups include sulfonic acids. Sulfonic acids may include those having the formulas ROSO3M and RO(C2H4O), respectively. x SO3M is an alkyl sulfate and / or alkyl ether sulfate, wherein R is an alkyl or alkenyl group with 8 to 18 carbon atoms, x is an integer from about 1 to about 10, and M is a cation such as ammonium, an alkanolamine such as triethanolamine, a monovalent metal such as sodium and potassium, and a polyvalent metal cation such as magnesium and calcium. For example, R may have 12 to 14 carbon atoms in a straight chain rather than a branched chain. For example, sulfonic acid may include sodium lauryl sulfate and sodium lauryl ether sulfate and combinations thereof. For example, the phosphate group may be a hexadecyl phosphate.

[0040] Any composition disclosed herein may further comprise esters, such as isopropyl isostearate, hexyl laurate, isohexyl laurate, isohexyl palmitate, isopropyl palmitate, decyl oleate, isodecyl oleate, hexadecyl stearate, decyl stearate, isopropyl isostearate, dihexyl decyl adipate, lauryl lactate, myristyl lactate, hexadecyl lactate, oleyl stearate, oleyl oleate, oleyl myristate, lauryl acetate, hexadecyl propionate, oleyl adipate, C7 to C22 esters of succinate, diisopropyl adipate, diisohexyl adipate, diisopropyl sebacate, isohexyl stearyl stearate, tristearate citrate, and any combination of two or more thereof.

[0041] In some embodiments, 3-amino-3-methyl-2-butanol neutralizes at least about 20% (e.g., at least about 30%, at least about 40%, or at least about 50%) of the molecule containing the acidic group. In some embodiments, 3-amino-3-methyl-2-butanol neutralizes from about 20% to about 100% (e.g., from about 30% to about 90% or from about 40% to about 80%) of the molecule containing the acidic group. In some embodiments, the molar ratio of 3-amino-3-methyl-2-butanol to the molecule containing the acidic group can be from about 1:5 to about 5:1 (e.g., from about 1:4 to about 2:1, from about 1:3 to about 2:1, or from about 1:2 to about 1:1).

[0042] In some embodiments, the molecule containing the acidic group may be a polymer (e.g., a polymer containing one or more acidic groups). The composition may comprise a polymer, a neutralizing agent (e.g., 3-amino-3-methyl-2-butanol) that effectively partially or completely neutralizes the amount of acidic groups, and a solvent.

[0043] In some embodiments, the composition may comprise about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, about 10 wt%, 15 wt%, 20 wt%, 25 wt%, 30 wt%, 35 wt%, or 40 wt%, or any two of these values ​​and / or any range between any two of these values, of a polymer containing acidic groups. The composition may comprise from about 0.001 wt% to about 40 wt%, for example, from about 0.01 wt% to about 40 wt%, from about 0.05 wt% to about 15 wt%, from about 0.1 wt% to about 5 wt%, from about 0.5 wt% to about 4 wt%, from about 0.1 wt% to about 1 wt%, from about 10 wt% to about 30 wt%, from about 2 wt% to about 15 wt%, or include any two of these values ​​and / or any range between any two of these values ​​of a polymer containing acidic groups. In some embodiments, the composition may comprise from about 0.1 wt% to about 5 wt% of a polymer containing acidic groups.

[0044] The acidic groups of polymers containing acidic groups may include carboxyl, sulfonyl, phosphonyl, phosphoryl, or any combination of two or more thereof. In some embodiments, the composition may comprise more than one polymer having an acidic group, each polymer having an acidic group independently selected from carboxyl, sulfonyl, phosphonyl, phosphoryl, or any combination of two or more thereof. In some embodiments, the acidic functional group is a carboxyl group. In some embodiments, the polymer may have an acid value of about 0.1 to about 10 mEq / g. In some embodiments, the polymer may have an acid value of about 0.5 to about 5 mEq / g or about 1 to about 4 mg mEq / g.

[0045] The polymer containing acidic groups may be selected from the group consisting of polyacrylate copolymers, vinyl acetate copolymers, or combinations thereof. In some embodiments, the polymer containing acidic groups may be ethyl acrylate, methyl methacrylate, and methacrylic acid copolymers; ethyl acrylate, tert-butyl acrylate, and methacrylic acid copolymers; octylacrylamide, acrylate, and butylaminoethyl methacrylate copolymers; methacrylic acid, n-butyl acrylate, and methyl methacrylate copolymers; methacrylic acid, n-butyl acrylate, and ethyl methacrylate copolymers; butyl acrylate, methyl methacrylate, hydroxyethyl methacrylate, and methacrylic acid copolymers; vinyl acetate, crotonate, and neodecanoate copolymers; butyl ester of vinyl methyl ether and maleic anhydride copolymers; ethyl ester of vinyl methyl ether and maleic anhydride copolymers; vinyl acetate and vinylpyrrolidone copolymers; acrylate / steareth-20 methacrylate crosspolymers; hyaluronic acid; carbomer; or copolymers or mixtures of any two or more thereof.

[0046] The compositions of this technology may comprise one or more polymers containing acidic groups having a wide range of molecular weights. For example, the compositions may comprise polymers containing acidic groups having the following average molecular weights: at least about 10 kDa, at least about 25 kDa, at least about 50 kDa, at least about 100 kDa, at least about 150 kDa, at least about 200 kDa, at least about 250 kDa, at least about 300 kDa, at least about 400 kDa, at least about 500 kDa, at least about 600 kDa, at least about 700 kDa, at least about 800 kDa, at least about 900 kDa, or at least about 1000 kDa, or a range between and including any two of the foregoing values. For example, the composition may comprise a polymer containing acidic groups having the following average molecular weights: about 10 kDa to about 1000 kDa, about 25 kDa to about 500 kDa, about 300 kDa to about 400 kDa, 600 kDa to about 700 kDa, or about 50 kDa to about 300 kDa. The polymer containing acidic groups may be crosslinked.

[0047] In some embodiments, 3-amino-3-methyl-2-butanol neutralizes at least about 20% (e.g., at least about 30%, at least about 40%, or at least about 50%) of the acidic functional groups on the polymer. In some embodiments, 3-amino-3-methyl-2-butanol neutralizes about 20% to about 100% (e.g., about 30% to about 90% or about 40% to about 80%) of the acidic functional groups on the polymer. In some embodiments, the molar ratio of 3-amino-3-methyl-2-butanol to the acidic functional groups on the polymer can be about 1:5 to about 5:1 (e.g., about 1:4 to about 2:1, about 1:3 to about 2:1, or about 1:2 to about 1:1).

[0048] In any embodiment, the composition may further comprise one or more additives selected from preservatives, thickeners, water-miscible cosolvents, water-immiscible cosolvents, antimicrobial agents, nonionic polymers, dyes, fragrances, and corrosion inhibitors.

[0049] In some embodiments, the composition may comprise anionic and / or amphoteric surfactants. The anionic and / or amphoteric surfactants may be selected from the group consisting of fatty acids, alkyl sulfates, alkyl(oxoalkyl)(n) sulfates (where n is an average degree of alkoxylation of 1 to 3), alkyl sulfonates, alkenyl sulfonates, alkylamides, alkyl betaines, and combinations of two or more thereof. For example, the anionic and / or amphoteric surfactant may be sodium lauryl sulfate, ammonium lauryl sulfate, sodium laureth(n) sulfate, or ammonium lauryl ether(n) sulfate (where n is an average degree of ethoxylation of 1 to 3), alkoxyalkyl lauryl sulfate, sodium laureth sulfate, cocamidopropyl betaine, and combinations of two or more thereof. In some embodiments, the composition may comprise about 1% to about 50% of the anionic and / or amphoteric surfactant. In some embodiments, the composition may comprise about 5% to about 40% of the anionic and / or amphoteric surfactant.

[0050] In some embodiments, the composition may comprise an alcohol. In some embodiments, the alcohol may be ethanol, n-propanol, isopropanol, or a combination of two or more thereof. For example, in some embodiments, the composition may comprise at least about 20 wt% of an alcohol, at least about 25 wt% of an alcohol, at least about 30 wt% of an alcohol, at least about 35 wt% of an alcohol, at least about 40 wt% of an alcohol, at least about 45 wt% of an alcohol, at least about 50 wt% of an alcohol, at least about 55 wt% of an alcohol, at least about 60 wt% of an alcohol, at least about 65 wt% of an alcohol, at least about 70 wt% of an alcohol, at least about 75 wt% of an alcohol, at least about 80 wt% of an alcohol, at least about 85 wt% of an alcohol, at least about 90 wt% of an alcohol, or an alcohol ranging from and including any two of the foregoing values. For example, in some embodiments, the composition may contain about 40% to about 95% of alcohol, about 50% to about 80% of alcohol, or about 60% to about 70% of alcohol.

[0051] Hair styling aerosols and similar products In one aspect, this technology provides compositions for hair styling aerosols and similar products, said compositions comprising an acrylate resin, a neutralizing agent (i.e., 3-amino-3-methyl-2-butanol), a propellant, and / or a solvent. Unbound by any theory, 3-amino-3-methyl-2-butanol, in addition to acting as a neutralizing agent, can also provide in-can corrosion protection.

[0052] In some embodiments, the hair styling aerosol composition may comprise an acrylic resin. For example, the acrylic resin may comprise an acrylate / hydroxy acrylate copolymer. The acrylic resin may comprise AMPHOMER® (Nouryon), ACUTYNE™ 180 (Dow), ACUTYNE 1000 (Dow), AMERHOLD, LUVIMER 100P, LUVIMER 36D, LUVIMER 30E, ACULYN 88, ACULYN 44, ACULYN 33A, or any combination of two or more thereof. In some embodiments, the composition may comprise an acetate resin or a combination of acetate and acrylate resins. For example, RESYN 28-2930, GANTREZ ES-225, and LUVISKOL VA may also be used. The amount of such resin can be in the range of about 0.001 wt% to about 15 wt%, for example, any one of about 0.001 wt%, 0.01 wt%, 0.1 wt%, 1 wt%, 2 wt%, 3 wt%, 5 wt%, 6 wt%, 7 wt%, 8 wt%, 9 wt%, 10 wt%, 11 wt%, 12 wt%, 13 wt%, 14 wt%, or 15 wt%, or a range between and including any two of the aforementioned values, for example, about 0.2 wt% to about 15 wt%, 0.02 wt% to about 0.3 wt%, 2 wt% to about 15 wt%, about 2 wt% to about 4 wt%, about 4 wt% to about 7 wt%, or about 6 wt% to about 10 wt%.

[0053] In some embodiments, the hair styling aerosol composition may contain a propellant, such as propane, butane, isobutane, dimethyl ether, 1,1-difluoroethane, methyl acetate, or a combination of two or more thereof. A VOC propellant may constitute about 30-35 wt% of the composition. A low-VOC propellant, such as 152A, may constitute 40-50% of the composition.

[0054] Hair styling aerosol compositions may contain a wide range of amounts of the neutralizing agent 3-amino-3-methyl-2-butanol described herein. For example, the composition may contain 3-amino-3-methyl-2-butanol in amounts or subranges of about 0.005 wt% to about 10 wt% based on the total weight of the composition, such as about 0.01 wt% to about 10 wt%, about 0.05 wt% to about 8 wt%, about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 3 wt%, about 0.05 wt% to about 2 wt%, about 0.02 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.1 wt% to about 20 wt%, about 0.1 wt% to about 5 wt%, about 0.4 wt% to about 3 wt%, about 0.2 wt% to about 2 wt%, about 0.1 wt% to about 1 wt%, about 0.2 wt% to about 0.3 wt%, about 0.5 wt% to about 10 wt%, or any value or subrange thereof. In some embodiments, the composition may comprise about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, or about 10 wt%, or any two of these values ​​and / or any range between any two of these values. In some embodiments, the composition may comprise about 0.4 wt% to about 3 wt% of 3-amino-3-methyl-2-butanol based on the total weight of the composition.

[0055] Hair styling aerosol compositions may contain water. In some embodiments, the composition may contain at least about 5 wt% water, at least about 10 wt% water, at least about 15 wt% water, at least about 20 wt% water, at least about 25 wt% water, at least about 30 wt% water, at least about 40 wt% water, at least about 50 wt% water, at least about 60 wt% water, at least about 70 wt% water, at least about 80 wt% water, at least about 85 wt% water, at least about 90 wt% water, or water in the range of any two of the foregoing values. In some embodiments, the composition may contain less than 1 wt%, less than 0.1 wt%, less than 0.01 wt%, or less than 0.001 wt% water. In some embodiments, the composition may contain about 0.001 wt% to about 0.1 wt%, about 0.01 wt% to about 1 wt%, or about 5 wt% to about 30 wt% water. In some embodiments, the composition may contain about 25 wt% to about 35 wt% water.

[0056] Hair styling aerosol compositions may also contain alcohols (e.g., ethanol). In some embodiments, the composition may contain at least about 20 wt%, at least about 25 wt%, at least about 30 wt%, at least about 35 wt%, at least about 40 wt%, at least about 45 wt%, at least about 50 wt%, at least about 55 wt%, at least about 60 wt%, at least about 65 wt%, at least about 70 wt%, at least about 75 wt%, at least about 80 wt%, at least about 85 wt%, at least about 90 wt%, or a range between and including any two of the foregoing values. For example, in some embodiments, the composition contains about 10 wt% to about 90 wt%, or about 40 wt% to about 60 wt% of ethanol. In some embodiments, the composition contains about 50 wt% of ethanol.

[0057] Hair styling gels and similar products In one aspect, this technology provides compositions for hair styling gels and similar products, said compositions comprising film-forming and fixing agents (e.g., ACUTYNE™ 1000), neutralizing agents (i.e., 3-amino-3-methyl-2-butanol), suspending and stabilizing agents (e.g., ACULYN™ 88), preservatives (e.g., Euxyl® PE 9010), and / or water. The compositions of this technology may contain a polymer containing acidic groups (e.g., ACUTYNE™ 1000) used as a film-forming and / or fixing agent. The film-forming and / or fixing agent may comprise an acrylate / hydroxy acrylate copolymer.

[0058] For example, a hair styling gel composition may comprise, based on about 0.01 wt% to about 10 wt% of the total weight of the composition, about 0.05 wt% to about 5 wt%, about 0.5 wt% to about 4 wt%, about 1 wt% to about 3 wt%, or about 1.5 wt% to about 2.5 wt% of film-forming agents and fixing agents. In some embodiments, the composition may comprise about 0.5 wt%, about 1.0 wt%, about 1.5 wt%, about 1.6 wt%, about 1.7 wt%, about 1.8 wt%, about 1.9 wt%, about 2.0 wt%, about 2.1 wt%, about 2.2 wt%, about 2.3 wt%, about 2.4 wt%, about 2.5 wt%, about 3.0 wt%, about 3.5 wt%, about 4.0 wt%, or about 5.0 wt%, or a range between and including any two of the foregoing values, of film-forming agents and fixing agents.

[0059] Hair styling gel compositions may contain suspending agents and stabilizers (e.g., ACULYN™ 88). For example, the composition may contain suspending agents and stabilizers in amounts of about 0.005 wt% to about 10 wt% based on the total weight of the composition, including about 0.05 wt% to about 5 wt%, about 1 wt% to about 4 wt%, about 2 wt% to about 4 wt%, or about 2.5 wt% to about 3.5 wt%. In some embodiments, the composition may contain about 0.5 wt%, about 1.0 wt%, about 1.5 wt%, about 2.0 wt%, about 2.5 wt%, about 2.6 wt%, about 2.7 wt%, about 2.8 wt%, about 2.9 wt%, about 3.0 wt%, about 3.1 wt%, about 3.2 wt%, about 3.3 wt%, about 3.4 wt%, about 3.5 wt%, about 4.0 wt%, about 4.5 wt%, or about 5.0 wt%, or a range between and including any two of the foregoing values.

[0060] Hair styling gel compositions may contain a wide range of amounts of the neutralizing agent 3-amino-3-methyl-2-butanol described herein. For example, the composition may contain 3-amino-3-methyl-2-butanol in amounts or subranges of about 0.005 wt% to about 10 wt% based on the total weight of the composition, such as about 0.01 wt% to about 10 wt%, about 0.05 wt% to about 8 wt%, about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 3 wt%, about 0.05 wt% to about 2 wt%, about 0.02 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.1 wt% to about 20 wt%, about 0.1 wt% to about 5 wt%, about 0.4 wt% to about 3 wt%, about 0.2 wt% to about 2 wt%, about 0.1 wt% to about 1 wt%, about 0.2 wt% to about 0.3 wt%, about 0.5 wt% to about 10 wt%, or any value or subrange thereof. In some embodiments, the composition may comprise about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, or about 10 wt%, or any two of these values ​​and / or any range between any two of these values. In some embodiments, the composition may comprise about 0.1 wt% to about 0.5 wt% of 3-amino-3-methyl-2-butanol based on the total weight of the composition.

[0061] The hair styling gel composition may contain water. In some embodiments, the composition may contain at least about 20 wt% water, at least about 25 wt% water, at least about 30 wt% water, at least about 35 wt% water, at least about 40 wt% water, at least about 45 wt% water, at least about 50 wt% water, at least about 55 wt% water, at least about 60 wt% water, at least about 65 wt% water, at least about 70 wt% water, at least about 75 wt% water, at least about 80 wt% water, at least about 85 wt% water, at least about 90 wt% water, or a range of water between and including any two of the foregoing values. In some embodiments, the composition may contain about 20 wt% to about 99 wt%, about 35 wt% to about 97 wt%, about 45 wt% to about 95 wt%, about 50 wt% to about 95 wt% water, or a range of water between and including any two of the foregoing values. In some embodiments, the composition may contain about 93 wt% to about 98 wt% water.

[0062] The compositions of this technology can contain a wide range of preservatives (e.g., Euxyl® PE 9010). For example, the composition can contain preservatives in amounts from about 0.01 wt% to about 10 wt% of the total weight of the composition, including about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.25 wt% to about 0.75 wt%, about 0.35 wt% to about 0.65 wt%, or about 0.4 wt% to about 0.6 wt%. In some embodiments, the composition may contain about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.6 wt%, about 0.7 wt%, about 0.8 wt%, about 0.9 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, or about 5 wt%, or a range between and including any two of the foregoing values.

[0063] Hand sanitizers and similar products In one aspect, the present technology provides compositions for hand sanitizers and similar products, the compositions comprising a thickener (e.g., Carbopol® 980, a polymer containing an acidic group), a neutralizer (i.e., 3-amino-3-methyl-2-butanol), a disinfectant (e.g., ethanol), and / or water.

[0064] The hand sanitizer of this technology may contain a wide range of amounts of the neutralizing agent 3-amino-3-methyl-2-butanol described herein. For example, the composition may contain 3-amino-3-methyl-2-butanol in amounts or subranges of about 0.005 wt% to about 10 wt% based on the total weight of the composition, such as about 0.01 wt% to about 10 wt%, about 0.05 wt% to about 8 wt%, about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 3 wt%, about 0.05 wt% to about 2 wt%, about 0.02 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.1 wt% to about 20 wt%, about 0.1 wt% to about 5 wt%, about 0.4 wt% to about 3 wt%, about 0.2 wt% to about 2 wt%, about 0.1 wt% to about 1 wt%, about 0.2 wt% to about 0.3 wt%, about 0.5 wt% to about 10 wt%, or any value or subrange thereof. In some embodiments, the composition may comprise about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, or about 10 wt%, or any two of these values ​​and / or any range between any two of these values. In some embodiments, the composition may comprise about 0.01 wt% to about 0.1 wt% of 3-amino-3-methyl-2-butanol based on the total weight of the composition.

[0065] The hand sanitizer composition of this technology may contain a thickener, such as Carbopol® 980 (crosslinked polyacrylic acid) or an acrylate / stearyl ether-20 methacrylate crosslinked polymer. For example, the composition may contain a thickener comprising about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 2 wt%, about 0.05 wt% to about 0.5 wt%, about 0.05 wt% to about 0.3 wt%, about 0.1 wt% to about 0.3 wt%, or about 0.2 wt% to about 0.3 wt% based on about 0.05 wt% to about 10 wt% of the total weight of the composition. In some embodiments, the composition may comprise about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.25 wt%, about 0.3 wt%, about 0.35 wt%, about 0.4 wt%, about 0.45 wt%, about 0.5 wt%, about 0.75 wt%, or about 1 wt%, or a range between and including any two of the foregoing values.

[0066] The hand sanitizer composition of this technology may contain water. In some embodiments, the composition may contain at least about 10 wt% water, at least about 15 wt% water, at least about 20 wt% water, at least about 25 wt% water, at least about 30 wt% water, at least about 35 wt% water, or at least about 40 wt% water, or a range between and including any two of the foregoing values. In some embodiments, the composition may contain about 20 wt% to about 40 wt%, about 25 wt% to about 35 wt%, about 27 wt% to about 33 wt%, about 28 wt% to about 32 wt% water, or a range between and including any two of the foregoing values.

[0067] The hand sanitizer composition of this technology may also contain alcohols, such as ethanol, isopropanol, or mixtures thereof. In some embodiments, the composition may contain at least about 20 wt% of an alcohol, at least about 25 wt% of an alcohol, at least about 30 wt% of an alcohol, at least about 35 wt% of an alcohol, at least about 40 wt% of an alcohol, at least about 45 wt% of an alcohol, at least about 50 wt% of an alcohol, at least about 55 wt% of an alcohol, at least about 60 wt% of an alcohol, at least about 65 wt% of an alcohol, at least about 70 wt% of an alcohol, at least about 75 wt% of an alcohol, at least about 80 wt% of an alcohol, at least about 85 wt% of an alcohol, at least about 90 wt% of an alcohol, or an alcohol ranging from and including any two of the foregoing values.

[0068] Coloring products and sunscreens Personal care compositions of this technology may contain pigments (e.g., used as sunscreens and / or coloring cosmetics). Examples of coloring cosmetics include lipsticks, foundations, concealers, blushes, eyeshadows, eyeliners, lip glosses, lipsticks, eyebrow gels, tinted sunscreens, and similar products. Pigments may be in powder form, such that the composition is an emulsion or dispersion. In some embodiments, the pigment may be a metal, metal oxide, ceramic, or carbon-containing material. Illustrative pigments include titanium dioxide, zinc oxide, black iron oxide, red iron oxide, aluminum oxide, aluminum metal, mica, ultramarine, magenta, carbon black, and any combination of two or more thereof. The composition may contain about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, about 10 wt%, 15 wt%, 20 wt%, 25 wt%, 30 wt%, 35 wt%, or 40 wt%, or any two of these values ​​and / or any range between any two of these values ​​of pigment. The composition may contain about 0.001 wt% to about 40 wt%, such as about 0.01 wt% to about 40 wt%, about 0.05 wt% to about 15 wt%, about 0.1 wt% to about 5 wt%, about 0.5 wt% to about 4 wt%, about 0.1 wt% to about 1 wt%, about 10 wt% to about 30 wt%, about 2 wt% to about 20 wt%, or include any two of these values ​​and / or any range between any two of these values ​​of pigment.

[0069] In one aspect, this technology provides compositions for use in coloring cosmetics and similar products. Coloring cosmetics may comprise pigments, neutralizing agents (i.e., 3-amino-3-methyl-2-butanol), and solvents.

[0070] In one aspect, this technology provides compositions for sunscreens and similar products. The sunscreen composition may be a mineral sunscreen composition comprising pigments, surfactants (e.g., fatty acids such as stearic acid), neutralizing agents (i.e., 3-amino-3-methyl-2-butanol), and solvents. The sunscreen composition may optionally or additionally comprise chemical sunscreens (e.g., phenylbenzimidazole sulfonic acid and aminobenzoic acid), neutralizing agents (i.e., 3-amino-3-methyl-2-butanol), and solvents.

[0071] In some embodiments of the sunscreen composition, the pigment comprises a metal oxide used as a mineral sunscreen. For example, the pigment may include titanium dioxide, zinc oxide, or a combination thereof. The amount of such pigment may range from about 2 wt% to about 75 wt%, for example, any one of about 2 wt%, 4 wt%, 6 wt%, 8 wt%, 10 wt%, 12 wt%, 14 wt%, 16 wt%, 18 wt%, 20 wt%, 25 wt%, 30 wt%, 35 wt%, 40 wt%, 45 wt%, 50 wt%, 55 wt%, 60 wt%, 65 wt%, 70 wt%, or 75 wt%, or a range between and including any two of the foregoing values, for example, about 5 wt% to about 30 wt%, about 10 wt% to about 20 wt%, or about 14 wt%.

[0072] In some embodiments of the sunscreen composition, the chemical sunscreen agent includes phenylbenzimidazole sulfonic acid and / or aminobenzoic acid (e.g., para-aminobenzoic acid (PABA), glyceryl PABA, pardimethicone O (octyldimethyl PABA), roxalate, and any combination of two or more thereof). The amount of such chemical sunscreen agent can range from about 2 wt% to about 75 wt%, for example, any one of about 2 wt%, 4 wt%, 6 wt%, 8 wt%, 10 wt%, 12 wt%, 14 wt%, 16 wt%, 18 wt%, 20 wt%, 25 wt%, 30 wt%, 35 wt%, 40 wt%, 45 wt%, 50 wt%, 55 wt%, 60 wt%, 65 wt%, 70 wt%, or 75 wt%, or a range between and including any two of the foregoing values, for example, about 5 wt% to about 30 wt%, about 10 wt% to about 20 wt%, or about 14 wt%.

[0073] The sunscreen compositions and / or coloring cosmetic compositions of this technology can contain a wide range of surfactants. For example, the surfactant can be stearic acid. For example, the composition can contain about 0.05 wt% to about 40 wt% of the total weight of the composition, including about 0.05 wt% to about 20 wt%, about 1 wt% to about 20 wt%, about 2 wt% to about 20 wt%, or about 25 wt% to about 15 wt% of surfactant. In some embodiments, the composition can contain about 1.0 wt%, about 2.0 wt%, about 3.0 wt%, about 4.0 wt%, about 5.0 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, about 10 wt%, about 15 wt%, about 20 wt%, about 40 wt%, or a range between and including any two of the foregoing values.

[0074] The sunscreen compositions and / or coloring cosmetic compositions of this technology may contain a wide range of amounts of the neutralizing agent 3-amino-3-methyl-2-butanol described herein. For example, the composition may contain 3-amino-3-methyl-2-butanol in amounts from about 0.005 wt% to about 10 wt% based on the total weight of the composition, such as about 0.01 wt% to about 10 wt%, about 0.05 wt% to about 8 wt%, about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 3 wt%, about 0.05 wt% to about 2 wt%, about 0.02 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.1 wt% to about 20 wt%, about 0.1 wt% to about 5 wt%, about 0.4 wt% to about 3 wt%, about 0.2 wt% to about 2 wt%, about 0.1 wt% to about 1 wt%, about 0.2 wt% to about 0.3 wt%, about 0.5 wt% to about 10 wt%, or any value or subrange thereof. In some embodiments, the composition may comprise about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, or about 10 wt%, or any two of these values ​​and / or any range between any two of these values. In some embodiments, the composition may comprise about 0.01 wt% to about 0.1 wt% of 3-amino-3-methyl-2-butanol based on the total weight of the composition.

[0075] In addition to 3-amino-3-methyl-2-butanol, the sunscreen compositions and / or coloring cosmetic compositions of this technology may further contain additional neutralizing agents to provide pH balance. The additional neutralizing agent may be selected from triethanolamine, sodium hydroxide, aminomethylpropanol, tromethamine, or combinations of two or more thereof. The additional neutralizing agent may be present in an amount from about 0.005 wt% to about 10 wt%, for example, from about 0.01 wt% to about 0.1 wt%.

[0076] The sunscreen compositions and / or coloring cosmetic compositions of this technology may further comprise moisturizers to draw moisture into the skin and provide skin hydration and moisturizing properties. Illustrative moisturizers include sugar alcohols (e.g., glycerin), polyalkylene glycols (e.g., polyethylene glycol), hydroxyethyl urea, hyaluronic acid, ceramides, glycerin, or any combination of two or more thereof. The moisturizer may be present in amounts from about 0.1 wt% to about 50 wt%, for example, from 0.1 wt% to about 20 wt%, from about 0.1 wt% to about 10 wt%, from about 0.1 wt% to about 5 wt%, from about 1 wt% to about 5 wt%, or from about 3 wt%.

[0077] The sunscreen compositions and / or coloring cosmetic compositions of this technology may contain a wide range of preservatives (e.g., mixtures of benzyl alcohol, ethylhexylglycerin, and tocopherol; and / or Euxyl® PE 9010). For example, the composition may contain preservatives in amounts from about 0.01 wt% to about 10 wt% of the total weight of the composition, including about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.25 wt% to about 0.75 wt%, about 0.35 wt% to about 0.65 wt%, or about 0.4 wt% to about 0.6 wt%. In some embodiments, the composition may contain about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.6 wt%, about 0.7 wt%, about 0.8 wt%, about 0.9 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, or about 5 wt%, or a range between and including any two of the foregoing values.

[0078] The sunscreen compositions and / or coloring cosmetic compositions of this technology can contain a wide range of emollients (e.g., caprylic / capric triglycerides and / or C12-15 alkylbenzoates, silicone oils, and synthetic esters). For example, the composition can contain emollients in amounts from about 0.005 wt% to about 40 wt% of the total weight of the composition, including about 0.05 wt% to about 20 wt%, about 1 wt% to about 20 wt%, about 2 wt% to about 20 wt%, or about 25 wt% to about 15 wt%. In some embodiments, the composition can contain emollients in amounts from about 1.0 wt%, about 2.0 wt%, about 3.0 wt%, about 4.0 wt%, about 5.0 wt%, about 10 wt%, about 15 wt%, about 20 wt%, about 40 wt%, or a range between and including any two of the foregoing values.

[0079] When the sunscreen compositions and / or coloring cosmetic compositions of this technology contain emulsions, the compositions may contain a wide range of emulsifiers. For example, emulsifiers may include ester oils, glyceryl stearate, polysorbate 20, and any combination of two or more thereof disclosed herein.

[0080] Skin lotions, creams, low-pigment and pigment-free cosmetics and similar products In one aspect, this technology provides compositions for skin lotions, creams, low-pigment and pigment-free cosmetics and similar products applied to the skin of the face or body or to the eyelashes or eyebrows. Non-limiting examples of pigment-free and low-pigment cosmetics include various types of mascaras, foundations, lipsticks, blushes, eyeshadows, lip glosses, and eyebrow gels. Low-pigment cosmetics may contain, for example, less than 10 wt%, 5 wt%, 2 wt%, or 1 wt% pigment. Pigment-free and low-pigment cosmetics can be used to create a more natural look, suitable for people who prefer less intense colors or are sensitive to certain pigments. These compositions contain a polymer containing an acidic group, a neutralizing agent (i.e., 3-amino-3-methyl-2-butanol), and a solvent.

[0081] Polymers containing acidic groups can act as thickeners, emulsifiers, stabilizers, film-forming agents, humectants, fixatives, or any combination of two or more thereof. Illustrative polymers containing acidic groups that may be included in the skin care liquid or cream compositions disclosed herein include carbomer, polyacrylic acid, sodium hyaluronate / hyaluronic acid, and acrylic acid copolymers.

[0082] Skin lotions, creams, low-pigment and pigment-free cosmetic compositions of this technology may contain a wide range of amounts of the neutralizing agent 3-amino-3-methyl-2-butanol described herein. For example, the composition may contain 3-amino-3-methyl-2-butanol in amounts from about 0.005 wt% to about 10 wt% based on the total weight of the composition, such as about 0.01 wt% to about 10 wt%, about 0.05 wt% to about 8 wt%, about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 3 wt%, about 0.05 wt% to about 2 wt%, about 0.02 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.1 wt% to about 20 wt%, about 0.1 wt% to about 5 wt%, about 0.4 wt% to about 3 wt%, about 0.2 wt% to about 2 wt%, about 0.1 wt% to about 1 wt%, about 0.2 wt% to about 0.3 wt%, about 0.5 wt% to about 10 wt%, or any value or subrange thereof. In some embodiments, the composition may comprise about 0.005 wt%, about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.15 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.75 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, about 5 wt%, about 6 wt%, about 7 wt%, about 8 wt%, about 9 wt%, or about 10 wt%, or any two of these values ​​and / or any range between any two of these values. In some embodiments, the composition may comprise about 0.1 wt% to about 10 wt% of 3-amino-3-methyl-2-butanol based on the total weight of the composition.

[0083] The skin care lotions, creams, low-pigment, and pigment-free cosmetic compositions of this technology may further include moisturizers to draw moisture into the skin and provide skin hydration and moisturizing properties. Illustrative moisturizers include sugar alcohols (e.g., glycerin), polyalkylene glycols (e.g., polyethylene glycol), hydroxyethyl urea, hyaluronic acid, ceramides, glycerin, or any combination of two or more thereof. The moisturizer may be present in amounts from about 0.1 wt% to about 50 wt%, for example, from about 0.1 wt% to about 20 wt%, from about 0.1 wt% to about 10 wt%, from about 0.1 wt% to about 5 wt%, from about 1 wt% to about 5 wt%, or from about 3 wt%.

[0084] The skin care lotions, creams, low-pigment, and pigment-free cosmetic compositions of this technology can contain a wide range of emollients (e.g., caprylic / capric triglycerides and / or C12-15 alkylbenzoates, coconut oil, olive oil, sunflower oil, avocado oil, almond oil, argan oil, jojoba oil, linseed oil, sesame oil, hemp oil, silicone oil, and synthetic esters). For example, the composition can contain emollients in amounts from about 0.005 wt% to about 40 wt% of the total weight of the composition, including about 0.05 wt% to about 20 wt%, about 1 wt% to about 20 wt%, about 2 wt% to about 20 wt%, or about 25 wt% to about 15 wt%. In some embodiments, the composition may contain about 1.0 wt%, about 2.0 wt%, about 3.0 wt%, about 4.0 wt%, about 5.0 wt%, about 10 wt%, about 15 wt%, about 20 wt%, about 40 wt%, or a range between and including any two of the foregoing values.

[0085] When the skin care lotions, creams, low-pigment, and pigment-free cosmetic compositions of this technology contain emulsions, the compositions may contain a wide range of emulsifiers. For example, emulsifiers may include ester oils, glyceryl stearate, polysorbate 20, and any combination of two or more thereof disclosed herein.

[0086] Skin lotions, creams, low-pigment, and pigment-free cosmetic compositions of this technology can contain a wide range of preservatives (e.g., mixtures of benzyl alcohol, ethylhexylglycerin, and tocopherol; and / or Euxyl® PE 9010). For example, the composition may contain preservatives in amounts from about 0.01 wt% to about 10 wt% of the total weight of the composition, including about 0.05 wt% to about 5 wt%, about 0.05 wt% to about 2 wt%, about 0.05 wt% to about 1 wt%, about 0.25 wt% to about 0.75 wt%, about 0.35 wt% to about 0.65 wt%, or about 0.4 wt% to about 0.6 wt%. In some embodiments, the composition may contain about 0.01 wt%, about 0.05 wt%, about 0.1 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.6 wt%, about 0.7 wt%, about 0.8 wt%, about 0.9 wt%, about 1 wt%, about 1.5 wt%, about 2 wt%, about 3 wt%, about 4 wt%, or about 5 wt%, or a range between and including any two of the foregoing values.

[0087] Methods of manufacturing personal care products The compositions described herein can be manufactured using conventional personal care manufacturing techniques well known to those skilled in the art. Typically, the compositions are manufactured via a two-step process. First, a mixture of some or all of the components of the composition, excluding the neutralizing agent (i.e., AMB), is prepared by mixing (e.g., high-shear stirring to provide a mixture with high viscosity and high solids content). This step of the method aims to form a homogeneous mixture with a stable pH.

[0088] The second step in the method of manufacturing personal care products includes adding an effective amount of a neutralizing agent to neutralize or partially neutralize the acidic components of the composition (e.g., molecules containing acidic groups, such as when the molecules contain polymers containing acidic groups) to achieve a predetermined pH of the composition. In some embodiments, the pH of the composition may be increased to about 5 to about 9 or about 6 to about 8.

[0089] According to any of the foregoing embodiments, this document also provides a method comprising adding an effective amount of 3-amino-3-methyl-2-butanol to a composition comprising a molecule containing an acidic group to increase the pH of the composition, stabilize the composition, and / or at least partially neutralize any acidic group in the composition. Here, at least partially neutralizing the acidic group means adding an amount of 3-amino-3-methyl-2-butanol sufficient to reduce the acidity of the solution such that the pH of the solution increases by at least 0.1 unit, without necessarily reaching a neutralized pH of 7. In some embodiments, the pH of the neutralized composition may be from about 5 to about 9 or from about 6 to about 8. In some embodiments, the composition remains stable for at least about 1 month, at least about 2 months, at least about 3 months, at least about 6 months, at least about 12 months, or at least about 24 months. In some embodiments, 3-methyl-2-butanol neutralizes at least about 20% (e.g., at least about 30%, at least about 40%, or at least about 50%) of the acidic group. In some embodiments, 3-methyl-2-butanol neutralizes about 20% to about 100% (e.g., about 30% to about 90% or about 40% to about 80%) of the acidic groups in the polymer containing acidic groups.

[0090] Unless otherwise specified, a numerical range (e.g., "2 to 10") includes the numerical values ​​that define the range (e.g., 2 and 10).

[0091] Unless otherwise stated, ratios, percentages, parts, etc. are all by weight.

[0092] This document provides embodiments to illustrate the advantages of the present technology and further assist those skilled in the art in preparing or using compositions of the present technology. The embodiments presented herein are also intended to illustrate the present technology more fully. The embodiments should not be construed as limiting the scope of the present technology, which is defined by the appended claims. The embodiments may include or incorporate any variations, aspects, or aspects of the present technology described above. The aforementioned variations, aspects, or aspects may also each further include or incorporate any and all other variations or aspects of the present technology.

[0093] Example General information The IUPAC names and abbreviations of the compounds tested in this paper are provided below.

[0094]

[0095] Example 1. Synthesis of renewable bio-based 3-amino-3-methyl-2-butanol Synthesis of renewable 2-nitropropane (2NP).

[0096] Titanium silicate molecular sieve-1 (5.0 g, TS-1, ACS material), bio-based acetone (29 g, 0.5 mol, Millipore Sigma), and 10% ammonia (170.3 g, 1.0 mol) were placed in a 3-necked flask equipped with a condenser. The mixture was heated to 60–65 °C, and then 35% aqueous hydrogen peroxide solution (145.7 g, 1.5 mol) was added dropwise over a 2-hour period while maintaining the internal temperature of the reaction mixture below 70 °C. After the addition of hydrogen peroxide, the mixture was maintained at 65 °C for 2–4 hours until all intermediate oximes reacted according to GC. The reaction mixture was cooled to room temperature and filtered. 2NPs were separated from the aqueous layer using a separatory funnel and then dried using anhydrous sodium sulfate. The separation yield of 2NPs was 75%, with a purity of 97%.

[0097] Renewable 3-nitro-3-methyl-2-butanol (NMB) and renewable 3-amino-3-methyl-2-butanol (AMB) The synthesis of.

[0098] 2-Nitropropane (1 mol, 97%, from the previous step) and bioacetaldehyde (1 mol, 99%, Millipore Sigma) were added to triethylamine (0.02 mol, Millipore Sigma) in methanol while maintaining the temperature below 50 °C. The mixture was stirred overnight at ambient temperature. GC-FID analysis showed a conversion of 91% from 2NP to NMB. The reaction mixture was then fed into a stainless steel reactor containing Raney nickel (10 wt%) and methanol at 50–80 °C under 650 psi hydrogen. After complete reaction, the mixture was separated from the catalyst and distilled at ambient pressure. The fraction containing the desired product was collected at 158–162 °C and recovered as a colorless liquid. The separation yield was 70%, and the purity was 96% according to GC-FID analysis (capillary column: 30 m fused silica, (5% phenyl)-methylpolysiloxane bonded phase column, inner diameter 0.25 mm and film thickness 1.0 μm; carrier gas flow rate: 1 mL / min helium; gas chromatograph: Agilent model 7890, series II).

[0099] Example 2. Purification and dilution of 3-amino-3-methyl-2-butanol A portion of the product from Example 1 was crystallized from diethyl ether, providing a purity of 99.6%. A dilution was prepared by mixing AMB with deionized water at 40°C. The resulting solution was cooled until the sample solidified. Table 1 below shows the melting point data for AMB samples at different purity levels and dilutions. Sample 1 is the distillation product of Example 1. Sample 2 is Sample 1 with water. Sample 3 is the crystalline form of the product from Example 1. Sample 4 is Sample 3 with water. Higher impurity and water content results in lower melting points.

[0100] Table 1. Properties of 3-amino-3-methyl-2-butanol with different purities and moisture contents

[0101] The separated product can be diluted with water to 90% activity by weight to improve stability.

[0102] Example 3. Preparation and properties of a hair styling aerosol containing 3-amino-3-methyl-2-butanol Prepare the hair styling formulations in Table 2 according to the following schemes: 1. Measure the required amount of solvent: ethanol or ethanol and water.

[0103] 2. Add a fixative polymer.

[0104] 3. Add a neutralizing agent based on the acidity and the required polymer neutralization level, and mix thoroughly.

[0105] 4. Load the required amount of the above concentrate into an aerosol can containing the propellant.

[0106] Composition A is non-aqueous, while composition B contains water.

[0107] Table 2. Exemplary formulations of hair styling aerosols.

[0108] *A blend of isobutane and propane. **1,1-Difluoroethane.

[0109] High humidity curl retention was measured at different time points over a 24-hour period. The high humidity curl retention capability of each exemplary formulation in Table 2 was tested using the following protocol: Prepare a polymer solution of the desired concentration in ethanol.

[0110] Neutralize to 100% using the neutralizing agent under consideration.

[0111] Prepare hair strands for testing. Use freshly washed / conditioned hair strands.

[0112] Apply 0.8 grams of the neutralized polymer solution and comb it onto the hair strands to ensure even distribution of the polymer solution.

[0113] Roll the hair onto the curling iron to set the curl.

[0114] Dry the curls in an explosion-proof oven at 55°C for 15 minutes.

[0115] Make sure your curls are completely dry.

[0116] Remove and hang the curls.

[0117] The length of the curled hair was recorded over time at 30°C and 90% RH.

[0118] Figure 1 The results show that the formulation with AMB performs similarly to the formulation with AMP in terms of maintaining curl over time, and is significantly better than the formulation with TEA and TIPA.

[0119] Example 4. Performance of hair styling gel containing 3-amino-3-methyl-2-butanol The hair styling gels in Table 3 were prepared using the following methods: 1. Measure the required amount of water and add preservative. 2. Add Acudyne or other polymers and mix thoroughly. 3. Add rheology modifier - Aculyn 88 4. Add a neutralizing agent while monitoring the pH, continuing until the desired pH of 7.0-7.5 is reached. 5. If necessary, replenish the remaining water with water. Table 3. Exemplary formulations of hair styling gels using various neutralizing agents.

[0120] *The soft / hard polymers in the emulsion particles contain acrylate / hydroxy acrylate copolymers.

[0121] **Thickeners / rheology modifiers containing acrylate / stearyl alcohol polyether-20 methacrylate crosspolymers.

[0122] ***A cosmetic preservative containing 90 wt% phenoxyethanol and 10 wt% ethylhexylglycerin.

[0123] Compositions C and E are for comparison; composition D according to this technology contains AMB. Figure 2 This indicates that 3-amino-3-methyl-2-butanol behaves similarly to 2-amino-2-methyl-1-propanol and is significantly superior to triethanolamine.

[0124] Example 5. Hand sanitizer formulation containing 3-amino-3-methyl-2-butanol and its performance characteristics. Prepare the hand sanitizers listed in Table 4 as follows: 1. Measure the required amount of water.

[0125] 2. In this case, a rheology modifier - Carbopol 980 - was added. Mix thoroughly until the Carbopol is completely hydrated.

[0126] 3. Add ethanol.

[0127] 4. Add neutralizing agent to pH 7.0-7.2.

[0128] Compositions F, H, I, and K are for comparison purposes; compositions G and J according to this technology contain AMB.

[0129] Table 4. Exemplary formulations of hand sanitizers using various neutralizing agents and 0.25 wt% or 0.45 wt% Carbopol 980 thickener.

[0130] * Rheology modifiers containing cross-linked polyacrylic acid.

[0131] The viscosities of the formulations in Table 4 were measured using a Brookfield viscometer with a spindle RV4 at 6 rpm. The results are shown in Table 5.

[0132] Table 5. Viscosities in centipoise (cP) of hand sanitizer formulations using various neutralizing agents and 0.25 wt% Carbopol 980 (F, G, H) and 0.45 wt% Carbopol 980 (I, J, K).

[0133] Table 4 shows that the formulation containing 3-amino-3-methyl-2-butanol produced a viscosity similar to that of the formulation containing 2-amino-2-methyl-1-propanol, and a significantly higher viscosity than the formulation containing triethanolamine.

[0134] Figure 3A and 3B The results show that formulations containing 3-amino-3-methyl-2-butanol and 0.25 wt% (4A) and 0.45 wt% (4B) Carbopol 980 provide similar clarity to formulations containing 2-amino-2-methyl-1-propanol, and significantly better clarity than formulations containing triethanolamine. Turbidity measurements for these formulations were obtained using an Orion™ AQUAfastAQ3010 turbidimeter and are also shown in Table 5.

[0135] Example 6. Preparation and properties of sunscreen formulations containing 3-amino-3-methyl-2-butanol The five sunscreen formulations in Table 6 were prepared using the following methods: 1. Heat the phases to 75°C and mix thoroughly. 2. Add premixed phase B to phase A, while mixing at 300 rpm and heating at 75°C. 3. Heat phase C separately to 75℃ 4. Add C to A and B, and mix for 1 min using a high-speed mixer at 2000 rpm. Composition LO is for comparison; composition P contains AMB.

[0136] Table 6. Sunscreen formulation

[0137] The SPF of each formulation is measured according to ISO 24443:2021, a standard specifically used to determine the "SPF" sun protection factor. In short, 30 mg of the sunscreen to be tested is applied to a sandblasted polymethyl methacrylate (PMMA) plate with a specific area to achieve 1.2 mg / cm². 2 The dosage was determined. To obtain the most homogeneous film possible, the sample to be tested was applied to the rough phase of the plate using a bare finger pre-saturated with the product. A series of 16 measurements were then performed at 290 to 400 nm using a UV-2600 240V IVDD spectrophotometer (manufacturer: SHIMADZU) or Lambda 1050+ (manufacturer: PERKINELMER) equipped with an integrating sphere. The average absorbance of the measured values ​​was then calculated, thus obtaining the sun protection factor (SPF), UVA, and LOC. The results are shown in... Figure 4The results showed that formulations containing AMB provided the highest SPF rating of any of the tested formulations.

[0138] equivalent While certain embodiments have been described and illustrated, those skilled in the art, upon reading the foregoing specification, can make changes, equivalent substitutions, and other modifications to the composition of the technology set forth herein. Each aspect and embodiment described above may also include or incorporate such changes or aspects disclosed with respect to any or all other aspects and embodiments.

[0139] This technology is not limited to the specific aspects described herein, which are intended as separate illustrations of various aspects of this technology. It will be apparent to those skilled in the art that many modifications and variations can be made to this technology without departing from its spirit and scope. In addition to the methods listed herein, functionally equivalent methods within the scope of this technology will be apparent to those skilled in the art based on the foregoing description. Such modifications and variations are intended to fall within the scope of the appended claims. It should be understood that this technology is not limited to specific methods, reagents, compounds, or compositions, which can, of course, be varied. It should also be understood that the terminology used herein is for the purpose of describing particular aspects only and is not intended to be limiting. Therefore, this specification is intended to be considered merely exemplary, and the breadth, scope, and spirit of this technology are indicated only by the appended claims, the definitions therein, and any equivalents thereof.

[0140] The embodiments described illustratively herein can be suitably implemented without any or more of the elements or limitations specifically disclosed herein. Therefore, terms such as “comprising,” “containing,” and “including” should be interpreted broadly and without limitation. Furthermore, the terms and expressions used herein are used as descriptive rather than restrictive terms, and their use is not intended to exclude any equivalents of the features shown and described or portions thereof, but it should be recognized that various modifications are possible within the scope of the claimed technology. Moreover, the phrase “consistent primarily of…” will be understood to include those specifically listed elements and additional elements that do not substantially affect the essential and novel features of the claimed technology. The phrase “consisting of…” does not include any unspecified elements.

[0141] Furthermore, where features or aspects of this disclosure are described in accordance with the Markush group, those skilled in the art will recognize that this disclosure is also described in accordance with any individual member or subgroup of the Markush group. Each narrower species and subgenus falling within the general scope of the disclosure also constitutes part of this technology. This includes a general description of the technology, with accompanying conditions or negative limitations removing any subject matter from that class, regardless of whether the removed material is specifically described herein.

[0142] As those skilled in the art will understand, for any and all purposes, particularly in providing a written description, all scopes disclosed herein also include any and all possible subscopes and combinations thereof. Any listed scope can be readily considered adequately descriptive and capable of being decomposed into at least equal halves, thirds, quarters, fifths, tenths, etc. As a non-limiting example, each scope discussed herein can be readily decomposed into a lower third, a middle third, and an upper third, etc. Those skilled in the art will also understand that all language, such as “at most,” “at least,” “greater than,” “less than,” etc., includes the listed numbers and refers to scopes that can subsequently be decomposed into subscopes as described above. Finally, those skilled in the art will understand that a scope includes each individual member.

[0143] All publications, patent applications, granted patents, and other documents (e.g., journals, articles, and / or textbooks) mentioned in this specification are incorporated herein by reference as if each individual publication, patent application, granted patent, or other document were specifically and individually indicated to be incorporated herein by reference in its entirety. Definitions contained in the text incorporated by reference are excluded to the extent that they conflict with definitions in this disclosure.

[0144] This technology may include, but is not limited to, the features and combinations of features listed in the following paragraphs. It should be understood that the following paragraphs should not be construed as limiting the scope of the appended claims or requiring that all such features must necessarily be included in these claims: A. A composition comprising: Molecules containing acidic groups; 3-Amino-3-methyl-2-butanol; and Solvent, wherein the solvent optionally includes water and / or alcohol.

[0145] B. The composition of paragraph A, comprising an amount of 3-amino-3-methyl-2-butanol that is effectively partially or completely neutralized by molecules.

[0146] C. The composition of paragraph A, wherein the composition comprises about 0.001 wt% to about 40 wt% of molecules containing acidic groups.

[0147] D. A composition of any of the preceding paragraphs, wherein the composition comprises about 0.01 wt% to about 40 wt% of molecules containing acidic groups.

[0148] E. A composition of any of the preceding paragraphs, wherein the composition comprises about 0.05 wt% to about 15 wt% of molecules containing acidic groups.

[0149] F. A composition of any of the preceding paragraphs, wherein the composition comprises about 0.1 wt% to about 5 wt% of molecules containing acidic groups.

[0150] G. A composition of any of the preceding paragraphs, wherein the composition comprises about 10 wt% to about 30 wt% of molecules containing acidic groups.

[0151] H. A composition of any of the preceding paragraphs, wherein the acidic group of the molecule containing the acidic group is selected from the group consisting of carboxylic acids, sulfonic acids, phosphonic acids, or phosphate groups.

[0152] I. A composition comprising any of the preceding paragraphs, comprising more than one molecule containing an acidic group, each molecule having an acidic group independently selected from the group consisting of: carboxylic acids, sulfonic acids, phosphonic acids, or phosphoric acids, or combinations of two or more thereof.

[0153] J. A composition of any of the preceding paragraphs, wherein the molecule containing an acidic group is a carboxylic acid.

[0154] K. The composition of paragraph A, wherein the molecule containing the acidic group is a polymer containing the acidic group.

[0155] The composition of paragraph K, wherein the polymer is present in an amount of about 0.05 wt% to about 40 wt% of the total weight of the composition.

[0156] M. A composition of paragraph K or paragraph L, wherein the polymer is present in an amount of about 0.1 wt% to about 15 wt% of the total weight of the composition.

[0157] N. A composition of any one of paragraphs K-M0, wherein the polymer is present in an amount of about 0.1 wt% to about 5 wt% of the total weight of the composition.

[0158] O. The composition of paragraph K or paragraph L, wherein the polymer is present in an amount of about 10 wt% to about 30 wt% of the total weight of the composition.

[0159] P. A composition of any one of paragraphs K-O0, wherein the acidic group of the polymer is selected from the group consisting of: carboxyl, sulfonyl, phosphonyl, phosphoryl, or a combination of two or more thereof.

[0160] Q. A composition of any one of paragraphs K-P0, wherein the acidic group of the polymer includes a carboxyl group.

[0161] R. A composition of any one of paragraphs K-Q0, wherein the polymer is selected from the group consisting of: polyacrylate copolymers, vinyl acetate copolymers, or combinations thereof.

[0162] S. A composition of any one of paragraphs K-R0, wherein the polymer is selected from the group consisting of: crosslinked polyacrylic acid; ethyl acrylate, methyl methacrylate and methacrylic acid copolymers; ethyl acrylate, tert-butyl acrylate and methacrylic acid copolymers; octylacrylamide, acrylate and butylaminoethyl methacrylate copolymers; methacrylic acid, n-butyl acrylate and methyl methacrylate copolymers; methacrylic acid, n-butyl acrylate and ethyl methacrylate copolymers; butyl acrylate, methyl methacrylate, hydroxyethyl methacrylate and methacrylic acid copolymers; vinyl acetate, crotonate and neodecanoate vinyl acetate copolymers; butyl ester of vinyl methyl ether and maleic anhydride copolymers; ethyl ester of vinyl methyl ether and maleic anhydride copolymers; vinyl acetate and vinylpyrrolidone copolymers; acrylate / stearyl alcohol polyether-20 methacrylate crosslinked polymers; hyaluronic acid; carbomer; and mixtures of any two or more thereof.

[0163] The composition of any one of paragraphs KS in T. wherein the polymer has a weight-average molecular weight of about 10 to about 1000 kDa.

[0164] U. A composition of any one of paragraphs KT, wherein the polymer is cross-linked.

[0165] V. The composition of any of the preceding paragraphs, wherein 3-amino-3-methyl-2-butanol is present in an amount of about 0.005 wt% to about 10 wt% of the total weight of the composition.

[0166] W. The composition of any of the preceding paragraphs, wherein 3-amino-3-methyl-2-butanol is present in an amount of about 0.02 wt% to about 2 wt% of the total weight of the composition.

[0167] X. A composition of any of the preceding paragraphs, further comprising one or more additives selected from preservatives, thickeners, water-miscible cosolvents, water-immiscible cosolvents, antimicrobial agents, nonionic polymers, dyes, fragrances, and corrosion inhibitors.

[0168] Y. A composition of any of the preceding paragraphs, further comprising anionic and / or amphoteric surfactants.

[0169] Z. The composition of paragraph Y, wherein the anionic and / or zwitterionic surfactant is selected from the group consisting of: fatty acids, alkyl sulfates, alkyl (oxoalkyl) (n) sulfates (where n is an average degree of alkoxylation of 1 to 3), alkyl sulfonates, alkenyl sulfonates, alkyl amides, alkyl betaines, and combinations of two or more thereof.

[0170] AA. The composition of paragraph Y or paragraph Z, wherein the anionic and / or amphoteric surfactant is selected from the group consisting of: sodium lauryl sulfate, ammonium lauryl sulfate, sodium laureth(n) sulfate or ammonium lauryl ether(n) sulfate (where n is an average degree of ethoxylation of 1 to 3), sodium alkoxyalkyl lauryl sulfate, sodium laureth sulfate, cocamidopropyl betaine and combinations of two or more thereof.

[0171] Compositions of any one of paragraphs Y-AA, comprising about 1 wt% to about 50 wt% of anionic and / or amphoteric surfactants.

[0172] A composition of any one of paragraphs Y-AB, comprising about 5 wt% to about 40 wt% of anionic and / or amphoteric surfactants.

[0173] The composition of any one of paragraphs K-AC further comprises an alcohol selected from ethanol, n-propanol, isopropanol, or a combination of two or more thereof.

[0174] The composition of paragraph AD contains about 40 wt% to about 95 wt% alcohol.

[0175] AF. A composition of paragraph AD or paragraph AE, comprising about 60 wt% to about 70 wt% of an alcohol.

[0176] AG. A composition comprising any one of paragraphs AD to AF, comprising about 0.1 wt% to about 1 wt% of a polymer and about 0.02 wt% to about 0.3 wt% of 3-amino-3-methyl-2-butanol.

[0177] The composition of any one of paragraphs K-AG in AH further comprises an acrylate / stearyl alcohol polyether-20 methacrylate crosspolymer thickener, and wherein the polymer is an acrylate / hydroxy acrylate copolymer.

[0178] The composition of AI. paragraph AH comprises about 0.5 wt% to about 4 wt% of a polymer, about 0.1 wt% to about 1 wt% of 3-amino-3-methyl-2-butanol and about 1 wt% to about 10 wt% of a thickener.

[0179] A composition comprising any one of paragraphs K-AI, comprising about 2 wt% to about 15 wt% of a polymer and about 0.4 wt% to about 3 wt% of 3-amino-3-methyl-2-butanol, wherein the polymer is an acrylate / hydroxy acrylate copolymer.

[0180] The composition of AK. paragraph AJ further comprises a propellant.

[0181] AL. The composition of paragraph AK, wherein the propellant is selected from the group consisting of methyl acetate, dimethyl ether, propane, n-butane, isobutane, and mixtures of two or more thereof.

[0182] The composition of any one of paragraphs AJ-AL, comprising about 10 wt% to about 90 wt% ethanol.

[0183] AN. A composition of any of the preceding paragraphs, wherein the composition comprises about 40 wt% to about 60 wt% water and has a pH of about 6 to about 8.

[0184] Compositions of any one of paragraphs K-AI, further comprising about 2 wt% to about 75 wt% pigment.

[0185] AP. Paragraph AO compositions, wherein the pigments include titanium dioxide, zinc oxide, or combinations thereof.

[0186] AQ. A composition comprising about 2 wt% to about 15 wt% of a polymer and about 0.02 wt% to about 2 wt% of 3-amino-3-methyl-2-butanol.

[0187] AR. The composition of any of the preceding paragraphs, wherein the composition further comprises an amino alcohol other than 3-amino-3-methyl-2-butanol.

[0188] AS. The composition of any of the preceding paragraphs, wherein the amino alcohol is 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof.

[0189] A composition of paragraph AR or paragraph AS, wherein the composition contains at least about 0.01 wt% of an amino alcohol.

[0190] AU. A composition of any one of paragraphs AR-AT, wherein the composition comprises 3-(ethylamino)-3-methylbut-2-ol in addition to 3-amino-3-methyl-2-butanol.

[0191] AV. The composition of any of the preceding paragraphs, wherein the composition shows at least about 10% bio-based content as determined by radiocarbon analysis according to ASTM D6866-24.

[0192] AW. The composition of any of the preceding paragraphs, wherein the composition comprises about 0.001 wt% to about 0.5 wt% of a secondary amine.

[0193] AX. The composition of any of the preceding paragraphs, wherein the composition is a hair styling aerosol, body lotion, mascara, hair coloring agent, sunscreen, hand sanitizer, cleanser, eye cream, exfoliant, shampoo, conditioner, hair mask, hair styling gel, hair styling mousse, dry shampoo, non-aerosol hair styling spray, shower gel, soap, body scrub, body butter, lipstick, foundation, eyeshadow, concealer, blush, eyeliner, eyebrow gel, lip gloss, lipstick, setting spray, or shaving cream.

[0194] AY. A method for preparing a composition of any one of paragraphs AJ, the method comprising combining 3-amino-3-methyl-2-butanol of a purity of at least 95 wt% with a molecule containing an acidic group and sufficient water to provide a composition.

[0195] AZ. Paragraph AY's method, wherein the method further includes mixing the combined 3-amino-3-methyl-2-butanol, the molecule containing the acidic group, and water until a homogeneous solution is obtained.

[0196] BA. A composition for use in personal care products, the composition comprising 3-Amino-3-methyl-2-butanol, approximately 30 wt% to approximately 99.99 wt%; Water, approximately 0.01 wt% to approximately 70 wt%; and Optionally, amino alcohols other than 3-amino-3-methyl-2-butanol (“other amino alcohols”).

[0197] Paragraph BB. BA describes compositions for use in hair styling aerosols, body lotions, mascaras, hair colorants, sunscreens, hand sanitizers, cleansers, eye creams, exfoliants, shampoos, conditioners, hair masks, hair styling gels, hair styling mousses, dry shampoos, non-aerosol hair styling sprays, shower gels, soaps, body scrubs, body butters, lipsticks, foundations, eyeshadows, concealers, blushes, eyeliners, eyebrow gels, lip glosses, lipsticks, setting sprays, and / or shaving creams.

[0198] Compositions for use in paragraphs BA or BB, comprising about 0.01 wt% to about 60 wt% of other amino alcohols.

[0199] The composition used in paragraph BC of paragraph BD contains no more than 1 wt% of other amino alcohols.

[0200] BE. A composition for use in any one of paragraphs BA-BD, comprising about 70 wt% to about 95 wt% of 3-amino-3-methyl-2-butanol and about 5 wt% to about 30 wt% of water.

[0201] BF. A composition for use in any of paragraphs BA-BE, comprising about 90 wt% 3-amino-3-methyl-2-butanol, about 10 wt% water and less than 1 wt% other amino alcohols.

[0202] BG. A composition for use in any of paragraphs BA-BF, wherein the composition contains less than 2 wt% of a secondary amine.

[0203] BH. A composition for use in any of paragraphs BA-BG, wherein the composition further comprises no more than 5 wt% of other amino alcohols.

[0204] BI. A composition for use of any one of paragraphs BA-BH, wherein the composition further comprises not more than 0.5 wt% of other amino alcohols.

[0205] BJ. A composition for use in any of paragraphs BA-BI, wherein the other amino alcohol is 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof.

[0206] Compositions for use in any of paragraphs BK-BA-BJ, wherein the composition comprises at least about 0.01 wt% of other amino alcohols.

[0207] BL. A composition for use in any of paragraphs BA-BK, wherein the composition comprises 3-(ethylamino)-3-methylbut-2-ol in addition to 3-amino-3-methyl-2-butanol.

[0208] BM. Any composition for use in paragraphs BA-BL, wherein the composition shows at least about 10% bio-based content as determined by radiocarbon analysis according to ASTM D6866-24.

[0209] The appended claims set forth other embodiments, together with the full range of equivalents that are entitled to by these claims.

Claims

1. A composition comprising: Molecules containing acidic groups; 3-Amino-3-methyl-2-butanol; and Solvent, wherein the solvent optionally includes water and / or alcohol.

2. The composition according to claim 1, wherein the composition comprises an amount of 3-amino-3-methyl-2-butanol that effectively partially or completely neutralizes the molecule.

3. The composition of claim 1, wherein the composition comprises about 0.001 wt% to about 40 wt% of the molecule containing the acidic group.

4. The composition of claim 1, wherein the composition comprises about 0.01 wt% to about 40 wt% of the molecule containing the acidic group.

5. The composition of claim 1, wherein the composition comprises about 0.05 wt% to about 15 wt% of the molecule containing the acidic group.

6. The composition of claim 1, wherein the composition comprises about 0.1 wt% to about 5 wt% of the molecule containing the acidic group.

7. The composition of claim 1, wherein the composition comprises about 10 wt% to about 30 wt% of the molecule containing the acidic group.

8. The composition according to claim 1, wherein the acidic group of the molecule containing the acidic group is selected from carboxylic acid, sulfonic acid, phosphonic acid or phosphate group.

9. The composition according to claim 1, wherein the composition comprises more than one molecule containing an acidic group, each molecule having an acidic group independently selected from: carboxylic acids, sulfonic acids, phosphonic acids or phosphoric acids or combinations of two or more thereof.

10. The composition according to claim 1, wherein the molecule containing the acidic group is a carboxylic acid.

11. The composition according to claim 1, wherein the molecule containing the acidic group is a polymer containing the acidic group.

12. The composition of claim 11, wherein the polymer is present in an amount of about 0.05 wt% to about 40 wt% of the total weight of the composition.

13. The composition of claim 11, wherein the polymer is present in an amount of about 0.1 wt% to about 15 wt% of the total weight of the composition.

14. The composition of claim 11, wherein the polymer is present in an amount of about 0.1 wt% to about 5 wt% of the total weight of the composition.

15. The composition of claim 11, wherein the polymer is present in an amount of about 10 wt% to about 30 wt% of the total weight of the composition.

16. The composition of claim 11, wherein the acidic group of the polymer is selected from carboxyl, sulfonyl, phosphonyl, phosphoryl, or a combination of two or more thereof.

17. The composition of claim 11, wherein the acidic groups of the polymer include carboxyl groups.

18. The composition of claim 11, wherein the polymer is selected from polyacrylate copolymers, vinyl acetate copolymers, or combinations thereof.

19. The composition of claim 11, wherein the polymer is selected from crosslinked polyacrylic acid; ethyl acrylate, methyl methacrylate and methacrylic acid copolymers; ethyl acrylate, tert-butyl acrylate and methacrylic acid copolymers; octylacrylamide, acrylate and butylaminoethyl methacrylate copolymers; methacrylic acid, n-butyl acrylate and methyl methacrylate copolymers; methacrylic acid, n-butyl acrylate and ethyl methacrylate copolymers; butyl acrylate, methyl methacrylate, hydroxyethyl methacrylate and methacrylic acid copolymers; vinyl acetate, crotonate and neodecanoate vinyl acetate copolymers; butyl ester of vinyl methyl ether and maleic anhydride copolymers; ethyl ester of vinyl methyl ether and maleic anhydride copolymers; vinyl acetate and vinylpyrrolidone copolymers; acrylate / stearyl alcohol polyether-20 methacrylate crosslinked polymers; hyaluronic acid; carbomer; and mixtures of any two or more thereof.

20. The composition of claim 11, wherein the polymer has a weight-average molecular weight of about 10 to about 1000 kDa.

21. The composition of claim 11, wherein the polymer is crosslinked.

22. The composition according to claim 1, wherein 3-amino-3-methyl-2-butanol is present in an amount of about 0.005 wt% to about 10 wt% of the total weight of the composition.

23. The composition according to claim 1, wherein 3-amino-3-methyl-2-butanol is present in an amount of about 0.02 wt% to about 2 wt% of the total weight of the composition.

24. The composition of claim 1, further comprising one or more additives selected from preservatives, thickeners, water-miscible cosolvents, water-immiscible cosolvents, antimicrobial agents, nonionic polymers, dyes, fragrances, and corrosion inhibitors.

25. The composition according to claim 1, wherein the composition further comprises anionic and / or amphoteric surfactants.

26. The composition according to claim 25, wherein the anionic and / or zwitterionic surfactant is selected from fatty acids; alkyl sulfates; alkyl (oxoalkyl) (n) sulfates, wherein n is an average degree of alkoxylation of 1 to 3; alkyl sulfonates; alkenyl sulfonates; alkyl amides; alkyl betaines; and combinations of two or more thereof.

27. The composition according to claim 25, wherein the anionic and / or amphoteric surfactant is selected from sodium lauryl sulfate; ammonium lauryl sulfate; sodium laureth(n) sulfate or ammonium lauryl ether(n) sulfate, wherein n is an average degree of ethoxylation of 1 to 3; alkoxyalkyl sodium lauryl sulfate; sodium lauryl ether sulfate; cocamidopropyl betaine; and combinations of two or more thereof.

28. The composition of claim 25, wherein the composition comprises about 1 wt% to about 50 wt% of the anionic and / or amphoteric surfactant.

29. The composition of claim 25, wherein the composition comprises about 5 wt% to about 40 wt% of the anionic and / or amphoteric surfactant.

30. The composition of claim 11, wherein the composition further comprises an alcohol selected from ethanol, n-propanol, isopropanol, or a combination of two or more thereof.

31. The composition of claim 30, wherein the composition comprises about 40 wt% to about 95 wt% of the alcohol.

32. The composition of claim 30, wherein the composition comprises about 60 wt% to about 70 wt% of the alcohol.

33. The composition of claim 30, wherein the composition comprises about 0.1 wt% to about 1 wt% of a polymer and about 0.02 wt% to about 0.3 wt% of 3-amino-3-methyl-2-butanol.

34. The composition of claim 11, further comprising an acrylate / stearyl alcohol polyether-20 methacrylate crosslinking polymer thickener, wherein the polymer is an acrylate / hydroxy acrylate copolymer.

35. The composition of claim 34, wherein the composition comprises about 0.5 wt% to about 4 wt% of the polymer, about 0.1 wt% to about 1 wt% of 3-amino-3-methyl-2-butanol and about 1 wt% to about 10 wt% of a thickener.

36. The composition of claim 11, wherein the composition comprises about 2 wt% to about 15 wt% of the polymer and about 0.4 wt% to about 3 wt% of 3-amino-3-methyl-2-butanol, and wherein the polymer is an acrylate / hydroxy acrylate copolymer.

37. The composition of claim 36, wherein the composition further comprises a propellant.

38. The composition of claim 37, wherein the propellant is selected from methyl acetate, dimethyl ether, propane, n-butane, isobutane, and mixtures of two or more thereof.

39. The composition of claim 36, wherein the composition further comprises about 10 wt% to about 90 wt% ethanol.

40. The composition of claim 1, wherein the composition comprises about 40 wt% to about 60 wt% water and has a pH of about 6 to about 8.

41. The composition of claim 11, wherein the composition further comprises about 2 wt% to about 75 wt% of pigment.

42. The composition of claim 41, wherein the pigment comprises titanium dioxide, zinc oxide, or a combination thereof.

43. The composition of claim 41, wherein the composition comprises about 2 wt% to about 15 wt% of the polymer and about 0.02 wt% to about 2 wt% of 3-amino-3-methyl-2-butanol.

44. The composition of claim 1, wherein the composition further comprises an amino alcohol other than 3-amino-3-methyl-2-butanol.

45. The composition according to claim 44, wherein the amino alcohol is 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof.

46. ​​The composition of claim 44, wherein the composition comprises at least about 0.01 wt% of the amino alcohol.

47. The composition according to claim 44, wherein, in addition to 3-amino-3-methyl-2-butanol, the composition comprises 3-(ethylamino)-3-methylbut-2-ol.

48. The composition of claim 1, wherein the composition exhibits at least about 10% bio-based content as determined by radiocarbon analysis according to ASTM D6866-24.

49. The composition of claim 1, wherein the composition comprises about 0.001 wt% to about 0.5 wt% of a secondary amine.

50. The composition of claim 1, wherein the composition is a hair styling aerosol, body lotion, mascara, hair coloring agent, sunscreen, hand sanitizer, cleanser, eye cream, exfoliant, shampoo, conditioner, hair mask, hair styling gel, hair styling mousse, dry shampoo, non-aerosol hair styling spray, shower gel, soap, body scrub, body butter, lipstick, eyebrow gel, foundation, concealer, blush, eyeshadow, eyeliner, lip gloss, lipstick, setting spray, or shaving cream.

51. A method for preparing the composition according to claim 1, the method comprising combining 3-amino-3-methyl-2-butanol of a purity of at least 95 wt% with a molecule containing an acidic group and sufficient water to provide the composition.

52. The method of claim 50, wherein the method further comprises mixing the combined 3-amino-3-methyl-2-butanol, the molecule containing the acidic group, and water until a homogeneous solution is obtained.

53. A composition for use in a personal care product, said composition comprising 3-Amino-3-methyl-2-butanol, approximately 50 wt% to approximately 99.99 wt%; Water, approximately 0.01 wt% to approximately 50 wt%; and Optionally, amino alcohols other than 3-amino-3-methyl-2-butanol ("other amino alcohols").

54. The composition for use according to claim 53, wherein the composition is intended for use in hair styling aerosols, body lotions, mascaras, hair colorants, sunscreens, hand sanitizers, cleansers, eye creams, exfoliants, shampoos, conditioners, hair masks, hair styling gels, hair styling mousses, dry shampoos, non-aerosol hair styling sprays, shower gels, soaps, body scrubs, body butters, lipsticks, foundations, eyeshadows, concealers, blushes, eyeliners, eyebrow gels, lip glosses, lipsticks, setting sprays, and / or shaving creams.

55. The composition for use according to claim 53, wherein the composition comprises about 0.01 wt% to about 60 wt% of the other amino alcohol.

56. The composition for use according to claim 55, wherein the composition comprises no more than 1 wt% of the other amino alcohol.

57. The composition for use according to claim 53, wherein the composition comprises about 70 wt% to about 95 wt% of 3-amino-3-methyl-2-butanol and about 5 wt% to about 30 wt% of water.

58. The composition for use according to claim 53, wherein the composition comprises about 90 wt% of 3-amino-3-methyl-2-butanol, about 10 wt% of water and less than 1 wt% of the other amino alcohols.

59. The composition for use according to claim 53, wherein the composition comprises less than 2 wt% of a secondary amine.

60. The composition for use according to claim 53, wherein the composition further comprises no more than 5 wt% of the other amino alcohol.

61. The composition for use according to claim 53, wherein the composition further comprises no more than 0.5 wt% of the other amino alcohol.

62. The composition for use according to claim 61, wherein the other amino alcohol is 2-aminoethanol, triethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, 2-amino-1-butanol, 2-amino-2-ethyl-1,3-propanediol, 3-(ethylamino)-3-methylbut-2-ol, or any combination of two or more thereof.

63. The composition for use according to claim 61, wherein the composition comprises at least about 0.01 wt% of the other amino alcohol.

64. The composition for use according to claim 61, wherein, in addition to 3-amino-3-methyl-2-butanol, the composition comprises 3-(ethylamino)-3-methylbut-2-ol.

65. The composition for use according to claim 53, wherein the composition shows at least about 10% bio-based content as determined by radiocarbon analysis according to ASTM D6866-24.

Images