Self-stabilization type oil-water double-soluble transparent essence oil and preparation method thereof

Abstract

The invention relates to self-stabilization type oil-water double-soluble transparent essence oil and a preparation method thereof, and the essence oil comprises the following components by weight: 11-25% of macadamia nut seed oil, 1-3% of Candida bee / glucose / rapeseed methyl oleate fermentation product, 10-20% of plant extract composite liquid, and the balance of caprylic acid / capric triglyceride and 1, 2-hexanediol in a mass ratio of (0.9-1.2): 1. Wherein the plant extraction compound liquid is an aqueous solution of a plant extraction compound, and the plant extraction compound is a composition of a cockscomb extract, an andrographis paniculata leaf extract and a campsis grandiflora extract. The essence oil realizes a self-stabilization transparent system without a traditional emulsifier, can stably contain 10-20% of plant extraction composite liquid, has high-content water-soluble active matters, stable and transparent oil properties and good skin compatibility, also realizes repairing and anti-inflammatory effects, and avoids the problem of weak effect of single plant extraction.

Description

Technical Field

[0001] This invention relates to the technical field of cosmetics, specifically to a self-stabilizing, oil-water dual-soluble transparent essence oil and its preparation method. Background Technology

[0002] Traditional facial oils with soothing and anti-inflammatory properties on the market typically face three major technical challenges when dealing with the relationship between aqueous solutions containing plant extracts and oily bases: 1. Poor solubility leads to low utilization of active ingredients: Extracts from plants such as Andrographis paniculata and Celosia cristata are soluble in aqueous solutions, but they are difficult to dissolve in pure oils. Due to the lack of effective solubilization methods, traditional essential oils can usually only contain less than 5% aqueous phase. If too much aqueous phase is added, layering, turbidity, and precipitation are very likely to occur, making it impossible to maintain a transparent and homogeneous state. 10%-20% is the amount added at the serum level, which is extremely difficult to achieve in oil-based systems.

[0003] 2. Reliance on traditional emulsifiers, resulting in an oily feel and a tendency to cause acne: To add aqueous solutions containing plant extracts to oils, traditional products must add chemical emulsifiers to create a milky white lotion or microemulsion. However, emulsifiers themselves often create a sticky feeling, and combined with oils, this results in a strong film-forming effect and poor breathability after application. For oily skin that is already prone to acne, the high content of traditional emulsifiers and occlusive oils can easily clog pores. Moreover, over time, the lotion is prone to separation, emulsion breakdown, and the separation of water droplets.

[0004] 3. Limitations on the addition of plant extracts: If a single water-soluble plant extract is added, the concentration must be controlled at an extremely low level (usually below 5%), otherwise the stability of the system will be compromised. If multiple water-soluble plant extracts are combined, precipitation and turbidity are likely to occur, rendering the product unusable. Therefore, most existing products use single plant extracts, and the amount added is insufficient, failing to achieve synergistic effects of multiple ingredients. They can only exert a single effect, with weak results, making it difficult to meet the multi-dimensional repair needs of the skin.

[0005] Current essential oils struggle to simultaneously achieve the four effects of "high plant extract aqueous solution content", "refreshing and transparent oil texture", "gentle and non-irritating, which may aggravate sensitive skin", and "soothing, anti-oxidation and repair". Summary of the Invention

[0006] The purpose of this invention is to overcome the shortcomings of the prior art and provide a self-stabilizing, oil-water dual-soluble transparent essence oil and its preparation method.

[0007] To achieve the above objectives, the technical solution adopted by the present invention is as follows: In a first aspect, the present invention provides a self-stabilizing, oil-water dual-soluble transparent essence oil, comprising the following components in parts by weight: 11-25% macadamia seed oil, 1-3% fermentation product of Candida albicans / glucose / rapeseed oleate and 10-20% plant extract complex liquid, with the balance being caprylic / capric triglycerides and 1,2-hexanediol in a mass ratio of (0.9-1.2):1; wherein the plant extract complex liquid is an aqueous solution of the plant extract complex, and the plant extract complex is a composition of cockscomb flower extract, andrographis paniculata leaf extract and trumpet creeper flower extract.

[0008] 1,2-Hexanediol possesses both hydrophilic and lipophilic properties, reducing interfacial tension. Without the need for emulsifiers, it allows aqueous extracts to be uniformly dispersed in the oil phase, forming a transparent homogeneous system. This is key to achieving oil-water dual solubility, enabling a high proportion of 10-20% aqueous phase addition, far exceeding the traditional 5% upper limit of essential oils. It also provides a refreshing feel, accelerates penetration, has antibacterial properties, and reduces the need for preservatives.

[0009] Caprylic / capric triglycerides are light moisturizing oils and non-polar solvents that can dissolve fat-soluble components. They are chemically stable, not easily oxidized, and help maintain the long-term stability of essential oils.

[0010] The fermentation product of *Candida albicans* / glucose / methyl rapeseed oil is a biosurfactant, emulsifying stabilizer, and active ingredient. As an amphiphilic molecule, it can oriented at the oil-water interface, further reducing interfacial tension and preventing the aggregation and precipitation of trace amounts of water or extracts, ensuring long-term transparency and stability of the system. It can oriented to reduce interfacial tension and prevent precipitation. At the same time, it also has natural antibacterial, anti-inflammatory, and oil-controlling properties, which can help improve acne-prone and sensitive skin. Furthermore, being derived from bio-fermentation, it is gentler and more environmentally friendly than traditional chemical surfactants.

[0011] Macadamia seed oil is rich in palmitoleic acid, whose structure is very similar to the fatty acids in human sebum. Therefore, it has excellent affinity and permeability and can be quickly absorbed by the skin.

[0012] The specific functions of the plant extract complex are as follows: Andrographis paniculata leaf extract is rich in andrographolide, which has significant anti-inflammatory activity, inhibits the release of inflammatory factors (such as TNF-α and IL-6), and also has an inhibitory effect on Propionibacterium acnes.

[0013] Cockscomb flower extract is rich in cockscomb extract and flavonoids. On the one hand, it has a significant astringent effect, helping to tighten pores dilated by inflammation and control excessive oil secretion; on the other hand, it has excellent antioxidant and soothing abilities, relieving skin stinging and itching, and repairing damaged lipid films.

[0014] Trumpet creeper flower extract can inhibit the release of inflammatory factors and relieve sensitive symptoms such as itchy, red, and swollen skin.

[0015] Preferably, the mass concentration of the plant extract compound solution is 10-30 wt%.

[0016] Preferably, the mass ratio of the cockscomb flower extract, the andrographis paniculata leaf extract, and the trumpet creeper flower extract is (0.3-0.8):1:(1.5-3).

[0017] In a second aspect, the present invention provides a method for preparing the self-stabilizing, oil-water-soluble, transparent essence oil described in the first aspect, comprising the following steps: S1. Mix macadamia seed oil with fermentation products of Candida albicans / glucose / rapeseed oleate to obtain a premixed oil phase; S2. Stir and mix octanoic acid / capric acid triglyceride and 1,2-hexanediol to obtain an oil-alcohol solution; S3. Add the plant extract complex liquid to the oil-alcohol solution obtained in step S2, stir and mix to obtain a transparent microemulsion; S4. Stir and mix the premixed oil phase obtained in step S1 with the transparent microemulsion obtained in step S3, let it stand to defoam, filter, and obtain the self-stabilizing oil-water dual-soluble transparent essence oil.

[0018] Preferably, in step S3, the stirring temperature is 40-50℃, the stirring speed is 400-600 rpm, and the stirring time is 15-30 min.

[0019] Preferably, in step S4, a 0.22-0.45 μm microporous membrane is used for filtration.

[0020] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) In this technical solution, an oil-alcohol homogeneous phase is formed by caprylic / capric triglyceride and 1,2-hexanediol in a specific ratio. Through the solubilizing effect of 1,2-hexanediol, the water-soluble plant extract complex is uniformly dispersed in the oily system, thereby achieving a self-stabilizing and transparent system without the need for traditional emulsifiers. The system is mild and non-irritating. Moreover, this system has good compatibility with the plant extract complex, and can stably accommodate 10-20% of the plant extract complex. It can also achieve uniform dispersion of three water-soluble extracts: cockscomb flower extract, andrographis paniculata leaf extract, and trumpet creeper flower extract, without worrying about precipitation or turbidity. This advantage completely solves the defects of existing products, such as low plant extract content and inability to be compounded. This makes the essential oil of this invention have a high content of water-soluble active ingredients, a stable and transparent oily texture, and good skin compatibility. It allows the cockscomb flower extract, andrographis paniculata leaf extract, and trumpet creeper flower extract to fully exert their synergistic effect, achieving repair and anti-inflammatory effects, and avoiding the problem of weak efficacy of a single plant extract.

[0021] (2) Compared with the limitations of existing products that use only single plant extracts, the extracts of cockscomb, andrographis paniculata and trumpet creeper work synergistically from multiple targets such as anti-inflammatory, antioxidant, redness reduction and repair, which can solve complex problems such as skin sensitivity, acne and barrier damage at the same time. Attached Figure Description

[0022] Figure 1 This is a photograph of the transparent essential oil of the present invention. Detailed Implementation

[0023] To better illustrate the purpose, technical solution, and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0024] The raw materials used in the following examples and comparative examples are as follows: Macadamia seed oil: Manufacturer is OShiNatural, product name is South African Organic Macadamia Oil; Fermentation product of Candida albicans / glucose / methyl rapeseed oil: Manufacturer: SpecBio® SL-Active; Sophorolipid surfactant: Manufacturer: Evonik, Model: REWOFERM SL ONE; Cockscomb flower extract: Manufacturer: Shaanxi Sinote Biotechnology Co., Ltd.; Trade name: Cockscomb pollen; Product specification: 10:1. Andrographis paniculata leaf extract: manufactured by Shaanxi Sinote Biotechnology Co., Ltd., product specification 10:1; Trumpet creeper flower extract: Manufacturer: Shaanxi Xintianyu Biotechnology Co., Ltd., Product specification: 10:1; Unless otherwise specified, all other materials and reagents used in the examples are commercially available.

[0025] Example 1 A self-stabilizing, oil-water dual-soluble, transparent essence oil comprises the following components in parts by weight: 21% macadamia seed oil, 2% *Candida albicans* / glucose / rapeseed oleate fermentation product, and 14% plant extract complex liquid, with the balance being caprylic / capric triglycerides and 1,2-hexanediol in a mass ratio of 1.1:1; wherein the plant extract complex liquid is an aqueous solution of a plant extract complex with a mass concentration of 25 wt%, and the plant extract complex is a composition of cockscomb flower extract, andrographis paniculata leaf extract, and trumpet creeper flower extract in a mass ratio of 0.7:1:2.2; A method for preparing a self-stabilizing, oil-water dual-soluble, transparent essence oil includes the following steps: S1. Mix macadamia seed oil with fermentation products of Candida albicans / glucose / rapeseed oleate to obtain a premixed oil phase; S2. Stir and mix octanoic acid / capric acid triglyceride and 1,2-hexanediol to obtain an oil-alcohol solution; S3. Add the plant extract complex liquid to the oil-alcohol solution obtained in step S2, stir and mix to obtain a transparent microemulsion; wherein, the stirring temperature is 45℃, the stirring speed is 500rpm, and the stirring time is 20min; S4. Stir and mix the premixed oil phase obtained in step S1 with the transparent microemulsion obtained in step S3, let it stand to remove bubbles, and filter it with a 0.3μm microporous membrane to obtain the self-stabilizing oil-water dual-soluble transparent essence oil.

[0026] Example 2 A self-stabilizing, oil-water dual-soluble, transparent essence oil comprises the following components in parts by weight: 25% macadamia seed oil, 1-3% fermentation product of *Candida albicans* / glucose / rapeseed oleate, and 10% plant extract complex liquid, with the balance being caprylic / capric triglycerides and 1,2-hexanediol in a mass ratio of 1.2:1; wherein the plant extract complex liquid is an aqueous solution of a plant extract complex with a mass concentration of 30 wt%, and the plant extract complex is a composition of cockscomb flower extract, andrographis paniculata leaf extract, and trumpet creeper flower extract in a mass ratio of 0.3:1:1.5; A method for preparing a self-stabilizing, oil-water dual-soluble, transparent essence oil includes the following steps: S1. Mix macadamia seed oil with fermentation products of Candida albicans / glucose / rapeseed oleate to obtain a premixed oil phase; S2. Stir and mix octanoic acid / capric acid triglyceride and 1,2-hexanediol to obtain an oil-alcohol solution; S3. Add the plant extract complex liquid to the oil-alcohol solution obtained in step S2, stir and mix to obtain a transparent microemulsion; wherein, the stirring temperature is 40℃, the stirring speed is 400 rpm, and the stirring time is 30 min; S4. Stir and mix the premixed oil phase obtained in step S1 with the transparent microemulsion obtained in step S3, let it stand to remove bubbles, and filter it with a 0.22μm microporous membrane to obtain the self-stabilizing oil-water dual-soluble transparent essence oil.

[0027] Example 3 A self-stabilizing, oil-water dual-soluble, transparent essence oil comprises the following components in parts by weight: 11% macadamia seed oil, 3% *Candida beeinae* / glucose / rapeseed oleate methyl ester fermentation product, and 20% plant extract complex liquid, with the balance being caprylic / capric triglycerides and 1,2-hexanediol in a mass ratio of 0.9:1; wherein the plant extract complex liquid is an aqueous solution of a plant extract complex with a mass concentration of 10 wt%, and the plant extract complex is a composition of cockscomb flower extract, andrographis paniculata leaf extract, and trumpet creeper flower extract in a mass ratio of 0.8:1:3; A method for preparing a self-stabilizing, oil-water dual-soluble, transparent essence oil includes the following steps: S1. Mix macadamia seed oil with fermentation products of Candida albicans / glucose / rapeseed oleate to obtain a premixed oil phase; S2. Stir and mix octanoic acid / capric acid triglyceride and 1,2-hexanediol to obtain an oil-alcohol solution; S3. Add the plant extract complex liquid to the oil-alcohol solution obtained in step S2, stir and mix to obtain a transparent microemulsion; wherein, the stirring temperature is 50℃, the stirring speed is 600 rpm, and the stirring time is 15 min; S4. Stir and mix the premixed oil phase obtained in step S1 with the transparent microemulsion obtained in step S3, let it stand to remove bubbles, and filter it with a 0.45μm microporous membrane to obtain the self-stabilizing oil-water dual-soluble transparent essence oil.

[0028] Example 4 The only difference between Example 4 and Example 1 is that the amount of plant extract complex added remains the same, and the mass ratio of cockscomb flower extract, andrographis paniculata leaf extract and trumpet creeper flower extract is 1:0.7:2.2.

[0029] Example 5 The only difference between Example 5 and Example 1 is that the amount of plant extract complex added remains the same, and the mass ratio of cockscomb flower extract, andrographis paniculata leaf extract and trumpet creeper flower extract is 0.7:2.2:1.

[0030] Comparative Example 1 The only difference between Comparative Example 1 and Example 1 is that no plant extract complex was added, and the missing amount was made up with an equal amount of water.

[0031] Comparative Example 2 The only difference between Comparative Example 2 and Example 1 is that the amount of plant extract complex added remains the same, cockscomb extract is not added, and the missing amount is made up by Andrographis paniculata leaf extract and Campsis grandiflora flower extract in a mass ratio of 1:2.2.

[0032] Comparative Example 3 The only difference between Comparative Example 3 and Example 1 is that the amount of plant extract complex added remains the same, and Andrographis paniculata leaf extract is not added. Instead, cockscomb flower extract and trumpet creeper flower extract in a mass ratio of 0.7:2.2 are used to make up for the missing amount.

[0033] Comparative Example 4 The only difference between Comparative Example 4 and Example 1 is that the amount of plant extract complex added remains the same, the trumpet creeper extract is not added, and the missing amount is made up by cockscomb flower extract and andrographis paniculata leaf extract in a mass ratio of 0.7:1.

[0034] Comparative Example 5 The only difference between Comparative Example 5 and Example 1 is that the fermentation product of Candida albicans / glucose / methyl rapeseed oil was replaced with a sophorolipid surfactant.

[0035] Comparative Example 6 The only difference between Comparative Example 6 and Example 1 is that the amount of plant extract compound added is 21 wt%, and the excess is made up by caprylic / capric triglyceride and 1,2-hexanediol in a mass ratio of 1.1:1.

[0036] Test Example 1: Anti-inflammatory Properties Test of Essential Oils The essential oils prepared in Examples 1-5 and Comparative Examples 1-5 were used as test samples, and the specific test steps are as follows: (1) Inoculation: The cell line used was HaCaT cells. The cells were seeded into 24-well plates and cultured at 37°C with 5% CO2.

[0037] (2) LPS induction: After culturing for 24 hours, the culture medium in the plate was aspirated and washed once with PBS. The blank control group was added with DEME cell culture medium, while the negative control group and the sample group were added with an equal amount of DEME cell culture medium containing 1 μg / mL LPS. They were cultured at 37°C and 5% CO2 for 24 h. Each treatment group had 3 replicates.

[0038] (3) After induction, the culture medium was replaced: DEME cell culture medium was added to both the blank control group and the negative control group, and an equal amount of DEME cell culture medium containing 1 mg / mL of test sample was added to the sample group. The samples were cultured at 37°C and 5% CO2 for 24 h.

[0039] (4) Detection of inflammatory factor content: Take the cell supernatant from each well and detect the content of cellular inflammatory factors TNF-α and IL-6 according to the ELISA kit instructions, and calculate the inflammatory factor inhibition rate; the calculation formula is shown below: Inflammatory factor inhibition rate (%) = (average concentration of negative control group - average concentration of sample group) / average concentration of negative control group × 100%. See Table 1 for specific data. A higher inflammatory factor inhibition rate indicates a better anti-inflammatory effect of the essential oil.

[0040] Table 1. Inhibition rate of inflammatory factors in each group of essential oils Group / Performance TNF-α inhibition rate / % IL-6 inhibition rate / % Example 1 66.0 69.3 Example 2 65.3 68.1 Example 3 64.8 67.6 Example 4 60.1 63.8 Example 5 61.7 64.3 Comparative Example 1 29.1 30.6 Comparative Example 2 40.8 42.2 Comparative Example 3 36.7 38.5 Comparative Example 4 42.4 44.3 Comparative Example 5 38.1 40.1 As can be seen from the data in Examples 1 and 4-5 in Table 1, when the mass ratio of cockscomb extract, andrographis paniculata leaf extract and trumpet creeper extract in the plant extract complex is in the range of (0.3-0.8):1:(1.5-3), the anti-inflammatory effect of the essential oil is at a better level.

[0041] Based on the data from Example 1 and Comparative Examples 1-4, it can be seen that Comparative Example 1 had the worst anti-inflammatory performance among all groups. This indicates that the plant extract complex is an important parameter affecting the anti-inflammatory performance of the essential oil. The TNF-α inhibition rate and IL-6 inhibition rate of the essential oils in Comparative Examples 2-4 were significantly lower than those in Example 1. This indicates that the extracts of cockscomb flower, andrographis paniculata leaf, and trumpet creeper flower can synergistically improve the anti-inflammatory effect of the essential oil.

[0042] Based on the data from Example 1 and Comparative Example 5, it can be seen that the anti-inflammatory effect of the essential oil in Comparative Example 5 is lower than that in Example 1. This may be because the fermentation product of Candida albicans / glucose / methyl rapeseed oil has auxiliary anti-inflammatory and repairing effects. If it is replaced with sophorolipid surfactants that only play an emulsifying and solubilizing role and have no anti-inflammatory effect, the anti-inflammatory effect of the essential oil will be reduced.

[0043] Test Example 2: Stability Test of Essential Oils Take 20 mL each of the essential oils from Example 1 and Comparative Examples 1 and 5-6 and place them in glass bottles. Two samples are taken from each group. Before testing, the essential oils in each group are light yellow / light brown transparent and clear liquids, without any visible insoluble particles, and are uniform and do not separate into layers. Place each group of essential oils in a constant temperature and humidity chamber (48℃) for 1 month; for cold resistance, place them in a refrigerator at 0-2℃ for 1 month; and for room temperature for 3 months. After the tests, observe their appearance. Then, observe the condition of the essential oils after placing them at room temperature for 2 months, as detailed in Table 2.

[0044] Table 2. Stability Tests of Each Group of Essential Oils

[0045] Depend on Figure 1 It can be seen that after being placed at room temperature for 2 months, the two groups of essential oils in Example 1 still maintained a transparent and clear appearance, without layering, sedimentation, or turbidity, and the color did not change significantly.

[0046] Based on the stability data of Example 1 and Comparative Example 1 under different temperature conditions in Table 2, it can be seen that Comparative Example 1, due to the lack of the antioxidant synergistic effect of the plant extract complex, experienced slight oxidation of the essential oil at high and room temperatures, resulting in a darker color. However, the system did not exhibit separation and showed good stability. This indicates that the plant extract complex is well compatible with the self-stabilizing oil-alcohol system, reducing component leaching and oxidation.

[0047] Based on the stability data of Example 1 and Comparative Example 5 under different temperature conditions in Table 2, it can be seen that the stability of Comparative Example 5 at high temperature, low temperature and room temperature is significantly lower than that of Example 1. This may be because sophorolipid surfactants can only assist in emulsification and have no antioxidant or plant extract stabilizing effect. At high temperature and room temperature, a large amount of plant extract complex is oxidized and precipitated. At low temperature, the solubility of plant extract complex decreases and the compatibility of oil-alcohol system decreases. This indicates that the fermentation product of Candida albicans / glucose / rapeseed oil methyl ester can significantly improve the storage stability of essential oils at high temperature, low temperature and room temperature.

[0048] Based on the stability data of Example 1 and Comparative Example 6 under different temperature conditions in Table 2, it can be seen that the stability of Comparative Example 6 at high temperature, low temperature and room temperature is significantly lower than that of Example 1. This indicates that the amount of plant extract compound liquid added is 21wt%, which exceeds the optimal range (10-20wt%) and exceeds the tolerance range of the oil-alcohol self-stabilizing system, resulting in a decrease in the solubility of the plant extract compound and affecting the storage stability of the essential oil under different conditions.

[0049] Test Example 3: Human Efficacy Test of Essential Oils Recruitment criteria: Volunteers with mild acne on their face (such as ≤10 papules or pustules) and independent acne scars with a diameter ≥3mm.

[0050] Exclusion criteria: Individuals who have recently (within 1 month) used hormonal drugs, anti-acne drugs, or undergone facial cosmetic treatments; individuals who are allergic to the components of the test sample; pregnant or breastfeeding women.

[0051] Grouping and Number of Participants: Eligible volunteers will be randomly divided into 8 groups of 5 people each.

[0052] Test samples: essential oils prepared in Examples 1, 4-5 and Comparative Examples 1-5 (double-blind method numbering).

[0053] Directions for use: After cleansing in the morning and evening, volunteers should take 1mL of the sample and apply it evenly to the entire face, gently massaging until fully absorbed. Use continuously for 14 days.

[0054] The volunteers' facial skin condition was tested on days 0 and 14. On the day of their visit, volunteers washed their faces with water without applying any products and sat quietly for 20 minutes in an air-conditioned room with a temperature of 21±1℃ and humidity of 50±10%. The size of the acne area and the skin's α-value (α-value, representing the erythema in the dermis and indicating the state of skin inflammation) were measured using a VISA instrument. Tests were performed three times before and after the experiment, and the average values ​​were taken. The improvement rate was calculated using the following formula: Improvement rate of acne area size (%) = [(mean acne area size before use - mean acne area size after use) / mean acne area size before use] × 100%; The improvement rate of α-value (%) = [(mean value of α-value before use - mean value of α-value after use) / mean value of α-value before use] × 100%. See Table 3 for specific data. The greater the improvement rate in acne area size, the better the acne-removing effect of the essential oil; the greater the improvement rate of α-value, the better the soothing and redness-reducing effect of the essential oil.

[0055] Table 3. Results of Human Efficacy Tests for Each Group of Essential Oils Group / Performance Acne area improvement rate / % a-value improvement rate / % Example 1 76.4 58.5 Example 4 70.8 53.6 Example 5 71.0 54.1 Comparative Example 1 34.3 26.3 Comparative Example 2 47.1 36.5 Comparative Example 3 42.7 32.9 Comparative Example 4 49.4 37.6 Comparative Example 5 44.3 34.0 As shown in Table 3, the acne-removing and soothing effects of the essential oils in Examples 1, 4-5 and Comparative Examples 2-5 were all improved compared with those in Comparative Example 1 (without the addition of plant extract complex).

[0056] Based on the data from Examples 1 and 4-5, it can be seen that when the mass ratio of cockscomb extract, andrographis paniculata leaf extract and trumpet creeper extract in the plant extract complex is in the range of (0.3-0.8):1:(1.5-3), the acne-removing and soothing effects of the essential oil are at a relatively good level.

[0057] Based on the data from Example 1 and Comparative Examples 2-4, it can be seen that the improvement rate of acne area and the improvement rate of a value of the essential oils in Comparative Examples 2-4 are significantly lower than those in Example 1. This indicates that the extracts of cockscomb flower, andrographis paniculata leaf, and trumpet creeper flower can synergistically improve the acne-removing and soothing effects of the essential oil.

[0058] Based on the data from Example 1 and Comparative Example 5, it can be seen that the acne-removing and soothing effects of the essential oil in Comparative Example 5 are lower than those in Example 1. This may be because the fermentation product of Candida albicans / glucose / methyl rapeseed oil has auxiliary anti-inflammatory and repairing effects. If it is replaced with sophorolipid surfactants that only play an emulsifying and solubilizing role and have no anti-inflammatory effect, the acne-removing and soothing effects of the essential oil will be reduced.

[0059] In summary, the essential oil of this invention possesses a self-stabilizing and transparent system that does not require traditional emulsifiers. This system exhibits excellent compatibility with plant extract complexes, stably accommodating 10-20% of the complex, and achieving uniform dispersion of the three water-soluble extracts: cockscomb flower extract, andrographis paniculata leaf extract, and trumpet creeper flower extract, without concerns about precipitation or turbidity. This advantage completely solves the shortcomings of existing products, such as low plant extract content and inability to be compounded, allowing the three extracts to fully exert their synergistic effects, achieving repair and anti-inflammatory efficacy, and simultaneously addressing complex issues such as skin sensitivity, acne, and damaged skin barrier.

[0060] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. A self-stabilizing, oil-water dual-solubility transparent essence oil, characterized in that: The product comprises the following components in parts by weight: 11-25% macadamia seed oil, 1-3% fermentation product of Candida albicans / glucose / rapeseed oil methyl ester, and 10-20% plant extract complex liquid, with the balance being caprylic / capric triglycerides and 1,2-hexanediol in a mass ratio of (0.9-1.2):1; wherein the plant extract complex liquid is an aqueous solution of the plant extract complex, and the plant extract complex is a combination of cockscomb flower extract, andrographis paniculata leaf extract, and trumpet creeper flower extract.

2. The self-stabilizing, oil-water dual-solubility transparent essence oil as described in claim 1, characterized in that, The mass concentration of the plant extract compound solution is 10-30 wt%.

3. The self-stabilizing, water-soluble, transparent essence oil as described in claim 1, characterized in that... The mass ratio of the cockscomb flower extract, andrographis paniculata leaf extract and trumpet creeper flower extract is (0.3-0.8):1:(1.5-3).

4. The method for preparing a self-stabilizing, oil-water dual-soluble transparent essence oil according to any one of claims 1-3, characterized in that, Includes the following steps: S1. Mix macadamia seed oil with fermentation products of Candida albicans / glucose / rapeseed oleate to obtain a premixed oil phase; S2. Stir and mix octanoic acid / capric acid triglyceride and 1,2-hexanediol to obtain an oil-alcohol solution; S3. Add the plant extract complex liquid to the oil-alcohol solution obtained in step S2, stir and mix to obtain a transparent microemulsion; S4. Stir and mix the premixed oil phase obtained in step S1 with the transparent microemulsion obtained in step S3, let it stand to defoam, filter, and obtain the self-stabilizing oil-water dual-soluble transparent essence oil.

5. The method for preparing a self-stabilizing, oil-water dual-soluble transparent essence oil as described in claim 1, characterized in that, In step S3, the stirring temperature is 40-50℃, the stirring speed is 400-600 rpm, and the stirring time is 15-30 min.

6. The method for preparing a self-stabilizing, oil-water dual-soluble transparent essence oil as described in claim 1, characterized in that, In step S4, filtration is performed using a 0.22-0.45 μm microporous membrane.

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