Customized intelligent drug release monitoring trigeminal nerve block microneedle system

Abstract

The invention discloses a customized intelligent drug release monitoring trigeminal nerve block microneedle system, and relates to the technical field of medical equipment. Comprising a radiography mechanism, and the radiography mechanism comprises a workbench, a C-shaped arm, an X-ray bulb tube and an image detector; the head limiting assembly is used for fixing the head of a patient, the positioning assembly is arranged on the head limiting assembly, the positioning assembly comprises an arc-shaped support and a positioning plate used for positioning an oval hole, the positioning plate can be adjusted around the arc-shaped support, a plurality of needle holes are formed in the positioning plate, and the central axis of any needle hole can coincide with the central axis of the oval hole; when the foramen ovale is positioned, a metal probe is inserted into the needle hole, and after positioning is completed, a microneedle for conveying blocking medicine is inserted through the needle hole. According to the microneedle system for customized intelligent drug release monitoring of trigeminal nerve block, after the head of a patient is fixed, the radiography mechanism is matched with the positioning assembly to obtain the position of the foramen foramen ovale, and the accuracy and safety of blocking drug delivery are improved.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a customized intelligent drug release monitoring trigeminal nerve block microneedle system. Background Technology

[0002] Trigeminal neuralgia is a common cranial nerve disorder. Its pathogenesis is often related to factors such as vascular compression of the trigeminal ganglion and demyelinating lesions. Clinically, it mainly manifests as recurrent, severe, and brief episodes of pain in the distribution area of ​​the trigeminal nerve in the face, significantly impacting the patient's quality of life. Trigeminal neuralgia block therapy is currently an important means of controlling pain and curing the disease in clinical practice. It is the mainstream treatment for trigeminal neuralgia. The procedure requires precise location of the percutaneous foramen ovale, through which the blocking medication is then delivered.

[0003] The foramen ovale, as the only bony passage for the trigeminal ganglion to enter and exit the cranial cavity, is located deep at the base of the skull and cannot be directly observed from the surface. It is also adjacent to important anatomical structures such as the internal carotid artery, cavernous sinus, and optic nerve. The accuracy of the puncture path directly determines the safety and treatment effect of the surgery. Once the puncture is deviated, it can easily lead to serious complications such as vascular damage, nerve damage, and intracranial hemorrhage, and even endanger the patient's life.

[0004] In existing technologies, the location of the foramen ovale is mainly obtained by manually puncturing the foramen ovale using fluoroscopic images from a C-arm X-ray machine. Specifically, the doctor obtains fluoroscopic images of the foramen ovale at the base of the skull using a C-arm X-ray machine, determines the puncture point, puncture angle, and puncture depth based on experience, and manually manipulates the puncture needle to perform the puncture. During the puncture, the angle and direction of the puncture needle need to be repeatedly adjusted, and the accuracy of the puncture position is verified by real-time fluoroscopy using a C-arm X-ray machine.

[0005] However, the existing puncture methods have many shortcomings and cannot meet the needs of precision treatment: First, the accuracy of manual puncture is highly dependent on the doctor's clinical experience. Different doctors have different skill levels, which can easily lead to problems such as deviation in puncture angle and improper depth control, resulting in puncture failure or complications, which is not conducive to the standardized implementation of the surgery. The existing C-arm X-ray machine can only provide fluoroscopic images and cannot mechanically limit and guide the puncture path. Doctors need to keep a close eye on the image and manually adjust the puncture needle during the puncture process. The operation is difficult and the hand tremors are likely to occur during long-term operation, which further affects the puncture accuracy. Finally, the existing puncture operation lacks a special positioning component to determine the puncture point and puncture angle. Doctors need to repeatedly probe the position of the foramen ovale with a metal probe. The operation is cumbersome and there is still a risk of puncture deviation during the probe process, which prolongs the operation time and increases the patient's pain and surgical risks.

[0006] Therefore, in response to the technical problems of low accuracy, high difficulty of operation, poor safety and lack of effective positioning and guidance mechanism in the existing percutaneous foramen ovale puncture, the development of a trigeminal nerve block microneedle system that can achieve precise three-dimensional positioning of the foramen ovale, simplify the puncture operation and improve the safety and accuracy of the surgery has become a technical problem that urgently needs to be solved by those skilled in the art. Summary of the Invention

[0007] To address the technical problems existing in the prior art, this application provides a customized intelligent drug release monitoring trigeminal nerve block microneedle system.

[0008] To achieve the above objectives, the technical solution adopted in this application is as follows: a customized intelligent drug release monitoring trigeminal nerve block microneedle system, comprising: an imaging mechanism, which includes a worktable, a C-arm, an X-ray tube, and an image detector. The C-arm is rotatably mounted on the worktable, and the X-ray tube and the image detector are respectively located at both ends of the C-arm. The worktable is also equipped with a display panel for real-time observation of the human facial images acquired by the image detector; and a positioning mechanism, which includes a bed, a head limiting component, and a positioning component for determining the injection point. The head-limiting component, mounted on the bed, is used to fix the patient's head. The positioning component is mounted on the head-limiting component. The positioning component includes an arc-shaped support and a positioning plate for locating the foramen ovale. The positioning plate is adjustable around the arc-shaped support and has several holes for inserting microneedles to deliver the blocking drug. The central axis of any hole can coincide with the central axis of the foramen ovale. When locating the foramen ovale, a metal probe is inserted into the hole. After positioning, the microneedle for delivering the blocking drug is inserted through the hole. The microneedle is equipped with an optical fiber pressure sensor for obtaining the drug delivery pressure.

[0009] In some embodiments of the present invention, the arc-shaped bracket is provided with a groove for adjusting the position of the positioning plate. A sliding mechanism is provided in the groove. The sliding mechanism includes a pulley and a sliding seat. The pulley is symmetrically arranged on both sides of the sliding seat and slides in the groove. The positioning plate is provided at one end of the sliding seat that extends out of the groove.

[0010] In some embodiments of the present invention, the sliding seat is provided with a slide rail for adjusting the distance between the positioning plate and the human face. An adjusting block is provided inside the slide rail. The adjusting block can slide freely along the installation direction of the slide rail. A locking knob is provided on the adjusting block. The positioning plate is disposed on the adjusting block.

[0011] In some embodiments of the present invention, the head limiting component includes uprights, support blocks and trays mounted on the bed, with a limiting gap between the two uprights, the tray being disposed within the limiting gap, and the support block for supporting the back of the human head being disposed on the tray.

[0012] In some embodiments of the present invention, a clamping airbag is provided on the inner side of the positioning plate, and the clamping airbag is used to position the forehead of the human body.

[0013] In some embodiments of the present invention, the above-mentioned arc-shaped bracket is provided with a pump body for inflating the clamping airbag, and the pump body is connected to the clamping airbag.

[0014] In some embodiments of the present invention, the clamping airbag has a strip-shaped heat dissipation groove, and the opening direction of the strip-shaped heat dissipation groove is consistent with the installation direction of the clamping airbag.

[0015] In some embodiments of the present invention, a sensor for acquiring pressure is provided inside the clamping airbag, and the sensor is connected to a display panel.

[0016] Beneficial effects:

[0017] 1. This device is equipped with a positioning mechanism that firmly fixes the patient's head using a head-limiting component, preventing deviation of the puncture path due to head movement during the puncture process and providing a fundamental guarantee for accurate puncture. The positioning component adopts a combination structure of an arc-shaped bracket and an adjustable positioning plate. The arc-shaped bracket adapts to the spherical anatomical shape of the skull base, and the positioning plate can flexibly adjust its angle around the arc-shaped bracket. With the multiple needle holes opened on the positioning plate, the central axis of any needle hole can be precisely aligned with the central axis of the foramen ovale, achieving three-dimensional precise positioning of the foramen ovale. At the same time, by inserting a metal probe into the needle hole for pre-positioning, combined with the verification of C-arm X-ray imaging of the angiography unit, the positioning accuracy is further ensured, effectively avoiding serious complications such as vascular damage and nerve damage caused by deviation of the puncture needle angle or position, significantly improving the safety of the operation.

[0018] 2. This device achieves mechanical limitation and guidance of the puncture path through the needle holes of the positioning plate. After positioning, the microneedle for delivering the blocking drug can be directly inserted along the corresponding needle hole without the need for the doctor to manually and repeatedly adjust the puncture angle and direction based on experience. This effectively solves the problems of high difficulty and high dependence on the doctor's clinical experience in existing manual puncture operations. At the same time, the standardized positioning process and puncture guidance design reduce the impact of differences in the operating skills of different doctors, facilitate the standardization and normalization of the operation, reduce the surgical learning cost, and promote the widespread application of the equipment in clinical practice.

[0019] 3. The C-arm of the angiography unit can rotate flexibly. The X-ray tube and image detector work together to obtain clear fluoroscopic images of the human face and the foramen ovale at the base of the skull. The images are displayed on the display panel in real time, which is convenient for doctors to observe the positioning status in real time. The positioning mechanism works in conjunction with the angiography unit. Doctors can accurately adjust the angle and position of the positioning plate according to the real-time images on the display panel to achieve synchronous verification of positioning and angiography. There is no need to repeatedly probe and compare images, which greatly shortens the operation time, reduces the pain of patients during the operation, and improves the patient's treatment experience. Attached Figure Description

[0020] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0021] Figure 1 This is a structural illustration of an embodiment of this application. Figure 1 ;

[0022] Figure 2 This is a structural illustration of an embodiment of this application. Figure 2 ;

[0023] Figure 3 for Figure 2 A magnified view of a section at point A in the middle;

[0024] Figure 4 This is a side view of an embodiment of this application;

[0025] Figure 5 This is a schematic diagram of the positioning component in an embodiment of this application. Figure 1 ;

[0026] Figure 6 for Figure 5 A magnified view of a section at point B in the middle;

[0027] Figure 7 This is a schematic diagram of the positioning component in an embodiment of this application. Figure 2 ;

[0028] Figure 8 This is a schematic diagram of the sliding mechanism according to an embodiment of this application.

[0029] In the diagram: 1-Workbench; 2-C-arm; 3-X-ray tube; 4-Image detector; 5-Display panel; 6-Bed; 7-Arc-shaped support; 8-Positioning plate; 9-Pinhole; 10-Slide groove; 11-Pulley; 12-Sliding seat; 13-Slide rail; 14-Adjusting block; 15-Locking knob; 16-Upright plate; 17-Support block; 18-Panel; 19-Limiting gap; 20-Clamping airbag; 21-Pump body; 22-Strip heat dissipation groove. Detailed Implementation

[0030] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. The components of the embodiments of this application described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0031] Therefore, the following detailed description of the embodiments of this application provided in the accompanying drawings is not intended to limit the scope of the claimed application, but merely to illustrate selected embodiments of the application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without inventive effort are within the scope of protection of this application.

[0032] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0033] In the description of this application, it should be noted that the use of terms such as "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer" to indicate orientation or positional relationships is based on the orientation or positional relationships shown in the accompanying drawings, or the orientation or positional relationships commonly used when the product is in use. These terms are used solely for the convenience of describing this application and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the use of terms such as "first" and "second" in the description of this application is only used to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0034] Furthermore, the use of terms such as "horizontal" and "vertical" in the description of this application does not imply that the component is required to be absolutely horizontal or suspended, but rather that it may be slightly tilted. For example, "horizontal" simply means that its direction is more horizontal relative to "vertical," and does not mean that the structure must be completely horizontal, but rather that it may be slightly tilted.

[0035] In the description of this application, it should also be noted that, unless otherwise expressly specified and limited, the terms "set up," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0036] Example

[0037] Please refer to Figures 1-8 This embodiment provides a customized intelligent drug release monitoring trigeminal nerve block microneedle system, including: an imaging mechanism, which includes a worktable 1, a C-arm 2, an X-ray tube 3, and an image detector 4. The C-arm 2 is rotatably mounted on the worktable 1, and the X-ray tube 3 and the image detector 4 are respectively located at both ends of the C-arm 2. The worktable 1 is also equipped with a display panel 5 for real-time observation of the human facial images acquired by the image detector 4; and a positioning mechanism, which includes a bed 6, a head limiting component, and a positioning component for determining the injection point. The head limiting component is mounted on the bed 6, and the head is limited... The component is used to fix the patient's head. The positioning component is set on the head limiting component. The positioning component includes an arc-shaped bracket 7 and a positioning plate 8 for positioning the foramen ovale. The positioning plate 8 can be adjusted around the arc-shaped bracket 7. The positioning plate 8 has a plurality of pin holes 9 for inserting microneedles for delivering blocking drugs. The central axis of any pin hole 9 can coincide with the central axis of the foramen ovale. When positioning the foramen ovale, a metal probe is inserted into the pin hole 9. After positioning is completed, a microneedle (not shown in the figure) for delivering blocking drugs is inserted through the pin hole 9. The microneedle is equipped with an optical fiber pressure sensor for obtaining the drug delivery pressure.

[0038] In this embodiment, the workbench 1 serves as the mounting carrier for the C-arm 2 and the display panel 5, providing a stable support foundation for the entire angiography mechanism. The overall height and angle can be adjusted according to surgical needs to adapt to different surgical scenarios. This ensures that all components of the angiography mechanism are firmly installed and operate stably, avoiding image blurring caused by equipment shaking, providing a basic guarantee for accurate observation, and improving the flexibility of equipment operation to adapt to the needs of patients of different heights and positions and surgical procedures.

[0039] The aforementioned C-arm 2 is rotatably mounted on the worktable 1 and can rotate flexibly around the worktable 1, driving the X-ray tubes 3 and image detectors 4 at both ends to rotate synchronously, thereby adjusting the fluoroscopic angle. It can acquire images of the human face and skull base from multiple angles such as lateral and skull base views, ensuring the optimal observation angle for finding the foramen ovale. It solves the problem of the fixed angle and limited observation angle of the existing C-arm 2, and can be flexibly adjusted to the optimal angle for foramen ovale positioning, obtaining clear and comprehensive fluoroscopic images, providing accurate image references for subsequent positioning and puncture, and avoiding positioning errors caused by fluoroscopic deviations.

[0040] The X-ray tube 3 and the image detector 4 are symmetrically arranged at both ends of the C-arm 2, working together to achieve fluoroscopic imaging. The X-ray tube 3 emits X-rays that penetrate the human face and skull base bones. After passing through human tissue, the X-rays are received by the image detector 4, which converts the light signal into an electrical signal and transmits it to the display panel 5. This allows for the rapid and clear acquisition of images of the human face, foramen ovale at the skull base, and surrounding important structures, clearly showing the location and shape of the foramen ovale, facilitating accurate identification of the foramen ovale by doctors. At the same time, the position of the metal probe and puncture needle can be observed in real time, avoiding damage to surrounding blood vessels, nerves, and other important structures during puncture, thus improving the safety of the surgery.

[0041] The aforementioned display panel 5 is mounted on the workbench 1 and electrically connected to the image detector 4. It receives the electrical signals transmitted by the image detector 4 in real time and converts them into a visualized human facial image for doctors to observe in real time. This enables real-time image presentation, allowing doctors to clearly view the location of the foramen ovale, the position of the probe and puncture needle without repeatedly adjusting the patient's position. This simplifies the operation process and facilitates real-time verification of positioning accuracy, timely adjustment of the positioning angle, improved positioning and puncture efficiency, and reduced operational difficulty.

[0042] Furthermore, the aforementioned bed 6 serves as a carrier for the patient and also provides a mounting base for the head restraint component. The height and tilt angle of the bed 6 can be adjusted according to surgical needs to maintain the patient in the optimal puncture position with the head slightly tilted back, providing a comfortable and stable surgical position for the patient. This ensures that the patient's position is fixed during the operation and is also suitable for patients of different heights and body types, improving the versatility of the equipment and providing basic support for head fixation and precise puncture.

[0043] The aforementioned head-limiting component is installed on the bed 6 and adopts an adjustable structure. It firmly fixes the patient's head through the limiting component, restricting the movement of the head in the front-back and left-right directions. It solves the problem in the prior art that the patient's head is prone to movement due to pain or tension, which leads to deviation of the puncture path. It ensures the stability of the head position during the puncture process, provides a basic guarantee for accurate positioning and puncture of the foramen ovale, avoids puncture deviation caused by head movement, and reduces surgical risks.

[0044] Specifically, the aforementioned arc-shaped bracket 7 is fixedly mounted on the head limiting component. Its arc-shaped structure is adapted to the spherical anatomical shape of the human skull base, providing an adjustable mounting base for the positioning plate 8. The positioning plate 8 can be flexibly adjusted around the arc direction of the arc-shaped bracket 7, thereby achieving fine-tuning of the three-dimensional angle. The arc-shaped structure conforms to the anatomical shape of the skull base, making the adjustment of the positioning plate 8 more closely match the anatomical position of the foramen ovale, ensuring that the positioning plate 8 can be accurately aligned with the foramen ovale area. At the same time, it provides stable support for the positioning plate 8, avoiding positioning deviation caused by the shaking of the positioning plate 8, and improving the stability of positioning.

[0045] The aforementioned positioning plate 8 is flexibly adjustable around the arc-shaped support 7. The positioning plate 8 has several pinholes 9. The layout of the pinholes 9 is designed according to the common anatomical location of the foramen ovale. By adjusting the angle of the positioning plate 8, the central axis of any pinhole 9 can be precisely aligned with the central axis of the foramen ovale, achieving precise positioning of the puncture path. The layout of multiple pinholes 9 is adapted to the differences in the anatomical location of the foramen ovale in different patients. Pinholes 9 coaxial with the foramen ovale can be flexibly selected to achieve three-dimensional precise positioning of the foramen ovale. At the same time, the pinholes 9 provide mechanical guidance for the puncture needle, lock the puncture path, avoid deviations caused by manual angle adjustment by the doctor, and greatly improve puncture accuracy.

[0046] During use, the patient lies on the bed 6 with their head secured by a head-limiting component. The C-arm 2 rotates to the optimal fluoroscopic angle, and the X-ray tube 3 and image detector 4 work together to acquire fluoroscopic images of the foramen ovale, which are displayed in real time on the display panel 5. Based on the real-time images, the doctor adjusts the angle of the positioning plate 8 on the arc-shaped support 7 so that the central axis of a certain needle hole 9 on the positioning plate 8 coincides with the central axis of the foramen ovale. A metal probe is inserted into the needle hole 9, and the doctor verifies whether the probe position is aligned with the foramen ovale using the real-time images on the display panel 5, thus completing the positioning. After positioning, the metal probe is removed, and a microneedle for delivering the blocking drug is directly inserted along the needle hole 9 to complete the puncture operation.

[0047] It should be noted that the head limiting component and positioning component mentioned above are made of low-density materials after imaging, such as plastic, while the metal probe is a high-density shadow, to avoid the head limiting component and positioning component affecting the observation during the operation.

[0048] The microneedle used for drug delivery is inserted through a pre-aligned needle hole into the foramen ovale region. Its structure is adapted to the needle hole size, allowing it to travel stably along the central axis of the needle hole, ensuring precise drug delivery to the target area. As the actuating component for drug delivery, the mechanical guidance of the needle hole prevents microneedle deviation, ensuring accurate drug delivery to the trigeminal nerve target area near the foramen ovale, thus improving the therapeutic effect of the blockade. Simultaneously, the microneedle's small size reduces puncture trauma and alleviates patient discomfort.

[0049] The fiber optic pressure sensor integrated on the microneedle is linked with the display panel 5. During drug delivery, it acquires real-time drug delivery pressure data, converts the pressure signal into an electrical signal and transmits it to the display panel, realizing visual monitoring of pressure data. It can capture pressure changes during drug delivery in real time, such as needle blockage, abnormal tissue resistance, and accidental entry into blood vessels.

[0050] Please refer to Figures 5-8In some embodiments of this example, the arc-shaped bracket 7 is provided with a groove 10 for adjusting the position of the positioning plate 8. A sliding mechanism is provided in the groove 10. The sliding mechanism includes a pulley 11 and a sliding seat 12. The pulley 11 is symmetrically arranged on both sides of the sliding seat 12. The pulley 11 is slidably arranged in the groove 10. The positioning plate 8 is arranged at one end of the sliding seat 12 that extends out of the groove 10.

[0051] In this embodiment, the extension direction of the aforementioned groove 10 is consistent with the arc of the arc-shaped support 7, conforming to the spherical anatomical shape of the human skull base, providing a sliding track for the sliding mechanism; the width of the groove 10 is adapted to the size of the pulley 11, ensuring that the pulley 11 can slide flexibly while limiting the lateral displacement of the pulley 11 within the groove 10, ensuring the stability of the sliding process. The aforementioned pulley 11 is symmetrically arranged on both sides of the sliding seat 12, and the wheel surface of the pulley 11 is in contact with the inner wall of the groove 10, adopting a rolling friction structure, which can roll flexibly along the arc direction of the groove 10; the size of the pulley 11 is precisely matched with the groove 10, avoiding jamming or displacement during the sliding process, ensuring smooth and stable rolling. The sliding seat 12 serves as an intermediate carrier connecting the pulley 11 and the positioning plate 8. The pulley 11 is fixed on both sides, one end is embedded in the groove 10, and the other end extends out of the groove 10 and is fixedly connected to the positioning plate 8. The sliding seat 12 can move synchronously along the arc direction of the groove 10 as the pulley 11 rolls, thereby driving the positioning plate 8 to move along the arc direction of the arc-shaped support 7, achieving position adjustment of the positioning plate 8 in three-dimensional space. Simultaneously, the sliding seat 12 can be equipped with a locking component to lock the position after adjustment, preventing displacement of the positioning plate 8. The positioning plate 8 is fixed to the end of the sliding seat 12 extending out of the groove 10. When the sliding seat 12 slides along the groove 10, the positioning plate 8 moves synchronously with the sliding seat 12. Combined with the positioning plate 8's own ability to rotate around the arc-shaped support 7, dual adjustment of the positioning plate 8's arc movement and angular rotation is achieved. Finally, through the coordination of sliding and rotational adjustment, the central axis of any pinhole 9 on the positioning plate 8 can be precisely aligned with the central axis of the oval hole, completing the positioning.

[0052] Please refer to Figures 1-8 In some embodiments of this example, the sliding seat 12 is provided with a slide rail 13 for adjusting the distance between the positioning plate 8 and the human face. An adjusting block 14 is provided inside the slide rail 13. The adjusting block 14 can slide freely along the installation direction of the slide rail 13. A locking knob 15 is provided on the adjusting block 14. The positioning plate 8 is disposed on the adjusting block 14.

[0053] In this embodiment, the slide rail 13 is fixedly installed at one end of the sliding seat 12 extending from the slide groove 10. The installation direction of the slide rail 13 is perpendicular to the human face, that is, it extends along the direction of approaching / moving away from the human face, providing a sliding track for the adjustment block 14. The length of the slide rail 13 is designed according to the commonly used clinical spacing range to adapt to the differences in the distance between the face and the foramen ovale of different patients. The groove width of the slide rail 13 is precisely matched with the size of the adjustment block 14, limiting the left and right deviation of the adjustment block 14 during sliding and ensuring the stability of the spacing adjustment. The adjustment block 14 is embedded in the slide rail 13 and can slide freely along the installation direction of the slide rail 13. The positioning plate 8 is fixedly connected to the adjustment block 14. The sliding of the adjustment block 14 can simultaneously drive the positioning plate 8 to approach or move away from the human face, thereby adjusting the distance between the positioning plate 8 and the human face. The connection between the adjustment block 14 and the slide rail 13 adopts a smooth structure to ensure smooth and non-jamming sliding, and can also cooperate with the locking knob 15 to achieve position locking.

[0054] Please refer to Figures 1-4 In some embodiments of this example, the head limiting component includes upright plates 16, support blocks 17 and trays 18 that are mounted on the bed 6. A limiting gap 19 is provided between the two upright plates 16, and the trays 18 are disposed within the limiting gap 19. The support blocks 17 for supporting the back of the human head are disposed on the trays 18.

[0055] In this embodiment, the two upright plates 16 are supported on the bed frame 6, forming rigid boundaries on the left and right sides. The limiting gap 19 reserved between them is designed to fit the width of a standard human skull. When the patient is supine, the head is naturally placed in the limiting gap 19. The inner walls of the upright plates 16 on the left and right sides, along with the patient's temporal sides, restrict the left and right movement of the head, preventing deviation of the puncture path due to head tilting or swaying during the puncture process. The support plate 18 is set in the limiting gap 19 between the two upright plates 16, and its position usually corresponds to the occipital region when the patient is supine. The support block 17 is fixedly installed on the support plate 18 and is located on the upper part or inner side of the support plate 18, specifically for supporting the occipital protuberance of the human head. The support block 17 has a concave structure that conforms to the contour of the back of the human head to increase the contact area, improve comfort, and increase friction. The support plate 18 serves as a load-bearing base, used to transfer the head weight borne by the support block 17 to the bed body 6, thereby providing vertical upward support for the head.

[0056] Example 2

[0057] Please refer to Figures 1-8Based on Example 1, in order to solve the problem of head tilting and shifting due to the original method of relying solely on the left and right limit of the upright plate 16 and the support block 17 to support the back of the head, and to further improve the stability of head fixation, so as to provide a more reliable basis for subsequent accurate positioning and puncture of the foramen ovale, the inner side of the above-mentioned arc-shaped bracket 7 is provided with a clamping airbag 20, which is used to position the forehead of the human body.

[0058] In this embodiment, the clamping airbag 20 is fixedly installed on the inner side of the arc-shaped bracket 7, with the installation position corresponding to the forehead of the human body, and avoiding the adjustment path of the positioning plate 8 and the area of ​​the needle hole 9, so as to avoid obstructing the positioning plate 8 and interfering with the multi-dimensional adjustment of the positioning plate 8, while not affecting the insertion operation of the puncture needle; the connection between the clamping airbag 20 and the arc-shaped bracket 7 is firmly fixed to ensure that the clamping airbag 20 does not fall off or shift during inflation, deflation and limiting, and forms an integrated structure with the arc-shaped bracket 7, which does not move with the adjustment of the positioning plate 8, and always maintains a fixed posture aligned with the forehead of the human body, providing a stable installation foundation for the front and rear forced limiting.

[0059] Please refer to Figure 7 Furthermore, the aforementioned arc-shaped bracket 7 is provided with a pump body 21 for inflating the clamping airbag 20, and the pump body 21 is connected to the clamping airbag 20.

[0060] In this embodiment, the pump body 21 is fixedly mounted on the arc-shaped bracket 7. The installation position avoids the adjustment path of the positioning plate 8, the area of ​​the pinhole 9, and the range of motion of the patient's head. It adopts an embedded installation method to ensure that the pump body 21 and the arc-shaped bracket 7 form an integrated structure. It will not shift or shake when the positioning plate 8 is adjusted or when the clamping airbag 20 is inflated or deflated, providing stable power support for the inflation of the clamping airbag 20. The pump body 21 adopts a micro controllable pump structure, which is small in size and easy to operate. It integrates an inflation control switch, which can accurately adjust the inflation rate and inflation volume. It is also equipped with a pressure relief valve to realize integrated control of inflation and deflation, which can meet the needs of rapid inflation limit during surgery and rapid deflation and repositioning after surgery. The pump body 21 is sealed to the clamping airbag 20 inside the arc-shaped bracket 7 through a dedicated sealed inflation pipeline. The pipeline layout fits the contour of the arc-shaped bracket 7 and is installed in a hidden manner. The connection uses a sealed joint to ensure no air leakage and no pressure loss during inflation, realizing precise gas transmission between the pump body 21 and the clamping airbag 20.

[0061] Please refer to Figure 7 Furthermore, the aforementioned clamping airbag 20 has a strip-shaped heat dissipation groove 22, and the opening direction of the strip-shaped heat dissipation groove 22 is consistent with the installation direction of the clamping airbag 20.

[0062] It should be noted that during the surgery, the clamping airbag 20 needs to be in close contact with the patient's forehead skin for an extended period. With almost no gap between the clamping airbag 20 and the skin, heat from the skin surface cannot dissipate quickly, leading to heat buildup and sweating on the patient's forehead. This not only reduces patient comfort but may also cause the clamping airbag 20 to slip, affecting friction and reducing positioning stability. The strip-shaped heat dissipation groove 22, on the other hand, is used to create a heat dissipation channel between the clamping airbag 20 and the skin. Because the heat dissipation groove is strip-shaped and extends along the installation direction of the clamping airbag 20, it can effectively dissipate heat from the clamping airbag 20. The airbag 20 forms a parallel, breathable, and heat-dissipating gap with the forehead skin. On the one hand, air can circulate within the gap, carrying away the heat generated on the skin surface to achieve rapid heat dissipation and prevent heat accumulation. On the other hand, sweat can be discharged through the heat dissipation grooves, keeping the contact surface between the skin and the clamping airbag 20 dry, maintaining the friction between the two, and further improving the stability of the clamping and limiting position. At the same time, the strip structure of the heat dissipation grooves will not damage the overall flexibility and fit of the clamping airbag 20, and will not affect the transmission of bidirectional clamping force, ensuring that the limiting effect is not affected.

[0063] Please refer to Figure 1 Furthermore, the aforementioned clamping airbag 20 is equipped with a sensor (not shown in the figure) for acquiring pressure, and the sensor is connected to the display panel 5.

[0064] In this embodiment, the aforementioned pressure sensor is used for real-time monitoring and accurate feedback. It is embedded inside the airbag to capture pressure changes during the inflation and deflation of the airbag 20 in real time, converts the pressure signal into an electrical signal, and transmits it to the display panel 5 through a signal transmission line to visualize the pressure data. This provides doctors with an intuitive pressure reference, avoiding problems caused by improper force due to inflating based on experience. At the same time, it can realize dynamic pressure replenishment or depressurization to ensure that the clamping force is always within a reasonable range, taking into account both fixation stability and patient comfort.

[0065] The above description is merely a preferred embodiment of this application and is not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A customized intelligent drug release monitoring trigeminal nerve block microneedle system, characterized in that, include: The imaging mechanism includes a worktable (1), a C-arm (2), an X-ray tube (3), and an image detector (4). The C-arm (2) is rotatably mounted on the worktable (1). The X-ray tube (3) and the image detector (4) are respectively mounted at both ends of the C-arm (2). The worktable (1) is also provided with a display panel (5) for real-time observation of the human face image acquired by the image detector (4). The positioning mechanism includes a bed (6), a head limiting component, and a positioning component for determining the injection point. The head limiting component is disposed on the bed (6) and is used to fix the patient's head. The positioning component is disposed on the head limiting component. The positioning component includes an arc-shaped bracket (7) and a positioning plate (8) for positioning the foramen ovale. The positioning plate (8) is adjustable around the arc-shaped bracket (7). The positioning plate (8) has a plurality of needle holes (9) for inserting microneedles for delivering blocking drugs. The central axis of any of the needle holes (9) can coincide with the central axis of the foramen ovale. During the positioning of the foramen ovale, a metal probe is inserted into the needle hole (9). After positioning is completed, a microneedle for delivering blocking drugs is inserted through the needle hole (9). The microneedle is equipped with an optical fiber pressure sensor for obtaining the drug delivery pressure.

2. The customized intelligent drug release monitoring trigeminal nerve block microneedle system according to claim 1, characterized in that, The arc-shaped bracket (7) is provided with a groove (10) for adjusting the position of the positioning plate (8). A sliding mechanism is provided in the groove (10). The sliding mechanism includes a pulley (11) and a sliding seat (12). The pulley (11) is symmetrically arranged on both sides of the sliding seat (12). The pulley (11) is slidably arranged in the groove (10). The positioning plate (8) is located at one end of the sliding seat (12) that extends out of the groove (10).

3. The customized intelligent drug release monitoring trigeminal nerve block microneedle system according to claim 2, characterized in that, The sliding seat (12) is provided with a slide rail (13) for adjusting the distance between the positioning plate (8) and the human face. An adjustment block (14) is provided inside the slide rail (13). The adjustment block (14) can slide freely along the installation direction of the slide rail (13). A locking knob (15) is provided on the adjustment block (14). The positioning plate (8) is located on the adjustment block (14).

4. The customized intelligent drug release monitoring trigeminal nerve block microneedle system according to claim 1, characterized in that, The head limiting component includes uprights (16), support blocks (17) and trays (18) mounted on the bed (6). A limiting gap (19) is provided between the two uprights (16), and the trays (18) are located within the limiting gap (19). The support blocks (17) for supporting the back of the human head are located on the trays (18).

5. The customized intelligent drug release monitoring trigeminal nerve block microneedle system according to claim 4, characterized in that, The inner side of the arc-shaped bracket (7) is provided with a clamping airbag (20), which is used to position the forehead of the human body.

6. The customized intelligent drug release monitoring trigeminal nerve block microneedle system according to claim 5, characterized in that, The arc-shaped bracket (7) is provided with a pump body (21) for inflating the clamping airbag (20), and the pump body (21) is connected to the clamping airbag (20).

7. The customized intelligent drug release monitoring trigeminal nerve block microneedle system according to claim 6, characterized in that, The clamping airbag (20) has a strip-shaped heat dissipation groove (22), and the opening direction of the strip-shaped heat dissipation groove (22) is consistent with the installation direction of the clamping airbag (20).

8. The customized intelligent drug release monitoring trigeminal nerve block microneedle system according to claim 7, characterized in that, The clamping airbag (20) is equipped with a sensor for obtaining pressure, and the sensor is connected to the display panel (5).

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