Sample analyzer

Abstract

The invention is applicable to the field of in-vitro diagnostic equipment, and discloses a sample analyzer. The sample analyzer comprises a sample determination assembly and a controller, the controller is configured to control the sample measuring assembly to execute a first sub-calibration process of a first item on the first calibrator through the first detection parameter to obtain a first optical measurement result; controlling the sample determination assembly to execute a second sub-calibration process of the first item on a second calibration product through the first detection parameter and the second detection parameter to obtain a second optical measurement result and a third optical measurement result; controlling the sample determination assembly to execute a third sub-calibration process of the first item on a third calibration product through a second detection parameter to obtain a fourth optical measurement result; and obtaining first calibration data of the first item according to the concentration of the target object in the first calibration product, the first optical measurement result, the concentration of the target object in the second calibration product, the second optical measurement result, the third optical measurement result, the concentration of the target object in the third calibration product and the fourth optical measurement result.

Description

Technical Field

[0001] This invention relates to the field of in vitro diagnostic equipment, and more particularly to a sample analyzer. Background Technology

[0002] Traditional sample analyzers typically use a single detection parameter (such as a single optical sensor and a single fixed detection wavelength) to measure each item. However, because the range of target analyte concentrations that can be measured using a single detection parameter is limited, the accuracy of the sample test results decreases when the target analyte concentration exceeds the range that can be measured using that single detection parameter.

[0003] To address the problems of traditional technologies, related technologies propose a scheme that uses different detection parameters (such as different photometric components and different wavelengths) to measure samples with different concentration ranges within a single sample analyzer. During calibration, this scheme requires different detection parameters to be used with calibrators to obtain different calibration curves. However, in practical applications, this technology still has the following shortcomings: because different detection parameters are performed using two sets of calibrators, and many of the calibrators in the two sets are different from each other, the sample analyzer suffers from a large number of calibrators, high calibrator consumption, and long calibration time. Summary of the Invention

[0004] The first objective of this invention is to provide a sample analyzer that addresses the technical problem of a large number of calibrators in sample analyzers of the related art.

[0005] To achieve the above objectives, the present invention provides a sample analyzer, comprising:

[0006] A sample measurement assembly, the sample measurement assembly being used to perform a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte being known; and to perform a sample measurement procedure for a sample used to detect the target analyte;

[0007] The controller is configured to perform the following calibration procedure for the first item:

[0008] The sample measurement component is controlled to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters to obtain the first photometric result;

[0009] The sample measurement component is controlled to perform the second sub-calibration process of the first item at least once on the second calibrator through the first detection parameter and the second detection parameter to obtain the second optical measurement result and the third optical measurement result. Each time the second sub-calibration process of the first item is performed by the sample measurement component on the same second calibrator through the first detection parameter and the second detection parameter.

[0010] The sample measurement component is controlled to perform the third sub-calibration process of the first item at least once on the third calibrator using the second detection parameters to obtain the fourth photometric result;

[0011] The first calibration data for the first item is obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result.

[0012] The controller is further configured to: control the sample measurement component to perform the sample measurement process of the first item on the same sample used to detect the target analyte using the first detection parameter and the second detection parameter, to obtain the sample photometric result, and to obtain the detection result of the concentration of the target analyte in the sample based on the sample photometric result and the first calibration data;

[0013] Wherein, the concentration of the target analyte in the second calibrator is greater than the concentration of the target analyte in the first calibrator, but less than the concentration of the target analyte in the third calibrator;

[0014] The first detection parameter and the second detection parameter are different detection parameters.

[0015] As one implementation, controlling the sample measurement component to perform at least one first sub-calibration process of the first item on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item on the first calibrator for the first time through the first detection parameter to obtain the first photometric result;

[0016] The method of controlling the sample measurement component to perform at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter to obtain a second optical measurement result and a third optical measurement result includes: controlling the sample measurement component to perform a second number of the second sub-calibration processes of the first item on the second calibrator using the first detection parameter and the second detection parameter to obtain a second optical measurement result and the third optical measurement result, wherein in each of the second sub-calibration processes of the first item in the second number of the first item, the second sub-calibration process of the first item is performed by the sample measurement component on the same second calibrator using the first detection parameter and the second detection parameter.

[0017] The method of controlling the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item a third time on the third calibrator through the second detection parameter to obtain the fourth photometric result;

[0018] Wherein, the second number is greater than or equal to the first number, and greater than or equal to the third number, and less than the sum of the first number and the third number.

[0019] In one implementation, the first number, the second number, and the third number are all greater than or equal to two;

[0020] And / or, the first number is equal to the third number.

[0021] In one implementation, controlling the sample measurement component to perform the first sub-calibration process of the first item for the first number of times on the first calibrator through the first detection parameters to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item for the first number of times on the first calibrator of the same concentration through the first detection parameters to obtain a first initial photometric value equal to the first number of times, and averaging the first initial photometric value equal to the first number of times to obtain the first photometric result of the first calibrator of that concentration;

[0022] The method of controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator using the first detection parameter and the second detection parameter to obtain the second photometric result and the third photometric result includes: controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator of the same concentration using the first detection parameter and the second detection parameter to obtain a second initial photometric value and a third initial photometric value equal to the second number of times; averaging the second initial photometric value equal to the second number of times to obtain the second photometric result of the second calibrator of that concentration; and averaging the third initial photometric value equal to the second number of times to obtain the third photometric result of the second calibrator of that concentration.

[0023] The method of controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator of the same concentration through the second detection parameter to obtain a fourth initial photometric value equal to the third number of times; averaging the fourth initial photometric value equal to the third number of times to obtain the fourth photometric result of the third calibrator of that concentration;

[0024] Alternatively, the first number, the second number, and the third number are all odd numbers greater than or equal to three. The step of controlling the sample measurement component to perform the first sub-calibration process of the first item of the first number of times on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item of the first number of times on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value with a quantity equal to the first number of times, and taking the first initial photometric value with the middle value among the first initial photometric values ​​with a quantity equal to the first number of times as the first photometric result of the first calibrator of that concentration;

[0025] The method of controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator using the first detection parameter and the second detection parameter to obtain the second photometric result and the third photometric result includes: controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator of the same concentration using the first detection parameter and the second detection parameter to obtain a second initial photometric value equal to the second number of times and a third initial photometric value equal to the second number of times; taking the second initial photometric value with the middle value among the second initial photometric values ​​equal to the second number of times as the second photometric result of the second calibrator of that concentration; and taking the third initial photometric value with the middle value among the third initial photometric values ​​equal to the second number of times as the third photometric result of the second calibrator of that concentration.

[0026] The method of controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator of the same concentration through the second detection parameter to obtain a fourth initial photometric value equal to the third number of times; and taking the fourth initial photometric value, which is the middle value among the fourth initial photometric values ​​equal to the third number of times, as the fourth photometric result of the third calibrator of that concentration.

[0027] Alternatively, if the first number, the second number, and the third number are all greater than or equal to four, the step of controlling the sample measurement component to perform the first sub-calibration process of the first item of the first number of times on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item of the first number of times on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value equal to the first number of times; averaging the remaining first initial photometric values ​​(excluding the maximum and minimum values) among the first initial photometric values ​​equal to the first number of times to obtain the first photometric result of the first calibrator of that concentration.

[0028] The method of controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator using the first detection parameter and the second detection parameter to obtain the second photometric result and the third photometric result includes: controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator of the same concentration using the first detection parameter and the second detection parameter to obtain a second initial photometric value equal to the second number of times and a third initial photometric value equal to the second number of times; averaging the remaining second initial photometric values ​​(excluding the maximum and minimum values) among the remaining second initial photometric values ​​(excluding the maximum and minimum values) to obtain the second photometric result of the second calibrator of that concentration; and averaging the remaining third initial photometric values ​​(excluding the maximum and minimum values) among the remaining third initial photometric values ​​(excluding the maximum and minimum values) to obtain the third photometric result of the second calibrator of that concentration.

[0029] The method of controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator of the same concentration through the second detection parameter to obtain a fourth initial photometric value equal to the third number of times; averaging the remaining fourth initial photometric values ​​(excluding the maximum and minimum values) among the fourth initial photometric values ​​equal to the third number of times to obtain the fourth photometric result of the third calibrator of that concentration.

[0030] As one implementation, controlling the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item for at least two first calibrators with different concentrations for the first time through the first detection parameter to obtain at least two first photometric results that correspond one-to-one with the at least two first calibrators.

[0031] The method of controlling the sample measurement component to perform the second sub-calibration process of the first item at least once on the second calibrator through the first detection parameter and the second detection parameter to obtain the second photometric result and the third photometric result includes: controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on at least one second calibrator to obtain at least one second photometric result corresponding to the at least one second calibrator and at least one third photometric result corresponding to the at least one second calibrator;

[0032] The method of controlling the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item a third time on at least two third calibrators with different concentrations respectively through the second detection parameter to obtain at least two fourth photometric results that correspond one-to-one with the at least two third calibrators;

[0033] The step of obtaining first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result includes: obtaining the first calibration data based on the concentration of the target analyte in at least two first calibrators and the at least two first photometric results, the concentration of the target analyte in at least one second calibrator and the at least one second photometric result and the at least one third photometric result, and the concentration of the target analyte in at least two third calibrators and the at least two fourth photometric results.

[0034] In one implementation, controlling the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the sample measurement component to measure the second calibrator allocated to a reaction vessel using the first detection parameter to obtain a second initial photometric value; controlling the sample measurement component to measure the second calibrator in the reaction vessel using the second detection parameter or controlling the sample measurement component to measure the second calibrator transferred from the reaction vessel to another reaction vessel using the second detection parameter to obtain a third initial photometric value;

[0035] Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once;

[0036] The process of obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once.

[0037] In one embodiment, the sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component is used to add the calibrator into the reaction container, the reagent dispensing component is used to add the reagent into the reaction container, and the optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is at least composed of the calibrator and the reagent.

[0038] The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

[0039] In one implementation, when the different detection parameters include reagents with different components and / or different concentrations, the control of the sample measurement component to perform a first sub-calibration process of the first item on the first calibrator at least once using the first detection parameters includes: performing at least once the following process: controlling the reagent dispensing component to add the first reagent into the first reaction container; controlling the sample dispensing component to add the first calibrator into the first reaction container; controlling the photometric component to perform optical measurement on the first reaction solution in the first reaction container, which is at least made of the first calibrator and the first reagent, to obtain the first initial photometric value;

[0040] The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once;

[0041] The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the reagent dispensing component to add the first reagent into the second reaction container; controlling the sample dispensing component to add the second calibrator into the second reaction container; controlling the photometric component to perform optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain the second initial photometric value; controlling the reagent dispensing component to add the second reagent into the second reaction container or controlling the reagent dispensing component to add the second reagent into a third reaction container independent of the second reaction container; controlling the photometric component to perform optical measurement on the third reaction liquid in the second reaction container, which is at least composed of the second reagent and the second reaction liquid, or controlling the photometric component to perform optical measurement on the third reaction liquid in the third reaction container, which is at least composed of the second reagent and the second reaction liquid transferred from the second reaction container to the third reaction container, to obtain the third initial photometric value;

[0042] Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once;

[0043] The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once;

[0044] The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator using the second detection parameter includes: performing the following process at least once: controlling the reagent dispensing component to add the first reagent into the fourth reaction container; controlling the sample dispensing component to add the third calibrator into the fourth reaction container; controlling the reagent dispensing component to add the second reagent into the fourth reaction container; controlling the photometric component to perform optical measurement on the fourth reaction solution in the fourth reaction container, which is at least made of the third calibrator, the first reagent, and the second reagent, to obtain the fourth initial photometric value;

[0045] The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once;

[0046] The first reagent and the second reagent differ in at least one of the following aspects: composition and concentration;

[0047] Alternatively, when the different detection parameters include different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component;

[0048] The control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter includes: performing the following process at least once: controlling the first photometric component to perform optical measurement on the reaction liquid in the first reaction container made of at least the first calibrator and reagent to obtain the first initial photometric value;

[0049] The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once;

[0050] The control of the sample measurement component to perform at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter to obtain a second optical measurement result and a third optical measurement result includes: performing at least one of the following processes: controlling the first optical measurement component to perform optical measurement on the reaction liquid in the second reaction container, which is made of at least the second calibrator and the reagent, to obtain a second initial optical measurement value; controlling the second optical measurement component to perform optical measurement on the reaction liquid in the second reaction container, which is made of at least the second calibrator and the reagent, or controlling the second optical measurement component to perform optical measurement on the reaction liquid in a third reaction container, which is independent of the second reaction container, which is made of at least the reagent and the second calibrator transferred from the second reaction container to the third reaction container, to obtain the third initial optical measurement value;

[0051] Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once;

[0052] The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once;

[0053] The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter includes: performing the following process at least once: controlling the second photometric component to perform optical measurement on the reaction liquid in the fourth reaction vessel made of at least the third calibrator and reagents to obtain the fourth initial photometric value;

[0054] The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once;

[0055] Among them, one of the first optical measurement component and the second optical measurement component is a transmission light detector, and the other is a scattering light detector;

[0056] Alternatively, when the different detection parameters include different components and / or different concentrations of reagents and different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component;

[0057] The control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter includes: performing the following process at least once: controlling the reagent dispensing component to add the first reagent into the first reaction container; controlling the sample dispensing component to add the first calibrator into the first reaction container; controlling the first photometric component to perform optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and the first reagent, to obtain the first initial photometric value;

[0058] The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once;

[0059] The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the reagent dispensing component to add the first reagent into the second reaction container; controlling the sample dispensing component to add the second calibrator into the second reaction container; controlling the first photometric component to perform optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain the second initial photometric value; controlling the reagent dispensing component to add the second reagent into the second reaction container or controlling the reagent dispensing component to add the second reagent into a third reaction container independent of the second reaction container; controlling the second photometric component to perform optical measurement on the third reaction liquid in the second reaction container, which is at least composed of the second reagent and the second reaction liquid, or controlling the second photometric component to perform optical measurement on the third reaction liquid in the third reaction container, which is at least composed of the second reagent and the second reaction liquid transferred from the second reaction container to the third reaction container, to obtain the third initial photometric value;

[0060] Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once;

[0061] The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once;

[0062] The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator using the second detection parameter includes: performing the following process at least once: controlling the reagent dispensing component to add the first reagent into the fourth reaction container; controlling the sample dispensing component to add the third calibrator into the fourth reaction container; controlling the reagent dispensing component to add the second reagent into the fourth reaction container; controlling the second photometric component to perform optical measurement on the fourth reaction solution in the fourth reaction container, which is at least made of the third calibrator, the first reagent, and the second reagent, to obtain the fourth initial photometric value;

[0063] The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once;

[0064] The first reagent and the second reagent differ in at least one of the following aspects: composition and concentration;

[0065] One of the first optical measurement component and the second optical measurement component is a transmitted light detector, and the other is a scattered light detector;

[0066] Alternatively, when the different detection parameters include light of different wavelengths, the control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters includes: performing the following process at least once: controlling the photometric component to perform optical measurement of light of the first wavelength on the reaction liquid in the first reaction vessel made of at least the first calibrator and reagents to obtain the first initial photometric value;

[0067] The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once;

[0068] The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the photometric component to perform optical measurement of light of the first wavelength on the reaction liquid in the second reaction container, which is made of at least the second calibrator and the reagent, to obtain the second initial photometric value; controlling the photometric component to perform optical measurement of light of the second wavelength on the reaction liquid in the second reaction container, which is made of at least the second calibrator and the reagent, or controlling the photometric component to perform optical measurement of light of the second wavelength on the reaction liquid in the third reaction container, which is independent of the second reaction container, which is made of at least the reagent and the second calibrator transferred from the second reaction container to the third reaction container, to obtain the third initial photometric value;

[0069] Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once;

[0070] The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once;

[0071] The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter includes: performing the following process at least once: controlling the photometric component to perform optical measurement of the second wavelength of light on the reaction liquid made of at least the third calibrator and reagent in the fourth reaction vessel to obtain the fourth initial photometric value;

[0072] The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once;

[0073] Wherein, the second wavelength is greater than or less than the first wavelength;

[0074] Alternatively, when the different detection parameters include different reaction times, the control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters includes: performing the following process at least once: controlling the photometric component to perform optical measurement on the reaction liquid in the first reaction container prepared by at least the first calibrator and reagent under the first reaction time to obtain the first initial photometric value;

[0075] The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once;

[0076] The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the photometric component to perform optical measurement on the reaction solution prepared in the second reaction container by at least the second calibrator and reagent under the first reaction time to obtain the second initial photometric value; controlling the photometric component to perform optical measurement on the reaction solution prepared in the second reaction container by at least the second calibrator and reagent under the second reaction time to obtain the third initial photometric value;

[0077] Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once;

[0078] The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once;

[0079] The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter includes: performing the following process at least once: controlling the photometric component to perform optical measurement on the reaction liquid prepared in the fourth reaction vessel by at least the third calibrator and reagent under the second reaction time to obtain the fourth initial photometric value;

[0080] The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once;

[0081] Wherein, the second reaction time is greater than or less than the first reaction time;

[0082] Alternatively, when the different detection parameters include different blank durations, the control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters includes: performing the following process at least once: controlling the photometric component to perform optical measurement on the reaction solution in the first reaction vessel prepared by at least the first calibrator and reagent under the first blank duration to obtain the first initial photometric value;

[0083] The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once;

[0084] The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the photometric component to perform optical measurement on the reaction solution prepared in the second reaction container by at least the second calibrator and reagent under the first blank time to obtain the second initial photometric value; controlling the photometric component to perform optical measurement on the reaction solution prepared in the second reaction container by at least the second calibrator and reagent under the second blank time to obtain the third initial photometric value;

[0085] Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once;

[0086] The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once;

[0087] The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter includes: performing the following process at least once: controlling the photometric component to perform optical measurement on the reaction solution prepared in the fourth reaction vessel by at least the third calibrator and reagent under the second blank time to obtain the fourth initial photometric value;

[0088] The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once;

[0089] Wherein, the second blank duration is greater than or less than the first blank duration.

[0090] In one embodiment, the sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component includes a sample needle for adding the calibrator into the reaction container. The reagent dispensing component is used to add reagents into the reaction container. The optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least the calibrator and the reagent.

[0091] The method of controlling the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample needle to distribute the first calibrator of the same concentration into a first number of reaction containers, controlling the photometric component to perform optical measurement on the reaction solution made of at least the first calibrator and the reagent in the first number of reaction containers to obtain the first number of first initial photometric values, and obtaining the first photometric result based on the first number of first initial photometric values;

[0092] The method of controlling the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter to obtain a second photometric result and a third photometric result includes: controlling the sample needle to distribute the second calibrator of the same concentration into a second number of reaction containers; controlling the photometric component to perform optical measurements on the reaction solution made of at least the second calibrator and the reagent in the second number of reaction containers to obtain a second number of second initial photometric values ​​and a third number of third initial photometric values; obtaining a second photometric result based on the second number of second initial photometric values; obtaining a third photometric result based on the second number of third initial photometric values; and obtaining a second initial photometric value and a third initial photometric value by performing optical measurements on the reaction solution made of at least the second calibrator and the reagent in each of the second number of reaction containers.

[0093] The method of controlling the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample needle to distribute the third calibrator of the same concentration into the third number of reaction containers respectively; controlling the photometric component to perform optical measurement on the reaction solution made of at least the third calibrator and the reagent in the third number of reaction containers respectively to obtain the third number of fourth initial photometric values; and obtaining the fourth photometric result based on the third number of fourth initial photometric values.

[0094] Wherein, the second quantity is greater than or equal to the first quantity, and greater than or equal to the third quantity, and less than the sum of the first quantity and the third quantity.

[0095] In one implementation, the sample analyzer further includes a display, which is at least used to display the calibration results interface of the first item;

[0096] After obtaining the first calibration data, the controller is further configured to control the display to display the first calibration data in the calibration result interface of its first item.

[0097] In one implementation, the first calibration data is a continuous first calibration curve, and controlling the display to display the first calibration data in the calibration result interface of its first item includes: controlling the display to display the continuous first calibration curve in the calibration result interface of its first item;

[0098] Alternatively, the first calibration data includes a second calibration curve and a third calibration curve, which are spaced apart from each other. Obtaining the first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result includes: obtaining the second calibration curve based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result.

[0099] The third calibration curve is obtained based on the concentration of the target analyte in the second calibrator and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result;

[0100] Controlling the display to display the first calibration data in the calibration result interface of its first item includes: controlling the display to display the second calibration curve and the third calibration curve in the calibration result interface of its first item.

[0101] In one implementation, the sample analyzer further includes a display, which is at least used to display the calibration result details interface for each of the calibrators used in the first project, wherein the calibration result details interface for each of the calibrators displays the number of times the sub-calibration process is repeated for that calibrator and the photometric results;

[0102] The controller is also configured to:

[0103] In response to a first trigger command, the display is controlled to show the calibration result details interface of the first calibrator. The calibration result details interface of the first calibrator shows the number of times the first sub-calibration process is repeated and the first photometric result.

[0104] In response to the second trigger command, the display is controlled to show the calibration result details interface of the second calibrator. The calibration result details interface of the second calibrator shows the number of times the second calibrator repeats the second sub-calibration process, the second photometric result, and the third photometric result.

[0105] In response to a third trigger command, the display is controlled to show the calibration result details interface of the third calibrator. The calibration result details interface of the third calibrator shows the number of times the third calibrator repeats the third sub-calibration process and the fourth photometric result.

[0106] In one implementation, the display is also used to display a calibration result interface for the first item, which at least displays the first calibration data and information for each of the calibrators used in the sub-calibration process of the first item.

[0107] The first triggering instruction includes: an instruction formed by an operator viewing the first calibrator in the calibration result interface of the first item through at least one of screen touch, mouse operation, keyboard operation, and voice input;

[0108] The second triggering instruction includes: an instruction formed by the operator viewing the second calibrator in the calibration result interface of the first item through at least one of screen touch, mouse operation, keyboard operation, and voice input;

[0109] The third trigger command includes: a command generated by an operator viewing the third calibrator in the calibration result interface of the first item through at least one of screen touch, mouse control, keyboard control, and voice input.

[0110] In one implementation, the control of the sample measurement component to perform the first item sample measurement procedure on the same sample used to detect the target analyte using the first detection parameter and the second detection parameter, to obtain sample photometric results, and based on the sample photometric results and the first calibration data, to obtain the detection result of the concentration of the target analyte in the sample, including:

[0111] The sample measurement component is controlled to perform the first item sample measurement process on the same sample used to detect the target object through the first detection parameter and the second detection parameter, so as to obtain the fifth optical measurement result corresponding to the first detection parameter and the sixth optical measurement result corresponding to the second detection parameter;

[0112] Based on the fifth photometric result and the first calibration data, the first measurement data is obtained;

[0113] Based on the sixth photometric result and the first calibration data, the second measurement data is obtained;

[0114] Based on the first measurement data and the second measurement data, the detection results of the concentration of the target analyte in the sample are obtained.

[0115] In one implementation, the first calibration data includes a second calibration curve, a third calibration curve, and a fourth calibration curve;

[0116] The controller is also configured to execute the following calibration procedure for the first item: control the sample measurement component to perform the fourth sub-calibration procedure of the first item for the fourth time on the fourth calibrator to obtain the seventh and eighth photometric results; control the sample measurement component to perform the fifth sub-calibration procedure of the first item for the fifth time on the fifth calibrator to obtain the ninth photometric result;

[0117] The first calibration data for the first item is obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result, including:

[0118] The second calibration curve is obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result.

[0119] The third calibration curve is obtained based on the concentration of the target analyte in the second calibrator and the third photometric result, the concentration of the target analyte in the third calibrator and the fourth photometric result, and the concentration of the target analyte in the fourth calibrator and the seventh photometric result;

[0120] The fourth calibration curve is obtained based on the concentration of the target analyte in the fourth calibrator and the eighth photometric result, the concentration of the target analyte in the fifth calibrator and the ninth photometric result;

[0121] Wherein, the concentration of the target analyte in the fourth calibrator is greater than the concentration of the target analyte in the third calibrator;

[0122] The second calibration curve, the third calibration curve, and the fourth calibration curve are connected to form a continuous calibration curve, or at least two of the second calibration curve, the third calibration curve, and the fourth calibration curve are spaced apart from each other.

[0123] A second objective of the present invention is to provide a sample analyzer comprising:

[0124] A sample measurement assembly, the sample measurement assembly being used to perform a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte being known; and to perform a sample measurement procedure for a sample used to detect the target analyte;

[0125] The display is at least used to display the calibration result details interface for each of the calibrators used in the first project, wherein the calibration result details interface for each of the calibrators displays the number of times the sub-calibration process is repeated for that calibrator and the photometric results;

[0126] The controller is configured to:

[0127] In response to a first trigger command, the display is controlled to show the calibration result details interface of the first calibrator used in the first item. The calibration result details interface of the first calibrator shows the first number of times the sample measurement component repeatedly performs the sub-calibration process of the first item on the first calibrator using the first detection parameter and the first photometric result obtained by the sample measurement component performing the sub-calibration process of the first item on the first calibrator using the first detection parameter the first number of times.

[0128] In response to the second trigger command, the display is controlled to show the calibration result details interface of the second calibrator. The calibration result details interface of the second calibrator shows the second number of times the sample measurement component repeatedly performs the sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter, as well as the second and third photometric results obtained by the sample measurement component performing the sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter for the second number of times.

[0129] In response to a third trigger command, the display is controlled to show the calibration result details interface of the third calibrator. The calibration result details interface of the third calibrator shows the third number of times the sample measurement component repeatedly performs the sub-calibration process of the first item on the third calibrator using the second detection parameter, and the fourth photometric result obtained by the sample measurement component performing the sub-calibration process of the first item on the third calibrator using the second detection parameter.

[0130] Wherein, the concentration of the target analyte in the second calibrator is greater than the concentration of the target analyte in the first calibrator, but less than the concentration of the target analyte in the third calibrator;

[0131] The first detection parameter and the second detection parameter are different detection parameters.

[0132] In one implementation, the second number is greater than or equal to the first number, and greater than or equal to the third number, and less than the sum of the first number and the third number.

[0133] In one implementation, the first number, the second number, and the third number are all greater than or equal to two;

[0134] And / or, the first number is equal to the third number.

[0135] In one embodiment, the sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component is used to add the calibrator into the reaction container, the reagent dispensing component is used to add the reagent into the reaction container, and the optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is at least composed of the calibrator and the reagent.

[0136] The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

[0137] In one implementation, the controller is further configured to:

[0138] Based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result, a second calibration curve for the first item is obtained;

[0139] Based on the concentration of the target analyte in the second calibrator and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result, a third calibration curve for the first item is obtained;

[0140] The second calibration curve and the third calibration curve are connected to form a continuous first calibration curve; or the second calibration curve and the third calibration curve are set at intervals.

[0141] A third objective of this invention is to provide a sample analyzer comprising:

[0142] A sample measurement assembly, the sample measurement assembly being used to perform a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte being known; and to perform a sample measurement procedure for a sample used to detect the target analyte;

[0143] A controller, configured to control the operation of the sample measurement component;

[0144] The sample measurement component includes a sample dispensing component and an optical measurement component. The sample dispensing component includes a sample needle for adding the calibrator into the reaction container. The optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least the calibrator and the reagent.

[0145] The controller is configured to perform the following calibration procedure for the first item:

[0146] The sample needle is controlled to dispense the first calibrator of the same concentration into a first number of reaction containers, and the photometric component is controlled to perform optical measurements on the reaction solution made of at least the first calibrator and the reagent in the first number of reaction containers to obtain a first photometric result;

[0147] The sample needle is controlled to dispense the second calibrator of the same concentration into the second number of reaction containers, and the photometric component is controlled to perform optical measurements on the reaction solution in the second number of reaction containers, which is made of at least the second calibrator and the reagent, to obtain a second photometric result and a third photometric result.

[0148] The sample needle is controlled to dispense the same concentration of the third calibrator into the third number of reaction containers, and the photometric component is controlled to perform optical measurements on the reaction solution in the third number of reaction containers, which is made of at least the third calibrator and the reagent, to obtain a fourth photometric result.

[0149] First calibration data is obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result;

[0150] The controller is further configured to: control the sample measurement component to perform the sample measurement procedure of the first item on the same sample used to detect the target analyte, obtain sample photometric results, and obtain the detection result of the concentration of the target analyte in the sample based on the sample photometric results and the first calibration data;

[0151] Wherein, the concentration of the target analyte in the second calibrator is greater than the concentration of the target analyte in the first calibrator, but less than the concentration of the target analyte in the third calibrator;

[0152] The second quantity is greater than or equal to the first quantity, and greater than or equal to the third quantity, and less than the sum of the first quantity and the third quantity.

[0153] In one implementation, the first quantity, the second quantity, and the third quantity are all greater than or equal to two;

[0154] And / or, the first quantity is equal to the third quantity.

[0155] In one implementation, the first photometric result is obtained by the sample measurement component measuring the first calibrator using the first detection parameters;

[0156] The second and third optical measurement results are obtained by the sample measurement component measuring the second calibrator using the first and second detection parameters, respectively.

[0157] The fourth photometric result is obtained by the sample measurement component measuring the third calibrator using the second detection parameters;

[0158] Wherein, the first detection parameter and the second detection parameter are different detection parameters;

[0159] The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

[0160] The sample analyzer provided by this invention, in the calibration of the first item, uses different detection parameters to calibrate calibrators of different concentrations to obtain different photometric results, and obtains the calibration data of the first item based on the known concentrations of these calibrators and the photometric results, thereby enabling the calibration data of the first item to meet the accurate calibration requirements of samples with different concentration ranges. Furthermore, in the calibration of the first item, the second and third photometric results are obtained by the sample measurement component performing at least one second sub-calibration process of the first item on the second calibrator using the first and second detection parameters. That is, the overlapping areas of calibrator concentrations with different detection parameters are detected using the same calibrator to obtain two photometric results; that is, different detection parameters share the calibrator in the overlapping areas of calibrator concentrations, which helps to reduce the number of calibrators. Attached Figure Description

[0161] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0162] Figure 1 This is a schematic diagram of the first sub-calibration process provided in an embodiment of the present invention;

[0163] Figure 2 This is a schematic diagram of the principle of the second sub-calibration process provided in an embodiment of the present invention;

[0164] Figure 3 This is a schematic diagram of the principle of the third sub-calibration process provided in the embodiment of the present invention;

[0165] Figure 4 This is a schematic diagram of a sample analyzer with two optical measurement components provided in an embodiment of the present invention;

[0166] Figure 5 This is a schematic diagram of a sample analyzer with an optical measurement component provided in an embodiment of the present invention.

[0167] Explanation of reference numerals: 10, Sample analyzer; 100, Sample measurement component; 110, Sample dispensing component; 120, Reagent dispensing component; 130, Photometric component; 131, First photometric component; 132, Second photometric component; 140, Reaction support component; 150, Reagent storage component; 160, Sample injection component; 200, Controller; 20, Reaction container. Detailed Implementation

[0168] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0169] The sample analyzer provided in this embodiment of the invention is suitable for expanding the measurable concentration range of a target analyte by using at least one of the following methods: different components and / or reagents of different concentrations, different photometric components, different wavelengths of light, different reaction times, different blank times, and different methodologies (turbidimetric and colorimetric methods).

[0170] Reference Figures 1 to 5 As shown, the sample analyzer 10 provided in the first aspect of the present invention includes a sample measurement component 100, which is used to perform a sample measurement process on a sample to measure the target analyte in the sample. The sample is a sample collected from a human or animal.

[0171] In one implementation, the sample measurement component 100 is also used to perform a calibration procedure on a calibrator containing a target analyte and whose concentration is known. In this embodiment, the sample analyzer 10, in addition to measuring samples, requires periodic calibration using calibrators. The data obtained from the sample measurement is then calibrated based on the calibration data to obtain the sample detection results, thereby ensuring the accuracy of the sample detection results.

[0172] In one implementation, the sample measurement component 100 is used to perform a first-item calibration procedure on a calibrator containing a target analyte and whose concentration is known; and to perform a first-item sample measurement procedure on a sample used to detect the target analyte. In specific applications, the sample measurement component 100 can also be used to perform a second-item calibration procedure and a second-item sample measurement procedure, a third-item calibration procedure and a third-item sample measurement procedure, as well as calibration procedures and sample measurement procedures for other items, that is, the sample analyzer 10 can perform calibration and sample measurement for multiple items.

[0173] In one implementation, the sample analyzer 10 further includes a controller 200. The controller 200 is configured to perform the following calibration procedure for the first item: control the sample measurement component 100 to perform at least one first sub-calibration procedure of the first item on the first calibrator using the first detection parameters to obtain a first photometric result; control the sample measurement component 100 to perform at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameters and the second detection parameters to obtain a second photometric result and a third photometric result, wherein each second sub-calibration procedure of the first item is performed by the sample measurement component 100 on the same second calibrator using the first detection parameters and the second detection parameters; control the sample measurement component 100 to perform at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters to obtain a fourth photometric result; and obtain first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second and third photometric results, and the concentration of the target analyte in the third calibrator and the fourth photometric result. In this embodiment, the concentration of the target analyte in the second calibrator is greater than that in the first calibrator but less than that in the third calibrator; the first and second detection parameters are different. This implementation scheme uses different detection parameters to perform the calibration and sample measurement procedures, which can broaden the measurable range of the target analyte. For example, one detection parameter may have high accuracy for low concentration range measurements, while another may have high accuracy for high concentration range measurements, thus enabling the sample analyzer 10 to meet a wider range of accurate measurement requirements. Since at least some calibrators are shared when using different detection parameters to perform the calibration procedure (i.e., calibrating the same second calibrator with different detection parameters yields photometric results corresponding to different detection parameters), the number of calibrators can be reduced.

[0174] In one implementation, the controller 200 is also configured to perform the following sample measurement procedure for the first item: controlling the sample measurement component 100 to perform the sample measurement procedure for the same sample used to detect the target analyte using a first detection parameter and a second detection parameter, obtaining sample photometric results, and obtaining the detection result of the concentration of the target analyte in the sample based on the sample photometric results and first calibration data. The first calibration data can be used to calibrate the sample photometric results to obtain accurate sample detection results.

[0175] In one implementation, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameters to obtain a first photometric result. This includes: the control sample measurement component 100 performs a first sub-calibration process of the first item on the first calibrator for a first number of times using the first detection parameters to obtain a first photometric result. The control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameters and the second detection parameters to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration process of the first item on the second calibrator for a second number of times using the first detection parameters and the second detection parameters to obtain a second photometric result and a third photometric result. In each second sub-calibration process of the first item in the second number of times the first item is performed by the sample measurement component 100 on the same second calibrator using the first detection parameters and the second detection parameters. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters to obtain a fourth photometric result. This includes: the control sample measurement component 100 performs a third sub-calibration procedure of the first item on the third calibrator using the second detection parameters for a third time to obtain a fourth photometric result. The second result is greater than or equal to the first result, and greater than or equal to the third result, but less than the sum of the first and third results. In this embodiment, the number of calibration repetitions for calibrators sharing different detection parameters is set to be less than the sum of the number of calibration repetitions for each detection parameter individually. That is, the number of times the second sub-calibration procedure is performed is less than the sum of the number of times the first and third sub-calibration procedures are performed. This reduces the number of calibration repetitions, thereby improving calibration efficiency and reducing calibrator consumption.

[0176] As one implementation method, the first, second, and third counts are all greater than or equal to two. A single detection may be affected by various factors such as environment, instrument, and operation, leading to randomness in the photometric results. Repeated detections can reduce this random error, thereby making the photometric results more stable and reliable.

[0177] In one implementation, the first number is equal to the third number. Of course, in specific applications, as an alternative implementation, the first number can also be greater than or less than the third number.

[0178] As a first embodiment for obtaining the first photometric result, the second photometric result, the third photometric result, and the fourth photometric result, the control sample measurement component 100 performs a first sub-calibration process of the first item for the first number of times on the first calibrator through the first detection parameter to obtain the first photometric result, including: the control sample measurement component 100 performs a first sub-calibration process of the first item for the first number of times on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value equal to the first number of times, and calculates the average value of the first initial photometric value equal to the first number of times to obtain the first photometric result of the first calibrator of that concentration. The aforementioned control sample measurement component 100 performs a second sub-calibration process on the second calibrator for the second number of the first item using the first detection parameter and the second detection parameter to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration process on the second calibrator of the same concentration for the second number of the first item using the first detection parameter and the second detection parameter to obtain a second initial photometric value and a third initial photometric value equal to the second number of ... third photometric value of the second number of the second number of the third number of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the third number of the second number of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the third number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second The aforementioned control sample measurement component 100 performs a third sub-calibration procedure on the third calibrator for the first item for the third time using the second detection parameters to obtain a fourth photometric result. This includes: the control sample measurement component 100 performs a third sub-calibration procedure on the third calibrator of the same concentration for the third time using the second detection parameters to obtain a fourth initial photometric value equal to the third number of times; and averages the fourth initial photometric values ​​equal to the third number of times ...

[0179] In a second implementation of obtaining the first, second, third, and fourth photometric results, the first, second, and third numbers are all odd numbers greater than or equal to three. The control sample measurement component 100 performs a first sub-calibration process of the first item of the first number on the first calibrator using the first detection parameters to obtain the first photometric result. This includes: the control sample measurement component 100 performs a first sub-calibration process of the first item of the first number on the first calibrator of the same concentration using the first detection parameters to obtain a first initial photometric value equal to the first number. The first initial photometric value, which is the middle value among the first initial photometric values ​​equal to the first number, is taken as the first photometric result of the first calibrator of that concentration. The aforementioned control sample measurement component 100 performs a second sub-calibration process on the second calibrator for the second number of first items using the first detection parameter and the second detection parameter to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration process on the second calibrator of the same concentration for the second number of first items using the first detection parameter and the second detection parameter to obtain a second initial photometric value and a third initial photometric value equal to the second number of second initial photometric values. The second initial photometric value, which is the middle value among the second initial photometric values ​​equal to the second number of second initial photometric values, is taken as the second photometric result of the second calibrator of that concentration. The third initial photometric value, which is the middle value among the third initial photometric values ​​equal to the second number of third initial photometric values, is taken as the third photometric result of the second calibrator of that concentration. The aforementioned control sample measurement component 100 performs a third sub-calibration process of the first item for the third time on the third calibrator using the second detection parameters to obtain a fourth photometric result. This includes: the control sample measurement component 100 performs a third sub-calibration process of the first item for the third time on the third calibrator of the same concentration using the second detection parameters to obtain a fourth initial photometric value equal to the third number of times. The median value among the fourth initial photometric values ​​equal to the third number of times is taken as the fourth photometric result for the third calibrator of that concentration. The first, second, and third times can be, for example, three, five, or seven times. In this embodiment, the method of taking the median value of multiple initial photometric values ​​obtained by repeatedly calibrating each concentration of calibrator (or the extreme value removal method) to obtain the photometric result for each calibrator can also help ensure the accuracy of the photometric results.

[0180] As a third implementation method for obtaining the first photometric result, the second photometric result, the third photometric result, and the fourth photometric result, the first number, the second number, and the third number are all greater than or equal to four. The control sample measurement component 100 performs a first sub-calibration process of the first item of the first number on the first calibrator through the first detection parameter to obtain the first photometric result. This includes: the control sample measurement component 100 performs a first sub-calibration process of the first item of the first number on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value with a quantity equal to the first number; and averages the remaining first initial photometric values ​​(excluding the maximum and minimum values) among the first initial photometric values ​​with a quantity equal to the first number to obtain the first photometric result of the first calibrator of that concentration. The aforementioned control sample measurement component 100 performs a second sub-calibration process on the second calibrator using a second number of first items with a first detection parameter and a second detection parameter to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration process on the second calibrator of the same concentration using a second number of first items with a first detection parameter and a second number of third initial photometric values ​​equal to the second number; the average value of the remaining second initial photometric values ​​(excluding the maximum and minimum values) equal to the second number is calculated to obtain the second photometric result of the second calibrator at that concentration; and the average value of the remaining third initial photometric values ​​(excluding the maximum and minimum values) equal to the second number is calculated to obtain the third photometric result of the second calibrator at that concentration. The aforementioned control sample measurement component 100 performs a third sub-calibration process of the first item for the third time on the third calibrator using the second detection parameters to obtain a fourth photometric result. This includes: the control sample measurement component 100 performs a third sub-calibration process of the first item for the third time on the third calibrator of the same concentration using the second detection parameters to obtain a fourth initial photometric value equal to the third number of values; and averages the remaining fourth initial photometric values ​​(excluding the maximum and minimum values) to obtain the fourth photometric result for the third calibrator of that concentration. In this embodiment, the multiple initial photometric values ​​obtained by repeatedly calibrating each concentration of calibrator are combined with the extreme value removal method and the averaging method to obtain the photometric result for each calibrator. This also helps to ensure the accuracy of the photometric results.

[0181] In one implementation, the control sample measurement component 100 performs at least one first sub-calibration procedure of the first item on the first calibrator using the first detection parameters to obtain a first photometric result. This includes: the control sample measurement component 100 performs a first sub-calibration procedure of the first item for at least two first calibrators with different concentrations using the first detection parameters to obtain at least two first photometric results corresponding one-to-one with the at least two first calibrators. The control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameters and the second detection parameters to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration procedure of the first item for at least one second calibrator to obtain at least one second photometric result corresponding one-to-one with the at least one second calibrator and at least one third photometric result corresponding one-to-one with the at least one second calibrator. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters to obtain a fourth photometric result. This includes: the control sample measurement component 100 performs a third sub-calibration procedure of the first item on at least two third calibrators with different concentrations using the second detection parameters to obtain at least two fourth photometric results that correspond one-to-one with at least two third calibrators. The aforementioned method of obtaining first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second and third photometric results, and the concentration of the target analyte in the third calibrator and the fourth photometric result includes: obtaining first calibration data based on the concentration of the target analyte in at least two first calibrators and at least two first photometric results, the concentration of the target analyte in at least one second calibrator and at least one second and at least one third photometric result, and the concentration of the target analyte in at least two third calibrators and at least two fourth photometric results. In this embodiment, the concentrations of the target analyte in at least two first calibrators with different concentrations are all within a first preset concentration range; the concentrations of the target analyte in at least one second calibrator are within a second preset concentration range; and the concentrations of the target analyte in at least two third calibrators with different concentrations are all within a third preset concentration range. Each concentration value in the second preset concentration range is greater than each concentration value in the first preset concentration range and less than each concentration value in the third preset concentration range. In this embodiment, when different detection parameters are used for calibration, each detection parameter in the non-shared calibrator portion is calibrated using at least two calibrators with different concentrations. This allows for the acquisition of more photometric results, thereby improving the accuracy of the obtained calibration data.

[0182] In one implementation, the control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using a first detection parameter and a second detection parameter. This includes performing at least one of the following processes: the control sample measurement component 100 measures the second calibrator dispensed into a reaction vessel 20 (i.e., the second reaction vessel described below) using the first detection parameter to obtain a second initial photometric value; the control sample measurement component 100 measures the second calibrator in the reaction vessel 20 using the second detection parameter to obtain a third initial photometric value. Obtaining the second photometric result includes obtaining a second photometric result based on the second initial photometric value obtained in the at least one second sub-calibration process of the first item. Obtaining the third photometric result includes obtaining a third photometric result based on the third initial photometric value obtained in the at least one second sub-calibration process of the first item. In this implementation scheme, during each second sub-calibration process, the same second calibrator allocated to the same second reaction vessel is measured using the first and second detection parameters to obtain a second initial photometric value and a third initial photometric value, respectively. Then, based on the second initial photometric values ​​obtained from all second sub-calibration processes, a second photometric result is obtained. Similarly, based on the third initial photometric values ​​obtained from all second sub-calibration processes, a third photometric result is obtained. That is, in each second sub-calibration process, the same calibrator allocated to the same reaction vessel 20 is calibrated using both the first and second detection parameters. The first and second detection parameters are not used to calibrate the calibrators in the two reaction vessels 20 separately. Furthermore, each second sub-calibration process yields a second initial photometric value corresponding to the first detection parameter and a third initial photometric value corresponding to the second detection parameter. These second and third initial photometric values ​​are not obtained by calibrating the calibrators in the two reaction vessels 20 separately. This allows for the reduction of the number of calibrators by sharing the calibrator.

[0183] Of course, in specific applications, the implementation of the second sub-calibration process by the sample measurement component 100 using the first and second detection parameters to perform the second sub-calibration process on the second calibrator is not limited to measuring the reaction liquid in the same reaction vessel as described above. For example, as an alternative implementation, when the sample measurement component 100 performs the second sub-calibration process on the second calibrator using the first and second detection parameters, the first and second detection parameters may not be used to measure the second calibrator in the same reaction vessel 20. Instead, the first detection parameter is used to measure the second calibrator allocated to one reaction vessel 20 (i.e., the second reaction vessel described below) to obtain a second initial photometric value. Then, the second calibrator (or the reaction liquid containing the second calibrator) in the reaction vessel 20 is transferred to another reaction vessel 20 (i.e., the third reaction vessel described below, which is independent of the second reaction vessel). The second detection parameter is then used to measure the second calibrator (or the reaction liquid containing the second calibrator) in the other reaction vessel 20 to obtain a third initial photometric value. The aforementioned control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter. This includes performing at least one of the following processes: the control sample measurement component 100 measures the second calibrator allocated to one reaction container 20 (i.e., the second reaction container described below) using the first detection parameter to obtain a second initial photometric value; the control sample measurement component 100 measures the second calibrator (or the reaction solution containing the second calibrator) transferred from the reaction container 20 to another reaction container 20 (i.e., the third reaction container described below) using the second detection parameter to obtain a third initial photometric value. Since this alternative embodiment also uses different detection parameters to calibrate the same second calibrator, obtaining photometric results corresponding to different detection parameters, the number of calibrators can also be reduced by sharing the calibrator.

[0184] In one implementation, the control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using a first detection parameter and a second detection parameter, including: performing at least two of the following processes: the control sample measurement component 100 measures the second calibrator dispensed into a reaction vessel 20 using the first detection parameter to obtain a second initial photometric value; the control sample measurement component 100 measures the second calibrator in the reaction vessel 20 using the second detection parameter, or the control sample measurement component 100 measures the second calibrator (or the reaction solution containing the second calibrator) transferred from the reaction vessel 20 to another reaction vessel 20 using the second detection parameter to obtain a third initial photometric value. Obtaining the second photometric result includes obtaining a second photometric result based on the second initial photometric value obtained in at least two second sub-calibration processes of the first item. Obtaining the third photometric result includes obtaining a third photometric result based on the third initial photometric value obtained in at least two second sub-calibration processes of the first item. In this implementation scheme, the second photometric result is obtained by analyzing the second initial photometric value obtained by measuring the first detection parameter in at least two second sub-calibration processes, and the third photometric result is obtained by analyzing the third initial photometric value obtained by measuring the second detection parameter in at least two second sub-calibration processes. This helps to reduce the impact of accidental factors in the calibration process on the calibration results, thereby helping to ensure the accuracy, stability and reliability of the calibration data.

[0185] In one embodiment, the sample measurement assembly 100 includes a sample dispensing component 110, a reagent dispensing component 120, and an optical measurement component 130. The sample dispensing component 110 is used to add calibrators into the reaction container 20, the reagent dispensing component 120 is used to add reagents into the reaction container 20, and the optical measurement component 130 is used to perform optical measurements on the reaction solution within the reaction container 20, which is composed of at least the calibrators and reagents. Specifically, the sample dispensing component 110 is used to add a first calibrator, a second calibrator, a third calibrator, a sample, and a sample into the reaction container 20. The reagent dispensing component 120 is used to add reagents into the reaction container 20. The optical measurement component 130 is used to perform optical measurements on the reaction solution within the reaction container 20, which is composed of at least one of the first calibrator, the second calibrator, the third calibrator, a sample, and a reagent. The sample dispensing component 110 primarily performs the function of dispensing calibrators and samples. The reagent dispensing component 120 primarily performs the function of dispensing reagents. The optical measurement component 130 is mainly used to realize the optical measurement function of the reaction solution.

[0186] As one implementation method, the different detection parameters mentioned above include any of the following: different components and / or different concentrations of reagents, different photometric components 130, different wavelengths of light, different reaction times, and different blank times. The sample measurement assembly 100 includes the photometric component 130. Reagents are used to react with samples or calibrators to prepare a reaction solution. Reaction time refers to the reaction time between the reagent and the sample, or the reaction time between the reagent and the calibrator, or the interval between the blank measurement point and the reaction measurement point (i.e., the final measurement point of the sample). Blank time refers to the interval between the blank test time point and the start of the measurement cycle. The photometric component 130 is used to measure the reaction solution with light of a preset wavelength. According to the applicant's research, samples or calibrators with different target concentrations can be accurately measured by reacting with reagents of different components and / or different concentrations, by using different photometric components 130, by measuring light of different wavelengths, by setting different reaction times, and by setting different blank times. Therefore, by using different components and / or different concentrations of reagents, different photometric components 130, different wavelengths of light, different reaction times, and different blank times as different detection parameters to measure calibrators or samples of different concentrations, the measurable range of the target analyte can be broadened.

[0187] Reference Figures 1 to 5As shown, in a first embodiment of the above-mentioned different detection parameters, when the above-mentioned different detection parameters include reagents with different components and / or different concentrations, the above-mentioned control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator through the first detection parameters, including: performing at least one of the following processes: controlling the reagent dispensing component 120 to add the first reagent into the first reaction container; controlling the sample dispensing component 110 to add the first calibrator into the first reaction container; controlling the photometry component 130 to perform optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and the first reagent, to obtain a first initial photometry value. The above-mentioned obtaining the first photometry result includes: obtaining the first photometry result based on the first initial photometry value obtained in the above-mentioned at least one first sub-calibration process of the first item, for example, the first photometry result can be obtained by using the extreme value removal method and / or the averaging method on the first initial photometry values ​​obtained in all the first sub-calibration processes. The aforementioned control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameter and the second detection parameter. This includes performing at least one of the following procedures: the control reagent dispensing component 120 adds the first reagent into the second reaction container; the control sample dispensing component 110 adds the second calibrator into the second reaction container; the control photometry component 130 performs optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain a second initial photometry value; the control reagent dispensing component 120 adds the second reagent into the second reaction container; and the control photometry component 130 performs optical measurement on the third reaction liquid in the second reaction container, which is at least composed of the second calibrator, the first reagent, and the second reagent (i.e., the third reaction liquid is at least composed of the second reagent and the second reaction liquid), to obtain a third initial photometry value. Obtaining the second photometry result includes obtaining the second photometry result based on the second initial photometry value obtained in the aforementioned at least one second sub-calibration procedure of the first item. For example, the second photometry result can be obtained by using the extreme value removal method and / or the averaging method on the second initial photometry values ​​obtained in all second sub-calibration procedures. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in at least one of the second sub-calibration procedures of the first item. For example, the third photometric result can be obtained by using the extremum removal method and / or the averaging method on the third initial photometric values ​​obtained in all the second sub-calibration procedures. In performing one second sub-calibration procedure, the first reagent, the second calibrator, and the second reagent need to be sequentially dispensed into the same second reaction vessel, and the different reaction solutions in the same second reaction vessel need to be measured separately to obtain the second initial photometric value and the third initial photometric value.The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following procedures: the control reagent dispensing component 120 adds the first reagent into the fourth reaction container; the control sample dispensing component 110 adds the third calibrator into the fourth reaction container; the control reagent dispensing component 120 adds the second reagent into the fourth reaction container; and the control photometry component 130 performs optical measurement on the fourth reaction solution in the fourth reaction container, which is at least composed of the third calibrator, the first reagent, and the second reagent, to obtain a fourth initial photometric value. Obtaining the fourth photometric result includes obtaining the fourth photometric result based on the fourth initial photometric value obtained in the aforementioned at least one third sub-calibration procedure of the first item. For example, the fourth photometric result can be obtained by using the extremum removal method and / or the averaging method on the fourth initial photometric values ​​obtained in all third sub-calibration procedures. The first reagent and the second reagent differ in at least one of the following aspects: composition and concentration. This implementation scheme innovatively proposes using reagents with different components and / or concentrations to react with calibrators, obtaining different reaction solutions. Optical measurements are then performed on each of these different reaction solutions. For calibrators of different concentrations, the optical measurements of the different reaction solutions are used to obtain optical measurement results corresponding to those calibrators. Based on the optical measurement results of calibrators of different concentrations, calibration data (including but not limited to calibration curves) for different concentration ranges are obtained. Specifically, different reagents are added at different times during the measurement cycle to prepare different reaction solutions, and the optical measurement component 130 is used to measure the different reaction solutions at different stages to obtain calibration data for different concentration ranges. Using this calibration data to calibrate the optical measurement results of samples with different concentration ranges can yield accurate detection results, thereby expanding the measurable range of the sample analyzer 10. This method is simple to implement and can reduce the need for structural improvements to the sample analyzer 10. Furthermore, in this implementation scheme, the measurement cycle for different detection parameters is the same. Two different components and / or different concentrations of a set of reagents can complete two reactions, and the first reagent will not affect the subsequent reaction. Only the measurement data at different stages are taken as the photometric result corresponding to the detection parameter. In this way, the calibration of overlapping areas of different concentration ranges can be achieved within one measurement cycle by using different detection parameters with shared calibrators, thereby reducing the number of calibrators.

[0188] Blank measurement points can be one of the following: immediately after adding the first reagent and calibrator or immediately after adding the first reagent and sample; or after adding the first reagent and calibrator or after adding the first reagent and sample, and before adding the second reagent; or after adding the first reagent, and before adding the calibrator or sample; or immediately after adding the first reagent and calibrator, the second reagent, or immediately after adding the first reagent and sample, the second reagent, and before the second reagent has fully reacted with the sample or before it has fully reacted with the calibrator.

[0189] The reaction measurement point can be one of the following: after adding the first reagent, calibrator, and second reagent and allowing them to react fully, or after adding the first reagent, sample, and second reagent and allowing them to react fully; or the end point of the measurement cycle.

[0190] In the above scheme, during the calibration process, the reagent is sequentially distributed into the reaction vessel 20 in the order of first reagent, calibrator (first calibrator, second calibrator, or third calibrator), and second reagent; during the sample determination process, the reagent is sequentially distributed into the reaction vessel 20 in the order of first reagent, sample, and second reagent. That is, the first reagent is distributed first, then the calibrator or sample is distributed, and then the second reagent is distributed. Of course, in specific applications, the order of distribution of the first reagent, calibrator, second reagent, and sample is not limited to this. For example, as an alternative implementation, the calibrator or sample may be distributed first, then the first reagent, and then the second reagent. That is, during the calibration process, the reagent (first calibrator, second calibrator, or third calibrator), first reagent, and second reagent may be sequentially distributed into the reaction vessel 20; correspondingly, during the sample determination process, the sample, first reagent, and second reagent may be sequentially distributed into the reaction vessel 20.

[0191] In the above scheme, when the different detection parameters include reagents with different components and / or different concentrations, the second initial optical measurement value and the third initial optical measurement value are obtained by the optical measurement component 130 sequentially performing optical measurements on the second reaction liquid made of the second calibrator and the first reagent, and the third reaction liquid made of the second reaction liquid and the second reagent in the same reaction container. Of course, in specific applications, as an alternative implementation scheme, when the different detection parameters include reagents with different components and / or different concentrations, the second initial optical measurement value and the third initial optical measurement value can also be obtained by the optical measurement component 130 sequentially performing optical measurements on the second reaction liquid made of the second calibrator and the first reagent, and the third reaction liquid made of the second reaction liquid and the second reagent in different reaction containers. That is, the optical measurement component 130 first performs optical measurements on the second reaction liquid made of the second calibrator and the first reagent in one reaction container 20 to obtain the second initial optical measurement value, and then transfers the second reaction liquid to another reaction container 20, and the optical measurement component 130 then performs optical measurements on the third reaction liquid made of the second reaction liquid and the second reagent in the other reaction container 20 to obtain the third initial optical measurement value. Specifically, in this alternative embodiment, the control sample measurement component 100 performs at least one second sub-calibration procedure for the second calibrator using a first detection parameter and a second detection parameter, including: performing at least one of the following procedures: controlling the reagent dispensing component 120 to add a first reagent into a second reaction container; controlling the sample dispensing component 110 to add a second calibrator into a second reaction container; controlling the photometry component 130 to perform optical measurements on a second reaction solution in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain a second initial photometric value; controlling the reagent dispensing component 120 to add the second reagent into a third reaction container, which is independent of the second reaction container; controlling the pipetting component to transfer the second reaction solution from the second reaction container to the third reaction container; and controlling the photometry component 130 to perform optical measurements on a third reaction solution in the third reaction container, which is at least composed of the second reagent and the second reaction solution, to obtain a third initial photometric value. The pipetting component can be either the sample dispensing component 110 or the reagent dispensing component 120, or it can be a component independent of both the sample dispensing component 110 and the reagent dispensing component 120.

[0192] Reference Figure 4As shown, in a second embodiment of the different detection parameters, when the different detection parameters include different photometric components 130, the sample measurement assembly 100 includes a first photometric component 131 and a second photometric component 132. The control of the sample measurement assembly 100 to perform at least one first sub-calibration process of a first item on the first calibrator using the first detection parameters includes: performing at least one process of controlling the first photometric component 131 to perform optical measurement on the reaction liquid in the first reaction vessel, which is at least composed of the first calibrator and reagents, to obtain a first initial photometric value. Obtaining the first photometric result includes: obtaining the first photometric result based on the first initial photometric value obtained in the at least one first sub-calibration process of the first item. The aforementioned control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter. This includes performing at least one of the following processes: controlling the first photometric component 131 to perform optical measurement on the reaction liquid in the second reaction vessel, which is made from at least the second calibrator and reagent, to obtain a second initial photometric value; controlling the second photometric component 132 to perform optical measurement on the reaction liquid in the second reaction vessel, which is made from at least the second calibrator and reagent, to obtain a third initial photometric value. Obtaining the second photometric result includes obtaining the second photometric result based on the second initial photometric value obtained in the aforementioned at least one second sub-calibration process of the first item. Obtaining the third photometric result includes obtaining the third photometric result based on the third initial photometric value obtained in the aforementioned at least one second sub-calibration process of the first item. In performing one second sub-calibration process, the second calibrator and reagent need to be sequentially dispensed into the same second reaction vessel, and the first photometric component 131 and the second photometric component 132 need to measure the reaction liquid in the same second reaction vessel to obtain the second initial photometric value and the third initial photometric value, respectively. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters, including: performing at least one procedure as follows: controlling the second photometric component 132 to perform optical measurements on the reaction solution in the fourth reaction vessel, which is made of at least the third calibrator and reagents, to obtain a fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the aforementioned at least one third sub-calibration procedure of the first item. Wherein, one of the first photometric component 131 and the second photometric component 132 is a transmission light detector, and the other is a scattering light detector.This implementation scheme uses different photometric components 130 to measure calibrators or samples of different concentrations. Specifically, it uses different photometric components 130 to perform optical measurements on the reaction solution made from calibrators and reagents, thereby obtaining photometric values ​​of the reaction solution by different photometric components 130. Based on the photometric values ​​of different photometric components 130, calibration data for different concentration ranges can be obtained. Using this calibration data, the photometric results of samples with different concentration ranges can be calibrated to ensure the accuracy of the detection results for samples with different concentration ranges, thereby also achieving the purpose of broadening the measurement range of the sample analyzer 10.

[0193] In the above scheme, when the different detection parameters include different photometric components 130, the second initial photometric value and the third initial photometric value are obtained by the first photometric component 131 and the second photometric component 132 optically measuring the reaction solution made of the second calibrator and reagent in the same reaction vessel, respectively. Of course, in specific applications, as an alternative implementation scheme, when the different detection parameters include different photometric components 130, the second initial photometric value and the third initial photometric value can also be obtained by the first photometric component 131 and the second photometric component 132 optically measuring the reaction solution made of the same second calibrator and reagent in different reaction vessels, respectively. That is, the first photometric component 131 first optically measures the reaction solution made of the second calibrator and reagent in one reaction vessel 20 to obtain the second initial photometric value, and then transfers the second reaction solution to another reaction vessel 20, and the second photometric component 132 then optically measures the reaction solution in the other reaction vessel 20 to obtain the third initial photometric value. Specifically, in this alternative embodiment, the aforementioned control sample measurement component 100 performs at least one second sub-calibration procedure for the second calibrator using a first detection parameter and a second detection parameter. This includes performing at least one of the following procedures: controlling a first photometric component 131 to perform optical measurements on the reaction solution in the second reaction container, which is composed of at least the second calibrator and reagents, to obtain a second initial photometric value; controlling a pipetting component to transfer the reaction solution from the second reaction container to a third reaction container independent of the second reaction container; and controlling a second photometric component 132 to perform optical measurements on the reaction solution in the third reaction container to obtain a third initial photometric value. The pipetting component can be a sample dispensing component 110 or a reagent dispensing component 120, or it can be a component independent of both the sample dispensing component 110 and the reagent dispensing component 120.

[0194] Reference Figures 1 to 5As shown, in a third embodiment of the different detection parameters described above, when the different detection parameters include different components and / or different concentrations of reagents and different photometric components 130, the sample measurement assembly 100 includes a first photometric component 131 and a second photometric component 132. The above-described control of the sample measurement assembly 100 to perform at least one first sub-calibration process of the first item on the first calibrator using the first detection parameters includes: performing at least one of the following processes: controlling the reagent dispensing component 120 to add the first reagent into the first reaction container; controlling the sample dispensing component 110 to add the first calibrator into the first reaction container; controlling the first photometric component 131 to perform optical measurement on the first reaction liquid in the first reaction container, which is at least composed of the first calibrator and the first reagent, to obtain a first initial photometric value. Obtaining the first photometric result includes: obtaining the first photometric result based on the first initial photometric value obtained in the above-described at least one first sub-calibration process of the first item. The aforementioned control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following procedures: controlling the reagent dispensing component 120 to add the first reagent into the second reaction container; controlling the sample dispensing component 110 to add the second calibrator into the second reaction container; controlling the first photometric component 131 to perform optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain a second initial photometric value; controlling the reagent dispensing component 120 to add the second reagent into the second reaction container; controlling the second photometric component 132 to perform optical measurement on the third reaction liquid in the second reaction container, which is at least composed of the second calibrator, the first reagent, and the second reagent, to obtain a third initial photometric value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the aforementioned at least one second sub-calibration procedure of the first item. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the aforementioned at least one second sub-calibration procedure of the first item. In performing a second sub-calibration process, the first reagent, the second calibrator, and the second reagent need to be sequentially dispensed into the same second reaction vessel. The first photometric component 131 and the second photometric component 132 need to measure the different reaction solutions in the same second reaction vessel to obtain the second initial photometric value and the third initial photometric value.The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following procedures: controlling the reagent dispensing component 120 to add the first reagent into the fourth reaction container; controlling the sample dispensing component 110 to add the third calibrator into the fourth reaction container; controlling the reagent dispensing component 120 to add the second reagent into the fourth reaction container; controlling the second photometric component 132 to perform optical measurement on the fourth reaction liquid in the fourth reaction container, which is at least composed of the third calibrator, the first reagent, and the second reagent, to obtain a fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the aforementioned at least one third sub-calibration procedure of the first item. The first reagent and the second reagent differ in at least one of the following aspects: composition, concentration; one of the first photometric component 131 and the second photometric component 132 is a transmission light detector, and the other is a scattering light detector. In this implementation scheme, by adding different reagents at different times during the measurement cycle and using different photometric components 130 to measure different reaction solutions at different stages, calibration data with different concentration ranges can be obtained. By using this calibration data to calibrate the photometric results of samples with different concentration ranges, accurate detection results can be obtained, thereby also achieving the purpose of broadening the measurable range of the sample analyzer 10.

[0195] In the above scheme, when the different detection parameters include different components and / or different concentrations of reagents and different photometric components 130, the second initial photometric value and the third initial photometric value are obtained by different photometric components 130 sequentially performing optical measurements on the second reaction liquid made of the second calibrator and the first reagent, and the third reaction liquid made of the second reaction liquid and the second reagent in the same reaction vessel. Of course, in specific applications, as an alternative implementation, when the above-mentioned different detection parameters include different components and / or different concentrations of reagents and different photometric components 130, the second initial photometric value and the third initial photometric value can also be obtained by different photometric components 130 performing optical measurements on the second reaction liquid made of the second calibrator and the first reagent in different reaction containers, and the third reaction liquid made of the second reaction liquid and the second reagent, respectively. That is, one photometric component 130 first performs optical measurements on the second reaction liquid made of the second calibrator and the first reagent in one reaction container 20 to obtain the second initial photometric value, and then transfers the second reaction liquid to another reaction container 20, and another photometric component 130 then performs optical measurements on the third reaction liquid made of the second reaction liquid and the second reagent in the other reaction container 20 to obtain the third initial photometric value. Specifically, in this alternative embodiment, the control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using a first detection parameter and a second detection parameter, including: performing at least one of the following procedures: controlling the reagent dispensing component 120 to add the first reagent into the second reaction container; controlling the sample dispensing component 110 to add the second calibrator into the second reaction container; controlling the first photometric component 131 to perform optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain a second initial photometric value; controlling the reagent dispensing component 120 to add the second reagent into a third reaction container independent of the second reaction container; controlling the pipetting component to transfer the second reaction liquid from the second reaction container to the third reaction container; and controlling the second photometric component 132 to perform optical measurement on the third reaction liquid in the third reaction container, which is at least composed of the second reagent and the second reaction liquid, to obtain a third initial photometric value. The pipetting component can be either the sample dispensing component 110 or the reagent dispensing component 120, or it can be a component independent of the sample dispensing component 110 and the reagent dispensing component 120.

[0196] In one implementation method, the photometric analysis of the reaction solution formed by the reaction of the first reagent and the calibrator is performed using turbidimetry; the photometric analysis of the reaction solution formed by the reaction of the second reagent and the calibrator is performed using colorimetry. Turbidimetry provides high accuracy for detecting low concentrations of target substances, while colorimetry provides high accuracy for detecting high concentrations of target substances.

[0197] In one implementation, the first optical measuring component 131 is a scattered light detector, and the second optical measuring component 132 is a transmitted light detector.

[0198] As a fourth implementation of the aforementioned different detection parameters, when the different detection parameters include light of different wavelengths, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameter, including: performing the following process for the first time: controlling the photometry component 130 to perform optical measurement of light of the first wavelength on the reaction liquid in the first reaction vessel, which is made of at least the first calibrator and reagents, to obtain a first initial photometry value. Obtaining the first photometry result includes: obtaining the first photometry result based on the first initial photometry value obtained in the first sub-calibration process of the first item at least once. The control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement of light of the first wavelength on the reaction liquid in the second reaction vessel, which is made of at least the second calibrator and reagents, to obtain a second initial photometry value; controlling the photometry component 130 to perform optical measurement of light of the second wavelength on the reaction liquid in the second reaction vessel, which is made of at least the second calibrator and reagents, to obtain a third initial photometry value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the second sub-calibration process of the first item at least once. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once. The control sample measurement component 100 performs at least one third sub-calibration process of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following processes: controlling the photometric component 130 to perform optical measurement of light of a second wavelength on the reaction liquid in the fourth reaction vessel, which is made of at least the third calibrator and reagents, to obtain a fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the third sub-calibration process of the first item at least once. Wherein, the second wavelength is greater than or less than the first wavelength. This implementation scheme measures the reaction solution using light of different wavelengths. Specifically, it performs optical measurements on the reaction solution using light of different wavelengths within the measurement period to obtain photometric values ​​for different wavelengths. Based on these measurements, calibration data for different concentration ranges is obtained. Using this calibration data to calibrate the photometric results for samples with different concentration ranges yields accurate detection results, thereby expanding the measurable concentration range of the sample analyzer 10. In specific applications, all wavelengths can be detected using a transmitted light detector, all wavelengths can be detected using a scattered light detector, or one wavelength can be detected using a transmitted light detector and the other wavelength using a scattered light detector.

[0199] In the above scheme, when the different detection parameters include light of different wavelengths, the second initial photometric value and the third initial photometric value are obtained by the photometric component 130 performing optical measurements of the first wavelength and the second wavelength on the reaction liquid made of the second calibrator and reagent in the same reaction container, respectively. Of course, in specific applications, as an alternative implementation scheme, when the different detection parameters include light of different wavelengths, the second initial photometric value and the third initial photometric value can also be obtained by the photometric component 130 performing optical measurements of the first wavelength and the second wavelength on the reaction liquid made of the second calibrator and reagent in different reaction containers, respectively. That is, the photometric component 130 first performs optical measurements of the first wavelength on the reaction liquid made of the second calibrator and reagent in one reaction container 20 to obtain the second initial photometric value, and then transfers the reaction liquid to another reaction container 20, and the photometric component 130 then performs optical measurements of the second wavelength on the reaction liquid in the other reaction container 20 to obtain the third initial photometric value. Specifically, in this alternative embodiment, the aforementioned control sample measurement component 100 performs at least one second sub-calibration procedure for the second calibrator using a first detection parameter and a second detection parameter. This includes performing at least one of the following procedures: controlling the photometry component 130 to perform optical measurement of a first wavelength of light on the reaction solution in the second reaction container, which is prepared from at least the second calibrator and reagents, to obtain a second initial photometry value; controlling the pipetting component to transfer the reaction solution from the second reaction container to a third reaction container; and controlling the photometry component 130 to perform optical measurement of a second wavelength of light on the reaction solution in the third reaction container to obtain a third initial photometry value. The pipetting component can be a sample dispensing component 110 or a reagent dispensing component 120, or it can be a component independent of the sample dispensing component 110 and the reagent dispensing component 120.

[0200] As a fifth implementation of the aforementioned different detection parameters, when the different detection parameters include different reaction times, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared by at least the first calibrator and reagent in the first reaction container under the first reaction time, to obtain a first initial photometry value. Obtaining the first photometry result includes: obtaining the first photometry result based on the first initial photometry value obtained in the aforementioned at least one first sub-calibration process of the first item. The control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared by at least the second calibrator and reagent in the second reaction container under the first reaction time, to obtain a second initial photometry value; controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared by at least the second calibrator and reagent in the second reaction container under the second reaction time, to obtain a third initial photometry value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the second sub-calibration process of the first item at least once. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once. The control sample measurement component 100 performs at least one third sub-calibration process of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following processes: controlling the photometric component 130 to perform optical measurement on the reaction solution prepared in the fourth reaction vessel by at least the third calibrator and reagent under the second reaction time, to obtain a fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the third sub-calibration process of the first item at least once. Wherein, the second reaction time is greater than or less than the first reaction time. This implementation scheme measures the reaction solution by setting different reaction times. Specifically, it performs optical measurements on the reaction solution prepared from calibrators and reagents at different time points within the measurement cycle to obtain photometric values ​​at different reaction stages. Based on the photometric values ​​of different concentrations of reaction solution at different reaction stages, calibration data for different concentration ranges is obtained. Using this calibration data to calibrate the photometric results of samples with different concentration ranges yields accurate detection results, thereby expanding the measurable concentration range of the sample analyzer 10. In practical applications, different reaction times can all be detected using a transmitted light detector, or all using a scattered light detector, or one reaction time can be detected using a transmitted light detector and the other using a scattered light detector.

[0201] As a sixth implementation of the aforementioned different detection parameters, when the different detection parameters include different blank durations, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared in the first reaction vessel by at least the first calibrator and reagent under the first blank duration, to obtain a first initial photometry value. Obtaining the first photometry result includes: obtaining the first photometry result based on the first initial photometry value obtained in the aforementioned at least one first sub-calibration process of the first item. The control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared in the second reaction vessel by at least the second calibrator and reagent under the first blank duration, to obtain a second initial photometry value; controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared in the second reaction vessel by at least the second calibrator and reagent under the second blank duration, to obtain a third initial photometry value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the second sub-calibration process of the first item at least once. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once. The control sample measurement component 100 performs at least one third sub-calibration process of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following processes: controlling the photometric component 130 to perform optical measurement on the reaction solution prepared in the fourth reaction vessel by at least the third calibrator and reagent under a second blank time, and obtaining a fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the third sub-calibration process of the first item at least once. Wherein, the second blank time is greater than or less than the first blank time. This implementation scheme measures the reaction solution by setting different blank durations. Specifically, different blank durations are set for calibrators of different concentrations within the measurement cycle to obtain photometric values ​​for different blank durations. Based on the photometric values ​​for different blank durations, calibration data for different concentration ranges is obtained. Using this calibration data to calibrate the photometric results of samples within different concentration ranges yields accurate detection results, thereby expanding the measurement range of the sample analyzer 10. In specific applications, different blank durations can all be detected using a transmitted light detector, or all using a scattered light detector, or one blank duration can be detected using a transmitted light detector and the other using a scattered light detector.

[0202] In one implementation, the sample dispensing component 110 includes a sample needle for adding calibrators into the reaction container 20, a reagent dispensing component 120 for adding reagents into the reaction container 20, and an optical measurement component 130 for performing optical measurements on the reaction solution in the reaction container 20, which is at least composed of calibrators and reagents. The aforementioned controlled sample measurement component 100 performs at least one first sub-calibration procedure for the first calibrator using a first detection parameter to obtain a first optical measurement result. This includes: controlling the sample needle to dispense the first calibrator of the same concentration into a first number of reaction containers 20; controlling the optical measurement component 130 to perform optical measurements on the reaction solution in the first number of reaction containers 20, which is at least composed of the first calibrators and reagents, to obtain a first number of first initial optical measurement values; and obtaining the first optical measurement result based on the first number of first initial optical measurement values. The aforementioned control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameter and the second detection parameter to obtain a second photometric result and a third photometric result. This includes: controlling the sample needle to dispense the second calibrator of the same concentration into a second number of reaction containers 20; controlling the photometric component 130 to perform optical measurements on the reaction solution in the second number of reaction containers 20, which is at least composed of the second calibrator and reagents, to obtain a second number of second initial photometric values ​​and a third number of third initial photometric values; obtaining a second photometric result based on the second number of second initial photometric values; and obtaining a third photometric result based on the second number of third initial photometric values. Furthermore, the photometric component 130 obtains both a second initial photometric value and a third initial photometric value for each reaction solution in the second number of reaction containers 20, which is at least composed of the second calibrator and reagents. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameter to obtain a fourth photometric result. This includes: controlling the sample needle to dispense the third calibrator of the same concentration into a third number of reaction containers 20; controlling the photometric component 130 to perform optical measurements on the reaction solution in the third number of reaction containers 20, which is composed of at least the calibrator and reagents, to obtain a third number of fourth initial photometric values; and obtaining a fourth photometric result based on the third number of fourth initial photometric values. The second number is greater than or equal to the first number, and greater than or equal to the third number, and less than the sum of the first and third numbers. In one dispensing action, the sample needle completes the action of dispensing the calibrator into one reaction container 20. The number of calibrators dispensed into a reaction container 20 is equal to the number of repeated dispensing actions for that calibrator. In this embodiment, the number of repeated dispensing actions for calibrators shared by different detection parameters is set to be less than the sum of the number of repeated dispensing actions for each detection parameter individually. This reduces the number of repeated dispensing actions, thereby improving calibration efficiency and reducing calibrator consumption.

[0203] In one implementation, the value of the first quantity is equal to the value of the first count; the value of the second quantity is equal to the value of the second count; and the value of the third quantity is equal to the value of the third count.

[0204] In one implementation, the sample analyzer 10 also includes a display, which is used to display at least the calibration result interface of the first item. After obtaining the first calibration data, the controller 200 is further configured to control the display to display the first calibration data in the calibration result interface of the first item, that is, to control the calibration result interface of the first item to display the first calibration data. In this embodiment, by displaying the calibration data on the display interface, it is convenient for operators to view and verify the calibration results.

[0205] In one implementation, the first calibration data is a continuous first calibration curve. The control display shows the first calibration data in the calibration result interface of its first item, including: the control display showing a continuous first calibration curve in the calibration result interface of its first item. The horizontal axis of the first calibration curve is used to characterize the concentration of the target analyte, and the vertical axis is used to characterize at least one of reactivity, absorbance, and scattered light intensity. Reactivity can be calculated using the endpoint method or the fixed-time method. When the reactivity is calculated using the endpoint method, the formula for calculating the reactivity is R = Ai - k * Ab, where R is the reactivity, Ai is the absorbance measured at the reaction time measurement point (i.e., the reaction measurement point, the final measurement point of the sample, or the end of the measurement cycle), Ab is the absorbance measured at the blank time measurement point (i.e., the blank measurement point); k is the volume correction factor, and the value of k varies depending on the different detection parameters. This implementation plan sets the calibration curves obtained by calibrating the same test item using different detection parameters as a continuous curve. This is equivalent to processing the different calibration curves obtained by calibrating the same test item using different detection parameters into a continuous curve for display. In other words, it processes the calibration curves of different concentration ranges into a continuous curve for display. This makes the calibration result interface of the project more concise, allowing operators to quickly and intuitively view all calibration curves obtained by calibrating the same test item using different detection parameters on the same interface. This helps operators to quickly and intuitively obtain the key calibration information of the test item.

[0206] Of course, in specific applications, calibration curves obtained by calibrating the same detection item using different detection parameters can also be displayed separately and independently. For example, as an alternative implementation, the first calibration data includes a second calibration curve and a third calibration curve, which are set alternately. The first calibration data for the first item, obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second and third photometric results, and the concentration of the target analyte in the third calibrator and the fourth photometric result, includes: obtaining the second calibration curve based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result; and obtaining the third calibration curve based on the concentration of the target analyte in the second calibrator and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result. Controlling the display of the first calibration data on the calibration result interface for the first item includes: controlling the display of the second and third calibration curves on the calibration result interface for the first item. One of the second and third calibration curves is used to characterize the calibration curve for the low concentration range, and the other is used to characterize the calibration curve for the high concentration range. In this alternative implementation, different calibration curves obtained by calibrating the same test item using different detection parameters are displayed separately and independently, that is, calibration curves of different concentration ranges are displayed separately and independently, instead of processing the calibration curves of different concentration ranges into a continuous curve.

[0207] In one implementation, the second and third calibration curves are set apart from each other, including one of the following situations: the second and third calibration curves are displayed independently in two different coordinate systems, or the second and third calibration curves are displayed in the same coordinate system and are set apart (i.e., the second and third calibration curves do not intersect or connect in the same coordinate system).

[0208] In one implementation, the sample analyzer 10 also includes a display, which is used to display at least the calibration result details interface for each calibrator used in the first project. The calibration result details interface for each calibrator displays the number of times the sub-calibration process was repeated and the photometric results. The controller 200 is also configured to: in response to a first trigger command, control the display to show the calibration result details interface for the first calibrator, which displays the number of times the first sub-calibration process was executed and the first photometric result; in response to a second trigger command, control the display to show the calibration result details interface for the second calibrator, which displays the number of times the second sub-calibration process was repeated and the second and third photometric results; and in response to a third trigger command, control the display to show the calibration result details interface for the third calibrator, which displays the number of times the third sub-calibration process was repeated and the fourth photometric result. In this embodiment, displaying the number of times the sub-calibration process was repeated and the photometric results for each calibrator on its calibration details interface facilitates better viewing and verification of the calibration results by the operator.

[0209] As one implementation, the calibration result details interface of the first calibrator also displays a reaction curve. The horizontal axis of the reaction curve is used to characterize the measurement period, and the vertical axis is used to characterize the absorbance or scattered light intensity.

[0210] In one implementation, the display is also used to show the calibration result interface of the first project. The calibration result interface of the first project displays at least the first calibration data and information about each calibrator used in the sub-calibration process of the first project. The first trigger instruction includes: an instruction formed by an operator viewing the first calibrator in the calibration result interface of the first project through at least one of screen touch, mouse operation, keyboard operation, and voice input; the second trigger instruction includes: an instruction formed by an operator viewing the second calibrator in the calibration result interface of the first project through at least one of screen touch, mouse operation, keyboard operation, and voice input; the third trigger instruction includes: an instruction formed by an operator viewing the third calibrator in the calibration result interface of the first project through at least one of screen touch, mouse operation, keyboard operation, and voice input. In this implementation, the operator can access the calibration result details interface of a calibrator from the calibration result interface of the project through human-computer interaction to view the calibration information of a specific calibrator; the operation method is simple.

[0211] In the above scheme, the first calibration data is formed by two calibration curves. Of course, in specific applications, the first calibration data can also be formed by three or more calibration curves. For example, as an alternative implementation, the first calibration data includes a second calibration curve, a third calibration curve, and a fourth calibration curve. The controller 200 is also configured to execute the following calibration procedure for the first item: control the sample measurement component 100 to perform the fourth sub-calibration procedure of the first item a fourth time on the fourth calibrator to obtain the seventh and eighth photometric results; control the sample measurement component 100 to perform the fifth sub-calibration procedure of the first item a fifth time on the fifth calibrator to obtain the ninth photometric result. The above-mentioned method for obtaining the first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second and third photometric results, and the concentration of the target analyte in the third calibrator and the fourth photometric result includes: obtaining a second calibration curve based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result; obtaining a third calibration curve based on the concentration of the target analyte in the second calibrator and the third and fourth photometric results, and the concentration of the target analyte in the third calibrator and the seventh photometric result; and obtaining a fourth calibration curve based on the concentration of the target analyte in the fourth calibrator and the eighth and ninth photometric results; wherein the concentration of the target analyte in the fourth calibrator is greater than the concentration of the target analyte in the third calibrator. The second, third, and fourth calibration curves are connected to form a continuous curve, or at least two of the second, third, and fourth calibration curves are spaced apart from each other. In this implementation scheme, the first item can have three different detection parameters. Its calibration curve can be either a single calibration curve composed of three segments or three separate, independently displayed calibration curves. That is, by performing the sub-calibration process using three different detection parameters, a second, third, and fourth calibration curve can be obtained respectively. These three calibration curves can be processed into a continuous calibration curve or displayed separately. The sample analyzer 10 sets three detection parameters for one item, which can further broaden the measurement range. Of course, in specific applications, the first item can also have only two detection parameters, or it can have four or more.

[0212] In one implementation, the aforementioned control sample measurement component 100 performs a first-item sample measurement procedure on the same sample used to detect the target analyte using a first detection parameter and a second detection parameter to obtain sample photometric results. Based on the sample photometric results and first calibration data, a detection result of the concentration of the target analyte in the sample is obtained. This includes: the control sample measurement component 100 performs a first-item sample measurement procedure on the same sample used to detect the target analyte using a first detection parameter and a second detection parameter to obtain a fifth photometric result corresponding to the first detection parameter and a sixth photometric result corresponding to the second detection parameter; based on the fifth photometric result and the first calibration data, first measurement data is obtained; based on the sixth photometric result and the first calibration data, second measurement data is obtained; and based on the first measurement data and the second measurement data, a detection result of the concentration of the target analyte in the sample is obtained. In this embodiment, in the sample measurement, two sets of different measurement data are obtained using different detection parameters, and the sample measurement data are calibrated using different segments of calibration data (e.g., calibration curves). Then, the detection result of the concentration of the target analyte in the sample is obtained by comparing it with a threshold.

[0213] In one embodiment, the sample dispensing component 110 includes a sample needle, a first suction and discharge power source for driving the suction and discharge action of the sample needle, and a first motion drive mechanism for driving the sample needle to perform spatial movement.

[0214] In one embodiment, the reagent dispensing component 120 includes a reagent needle, a second suction / dispensing power source for driving the reagent needle's suction / dispensing action, and a second motion drive mechanism for driving the reagent needle to perform spatial movement.

[0215] In one embodiment, the sample determination assembly 100 further includes a reagent storage component 150 for storing reagent containers, and a reagent dispensing component 120 for drawing reagents from the reagent containers on the reagent storage component 150 and dispensing them into the reaction vessel 20.

[0216] In one embodiment, the reagent storage component 150 is disc-shaped, that is, the reagent storage component 150 is a reagent tray. Of course, in specific applications, the reagent storage component 150 can also be other shapes.

[0217] In one embodiment, the sample determination assembly 100 further includes a reaction carrier 140, which is used to carry the reaction container 20 for the reaction of the sample and reagents inside the reaction container 20, and to carry the reaction container 20 for the reaction of the calibrator and reagents inside the reaction container 20.

[0218] In one embodiment, the reaction support member 140 is disc-shaped, that is, the reaction support member 140 is a reaction disk. Of course, in specific applications, the reaction support member 140 can also be other shapes.

[0219] In one implementation, the reaction support component 140 can drive the reaction container 20 thereon to rotate, thereby driving the reaction container 20 to move to different work positions.

[0220] In one embodiment, the photometric component 130 is used to perform optical measurements on the reaction liquid inside the reaction vessel 20 on the reaction support component 140.

[0221] In one embodiment, the reagent dispensing component 120 is used to draw reagents from the reagent container on the reagent storage component 150 and dispense them into the reaction vessel 20 located on the reaction support component 140.

[0222] In one embodiment, the sample dispensing component 110 is used to draw samples from the sample container and dispense them into the reaction container 20 located on the reaction support component 140, and to draw calibrators from the calibrator container and dispense them into the reaction container 20 located on the reaction support component 140.

[0223] In one embodiment, the sample determination assembly 100 further includes a sample injection component 160 for placing a sample container containing a sample to load the sample. A sample dispensing component 110 is used to aspirate a sample from the sample container located in the sample injection component 160 and dispense it into the reaction vessel 20 located on the reaction support component 140.

[0224] In one embodiment, the sample analyzer 10 also includes a cleaning component (not shown) for cleaning the reaction vessel 20 after a calibration procedure or a sample determination procedure has been completed. In this embodiment, the reaction vessel 20 is a container that can be recycled after cleaning. The first reaction vessel, the second reaction vessel, and the fourth reaction vessel can be different reaction vessels or the same reaction vessel.

[0225] In one implementation, the sample analyzer 10 is a biochemical analyzer, which can be used to detect biochemical items in samples. Of course, in specific applications, the sample analyzer 10 can also be other types of analyzers, such as an immunoassay analyzer.

[0226] Specifically, to obtain a wider measurement range, during the establishment of multiple calibration curves with multiple detection parameters (multiple photometric components 130 and / or multiple reagents and / or multiple reaction systems and / or multiple wavelengths), a concentration overlap region (including the intersection point and region) is required between every two calibration curves. Within this concentration overlap region, one or more calibrators are needed to ensure accuracy within the measured concentration range. For one or more calibrators in the concentration overlap region, repeated calibration tests are combined according to the number of calibration repetitions for each calibrator during the calibration test, thereby reducing the number of repeated calibrations for each calibrator, which improves calibration efficiency and reduces calibrator consumption.

[0227] To better illustrate the scheme of this embodiment, the following example uses FER (Ferritin) detection as the first item for further explanation:

[0228] Example (1):

[0229] A method for measuring FER combining scattering and transmission is provided. The method includes: Method A, measuring scattered light at a wavelength of 800 nm using a scattering light measuring component 130, using a first reagent R1 and a second reagent R2, with a blank time set to 14 s-16 s, a reaction time set to 31 s-33 s, and a calibration repetition number (the number of times each calibrator repeats the sub-calibration process) of 3 times; Method B, measuring transmitted light at a primary wavelength of 570 nm and a secondary wavelength of 800 nm using a transmission light measuring component 130, using a first reagent R1 and a second reagent R2, with a blank time set to 14 s-16 s, a reaction time set to 31 s-33 s, and a calibration repetition number of 3 times.

[0230] The concentration level of the target analyte in the calibrator used in Method A is less than or equal to the concentration level of the target analyte in the calibrator used in Method B, and both methods share calibrator No. 5. Although both Method A and Method B require three repetitions for the shared calibrator No. 5, the number of calibration repetitions can be combined because the amounts of calibrator and reagents used in the testing processes of Method A and Method B are the same. Example (I) shows a combined number of repetitions of three, meaning that the second sub-calibration procedure only needs to be repeated three times for calibrator No. 5.

[0231] The relevant parameters in Example (1) are shown in Tables 1, 2, and 3 below:

[0232] Table 1

[0233] Calibration quantity R1 reagent quantity R2 reagent amount Method A 2mL 150mL 30mL Method B 2mL 150mL 30mL

[0234] Table 2

[0235]

[0236] Table 3

[0237]

[0238] Note: √ indicates the selected calibrator, () indicates the calibration target value of this method, and / indicates that the calibrator is not selected.

[0239] Example (2):

[0240] A method for measuring FER combining scattering and transmission is provided. The method includes: Method A, measuring scattered light at a wavelength of 800 nm using a scattering light measuring component 130, using a first reagent R1 and a second reagent R2, with a blank time set to 14 s-16 s, a reaction time set to 31 s-33 s, and a calibration repetition count of 3 times; Method B, measuring transmitted light at a dominant wavelength of 570 nm and a secondary wavelength of 800 nm using a transmission light measuring component 130, using a first reagent R1 and a second reagent R2, with a blank time set to 14 s-16 s, a reaction time set to 31 s-33 s, and a calibration repetition count of 3 times.

[0241] The concentration of the target analyte in the calibrator used in Method A is less than or equal to the concentration of the target analyte in the calibrator used in Method B, and both methods share calibrator No. 5. Although both Method A and Method B require three repetitions for the shared calibrator No. 5, the number of calibration repetitions can be combined because the amounts of calibrator and reagents used in the testing processes of Method A and Method B are the same. Example (II) shows a combined number of five repetitions, meaning that the second sub-calibration procedure only needs to be repeated five times for calibrator No. 5.

[0242] The relevant parameters in Example (II) are shown in Tables 4, 5, and 6 below:

[0243] Table 4

[0244] Calibration quantity R1 reagent quantity R2 reagent amount Method A 2mL 150mL 30mL Method B 2mL 150mL 30mL

[0245] Table 5

[0246]

[0247] Table 6

[0248]

[0249] Note: √ indicates the selected calibrator, () indicates the calibration target value of this method, and / indicates that the calibrator is not selected.

[0250] Example (3):

[0251] A method for measuring FER using a multi-wavelength transmission light measurement component 130 is provided. The method includes: Method A, measuring transmitted light at a wavelength of 340 nm using the transmission light measurement component 130, using a first reagent R1 and a second reagent R2, with a blank time set to 14 s-16 s, a reaction time set to 31 s-33 s, and a calibration repetition count of 3 times; Method B, measuring transmitted light at a wavelength of 570 nm using the transmission light measurement component 130, using a first reagent R1 and a second reagent R2, with a blank time set to 14 s-16 s, a reaction time set to 31 s-33 s, and a calibration repetition count of 3 times.

[0252] The concentration of the target analyte in the calibrator used in Method A is less than or equal to the concentration of the target analyte in the calibrator used in Method B. Both methods share calibrator #1 and calibrator #5. Although both Method A and Method B require three repetitions for sharing calibrator #1 and calibrator #5, the number of calibration repetitions can be combined because the amounts of calibrator and reagents used in the testing processes of Method A and Method B are the same. Example (III) shows a combined number of repetitions of 3, meaning that both calibrator #1 and calibrator #5 only need to be repeated three times in the sub-calibration process.

[0253] The relevant parameters in Example (III) are shown in Tables 7, 8, and 9 below:

[0254] Table 7

[0255] Calibration quantity R1 reagent quantity R2 reagent amount Method A 2mL 150mL 30mL Method B 2mL 150mL 30mL

[0256] Table 8

[0257]

[0258] Table 9

[0259]

[0260] Note: √ indicates the selected calibrator, () indicates the calibration target value of this method, and / indicates that the calibrator is not selected.

[0261] This embodiment addresses the problem of efficiently and resource-efficiently utilizing multiple calibrators to establish multiple calibration curves when multiple detection parameters and calibrators are present. Specifically, to obtain a wider measurement range, during the establishment of multiple calibration curves for multiple detection parameters (e.g., multiple photometric components 130, multiple reagents, multiple wavelengths, multiple reaction times, multiple blank times, etc.), a concentration overlap region (including intersection points and regions) is required between the calibrator concentration ranges corresponding to every two calibration curves. Within this concentration overlap region, one or more calibrators are needed to ensure accuracy within the measurement concentration range. For one or more calibrators in the concentration overlap region, the number of calibration repetitions during the calibration test is reduced to decrease the number of repeated calibration tests for calibrators in the concentration overlap region. That is, the concentration overlap region of two calibration curves outputs the photometric values ​​of two detection parameters in one calibration sub-process, without requiring separate repeated testing for each detection parameter. This helps reduce calibrator waste and allows for the acquisition of two calibration curves with different concentration ranges through a low-cost and efficient calibration method.

[0262] The sample analyzer 10 provided in the second aspect of the present invention includes a sample measurement component 100, a display, and a controller 200. The sample measurement component 100 is used to perform a calibration procedure for a first item on a calibrator containing a target analyte and whose concentration is known; and to perform a sample measurement procedure for a sample used to detect the target analyte. The display is used to display at least the calibration result details interface of each calibrator used in the first item, and the calibration result details interface of each calibrator displays the number of times the sub-calibration procedure is repeated for the calibrator and the photometric results. The controller 200 is configured to: in response to a first trigger command, control the display to show a calibration result details interface for the first calibrator used in the first item, the calibration result details interface for the first calibrator showing the first number of times the sample measurement component 100 repeatedly performs the sub-calibration process of the first item on the first calibrator using the first detection parameters; in response to a second trigger command, control the display to show a calibration result details interface for the second calibrator, the calibration result details interface for the second calibrator showing the second number of times the sample measurement component 100 repeatedly performs the sub-calibration process of the first item on the second calibrator using the first detection parameters and the second detection parameters, and the second and third photometric results obtained based on the second number of times the sample measurement component 100 performs the sub-calibration process of the first item on the second calibrator using the first detection parameters and the second detection parameters; in response to a third trigger command, control the display to show a calibration result details interface for the third calibrator, the calibration result details interface for the third calibrator showing the third number of times the sample measurement component 100 repeatedly performs the sub-calibration process of the first item on the third calibrator using the second detection parameters, and the fourth photometric result obtained based on the third number of times the sample measurement component 100 performs the sub-calibration process of the first item on the third calibrator using the second detection parameters. In this embodiment, the concentration of the target analyte in the second calibrator is greater than that in the first calibrator but less than that in the third calibrator; the first and second detection parameters are different. This implementation allows viewing the number of recalibrations and photometric results (including at least one of reactivity, absorbance, and scattered light intensity) for each calibrator through the calibration result details interface. In this implementation, since the photometric results of the second calibrator include the second and third photometric results obtained by calibrating the second calibrator using the first and second detection parameters respectively, it is equivalent to the first and second detection parameters sharing a portion of the calibrator, thus reducing the number of calibrators required.

[0263] In one implementation, the second number is greater than or equal to the first number, and greater than or equal to the third number, but less than the sum of the first and third numbers. In this implementation, the number of calibration repetitions for different detection parameters sharing the same calibrator is set to be less than the sum of the number of calibration repetitions for each detection parameter individually. This reduces the number of calibration repetitions, thereby improving calibration efficiency and reducing calibrator consumption.

[0264] In one implementation, the first number, the second number, and the third number are all greater than or equal to two; and / or, the first number is equal to the third number.

[0265] In one embodiment, the sample measurement assembly 100 includes a sample dispensing component 110, a reagent dispensing component 120, and an optical measurement component 130. The sample dispensing component 110 is used to add calibrators into the reaction container 20, the reagent dispensing component 120 is used to add reagents into the reaction container 20, and the optical measurement component 130 is used to perform optical measurement on the reaction solution in the reaction container 20, which is at least composed of calibrators and reagents. The different detection parameters mentioned above include any of the following: different components and / or different concentrations of reagents, different optical measurement components 130, different wavelengths of light, different reaction times, and different blank times.

[0266] In one implementation, the controller 200 is further configured to: obtain a second calibration curve for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result; obtain a third calibration curve for the first item based on the concentration of the target analyte in the second calibrator and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result; connect the second calibration curve and the third calibration curve to form a continuous first calibration curve; or, the second calibration curve and the third calibration curve are set alternately.

[0267] Apart from the above, other parts and principles of the sample analyzer 10 provided in the second aspect of the present invention can be referred to the first aspect above, and will not be described in detail here.

[0268] The sample analyzer 10 provided in the third aspect of the present invention includes a sample measurement component 100 and a controller 200. The sample measurement component 100 is used to perform a calibration procedure for a first item on a calibrator containing a target analyte and whose concentration is known; and to perform a sample measurement procedure for a sample used to detect the target analyte. The controller 200 is configured to control the operation of the sample measurement component 100. The sample measurement component 100 includes a sample dispensing component 110 and an optical measurement component 130. The sample dispensing component 110 includes a sample needle for adding the calibrator into a reaction container 20. The optical measurement component 130 is used to perform optical measurement on the reaction solution in the reaction container 20, which is at least composed of the calibrator and reagents. The controller 200 is configured to perform the following calibration procedure for the first item: The controller controls the sample needle to dispense a first calibrator of the same concentration into a first number of reaction containers 20; the controller controls the photometric unit 130 to perform optical measurements on the reaction solution in the first number of reaction containers 20, which is made from at least the first calibrator and reagents, to obtain a first photometric result; The controller controls the sample needle to dispense a second calibrator of the same concentration into a second number of reaction containers 20; the controller controls the photometric unit 130 to perform optical measurements on the reaction solution in the second number of reaction containers 20, which is made from at least the second calibrator and reagents, to obtain a second photometric result and a third photometric result; The controller controls the sample needle to dispense a third calibrator of the same concentration into a third number of reaction containers 20; the controller controls the photometric unit 130 to perform optical measurements on the reaction solution in the third number of reaction containers 20, which is made from at least the third calibrator and reagents, to obtain a fourth photometric result; Based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second and third photometric results, and the concentration of the target analyte in the third calibrator and the fourth photometric result, first calibration data is obtained. The controller 200 is also configured to: control the sample measurement component 100 to perform a first-item sample measurement procedure on the same sample used for detecting the target analyte, obtain sample photometric results, and obtain the detection result of the concentration of the target analyte in the sample (i.e., the detection result of the first item of the sample) based on the sample photometric results and the first calibration data. Wherein, the concentration of the target analyte in the second calibrator is greater than the concentration of the target analyte in the first calibrator and less than the concentration of the target analyte in the third calibrator. The second quantity is greater than or equal to the first quantity, and greater than or equal to the third quantity, and less than the sum of the first and third quantities. In one sampling action, the sample needle completes the action of distributing the calibrator to a reaction vessel 20. The quantity of a certain calibrator distributed to the reaction vessel 20 is equal to the number of repeated sampling actions for that calibrator. In this embodiment, the number of repeated sampling actions for calibration of calibrators shared by different detection parameters is set to be less than the sum of the number of repeated sampling actions for individual detection parameters. This reduces the number of repeated calibration sampling actions, thereby improving calibration efficiency and reducing calibrator consumption.

[0269] In one implementation method, the first quantity, the second quantity, and the third quantity are all greater than or equal to two.

[0270] In one implementation method, the first quantity is equal to the third quantity.

[0271] In one implementation, the first photometric result is obtained by the sample measurement component 100 measuring the first calibrator using the first detection parameter; the second and third photometric results are obtained by the sample measurement component 100 measuring the same second calibrator using the first and second detection parameters, respectively; the fourth photometric result is obtained by the sample measurement component 100 measuring the third calibrator using the second detection parameter; wherein the first and second detection parameters are different detection parameters; the different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components 130, different wavelengths of light, different reaction times, and different blank times.

[0272] Apart from the above, other parts and principles of the sample analyzer 10 provided in the third aspect of the present invention can be referred to the first aspect above, and will not be described in detail here.

[0273] A fourth aspect of the present invention provides a control method for a sample analyzer 10, the control method comprising the following calibration procedure for a first item: controlling a sample measurement component 100 to perform at least one first sub-calibration procedure of the first item on a first calibrator using a first detection parameter to obtain a first photometric result; controlling the sample measurement component 100 to perform at least one second sub-calibration procedure of the first item on a second calibrator using a first detection parameter and a second detection parameter to obtain a second photometric result and a third photometric result, wherein each second sub-calibration procedure of the first item is performed by the sample measurement component 100 on the same second calibrator using the first detection parameter and the second detection parameter; controlling the sample measurement component 100 to perform at least one third sub-calibration procedure of the first item on a third calibrator using a second detection parameter to obtain a fourth photometric result; and obtaining first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second and third photometric results, and the concentration of the target analyte in the third calibrator and the fourth photometric result. The concentration of the target analyte in the second calibrator is greater than that in the first calibrator but less than that in the third calibrator; the first detection parameter and the second detection parameter are different detection parameters.

[0274] As one implementation, the above control method further includes the following sample measurement process for the first item: the control sample measurement component 100 performs the sample measurement process for the first item on the same sample used to detect the target analyte using the first detection parameter and the second detection parameter to obtain the sample photometric result, and obtains the detection result of the concentration of the target analyte in the sample based on the sample photometric result and the first calibration data.

[0275] In one implementation, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameters to obtain a first photometric result. This includes: the control sample measurement component 100 performs a first sub-calibration process of the first item on the first calibrator for a first number of times using the first detection parameters to obtain a first photometric result. The control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameters and the second detection parameters to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration process of the first item on the second calibrator for a second number of times using the first detection parameters and the second detection parameters to obtain a second photometric result and a third photometric result. In each second sub-calibration process of the first item in the second number of times the first item is performed by the sample measurement component 100 on the same second calibrator using the first detection parameters and the second detection parameters. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters to obtain a fourth photometric result. This includes: the control sample measurement component 100 performs a third sub-calibration procedure of the first item on the third calibrator using the second detection parameters to obtain a fourth photometric result. The second result is greater than or equal to the first result, and greater than or equal to the third result, and less than the sum of the first and third results.

[0276] As a first embodiment for obtaining the first photometric result, the second photometric result, the third photometric result, and the fourth photometric result, the control sample measurement component 100 performs a first sub-calibration process of the first item for the first number of times on the first calibrator through the first detection parameter to obtain the first photometric result, including: the control sample measurement component 100 performs a first sub-calibration process of the first item for the first number of times on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value equal to the first number of times, and calculates the average value of the first initial photometric value equal to the first number of times to obtain the first photometric result of the first calibrator of that concentration. The aforementioned control sample measurement component 100 performs a second sub-calibration process on the second calibrator for the second number of the first item using the first detection parameter and the second detection parameter to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration process on the second calibrator of the same concentration for the second number of the first item using the first detection parameter and the second detection parameter to obtain a second initial photometric value and a third initial photometric value equal to the second number of ... third photometric value of the second number of the second number of the third number of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the third number of the second number of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the third number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the second number of the third photometric value of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second number of the second The aforementioned control sample measurement component 100 performs a third sub-calibration process of the first item for the third number of times on the third calibrator using the second detection parameters to obtain a fourth photometric result. This process includes: the control sample measurement component 100 performs a third sub-calibration process of the first item for the third number of times on the third calibrator using the second detection parameters to obtain a fourth initial photometric value equal to the third number of times; and the average value of the fourth initial photometric value equal to the third number of times is calculated to obtain the fourth photometric result of the third calibrator at that concentration.

[0277] In a second implementation of obtaining the first, second, third, and fourth photometric results, the first, second, and third numbers are all odd numbers greater than or equal to three. The control sample measurement component 100 performs a first sub-calibration process of the first item of the first number on the first calibrator using the first detection parameters to obtain the first photometric result. This includes: the control sample measurement component 100 performs a first sub-calibration process of the first item of the first number on the first calibrator of the same concentration using the first detection parameters to obtain a first initial photometric value equal to the first number. The first initial photometric value, which is the middle value among the first initial photometric values ​​equal to the first number, is taken as the first photometric result of the first calibrator of that concentration. The aforementioned control sample measurement component 100 performs a second sub-calibration process on the second calibrator for the second number of first items using the first detection parameter and the second detection parameter to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration process on the second calibrator of the same concentration for the second number of first items using the first detection parameter and the second detection parameter to obtain a second initial photometric value and a third initial photometric value equal to the second number of second initial photometric values. The second initial photometric value, which is the middle value among the second initial photometric values ​​equal to the second number of second initial photometric values, is taken as the second photometric result of the second calibrator of that concentration. The third initial photometric value, which is the middle value among the third initial photometric values ​​equal to the second number of third initial photometric values, is taken as the third photometric result of the second calibrator of that concentration. The aforementioned control sample measurement component 100 performs a third sub-calibration procedure on the third calibrator using the second detection parameters, performing the first item for the third time, to obtain a fourth photometric result. This includes: the control sample measurement component 100 performs a third sub-calibration procedure on the third calibrator of the same concentration using the second detection parameters, obtaining a fourth initial photometric value equal to the third number of times. The fourth initial photometric value, which is the middle value among the fourth initial photometric values ​​equal to the third number of times, is taken as the fourth photometric result for that concentration of the third calibrator. The first, second, and third times can be, for example, three, five, or seven times, etc.

[0278] As a third implementation method for obtaining the first photometric result, the second photometric result, the third photometric result, and the fourth photometric result, the first number, the second number, and the third number are all greater than or equal to four. The control sample measurement component 100 performs a first sub-calibration process of the first item of the first number on the first calibrator through the first detection parameter to obtain the first photometric result. This includes: the control sample measurement component 100 performs a first sub-calibration process of the first item of the first number on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value with a quantity equal to the first number; and averages the remaining first initial photometric values ​​(excluding the maximum and minimum values) among the first initial photometric values ​​with a quantity equal to the first number to obtain the first photometric result of the first calibrator of that concentration. The aforementioned control sample measurement component 100 performs a second sub-calibration process on the second calibrator using a second number of first items with a first detection parameter and a second detection parameter to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration process on the second calibrator of the same concentration using a second number of first items with a first detection parameter and a second number of third initial photometric values ​​equal to the second number; the average value of the remaining second initial photometric values ​​(excluding the maximum and minimum values) equal to the second number is calculated to obtain the second photometric result of the second calibrator at that concentration; and the average value of the remaining third initial photometric values ​​(excluding the maximum and minimum values) equal to the second number is calculated to obtain the third photometric result of the second calibrator at that concentration. The aforementioned control sample measurement component 100 performs a third sub-calibration process of the first item for the third number of times on the third calibrator using the second detection parameters to obtain a fourth photometric result. This process includes: the control sample measurement component 100 performs a third sub-calibration process of the first item for the third number of times on the third calibrator using the second detection parameters to obtain a fourth initial photometric value equal to the third number of times; and averages the remaining fourth initial photometric values ​​(excluding the maximum and minimum values) among the fourth initial photometric values ​​equal to the third number of times to obtain the fourth photometric result of the third calibrator at that concentration.

[0279] In one implementation, the control sample measurement component 100 performs at least one first sub-calibration procedure of the first item on the first calibrator using the first detection parameters to obtain a first photometric result. This includes: the control sample measurement component 100 performs a first sub-calibration procedure of the first item for at least two first calibrators with different concentrations using the first detection parameters to obtain at least two first photometric results corresponding one-to-one with the at least two first calibrators. The control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameters and the second detection parameters to obtain a second photometric result and a third photometric result. This includes: the control sample measurement component 100 performs a second sub-calibration procedure of the first item for at least one second calibrator to obtain at least one second photometric result corresponding one-to-one with the at least one second calibrator and at least one third photometric result corresponding one-to-one with the at least one second calibrator. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters to obtain a fourth photometric result. This includes: the control sample measurement component 100 performs a third sub-calibration procedure of the first item on at least two third calibrators with different concentrations using the second detection parameters to obtain at least two fourth photometric results that correspond one-to-one with at least two third calibrators. The aforementioned method of obtaining first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second and third photometric results, and the concentration of the target analyte in the third calibrator and the fourth photometric result includes: obtaining first calibration data based on the concentration of the target analyte in at least two first calibrators and at least two first photometric results, the concentration of the target analyte in at least one second calibrator and at least one second and at least one third photometric result, and the concentration of the target analyte in at least two third calibrators and at least two fourth photometric results.

[0280] In one implementation, the control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using a first detection parameter and a second detection parameter. This includes performing at least one of the following processes: the control sample measurement component 100 measures the second calibrator dispensed into a second reaction vessel using the first detection parameter to obtain a second initial photometric value; the control sample measurement component 100 measures the second calibrator in the second reaction vessel using the second detection parameter to obtain a third initial photometric value. Obtaining the second photometric result includes obtaining a second photometric result based on the second initial photometric value obtained in the at least one second sub-calibration process of the first item. Obtaining the third photometric result includes obtaining a third photometric result based on the third initial photometric value obtained in the at least one second sub-calibration process of the first item.

[0281] In one implementation, the control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using a first detection parameter and a second detection parameter, including: performing at least two of the following processes: the control sample measurement component 100 measures the second calibrator dispensed into a second reaction vessel using the first detection parameter to obtain a second initial photometric value; the control sample measurement component 100 measures the second calibrator in the second reaction vessel using the second detection parameter to obtain a third initial photometric value. Obtaining the second photometric result includes: obtaining a second photometric result based on the second initial photometric value obtained in at least two second sub-calibration processes of the first item. Obtaining the third photometric result includes: obtaining a third photometric result based on the third initial photometric value obtained in at least two second sub-calibration processes of the first item.

[0282] As one implementation method, the different detection parameters mentioned above include any of the following: different components and / or different concentrations of reagents, different photometric components 130, different wavelengths of light, different reaction times, and different blank times.

[0283] When the aforementioned different detection parameters include reagents with different components and / or different concentrations, the aforementioned control sample measurement component 100 performs at least one first sub-calibration procedure for the first item on the first calibrator using the first detection parameters, including: performing at least one of the following procedures: controlling the reagent dispensing component 120 to add the first reagent into the first reaction container; controlling the sample dispensing component 110 to add the first calibrator into the first reaction container; controlling the photometric component 130 to perform optical measurement on the first reaction solution in the first reaction container, which is at least composed of the first calibrator and the first reagent, to obtain a first initial photometric value. Obtaining the first photometric result includes: obtaining the first photometric result based on the first initial photometric value obtained in the aforementioned at least one first sub-calibration procedure for the first item. The aforementioned control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following procedures: the control reagent dispensing component 120 adds the first reagent into the second reaction container; the control sample dispensing component 110 adds the second calibrator into the second reaction container; the control photometry component 130 performs optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain a second initial photometry value; the control reagent dispensing component 120 adds the second reagent into the second reaction container; the control photometry component 130 performs optical measurement on the third reaction liquid in the second reaction container, which is at least composed of the second calibrator, the first reagent, and the second reagent, to obtain a third initial photometry value. Obtaining the second photometry result includes obtaining the second photometry result based on the second initial photometry value obtained in the aforementioned at least one second sub-calibration procedure of the first item. Obtaining the third photometry result includes obtaining the third photometry result based on the third initial photometry value obtained in the aforementioned at least one second sub-calibration procedure of the first item. In performing a second sub-calibration procedure, the first reagent, the second calibrator, and the second reagent are sequentially dispensed into the same second reaction vessel, and different reaction solutions within the same second reaction vessel are measured to obtain a second initial photometric value and a third initial photometric value. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following procedures: the control reagent dispensing component 120 adds the first reagent into the fourth reaction vessel; the control sample dispensing component 110 adds the third calibrator into the fourth reaction vessel; the control reagent dispensing component 120 adds the second reagent into the fourth reaction vessel; and the control photometric component 130 performs optical measurement on the fourth reaction solution in the fourth reaction vessel, which is at least composed of the third calibrator, the first reagent, and the second reagent, to obtain a fourth initial photometric value. Obtaining the fourth photometric result includes obtaining the fourth photometric result based on the fourth initial photometric value obtained in the aforementioned at least one third sub-calibration procedure of the first item. The first reagent and the second reagent differ in at least one of the following aspects: composition and concentration.

[0284] When the different detection parameters mentioned above include different photometric components 130, the sample measurement assembly 100 includes a first photometric component 131 and a second photometric component 132. The aforementioned control of the sample measurement assembly 100 to perform at least one first sub-calibration process of a first item on the first calibrator using the first detection parameters includes: performing at least one of the following processes: controlling the first photometric component 131 to perform optical measurements on the reaction liquid in the first reaction vessel, which is at least composed of the first calibrator and reagents, to obtain a first initial photometric value. Obtaining the first photometric result includes: obtaining the first photometric result based on the first initial photometric value obtained in the aforementioned at least one first sub-calibration process of the first item. The aforementioned control of the sample measurement assembly 100 to perform at least one second sub-calibration process of a first item on the second calibrator using the first and second detection parameters includes: performing at least one of the following processes: controlling the first photometric component 131 to perform optical measurements on the reaction liquid in the second reaction vessel, which is at least composed of the second calibrator and reagents, to obtain a second initial photometric value; controlling the second photometric component 132 to perform optical measurements on the reaction liquid in the second reaction vessel, which is at least composed of the second calibrator and reagents, to obtain a third initial photometric value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the second sub-calibration process of the first item at least once. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once. In performing one second sub-calibration process, the second calibrator and reagent need to be sequentially dispensed into the same second reaction vessel, and the first photometric component 131 and the second photometric component 132 need to measure the reaction liquid in the same second reaction vessel to obtain the second initial photometric value and the third initial photometric value, respectively. The control sample measurement component 100 performs at least one third sub-calibration process of the first item on the third calibrator through the second detection parameters, including: performing at least one of the following processes: controlling the second photometric component 132 to perform optical measurement on the reaction liquid in the fourth reaction vessel made of at least the third calibrator and reagent to obtain the fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the third sub-calibration process of the first item at least once. Among them, one of the first optical measurement component 131 and the second optical measurement component 132 is a transmission light detector and the other is a scattering light detector.

[0285] When the aforementioned different detection parameters include reagents with different components and / or different concentrations and different photometric components 130, the sample measurement assembly 100 includes a first photometric component 131 and a second photometric component 132. The aforementioned control of the sample measurement assembly 100 to perform at least one first sub-calibration procedure of the first item on the first calibrator using the first detection parameters includes: performing at least one of the following procedures: controlling the reagent dispensing component 120 to add the first reagent into the first reaction container; controlling the sample dispensing component 110 to add the first calibrator into the first reaction container; controlling the first photometric component 131 to perform optical measurement on the first reaction solution in the first reaction container, which is at least composed of the first calibrator and the first reagent, to obtain a first initial photometric value. Obtaining the first photometric result includes: obtaining the first photometric result based on the first initial photometric value obtained in the aforementioned at least one first sub-calibration procedure of the first item. The aforementioned control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following procedures: controlling the reagent dispensing component 120 to add the first reagent into the second reaction container; controlling the sample dispensing component 110 to add the second calibrator into the second reaction container; controlling the first photometric component 131 to perform optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain a second initial photometric value; controlling the reagent dispensing component 120 to add the second reagent into the second reaction container; controlling the second photometric component 132 to perform optical measurement on the third reaction liquid in the second reaction container, which is at least composed of the second calibrator, the first reagent, and the second reagent, to obtain a third initial photometric value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the aforementioned at least one second sub-calibration procedure of the first item. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the aforementioned at least one second sub-calibration procedure of the first item. In performing a second sub-calibration procedure, the first reagent, the second calibrator, and the second reagent need to be sequentially dispensed into the same second reaction container. The first photometric component 131 and the second photometric component 132 need to measure the different reaction solutions within the same second reaction container to obtain a second initial photometric value and a third initial photometric value. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure for the third calibrator using the second detection parameters, including: performing at least one of the following procedures: the control reagent dispensing component 120 adds the first reagent into the fourth reaction container; the control sample dispensing component 110 adds the third calibrator into the fourth reaction container; the control reagent dispensing component 120 adds the second reagent into the fourth reaction container; and the control second photometric component 132 performs optical measurements on the fourth reaction solution within the fourth reaction container, which is at least composed of the third calibrator, the first reagent, and the second reagent, to obtain a fourth initial photometric value.The above-mentioned fourth photometric result is obtained by: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the third sub-calibration process of the first item at least once. The first reagent and the second reagent differ in at least one of the following aspects: composition, concentration; one of the first photometric component 131 and the second photometric component 132 is a transmission light detector, and the other is a scattering light detector.

[0286] When the aforementioned different detection parameters include light of different wavelengths, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameter, including: performing the following process for the first time: controlling the photometry component 130 to perform optical measurement of light of the first wavelength on the reaction liquid in the first reaction vessel, which is made of at least the first calibrator and reagents, to obtain a first initial photometry value. Obtaining the first photometry result includes: obtaining the first photometry result based on the first initial photometry value obtained in the first sub-calibration process of the first item. The control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement of light of the first wavelength on the reaction liquid in the second reaction vessel, which is made of at least the second calibrator and reagents, to obtain a second initial photometry value; controlling the photometry component 130 to perform optical measurement of light of the second wavelength on the reaction liquid in the second reaction vessel, which is made of at least the second calibrator and reagents, to obtain a third initial photometry value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the second sub-calibration process of the first item at least once. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once. The control sample measurement component 100 performs at least one third sub-calibration process of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following processes: controlling the photometric component 130 to perform optical measurement of light of a second wavelength on the reaction liquid in the fourth reaction vessel, which is made of at least the third calibrator and reagents, to obtain a fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the third sub-calibration process of the first item at least once. Wherein, the second wavelength is greater than or less than the first wavelength.

[0287] When the aforementioned different detection parameters include different reaction times, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement on the reaction liquid in the first reaction vessel prepared by at least the first calibrator and reagent under the first reaction time, to obtain a first initial photometry value. Obtaining the first photometry result includes: obtaining the first photometry result based on the first initial photometry value obtained in the aforementioned at least one first sub-calibration process of the first item. The control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement on the reaction liquid in the second reaction vessel prepared by at least the second calibrator and reagent under the first reaction time, to obtain a second initial photometry value; controlling the photometry component 130 to perform optical measurement on the reaction liquid in the second reaction vessel prepared by at least the second calibrator and reagent under the second reaction time, to obtain a third initial photometry value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the second sub-calibration process of the first item at least once. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once. The control sample measurement component 100 performs at least one third sub-calibration process of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following processes: controlling the photometric component 130 to perform optical measurement on the reaction solution prepared in the fourth reaction vessel by at least the third calibrator and reagent under the second reaction time, to obtain a fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the third sub-calibration process of the first item at least once. Wherein, the second reaction time is greater than or less than the first reaction time.

[0288] When the different detection parameters include different blank durations, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared by at least the first calibrator and reagent in the first reaction vessel under the first blank duration, to obtain a first initial photometry value. Obtaining the first photometry result includes: obtaining the first photometry result based on the first initial photometry value obtained in the first sub-calibration process of the first item. The control sample measurement component 100 performs at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter, including: performing at least one of the following processes: controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared by at least the second calibrator and reagent in the second reaction vessel under the first blank duration, to obtain a second initial photometry value; controlling the photometry component 130 to perform optical measurement on the reaction liquid prepared by at least the second calibrator and reagent in the second reaction vessel under the second blank duration, to obtain a third initial photometry value. Obtaining the second photometric result includes: obtaining the second photometric result based on the second initial photometric value obtained in the second sub-calibration process of the first item at least once. Obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once. The control sample measurement component 100 performs at least one third sub-calibration process of the first item on the third calibrator using the second detection parameters, including: performing at least one of the following processes: controlling the photometric component 130 to perform optical measurement on the reaction solution prepared in the fourth reaction vessel by at least the third calibrator and reagent under a second blank time, and obtaining a fourth initial photometric value. Obtaining the fourth photometric result includes: obtaining the fourth photometric result based on the fourth initial photometric value obtained in the third sub-calibration process of the first item at least once. Wherein, the second blank time is greater than or less than the first blank time.

[0289] In one implementation, the control sample measurement component 100 performs at least one first sub-calibration process of the first item on the first calibrator using the first detection parameters to obtain the first photometric result, including: controlling the sample needle to distribute the first calibrator of the same concentration into a first number of reaction containers 20 respectively; controlling the photometric component 130 to perform optical measurements on the reaction liquid made of at least the first calibrator and reagent in the first number of reaction containers 20 respectively to obtain a first number of first initial photometric values; and obtaining the first photometric result based on the first number of first initial photometric values. The aforementioned control sample measurement component 100 performs at least one second sub-calibration procedure of the first item on the second calibrator using the first detection parameter and the second detection parameter to obtain a second photometric result and a third photometric result. This includes: controlling the sample needle to dispense the second calibrator of the same concentration into a second number of reaction containers 20; controlling the photometric component 130 to perform optical measurements on the reaction solution in the second number of reaction containers 20, which is at least composed of the second calibrator and reagents, to obtain a second number of second initial photometric values ​​and a third number of third initial photometric values; obtaining a second photometric result based on the second number of second initial photometric values; and obtaining a third photometric result based on the second number of third initial photometric values. Furthermore, the photometric component 130 obtains both a second initial photometric value and a third initial photometric value for each reaction solution in the second number of reaction containers 20, which is at least composed of the second calibrator and reagents. The aforementioned control sample measurement component 100 performs at least one third sub-calibration procedure of the first item on the third calibrator using the second detection parameters to obtain a fourth photometric result. This includes: controlling the sample needle to dispense the third calibrator of the same concentration into a third number of reaction containers 20; controlling the photometric component 130 to perform optical measurements on the reaction solution in the third number of reaction containers 20, which is composed of at least the calibrator and reagents, to obtain a third number of fourth initial photometric values; and obtaining a fourth photometric result based on the third number of fourth initial photometric values. The second number is greater than or equal to the first number, and greater than or equal to the third number, and less than the sum of the first and third numbers.

[0290] In addition to the above, other parts and principles of the control method of the sample analyzer 10 provided in the fourth aspect of the present invention can refer to the control scheme and principle of the controller 200 in the first aspect above, and will not be described in detail here.

[0291] A fifth aspect of this invention provides a computer-readable storage medium storing a computer program. When the computer program is executed by a processor (e.g., the controller 200 described above), it causes the processor to implement the steps of the control method for the sample analyzer 10 provided in the fourth aspect. The computer-readable storage medium can be an internal storage unit of the sample analyzer 10, such as a hard disk or memory of the sample analyzer 10; or it can be an external storage device of the sample analyzer 10, such as a pluggable hard disk, smart media card (SMC), secure digital (SD) card, flash card, etc., equipped on the sample analyzer 10.

[0292] The above description is merely a preferred embodiment of the present invention and does not limit the patent scope of the present invention. Any equivalent structural transformations made using the contents of the present invention's specification and drawings under the inventive concept of the present invention, or direct / indirect applications in other related technical fields, are included within the patent protection scope of the present invention.

Claims

1. A sample analyzer, characterized in that: include: A sample measurement assembly for performing a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte is known. And a sample measurement procedure for performing the first item on a sample used to detect the target analyte; The controller is configured to perform the following calibration procedure for the first item: The sample measurement component is controlled to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters to obtain the first photometric result; The sample measurement component is controlled to perform the second sub-calibration process of the first item at least once on the second calibrator through the first detection parameter and the second detection parameter to obtain the second optical measurement result and the third optical measurement result. Each time the second sub-calibration process of the first item is performed by the sample measurement component on the same second calibrator through the first detection parameter and the second detection parameter. The sample measurement component is controlled to perform the third sub-calibration process of the first item at least once on the third calibrator using the second detection parameters to obtain the fourth photometric result; The first calibration data for the first item is obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the same second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result. The controller is further configured to: control the sample measurement component to perform the sample measurement process of the first item on the same sample used to detect the target analyte using the first detection parameter and the second detection parameter, to obtain the sample photometric result, and to obtain the detection result of the concentration of the target analyte in the sample based on the sample photometric result and the first calibration data; Wherein, the concentration of the target analyte in the second calibrator is greater than the concentration of the target analyte in the first calibrator, but less than the concentration of the target analyte in the third calibrator; The first detection parameter and the second detection parameter are different detection parameters.

2. The sample analyzer as described in claim 1, characterized in that: The method of controlling the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item on the first calibrator for the first time through the first detection parameter to obtain the first photometric result; The method of controlling the sample measurement component to perform at least one second sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter to obtain a second optical measurement result and a third optical measurement result includes: controlling the sample measurement component to perform a second number of the second sub-calibration processes of the first item on the second calibrator using the first detection parameter and the second detection parameter to obtain a second optical measurement result and the third optical measurement result, wherein in each of the second sub-calibration processes of the first item in the second number of the first item, the second sub-calibration process of the first item is performed by the sample measurement component on the same second calibrator using the first detection parameter and the second detection parameter. The method of controlling the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item a third time on the third calibrator through the second detection parameter to obtain the fourth photometric result; Wherein, the second number is greater than or equal to the first number, and greater than or equal to the third number, and less than the sum of the first number and the third number.

3. The sample analyzer as described in claim 2, characterized in that: The first number, the second number, and the third number are all greater than or equal to two; And / or, the first number is equal to the third number.

4. The sample analyzer as described in claim 3, characterized in that: The method of controlling the sample measurement component to perform the first sub-calibration process of the first item for the first number of times on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item for the first number of times on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value equal to the first number of times, and averaging the first initial photometric value equal to the first number of times to obtain the first photometric result of the first calibrator of that concentration; The method of controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator using the first detection parameter and the second detection parameter to obtain the second photometric result and the third photometric result includes: controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator of the same concentration using the first detection parameter and the second detection parameter to obtain a second initial photometric value and a third initial photometric value equal to the second number of times; averaging the second initial photometric value equal to the second number of times to obtain the second photometric result of the second calibrator of that concentration; and averaging the third initial photometric value equal to the second number of times to obtain the third photometric result of the second calibrator of that concentration. The method of controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator of the same concentration through the second detection parameter to obtain a fourth initial photometric value equal to the third number of times; averaging the fourth initial photometric value equal to the third number of times to obtain the fourth photometric result of the third calibrator of that concentration; Alternatively, the first number, the second number, and the third number are all odd numbers greater than or equal to three. The step of controlling the sample measurement component to perform the first sub-calibration process of the first item of the first number of times on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item of the first number of times on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value with a quantity equal to the first number of times, and taking the first initial photometric value with the middle value among the first initial photometric values ​​with a quantity equal to the first number of times as the first photometric result of the first calibrator of that concentration; The method of controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator using the first detection parameter and the second detection parameter to obtain the second photometric result and the third photometric result includes: controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator of the same concentration using the first detection parameter and the second detection parameter to obtain a second initial photometric value equal to the second number of times and a third initial photometric value equal to the second number of times; taking the second initial photometric value with the middle value among the second initial photometric values ​​equal to the second number of times as the second photometric result of the second calibrator of that concentration; and taking the third initial photometric value with the middle value among the third initial photometric values ​​equal to the second number of times as the third photometric result of the second calibrator of that concentration. The method of controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator of the same concentration through the second detection parameter to obtain a fourth initial photometric value equal to the third number of times; and taking the fourth initial photometric value, which is the middle value among the fourth initial photometric values ​​equal to the third number of times, as the fourth photometric result of the third calibrator of that concentration. Alternatively, if the first number, the second number, and the third number are all greater than or equal to four, the step of controlling the sample measurement component to perform the first sub-calibration process of the first item of the first number of times on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item of the first number of times on the first calibrator of the same concentration through the first detection parameter to obtain a first initial photometric value equal to the first number of times; averaging the remaining first initial photometric values ​​(excluding the maximum and minimum values) among the first initial photometric values ​​equal to the first number of times to obtain the first photometric result of the first calibrator of that concentration. The method of controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator using the first detection parameter and the second detection parameter to obtain the second photometric result and the third photometric result includes: controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on the second calibrator of the same concentration using the first detection parameter and the second detection parameter to obtain a second initial photometric value equal to the second number of times and a third initial photometric value equal to the second number of times; averaging the remaining second initial photometric values ​​(excluding the maximum and minimum values) among the remaining second initial photometric values ​​(excluding the maximum and minimum values) to obtain the second photometric result of the second calibrator of that concentration; and averaging the remaining third initial photometric values ​​(excluding the maximum and minimum values) among the remaining third initial photometric values ​​(excluding the maximum and minimum values) to obtain the third photometric result of the second calibrator of that concentration. The method of controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item for the third number of times on the third calibrator of the same concentration through the second detection parameter to obtain a fourth initial photometric value equal to the third number of times; averaging the remaining fourth initial photometric values ​​(excluding the maximum and minimum values) among the fourth initial photometric values ​​equal to the third number of times to obtain the fourth photometric result of the third calibrator of that concentration.

5. The sample analyzer according to any one of claims 1 to 4, characterized in that: The method of controlling the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample measurement component to perform the first sub-calibration process of the first item for at least two first calibrators with different concentrations for the first time on the first calibrator through the first detection parameter to obtain at least two first photometric results that correspond one-to-one with the at least two first calibrators. The method of controlling the sample measurement component to perform the second sub-calibration process of the first item at least once on the second calibrator through the first detection parameter and the second detection parameter to obtain the second photometric result and the third photometric result includes: controlling the sample measurement component to perform the second sub-calibration process of the first item a second time on at least one second calibrator to obtain at least one second photometric result corresponding to the at least one second calibrator and at least one third photometric result corresponding to the at least one second calibrator; The method of controlling the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample measurement component to perform the third sub-calibration process of the first item a third time on at least two third calibrators with different concentrations respectively through the second detection parameter to obtain at least two fourth photometric results that correspond one-to-one with the at least two third calibrators; The step of obtaining first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result includes: obtaining the first calibration data based on the concentration of the target analyte in at least two first calibrators and the at least two first photometric results, the concentration of the target analyte in at least one second calibrator and the at least one second photometric result and the at least one third photometric result, and the concentration of the target analyte in at least two third calibrators and the at least two fourth photometric results.

6. The sample analyzer as described in claim 1, characterized in that: The method of controlling the sample measurement component to perform a second sub-calibration process of the first item at least once on the second calibrator using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the sample measurement component to measure the second calibrator allocated to a reaction vessel using the first detection parameter to obtain a second initial photometric value; controlling the sample measurement component to measure the second calibrator in the reaction vessel using the second detection parameter or controlling the sample measurement component to measure the second calibrator transferred from the reaction vessel to another reaction vessel using the second detection parameter to obtain a third initial photometric value; Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once; The process of obtaining the third photometric result includes: obtaining the third photometric result based on the third initial photometric value obtained in the second sub-calibration process of the first item at least once.

7. The sample analyzer as described in any one of claims 1 to 4 or 6, characterized in that: The sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component is used to add the calibrator into the reaction container, the reagent dispensing component is used to add the reagent into the reaction container, and the optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least the calibrator and the reagent. The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

8. The sample analyzer as described in claim 7, characterized in that: When the different detection parameters include reagents with different components and / or different concentrations, the control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters includes: performing the following process at least once: controlling the reagent dispensing component to add the first reagent into the first reaction container; controlling the sample dispensing component to add the first calibrator into the first reaction container; controlling the photometric component to perform optical measurement on the first reaction solution in the first reaction container, which is at least made of the first calibrator and the first reagent, to obtain the first initial photometric value; The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once; The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the reagent dispensing component to add the first reagent into the second reaction container; controlling the sample dispensing component to add the second calibrator into the second reaction container; controlling the photometric component to perform optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain the second initial photometric value; controlling the reagent dispensing component to add the second reagent into the second reaction container or controlling the reagent dispensing component to add the second reagent into a third reaction container independent of the second reaction container; controlling the photometric component to perform optical measurement on the third reaction liquid in the second reaction container, which is at least composed of the second reagent and the second reaction liquid, or controlling the photometric component to perform optical measurement on the third reaction liquid in the third reaction container, which is at least composed of the second reagent and the second reaction liquid transferred from the second reaction container to the third reaction container, to obtain the third initial photometric value; Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once; The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once; The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator using the second detection parameter includes: performing the following process at least once: controlling the reagent dispensing component to add the first reagent into the fourth reaction container; controlling the sample dispensing component to add the third calibrator into the fourth reaction container; controlling the reagent dispensing component to add the second reagent into the fourth reaction container; controlling the photometric component to perform optical measurement on the fourth reaction solution in the fourth reaction container, which is at least made of the third calibrator, the first reagent, and the second reagent, to obtain the fourth initial photometric value; The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once; The first reagent and the second reagent differ in at least one of the following aspects: composition and concentration; Alternatively, when the different detection parameters include different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component; The control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter includes: performing the following process at least once: controlling the first photometric component to perform optical measurement on the reaction liquid in the first reaction container made of at least the first calibrator and reagent to obtain the first initial photometric value; The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once; The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least one of the following processes: controlling the first photometric component to perform optical measurement on the reaction liquid in the second reaction container, which is made of at least the second calibrator and the reagent, to obtain the second initial photometric value; controlling the second photometric component to perform optical measurement on the reaction liquid in the second reaction container, which is made of at least the second calibrator and the reagent, or controlling the second photometric component to perform optical measurement on the reaction liquid in the third reaction container, which is independent of the second reaction container, which is made of at least the reagent and the second calibrator transferred from the second reaction container to the third reaction container, to obtain the third initial photometric value; Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once; The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once; The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter includes: performing the following process at least once: controlling the second photometric component to perform optical measurement on the reaction liquid in the fourth reaction vessel made of at least the third calibrator and reagents to obtain the fourth initial photometric value; The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once; Among them, one of the first optical measurement component and the second optical measurement component is a transmission light detector, and the other is a scattering light detector; Alternatively, when the different detection parameters include different components and / or different concentrations of reagents and different photometric components, the sample measurement assembly includes a first photometric component and a second photometric component; The control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter includes: performing the following process at least once: controlling the reagent dispensing component to add the first reagent into the first reaction container; controlling the sample dispensing component to add the first calibrator into the first reaction container; controlling the first photometric component to perform optical measurement on the first reaction liquid in the first reaction container, which is at least made of the first calibrator and the first reagent, to obtain the first initial photometric value; The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once; The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the reagent dispensing component to add the first reagent into the second reaction container; controlling the sample dispensing component to add the second calibrator into the second reaction container; controlling the first photometric component to perform optical measurement on the second reaction liquid in the second reaction container, which is at least composed of the second calibrator and the first reagent, to obtain the second initial photometric value; controlling the reagent dispensing component to add the second reagent into the second reaction container or controlling the reagent dispensing component to add the second reagent into a third reaction container independent of the second reaction container; controlling the second photometric component to perform optical measurement on the third reaction liquid in the second reaction container, which is at least composed of the second reagent and the second reaction liquid, or controlling the second photometric component to perform optical measurement on the third reaction liquid in the third reaction container, which is at least composed of the second reagent and the second reaction liquid transferred from the second reaction container to the third reaction container, to obtain the third initial photometric value; Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once; The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once; The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator using the second detection parameter includes: performing the following process at least once: controlling the reagent dispensing component to add the first reagent into the fourth reaction container; controlling the sample dispensing component to add the third calibrator into the fourth reaction container; controlling the reagent dispensing component to add the second reagent into the fourth reaction container; controlling the second photometric component to perform optical measurement on the fourth reaction solution in the fourth reaction container, which is at least made of the third calibrator, the first reagent, and the second reagent, to obtain the fourth initial photometric value; The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once; The first reagent and the second reagent differ in at least one of the following aspects: composition and concentration; One of the first optical measurement component and the second optical measurement component is a transmission light detector, and the other is a scattering light detector; Alternatively, when the different detection parameters include light of different wavelengths, the control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters includes: performing the following process at least once: controlling the photometric component to perform optical measurement of light of the first wavelength on the reaction liquid in the first reaction vessel made of at least the first calibrator and reagents to obtain the first initial photometric value; The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once; The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least one of the following processes: controlling the photometric component to perform optical measurement of light of the first wavelength on the reaction liquid made of at least the second calibrator and reagent in the second reaction container to obtain the second initial photometric value; controlling the photometric component to perform optical measurement of light of the second wavelength on the reaction liquid made of at least the second calibrator and reagent in the second reaction container or controlling the photometric component to perform optical measurement of light of the second wavelength on the reaction liquid made of at least the reagent and the second calibrator transferred from the second reaction container to the third reaction container in a third reaction container independent of the second reaction container to obtain the third initial photometric value; Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once; The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once; The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter includes: performing the following process at least once: controlling the photometric component to perform optical measurement of the second wavelength of light on the reaction liquid made of at least the third calibrator and reagent in the fourth reaction vessel to obtain the fourth initial photometric value; The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once; Wherein, the second wavelength is greater than or less than the first wavelength; Alternatively, when the different detection parameters include different reaction times, the control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters includes: performing the following process at least once: controlling the photometric component to perform optical measurement on the reaction liquid in the first reaction container prepared by at least the first calibrator and reagent under the first reaction time to obtain the first initial photometric value; The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once; The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the photometric component to perform optical measurement on the reaction solution prepared in the second reaction container by at least the second calibrator and reagent under the first reaction time to obtain the second initial photometric value; controlling the photometric component to perform optical measurement on the reaction solution prepared in the second reaction container by at least the second calibrator and reagent under the second reaction time to obtain the third initial photometric value; Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once; The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once; The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter includes: performing the following process at least once: controlling the photometric component to perform optical measurement on the reaction liquid prepared in the fourth reaction vessel by at least the third calibrator and reagent under the second reaction time to obtain the fourth initial photometric value; The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once; Wherein, the second reaction time is greater than or less than the first reaction time; Alternatively, when the different detection parameters include different blank durations, the control of the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameters includes: performing the following process at least once: controlling the photometric component to perform optical measurement on the reaction solution in the first reaction vessel prepared by at least the first calibrator and reagent under the first blank duration to obtain the first initial photometric value; The process of obtaining the first optical measurement result includes: obtaining the first optical measurement result based on the first initial optical measurement value obtained in the first sub-calibration process of the first project at least once; The control of the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter includes: performing at least once the following process: controlling the photometric component to perform optical measurement on the reaction solution prepared in the second reaction container by at least the second calibrator and reagent under the first blank time to obtain the second initial photometric value; controlling the photometric component to perform optical measurement on the reaction solution prepared in the second reaction container by at least the second calibrator and reagent under the second blank time to obtain the third initial photometric value; Obtaining the second optical measurement result includes: obtaining the second optical measurement result based on the second initial optical measurement value obtained in the second sub-calibration process of the first project at least once; The process of obtaining the third optical measurement result includes: obtaining the third optical measurement result based on the third initial optical measurement value obtained in the second sub-calibration process of the first item at least once; The control of the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter includes: performing the following process at least once: controlling the photometric component to perform optical measurement on the reaction solution prepared in the fourth reaction vessel by at least the third calibrator and reagent under the second blank time to obtain the fourth initial photometric value; The process of obtaining the fourth optical measurement result includes: obtaining the fourth optical measurement result based on the fourth initial optical measurement value obtained in the third sub-calibration process of the first item at least once; Wherein, the second blank duration is greater than or less than the first blank duration.

9. The sample analyzer as described in any one of claims 1 to 4 or 6, characterized in that: The sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component includes a sample needle for adding the calibrator into the reaction container. The reagent dispensing component is used to add reagents into the reaction container. The optical measurement component is used to perform optical measurements on the reaction solution in the reaction container, which is made of at least the calibrator and the reagent. The method of controlling the sample measurement component to perform the first sub-calibration process of the first item at least once on the first calibrator through the first detection parameter to obtain the first photometric result includes: controlling the sample needle to distribute the first calibrator of the same concentration into a first number of reaction containers, controlling the photometric component to perform optical measurement on the reaction solution made of at least the first calibrator and the reagent in the first number of reaction containers to obtain the first number of first initial photometric values, and obtaining the first photometric result based on the first number of first initial photometric values; The method of controlling the sample measurement component to perform a second sub-calibration process of the first item on the second calibrator at least once using the first detection parameter and the second detection parameter to obtain a second photometric result and a third photometric result includes: controlling the sample needle to distribute the second calibrator of the same concentration into a second number of reaction containers; controlling the photometric component to perform optical measurements on the reaction solution made of at least the second calibrator and the reagent in the second number of reaction containers to obtain a second number of second initial photometric values ​​and a third number of third initial photometric values; obtaining a second photometric result based on the second number of second initial photometric values; obtaining a third photometric result based on the second number of third initial photometric values; and obtaining a second initial photometric value and a third initial photometric value by performing optical measurements on the reaction solution made of at least the second calibrator and the reagent in each of the second number of reaction containers. The method of controlling the sample measurement component to perform the third sub-calibration process of the first item at least once on the third calibrator through the second detection parameter to obtain the fourth photometric result includes: controlling the sample needle to distribute the third calibrator of the same concentration into the third number of reaction containers respectively; controlling the photometric component to perform optical measurement on the reaction solution made of at least the third calibrator and the reagent in the third number of reaction containers respectively to obtain the third number of fourth initial photometric values; and obtaining the fourth photometric result based on the third number of fourth initial photometric values. Wherein, the second quantity is greater than or equal to the first quantity, and greater than or equal to the third quantity, and less than the sum of the first quantity and the third quantity.

10. The sample analyzer as described in claim 1, characterized in that: The sample analyzer also includes a display, which is at least used to display the calibration results interface of the first item; After obtaining the first calibration data, the controller is further configured to control the display to display the first calibration data in the calibration result interface of its first item.

11. The sample analyzer as described in claim 10, characterized in that: The first calibration data is a continuous first calibration curve, and controlling the display to display the first calibration data in the calibration result interface of its first item includes: controlling the display to display the continuous first calibration curve in the calibration result interface of its first item; Alternatively, the first calibration data includes a second calibration curve and a third calibration curve, which are spaced apart from each other. Obtaining the first calibration data for the first item based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result includes: obtaining the second calibration curve based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result. The third calibration curve is obtained based on the concentration of the target analyte in the second calibrator and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result; Controlling the display to display the first calibration data in the calibration result interface of its first item includes: controlling the display to display the second calibration curve and the third calibration curve in the calibration result interface of its first item.

12. The sample analyzer as described in any one of claims 1 to 4, or 6, 10, or 11, characterized in that: The sample analyzer also includes a display, which is at least used to display the calibration result details interface for each of the calibrators used in the first project. The calibration result details interface for each of the calibrators displays the number of times the sub-calibration process is repeated for that calibrator and the photometric results. The controller is also configured to: In response to a first trigger command, the display is controlled to show the calibration result details interface of the first calibrator. The calibration result details interface of the first calibrator shows the number of times the first sub-calibration process is repeated and the first photometric result. In response to the second trigger command, the display is controlled to show the calibration result details interface of the second calibrator. The calibration result details interface of the second calibrator shows the number of times the second calibrator repeats the second sub-calibration process, the second photometric result, and the third photometric result. In response to a third trigger command, the display is controlled to show the calibration result details interface of the third calibrator. The calibration result details interface of the third calibrator shows the number of times the third calibrator repeats the third sub-calibration process and the fourth photometric result.

13. The sample analyzer as described in claim 12, characterized in that: The display is also used to display the calibration result interface of the first item, which at least displays the first calibration data and information for each of the calibrators used in the sub-calibration process of the first item. The first triggering instruction includes: an instruction formed by an operator viewing the first calibrator in the calibration result interface of the first item through at least one of screen touch, mouse operation, keyboard operation, and voice input; The second triggering instruction includes: an instruction formed by the operator viewing the second calibrator in the calibration result interface of the first item through at least one of screen touch, mouse operation, keyboard operation, and voice input; The third trigger command includes: a command generated by an operator viewing the third calibrator in the calibration result interface of the first item through at least one of screen touch, mouse control, keyboard control, and voice input.

14. The sample analyzer as described in any one of claims 1 to 4, or 6, 10, or 11, characterized in that: The control of the sample measurement component to perform the first item sample measurement procedure on the same sample used to detect the target analyte using the first detection parameter and the second detection parameter, to obtain sample photometric results, and to obtain the detection result of the concentration of the target analyte in the sample based on the sample photometric results and the first calibration data, including: The sample measurement component is controlled to perform the first item sample measurement process on the same sample used to detect the target object through the first detection parameter and the second detection parameter, so as to obtain the fifth optical measurement result corresponding to the first detection parameter and the sixth optical measurement result corresponding to the second detection parameter; Based on the fifth photometric result and the first calibration data, the first measurement data is obtained; Based on the sixth photometric result and the first calibration data, the second measurement data is obtained; Based on the first measurement data and the second measurement data, the detection results of the concentration of the target analyte in the sample are obtained.

15. The sample analyzer as described in any one of claims 1 to 4, or 6, 10, or 11, characterized in that: The first calibration data includes a second calibration curve, a third calibration curve, and a fourth calibration curve; The controller is also configured to execute the following calibration procedure for the first item: control the sample measurement component to perform the fourth sub-calibration procedure of the first item for the fourth time on the fourth calibrator to obtain the seventh and eighth photometric results; control the sample measurement component to perform the fifth sub-calibration procedure of the first item for the fifth time on the fifth calibrator to obtain the ninth photometric result; The first calibration data for the first item is obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result, including: The second calibration curve is obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result. The third calibration curve is obtained based on the concentration of the target analyte in the second calibrator and the third photometric result, the concentration of the target analyte in the third calibrator and the fourth photometric result, and the concentration of the target analyte in the fourth calibrator and the seventh photometric result; The fourth calibration curve is obtained based on the concentration of the target analyte in the fourth calibrator and the eighth photometric result, the concentration of the target analyte in the fifth calibrator and the ninth photometric result; Wherein, the concentration of the target analyte in the fourth calibrator is greater than the concentration of the target analyte in the third calibrator; The second calibration curve, the third calibration curve, and the fourth calibration curve are connected to form a continuous calibration curve, or at least two of the second calibration curve, the third calibration curve, and the fourth calibration curve are spaced apart from each other.

16. A sample analyzer, characterized in that: include: A sample measurement assembly for performing a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte is known. And a sample measurement procedure for performing the first item on a sample used to detect the target analyte; The display is at least used to display the calibration result details interface for each of the calibrators used in the first project, wherein the calibration result details interface for each of the calibrators displays the number of times the sub-calibration process is repeated for that calibrator and the photometric results; The controller is configured to: In response to a first trigger command, the display is controlled to show the calibration result details interface of the first calibrator used in the first item. The calibration result details interface of the first calibrator shows the first number of times the sample measurement component repeatedly performs the sub-calibration process of the first item on the first calibrator using the first detection parameter and the first photometric result obtained by the sample measurement component performing the sub-calibration process of the first item on the first calibrator using the first detection parameter the first number of times. In response to the second trigger command, the display is controlled to show the calibration result details interface of the second calibrator. The calibration result details interface of the second calibrator shows the second number of times the sample measurement component repeatedly performs the sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter, as well as the second and third photometric results obtained by the sample measurement component performing the sub-calibration process of the first item on the second calibrator using the first detection parameter and the second detection parameter for the second number of times. In response to a third trigger command, the display is controlled to show the calibration result details interface of the third calibrator. The calibration result details interface of the third calibrator shows the third number of times the sample measurement component repeatedly performs the sub-calibration process of the first item on the third calibrator using the second detection parameter, and the fourth photometric result obtained by the sample measurement component performing the sub-calibration process of the first item on the third calibrator using the second detection parameter. Wherein, the concentration of the target analyte in the second calibrator is greater than the concentration of the target analyte in the first calibrator, but less than the concentration of the target analyte in the third calibrator; The first detection parameter and the second detection parameter are different detection parameters.

17. The sample analyzer as described in claim 16, characterized in that: The second number is greater than or equal to the first number, and greater than or equal to the third number, and less than the sum of the first number and the third number.

18. The sample analyzer as described in claim 17, characterized in that: The first number, the second number, and the third number are all greater than or equal to two; And / or, the first number is equal to the third number.

19. The sample analyzer according to any one of claims 16 to 18, characterized in that: The sample measurement assembly includes a sample dispensing component, a reagent dispensing component, and an optical measurement component. The sample dispensing component is used to add the calibrator into the reaction container, the reagent dispensing component is used to add the reagent into the reaction container, and the optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least the calibrator and the reagent. The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

20. The sample analyzer according to any one of claims 16 to 18, characterized in that: The controller is also configured to: Based on the concentration of the target analyte in the first calibrator and the first photometric result, and the concentration of the target analyte in the second calibrator and the second photometric result, a second calibration curve for the first item is obtained; Based on the concentration of the target analyte in the second calibrator and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result, a third calibration curve for the first item is obtained; The second calibration curve and the third calibration curve are connected to form a continuous first calibration curve; or the second calibration curve and the third calibration curve are set at intervals.

21. A sample analyzer, characterized in that: include: A sample measurement assembly for performing a calibration procedure for a first item on a calibrator containing a target analyte and the concentration of the target analyte is known. And a sample measurement procedure for performing the first item on a sample used to detect the target analyte; A controller, configured to control the operation of the sample measurement component; The sample measurement component includes a sample dispensing component and an optical measurement component. The sample dispensing component includes a sample needle for adding the calibrator into the reaction container. The optical measurement component is used to perform optical measurement on the reaction solution in the reaction container, which is made of at least the calibrator and the reagent. The controller is configured to perform the following calibration procedure for the first item: The sample needle is controlled to dispense the first calibrator of the same concentration into a first number of reaction containers, and the photometric component is controlled to perform optical measurements on the reaction solution made of at least the first calibrator and the reagent in the first number of reaction containers to obtain a first photometric result; The sample needle is controlled to dispense the second calibrator of the same concentration into the second number of reaction containers, and the photometric component is controlled to perform optical measurements on the reaction solution in the second number of reaction containers, which is made of at least the second calibrator and the reagent, to obtain a second photometric result and a third photometric result. The sample needle is controlled to dispense the same concentration of the third calibrator into the third number of reaction containers, and the photometric component is controlled to perform optical measurements on the reaction solution in the third number of reaction containers, which is made of at least the third calibrator and the reagent, to obtain a fourth photometric result. First calibration data is obtained based on the concentration of the target analyte in the first calibrator and the first photometric result, the concentration of the target analyte in the second calibrator and the second photometric result and the third photometric result, and the concentration of the target analyte in the third calibrator and the fourth photometric result; The controller is further configured to: control the sample measurement component to perform the sample measurement procedure of the first item on the same sample used to detect the target analyte, obtain sample photometric results, and obtain the detection result of the concentration of the target analyte in the sample based on the sample photometric results and the first calibration data; Wherein, the concentration of the target analyte in the second calibrator is greater than the concentration of the target analyte in the first calibrator, but less than the concentration of the target analyte in the third calibrator; The second quantity is greater than or equal to the first quantity, and greater than or equal to the third quantity, and less than the sum of the first quantity and the third quantity.

22. The sample analyzer as described in claim 21, characterized in that: The first quantity, the second quantity, and the third quantity are all greater than or equal to two; And / or, the first quantity is equal to the third quantity.

23. The sample analyzer as described in claim 21 or 22, characterized in that: The first photometric result is obtained by the sample measurement component measuring the first calibrator using the first detection parameters; The second and third optical measurement results are obtained by the sample measurement component measuring the second calibrator using the first and second detection parameters, respectively. The fourth photometric result is obtained by the sample measurement component measuring the third calibrator using the second detection parameters; Wherein, the first detection parameter and the second detection parameter are different detection parameters; The different detection parameters include any of the following: different components and / or different concentrations of reagents, different photometric components, different wavelengths of light, different reaction times, and different blank times.

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