A self-monitoring sterilization laminar flow transfer window

Abstract

This invention relates to a self-monitoring sterilization laminar flow transfer window, belonging to the technical field of laminar flow transfer windows. By introducing a particle size monitoring component, a dynamic sterilization component, a feedback prompting module, and an embedded control system, and establishing an electrical connection and control link between a data acquisition interface, a threshold storage unit, and a threshold comparison unit within the transfer window itself, the particle size monitoring component can collect airborne particulate matter in the transfer cavity online and compare it with a preset threshold in real time. The comparison result is directly used to drive the dynamic sterilization component to perform linked sterilization, control the displacement drive motor and push rod motor to adjust the airflow organization, and automatically trigger the feedback prompting module to issue a prompt when the particle size exceeds the limit. This effectively solves the problem of lacking a long-term stable online particle size monitoring system in the cavity and its linked closed-loop structure with sterilization and prompting.

Description

Technical Field

[0001] This invention belongs to the field of laminar flow transfer window technology, specifically relating to a self-monitoring sterilization laminar flow transfer window. Background Technology

[0002] A laminar flow pass-through window is a device used for transferring materials between areas of different cleanliness levels. It is commonly found in pharmaceutical, hospital, biological laboratory, and microelectronics settings. Existing laminar flow pass-through windows typically include a pass-through window body and an internal pass-through chamber. The pass-through chamber has openable doors on opposite sides for inserting and removing materials. The body contains an air supply and purification structure to provide unidirectional laminar airflow, allowing purified air to enter the pass-through chamber and replace the air, thus reducing the risk of cross-contamination caused by the introduction of particulate matter and microorganisms during the transfer process. Some products are also equipped with sterilization components such as ultraviolet lamps to disinfect the air or surfaces of items within the pass-through chamber.

[0003] In practical applications, whether a pass-through window truly meets cleanliness requirements hinges on whether the air cleanliness within the pass-through chamber remains under control during disturbances such as door opening and closing, item placement, and personnel operation. To achieve "control," the most direct basis is obtaining continuous data on cleanliness parameters such as particulate matter concentration within the pass-through chamber. However, existing equipment often struggles to generate continuous, online particulate matter detection data within the chamber, typically due to engineering limitations: First, online particulate matter detection generally requires stable and repeatable sampling conditions, such as sampling flow rate, representativeness of sampling locations, and sealing of sampling channels. The pass-through chamber has relatively limited space and contains unidirectional laminar airflow. Directly placing detection components or sampling structures within the chamber can easily alter the local flow field, creating obstructions or dead zones, leading to inconsistencies between the detection point data and the actual cleanliness distribution within the chamber. Furthermore, door opening and closing cause short-term turbulence and external air intrusion, resulting in transient changes in cleanliness. Without a continuous sampling and data processing mechanism linked to the equipment, intermittent measurements alone are insufficient to promptly capture risks. Second, pass-through chambers typically require… Frequent wiping and disinfection or exposure to ultraviolet light are necessary. If the detection components are exposed to radiation, disinfectants, condensation, moisture, and high-speed airflow for extended periods, they are prone to drift, aging, or increased maintenance requirements. Coupled with calibration and cost factors, many products tend to rely on external environmental monitoring or handheld particle counters for periodic spot checks, making it objectively difficult to obtain "continuous online data within the cavity." Furthermore, the reason why existing sterilization components often exhibit fixed intensity combined with timed or manual start-stop is also due to the lack of a closed-loop condition at the system level: without real-time contamination level data, the sterilization intensity cannot be dynamically adjusted based on the contamination level, and the operating time can only be set based on experience. When the sterilization action and particle size data lack linkage control logic, the equipment is also unlikely to automatically trigger alarms or interface prompts when particulate matter exceeds the standard. Users can only rely on manual inspection, recording, or external spot checks to determine whether the standard is exceeded and whether more disinfection is needed. Therefore, it is difficult to achieve unmanned real-time monitoring and process control, which in turn affects the reliability and compliance of use in sterile environments. Summary of the Invention

[0004] To address the aforementioned problems in the existing technology, this invention provides a self-monitoring sterilization laminar flow transfer window. This solves the problem that existing laminar flow transfer windows lack long-term stable online particle size monitoring within the cavity and a closed-loop structure linking sterilization and alerts, making it difficult to identify and automatically handle cleanliness risks in a timely manner. Consequently, they rely excessively on manual inspections and external sampling, making it difficult to achieve unmanned real-time monitoring and process control.

[0005] The objective of this invention can be achieved through the following technical solutions: A self-monitoring sterilization laminar flow transfer window includes a transfer window body, a transfer cavity formed within the transfer window body, a first opening and closing door and a second opening and closing door respectively on opposite sides of the transfer cavity, a laminar flow air supply assembly within the transfer window body, the laminar flow air supply assembly having an air supply outlet communicating with the transfer cavity and the air supply outlet being arranged towards the transfer cavity, and a variable guide vane mechanism being provided at the air supply outlet of the laminar flow air supply assembly, the variable guide vane mechanism including guide vanes driven by a push rod motor, the push rod motor driving the guide vanes to change the angle through a linkage mechanism to change the airflow organization within the transfer cavity; A particle size monitoring component is provided on the sampling channel connected to the transfer cavity. The particle size monitoring component includes: a multi-station switching turntable, which includes a detection station connected to the transfer cavity and a maintenance station connected to the calibration gas path; and a displacement drive motor for driving the turntable to switch between the detection station and the maintenance station, so that the particulate sensor is connected to the sampling channel when in the detection station and connected to the calibration gas path when in the maintenance station, thereby physically disconnecting from the transfer cavity. A dynamic sterilization component is provided in the airflow channel of the laminar flow air supply component. A feedback prompting module is provided on the outside of the transfer window body. An embedded control system is provided in the transfer window body. The embedded control system is electrically connected to the particle size monitoring component, the dynamic sterilization component, the feedback prompting module, and the displacement drive motor and the push rod motor, respectively. The embedded control system includes a data acquisition interface, a threshold storage unit, and a threshold comparison unit. The data acquisition interface is connected to the particle size monitoring component, and the input terminal of the threshold comparison unit is connected to the data acquisition interface and the threshold storage unit. The embedded control system outputs control signals based on particle size data to drive the displacement drive motor and the push rod motor to achieve linkage control between particle size monitoring and airflow organization adjustment. When the particle size exceeds the limit, the system drives the feedback prompt module to issue a prompt.

[0006] As a further embodiment of the present invention, the particle size monitoring component includes at least one particulate matter sensor and a sampling channel connected to the particulate matter sensor. The air inlet of the sampling channel opens into the transmission cavity and is arranged along the main airflow direction pointed to by the air outlet. A flow stabilizing cavity, a flow limiting device and a micro sampling pump are provided on the sampling channel.

[0007] As a further embodiment of the present invention, the first opening and closing door and the second opening and closing door are respectively provided with door status detection components, the door status detection components are electrically connected to the embedded control system, and the output terminal of the door status detection components is connected to the threshold comparison unit.

[0008] As a further embodiment of the present invention, the transmission window body is provided with an air volume monitoring component, which is located upstream and downstream of the airflow channel of the laminar flow air supply component. The air volume monitoring component is electrically connected to the embedded control system, and the output end of the air volume monitoring component is connected to the threshold comparison unit.

[0009] As a further embodiment of the present invention, the feedback prompting module includes an audible and visual alarm and a digital display interface, and the audible and visual alarm and the digital display interface are electrically connected to the feedback control interface.

[0010] As a further embodiment of the present invention, the embedded control system includes a trend analysis unit, the input end of which is connected to a data acquisition interface, the output end of which is connected to a threshold comparison unit, and the parameters output by the trend analysis unit include particulate matter concentration change rate parameters, concentration fluctuation parameters, and particle size distribution parameters.

[0011] As a further embodiment of the present invention, the threshold storage unit stores multiple sets of threshold parameters and associates them with influencing factor identifiers. The influencing factor identifiers include door status identifiers and airflow status identifiers. The threshold comparison unit includes a multi-parameter evaluation subunit. The input terminal of the multi-parameter evaluation subunit is connected to at least the detection data of the particle size monitoring component, the parameters output by the trend analysis unit, the door status signal of the door status detection component, and the airflow signal of the airflow monitoring component. The multi-parameter evaluation subunit outputs multi-level cleanliness risk level signals, and the sterilization control interface and the feedback control interface are respectively connected to the cleanliness risk level signals.

[0012] As a further embodiment of the present invention, the multi-parameter evaluation subunit includes a hysteresis comparator and a continuous over-limit determination timer. The hysteresis comparator stores an upper threshold and a lower threshold, and the continuous over-limit determination timer stores an over-limit duration parameter and a recovery stabilization time parameter.

[0013] As a further embodiment of the present invention, the dynamic sterilization component includes a sterilization execution unit, an adjustable drive module, and a sterilization output monitoring component. The input end of the adjustable drive module is connected to the sterilization control interface, and its output end is connected to the sterilization execution unit. The sterilization output monitoring component is located at a position corresponding to the sterilization execution unit and is electrically connected to the embedded control system. The output end of the sterilization output monitoring component is connected to the threshold comparison unit and the sterilization control interface. The embedded control system further includes a dose accumulation unit, which is connected to the sterilization output monitoring component and the feedback control interface.

[0014] As a further embodiment of the present invention, the particulate sensor is disposed in a monitoring cavity isolated from the transfer cavity. The monitoring cavity and the transfer cavity are connected through the sampling channel. The monitoring cavity is provided with a shield against ultraviolet radiation and a replaceable breathable and dustproof isolation component. The transfer window also includes a reference sampling assembly, which includes a reference filter cavity connected to the sampling channel and a sampling switching valve disposed on the sampling channel. A zero-particle filter is disposed in the reference filter cavity. The sampling switching valve is electrically connected to the embedded control system. The embedded control system includes a sensor health monitoring unit, which is connected to the data acquisition interface, the sampling switching valve, and the feedback control interface, respectively.

[0015] The beneficial effects of this invention are as follows: This invention introduces a particle size monitoring component, a dynamic sterilization component, a feedback prompting module, and an embedded control system. It establishes an electrical connection and control link between a data acquisition interface, a threshold storage unit, and a threshold comparison unit within the transfer window itself. This enables the particle size monitoring component to collect airborne particulate matter within the transfer cavity online and compare it in real-time with preset thresholds. The comparison results are directly used to drive the dynamic sterilization component to perform linked sterilization, control the displacement drive motor and push rod motor to adjust airflow organization, and automatically trigger the feedback prompting module to issue a warning when particle size exceeds the limit. Structurally, this forms an integrated closed-loop control system of "monitoring-sterilization-feedback," transforming the passive management mode that previously relied on manual inspections and external sampling into a system where real-time data acquisition, threshold judgment, linked handling, and status prompts are automatically completed by the equipment. This effectively solves the problems in existing technologies where the lack of a long-term stable online particle size monitoring system within the cavity and its linked closed-loop structure with sterilization and prompts leads to difficulties in timely identification and automatic handling of cleanliness risks, and in achieving unmanned real-time monitoring and process control. Attached Figure Description

[0016] To facilitate understanding by those skilled in the art, the present invention will be further described below with reference to the accompanying drawings.

[0017] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 The flowchart is of the integrated closed-loop control system for monitoring, sterilization, and feedback of this invention. Figure 3 This is a schematic diagram of the variable guide vane mechanism of the present invention.

[0018] Explanation of key component symbols: In the figure: 1. Transfer window body; 2. Transfer chamber; 3. First opening and closing door; 4. Second opening and closing door; 5. Laminar flow air supply assembly; 6. Variable guide vane mechanism. Detailed Implementation

[0019] To further illustrate the technical means and effects of the present invention in achieving its intended purpose, the following detailed description of the specific implementation methods, structures, features, and effects of the present invention, in conjunction with the accompanying drawings and preferred embodiments, is provided.

[0020] Please see Figure 1 - Figure 3 As shown, this embodiment provides a self-monitoring sterilization laminar flow transfer window. A self-monitoring sterilization laminar flow transfer window, The system includes a transfer window body 1, a transfer cavity 2 is formed inside the transfer window body 1, a first opening and closing door 3 and a second opening and closing door 4 are respectively provided on opposite sides of the transfer cavity 2, a laminar flow air supply assembly 5 is provided inside the transfer window body 1, the laminar flow air supply assembly 5 has an air supply outlet communicating with the transfer cavity 2 and the air supply outlet is arranged facing the transfer cavity 2, and a variable guide vane mechanism 6 is provided at the air supply outlet of the laminar flow air supply assembly 5. The variable guide vane mechanism 6 includes guide vanes driven by a push rod motor. The push rod motor drives the guide vanes to change the angle through a linkage mechanism to change the airflow organization in the transfer cavity 2. A particle size monitoring component is provided on the sampling channel connected to the transfer chamber 2. The particle size monitoring component includes: a multi-station switching turntable, which includes a detection station connected to the transfer chamber 2 and a maintenance station connected to the calibration gas path; and a displacement drive motor, which drives the turntable to switch between the detection station and the maintenance station, so that the particulate sensor is connected to the sampling channel when it is in the detection station and connected to the calibration gas path when it is in the maintenance station, thereby physically disconnecting it from the transfer chamber 2. A dynamic sterilization component is provided in the airflow channel of the laminar flow air supply component 5. A feedback prompting module is provided on the outside of the transfer window body 1. An embedded control system is provided inside the transfer window body 1. The embedded control system is electrically connected to the particle size monitoring component, the dynamic sterilization component, the feedback prompting module, and the displacement drive motor and the push rod motor, respectively. The embedded control system includes a data acquisition interface, a threshold storage unit, and a threshold comparison unit. The data acquisition interface is connected to the particle size monitoring component, and the input of the threshold comparison unit is connected to the data acquisition interface and the threshold storage unit. The embedded control system outputs control signals based on particle size data to drive the displacement drive motor and the push rod motor to achieve linkage control between particle size monitoring and airflow organization adjustment. When the particle size exceeds the limit, the system drives the feedback prompt module to issue a prompt.

[0021] It is necessary to further explain that the above-described structure, divided into transfer chamber 2 and double doors, laminar flow air supply component 5, particle size monitoring component on sampling channel, dynamic sterilization component in airflow channel, external feedback and prompting module, embedded control system and its internal interfaces and unit connections, is to decompose cleanroom risk control into implementable hardware links. Transfer chamber 2 and double doors define the location and boundary of contamination disturbances. The air outlet of laminar flow air supply component 5 faces transfer chamber 2 to ensure the formation of the dominant airflow direction within transfer chamber 2, thus providing a physical basis for stable sampling and contamination dilution. The particle size monitoring component is located in the sampling channel connected to transfer chamber 2, making it easier to obtain repeatable flow rates or paths during sampling. The system optimizes the flow path and reduces direct interference with the flow field within the cavity. The dynamic sterilization component is located within the airflow channel, allowing the sterilization effect to be naturally coupled with the airflow organization. This ensures sterilization of the clean or circulating airflow entering the transfer cavity 2. The feedback and prompt module is located on the outside of the main body, allowing the operator to obtain the status without opening the door or damaging the clean boundary. The embedded control system uses a modular connection of "acquisition-storage-comparison-two-way output interface", which can solidify the "objective comparison between the monitored value and the threshold" into the internal logic of the equipment. This transforms the triggering basis for sterilization and prompts from experience or manual intervention to data or thresholds, fundamentally improving unmanned monitoring capabilities, consistency of risk response, and compliance traceability. Furthermore, to address the problem in existing laminar flow transfer windows that lack a stable, long-term online particle size monitoring system and a closed-loop linkage structure with sterilization and alerts, leading to difficulties in timely identification and automatic handling of cleanliness risks and excessive reliance on manual inspections and external sampling, thus hindering unmanned real-time monitoring and process control, this embodiment introduces a particle size monitoring component, a dynamic sterilization component, a feedback alert module, and an embedded control system. An electrical connection and control link are established within the transfer window body 1 for a data acquisition interface, a threshold storage unit, and a threshold comparison unit. This enables the particle size monitoring component to collect airborne particulate matter within the transfer cavity online and compare it with a preset threshold in real time. The results are directly used to drive the dynamic sterilization component to perform linked sterilization, control the displacement drive motor and push rod motor to adjust the airflow organization, and automatically trigger the feedback prompt module to issue a prompt when the particle size exceeds the limit. Thus, in terms of structure, an integrated closed-loop control system of "monitoring-sterilization-feedback" is formed. The original passive management mode that relied on manual inspection and external sampling is transformed into a real-time data acquisition, threshold judgment, linked handling and status prompt that is automatically completed by the equipment. This effectively solves the problem in the existing technology that the lack of long-term stable online particle size monitoring in the cavity and its linkage closed-loop structure with sterilization and prompting makes it difficult to identify and automatically handle cleanliness risks in a timely manner, and difficult to achieve unmanned real-time monitoring and process control.

[0022] In pharmaceutical cleanrooms, cell and microbiology laboratories, and other similar settings, the transfer chamber 2 of a transfer window is typically compact and contains unidirectional laminar flow. The opening and closing of the door and the placement of items cause instantaneous changes in the local flow field. If the particulate sensor is directly exposed within the chamber or the sampling conditions are unstable, phenomena such as unrepresentative sampling points, inconsistent sampling flow rates, and reading fluctuations caused by turbulent transients can easily occur. Once the sampling is unstable or lacks representativeness, it directly affects the reliability of the monitoring-sterilization-feedback closed loop, manifesting as false alarms, missed alarms, or delayed linkage. To address this, in one embodiment, the particle size monitoring component includes at least one particulate sensor and a sampling channel connected to the particulate sensor. The air inlet of the sampling channel opens into the transfer chamber 2 and extends along the air outlet. The sampling channel is arranged in the direction of the main airflow, and a flow stabilizing cavity, a flow restrictor, and a micro sampling pump are set on the sampling channel. The particle size monitoring component includes a particulate sensor and a sampling channel connected to it. The air inlet of the sampling channel is opened in the transfer cavity 2 and arranged in the direction of the main airflow pointing from the air outlet. At the same time, the flow stabilizing cavity, the flow restrictor, and the micro sampling pump are set on the sampling channel to provide more controllable sampling conditions from a structural point of view. The flow stabilizing cavity and the flow restrictor are used to suppress airflow pulsation and improve the repeatability of sampling flow rate. The micro sampling pump is used to maintain stable sampling capability when the door is opened and closed or the pressure difference in the cavity changes. Sampling along the main airflow direction helps to improve the representativeness of the sampling and reduce the randomness caused by backflow and recirculation areas, thereby improving the stability and reliability of the monitoring data. Following the above embodiments, the sampling port of the sampling channel is prone to blockage in high dust environments (such as pharmaceutical weighing). To better avoid this problem, a self-cleaning mechanism is set at the air inlet of the sampling channel. The self-cleaning mechanism includes a scraper or an openable and closable baffle and a back-blowing air path. When the embedded control system detects a decrease in sampling flow or an abnormal pressure difference, it drives the self-cleaning mechanism to perform scraping or back-blowing actions to remove accumulated dust. This design can also solve the problem of hardware physical performance degradation under long-term unattended operation.

[0023] In high-frequency transfer operations, such as frequent material turnover between aseptic filling auxiliary areas, clean corridors, and sterile rooms, the door status (e.g., open, closed, interlock switching) significantly alters the boundary conditions of transfer chamber 2: when the door is open, outside air intrudes, and turbulence intensifies; after the door closes, laminar flow gradually recovers. If the closed-loop logic relies solely on granular instantaneous data without recognizing the door status, two types of objective problems can easily arise: first, transient disturbances during the door opening phase may cause a short-term increase in particle size, triggering unnecessary alarms and sterilization linkages; second, after the door closes, stricter cleanliness judgment and recovery confirmation are required, but the lack of a door status signal will prevent the threshold judgment from matching the operating conditions, thus affecting the adaptability of the closed-loop control. In one embodiment, the first opening and closing... Door 3 and the second opening / closing door 4 are each equipped with a door status detection component. The door status detection component is electrically connected to the embedded control system, and the output terminal of the door status detection component is connected to the threshold comparison unit. Here, by setting door status detection components on the first opening / closing door 3 and the second opening / closing door 4 respectively and connecting their output terminals to the threshold comparison unit, the door status becomes one of the input quantities involved in the judgment. The direct benefit of doing so is that the closed-loop system not only knows the granularity but also knows under what door operating conditions the granularity occurs. Structurally, this provides a foundation for subsequent multi-threshold and multi-parameter evaluation, reduces the risk of false triggering caused by door opening transients, and improves the reliability of cleanliness status confirmation after door closure. This makes the overall closed loop more stable and more in line with the cleanroom operation logic under actual operating conditions.

[0024] In applications involving continuous operation or long-term use, such as 24-hour operation in pharmaceutical cleanrooms, the airflow or resistance of the laminar flow air supply system can change due to factors such as increased HEPA filter load, decreased fan performance, and duct blockage. These airflow changes have two main impacts: firstly, reduced ventilation capacity of the transfer chamber 2 makes it more difficult for particulate matter to be quickly carried away, leading to increased cleanliness risks; secondly, sampling and particle distribution also change with the flow field, causing the same particle size value to have different risk implications under different airflow conditions. If the closed-loop system does not possess key operating parameters such as airflow or pressure difference, it is difficult to make a more accurate assessment of cleanliness risks. To avoid these problems, in one embodiment, an airflow monitoring system is installed within the transfer window body 1. The airflow monitoring component is located upstream and downstream of the airflow channel of the laminar flow air supply component 5. The airflow monitoring component is electrically connected to the embedded control system, and its output is connected to the threshold comparison unit. By setting the airflow monitoring component upstream and downstream of the airflow channel of the laminar flow air supply component 5 and connecting its output to the threshold comparison unit, the airflow signal can participate in the cleanliness risk assessment. The advantage is that the closed-loop system can obtain the combined operating condition input of granularity and airflow at the structural level, providing a data basis for identifying the decline in cleanliness caused by filter blockage, fan abnormality, etc., thereby avoiding delayed detection or misjudgment caused by relying solely on a single granularity indicator, and enhancing the reliability and compliance assurance capability of the pass-through window under long-term operation and equipment aging conditions.

[0025] Furthermore, in sterile or high-cleanliness work environments, operators typically do not want to frequently approach or open equipment to check its status, nor do they want to miss risk warnings due to unclear information. Simultaneously, factors such as cleanroom environmental noise, personnel distribution, and the wearing of protective equipment can reduce the accessibility and identifiability of a single warning method. If a closed-loop system only has internal linkages and lacks clear external visual or audible feedback, it can create a management risk where the system operates without the personnel's awareness, especially prominent in quality systems requiring traceability and rapid response. In one embodiment, the feedback warning module includes an audible and visual alarm and a digital display interface, both electrically connected to a feedback control interface. This limitation restricts the feedback warning module to include an audible and visual alarm and a digital display interface connected to the feedback control interface, enabling the feedback to combine immediate attention capture with transparent status presentation. The advantage is that it can quickly attract attention when there are granular anomalies and intuitively present the current cleanliness or alarm status and equipment status information to the user, improving human-machine interaction efficiency and on-site compliance, and reducing misoperations or delayed handling caused by information asymmetry.

[0026] In scenarios with frequent disturbances such as door opening and closing, and items being placed and taken out, granular signals exhibit obvious transient and fluctuating characteristics. The same peak value may come from short-term turbulent impacts or from continuous dust input. Furthermore, different particle size distributions have different implications for cleanliness levels and pollution sources. If the closed-loop judgment relies solely on whether the instantaneous concentration exceeds the threshold, two problems can easily arise: first, oversensitivity to short-term spikes can lead to false alarms or false triggering; second, insufficient response to continuous upward trends can result in delayed risk identification. To avoid this problem, in one embodiment, the embedded control system includes a trend analysis unit. The input of the trend analysis unit is connected to the data acquisition interface, and the output of the trend analysis unit is connected to the threshold comparison unit. The parameters output by the trend analysis unit include particulate matter concentration change rate, concentration fluctuation, and particle size distribution parameters. By adding a trend analysis unit to the embedded control system and limiting its output to include parameters such as particulate matter concentration change rate, concentration fluctuation, and particle size distribution, and sending them to the threshold comparison unit, the advantage of this design is that the closed-loop system obtains a composite representation capability of "numerical value, trend, and structure" in its structure. This makes the threshold comparison no longer a single-point judgment, but has the conditional basis for identifying "spike disturbances" and "continuous pollution input," thereby reducing false alarms, improving early warning capabilities, and facilitating a more objective and graded assessment of pollution sources or risk levels.

[0027] In actual clean production and experimental scenarios, the acceptable granularity threshold is often strongly correlated with the operating conditions. For example, the door opening phase is an unavoidable disturbance condition; after the door closes and laminar flow recovers, a more stringent judgment should be applied. Similarly, when the airflow is low, even if the granularity does not exceed the limit temporarily, the system may still be in a state of risk accumulation. If a single threshold and a single judgment dimension are still used, the threshold setting will either be too strict, causing frequent alarms, or too lenient, leading to missed risks. Therefore, in one embodiment, the threshold storage unit stores multiple sets of threshold parameters and associates them with influencing factor identifiers. These influencing factor identifiers include door status identifiers and airflow status identifiers. The threshold comparison unit includes a multi-parameter evaluation subunit, whose input is connected to... The system integrates detection data from the particle size monitoring component, parameters output from the trend analysis unit, door status signals from the door status detection component, and airflow signals from the airflow monitoring component. A multi-parameter evaluation subunit outputs multi-level cleanroom risk level signals, with sterilization control and feedback control interfaces connected to these signals. Multiple sets of threshold parameters are stored in a threshold storage unit and associated with influencing factors such as door status and airflow status indicators. A multi-parameter evaluation subunit is also included in the threshold comparison unit. This subunit integrates input particle size data, trend parameters, door status signals, and airflow signals, outputting multi-level cleanroom risk level signals, which are then connected to these risk level signals via the sterilization control and feedback control interfaces. This allows the closed-loop system to select thresholds based on operating conditions and output risk-level signals at the structural level. Sterilization and alerts are upgraded from simple over-limit triggers to risk-driven, condition-adaptive responses, which better aligns with the actual management logic of cleanrooms and significantly improves the precision and stability of closed-loop control.

[0028] In high-precision particle monitoring applications, sensor noise, airflow disturbances, and transient spikes cause particle size data to fluctuate around a threshold. If the judgment logic performs zero hysteresis and zero-time filtering on the threshold, the closed-loop system will exhibit frequent start-stop sterilization or frequent alarm fluctuations. This not only increases the switching losses and lifespan degradation of the sterilization device but also causes frequent operator interference and even reduces sensitivity to actual risks. To address this issue, in one embodiment, the multi-parameter evaluation subunit includes a hysteresis comparator and a continuous over-limit judgment timer. The hysteresis comparator stores the upper and lower thresholds, and the continuous over-limit judgment timer... The device stores the over-limit duration parameter and the recovery stabilization time parameter. A hysteresis comparator and a continuous over-limit judgment timer are added to the multi-parameter evaluation subunit. The hysteresis comparator corresponds to the upper and lower thresholds, and the timer corresponds to the over-limit duration / recovery stabilization time parameter. The upper and lower thresholds form a hysteresis region, which can prevent the output from repeatedly flipping when the signal jitters near the threshold. The time parameter enables the system to distinguish between short-term spikes and continuous over-limits. Structurally, this improves the judgment stability and anti-interference capability, reduces frequent device operation, improves lifespan and user experience, and makes the closed-loop control more engineered and reliable.

[0029] In long-term operation scenarios, the effective output of devices such as ultraviolet lamps and plasma sources will decrease with usage time, contamination accumulation, and aging. Furthermore, the output and drive input of different devices are not necessarily linearly consistent. If the closed-loop system only provides drive commands without receiving feedback on the actual sterilization output, a situation may arise where sterilization appears to have started but the actual dosage is insufficient, leading to an underestimation of cleanliness risks and hindering maintenance and replacement. In one embodiment, the dynamic sterilization component includes a sterilization execution unit, an adjustable drive module, and a sterilization output monitoring component. The input of the adjustable drive module is connected to the sterilization control interface, and its output is connected to the sterilization execution unit. The sterilization output monitoring component is positioned corresponding to the sterilization execution unit and electrically connected to the embedded control system. The output of the sterilization output monitoring component is connected to a threshold comparison unit and the sterilization control interface. The embedded control system also includes a dose accumulation unit, which is connected to the sterilization output monitoring component and the feedback control interface. The dynamic sterilization component is further defined as including a sterilization execution unit, an adjustable drive module, and a sterilization output monitoring component. The output end of the output monitoring component is connected to a threshold comparison unit and a sterilization control interface. A dose accumulation unit is set in the control system and connected to the output monitoring and feedback control interface. The closed loop here not only makes decisions based on granularity, but can also be checked or compensated based on the actual sterilization output, so that the control is improved from a command closed loop to an effect-related closed loop, reducing the hidden risks caused by sterilization decay and improving reliability and compliance. One point that needs further explanation is that the aforementioned dynamic sterilization components typically regulate current. To further achieve targeted sterilization, a dynamic sterilization component is introduced. This component includes a sterilization execution unit mounted on a linear guide or swing arm, and a displacement drive mechanism connected to the guide or swing arm. The displacement drive mechanism can be a lead screw motor. This mechanism drives the sterilization execution unit to extend or swing, changing its irradiation distance or orientation relative to the items within the delivery chamber. When the particle size monitoring component detects severe contamination in a specific area (e.g., with the help of multiple sensors), the control system drives the lead screw motor to extend the sterilization head from a groove in the inner wall of the device, directly approaching the contamination source (e.g., the surface of the delivered item) for targeted sterilization. Here, sterilization is transformed from "static surface irradiation" to "dynamic point-to-point mechanical contact / close-range irradiation," which is highly valuable in medical device delivery.

[0030] In transfer window applications equipped with UV sterilization or other strong treatment methods, particulate matter sensors are prone to drift, aging, or contamination if exposed to radiation, disinfectant wiping, condensation, moisture, and dust for extended periods. Meanwhile, the limited space within the transfer chamber 2 necessitates frequent cleaning and maintenance. The sensor's installation location must ensure both sampling representativeness and durability and maintainability. If sensor drift is not promptly identified, the closed-loop system will trigger sterilization or alarms with erroneous data, leading to misjudgments or missed detections. Relying solely on manual periodic calibration reverts to the drawbacks of manual labor and external sampling in the prior art. Therefore, in one embodiment, the particulate matter sensor is housed in a monitoring chamber isolated from the transfer chamber 2. The monitoring chamber and transfer chamber 2 are connected via a sampling channel, and the monitoring chamber is equipped with a shield against UV radiation and a replaceable breathable protective layer. The dust isolation component and transfer window also include a reference sampling assembly. This assembly includes a reference filter chamber connected to the sampling channel and a sampling switching valve located on the sampling channel. A zero-particle filter is installed within the reference filter chamber. The sampling switching valve is electrically connected to the embedded control system, which includes a sensor health monitoring unit. This unit is connected to the data acquisition interface, the sampling switching valve, and the feedback control interface. By arranging the particulate sensor in a monitoring chamber isolated from the transfer chamber 2, and installing an ultraviolet shield and a replaceable breathable dustproof isolation component within the monitoring chamber, physical isolation from radiation and pollution is achieved. Simultaneously, the addition of the reference sampling assembly and the connection of the sensor health monitoring unit to the data acquisition interface, the switching valve, and the feedback control interface provide the structural basis for the equipment to meet reference conditions. The advantages of this design are: firstly, it significantly reduces the impact of the sterilization environment and dust on sensor stability, extends lifespan, and reduces maintenance frequency; secondly, the reference sampling structure and health monitoring unit provide objective evidence for identifying sensor drift or anomalies, thereby ensuring the long-term reliability of the input data for closed-loop control and ultimately improving the reliability of unmanned monitoring. Following the above embodiments, it was mentioned that the sensor needs to be protected against ultraviolet light, which is achieved by adding shielding components. However, this is static protection and cannot solve the problem of difficult maintenance of the sensor in a polluted environment for a long time. Furthermore, the particle size monitoring component includes a multi-station switching turntable and a drive motor. The multi-station switching turntable is equipped with a detection station and a maintenance station. The detection station is connected to the sampling channel of the transfer chamber for online detection. The maintenance station is connected to the calibration gas path and is correspondingly equipped with a sealed calibration chamber for zero-point calibration or health check. The drive motor is used to drive the multi-station switching turntable to switch between the detection station and the maintenance station, so that the particulate matter sensor can be connected or disconnected from the transfer chamber through physical displacement. This provides physical isolation protection for the sensor under sterilization, cleaning or high humidity conditions and enables automatic maintenance and calibration. The multi-station switching turntable is a rotary indexing turntable or a linear sliding switching slide. The detection station and the maintenance station are respectively equipped with sealing seats that dock with the sampling channel or the calibration gas path. The sealing seats are equipped with sealing rings and positioning structures to ensure airtight connection after switching.

[0031] Working principle and usage process of this invention: During operation, the particle size monitoring component arranged on the sampling channel of the transfer chamber continuously samples the air in the chamber online and transmits the real-time particulate matter concentration data to the embedded control system through the data acquisition interface. The threshold comparison unit inside the control system compares the received data with the preset cleanliness threshold in the threshold storage unit. At the same time, it combines the operating condition signals input by the door status detection component and the air volume monitoring component, as well as the multi-dimensional parameters such as particulate matter change rate and fluctuation provided by the trend analysis unit, to comprehensively assess and classify the current cleanliness risk. Based on the risk assessment results, the embedded control system outputs multiple control commands: on the one hand, it drives the dynamic sterilization component to start and adjust the sterilization intensity, while simultaneously linking the push rod motor to change the angle of the variable guide vane mechanism to optimize airflow organization, achieving rapid dilution and directional removal of pollutants; on the other hand, it issues audible and visual alarms on the outside of the equipment and displays status information on the digital interface through the feedback prompt module. The entire process realizes a complete closed loop from pollution identification, risk assessment, automatic handling to status prompts, enabling the equipment to respond in real time to changes in the cleanliness of the cavity and automatically complete the linkage control of sterilization and airflow adjustment, thereby completely replacing the traditional manual inspection and external sampling inspection mode.

[0032] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present invention. Any simple modifications, equivalent changes and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A self-monitoring germicidal laminar flow delivery window characterized by, The delivery window body is provided with a delivery cavity, and a first opening and closing door and a second opening and closing door are arranged on opposite sides of the delivery cavity respectively; a laminar flow air supply assembly is arranged in the delivery window body, the laminar flow air supply assembly is provided with an air supply outlet which is communicated with the delivery cavity and is arranged towards the delivery cavity; a variable guide vane mechanism is arranged at the air supply outlet of the laminar flow air supply assembly, the variable guide vane mechanism comprises a guide vane which is driven by a push rod motor, and the push rod motor drives the guide vane to change the angle through a connecting rod mechanism so as to change the air flow organization in the delivery cavity; A particle size monitoring assembly is arranged on a sampling channel which is communicated with the delivery cavity, the particle size monitoring assembly comprises a multi-station switching turntable, the turntable comprises a detection station which is communicated with the delivery cavity and a maintenance station which is communicated with a calibration gas path; and a displacement driving motor is arranged for driving the turntable to switch between the detection station and the maintenance station, so that the particulate matter sensor is communicated with the sampling channel when in the detection station and is communicated with the calibration gas path and is physically disconnected from the delivery cavity when in the maintenance station; a dynamic sterilization assembly is arranged in an air flow channel of the laminar flow air supply assembly; a feedback prompt module is arranged outside the delivery window body; and an embedded control system is arranged in the delivery window body, and the embedded control system is electrically connected with the particle size monitoring assembly, the dynamic sterilization assembly, the feedback prompt module, the displacement driving motor and the push rod motor respectively; The embedded control system comprises a data acquisition interface, a threshold storage unit and a threshold comparison unit, the data acquisition interface is connected with the particle size monitoring assembly, the input end of the threshold comparison unit is connected with the data acquisition interface and the threshold storage unit; and the embedded control system outputs a control signal according to the particle size data to drive the displacement driving motor and the push rod motor to act, so as to realize the linkage control of the particle size monitoring and the air flow organization adjustment, and the feedback prompt module is driven to give a prompt when the particle size exceeds the limit.

2. A self-monitoring germicidal laminar flow delivery window according to claim 1, wherein, The particle size monitoring assembly comprises at least one particulate matter sensor and a sampling channel which is communicated with the particulate matter sensor, the air inlet end of the sampling channel is opened in the delivery cavity and is arranged along the main direction of the air flow which is pointed by the air supply outlet, and a steady flow cavity, a flow limiting piece and a micro sampling pump are arranged on the sampling channel.

3. A self-monitoring germicidal laminar flow delivery window according to claim 1 wherein, The first opening and closing door and the second opening and closing door are respectively provided with a door state detection assembly, the door state detection assembly is electrically connected with the embedded control system, and the output end of the door state detection assembly is connected with the threshold comparison unit.

4. A self-monitoring germicidal laminar flow delivery window according to claim 1 wherein, A wind volume monitoring assembly is arranged in the delivery window body, the wind volume monitoring assembly is arranged at upstream and downstream positions of the air flow channel of the laminar flow air supply assembly, the wind volume monitoring assembly is electrically connected with the embedded control system, and the output end of the wind volume monitoring assembly is connected with the threshold comparison unit.

5. A self-monitoring germicidal laminar flow delivery window according to claim 1 wherein, The feedback prompt module comprises an audible and visual alarm and a digital display interface, and the audible and visual alarm and the digital display interface are electrically connected with a feedback control interface.

6. A self-monitoring germicidal laminar flow delivery window according to claim 1 wherein, The embedded control system includes a trend analysis unit. The input of the trend analysis unit is connected to a data acquisition interface, and the output of the trend analysis unit is connected to a threshold comparison unit. The parameters output by the trend analysis unit include particulate matter concentration change rate parameters, concentration fluctuation parameters, and particle size distribution parameters.

7. A self-monitoring germicidal laminar flow delivery window according to claim 6 wherein, The threshold storage unit stores multiple sets of threshold parameters and associates them with influencing factor identifiers. The influencing factor identifiers include door status identifiers and airflow status identifiers. The threshold comparison unit includes a multi-parameter evaluation subunit. The input of the multi-parameter evaluation subunit is connected to at least the detection data of the particle size monitoring component, the parameters output by the trend analysis unit, the door status signal of the door status detection component, and the airflow signal of the airflow monitoring component. The multi-parameter evaluation subunit outputs multi-level cleanliness risk level signals, and the sterilization control interface and the feedback control interface are respectively connected to the cleanliness risk level signals.

8. A self-monitoring germicidal laminar flow delivery window according to claim 7 wherein, The multi-parameter evaluation subunit includes a hysteresis comparator and a continuous over-limit determination timer. The hysteresis comparator stores an upper threshold and a lower threshold, and the continuous over-limit determination timer stores an over-limit duration parameter and a recovery stabilization time parameter.

9. A self-monitoring germicidal laminar flow delivery window according to claim 1 wherein, The dynamic sterilization component includes a sterilization execution unit, an adjustable drive module, and a sterilization output monitoring component. The input end of the adjustable drive module is connected to the sterilization control interface, and its output end is connected to the sterilization execution unit. The sterilization output monitoring component is located at a position corresponding to the sterilization execution unit and is electrically connected to the embedded control system. The output end of the sterilization output monitoring component is connected to the threshold comparison unit and the sterilization control interface. The embedded control system also includes a dose accumulation unit, which is connected to the sterilization output monitoring component and the feedback control interface.

10. A self-monitoring germicidal laminar flow delivery window according to claim 2 wherein, The particulate sensor is disposed in a monitoring cavity isolated from the transfer cavity. The monitoring cavity is connected to the transfer cavity through the sampling channel. The monitoring cavity is equipped with a shield against ultraviolet radiation and a replaceable breathable and dustproof isolation component. The transfer window also includes a reference sampling assembly, which includes a reference filter cavity connected to the sampling channel and a sampling switching valve disposed on the sampling channel. The reference filter cavity is equipped with a zero-particle filter. The sampling switching valve is electrically connected to the embedded control system. The embedded control system includes a sensor health monitoring unit, which is connected to the data acquisition interface, the sampling switching valve, and the feedback control interface.

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