Single-point pulse ablation pressure catheter and single-point pulse ablation equipment

Abstract

The invention discloses a single-point pulse ablation pressure catheter and single-point pulse ablation device.The single-point pulse ablation pressure catheter comprises a front-end electrode, a pressure sensing assembly and a catheter body, the front-end electrode is arranged at the far end of the catheter body, and the pressure sensing assembly comprises a main body structure; two ends of the main body structure are respectively connected with the front end electrode and the tube body; one or more than two axial accommodating grooves and one circumferential annular groove are formed in the periphery of the main body structure, and the accommodating grooves are intersected with the annular groove.

Description

Technical Field

[0001] This application relates to the field of medical catheter technology, specifically to a single-point pulse ablation pressure catheter and a single-point pulse ablation device. Background Technology

[0002] Atrial fibrillation (AF) is a common arrhythmia. Radiofrequency ablation and cryoablation are two commonly used clinical methods for treating arrhythmias such as AF. Ablation damage must be sufficient to destroy the arrhythmic tissue or substantially interfere with or isolate the abnormal electrical conduction within the myocardium. However, excessive ablation can affect surrounding healthy tissue and nerve tissue. Radiofrequency ablation, with its point-by-point ablation procedure, is time-consuming, requires a high level of catheter manipulation skill from the operator, causes patient discomfort during the procedure, and is prone to pulmonary vein stenosis post-procedure. Radiofrequency ablation can damage the cardiac endothelial surface, activate the extrinsic coagulation cascade, and lead to pyrolysis and thrombus formation, which can further lead to systemic thromboembolism. Simultaneously, applying radiofrequency energy to the target tissue can affect non-target tissues; applying radiofrequency energy to the atrial wall tissue may cause esophageal or nerve damage. Furthermore, radiofrequency ablation can also lead to tissue scarring, further contributing to embolic problems. Cryoablation has a higher rate of phrenic nerve injury, and freezing of the epicardium near the coronary arteries can lead to thrombosis and progressive coronary artery stenosis.

[0003] Single-point ablation also has its advantages in atrial fibrillation surgery. The operation of single-point ablation can concentrate energy on the head electrode, which has a good ablation effect on thicker myocardial tissue. At the same time, the single-point ablation mode also makes it easy to perform supplementary ablation at the exposed point during ablation.

[0004] The latest technique for treating atrial fibrillation is high-voltage pulsed electric field (PLPF) ablation. This technique applies a brief pulse of high voltage to tissue cells, generating a localized high-voltage electric field of several hundred volts per centimeter. This localized high-voltage electric field exceeds the cell's voltage penetration threshold, creating irreversible perforations in the cell membrane to disrupt it. This allows for the exchange of biomolecules across the cell membrane, leading to cell necrosis or apoptosis. Because different tissue cells have different voltage penetration thresholds, PPF ablation can be selectively applied to cardiomyocytes (with relatively low thresholds) without affecting other non-target tissues (such as nerves, esophagus, blood vessels, and blood). Furthermore, the energy release time during pulsed electric field application is very short, without thermal effects, thus avoiding tissue damage, pulmonary vein stenosis, and other problems. Therefore, pulsed ablation is a non-thermal technique; the damage mechanism involves creating nanoscale micropores in certain cell membranes through high-frequency electrical pulses. The potential advantages of pulsed ablation for atrial fibrillation include: ① tissue selectivity, protecting surrounding tissues from damage; ② rapid release of the pulsed electric field within seconds; ③ no coagulative necrosis, reducing the risk of pulmonary vein (PV) stenosis.

[0005] To achieve rapid ablation, current pulse ablation catheters employ multi-point simultaneous ablation modes such as ring-shaped, petal-shaped, or balloon-shaped catheters. However, due to the varying shapes of pulmonary vein openings, the electrode arm is prone to deformation or poor fit when placed near the pulmonary vein opening, making it difficult to achieve proper fit. In such cases, multi-point pulse ablation can easily lead to missed spots. Summary of the Invention

[0006] This application provides a single-point pulse ablation pressure catheter to replace single-point radiofrequency ablation without altering the operator's usual single-point ablation techniques. It also addresses the issues of esophageal or nerve damage when using radiofrequency energy in thin myocardial tissue and leakage points at irregularly shaped pulmonary vein orifices.

[0007] The technical solution of this application is as follows: 1. A single-point pulse ablation pressure catheter, comprising a front electrode, a pressure sensing component, and a tube body, wherein the front electrode is disposed at the distal end of the tube body, and the pressure sensing component comprises a main structure, wherein both ends of the main structure are respectively connected to the front electrode and the tube body. One or more axially oriented receiving grooves and a circumferentially oriented annular groove are provided on the outer periphery of the main structure, and the receiving grooves intersect with the annular groove.

[0008] 2. The single-point pulse ablation pressure catheter according to item 1, wherein one or two ring electrodes are sleeved on the tube body, and the distance between any one of the ring electrodes and the front electrode is greater than 3 mm.

[0009] 3. The single-point pulse ablation pressure catheter according to item 1, wherein the axial height of the annular groove is 0.2-1 mm.

[0010] 4. The single-point pulse ablation pressure catheter according to item 1, wherein the radial depth of the annular groove is 0.5-1 mm.

[0011] 5. The single-point pulse ablation pressure catheter according to item 1, wherein the annular groove is located in the middle of the main structure.

[0012] 6. The single-point pulse ablation pressure catheter according to item 1, wherein each of the receiving grooves includes a first receiving unit and a second receiving unit, the first receiving unit and the second receiving unit being located on both sides of the annular groove, respectively.

[0013] 7. The single-point pulse ablation pressure conduit according to item 6, wherein a first optical fiber is disposed in the first receiving unit, a second optical fiber is disposed in the second receiving unit, and the head end of the first optical fiber is disposed opposite to the head end of the second optical fiber.

[0014] 8. The single-point pulse ablation pressure catheter according to item 1, wherein one end of the main structure extends into the front electrode; The main structure is a hollow structure, and the inner wall of the main structure has an annular snap-fit ​​ring.

[0015] 9. The single-point pulse ablation pressure catheter according to item 8, wherein the tube body is provided with a connecting component at one end near the front electrode, the connecting component having a large-diameter end and a small-diameter end, the large-diameter end being sleeved on one end of the tube body, and the small-diameter end being sleeved inside the main structure and in contact with the snap ring.

[0016] 10. The single-point pulse ablation pressure catheter according to item 9, wherein a hollow structure is provided on the large-diameter end, and the first optical fiber extends into the tube body through the hollow structure.

[0017] 11. A single-point pulse ablation device, comprising the single-point pulse ablation pressure catheter as described in any one of claims 1-10.

[0018] The single-point pulse ablation pressure catheter of this application has one or more axially oriented receiving grooves on the outer periphery of the main structure, and only one circumferential annular groove on the outer periphery of the main structure. A first optical fiber and a second optical fiber are arranged in the receiving groove, and the first optical fiber and the second optical fiber are respectively located on the upper and lower sides of the annular groove. The light emitted by the first optical fiber is reflected back into the first optical fiber through the second optical fiber. Thus, the pressure sensing component can better sense the force in different directions through the different effects of reflected light signals. Since only one circumferential annular groove is provided on the outer periphery of the main structure, the axial dimension of the main structure is shorter, which is more conducive to accurately reaching the lesion site and making the operation more flexible. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the single-point pulse ablation pressure catheter of this application.

[0020] Figure 2 This is a schematic diagram of the single-point pulse ablation pressure catheter of this application.

[0021] Figure 3 This is a schematic diagram of the single-point pulse ablation pressure catheter of this application.

[0022] Figure 4 This is a schematic diagram of the main structure of the pressure sensing component of this application.

[0023] Figure 5 This is a schematic diagram of the main structure of the pressure sensing component of this application.

[0024] Figure 6This is a schematic diagram of the front-end electrode structure of this application.

[0025] Explanation of reference numerals in the attached figures: 1-Front-end electrode, 2-Main structure, 3-First optical fiber, 4-First ring electrode, 5-Hose segment, 6-Main tube segment, 7-First receiving unit, 8-Second ring electrode, 9-Second optical fiber, 10-Annular groove, 11-Connecting assembly, 12-Main channel, 13-Secondary channel, 14-Snap-fit ​​ring, 15-Receiving groove, 16-Second receiving unit, 17-Opening groove. Detailed Implementation

[0026] The following description provides exemplary embodiments of this application, including various details to aid understanding, and should be considered merely exemplary. Therefore, those skilled in the art will recognize that various changes and modifications can be made to the embodiments described herein without departing from the scope and spirit of this application. Similarly, for clarity and brevity, descriptions of well-known functions and structures are omitted in the following description.

[0027] It should be noted that certain terms are used in the specification and claims to refer to specific components. Those skilled in the art will understand that different terms may be used to refer to the same component. This specification and claims do not distinguish components based on differences in terminology, but rather on differences in function. The terms "comprising" or "including" used throughout the specification and claims are open-ended and should be interpreted as "comprising but not limited to." The following descriptions in the specification are preferred embodiments for carrying out this application; however, these descriptions are for the purpose of understanding the general principles of the specification and are not intended to limit the scope of this application. The scope of protection of this application shall be determined by the appended claims.

[0028] In interventional medicine, the end closer to the operator is defined as the "proximal end," and the end farther from the operator is defined as the "distal end." For elongated objects, the direction parallel to their length is defined as the "axial direction." For objects with a circular cross-section, the direction surrounding their axis is defined as the "circumferential direction." For cylindrical objects, their extension direction is defined as the "axial direction," and the radial direction of the circular cross-section is defined as the "radial direction."

[0029] This application provides a single-point pulse ablation pressure catheter, which includes a front electrode 1, a pressure sensing component, and a tube body. The front electrode 1 is disposed at the distal end of the tube body. The pressure sensing component includes a main structure 2, and the two ends of the main structure 2 are respectively connected to the front electrode 1 and the tube body. One or more axially oriented receiving grooves 15 and a circumferentially oriented annular groove 10 are provided on the outer periphery of the main structure 2, and the receiving grooves 15 and the annular groove 10 intersect.

[0030] Furthermore, the front end electrode 1 has a distal end and a proximal end, the distal end and the proximal end are integrally formed and coaxial, and the radial dimension of the distal end is greater than or equal to the radial dimension of the proximal end.

[0031] like Figure 6 As shown, both the proximal and distal ends can be columnar structures. Within the proximal end, the end furthest from the distal end has an opening groove 17, and the bottom of the opening groove 17 has one or more main connecting holes. The front electrode 1 has a main channel 12 arranged axially to connect the proximal and distal ends, and the main channel 12 communicates with the main connecting holes, meaning the main connecting holes extend axially into the proximal and distal ends to form the main channel 12.

[0032] A pulse ablation wire is placed inside the main channel 12.

[0033] Furthermore, the bottom shape of the opening groove 17 can be circular, elliptical, n-sided (n≥3), etc.

[0034] Furthermore, at the bottom of the opening groove 17, there is a secondary communication hole surrounding the main communication hole. The secondary communication hole extends axially into the proximal end to form a secondary channel 13, and the secondary channel 13 does not extend into the distal end.

[0035] The secondary channel 13 is equipped with a thermocouple, which can sense the temperature change of the pressure sensing component and provide temperature compensation to the pressure sensing component, making the test results of the pressure sensing component more accurate.

[0036] The front electrode 1 can be made of platinum-iridium alloy, which has good energy conductivity, making the ablation process more efficient.

[0037] Furthermore, the axial height of the annular groove 10 is 0.2-1 mm, for example, it can be 0.2 mm, 0.25 mm, 0.3 mm, 0.35 mm, 0.4 mm, 0.45 mm, 0.5 mm, 0.55 mm, 0.6 mm, 0.65 mm, 0.7 mm, 0.75 mm, 0.8 mm, 0.85 mm, 0.9 mm, 0.95 mm, 1 mm, etc. If the axial height of the annular groove 10 is too high, it will affect the reflection and attenuation of light, making the transmitted force value inaccurate; if its height is too low, it will cause the light reflection to be lost, and the optical fiber will not receive the reflected light signal.

[0038] Furthermore, the radial depth of the annular groove 10 is 0.5-1mm, for example, it can be 0.5mm, 0.55mm, 0.6mm, 0.65mm, 0.7mm, 0.75mm, 0.8mm, 0.85mm, 0.9mm, 0.95mm, 1mm, etc. If the radial depth of the annular groove 10 is too deep, the supporting force of the main structure 2 will be insufficient, and it will deform under slight stress and cannot recover, thus failing. If it is too shallow, the end face of the first optical fiber will be blocked, and the complete optical signal cannot be transmitted.

[0039] Furthermore, such as Figure 4 As shown, the annular groove 10 is located in the middle of the main structure 2.

[0040] Furthermore, the number of the receiving slots 15 can be 1, 2, 3, 4, 5, 6, 7, 8, 9, etc., which can be determined according to actual needs.

[0041] like Figure 5 As shown, there are three receiving grooves 15, and the three receiving grooves 15 are equally spaced along the axial direction of the main body structure 2. That is, the three receiving grooves 15 are evenly arranged circumferentially at 120 degrees to ensure that the contact force in all directions can be detected evenly. The magnitude of the force is measured by the deformation of the annular groove 10 of the main body structure 2. In order to better transmit the force, the front electrode 1 and the main body structure 2 must be rigidly connected to reduce the force transmission loss.

[0042] Furthermore, each of the receiving grooves 15 includes a first receiving unit 7 and a second receiving unit 16, the first receiving unit 7 and the second receiving unit 16 being located on both sides of the annular groove 10, respectively.

[0043] The first receiving unit 7 contains a first optical fiber 3, and the second receiving unit 16 contains a second optical fiber 9, with the tips of the first optical fiber 3 and the tips of the second optical fiber 9 positioned opposite each other. Light emitted from the tip of the first optical fiber 3 directly illuminates the tip of the second optical fiber 9 and is reflected at the tip of the second optical fiber 9, thus being received again by the first optical fiber 3. Since the main structure 2 has multiple receiving slots 15, each containing a corresponding first optical fiber 3 and second optical fiber 9, the pressure sensing component can better sense forces in different directions by observing the different effects of reflected light signals.

[0044] Furthermore, one end of the main body structure 2 extends into the front-end electrode 1, that is, one end of the main body structure 2 extends into the opening groove 17 of the front-end electrode 1. This design allows for a more secure connection between the main body structure 2 and the front-end electrode 1, thereby enabling more precise force transmission.

[0045] The main structure 2 is made of metal. To improve the accuracy of the single-point pulse ablation pressure catheter detection force, the main structure 2 should be made of a metal with a low thermal influence coefficient to reduce the impact of the metal's thermal expansion coefficient on light transmission. For example, the material of the main structure 2 can be pure titanium, nickel-titanium, high-elasticity stainless steel, etc.

[0046] The length of the main structure is 1.1-2.5 mm. With this configuration, if the length of the main structure is too short, the required receiving grooves for placing the first and second optical fibers cannot be achieved in the manufacturing process; if it is too long, the length of the non-adjustable section at the front end of the catheter will be increased, which will affect the accuracy of the catheter reaching the lesion site.

[0047] Furthermore, in order to improve the accuracy of the single-point pulse ablation pressure catheter detection force and prevent the influence of external temperature on the first optical fiber 3, a temperature sensor is installed inside the main structure 2 to detect the temperature of the main structure 2 in real time.

[0048] Furthermore, such as Figure 5 As shown, the main structure 2 is a hollow structure, and the inner wall of the main structure 2 has an annular snap-fit ​​ring 14.

[0049] The ratio of the inner diameter to the outer diameter of the snap ring 14 is (0.8-1.5):2.2, preferably 1:2.2. This design can ensure the smooth passage of internal wires and thermocouples, and also ensure that the snap ring 14 is not easily deformed under force.

[0050] Specifically, the ratio of the inner diameter to the outer diameter of the snap ring 14 can be 0.8:2.2, 0.9:2.2, 1:2.2, 1.1:2.2, 1.2:2.2, 1.3:2.2, 1.4:2.2, 1.5:2.2, etc.

[0051] Furthermore, the tube body has a connecting component 11 at one end near the front electrode 1. The connecting component 11 has a large-diameter end and a small-diameter end. The large-diameter end is fitted onto one end of the tube body, and the small-diameter end is fitted into the main body structure 2, contacting the retaining ring 14. The inner diameter of the retaining ring 14 is larger than the equivalent outer diameter of the small-diameter end; the retaining ring 14 is used to limit the position of the connecting component 11 extending into the main body structure 2.

[0052] The large-diameter end and the small-diameter end are coaxial, and both the large-diameter end and the small-diameter end are columnar structures.

[0053] The equivalent diameter of the larger diameter end is greater than the equivalent diameter of the smaller diameter end.

[0054] Furthermore, a hollow structure is provided on the large-diameter end, through which the first optical fiber 3 extends into the tube body.

[0055] Furthermore, one or more ring electrodes are fitted onto the tube body, and the distance between any one of the ring electrodes and the front electrode 1 is greater than 3 mm. This design helps to improve the bipolar pulse ablation depth. The two or more ring electrodes fitted onto the tube body are for using time-stamped measurements of intracardiac electrical signals to locate lesions.

[0056] The distance between any one of the ring electrodes and the front end electrode 1 can be 4mm, 4.2mm, 4.5mm, 4.8mm, 5mm, 5.5mm, 6mm, 6.5mm, 7mm, 8mm, etc.

[0057] The number of ring electrodes can be 2, 3, 4, 5, or more, and the number of ring electrodes can be determined according to actual needs.

[0058] like Figures 1-3 As shown, there are two ring electrodes, namely a first ring electrode 4 and a second ring electrode 8. The first ring electrode 4 is located close to the connecting component 11, and the second ring electrode 8 is located on the side of the first ring electrode 4 away from the connecting component 11. The distance between the first ring electrode 4 and the front end electrode 1 is greater than 3mm, for example, it can be 4mm, 5mm, 6mm, 7mm, 8mm, 9mm, 10mm, 11mm, 12mm, 13mm, 14mm, etc.

[0059] In some implementations, the distance between the front electrode 1 and the first ring electrode 4 is 5-8 mm in order to ensure a good ablation effect.

[0060] In some embodiments, in order to ensure that the front electrode 1 and the first ring electrode 4 achieve a good ablation effect, the length of the front electrode 1 is 2-4 mm, for example, it can be 2 mm, 2.1 mm, 2.2 mm, 2.3 mm, 2.4 mm, 2.5 mm, 2.6 mm, 2.7 mm, 2.8 mm, 2.9 mm, 3 mm, 3.1 mm, 3.3 mm, 3.4 mm, 3.5 mm, 3.6 mm, 3.7 mm, 3.8 mm, 3.9 mm, 4 mm, etc., and the length of the first ring electrode 4 is 2-3 mm, for example, it can be 2 mm, 2.1 mm, 2.2 mm, 2.3 mm, 2.4 mm, 2.5 mm, 2.6 mm, 2.7 mm, 2.8 mm, 2.9 mm, 3 mm, etc.

[0061] The first ring electrode 4 and the second ring electrode 8 can be made of platinum-iridium alloy, which has good energy conductivity, making the ablation process more efficient.

[0062] Since the front electrode 1 forms a double-pulse electric field with at least two ring electrodes, this catheter effectively compensates for the problems of pure radiofrequency ablation catheters causing esophageal or nerve damage in thin myocardial tissue and pure pulse ablation catheters not penetrating in thick myocardial tissue without changing any of the operator's operating habits. At the same time, it greatly reduces the operation time and solves the problem of easy missed points when ablating irregular pulmonary vein openings.

[0063] Furthermore, the tube body includes a flexible tube segment 5 and a main tube segment 6. The connecting assembly 11 and the tube body in contact with the ring electrode are both flexible tube segments 5. The main tube segment 6 is connected to the end of the flexible tube segment 5 that is away from the ring electrode and the connecting assembly 11.

[0064] To improve the accuracy of the detection force, the flexible tube segment 5 must be sufficiently flexible, preferably with a Shore hardness of 30D or less, to reduce force transmission loss. At the same time, the flexible tube segment 5 must also ensure good sealing to maintain good sealing after the catheter enters the human body.

[0065] The single-point pulse ablation pressure catheter of this application, during the procedure, forms a pulse circuit through the ring electrode and the front electrode for pulse ablation. The catheter contains a pressure sensing component that can reflect the magnitude and direction of the force when the catheter is placed against the atrium in real time, thereby helping the operator to control the catheter and its contact with the atrium for better ablation. In addition, the catheter also contains a magnetic positioning sensor, which can display the ablation position in real time, facilitating continuous ablation. Compared with general pressure catheters, the single-point pulse ablation pressure catheter of this application has a smaller main structure for the pressure sensing component, and a shorter length of the non-adjustable section at the front end of the main structure, which is more conducive to accurately reaching the lesion site and more flexible control. The fixed connection method between the pressure sensing component and the front electrode further facilitates force transmission, making pressure measurement more accurate. Furthermore, the reasonable size and spacing of the front electrode and ring electrode allow for deeper pulse ablation depth.

[0066] This application also provides a single-point pulse ablation device, which includes a single-point pulse ablation pressure conduit and a pressure monitoring device. The pressure monitoring device can convert different light signals reflected inside the single-point pulse ablation pressure conduit into force values, so that the device can better sense forces in different directions.

[0067] Example The materials and test methods used in the embodiments of this application are described in a general and / or specific manner. In the following embodiments, unless otherwise specified, % represents wt%, i.e., weight percentage. Reagents or instruments used, unless otherwise specified, are all commercially available conventional reagent products.

[0068] Example 1 This embodiment describes a single-point pulse ablation device, which includes a single-point pulse ablation pressure catheter and a pressure monitoring device. The single-point pulse ablation pressure catheter is as follows: Figure 2-3 As shown, the single-point pulse ablation pressure catheter includes a front electrode 1, a pressure sensing component, a tube body, and two ring electrodes.

[0069] The front-end electrode 1 has a cylindrical distal end and a proximal end, with the distal end and the proximal end coaxial, and the diameter of the distal end being larger than that of the proximal end. Within the proximal end, at the end furthest from the distal end, there is an opening groove 17. The bottom of the opening groove 17 has a main connecting hole and a secondary connecting hole, with the main connecting hole located at the center of the bottom of the opening groove 17. The main connecting hole extends axially into the proximal and distal ends to form a main channel 12, and the secondary connecting hole extends axially into the proximal end to form a secondary channel 13, which does not extend into the distal end. The pressure sensing assembly includes a main body structure 2 (made of titanium). One end of the main body structure 2 extends into the opening groove 17 of the front-end electrode 1, and the other end is connected to the tube body. Three axially spaced receiving grooves 15 and a circumferentially spaced annular groove 10 are provided on the outer periphery of the main body structure 2, and the receiving grooves 15 intersect with the annular groove 10. The annular groove 10 is located in the middle of the main structure 2. Each receiving groove 15 includes a first receiving unit 7 and a second receiving unit 16, which are located on opposite sides of the annular groove 10. A first optical fiber 3 is disposed in the first receiving unit 7, and a second optical fiber 9 is disposed in the second receiving unit 16, with the ends of the first optical fiber 3 and the ends of the second optical fiber 9 facing each other. The main structure 2 is a hollow structure, and its inner wall has an annular retaining ring 14. A temperature sensor is also disposed within the main structure 2. The ratio of the inner diameter to the outer diameter of the retaining ring 14 is 1:2.2. The axial height of the annular groove 10 is 0.2 mm, and the radial depth of the annular groove 10 is 0.7 mm.

[0070] The tube body includes a cylindrical, coaxial flexible tube segment 5 and a main tube segment 6, with the flexible tube segment 5 communicating with the main tube segment 6. A connecting component 11 is provided at one end of the flexible tube segment 5 near the front-end electrode 1. The connecting component 11 has a large-diameter end and a small-diameter end. The large-diameter end is fitted onto one end of the flexible tube segment 5, and the small-diameter end is fitted inside the main body structure 2, contacting the snap-fit ​​ring 14. The diameter of the large-diameter end is larger than the diameter of the small-diameter end. A perforated structure is provided on the end face of the large-diameter end, through which the first optical fiber 3 extends into the flexible tube segment 5.

[0071] The two ring electrodes are a first ring electrode 4 and a second ring electrode 8. The first ring electrode 4 is sleeved on the outer periphery of the flexible tube segment 5 and disposed close to the connecting assembly 11. The second ring electrode 8 is sleeved on the outer periphery of the flexible tube segment 5 and disposed on the side of the first ring electrode 4 away from the connecting assembly 11. The distance between the first ring electrode 4 and the front end electrode 1 is 5 mm. The length of the first ring electrode 4 is 3 mm. The parameters of this embodiment are shown in Table 1.

[0072] The difference between Examples 2-5 and Example 1 is that the distance L1 between the first ring electrode 4 and the front end electrode 1 is different; all other parameters are the same. The parameters for this example are shown in Table 1.

[0073] The difference between Examples 6-9 and Example 1 is that the axial height of the annular groove is the same, while all other parameters are identical. The parameters for this example are shown in Table 1.

[0074] The difference between Examples 10-13 and Example 1 is that the radial depth of the annular groove is the same, while all other parameters are identical. The parameters for this example are shown in Table 1.

[0075] The difference between Examples 14 and 15 and Example 1 is that the radial length of the main structure is the same, while all other parameters are identical. The parameters for this example are shown in Table 1.

[0076] The difference between Comparative Example 1 and Embodiment 1 of this application lies in the number of annular grooves. This comparative example has two annular grooves, with a distance of 15 μm between them. The parameters of this comparative example are shown in Table 1.

[0077] The difference between Comparative Example 2 and Embodiment 1 of this application lies in the number of annular grooves. In this comparative example, there are three annular grooves, which are equally spaced with a spacing of 15 μm. The parameters of this comparative example are shown in Table 1.

[0078] Potato ablation experiment procedure: Potatoes were sliced ​​to a thickness of 2cm ± 0.5cm and placed in physiological saline at 37℃. The single-point pulse ablation pressure catheter of this application was vertically attached to the surface of the potato slice. Then, a 10g weight was tied to the main tube section of the single-point pulse ablation pressure catheter to keep the single-point pulse ablation pressure catheter vertically attached to the surface of the potato slice. At the same time, the pressure monitoring device showed that the force value detected by the single-point pulse ablation pressure catheter was 10g ± 0.5. Then, the ablation device was used to discharge 100 times. After that, the potato slice was removed and left to stand for 24 hours. The ablation point on the potato slice was cut open and the ablation depth was measured with a ruler.

[0079] Force transmission error: Slice potatoes into pieces with a thickness of 2cm ± 0.5cm and place them in a 37℃ saline solution. Place the single-point pulse ablation pressure catheter of this application vertically against the surface of the potato slices. Then, tie a 10g weight to the main body of the single-point pulse ablation pressure catheter, keeping the single-point pulse ablation pressure catheter vertically against the surface of the potato slices. At the same time, the pressure monitoring device displays the force value detected by the single-point pulse ablation pressure catheter as 10g ± 0.5g. Then, perform 100 discharges using the ablation device. During the discharge process, the pressure display device will continuously display the force value detected by the single-point pulse ablation pressure catheter. The force value minus 10g is the force transmission error.

[0080] Table 1 shows the parameters for each embodiment and comparative example.

[0081] Note: L1 is the distance between the first ring electrode and the front end electrode.

[0082] Summary: As shown in Table 1, the single-point pulse ablation pressure catheter of this application, due to the special structure of the pressure sensing component, achieves a deeper ablation depth and a smaller force transmission error. Furthermore, because the main structure has only one circumferential annular groove on its outer periphery, the axial dimension of the main structure is shorter, which further facilitates precise targeting of the lesion. Additionally, when the axial height of the annular groove is too small, the force display may occasionally be interrupted; when the radial depth of the annular groove is too small, no force is displayed; and when the radial depth of the annular groove is too large, the pressure sensing component is prone to deformation.

[0083] In the catheter in Comparative Example 1, the main structure of its pressure sensing component has two annular grooves. The first optical fiber and the corresponding second optical fiber in the two annular grooves are placed symmetrically. The optical fiber sensor composed of the two first optical fibers and the second optical fiber cannot effectively convert the changes in force in each direction, which will lead to a decrease in the accuracy of the force transmission value. As a result, the force value detected by the catheter fluctuates too much and cannot be accurately measured.

[0084] In the catheter of Comparative Example 2, the main structure of its pressure sensing component requires three 0.7mm annular grooves to be made in a 2.5mm space, leaving only 0.4mm margin. Current technology cannot process three consecutive annular grooves in such a close distance. If three annular grooves are to be made on the main structure, the distance between two adjacent annular grooves will increase, which will greatly increase the axial length of the main structure. This will increase the length of the non-adjustable part at the front end of the catheter, and affect the accuracy of the catheter reaching the lesion site.

[0085] The above description is merely a preferred embodiment of this application and is not intended to limit the application in any other way. Any person skilled in the art may make changes or modifications to the disclosed technical content to create equivalent embodiments. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of this application without departing from the scope of the technical solution of this application shall still fall within the protection scope of this application.

Claims

1. A single-point pulse ablation pressure catheter, wherein, It includes a front electrode, a pressure sensing component, and a tube body. The front electrode is disposed at the distal end of the tube body. The pressure sensing component includes a main structure, and the two ends of the main structure are respectively connected to the front electrode and the tube body. One or more axially oriented receiving grooves and a circumferentially oriented annular groove are provided on the outer periphery of the main structure, and the receiving grooves intersect with the annular groove.

2. The single-point pulse ablation pressure catheter according to claim 1, wherein, One or two ring electrodes are sleeved on the tube body, and the distance between any one of the ring electrodes and the front end electrode is greater than 3mm.

3. The single-point pulse ablation pressure catheter according to claim 1, wherein, The axial height of the annular groove is 0.2-1 mm.

4. The single-point pulse ablation pressure catheter according to claim 1, wherein, The radial depth of the annular groove is 0.5-1 mm.

5. The single-point pulse ablation pressure catheter according to claim 1, wherein, The annular groove is located in the middle of the main structure.

6. The single-point pulse ablation pressure catheter according to claim 1, wherein, Each of the aforementioned receiving grooves includes a first receiving unit and a second receiving unit, the first receiving unit and the second receiving unit being located on opposite sides of the annular groove, respectively; Preferably, the first accommodating unit contains a first optical fiber, the second accommodating unit contains a second optical fiber, and the head ends of the first optical fiber and the head ends of the second optical fiber are positioned opposite each other.

7. The single-point pulse ablation pressure catheter according to claim 1, wherein, One end of the main structure extends into the front electrode; The main structure is a hollow structure, and the inner wall of the main structure has an annular snap-fit ​​ring.

8. The single-point pulse ablation pressure catheter according to claim 7, wherein, The tube body has a connecting component at one end near the front electrode. The connecting component has a large-diameter end and a small-diameter end. The large-diameter end is sleeved on one end of the tube body, and the small-diameter end is sleeved inside the main structure and contacts the snap ring.

9. The single-point pulse ablation pressure catheter according to claim 8, wherein, A hollow structure is provided on the large-diameter end, and the first optical fiber extends into the tube body through the hollow structure.

10. A single-point pulse ablation device, wherein, Includes the single-point pulse ablation pressure catheter as described in any one of claims 1-9.

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