Personal care composition

By using specific proportions of ingredients such as vitamin E, vitamin B, and amaranth extract in personal care compositions, the problem of complex and ineffective ingredients has been solved, achieving antioxidant and skin health benefits with simplified ingredients and enhancing the skin's self-repair ability.

CN122121847APending Publication Date: 2026-05-29COLGATE PALMOLIVE CO

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
COLGATE PALMOLIVE CO
Filing Date
2024-08-22
Publication Date
2026-05-29

AI Technical Summary

Technical Problem

Existing skin health products often have complex ingredients and poor efficacy, making it difficult to provide significant antioxidant and skin health benefits while simplifying the ingredients.

Method used

A personal care composition is provided comprising a specific ratio of vitamin E, vitamin B, amaranth plant extract, polysaccharides, fatty alcohols, and short-chain fatty acids to enhance antioxidant effects and maintain gentleness on the skin.

Benefits of technology

It achieves significant antioxidant and skin health benefits while simplifying the ingredients, reducing the damage of reactive oxygen species to the skin, and enhancing the skin's self-repair ability.

✦ Generated by Eureka AI based on patent content.

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Abstract

Disclosed herein are personal care compositions having enhanced antioxidant efficacy and are mild to the skin. According to one aspect, there is provided a personal care composition having from about 0.1 to about 9 wt.% of vitamin E, the vitamin E comprising tocopherols; from about 1 to about 10 wt.% of vitamin B, the vitamin B comprising nicotinamide; and an extract of Amaranthus sp., wherein all weight percents are based on the total weight of the personal care composition.
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Description

Cross-references to related applications

[0001] This application claims priority to U.S. Patent Application No. 63 / 520,962, filed August 22, 2023, entitled “Personal Care Compositions,” the contents of which are incorporated herein by reference in their entirety for all purposes. Background Technology

[0002] Reactive oxygen species (ROS) are free radicals that can react with various cellular proteins in the skin, such as collagen, elastin, and glycosaminoglycans. ROS cause collagen and elastin to cross-link, leading to wrinkles and reducing the skin's self-repair ability. Therefore, ROS-induced skin damage can contribute to physiological aging or lead to skin conditions. Antioxidants can eliminate and reduce excess ROS production and mitigate its damage to cells in various tissues, including the skin.

[0003] Furthermore, in the skin health sector, recent consumer trends demand products that are as simple as possible, yet still provide the acceptable skin health benefits that consumers are already accustomed to from products containing multiple ingredients. However, when using fewer ingredients, there is a greater focus on maximizing the effects and efficacy of each ingredient to provide consumers with antioxidant and skin health benefits.

[0004] Therefore, there is a need for a skin health product that is simple yet can provide or exceed the skin health benefits found in products containing multiple ingredients that claim to have skin health benefits. Summary of the Invention

[0005] This invention is intended only to provide a simplified overview of some aspects of one or more embodiments of the present disclosure. Further areas of application of the present disclosure will become apparent from the detailed embodiments provided below. This invention is not a broad review, nor is it intended to identify key or essential elements of the teachings, nor to depict the scope of the disclosure. Rather, its purpose is merely to present one or more concepts in a simplified form as a prelude to the detailed embodiments described below.

[0006] According to one aspect of the invention, a personal care composition is provided having about 0.1 to about 9 wt.% vitamin E, said vitamin E comprising tocopherol; about 1 to about 10 wt.% vitamin B, said vitamin B comprising nicotinamide; and an amaranth extract, wherein all weight percentages are based on the total weight of said personal care composition.

[0007] According to another aspect of the invention, a personal care composition is provided having about 0.01 to about 5 wt.% polysaccharides; about 0.01 to about 12 wt.% fatty alcohols; about 0.05 to about 7 wt.% short-chain fatty acids; about 0.1 to about 9 wt.% vitamin E; about 1 to about 10 wt.% vitamin B; and amaranth plant extract, wherein all weight percentages are based on the total weight of the personal care composition.

[0008] According to another aspect of the invention, a personal care composition is provided having about 0.01 to about 5 wt.% polysaccharides; about 0.01 to about 12 wt.% fatty alcohols; about 0.05 to about 7 wt.% short-chain fatty acids; about 0.1 to about 9 wt.% vitamin E; about 1 to about 10 wt.% vitamin B; and about 0.1 to about 8 wt.% vitamin C, wherein all weight percentages are based on the total weight of the personal care composition.

[0009] The following is a list of non-limiting exemplary embodiments according to certain aspects of the present invention.

[0010] According to embodiment 1, a personal care composition is provided, comprising: About 0.1 to about 9 wt.% of vitamin E, said vitamin E comprising tocopherol; About 1 to about 10 wt.% of vitamin B, said vitamin B comprising nicotinamide; and Amaranth plant extracts, All weight percentages are based on the total weight of the personal care composition.

[0011] According to embodiment 2, a personal care composition according to embodiment 1 is provided, which further comprises about 0.05 to about 8 wt.% vitamin C.

[0012] According to embodiment 3, a personal care composition according to embodiment 2 is provided, wherein the vitamin C is selected from ascorbyl glucoside, ascorbate-2-glucoside, ascorbate acetate, tetrahexyldecyl ascorbate, and combinations of two or more thereof.

[0013] According to embodiment 4, a personal care composition according to embodiment 2 or embodiment 3 is provided, wherein the vitamin C comprises tetrahexyldecyl ascorbate.

[0014] According to embodiment 5, a personal care composition according to embodiment 4 is provided, wherein the amount of tetrahexyldecyl ascorbate is from about 0.05 to about 1 wt.%.

[0015] According to embodiment 6, a personal care composition according to any of the foregoing embodiments is provided, wherein the amaranth extract is present in an amount of about 0.05 to about 5 wt.%.

[0016] According to embodiment 7, a personal care composition according to any of the foregoing embodiments is provided, wherein the personal care composition has a weight ratio of α-tocopherol to nicotinamide of about 1:1 to about 1:11.

[0017] According to embodiment 8, a personal care composition according to any of the foregoing embodiments is provided, which further comprises one or more short-chain fatty acids and / or their salts.

[0018] According to embodiment 9, a personal care composition according to embodiment 8 is provided, wherein one or more short-chain fatty acids and / or their salts comprise short-chain fatty acids having 1 to 5 carbons.

[0019] According to embodiment 10, a personal care composition according to embodiment 8 or embodiment 9 is provided, wherein the one or more short-chain fatty acids and / or their salts are selected from pentanoic acid, CH3CH2CH2CH2COOH, isovaleric acid, 3-methylbutyric acid, (CH3)2CHCH2COOH, 2-methylpropionic acid, (CH3)2CHCOOH, butanoic acid, CH3CH2CH2COOH, CH3CH2COOH, ethanoic acid, CH3COOH, formic acid, HCOOH, acetic acid, succinic acid, succinic acid, formic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, isovaleric acid, lactic acid, pyruvic acid, derivatives thereof, salts thereof, and combinations of two or more thereof.

[0020] According to embodiment 11, a personal care composition according to any one of embodiments 8 to 10 is provided, wherein the total amount of the one or more short-chain fatty acids and / or their salts is about 0.05 to about 7 wt.%.

[0021] According to embodiment 12, a personal care composition according to any of the foregoing embodiments is provided, which further comprises about 0.05 to about 10 wt.% polysaccharides.

[0022] According to embodiment 13, a personal care composition according to embodiment 12 is provided, wherein the polysaccharide is selected from cellulose, carboxymethyl hydroxyethyl cellulose, cellulose acetate propionate carboxylate, hydroxyethyl cellulose, hydroxyethyl ethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, methyl hydroxyethyl cellulose, microcrystalline cellulose, sodium cellulose sulfate, gum arabic, agar, alginate, alginic acid, ammonium alginate, amylopectin, calcium alginate, calcium carrageenan, carnitine, carrageenan, dextrin, gelatin, gellan gum, guar gum, guar hydroxypropyltrimethylammonium chloride, lithium montmorillonite, hyaluronic acid, hydrated silica, hydroxypropyl chitosan, hydroxypropyl guar gum, kelp gum, locust bean gum, natto gum, potassium alginate, potassium carrageenan, propylene glycol alginate, sclerotium gluconate. gum), sodium carboxymethyl dextran, carrageenan, tragacanth gum, xanthan gum, biosaccharide gum, inulin, and combinations thereof.

[0023] According to embodiment 14, a personal care composition according to embodiment 12 or embodiment 13 is provided, wherein the polysaccharide comprises inulin, carrageenan, galactooligosaccharide, fructooligosaccharide, α-glucan, β-glucan, or a combination thereof.

[0024] According to embodiment 15, a personal care composition according to any one of embodiments 12 to 14 is provided, wherein the polysaccharide comprises inulin.

[0025] According to embodiment 16, a personal care composition according to any of the foregoing embodiments is provided, which further comprises about 0.01 to about 12 wt.% fatty alcohol.

[0026] According to embodiment 17, a personal care composition according to embodiment 16 is provided, wherein the fatty alcohol comprises butyloctanol.

[0027] According to embodiment 18, a personal care composition according to embodiment 17 is provided, wherein the butyloctanol is 2-butyloctanol.

[0028] According to embodiment 19, a personal care composition according to any of the foregoing embodiments is provided, which further comprises hyaluronic acid and / or its salts.

[0029] According to embodiment 20, a personal care composition according to embodiment 19 is provided, wherein the hyaluronic acid and / or its salts have an average molecular weight of about 1 Mda to about 4 Mda.

[0030] According to embodiment 21, a personal care composition according to embodiment 19 or embodiment 20 is provided, wherein the hyaluronic acid and / or its salts are present in an amount of about 0.05 to about 5 wt.%.

[0031] According to embodiment 22, a personal care composition according to any of the foregoing embodiments is provided, wherein the personal care composition is substantially free of or contains no ergothioneine.

[0032] According to embodiment 23, a personal care composition according to any of the foregoing embodiments is provided, wherein the personal care composition is substantially free of or free of histidine thiourea derivatives.

[0033] According to embodiment 24, a personal care composition according to any of the foregoing embodiments is provided, which further comprises non-short-chain fatty acids.

[0034] According to embodiment 25, a personal care composition according to embodiment 24 is provided, wherein the non-short-chain fatty acids comprise linolenic acid, octadecanoic acid, eicosapentaenoic acid, eicosapentaenoic acid, docosahexaenoic acid, linolenic acid, calendic acid, eicosadienoic acid, arachidonic acid, docosadienoic acid, adrenaline, osbond acid, docosatraenoic acid, docosapentaenoic acid, palmitic acid, palmitoleic acid, stearic acid, oleic acid, isoleic acid, linolenic acid, α-linolenic acid, arachidic acid, or combinations of two or more thereof.

[0035] According to embodiment 26, a personal care composition according to embodiment 25 is provided, wherein the non-short-chain fatty acid comprises an ω-3 fatty acid selected from linolenic acid, octadecanoic acid, eicosapentaenoic acid, eicosapentaenoic acid, docosahexaenoic acid, and combinations of two or more thereof.

[0036] According to embodiment 27, a personal care composition according to embodiment 25 is provided, wherein the non-short-chain fatty acid comprises an ω-6 fatty acid selected from linolenic acid, calendula acid, eicosapentaenoic acid, arachidonic acid, adrenal acid, octoporic acid, docosahexaenoic acid, docosapentaenoic acid, and combinations of two or more thereof.

[0037] According to embodiment 28, a personal care composition according to any one of embodiments 25 to 27 is provided, wherein the non-short-chain fatty acid comprises oleic acid and linolenic acid, wherein the weight ratio of oleic acid to linolenic acid is about 1:1 to about 1:4.

[0038] According to embodiment 29, a personal care composition is provided, comprising: Approximately 0.05 to approximately 5 wt.% polysaccharides; Fatty alcohols: about 0.01 to about 12 wt.%; About 0.05 to about 7 wt.% of short-chain fatty acids and / or their salts; Approximately 0.1 to approximately 9 wt.% of vitamin E; Approximately 1 to approximately 10 wt.% of vitamin B; and Amaranth plant extracts, All weight percentages are based on the total weight of the personal care composition.

[0039] According to embodiment 30, a personal care composition according to embodiment 29 is provided, wherein the vitamin E is selected from the group consisting of: α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, α-tocotrienol, β-tocotrienol, γ-tocotrienol, δ-tocotrienol, tocopherol acetate, tocopherol phosphate, natural extracts rich in vitamin E derivatives, and combinations thereof.

[0040] According to embodiment 31, a personal care composition according to embodiment 29 or embodiment 30 is provided, wherein the vitamin B comprises vitamin B3.

[0041] According to embodiment 32, a personal care composition according to embodiment 31 is provided, wherein the vitamin B3 is selected from nicotinic acid esters, non-vasodilating esters of nicotinic acid, nicotinyl amino acids, nicotinic acid esters of carboxylic acids, nicotinic acid N-oxide, nicotinamide N-oxide, tocopheryl nicotinic acid esters, inositol hexanicotinic acid esters, and combinations of two or more thereof.

[0042] According to embodiment 33, a personal care composition according to any one of embodiments 29 to 32 is provided, which further comprises about 0.05 to about 8 wt.% vitamin C.

[0043] According to embodiment 34, a personal care composition according to embodiment 33 is provided, wherein the vitamin C is selected from ascorbate glucoside, ascorbate-2-glucoside, ascorbate acetate, tetrahexyldecyl ascorbate, and combinations of two or more thereof.

[0044] According to embodiment 35, a personal care composition according to embodiment 33 or embodiment 34 is provided, wherein the vitamin C comprises tetrahexyldecyl ascorbate.

[0045] According to embodiment 36, a personal care composition according to any one of embodiments 29 to 35 is provided, which further comprises hyaluronic acid and / or its salts.

[0046] According to embodiment 37, a personal care composition according to embodiment 36 is provided, wherein the hyaluronic acid and / or its salts have an average molecular weight of about 1 Mda to about 4 Mda.

[0047] According to embodiment 38, a personal care composition according to embodiment 36 or embodiment 37 is provided, wherein the hyaluronic acid and / or its salts are present in an amount of about 0.05 to about 5 wt.%.

[0048] According to embodiment 39, a personal care composition is provided, comprising: Approximately 0.05 to approximately 5 wt.% polysaccharides; Fatty alcohols: about 0.01 to about 12 wt.%; About 0.05 to about 7 wt.% of short-chain fatty acids and / or their salts; Approximately 0.1 to approximately 9 wt.% of vitamin E; Approximately 1 to approximately 10 wt.% of vitamin B; and Approximately 0.05 to approximately 8 wt.% of vitamin C; All weight percentages are based on the total weight of the personal care composition.

[0049] According to embodiment 40, a personal care composition according to embodiment 39 is provided, wherein the vitamin E is selected from the group consisting of: α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, α-tocotrienol, β-tocotrienol, γ-tocotrienol, δ-tocotrienol, tocopherol acetate, tocopherol phosphate, natural extracts rich in vitamin E derivatives, and combinations thereof.

[0050] According to embodiment 41, a personal care composition according to embodiment 39 or embodiment 40 is provided, wherein the vitamin B comprises vitamin B3.

[0051] According to embodiment 42, a personal care composition according to any one of embodiments 39 to 41 is provided, wherein the vitamin B3 is selected from nicotinic acid esters, non-vasodilating esters of nicotinic acid, nicotinic acid amino acids, nicotinic acid esters of carboxylic acids, nicotinic acid N-oxide, nicotinamide N-oxide, tocopheryl nicotinic acid esters, inositol hexanicotinic acid esters, and combinations of two or more thereof.

[0052] According to embodiment 43, a personal care composition according to any one of embodiments 39 to 42 is provided, which further comprises an amaranth plant extract containing a variety of ω-3 fatty acids and / or ω-6 fatty acids.

[0053] According to embodiment 44, a personal care composition according to any one of embodiments 39 to 42 is provided, which further comprises hyaluronic acid and / or its salts.

[0054] According to embodiment 45, a personal care composition according to embodiment 44 is provided, wherein the hyaluronic acid and / or its salts have an average molecular weight of about 1 Mda to about 4 Mda.

[0055] According to embodiment 46, a personal care composition according to embodiment 44 or embodiment 45 is provided, wherein the hyaluronic acid and / or its salts are present in an amount of about 0.05 to about 5 wt.%.

[0056] According to embodiment 47, a personal care composition according to any of the foregoing embodiments is provided, which further comprises about 1 to about 30 wt.% of a polyol.

[0057] According to embodiment 48, a personal care composition according to embodiment 47 is provided, wherein the polyol comprises one or more diols selected from the group consisting of octyl ethylene glycol, isopentyl glycol, ethylene glycol, propylene glycol, butylene glycol, hexanediol, glycerin, diglycerol, diethylene glycol, dipropylene glycol, and combinations of two or more thereof.

[0058] According to embodiment 49, a personal care composition according to any of the foregoing embodiments is provided, which further comprises a soothing agent.

[0059] According to embodiment 50, a personal care composition according to embodiment 49 is provided, wherein the soothing agent comprises bisabolol, aloe vera extract, allantoin, licorice extract, glycyrrhizin, or a combination thereof.

[0060] According to embodiment 51, a personal care composition according to any one of embodiments 29 to 50 is provided, wherein the personal care composition is substantially free of or contains no ergothioneine.

[0061] According to embodiment 52, a personal care composition according to any one of embodiments 29 to 51 is provided, wherein the personal care composition is substantially free of or free of histidine thiourea derivatives. Attached Figure Description

[0062] The invention can be more fully understood from the detailed embodiments and accompanying drawings, wherein the same elements are similarly labeled, and wherein:

[0063] The accompanying drawing is a bar graph illustrating the tactile properties of a non-limiting exemplary composition according to aspects of the present invention.

[0064] It should be understood that the aspects are not limited to the arrangements and tools shown in the accompanying drawings. Detailed Implementation

[0065] For illustrative purposes, the principles of the invention are described by reference to various exemplary embodiments thereof. Although certain embodiments of the invention have been specifically described herein, those skilled in the art will readily recognize that the same principles apply equally to and can be used in other compositions and methods. Before explaining the embodiments disclosed herein in detail, it should be understood that the invention is not limited in its application to the details of any particular embodiment disclosed herein. The terminology used herein is for descriptive purposes and not for limiting purposes.

[0066] As used herein and in the appended claims, the singular forms “a,” “an,” and “the” include plural references unless the context otherwise requires. The singular form of any class of ingredients refers not only to one chemical substance in that class but also to mixtures of such chemical substances. The terms “a” (or “an”), “one or more,” and “at least one” are used interchangeably herein. The terms “comprising,” “including,” and “having” are used interchangeably. The term “include” should be construed as “including, but not limited to.”

[0067] As used throughout, a range is used as a shorthand to describe the individual values ​​within that range. Any value within the range can be chosen as an endpoint. Therefore, the range 1-5 specifically includes 1, 2, 3, 4, and 5, as well as subranges such as 2-5, 3-5, 2-3, 2-4, 1-4, etc. When referring to numbers, the term "about" refers to any number within a 10% range of that number. For example, the phrase "about 2 wt.%" refers to a number between 1.8 wt.% and 2.2 wt.%, inclusive.

[0068] All references cited in this document are incorporated herein by reference in their entirety. In the event of any discrepancy between the definitions in this disclosure and those in the cited references, this disclosure shall prevail.

[0069] The abbreviations and symbols used herein have their ordinary meanings unless otherwise stated. The abbreviation "wt.%" refers to a weight percentage relative to the personal care composition. The symbol "°" refers to degrees, such as temperature or angle. The symbols "hr," "min," "mL," "nm," and "μm" refer to hours, minutes, milliliters, nanometers, and micrometers, respectively. The abbreviation "UV-VIS" refers to a spectrometer or spectroscopy, meaning ultraviolet-visible light. The abbreviation "rpm" indicates revolutions per minute.

[0070] As used in this article, "volatile" means having a flash point of less than about 100°C. As used in this article, "non-volatile" means having a flash point of greater than about 100°C.

[0071] When referring to chemical structures and names, the symbols "C", "H", and "O" represent carbon, hydrogen, and oxygen, respectively. The symbols "-", "=", and "≡" represent single, double, and triple bonds, respectively.

[0072] Any member of a species list used to exemplify or define a genus may be distinct from, overlap with, be a subset of, be equivalent to, or be nearly identical to, or be the same as any other member of that genus. Furthermore, for example, when listing the Markush group, the species list defining or defining the genus is open-ended and assumes the existence of other species that define or define the genus as well as, or better than, any other species listed, unless explicitly stated otherwise.

[0073] The phrases “mixtures thereof,” “combinations thereof,” or “combinations of two or more thereof” do not require that the mixture include all of A, B, C, D, E, and F (although it may include all of A, B, C, D, E, and F). Rather, it indicates a mixture that may include any two or more of A, B, C, D, E, and F. In other words, it is equivalent to the phrase “one or more elements selected from the group consisting of A, B, C, D, E, F, and mixtures of any two or more of A, B, C, D, E, and F.” Similarly, the term “a salt thereof” also refers to “salts thereof.” Therefore, when this disclosure refers to "an element selected from the group consisting of A, B, C, D, E, F, their salts and mixtures thereof", it means that it may include one or more of A, B, C, D and F, one or more of the salts of A, B, C, D, E and F, or a mixture of any two of the salts of A, B, C, D, E, F, the salts of A, B, C, D, E and F.

[0074] All components and elements positively described in this disclosure may be negatively excluded from the claims. In other words, the personal care compositions of this disclosure may be free of or substantially free of all components and elements positively described throughout this disclosure. In some cases, the personal care compositions of this disclosure may be substantially free of non-accidental amounts of the ingredients or compounds described herein. A non-accidental amount of an ingredient or compound is the amount of an ingredient or compound added alone to the personal care composition. For example, a personal care composition may be substantially free of non-accidental amounts of an ingredient or compound, although such an ingredient or compound may be present as part of a raw material contained as a blend of two or more compounds.

[0075] Some of the components in the defined categories may overlap. In cases where overlap is possible and the personal care composition contains two components (or more than two overlapping components), the overlapping compounds do not represent more than one component. For example, some compounds may be characterized as polysaccharides and thickeners. If a particular personal care composition contains and / or lists both polysaccharides and thickeners, a compound that can be characterized as both a polysaccharide and a thickener will only act as a polysaccharide or a thickener, not both.

[0076] For readability purposes, chemical functional groups are given their adjectival forms; for each adjective, the word "group" is assumed. For example, the adjective "alkyl" without a noun should be read as "alkyl group".

[0077] This invention relates to personal care compositions that have enhanced antioxidant efficacy and are gentle on the skin. The inventors have discovered that certain components and / or ingredients in specific amounts and proportions of a personal care composition can achieve significant improvements in reducing reactive oxygen species while maintaining gentleness on the skin.

[0078] According to one aspect of the invention, a personal care composition is provided having about 0.1 to about 9 wt.% vitamin E, said vitamin E comprising tocopherol; about 1 to about 10 wt.% vitamin B, said vitamin B comprising nicotinamide; and an amaranth plant extract, wherein all weight percentages are based on the total weight of said personal care composition.

[0079] According to another aspect of the invention, a personal care composition is provided having about 0.01 to about 5 wt.% polysaccharides; about 0.01 to about 12 wt.% fatty alcohols; about 0.05 to about 7 wt.% short-chain fatty acids; about 0.1 to about 9 wt.% vitamin E; about 1 to about 10 wt.% vitamin B; and amaranth plant extract, wherein all weight percentages are based on the total weight of the personal care composition.

[0080] According to a further part of the invention, a personal care composition is provided having about 0.01 to about 5 wt.% polysaccharides; about 0.01 to about 12 wt.% fatty alcohols; about 0.05 to about 7 wt.% short-chain fatty acids; about 0.1 to about 9 wt.% vitamin E; about 1 to about 10 wt.% vitamin B; and about 0.1 to about 8 wt.% vitamin C, wherein all weight percentages are based on the total weight of the personal care composition.

[0081] In some embodiments, the personal care composition may be formulated to have a limited amount of ergothioneine, substantially free of or without it. For example, the amount of ergothioneine in the personal care composition may be about 2 wt.% or less, about 1 wt.% or less, about 0.5 wt.% or less, about 0.1 wt.% or less, about 0.05 wt.% or less, or about 0.01 wt.% or less, based on the total weight of the personal care composition. In at least one embodiment, the personal care composition has about 0 or 0 wt.% ergothioneine.

[0082] Additionally or alternatively, the personal care composition may be formulated having a limited amount of a thiourea derivative that is substantially free of or contains no histidine. For example, the total amount of the histidine thiourea derivative in the personal care composition may be about 2 wt.% or less, about 1 wt.% or less, about 0.5 wt.% or less, about 0.1 wt.% or less, or about 0.05 wt.% or less, based on the total weight of the personal care composition. In some embodiments, the personal care composition has about 0 or 0 wt.% of the histidine thiourea derivative.

[0083] Depending on the specific combination of other ingredients, the form of the personal care composition, and / or the purpose of the composition (e.g., emulsion, cream, spray, body wash, serum, etc.), suitable components, such as those listed below, may be included or excluded in the formulation of a personal care composition. For example, when the personal care composition is in the form of an emulsion or a two-phase composition, the personal care composition may contain a hydrophilic phase and a hydrophobic phase. In some embodiments, the personal care composition is in the form of a skin care cream, skin care emulsion, skin care lipid, body lotion, or serum.

[0084] Personal care compositions may be in the form of skin care compositions and typically contain one or more vitamin E and one or more B vitamins. The amount of vitamin E present in a personal care composition may be from about 0.1 to about 9 wt.%, based on the total weight of the personal care composition. In some cases, the total amount of the one or more vitamin E (vitamin E compound) may be from about 0.1 to about 7 wt.%, from about 0.1 to about 5 wt.%, from about 0.1 to about 4 wt.%, from about 0.1 to about 3 wt.%, from about 0.1 to about 2 wt.%, from about 0.1 to about 1 wt.%; from about 0.5 to about 9 wt.%, from about 0.5 to about 7 wt.%, from about 0.5 to about 5 wt.%, from about 0.5 to about 4 wt.%, from about 0.5 to about 3 wt.%, from about 0.5 to about 2 wt.%, from about 0.5 to about 1 wt.%; from about 1 to about 9 wt.%, from about 1 to about 7 wt.%, from about 1 to about 5 wt.%, from about 1 to about 4 wt.%, from about 1 to about 3 wt.%, from about 1 to about 2 wt.%; from about 1.5 to about 9 wt.%, from about 1.5 to about 7 wt.%, from about 1.5 to about 5 wt.%, from about 1.5 to about 4 wt.%, from about 1.5 to about 3 wt.%; from about 2 to about 9 wt.%. wt.%, about 2 to about 7 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%; about 3 to about 9 wt.%, about 3 to about 7 wt.%, about 3 to about 5 wt.%; about 5 to about 9 wt.%, about 5 to about 7 wt.%; about 7 to about 9 wt.%, or any range or subrange thereof, based on the total weight of the personal care composition.

[0085] As used herein, “vitamin E” refers to a family of compounds containing four tocopherol isomers and four tocotrienol isomers, unless otherwise stated. All eight isomers of vitamin E have a 6-chromanol ring structure and side chains. The four tocopherols contain fully saturated side chains and include α-tocopherol, γ-tocopherol, β-tocopherol, and δ-tocopherol. The four tocotrienols contain unsaturated side chains and include α-tocotrienol, γ-tocotrienol, β-tocotrienol, and δ-tocotrienol. The term “vitamin E” as used herein may refer to any one or more of the eight isomer compounds, unless otherwise stated. For example, vitamin E as used herein may be or include one or more of the following: α-tocopherol, γ-tocopherol, β-tocopherol, δ-tocopherol, α-tocotrienol, γ-tocotrienol, β-tocotrienol, δ-tocotrienol, or any combination thereof. In at least one embodiment, vitamin E includes at least one of the four tocopherols. It should be understood that vitamin E can be or includes natural form vitamin E, synthetic form vitamin E, or combinations thereof. Any one or more isomers of vitamin E can be in the "d" form, the "l" form, or a combination thereof. In some embodiments, vitamin E is vitamin E acetate or vitamin E succinate. In some embodiments, vitamin E is vitamin E acetate. One or more vitamin E compounds can be selected from any vitamin E disclosed herein.

[0086] One or more vitamin E may include vitamin E acetate, vitamin E succinate, vitamin E acetate, or combinations of two or more thereof. For example, vitamin E may be selected from the group consisting of: α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, α-tocotrienol, β-tocotrienol, γ-tocotrienol, δ-tocotrienol, tocopherol acetate, tocopherol phosphate, natural extracts rich in vitamin E derivatives, and combinations thereof.

[0087] Personal care compositions typically also contain one or more B vitamins, for example, in amounts of 1 to about 10 wt.%, based on the total weight of the personal care composition. For example, a personal care composition may contain vitamin B (vitamin B compounds) in total amounts of about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%, about 2 to about 3 wt.%; about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 4 wt.%; about 4 to about 10 wt.%, about 4 to about 8 wt.%, about 4 to about 5 wt.%; about 5 to about 10 wt.%, about 5 to about 8 wt.%, about 5 to about 7 wt.%; about 6 to about 10 wt.%, about 6 to about 8 wt.%; ... wt.%, or any range or subrange thereof, based on the total weight of the personal care composition.

[0088] Vitamin B can be selected from vitamin B1 (thiamine), vitamin B3 (niacin or nicotinamide), vitamin B2 (riboflavin), vitamin B5 (pantothenic acid), vitamin B7 (biotin), vitamin B9 (folic acid or folic acid), and vitamin B6. 12 (Cobalamin), its derivatives, and combinations of two or more thereof. As used herein, vitamin B generally refers to vitamin B compounds and / or their derivatives. Preferably, one or more vitamin B compounds are selected from vitamin B3 compounds. The one or more vitamin B compounds may consist of vitamin B3 and / or its derivatives. Vitamin B3 may comprise:

[0089] Wherein R is -CONH2 (i.e., nicotinamide), -COOH (i.e., nicotinic acid), or -CH2OH (i.e., nicotinol); its derivatives and / or salts thereof. Vitamin B3 is selected from the group consisting of: nicotinic acid esters, non-vasodilatory esters of nicotinic acid, nicotinic acid amino acids, nicotinol esters of carboxylic acids (e.g., straight-chain or branched, cyclic or acyclic, saturated or unsaturated (including aromatic), and substituted or unsubstituted), nicotinic acid N-oxide and nicotinamide N-oxide, tocopheryl nicotinate, inositol hexanicotinate, and / or combinations thereof.

[0090] Examples of nicotinamide derivatives include, for example, nicotinic amino acids derived from the reaction of activated nicotinic acid compounds (e.g., nicotinic acid azide or nicotinyl chloride) with amino acids, and organic carboxylic acids (e.g., C1-C12-C4 ... 18Nicotinic acid esters. Specific examples of such derivatives include nicotinic acid and nicotinyl isohydroxamic acid, which have the following chemical structures: Niacin Nicotinyl isohydroxamic acid

[0091] Other derivatives of nicotinamide include nicotinic acid esters, such as nicotinic acid esters of carboxylic acids, salicylic acid, acetic acid, glycolic acid, palmitic acid, etc. Other examples of nicotinamide derivatives include 2-chloronicotinamide, 6-aminonicotinamide, 6-methylnicotinamide, n-methylnicotinamide, n,n-diethylnicotinamide, n-(hydroxymethyl)nicotinamide, quinolinic acid imide, nicotinamide, n-benzylnicotinamide, n-ethylnicotinamide, nifenazine, nicotinic acid, isonicotinic acid, methyl isonicotinic acid, thionicotinamide, niacinamide, 1-(3-pyridinemethyl)urea, 2-mercaptonicotinic acid, nicomolar, nipraziamine, and combinations thereof.

[0092] In some preferred embodiments, the personal care composition is formulated to have a weight ratio of α-tocopherol to nicotinamide of about 1:1 to about 1:14. In some embodiments, the weight ratio of α-tocopherol to nicotinamide in the personal care composition is about 1:1 to about 1:13, about 1:1 to about 1:12, about 1:1 to about 1:11, about 1:1 to about 1:9, about 1:1 to about 1:7, about 1:1 to about 1:6, about 1:1 to about 1:5, about 1:1 to about 1:4, about 1:1 to about 1:3; about 1:2 to about 1:11, about 1:2 to about 1:9, about 1:2 to about 1:7, about 1:2 to about 1:4, about 1:2 to about 1:3; about 1:3 to about 1:13, about 1:3 to about 1:12, about 1:3 to about 1:11, about 1:3 to about 1:14. 9. About 1:3 to about 1:7, about 1:3 to about 1:6, about 1:3 to about 1:5, about 1:3 to about 1:4, about 1:3; about 1:4 to about 1:13, about 1:4 to about 1:12, about 1:4 to about 1:11, about 1:4 to about 1:9, about 1:4 to about 1:7, about 1:4 to about 1:6; about 1:5 to about 1:13, about 1:5 to about 1:12, about 1:5 to about 1:11, about 1:5 to about 1:9, about 1:5 to about 1:7, about 1:5 to about 1:6; about 1:6 to about 1:13, about 1:6 to about 1:12, about 1:6 to about 1:11, about 1:6 to about 1:9, about 1:6 to about 1:7, or any range or subrange thereof.

[0093] Personal care compositions typically contain amaranth extract. The amount of amaranth extract present in a personal care composition can be from about 0.05 to about 5 wt.%, based on the total weight of the personal care composition. In some embodiments, the amount of amaranth extract present in the personal care composition may be from about 0.05 to about 5 wt.%, from about 0.05 to about 4 wt.%, from about 0.05 to about 3 wt.%, from about 0.05 to about 2 wt.%, from about 0.05 to about 1 wt.%, from about 0.05 to about 0.7 wt.%; from about 0.1 to about 5 wt.%, from about 0.1 to about 4 wt.%, from about 0.1 to about 3 wt.%, from about 0.1 to about 2 wt.%, from about 0.1 to about 1 wt.%, from about 0.1 to about 0.7 wt.%; from about 0.3 to about 5 wt.%, from about 0.3 to about 4 wt.%, from about 0.3 to about 3 wt.%, from about 0.1 to about 2 wt.%, from about 0.3 to about 1 wt.%, from about 0.3 to about 0.7 wt.%; from about 0.5 to about 5 wt.%, from about 0.5 to about 4 wt.%, from about 0.5 to about 3 wt.%, from about 0.5 to about 2 wt.%; wt.%, about 0.5 to about 1 wt.%, about 0.5 to about 0.7 wt.%; about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%, about 1 to about 1.5 wt.%; about 1.5 to about 5 wt.%, about 1.5 to about 4 wt.%, about 1.5 to about 3 wt.%, about 1.5 to about 2 wt.%; about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; about 3 to about 5 wt.%, about 3 to about 4 wt.%, or any range or subrange thereof, based on the total weight of the personal care composition.

[0094] Amaranth extracts can be obtained from the seeds of Amaranth plants, preferably including proteins and starches obtained from Amaranth seeds. Amaranth extracts may contain aqueous, alcoholic, or oil carriers. Starch from Amaranth seeds is likely the most abundant non-solvent component in Amaranth extracts. Without being limited to any particular theory, it is believed that the particle size and rapid degradation by amylases of starch from Amaranth seeds may contribute to the beneficial properties of personal care compositions.

[0095] Preferably, the proteins contained in the amaranth extract are primarily composed of soluble proteins, such as albumin and globulins. Without being limited by any particular theory, it is believed that the amino acid composition of amaranth seed proteins has higher levels of lysine and sulfur-containing amino acids compared to other cereal seeds, contributing to an amino acid profile in the amaranth extract that is close to and / or similar to that of animal proteins.

[0096] In some cases, amaranth extracts can be obtained by extracting seeds with a suitable solvent at a temperature between room temperature and the solvent's boiling point, optionally grinding or flattening the seeds, recovering the liquid phase, and then treating it appropriately to obtain an aqueous solution of the amaranth extract. This solution can then be stabilized and / or sterilized, or the solvent can be evaporated until a dry, solid, powdered amaranth extract is obtained. Suitable solvents are advantageously selected from water, C1-C4 aliphatic alcohols, acetone, or mixtures thereof in all proportions, particularly water / acetone or water / alcohol mixtures, in proportions of 0 to 100% acetone or alcohol. The weight ratio of amaranth seeds to solvent can advantageously be from about 1:5 to about 1:20.

[0097] Personal care compositions may contain fatty acids other than short-chain fatty acids (also referred to herein as non-short-chain fatty acids), such as polyunsaturated fatty acids, including, for example, ω-3 fatty acids, ω-6 fatty acids, and / or ω-9 fatty acids. For example, a personal care composition may contain one or more non-short-chain fatty acids selected from: linolenic acid, octadecanoic acid, eicosapentaenoic acid, eicosapentaenoic acid, docosapentaenoic acid, linolenic acid, calendulatic acid, eicosadienoic acid, arachidonic acid, adrenaline, arbutinic acid, docosapentaenoic acid, palmitic acid, palmitoleic acid, stearic acid, oleic acid, isoleic acid, linolenic acid, α-linolenic acid, arachidic acid, and combinations of two or more thereof. In at least one embodiment, the personal care composition contains one or more of the following: palmitic acid, palmitoleic acid, stearic acid, oleic acid, isoleic acid, linolenic acid, α-linolenic acid, or arachidic acid. For example, personal care compositions may contain palmitic acid, palmitoleic acid, stearic acid, oleic acid, isoleic acid, linolenic acid, alpha-linolenic acid, and arachidic acid.

[0098] Examples of omega-3 fatty acids that may be incorporated into personal care compositions include or consist of the following: linolenic acid, octadecanoic acid, eicosapentaenoic acid, eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid. Personal care compositions may contain omega-6 fatty acids selected from or consisting of the following: linolenic acid, calendulanic acid, eicosadienoic acid, arachidonic acid, docosadienoic acid, adrenaline, octoporic acid, docosahexaenoic acid, and / or docosapentaenoic acid. In some cases, personal care compositions may contain a combination of omega-3 fatty acids and / or omega-6 fatty acids.

[0099] In some embodiments, the personal care composition comprises oleic acid and linolenic acid. The personal care composition may be formulated to have a weight ratio of oleic acid to linolenic acid of about 1:1 to about 1:4. For example, the weight ratio of oleic acid to linolenic acid in the personal care composition may be about 1:1 to about 1:4, about 1:1 to about 1:3, about 1:1 to about 1:2; about 1:1.5 to about 1:4, about 1:1.5 to about 1:3, about 1:1.5 to about 1:2, or any range or subrange thereof.

[0100] The amaranth extract preferably contains one or more non-short-chain fatty acids, such as those described above. In some preferred embodiments, the amaranth extract comprises a variety of non-short-chain fatty acids (such as ω-3 fatty acids, ω-6 fatty acids, ω-9 fatty acids), wherein the total amount of oleic acid and linolenic acid is about 40 to about 90 wt.% of the total fatty acids in the amaranth extract (e.g., about 50 to about 90 wt.%, about 55 to about 90 wt.%, about 40 to about 85 wt.%, and / or about 40 to about 80 wt.%). In some embodiments, the amaranth extract may have one of the above-described weight ratios of oleic acid to linolenic acid.

[0101] Additionally or alternatively, the personal care composition may contain vitamin C, preferably in an effective amount. The amount of vitamin C present in the personal care composition may be from about 0.1 to about 8 wt.%, based on the total weight of the personal care composition. For example, the total amount of vitamin C (or vitamin C compound) in a personal care composition may be from about 0.05 to about 7 wt.%, from about 0.05 to about 6 wt.%, from about 0.05 to about 4 wt.%, from about 0.05 to about 3 wt.%, from about 0.05 to about 2 wt.%, from about 0.05 to about 1 wt.%; from about 0.1 to about 8 wt.%, from about 0.1 to about 6 wt.%, from about 0.1 to about 4 wt.%, from about 0.1 to about 3 wt.%, from about 0.1 to about 2 wt.%, from about 0.1 to about 1 wt.%; from about 0.3 to about 8 wt.%, from about 0.3 to about 6 wt.%, from about 0.3 to about 4 wt.%, from about 0.3 to about 3 wt.%, from about 0.3 to about 2 wt.%, from about 0.3 to about 1 wt.%; from about 0.5 to about 8 wt.%, from about 0.5 to about 6 wt.%, from about 0.5 to about 4 wt.%, from about 0.5 to about 3 wt.%; wt.%, about 0.5 to about 2 wt.%, about 0.5 to about 1 wt.%; about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%; about 5 to about 8 wt.%, about 5 to about 7 wt.%, or any range or subrange thereof, based on the total weight of the personal care composition.

[0102] The "vitamin C" used in this article can refer to ascorbic acid or its derivatives. Ascorbic acid exists in two enantiomers, usually denoted as "l" (representing "levorotatory") and "d" (representing "dextral"). The "l" isomer is the most commonly encountered isomer. Ascorbic acid is also called L(+)-ascorbic acid or l-ascorbic acid. Ascorbic acid derivatives may include, but are not limited to, L-ascorbic acid, calcium ascorbate, L-calcium ascorbate dihydrate, magnesium ascorbate, potassium ascorbate, magnesium L-ascorbate phosphate (also known as magnesium ascorbate phosphate or magnesium ascorbate phosphate salt), sesqui-magnesium L-ascorbate-2-phosphate hydrate, sodium (+)-L-ascorbate, dehydro-l-(+)-ascorbic acid dimer, sodium ascorbate phosphate (also known as sodium ascorbate phosphate salt, sodium L-ascorbate phosphate, 2-phospho-L-ascorbate trisodium salt, L-ascorbic acid phosphate, etc.). Ascorbic acid-2-phosphate trisodium salt or L-ascorbic acid-2-phosphate sodium salt), ascorbic acid-2-glucoside, ascorbic acid dipalmitate, ascorbic acid methylsilanol pectate, ascorbic acid stearate, ascorbic acid sulfate disodium salt, ascorbic acid-6-palmitate, ascorbic acid calcium phosphate, ascorbic acid acetate, ascorbic acid propionate, ascorbic acid stearate, ascorbic acid palmitate, ascorbic acid dipalmitate, ascorbic acid glucoside, ascorbic acid polypeptide, ethyl ascorbic acid ether, ascorbic acid ethylsilanol pectate, etc., or combinations thereof. For example, a personal care composition contains vitamin C selected from ascorbic acid glucoside, ascorbic acid-2-glucoside, ascorbic acid acetate, and combinations of two or more thereof. In some embodiments, the personal care composition contains or consists of ascorbic acid glucoside, ascorbic acid-2-glucoside, or combinations thereof.

[0103] Personal care compositions may comprise one or more vitamin C compounds, said vitamin C compounds comprising or selected from ascorbate glucoside, ascorbate-2-glucoside, ascorbate acetate, tetrahexyldecyl ascorbate, and / or combinations of two or more thereof. The one or more vitamin C compounds may be selected from the group consisting of ascorbate glucoside, ascorbate-2-glucoside, ascorbate acetate, tetrahexyldecyl ascorbate, and combinations of two or more thereof. In some embodiments, the vitamin C present in the personal care composition comprises tetrahexyldecyl ascorbate. The amount of tetrahexyldecyl ascorbate may be from about 0.05 to about 1 wt.%, based on the total weight of the personal care composition. For example, the amount of tetrahexyldecyl ascorbate present in the personal care composition may be from about 0.05 to about 1 wt.%, from about 0.1 to about 1 wt.%, from about 0.2 to about 1 wt.%, from about 0.4 to about 1 wt.%, from about 0.6 to about 1 wt.%; from about 0.05 to about 0.8 wt.%, from about 0.1 to about 0.8 wt.%, from about 0.2 to about 0.8 wt.%, from about 0.4 to about 0.8 wt.%; from about 0.05 to about 0.6 wt.%, from about 0.1 to about 0.6 wt.%, from about 0.2 to about 0.6 wt.%; from about 0.05 to about 0.4 wt.%, from about 0.1 to about 0.4 wt.%, or any range or subrange thereof, based on the total weight of the personal care composition.

[0104] Additionally or alternatively, the personal care product may contain one or more short-chain fatty acids and / or their salts. The amount of one or more short-chain fatty acids and / or their salts present in the personal care composition may be from about 0.05 to about 7 wt.%, based on the total weight of the personal care composition. For example, the total amount of short-chain fatty acids and / or their salts in a personal care composition may be about 0.05 to about 5 wt.%, about 0.05 to about 4 wt.%, about 0.05 to about 3 wt.%, about 0.05 to about 2 wt.%, about 0.05 to about 1 wt.%, about 0.05 to about 0.7 wt.%; about 0.1 to about 5 wt.%, about 0.1 to about 4 wt.%, about 0.1 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.1 to about 1 wt.%, about 0.1 to about 0.7 wt.%; about 0.3 to about 5 wt.%, about 0.3 to about 4 wt.%, about 0.3 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.3 to about 1 wt.%, about 0.3 to about 0.7 wt.%; about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%. wt.%, about 0.5 to about 1 wt.%, about 0.5 to about 0.7 wt.%; about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%, about 1 to about 1.5 wt.%; about 1.5 to about 5 wt.%, about 1.5 to about 4 wt.%, about 1.5 to about 3 wt.%, about 1.5 to about 2 wt.%; about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; about 3 to about 7 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; about 5 to about 7 wt.%, about 5 to about 6 wt.%, or any range or subrange thereof, based on the total weight of the personal care composition.

[0105] Short-chain fatty acids can contain six or fewer carbon atoms. The short-chain fatty acids disclosed herein can, in some cases, be in salt form. Short-chain acids do not only refer to those with the formula C... n H 2n+1 Hydrocarbon acids of COOH (where n is 0 to 6), and specifically short-chain acids substituted with oxygen-containing groups such as alcohols or oxygen groups. Short-chain fatty acids may be selected from valeric acid, CH3CH2CH2CH2COOH, isovaleric acid, 3-methylbutyric acid, (CH3)2CHCH2COOH, 2-methylpropionic acid, (CH3)2CHCOOH, butyric acid, CH3CH2CH2COOH, CH3CH2COOH, acetic acid, CH3COOH, formic acid, HCOOH, acetic acid, succinic acid, formic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, isovaleric acid, lactic acid, pyruvic acid, their derivatives, their salts, and combinations of two or more thereof.

[0106] Preferably, the personal care composition comprises or is composed of lactic acid, pyruvate, acetic acid, mandelic acid, its derivatives, its salts, and / or combinations of two or more thereof. In some embodiments, the personal care composition may contain one or more short-chain fatty acids selected from lactic acid, acetic acid, pyruvate, its derivatives, its salts, or combinations of two or more thereof. In some embodiments, the personal care composition comprises pyruvate in salt form, such as sodium pyruvate.

[0107] Personal care compositions may have a weight ratio of lactic acid and / or its salts to pyruvate and / or its salts of about 6:1 to about 2:1. In some cases, the weight ratio of lactic acid and / or its salts to pyruvate and / or its salts of about 6:1 to about 2:1, about 5.75:1 to about 2.25:1, about 5.5:1 to about 2.5:1; about 5.25:1 to about 2.75:1, about 5:1 to about 3:1, about 4.75:1 to about 3.25:1, about 4.5:1 to about 3.5:1, or about 4.25:1 to about 3.75:1, including any range and subrange therein. In one embodiment, the weight ratio of lactic acid to pyruvate is about 4:1.

[0108] Additionally or alternatively, the personal care composition may be formulated to have a specific weight ratio of lactic acid and / or its salts to acetic acid and / or its salts. For example, the personal care composition may have a weight ratio of lactic acid and / or its salts to acetic acid and / or its salts of about 6:1 to about 2:1. In some cases, the weight ratio of lactic acid and / or its salts to pyruvate and / or its salts is about 6:1 to about 2:1, about 5.75:1 to about 2.25:1, about 5.5:1 to about 2.5:1; about 5.25:1 to about 2.75:1, about 5:1 to about 3:1, about 4.75:1 to about 3.25:1, about 4.5:1 to about 3.5:1, or about 4.25:1 to about 3.75:1, including any range and subrange therein. In one embodiment, the weight ratio of lactic acid to acetic acid is about 4:1.

[0109] In some embodiments, the personal care composition may contain one or more short-chain fatty acids discussed below.

[0110] Examples of short-chain acids containing one carbon atom include formic acid, methanoic acid, and HCOOH. Examples of short-chain acids containing two carbon atom include acetic acid, acetic acid, CH3COOH, oxalic acid, oxalic acid, HOOCCOOH, oxoethanoic acid, glyoxylic acid, formic acid, OHCCOOH, 2-hydroxyacetic acid, glycolic acid, dicarbonic acid, glycolic acid, and HOCH2COOH.

[0111] Examples of short-chain acids containing three carbon atoms include propionic acid, ethanecarboxylic acid, CH3CH2COOH, propionic-2-enoic acid, acrylic acid, acroleic acid, ethylene carboxylic acid, propene acid, ethyleneformic acid, CH2=CH-COOH, 2-propynic acid, propiolic acid, ethynic acid, propargylic acid, CH=C-COOH, propanedioic acid, malonic acid, methanedicarboxylic acid, HOOC–CH2–COOH, 2-hydroxymalonic acid, tartronic acid, hydroxymalonic acid, HOOC–CHOH–COOH, oxopropanedioic acid, mesoxalic acid, ketomalonic acid, HOOC–CO–COOH, 2,2-dihydroxymalonic acid, dihydroxymalonic acid, and mesoxalic acid monohydrate. acid monohydrate), HOOC–C(OH)2–COOH, 2-oxopropionic acid, pyruvic acid, α-ketopropionic acid, acetylated carboxylic acid, pyroracemic acid, CH3–CO–COOH, 2-hydroxypropionic acid, lactic acid, milk acid, CH3–CHOH–COOH, 3-hydroxypropionic acid, hydroxypropionic acid, CH2OH–CH2–COOH, 2,3-dihydroxypropionic acid, glyceric acid, CH2OH–CHOH–COOH, 2-oxiranecarboxylic acid, and glycidic acid.

[0112] Examples of short-chain acids containing four carbon atoms include butanoic acid, butyric acid, propanecarboxylic acid, CH3(CH2)2COOH, 2-methylpropionic acid, isobutyric acid, isobutyric acid, (CH3)2CHCOOH, 2-oxobutyric acid, α-ketobutyric acid, CH3-CH2-CO-COOH, 3-oxobutyric acid, acetoacetic acid, CH3CO–CH2–COOH, 4-oxobutyric acid, succinic acid semialdehyde, HC(O)–CH2–CH2–COOH, (E)-butenedioic acid, fumaric acid, trans-1,2-ethylenedicarboxylic acid, 2-butenedioic acid, trans-butenedioic acid, bema-maleic acid, litmus acid, donitic acid, and lichenic acid. (acid), HOOC-CH=CH-COOH, (Z)-butenic acid, maleic acid, cis-butenic acid, maleic acid, toxic acid, HOOC–CH=CH–COOH, oxosuccinic acid, oxaloacetic acid, oxosuccinic acid, HOOC–CH2–CO–COOH, hydroxybutanedioic acid, malic acid, hydroxybutanedioic acid, HOOC–CH2–CHOH–COOH, 2,3-dihydroxybutanedioic acid, tartaric acid, 2,3-dihydroxysuccinic acid, threaric acid, racemic acid, uvic acid, paratartaric acid (acid), HOOC(CHOH)2COOH, (E)-but-2-enoic acid, crotonic acid, trans-2-butenoic acid, β-methylacrylic acid, 3-methylacrylic acid, (E)-2-butenoic acid and CH3–CH=CH–COOH.

[0113] Examples of short-chain acids containing five carbon atoms include pentanoic acid, valeric acid, valerianic acid, butane-1-carboxylic acid, CH3(CH2)3COOH, 3-methylbutyric acid, isovaleric acid, (CH3)2CH-CH2-COOH, glutaric acid, glutaric acid, propane-1,3-dicarboxylic acid, 1,3-propanedicarboxylic acid, n-pyrotartaric acid, HOOC–(CH2)3–COOH, 2-oxopentanedioic acid, alpha-ketoglutaric acid, 2-ketoglutaric acid, α-ketoglutaric acid, 2-oxoglutaric acid, oxoglutaric acid, and HOOC–(CH2)2–CO–COOH.

[0114] Personal care compositions may contain one or more polysaccharides. In some cases, personal care compositions contain about 0.05 wt.% to about 10 wt.% of polysaccharides, based on the total weight of the personal care composition. For example, the total amount of polysaccharides present in the personal care composition may be about 0.05 to about 8 wt.%, about 0.05 to about 6 wt.%, about 0.05 to about 5 wt.%, about 0.05 to about 4 wt.%, about 0.05 to about 3 wt.%, about 0.05 to about 2 wt.%, about 0.05 to about 1 wt.%; about 0.1 to about 10 wt.%, about 0.1 to about 8 wt.%, about 0.1 to about 6 wt.%, about 0.1 to about 5 wt.%, about 0.1 to about 4 wt.%, about 0.1 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.1 to about 1 wt.%; about 0.5 to about 10 wt.%, about 0.5 to about 8 wt.%, about 0.5 to about 6 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%, about 0.5 to about 1 wt.% wt.%; about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%; about 4 to about 10 wt.%, about 4 to about 8 wt.%, about 4 to about 6 wt.%; about 6 to about 10 wt.%, about 6 to about 8 wt.%, or about 8 to about 10 wt.%, including ranges and subranges therein, based on the total weight of the personal care composition.

[0115] Examples of polysaccharides include, but are not limited to, cellulose, carboxymethyl hydroxyethyl cellulose, cellulose acetate propionate, hydroxyethyl cellulose, hydroxyethyl ethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, methyl hydroxyethyl cellulose, microcrystalline cellulose, sodium cellulose sulfate, gum arabic, agar, alginate, alginic acid, ammonium alginate, amylopectin, calcium alginate, calcium carrageenan, carnitine, carrageenan, dextrin, gelatin, gellan gum, guar gum, guar hydroxypropyltrimethylammonium chloride, lithium montmorillonite, hyaluronic acid, hydrated silica, hydroxypropyl chitosan, hydroxypropyl guar gum, ark pine gum, kelp gum, locust bean gum, natto gum, potassium alginate, potassium carrageenan, propylene glycol alginate, stearin gum, sodium carboxymethyl dextran, carrageenan, tragacanth gum, xanthan gum, biosaccharide gum, inulin, and combinations of two or more thereof. The polysaccharide may comprise or consist of polysaccharides selected from the group consisting of: inulin, carrageenan, galactooligosaccharides, fructooligosaccharides, α-glucan, β-glucan, and / or combinations thereof. In some embodiments, the polysaccharide comprises fructan, inulin, carrageenan, or a combination of two or more thereof. In at least one embodiment, the personal care composition comprises inulin.

[0116] Personal care compositions may contain fatty alcohols. The amount of fatty alcohols in a personal care composition may vary, but in some cases is from about 0.01 to about 12 wt.%, based on the total weight of the personal care composition. For example, the amount of fatty alcohol present in the personal care composition may be from about 0.01 to about 12 wt.%, from about 0.01 to about 10 wt.%, from about 0.01 to about 8 wt.%, from about 0.01 to about 6 wt.%, from about 0.01 to about 5 wt.%, from about 0.01 to about 4 wt.%, from about 0.01 to about 3 wt.%, from about 0.01 to about 2 wt.%, from about 0.01 to about 1 wt.%; from about 0.1 to about 12 wt.%, from about 0.1 to about 10 wt.%, from about 0.1 to about 8 wt.%, from about 0.1 to about 6 wt.%, from about 0.1 to about 5 wt.%, from about 0.1 to about 4 wt.%, from about 0.1 to about 3 wt.%, from about 0.1 to about 2 wt.%, from about 0.1 to about 1 wt.%; from about 0.5 to about 12 wt.%, from about 0.5 to about 10 wt.%, from about 0.5 to about 8 wt.%, from about 0.5 to about 6 wt.%; wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%, about 0.5 to about 1 wt.%; about 1 to about 12 wt.%, about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; about 2 to about 12 wt.%, about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%; about 4 to about 12 wt.%, about 4 to about 10 wt.%, about 4 to about 8 wt.%, about 4 to about 6 wt.%, including ranges and subranges therein, based on the total weight of the personal care composition.

[0117] The fatty alcohol may comprise or be selected from the group consisting of: decanol, undecanool, dodecanool, myristol, lauryl alcohol, cetyl alcohol, stearyl alcohol, cetearyl alcohol (cetyl alcohol and stearyl alcohol), isostearyl alcohol, isocetyl alcohol, betaine alcohol, linalool, oleyl alcohol, cis-4-tert-butylcyclohexanol, isotrigine alcohol, beeswax alcohol, and / or combinations of two or more thereof. In at least one embodiment, the fatty alcohol comprises or consists of 2-butyloctyl alcohol.

[0118] Other notable examples of fatty alcohols include certain saturated or unsaturated fatty alcohols. Saturated liquid fatty alcohols may be branched and optionally contain at least one aromatic or non-aromatic ring in their structure. However, in some cases, fatty alcohols are acyclic. Non-limiting examples of liquid saturated fatty alcohols include octyldodecanool, isostearyl alcohol, and 2-hexyldecyl alcohol.

[0119] Exemplary unsaturated liquid fatty alcohols typically contain at least one double or triple bond in their structure. For example, unsaturated fatty alcohols may contain several double bonds (e.g., 2 or 3 double bonds), which may be conjugated or non-conjugated. Unsaturated fatty alcohols may be straight-chain or branched, and may be acyclic or contain at least one aromatic or non-aromatic ring in their structure. Liquid unsaturated fatty alcohols may contain or be selected from oleyl alcohol, linoleyl alcohol, linolenyl alcohol, and undecenol.

[0120] The fatty alcohol can be an alkoxylated fatty alcohol, for example, having about 1 to about 100 moles of alkylene oxide per mole of alkoxylated fatty alcohol. Examples of alkoxylated fatty alcohols include stearyl alcohol polyethers (e.g., stearyl alcohol polyether-2, stearyl alcohol polyether-20, and stearyl alcohol polyether-21), laureth (e.g., laureth-4 and laureth-12), cetyl alcohol polyethers (e.g., cetyl alcohol polyether-10 and cetyl alcohol polyether-20), and ceteareth (e.g., ceteareth-2, ceteareth-10, and ceteareth-20). In at least one case, one or more alkoxylated fatty alcohols comprise stearyl alcohol polyether-20. In some cases, one or more alkoxylated fatty alcohols may exclusively be stearyl alcohol polyether-20.

[0121] Personal care compositions may contain fatty alcohol derivatives, such as methyl stearyl ether; 2-ethylhexyl dodecyl ether; stearyl acetate; cetyl propionate; cetyl polyether series compounds, such as cetyl polyether-1 to cetyl polyether-45, which are ethylene glycol ethers of cetyl alcohol, wherein the numbers indicate the amount of ethylene glycol moiety present; stearyl polyether series compounds, such as stearyl polyether-1 to 10, which are ethylene glycol ethers of stearyl alcohol, wherein the numbers indicate the amount of ethylene glycol moiety present; cetyl stearyl polyether-1 to cetyl stearyl polyether-10, which are ethylene glycol ethers of cetyl stearyl alcohol, i.e., mixtures of fatty alcohols mainly containing cetyl alcohol and stearyl alcohol, wherein the numbers indicate the amount of ethylene glycol moiety present; the C1-C of the aforementioned cetyl polyether, stearyl polyether and cetyl stearyl polyether compounds. 30Alkyl ethers; polyoxyethylene ethers of branched alcohols, such as octyl dodecyl alcohol ether, dodecyl pentadecyl alcohol ether, hexyl decyl alcohol ether and isostearyl alcohol ether; polyoxyethylene ethers of behenol; PPG ethers, such as PPG-9-stearyl alcohol polyether-3, PPG-11 steararyl alcohol ether, PPG-8-cetyl alcohol polyether-1 and PPG-10 cetyl alcohol ether; and combinations of two or more thereof.

[0122] In some embodiments, the personal care composition comprises one or more hyaluronic acids and / or their salts. Hyaluronic acid and / or its salts (e.g., sodium hyaluronate) may be present in an amount of about 0.05 to about 5 wt.% based on the total weight of the personal care composition. For example, the content of hyaluronic acid and / or its salts in a personal care composition may be from about 0.05 to about 5 wt.%, from about 0.05 to about 4 wt.%, from about 0.05 to about 3 wt.%, from about 0.05 to about 2 wt.%, from about 0.05 to about 1 wt.%, from about 0.05 to about 0.7 wt.%; from about 0.1 to about 5 wt.%, from about 0.1 to about 4 wt.%, from about 0.1 to about 3 wt.%, from about 0.1 to about 2 wt.%, from about 0.1 to about 1 wt.%, from about 0.1 to about 0.7 wt.%; from about 0.3 to about 5 wt.%, from about 0.3 to about 4 wt.%, from about 0.3 to about 3 wt.%, from about 0.1 to about 2 wt.%, from about 0.3 to about 1 wt.%, from about 0.3 to about 0.7 wt.%; from about 0.5 to about 5 wt.%, from about 0.5 to about 4 wt.%, from about 0.5 to about 3 wt.%, from about 0.5 to about 2 wt.%; wt.%, about 0.5 to about 1 wt.%, about 0.5 to about 0.7 wt.%; about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%, about 1 to about 1.5 wt.%; about 1.5 to about 5 wt.%, about 1.5 to about 4 wt.%, about 1.5 to about 3 wt.%, about 1.5 to about 2 wt.%; about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%, or any range or subrange thereof, based on the total weight of the personal care composition.

[0123] One or more hyaluronic acids may be in the form of salts, such as sodium hyaluronate. The average molecular weight of hyaluronic acid and / or its salts may be from about 1 to about 4 Mda. For example, the average molecular weight of hyaluronic acid and / or its salts can be about 1 to about 4 Mda, about 1 to about 3.5 Mda, about 1 to about 3 Mda, about 1 to about 2.75 Mda, about 1 to about 2.5 Mda, about 1 to about 2.25 Mda, about 1 to about 2 Mda; about 1.5 to about 4 Mda, about 1.5 to about 3.5 Mda, about 1.5 to about 3 Mda, about 1.5 to about 2.75 Mda, about 1.5 to about 2.5 Mda, about 1.5 to about 2.25 Mda, about 1.5 to about 2 Mda; about 1.75 to about 4 Mda, about 1.75 to about 3.5 Mda, about 1.75 to about 3 Mda, about 1.75 to about 2.75 Mda, about 1.75 to about 2.5 Mda, about 1.75 to about 2.25 Mda, about 1.75 to about 2 Mda; about 2 to about 4 Mda, about 2 to about 3.5 Mda, about 2 to about 3 Mda, about 2 to about 3 Mda, about 2 to about 3 Mda, about 1 to about 2.75 Mda, about 1.75 to about 2.5 Mda, about 1.75 to about 2.25 Mda, about 1.75 to about 2 Mda; about 2 to about 4 Mda, about 2 to about 3.5 Mda, about 2 to about 3 Mda, about 2 to about 3 Mda, about 1 to about 2.75 Mda, about 1.75 to about 2.5 Mda, about 1.75 to about 2 Mda, about 1.75 to about 2 Mda; about 2 to about 4 Mda Mda, about 2 to about 2.75 Mda, about 2 to about 2.5 Mda, about 2 to about 2.25 Mda; about 2.25 to about 4 Mda, about 2.25 to about 3.5 Mda, about 2.25 to about 3 Mda, about 2.25 to about 2.75 Mda, about 2.25 to about 2.5 Mda; about 2.5 to about 4 Mda, about 2.5 to about 3.5 Mda, about 2.5 to about 3 Mda, about 2.5 to about 2.75 Mda; about 2.75 to about 4 Mda, about 2.75 to about 3.5 Mda, about 2.75 to about 3 Mda; about 3 to about 4 Mda, about 3 to about 3.5 Mda, about 3.5 to about 4 Mda, or any range or subrange thereof.

[0124] Personal care compositions may contain one or more polyols, the amount of which may vary depending on the form of the personal care composition and / or other components therein. The amount of polyols in a personal care composition may be from about 1% to about 30% based on the total weight of the personal care composition. For example, the amount of polyol present in the personal care composition may be from about 1 to about 30 wt.%, from about 1 to about 25 wt.%, from about 1 to about 20 wt.%, from about 1 to about 15 wt.%, from about 1 to about 10 wt.%, from about 1 to about 8 wt.%, from about 1 to about 6 wt.%, from about 1 to about 4 wt.%; from about 5 to about 30 wt.%, from about 5 to about 25 wt.%, from about 5 to about 22 wt.%, from about 5 to about 20 wt.%, from about 5 to about 18 wt.%, from about 5 to about 16 wt.%; from about 8 to about 30 wt.%, from about 8 to about 25 wt.%, from about 10 to about 22 wt.%, from about 10 to about 20 wt.%, from about 10 to about 18 wt.%, from about 10 to about 16 wt.%; from about 10 to about 30 wt.%, from about 10 to about 25 wt.%, from about 10 to about 22 wt.%, from about 10 to about 20 wt.%, from about 10 to about 18 wt.%, from about 10 to about 16 wt.%; wt.%; about 12 to about 30 wt.%, about 12 to about 25 wt.%, about 12 to about 22 wt.%, about 12 to about 20 wt.%, about 12 to about 18 wt.%, about 12 to about 16 wt.%; about 14 to about 30 wt.%, about 14 to about 25 wt.%, about 14 to about 22 wt.%, about 14 to about 20 wt.%, about 14 to about 18 wt.%, about 14 to about 16 wt.%, including its range and subranges, based on the total weight of the personal care composition.

[0125] Polyols can be selected from diols or compounds having multiple hydroxyl groups. Within the meaning of this disclosure, the term "polyol" should be understood to refer to an organic molecule containing at least two free hydroxyl groups. The polyol in a personal care composition can be a diol or a compound having multiple hydroxyl groups. In some cases, one or more polyols are selected from C2-C6. 32 The group consisting of polyols. The one or more polyols may have 2 to 32 carbon atoms, 3 to 16 carbon atoms, or 3 to 12 carbon atoms.

[0126] In some cases, polyols that may be included in personal care compositions include ethylene glycol, propylene glycol, octyl ethylene glycol, butylene glycol, hexanediol, glycerin, diglycerol, diethylene glycol, and dipropylene glycol, and mixtures thereof. In some cases, the polyol is octyl ethylene glycol. Other non-limiting examples of polyols that may optionally be included in personal care compositions include and / or may be selected from alkanediols such as glycerin, 1,2,6-hexanetriol, trimethylolpropane, ethylene glycol, propylene glycol, butylene glycol, pentanediol, hexanediol, diethylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol, 2-buten-1,4-diol, 2-ethyl-1,3-hexanediol, 2-methyl-2,4-pentanediol, octyl ethylene glycol, 1,2-hexanediol, 1,2-pentanediol, and 4-methyl-1,2-pentanediol; glycol ethers (glycol) Ethers, such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monomethyl ether acetate, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol mono-n-propyl ether, ethylene glycol monoisopropyl ether, diethylene glycol monoisopropyl ether, ethylene glycol mono-n-butyl ether, ethylene glycol mono-tert-butyl ether, diethylene glycol mono-tert-butyl ether, 1-methyl-1-methoxybutanol, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol mono-tert-butyl ether, propylene glycol mono-n-propyl ether, propylene glycol monoisopropyl ether, dipropylene glycol monomethyl ether, dipropylene glycol monoethyl ether, dipropylene glycol mono-n-propyl ether, dipropylene glycol monoisopropyl ether, sorbitol, anhydrosorbitol, triacetin, and combinations of two or more thereof.

[0127] Personal care compositions may contain one or more polyols as humectants. Examples of humectants that may be incorporated in some embodiments include triethylene glycol, tripropylene glycol, octyl ethylene glycol, propylene glycol, glycerin, polyethylene glycol, polypropylene glycol, glycerin, sorbitol, hexanediol, butylene glycol, hyaluronic acid, 1,2-hexanediol, glycoisomers, and combinations of two or more thereof. In some cases, the one or more humectants comprise at least one of glycerin, propylene glycol, or polyethylene glycol, and optionally one or more additional humectants.

[0128] Additionally or alternatively, the personal care composition may contain one or more skin soothing agents, such as bisabolol, aloe vera extract, allantoin, licorice extract, glycyrrhizin, or combinations thereof. In some preferred embodiments, the personal care composition contains two or more skin soothing agents. For example, the personal care composition may contain two, three, four, five, six, seven, or any range thereof of skin soothing agents. In at least one embodiment, the personal care composition contains bisabolol.

[0129] In some implementations, the soothing agent may be selected from natural extracts, including: bisabolol, centella asiatica extract, polygonum cuspidatum root extract, scutellaria baicalensis root extract, camellia sinensis leaf extract, licorice root extract, chamomile recutita flower extract, rosemary leaf extract, tea leaf extract, poria cocos extract, phragmites karka extract, lidocaine, chia seed extract, Rosa centifolia flower extract, aloe vera, allantoin, D-panthenol, turmeric, avocado oil, and lichen extract, or a combination of two or more of these.

[0130] The personal care composition may contain about 0.05 to about 5 wt.% of a soothing agent, based on the total weight of the personal care composition. In some embodiments, the total amount of the soothing agent in the personal care composition is about 0.05 to about 5 wt.%, about 0.05 to about 4 wt.%, about 0.05 to about 3 wt.%, about 0.05 to about 2 wt.%, about 0.05 to about 1 wt.%, about 0.05 to about 0.7 wt.%; about 0.1 to about 5 wt.%, about 0.1 to about 4 wt.%, about 0.1 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.1 to about 1 wt.%, about 0.1 to about 0.7 wt.%; about 0.3 to about 5 wt.%, about 0.3 to about 4 wt.%, about 0.3 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.3 to about 1 wt.%, about 0.3 to about 0.7 wt.%; about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%. wt.%, about 0.5 to about 1 wt.%, about 0.5 to about 0.7 wt.%; about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%, about 1 to about 1.5 wt.%; about 1.5 to about 5 wt.%, about 1.5 to about 4 wt.%, about 1.5 to about 3 wt.%, about 1.5 to about 2 wt.%; about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; about 3 to about 5 wt.%, about 3 to about 4 wt.%, or any range or subrange thereof, based on the total weight of the personal care composition.

[0131] The personal care composition may contain one or more thickeners. The amount of thickener in the composition may be from about 1 to about 25 wt.%, based on the total weight of the personal care composition. In some cases, the total amount of one or more thickeners present in the personal care composition is about 2 to about 25 wt.%, about 3 to about 25 wt.%, about 4 to about 25 wt.%, about 5 to about 25 wt.%, about 7.5 to about 25 wt.%, about 10 to about 25 wt.%, about 15 to about 25 wt.%, about 20 to about 25 wt.%; about 1 to about 20 wt.%, about 2 to about 20 wt.%, about 3 to about 20 wt.%, about 4 to about 20 wt.%, about 5 to about 20 wt.%, about 7.5 to about 20 wt.%, about 10 to about 20 wt.%, about 15 to about 20 wt.%; about 1 to about 15 wt.%, about 2 to about 15 wt.%, about 3 to about 15 wt.%, about 4 to about 15 wt.%, about 5 to about 15 wt.%, about 7.5 to about 15 wt.%, about 10 to about 15 wt.%; about 1 to about 10 wt.%, about 2 to about 10 wt.%, about 3 to about 10 wt.%, about 4 to about 10 wt.%, about 5 to about 10 wt.%, about 7.5 to about 10 wt.%; about 1 to about 7.5 wt.%, about 2 to about 7.5 wt.%, about 3 to about 7.5 wt.%, about 4 to about 7.5 wt.%, about 5 to about 7.5 wt.%; about 1 to about 5 wt.%, about 2 to about 5 wt.%, about 3 to about 5 wt.%, about 4 to about 5 wt.%; about 1 to about 4 wt.%, about 2 to about 4 wt.%, about 3 to about 4 wt.%, including all ranges and subranges therein, based on the total weight of the personal care composition.

[0132] Thickeners may be selected from carboxylic acid polymers; cross-linked polyacrylate polymers; polyacrylamide polymers; gums; polysaccharides; and combinations of two or more thereof. Examples of polysaccharides include cellulose, carboxymethyl hydroxyethyl cellulose, cellulose acetate propionate carboxylate, hydroxyethyl cellulose, hydroxyethyl ethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, methyl hydroxyethyl cellulose, microcrystalline cellulose, sodium cellulose sulfate, and mixtures thereof.

[0133] Non-limiting examples of carboxylic acid polymers include cross-linked carboxylic acid polymers containing one or more monomers derived from acrylic acid, substituted acrylic acid, and salts and esters of such acrylic and substituted acrylic acids, such as carbomer. Non-limiting examples of these gelling gums include gum arabic, agar, alginate, alginic acid, ammonium alginate, amylopectin, calcium alginate, calcium carrageenan, carnitine, carrageenan, dextrin, gelatin, gellan gum, guar gum, guar hydroxypropyltrimethylammonium chloride, lithium montmorillonite, hyaluronic acid, hydrated silica, hydroxypropyl chitosan, hydroxypropyl guar gum, ark tarragon gum, kelp gum, locust bean gum, natto gum, potassium alginate, potassium carrageenan, propylene glycol alginate, stearin gum, sodium carboxymethyl dextran, sodium carrageenan, tragacanth gum, xanthan gum, and combinations of two or more thereof.

[0134] In some cases, personal care compositions may be formulated with thickening polymers such as polyvinyl alcohol, sodium polyacrylate, sodium polymethacrylate, glyceryl polyacrylate, carboxyvinyl polymers, polyacrylamide, polyvinylpyrrolidone, polyvinyl methyl ether, polyvinyl sulfone, maleic acid copolymers, polyethylene oxide, polydiallylamine, polyethyleneimine, water-soluble cellulose derivatives (e.g., carboxymethyl cellulose, methyl cellulose, methyl hydroxypropyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, sodium cellulose sulfate) and / or starch derivatives (e.g., oxidized starch, dialdehyde starch, dextrin, British gum, acetyl starch, phosphate starch, carboxymethyl starch, hydroxyethyl starch, hydroxypropyl starch). In some embodiments, the thickener is selected from hydroxypropyl methyl cellulose, polyethylene glycol (PEG), polyacrylic acid, crosslinked homopolymers of acrylic acid, and acrylic acid C. 10-30 Acrylates of alkyl ester crosslinked polymers.

[0135] Personal care compositions may contain one or more fatty compounds. In some cases, personal care compositions contain about 0.1 to about 20 wt.% of one or more fatty compounds, based on the total weight of the personal care composition.In some cases, the total amount of aliphatic compounds is about 0.1 to about 20 wt.%, about 0.1 to about 18 wt.%, about 0.1 to about 16 wt.%, about 0.1 to about 14 wt.%, about 0.1 to about 12 wt.%, about 0.1 to about 10 wt.%, about 0.1 to about 8 wt.%, about 0.1 to about 7 wt.%, about 0.1 to about 6 wt.%, about 0.1 to about 5 wt.%; about 0.5 to 20 wt.%, about 0.5 to about 18 wt.%, about 0.5 to about 16 wt.%, about 0.5 to about 14 wt.%, about 0.5 to about 12 wt.%, about 0.5 to about 10 wt.%, about 0.5 to about 8 wt.%, about 0.5 to about 7 wt.%, about 0.5 to about 5 wt.%; about 1 to about 20 wt.%, about 1 to about 18 wt.%, about 1 to about 16 wt.%; wt.%, about 1 to about 14 wt.%, about 1 to about 12 wt.%, about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 7 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%; about 2 to about 20 wt.%, about 2 to about 18 wt.%, about 2 to about 16 wt.%, about 2 to about 14 wt.%, about 2 to about 12 wt.%, about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 7 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%; about 3 to about 20 wt.%, about 3 to about 18 wt.%, about 3 to about 16 wt.%, about 3 to about 14 wt.%, about 3 to about 12 wt.%, about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 7 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%; about 4 to about 20 wt.%, about 4 to about 18 wt.%, about 4 to about 16 wt.%, about 4 to about 14 wt.%, about 4 to about 12 wt.%, about 4 to about 10 wt.%, about 4 to about 8 wt.%, about 4 to about 7 wt.%, about 4 to about 6 wt.%, about 4 to about 5 wt.%; about 5 wt.% to about 20 wt.%, about 5 wt.% to about 18 wt.%, about 5 wt.% to about 16 wt.%, about 5 wt.% to about 14 wt.%, about 5 wt.% to about 12 wt.%, about 5 wt.% to about 10 wt.%, or about 5 wt.% to about 8 wt.%, about 5 wt.% to about 7 wt.%, or about 5 wt.% to about 6 wt.%, including all ranges and subranges thereof, based on the total weight of the personal care composition.

[0136] The fatty compound, if present, may be selected from oils, waxes, fatty alcohols, fatty acids, fatty esters, fatty ethers, triglyceride compounds, and mixtures thereof. The fatty compound may include or be selected from one or more oils. The term "oil" refers to any fatty substance that is liquid at room temperature (24-25°C) and atmospheric pressure (760 mmHg). Oils may be hydrocarbon-based oils, such as saturated hydrocarbon oils, unsaturated hydrocarbon oils, lipids, triglycerides, natural oils, and / or synthetic oils. The one or more oils may be synthetic oils and / or plant-based oils. For example, oils may be synthetic oils, such as mineral oils and / or alkanes (paraffins). In some cases, light (low viscosity) highly branched hydrocarbon oils may also be suitable. In at least one embodiment, the personal care composition comprises an oil, such as isododecane, isodecane, decane, dodecane, or a combination of two or more thereof.

[0137] In some implementations, the oil is selected from plant-based or vegetable-based oils, such as coconut oil, soybean oil, canola oil, rapeseed oil, corn oil, cottonseed oil, olive oil, palm oil, peanut oil, safflower oil, sesame oil, sunflower oil, flaxseed oil, palm kernel oil, tung oil, jatropha oil, mustard seed oil, flaxseed oil, pennycress oil, castor oil, wheat germ oil, apricot kernel oil, pistachio oil, pine oil, avocado oil, hazelnut oil, grapeseed oil, colza oil, juniper oil, peach kernel oil, coffee bean oil, jojoba oil, and mixtures thereof.

[0138] Other skin and / or hair compatible oils include a range of liquid hydrocarbons, such as straight-chain and branched oils like liquid paraffin, squalene, squalane, mineral oil, and low-viscosity synthetic hydrocarbons like polyalphaolefins and polybutene. Other useful skin and / or compatible oils can be silicone-based, such as straight-chain and cyclic polydimethylsiloxanes, organofunctional silicone oils (alkyl and alkylaryl), and amino silicone oils.

[0139] In some cases, the fatty compound may include or be selected from one or more waxes. Non-limiting examples of such waxes include, for example, synthetic waxes, pure ceresin, paraffin wax, polyethylene wax, illipe butter, beeswax, carnauba wax, microcrystalline wax, lanolin, lanolin derivatives, candelilla wax, cocoa butter, cinnamon wax, spermaceti, bran wax, capok wax, sugarcane wax, lignite wax, whale wax, lauryl wax, acacia decurrents flower wax, plant waxes (such as sunflower seed wax, carnauba wax, candelilla wax, ouricury wax, or Japanese wax, or cork fiber wax, or sugarcane wax), or mixtures thereof. In some embodiments, the fatty compound is a fatty acid ester selected from, including, glycerol fatty acid esters, dehydrated sorbitol fatty acid esters, ethoxylated fatty acid esters, synthetic esters, and combinations of two or more thereof.

[0140] In some embodiments, the personal care composition may contain a surfactant. The surfactant may be any anionic, nonionic, amphoteric, or zwitterionic surfactant, or a combination thereof. The amount of surfactant in the composition may be from about 1 to about 25 wt.%, based on the total weight of the personal care composition. In some cases, the amount of surfactant present in the personal care composition is about 2 to about 25 wt.%, about 3 to about 25 wt.%, about 4 to about 25 wt.%, about 5 to about 25 wt.%, about 7.5 to about 25 wt.%, about 10 to about 25 wt.%, about 15 to about 25 wt.%, about 20 wt.% to about 25 wt.%; about 1 to about 20 wt.%, about 2 to about 20 wt.%, about 3 to about 20 wt.%, about 4 to about 20 wt.%, about 5 to about 20 wt.%, about 7.5 to about 20 wt.%, about 10 to about 20 wt.%, about 15 to about 20 wt.%; about 1 to about 15 wt.%, about 2 to about 15 wt.%, about 3 to about 15 wt.%, about 4 to about 15 wt.%, about 5 to about 15 wt.%, about 7.5 to about 15 wt.%, about 10 to about 15 wt.%; about 1 to about 10 wt.%, about 2 to about 10 wt.%, about 3 to about 10 wt.%, about 4 to about 10 wt.%, about 5 to about 10 wt.%, about 7.5 to about 10 wt.%; about 1 to about 7.5 wt.%, about 2 to about 7.5 wt.%, about 3 to about 7.5 wt.%, about 4 to about 7.5 wt.%, about 5 to about 7.5 wt.%; about 1 to about 5 wt.%, about 2 to about 5 wt.%, about 3 to about 5 wt.%, about 4 to about 5 wt.%; about 1 to about 4 wt.%, about 2 to about 4 wt.%, about 3 to about 4 wt.%, including all ranges and subranges thereof, based on the total weight of the personal care composition.

[0141] In at least one embodiment, multiple surfactants are used to achieve the desired product quality. The primary surfactant provides good foaming ability and cleaning effect, while the secondary surfactant increases mildness to prevent irritation or excessive dryness of the skin. To prevent component separation, emulsifiers, such as diethanolamine, may be added.

[0142] A variety of anionic surfactants can be used in personal care compositions, including, for example, long-chain alkyl (C6-C6) surfactants. 22 Substances such as long-chain alkyl sulfates, long-chain alkyl sulfonates, long-chain alkyl phosphates, long-chain alkyl ether sulfates, long-chain alkyl α-olefin sulfonates, long-chain alkyl taurines, long-chain alkyl hydroxyethyl sulfonates (SCI), long-chain alkyl glycerol ether sulfonates (AGES), sulfosuccinates, etc.

[0143] The composition may also contain amphoteric surfactants. These surfactants are typically characterized by a combination of high surfactant activity, foaming properties, and mildness. Amphoteric surfactants include, but are not limited to, derivatives of aliphatic secondary and tertiary amines, wherein the aliphatic groups can be linear or branched and one of the aliphatic substituents contains about 8 to about 18 carbon atoms, and one contains an anionic water-solubilizing group, such as a carboxyl group, sulfonic acid group, sulfate group, phosphate group, or phosphonic acid group. Examples of such compounds include sodium 3-dodecylaminopropionate, sodium 3-dodecylaminopropanesulfonate, N-alkyl taurine, and N-higher alkyl aspartic acids. Other examples of amphoteric surfactants include, but are not limited to, a range of betaines, including, for example, high-alkyl betaines such as cocodimethylcarboxymethyl betaine, lauryldimethylcarboxymethyl betaine, lauryldimethylα-carboxyethyl betaine, cetyldimethylcarboxymethyl betaine, lauryl bis(2-hydroxyethyl)carboxymethyl betaine, stearyl bis(2-hydroxypropyl)carboxymethyl betaine, oleyldimethylγ-carboxypropyl betaine, and lauryl bis(2-hydroxypropyl)α-carboxyethyl betaine; sulfonated betaines such as cocodimethylsulfonated propyl betaine and stearyl dimethylsulfonated propyl betaine; and amide betaines, amide sulfobetaines, etc. Betaines having long-chain alkyl groups, particularly cocodiyl groups, can be useful, as can those including amide groups such as cocamidopropyl and cocamidoethyl betaine. Amphoteric surfactants can be in the form of salts.

[0144] Personal care compositions may contain one or more nonionic surfactants. Examples of nonionic surfactants include polysorbate 20, which has C8-C4. 22 Alkyl long-chain alkyl glucosides; coconut fatty acid monoethanolamides, such as cocamide MEA; coconut fatty acid diethanolamides, fatty alcohol ethoxylates (alkyl polyethylene glycol); alkylphenol polyethylene glycol; alkyl thiol polyethylene glycol; fatty amine ethoxylates (alkylamino polyethylene glycol); fatty acid ethoxylates (acyl polyethylene glycol); polypropylene glycol ethoxylates (e.g., PLURONIC™ block copolymers available from BASF); fatty acid alkylolamides (fatty acid amide polyethylene glycol); N-alkyl-, N-alkoxy polyhydroxy fatty acid amides; sucrose esters; sorbitan esters; polyethylene glycol ethers; and combinations thereof.

[0145] Nonionic surfactants may be selected from secondary alcohol ethoxylates, polyoxyethylene stearyl ethers, polyoxyethylene ethers, and mixtures of two or more thereof. Personal care compositions may comprise blends of nonionic surfactants containing two or more fatty alcohol ethoxylates, each fatty alcohol ethoxylate having a polyethylene oxide chain length of at least 2. Preferred fatty alcohol ethoxylates typically have a C0.05... 12 To C 24 The chain length of the fatty alcohol, the degree of unsaturation of 0-2, and the chain length of the polyethylene oxide of 2 to 150 ethylene oxide units are all considered. For example, fatty alcohol ethoxylates can have the general formula: CH3--(CH2). x --CH2--O--(CH2--CH2--O--) y H-, where X = 10-20, Y = 2-100. In some cases, blends of fatty alcohol ethoxylates comprise at least one fatty alcohol ethoxylate having a long polyethylene oxide chain length and at least one fatty alcohol ethoxylate having a short polyethylene oxide chain length. Suitable long-chain fatty alcohol ethoxylates have a polyethylene oxide chain length greater than 20, preferably 21 to 150, more preferably 21 to 100.

[0146] Examples of long-chain fatty alcohol ethoxylates include stearyl alcohol polyether-100 (100 denotes the polyethylene oxide chain length) and stearyl alcohol polyether-21. Other long-chain fatty alcohol ethoxylates may be used, such as cetyl alcohol polyether-100, oleyl alcohol polyether-100, myreth-100, and beheneth-100. Examples of short-chain long fatty alcohol ethoxylates include those with a polyethylene oxide chain length of less than or equal to 20, preferably 2 to 20. For example, short-chain long fatty alcohol ethoxylates may be selected from stearyl alcohol polyether-2, stearyl alcohol polyether-10, cetyl alcohol polyether-20, stearyl alcohol polyether-20, myreth-10, oleyl alcohol polyether-20, and beheneth-10.

[0147] Nonionic surfactants may be selected from polyoxyethylene ethers, such as polyoxyethylene stearyl ether compounds. Polyoxyethylene ethers may comprise mixtures of high molecular weight saturated fatty alcohols (such as cetyl alcohol and stearyl alcohol) and ethylene oxide. Polyoxyethylene ethers may be selected from cetearyl alcohol polyether-2, cetearyl alcohol polyether-3, cetearyl alcohol polyether-4, cetearyl alcohol polyether-5, cetearyl alcohol polyether-6, cetearyl alcohol polyether-7, cetearyl alcohol polyether-8, cetearyl alcohol polyether-9, cetearyl alcohol polyether-10, cetearyl alcohol polyether-11, cetearyl alcohol polyether-12, and combinations of two or more thereof. Examples of polyoxyethylene stearyl ether compounds include stearyl alcohol polyether-2, stearyl alcohol polyether-4, stearyl alcohol polyether-6, stearyl alcohol polyether-7, stearyl alcohol polyether-21, stearyl alcohol polyether-10, stearyl alcohol polyether-11, stearyl alcohol polyether-13, stearyl alcohol polyether-15, stearyl alcohol polyether-20, or combinations of two or more thereof. The nonionic surfactant may be in the form of a salt. In one embodiment, the personal care composition comprises one or more nonionic surfactants, including PEG-40 hydrogenated castor oil.

[0148] Personal care compositions may contain one or more pH adjusters to increase or decrease the overall pH of the personal care composition. For example, one or more acids may be contained to decrease the pH of the personal care composition. Examples of suitable acids for decreasing the pH of a personal care composition include, but are not limited to, citric acid, acetic acid, etc. Personal care compositions may contain one or more bases, such as sodium hydroxide, potassium hydroxide, etc., to increase the pH of the personal care composition. Additional or alternative acids and bases suitable for adjusting the pH of personal care compositions are readily known to those skilled in the art.

[0149] The amount of pH adjuster in a personal care composition may be based on the desired pH of the final personal care composition and / or product. For example, the total amount of pH adjuster may be from about 0.05 to about 20 wt.%, based on the total weight of the personal care composition. In some cases, the total amount of pH adjuster may be from about 0.05 to about 15 wt.%, from about 0.1 to about 10 wt.%, or from about 0.12 to about 5 wt.%, including ranges and subranges therein, based on the total weight of the personal care composition.

[0150] In some embodiments, the personal care composition has a pH of about 3.5 to about 10.0. In other embodiments, the personal care composition has a pH of about 3.5 to about 8.0. In some embodiments, the personal care composition has a pH of about 3.5 to about 7.5. In other embodiments, the personal care composition has a pH of about 3.5 to about 7. In a further embodiment, the personal care composition has a pH of about 3.5 to about 6.5. Other embodiments provide personal care compositions having a pH of about 3.5 to about 6. Other embodiments provide personal care compositions having a pH of about 3.5 to about 5.5. Still other embodiments provide personal care compositions having a pH of about 3.5 to about 5. In some embodiments, the personal care composition has a pH of about 3.75 to about 4.5. In some embodiments, the personal care composition is a body wash having a pH of about 4 to about 6.

[0151] Additional ingredients may be present in personal care compositions. These include ingredients for thickening, preservation, emulsification, adding fragrance, adjusting pH, and color. Personal care compositions may contain any of the following additional ingredients in amounts from about 0.01 to about 5 wt.%. In some cases, the amount of additional ingredients present in the personal care composition is about 0.01 to about 4 wt.%, about 0.01 to about 3 wt.%, about 0.01 to about 2 wt.%, about 0.01 to about 1 wt.%, about 0.01 to about 0.5 wt.%, about 0.01 to about 0.1 wt.%; about 0.1 to about 5 wt.%, about 0.1 to about 4 wt.%, about 0.1 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.1 to about 1 wt.%, about 0.1 to about 0.5 wt.%, about 0.1 to about 0.1 wt.%; about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%, about 0.5 to about 1 wt.%; about 0.75 to about 5 wt.%, about 0.75 to about 4 wt.%, about 0.75 to about 3 wt.%, about 0.75 to about 2 wt.%. wt.%, about 0.75 to about 1 wt.%; about 1 to about 5 wt.%; about 1 to about 4 wt.%; about 1 to about 3 wt.%; about 1 to about 2 wt.%; about 2 to about 5 wt.%; about 2 to about 4 wt.%; about 2 to about 3 wt.%; about 3 to about 5 wt.%; about 3 to about 4 wt.%, including any range or subrange therein, based on the total weight of the personal care composition.

[0152] Personal care compositions may contain additional ingredients such as proteins (e.g., hydrolyzed vegetable protein, hydrolyzed wheat protein, hydrolyzed milk protein, hydrolyzed silk protein, and hydrolyzed collagen), emollients (e.g., esters, isopropyl myristate, decyl oleate, C12-15 alkyl benzoate), plant preparations (e.g., chamomile, aloe vera, rosemary), as well as preservatives, dyes, pH adjusters, and chelating agents. Other examples of vitamins that may be included in some personal care compositions include tocopherol, retinol, and ascorbic acid.

[0153] Non-limiting examples of fragrances and flavorings include odor compounds selected from the following: 7-acetyl-1,2,3,4,5,6,7,8-octahydro-1,1,6,7-tetramethylnaphthalene, α-ionone, β-ionone, γ-ionone, α-isomethylionone, methyl cypressone, methyl dihydrojasmone, methyl-1,6,10-trimethyl-2,5,9-cyclododecanetrien-1-yl ketone, 7-acetyl-1,1,3,4,4,6-hexamethyltetrahydronaphthalene, 4-acetyl-6-tert-butyl-1,1-dimethylindanone, hydroxyphenylbutanone, benzophenone, methyl-β-naphthyl ketone, 6-Acetyl-1,1,2,3,3,5-Hexamethylindane, 5-Acetyl-3-isopropyl-1,1,2,6-Tetramethylindane, 1-Dodecaldehyde, 4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde, 7-hydroxy-3,7-dimethyloctanal, 10-undecene-1-aldehyde, isohexenylcyclohexylcarboxaldehyde, formyltricyclodecane, condensation product of hydroxycitronellol and methyl anthranilate, condensation product of hydroxycitronellol and indole, condensation product of phenylacetaldehyde and indole, 2-methyl-3-(p-tert-butylphenyl)propanal, ethyl vanillin, hexamonal, hexylcinnamaldehyde, pentylcinnamaldehyde, 2-methyl-2-(isopropylphenyl)propanal, coumarin, γ-decyl lactone Cyclopentadecanol, 16-hydroxy-9-hexadecenoic acid lactone, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopentan-γ-2-benzopyran, β-naphthyl methyl ether, ambroxol, dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1b]furan, cypressin, 5-(2,2,3-trimethylcyclopentan-3-enyl)-3-methylpentan-2-ol, 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol, caryophyllenealcohol, tricyclodecene propionate, tricyclodecene acetate, benzyl salicylate, cypressin acetate, and tert-butylcyclohexyl acetate.

[0154] Other fragrances may include essential oils, resins, and resinous odor compounds selected from a variety of sources, such as Peru balsam, frankincense resin, styrax, labdanum resin, nutmeg, cinnamon oil, benzoin resin, coriander, and bright lavender.

[0155] Other suitable fragrances include odor compounds selected from the following: phenethyl alcohol, terpineol, linalool, linalyl acetate, geraniol, nerol, 2-(1,1-dimethylethyl)cyclohexanol acetate, benzyl acetate, and eugenol. Fragrances or flavorings may be used as a single substance or as a mixture of substances with each other.

[0156] Personal care compositions may also contain one or more colorants. Colorants can be pigments, dyes, or mixtures thereof. Non-limiting examples of pigments include titanium dioxide, zinc oxide, kaolin, mica, etc. Non-limiting examples of dyes include food dyes and mixtures thereof suitable for food, pharmaceutical, and cosmetic applications. Some colorants (colorants) are referred to as FD&C dyes.

[0157] The colorant may be present in an amount ranging from about 0.0001 to about 0.4 wt.%, including all percentages and subranges therebetween, based on the total weight of the personal care composition. In some embodiments, the colorant may be present in an amount ranging from about 0.0001 to about 4 wt.%, including all percentages and subranges therebetween, based on the total weight of the personal care composition. In some embodiments, an emulsifier may be added to prevent component separation.

[0158] In other embodiments, the personal composition may contain any of the following materials in any desired amount to achieve the desired effect in the composition (amounts that may be used in some embodiments are provided): one or more basic salts, such as sodium chloride, sodium sulfate, sodium carbonate, sodium bicarbonate and / or their equivalents (0 to 5% by weight); chelating agents, such as tetrasodium EDTA and / or their equivalents (0 to 2% by weight); antimicrobial agents, such as triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether), DMDM ​​hydantoin, formaldehyde and / or imidazolidinyl urea, and / or their equivalents (0 to 2% by weight); organic acids, such as citric acid and / or formic acid and / or their equivalents (0 to 2% by weight); viscosity modifiers (0 to 2% by weight); fragrances and / or perfumes (0 to 5% by weight); preservatives, such as phenoxyethanol, formaldehyde solution, parabens, pentylene glycol or sorbic acid (0 to 2% by weight); pearlescent agents, such as glycol distearate. Distearic esters, such as ethylene glycol distearate and fatty acid monoglycol esters (0 to 3% by weight); stabilizers, such as metal salts of fatty acids, such as magnesium stearate, aluminum stearate and / or zinc stearate (0 to 2% by weight); and dyes and pigments approved for cosmetic use.

[0159] The personal care composition may be aqueous and, for example, contain about 40 to about 90 wt.% water, based on the total weight of the personal care composition. For example, the amount of water present in the personal care composition may be about 50 to 90 wt.%, about 60 to 90 wt.%, about 70 to 90 wt.%, about 80 to 90 wt.%; about 40 to 85 wt.%, about 50 to 85 wt.%, about 60 to 85 wt.%, about 70 to 85 wt.%, about 75 to 85 wt.%; about 40 to 80 wt.%, about 50 to 80 wt.%, about 60 to 80 wt.%, about 70 to 80 wt.%; about 40 to 75 wt.%, about 50 to 75 wt.%, about 60 to 75 wt.%, about 65 to 75 wt.%; about 40 to 70 wt.%, about 50 to 70 wt.%, about 60 to 70 wt.%; about 40 to 60 wt.%, about 50 to 60 wt.%, about 40 to 50 wt.%; about 40 to 50 wt.%; about 50 to 6 ... wt.%, or any range and subrange thereof, based on the total weight of the personal care composition. Example Example 1

[0160] Two personal care compositions (Example Compositions A and B) were prepared according to aspects of the present invention. The formulations of Example Compositions A and B are shown in Table 1. Table 1 Example 2

[0161] The tactile properties of Example Composition B were evaluated by comparing it with a commercially available product (Comparative Composition 1). Comparative Composition 1 has the following ingredient list: water (Aqua / Water / Eau), ethoxydiethylene glycol, ascorbic acid, glycerin, propylene glycol, lauryl ether-23, phenoxyethanol, tocopherol, triethanolamine, ferulic acid, panthenol, and sodium hyaluronate.

[0162] The oiliness, wettability, residue, residual oiliness, and odor of Example Composition B and Comparative Composition 1 were evaluated. Specifically, 50 µL of each sample of Example Composition B and Comparative Composition 1 was applied to the back of the hands of five volunteers. The samples were then rubbed 20 times to distribute the samples across the volunteers' hands. To evaluate the residue of Example Composition B and Comparative Composition 1, volunteers waited for their samples to dry and then gently pinched the backs of their hands to feel the residue. To evaluate the odor of Example Composition B and Comparative Composition 1, volunteers smelled the portion of the back of their hands that received their respective samples.

[0163] Volunteers were instructed to grade the assessed properties using a scale of 0 to 10: oiliness (0 for good, 10 for poor); wettability (10 for good, 0 for poor); residue (0 to 8 for good, 8 for poor); residual oiliness (0 for good, 8 for poor); and odor (0 to 10 for good, 10 for poor). The attached figure provides a bar graph summarizing the assessment results of the tactile properties of Example Composition B and Comparative Composition 1. The results are also summarized in Table 2 below. Table 2

Claims

1. A personal care composition comprising: About 0.1 to about 9 wt.% of vitamin E, said vitamin E comprising tocopherol; About 1 to about 10 wt.% of vitamin B, said vitamin B comprising nicotinamide; and Amaranth plant extracts, All weight percentages are based on the total weight of the personal care composition.

2. The personal care composition of claim 1, further comprising: about 0.05 to about 8 wt.% vitamin C, wherein the vitamin C is selected from ascorbate glucoside, ascorbate-2-glucoside, ascorbate acetate, tetrahexyldecyl ascorbate, and combinations of two or more thereof.

3. The personal care composition of claim 2, wherein the vitamin C comprises about 0.05 to about 1 wt.% of tetrahexyldecyl ascorbate.

4. The personal care composition according to any one of the preceding claims, wherein the personal care composition has a weight ratio of α-tocopherol to nicotinamide of about 1:1 to about 1:

11.

5. The personal care composition according to any one of the preceding claims further comprises: one or more short-chain fatty acids and / or their salts, selected from valeric acid, CH3CH2CH2CH2COOH, isovaleric acid, 3-methylbutyric acid, (CH3)2CHCH2COOH, 2-methylpropionic acid, (CH3)2CHCOOH, butyric acid, CH3CH2CH2COOH, CH3CH2COOH, acetic acid, CH3COOH, formic acid, HCOOH, acetic acid, succinic acid, formic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, isovaleric acid, lactic acid, pyruvic acid, derivatives thereof, their salts, and combinations of two or more thereof.

6. The personal care composition according to any one of the preceding claims, further comprising: about 0.05 to about 10 wt.% of polysaccharides, wherein the polysaccharides comprise cellulose, carboxymethyl hydroxyethyl cellulose, cellulose acetate propionate, hydroxyethyl cellulose, hydroxyethyl ethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, methyl hydroxyethyl cellulose, microcrystalline cellulose, sodium cellulose sulfate, gum arabic, agar, alginate, alginic acid, ammonium alginate, amylopectin, calcium alginate, calcium carrageenan, carnitine, carrageenan, dextrin, gelatin, gellan gum, guar gum, guar hydroxypropyltrimethylammonium chloride, lithium montmorillonite, hyaluronic acid, hydrated silica, hydroxypropyl chitosan, hydroxypropyl guar gum, ark pine gum, kelp gum, locust bean gum, natto gum, potassium alginate, potassium carrageenan, propylene glycol alginate, stearin gum, sodium carboxymethyl dextran, carrageenan, tragacanth gum, xanthan gum, biosaccharide gum, inulin, or a combination of two or more thereof.

7. The personal care composition according to any one of the preceding claims further comprises: about 0.01 to about 12 wt.% of a fatty alcohol, wherein the fatty alcohol comprises butyloctanol.

8. The personal care composition according to any one of the preceding claims, wherein the personal care composition is substantially free of or contains no ergothioneine.

9. The personal care composition according to any one of the preceding claims, wherein the personal care composition is substantially free of or free of histidine thiourea derivatives.

10. The personal care composition according to any one of the preceding claims, further comprising: non-short-chain fatty acids, said non-short-chain fatty acids comprising linolenic acid, octadecanoic acid, eicosapentaenoic acid, eicosapentaenoic acid, docosapentaenoic acid, docosahexaenoic acid, linolenic acid, calendulatic acid, eicosadienoic acid, arachidonic acid, docosadienoic acid, adrenaline, octadecanoic acid, docosapentaenoic acid, palmitic acid, palmitoleic acid, stearic acid, oleic acid, isoleic acid, linolenic acid, α-linolenic acid, arachidic acid, or a combination of two or more thereof.

11. The personal care composition of claim 10, wherein the non-short-chain fatty acid comprises an ω-3 fatty acid selected from linolenic acid, octadecanoic acid, eicosapentaenoic acid, eicosapentaenoic acid, docosapentaenoic acid, docosahexaenoic acid, and combinations of two or more thereof.

12. The personal care composition of claim 10 or claim 11, wherein the non-short-chain fatty acid comprises an ω-6 fatty acid selected from linolenic acid, calendula acid, eicosapentaenoic acid, arachidonic acid, docosahexaenoic acid, adrenaline, octoporic acid, docosahexaenoic acid, docosapentaenoic acid, and combinations of two or more thereof.

13. The personal care composition according to any one of claims 10 to 12, wherein the non-short-chain fatty acid comprises oleic acid and linolenic acid, wherein the weight ratio of oleic acid to linolenic acid is from about 1:1 to about 1:

4.

14. A personal care composition comprising: Approximately 0.05 to approximately 5 wt.% polysaccharides; Fatty alcohols: about 0.01 to about 12 wt.%; About 0.05 to about 7 wt.% of short-chain fatty acids and / or their salts; Approximately 0.1 to approximately 9 wt.% of vitamin E; Approximately 1 to approximately 10 wt.% of vitamin B; and Amaranth plant extracts, All weight percentages are based on the total weight of the personal care composition.

15. A personal care composition comprising: Approximately 0.05 to approximately 5 wt.% polysaccharides; Fatty alcohols: about 0.01 to about 12 wt.%; About 0.05 to about 7 wt.% of short-chain fatty acids and / or their salts; Approximately 0.1 to approximately 9 wt.% of vitamin E; Approximately 1 to approximately 10 wt.% of vitamin B; and Approximately 0.05 to approximately 8 wt.% of vitamin C; All weight percentages are based on the total weight of the personal care composition.

16. The personal care composition according to claim 14 or claim 15, wherein the vitamin E is selected from the group consisting of: α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, α-tocotrienol, β-tocotrienol, γ-tocotrienol, δ-tocotrienol, tocopherol acetate, tocopherol phosphate, natural extracts rich in vitamin E derivatives, and combinations of two or more thereof.

17. The personal care composition according to any one of claims 14 to 16, wherein the vitamin B comprises vitamin B3, said vitamin B3 being selected from nicotinic acid esters, non-vasodilating esters of nicotinic acid, nicotinic acid amino acids, nicotinic acid N-oxide, nicotinamide N-oxide, tocopheryl nicotinic acid esters, inositol hexanicotinic acid esters, and combinations of two or more thereof.

18. The personal care composition according to any one of claims 14 to 17, further comprising: an amaranth plant extract containing a variety of ω-3 fatty acids and / or ω-6 fatty acids.

19. The personal care composition according to any one of the preceding claims, further comprising: hyaluronic acid and / or its salts.

20. The personal care composition of claim 19, wherein the hyaluronic acid and / or its salts have an average molecular weight of about 1 Mda to about 4 Mda.

21. The personal care composition according to any one of the preceding claims further comprises: about 1 to about 30 wt.% of a polyol, wherein the polyol comprises one or more diols selected from the group consisting of octyl ethylene glycol, isopentyl glycol, ethylene glycol, propylene glycol, butylene glycol, hexanediol, glycerin, diglycerol, diethylene glycol, dipropylene glycol, and combinations of two or more thereof.

22. The personal care composition according to any one of the preceding claims, further comprising: a soothing agent, wherein the soothing agent comprises bisabolol, aloe vera extract, allantoin, licorice extract, glycyrrhizin, or a combination thereof.