An implantable wireless blood pressure monitoring device

Abstract

The application provides an implantable wireless blood pressure monitoring device, and relates to the field of implantable monitoring devices.The device comprises a hard rubber support, a pressure-sensitive chip, an inductor coil and a support wire.The pressure-sensitive chip is fixed to one side of the hard rubber support, with its detection end exposed to the surface of the hard rubber support.The inductor coil is fixed to one side of the hard rubber support and coupled with the pressure-sensitive chip, used for receiving wireless power supply from an external device and wirelessly transmitting the electrical signal monitored by the pressure-sensitive chip to the external device.The support wire is provided with two support wires fixed to the two sides of the hard rubber support, used for supporting and fixing the hard rubber support in the blood vessel.The technical scheme has the advantages of compact overall structure, good biocompatibility, high-precision sensing, passive power supply, stable fixation and minimally invasive implantation, and significantly improves the long-term reliability and clinical practicability of the implantable blood pressure monitoring.

Description

Technical Field

[0001] This invention generally relates to the field of implantable monitoring devices, and more specifically to an implantable wireless blood pressure monitoring device. Background Technology

[0002] Hypertension is a significant risk factor for cardiovascular disease, and accurate, long-term monitoring is crucial for disease prevention, optimization of treatment plans, and patient health management. With the development of medical technology, various blood pressure monitoring technologies have emerged in clinical and daily settings. However, due to limitations in technical principles and structural design, existing solutions all have insurmountable shortcomings and cannot meet patients' needs for long-term, continuous, accurate, safe, and minimally invasive blood pressure monitoring.

[0003] Currently, mainstream blood pressure monitoring technologies mainly fall into three categories: The first category is traditional blood pressure monitor technology. This technology involves medical staff operating the monitor or patients using it themselves to take single-point or intermittent blood pressure measurements and manually recording the data for long-term blood pressure tracking and management. However, the measurement results of this type of technology are easily affected by various external factors such as patient emotional fluctuations, measurement posture, and operational standardization, resulting in poor accuracy. Furthermore, the measurement process is intermittent, making it impossible to capture dynamic blood pressure changes in the patient's daily life and reflect the true pattern of blood pressure fluctuations, thus limiting clinical diagnosis and treatment planning.

[0004] The second type is ambulatory blood pressure monitoring (ABPM), which uses a fully automated, non-invasive measurement method to continuously or intermittently record the patient's blood pressure data at preset time intervals. It can provide a 24-hour blood pressure change curve, which helps to assess blood pressure fluctuation characteristics and treatment effects. However, this technology relies on a monitoring device worn on the patient's body. The device is bulky and inconvenient to wear, which can significantly affect the patient's daily activities (such as sleep and exercise), leading to low patient compliance and resistance. At the same time, due to limitations such as device battery life and wearing comfort, its monitoring time is usually limited to no more than 24 hours, which cannot achieve long-term, continuous blood pressure monitoring and cannot meet the long-term management needs of patients with chronic hypertension or special diseases such as heart failure.

[0005] The third category is interventional blood pressure monitoring technology. This technology involves inserting a detection component through an arterial cannula into the target location within the body via minimally invasive surgery to directly measure intravascular blood pressure. Compared to the first two non-invasive technologies, it offers higher accuracy and provides continuous readings, making it valuable in intensive care or some surgical procedures. However, existing interventional technologies still have significant drawbacks: Firstly, although it is a minimally invasive procedure, traditional interventional devices are relatively large or complex in structure, resulting in relatively noticeable surgical wounds and strong mechanical stimulation of the blood vessel walls. This not only increases the risk of complications and wound infection due to improper operation but also causes additional trauma to the patient. Secondly, the related equipment and operating costs are high, and the detection components are usually disposable, enabling only short-term monitoring and failing to meet the long-term continuous monitoring needs of patients with chronic diseases, severely limiting its application scenarios. Furthermore, this type of technology requires operation by professional medical personnel, but the complexity of traditional methods further increases medical costs and risks.

[0006] In summary, among existing blood pressure monitoring technologies, non-invasive techniques struggle to balance accuracy and continuity, while traditional interventional techniques, although capable of ensuring short-term measurement accuracy, suffer from relatively large trauma, high safety risks, high costs, and the inability to perform long-term monitoring. Even though the objective prerequisite of requiring professional operation cannot be avoided, their core defects remain unresolved and fail to meet the clinical core needs for "long-term, continuous, accurate, safe, and low-invasive" blood pressure monitoring. Summary of the Invention

[0007] In view of the problems existing in the prior art, the present invention provides an implantable wireless blood pressure monitoring device, comprising: a rigid plastic support body; a pressure-sensitive chip, the pressure-sensitive chip being fixed to one side of the rigid plastic support body with its detection end exposed on the surface of the rigid plastic support body; an inductor coil, the inductor coil being fixed to one side of the rigid plastic support body and coupled to the pressure-sensitive chip, for receiving wireless power from an external device and wirelessly transmitting the electrical signal monitored by the pressure-sensitive chip to the external device; and two support wires, the support wires being provided and fixed to both sides of the rigid plastic support body for supporting and fixing the rigid plastic support body within the blood vessel.

[0008] With the aforementioned technical features, this implantable wireless blood pressure monitoring device directly exposes the pressure-sensitive chip's detection end to the surface of a rigid plastic support, ensuring real-time and accurate sensing of intravascular blood pressure changes. The inductor coil, coupled with the pressure-sensitive chip, not only receives radio frequency energy emitted by the external device for wireless power supply, eliminating the need for a built-in battery and avoiding battery life limitations and replacement surgery risks, but also efficiently transmits the electrical signals output by the pressure-sensitive chip wirelessly to the external device, enabling long-term continuous monitoring. Simultaneously, the support wires on both sides of the device automatically unfold within the blood vessel and gently conform to the vessel wall, providing stable and reliable radial support and axial positioning, effectively preventing displacement, rotation, or detachment of the device under blood flow impact. The overall structure is compact and biocompatible, combining the advantages of high-precision sensing, passive power supply, stable fixation, and minimally invasive implantation, significantly improving the long-term reliability and clinical applicability of implantable blood pressure monitoring.

[0009] In some embodiments, the pressure-sensitive chip is fixed within the annular region of the inductor coil. This layout effectively achieves a high degree of integration between the sensing unit and the wireless power supply or communication unit. By embedding the pressure-sensitive chip into the central cavity of the inductor coil, not only is the overall radial dimension of the device significantly reduced, facilitating minimally invasive delivery and implantation in narrow blood vessels, but the electromagnetic coupling efficiency is also optimized—the alternating magnetic field generated by the inductor coil is relatively uniform in the central region, providing a more stable inductive power supply environment for the chip. Simultaneously, this compact arrangement shortens the length of the connecting wires between the chip and the coil, reducing parasitic capacitance and noise interference in the signal transmission path, and improving the signal-to-noise ratio and reliability of blood pressure signal acquisition and wireless transmission. Furthermore, the annular coil forms a physical enclosure around the central chip, which can protect the sensitive element from direct blood flow or mechanical damage to a certain extent, thereby enhancing the stability and durability of the device during long-term implantation.

[0010] In some embodiments, a soft encapsulation shell is also included, which seals over the rigid support. Thus, this design forms a continuous, dense protective layer using a soft, elastic, and biocompatible encapsulation material, effectively isolating the internal electronic components, including the pressure-sensitive chip and inductor coil, from the corrosive effects of bodily fluids, significantly improving the long-term sealing and reliability of the device. Simultaneously, the flexible surface of the soft encapsulation shell can adapt to the dynamic deformation of the blood vessel wall, providing cushioning when the device contacts the inner wall of the blood vessel, reducing the risk of endothelial damage, inflammatory reactions, or thrombosis caused by friction or pressure from rigid structures. Furthermore, this encapsulation layer further smooths the outer contour of the device, reduces blood flow disturbance, improves blood compatibility, and enhances the fatigue resistance of the overall structure, thereby ensuring the long-term, stable, and safe operation of the implantable wireless blood pressure monitoring device in complex physiological environments.

[0011] In some embodiments, the dimensions of the soft encapsulation shell do not exceed 20*5*3mm to adapt to the intravascular space and allow for implantation via minimally invasive surgery. This compact, miniaturized design fully considers the space constraints of intravascular implantation and the clinical needs of minimally invasive surgery. Such a small size allows the device to be successfully delivered percutaneously to target vascular sites such as the coronary arteries, carotid arteries, or peripheral arteries via a catheter system, significantly reducing damage to the vessel wall and surgical trauma. Simultaneously, the small size effectively reduces its occupancy effect and fluid resistance in blood flow, avoiding significant hemodynamic disturbances or turbulence, thereby reducing the risk of thrombosis and vascular irritation. This size specification, while ensuring reliable integration of internal functional components including the pressure-sensitive chip and inductor coil, achieves good compatibility between the implant and vascular anatomy, providing a feasible engineering basis for long-term, safe, and minimally invasive wireless blood pressure monitoring.

[0012] In some embodiments, two support wires are symmetrically arranged on both sides of the rigid plastic support, with each end fixedly connected to the rigid plastic support. This symmetrical arrangement ensures balanced force distribution within the blood vessel, uniformly transmitting support force to both sides of the vessel wall and effectively preventing deflection, rotation, or axial displacement of the device under blood flow impact. Simultaneously, the fixed-end design enhances the reliability of the connection between the support wires and the rigid plastic support, avoiding stress concentration or fatigue fracture caused by single-point connections, thus improving the overall mechanical durability. Furthermore, this double-ended, arched design can adaptively conform to the inner walls of blood vessels of different diameters after release, providing gentle and continuous radial support force. This ensures stable device positioning while avoiding localized pressure that could damage the vascular endothelium, thereby balancing implantation stability and biosafety, providing a reliable physical basis for long-term blood pressure monitoring.

[0013] In some embodiments, the support wire forms an arc-shaped elastic support portion on the side away from the rigid adhesive support. This allows the structure to gently and stably conform to the inner wall of the blood vessel after implantation, thanks to its inherent elastic deformation capability. The arc-shaped design not only provides uniformly distributed radial support force, effectively preventing displacement or overturning of the device under blood flow impact, but also avoids damage or irritation to the vascular endothelium caused by sharp or rigid contact points; simultaneously, the elastic support portion has good compliance, adapting to the anatomical shape of blood vessels of different diameters, and dynamically deforming with the vessel wall during cardiac pulsation or vasoconstriction, maintaining a continuous and stable anchoring effect.

[0014] In some embodiments, each support wire is provided with an elastic support assembly, which includes a reinforcing wire located within the space formed by the support wire; and two sleeves, each fixed to one end of the support wire and sleeved onto the support wire, sliding along the length of the support wire. Thus, this structure mechanically reinforces the internal space of the support wire through the reinforcing wire, significantly improving the compressive and flexural strength of the support while maintaining overall flexibility, preventing the device from collapsing or deforming under external pressure within the blood vessel. The slidable sleeves at both ends serve as dynamic constraint nodes, allowing for local fine-tuning during support wire deployment or deformation with the blood vessel, effectively alleviating stress concentration and avoiding fatigue fracture caused by rigid connections. Furthermore, the synergistic effect of the sliding sleeves and reinforcing wires enables the elastic support assembly to provide stable radial support while possessing good adaptability and buffering performance. It can firmly anchor the device position while conforming to vascular pulsation and bending, thus ensuring both mechanical reliability and biocompatibility for long-term implantation, providing strong support for the stable operation of wireless blood pressure monitoring.

[0015] In some embodiments, both the reinforcing wire and the supporting wire are made of highly elastic nitinol alloy. This material possesses excellent superelasticity and shape memory properties, enabling it to withstand repeated large deformations in the complex mechanical environment of blood vessels without permanent plastic damage. The consistency of the two materials not only ensures coordinated deformation and uniform stress distribution at body temperature, avoiding interfacial stress concentration or fatigue failure due to differences in material stiffness, but also allows the entire support structure to stably recover its preset three-dimensional shape after release, providing continuous, gentle, and reliable radial support. Simultaneously, the excellent biocompatibility and corrosion resistance of nitinol alloy further enhance the safety and durability of long-term implantation of the device, effectively ensuring the stability and reliability of the wireless blood pressure monitoring function in dynamic vascular environments.

[0016] In some embodiments, the surfaces of the support wire and the reinforcing wire are coated with an anticoagulant coating. This coating effectively inhibits platelet adhesion and coagulation cascade reactions when blood comes into contact with the material surface, significantly reducing the risk of thrombosis. Since the support wire and reinforcing wire are directly exposed to the intravascular blood flow environment, the anticoagulant treatment not only improves the device's blood compatibility but also reduces complications such as vascular occlusion, distal embolism, or inflammatory reactions caused by thrombus adhesion. Simultaneously, the coating helps maintain the smoothness and bioinertness of the device surface, preventing fibrin sheath encapsulation or tissue proliferation caused by coagulation activation during long-term implantation, thereby ensuring stable sensor positioning and signal acquisition accuracy.

[0017] In some embodiments, the reinforcing wire is an arc-shaped filament that bends in the same direction as the elastic support. This unidirectional arc structure not only enhances the overall rigidity of the support but also allows the elastic support to bend in a coordinated manner along its natural curvature when subjected to external pressures such as blood vessel wall compression or blood flow impact, preventing unintended twisting or overturning. Because the bending direction is unconstrained and follows its predetermined arc path, the contact area between the support wire and the blood vessel wall is appropriately expanded, forming a more uniform surface contact rather than point contact, thereby effectively dispersing local pressure and reducing the risk of mechanical damage to the vascular endothelium. Simultaneously, this controllable elastic deformation behavior has both "elasticity enhancement" and "positioning" functions: on the one hand, it provides continuous rebound force through the material's hyperelasticity, maintaining stable device fit; on the other hand, it achieves adaptive anchoring by expanding the contact area, preventing device slippage or rotation. Overall, this design significantly optimizes biocompatibility and long-term implantation safety while improving structural reliability.

[0018] It should be understood that the description in the Summary of the Invention is not intended to limit the key or essential features of the embodiments of this disclosure, nor is it intended to restrict the scope of this disclosure. Other features of this disclosure will become readily apparent from the following description. Attached Figure Description

[0019] Figure 1 A schematic diagram of the overall structure of an implantable wireless blood pressure monitoring device according to an embodiment of the present invention is shown. Figure 2 An exploded structural diagram of an implantable wireless blood pressure monitoring device according to an embodiment of the present invention is shown; Figure 3 A schematic diagram of the elastic support component in an implantable wireless blood pressure monitoring device according to an embodiment of the present invention is shown.

[0020] Symbol Explanation 1. Soft plastic encapsulation shell; 2. Hard plastic support body; 3. Pressure-sensitive chip; 4. Inductor coil; 5. Support wire; 51. Elastic support part; 6. Elastic support assembly; 61. Reinforcing wire; 62. Sleeve. Detailed Implementation

[0021] The preferred embodiments (or implementation methods) of the present invention will now be described in detail with reference to the accompanying drawings.

[0022] The following is for reference. Figures 1-3 This invention describes an implantable wireless blood pressure monitoring device.

[0023] Figure 1 A schematic diagram of the overall structure of an implantable wireless blood pressure monitoring device according to an embodiment of the present invention is shown. (Reference) Figure 1As shown, an implantable wireless blood pressure monitoring device includes: a rigid plastic support 2, a pressure-sensitive chip 3, an inductor coil 4, and support wires 5. The pressure-sensitive chip 3 is fixed to one side of the rigid plastic support 2, with its detection end exposed on the surface of the rigid plastic support 2. The inductor coil 4 is fixed to one side of the rigid plastic support 2 and coupled to the pressure-sensitive chip 3, for receiving wireless power from an external device and wirelessly transmitting the electrical signal data monitored by the pressure-sensitive chip 3 to the external device. Two support wires 5 are provided and fixed to both sides of the rigid plastic support 2 for supporting and fixing the rigid plastic support 2 within the blood vessel.

[0024] The rigid support 2 is a rigid base made of biocompatible polymer materials such as PEEK or medical epoxy resin, used to integrate and fix various functional components. Its compact shape provides structural support for the entire miniaturized device. The pressure-sensitive chip 3 is a capacitive pressure sensor manufactured using microelectromechanical systems (MEMS) technology. It is fixed to one side of the rigid support 2, with its detection end directly exposed on the surface of the support. It can accurately sense changes in intravascular pressure and has high sensitivity and anti-interference capabilities. The inductor coil 4 is an electromagnetic coupling element made of conductive wire. It is fixed to one side of the rigid support 2 and electrically connected to the pressure-sensitive chip 3, forming a wireless power supply and communication unit. It receives radio frequency energy emitted by the external device to achieve battery-free power supply in the body and wirelessly transmits the blood pressure electrical signal collected by the pressure-sensitive chip 3 to the external device after modulation. The support wire 5 consists of two slender components symmetrically arranged on both sides of the rigid support 2. It is usually made of high-elasticity nickel-titanium alloy with an anticoagulant coating on the surface. After implantation into the blood vessel, it can adaptively unfold and gently conform to the vessel wall to achieve stable anchoring and positioning of the device.

[0025] Based on the organic integration of the above functional modules, this invention constructs a highly collaborative implantable monitoring system. The rigid adhesive support 2, as the core carrier, not only ensures the rational spatial layout of the pressure-sensitive chip 3 and the inductor coil 4, but also provides a structural basis for miniaturization design. The exposed surface design of the pressure-sensitive chip 3 allows it to directly respond to blood flow pressure fluctuations, and combined with MEMS technology, ensures the accuracy and stability of long-term measurements. The inductor coil 4 opens up the energy and information channels between the inside and outside of the body, freeing the device from battery constraints and enabling true long-term service capability. The support wires 5 with anticoagulant coatings on both sides not only provide mechanical anchoring but also reduce the risk of thrombosis through biocompatible surface treatment. Overall, this device is no longer just a single-function sensor, but an intelligent monitoring platform integrating precise sensing, wireless interaction, adaptive fixation, and biosafety. It can meet the clinical need for continuous blood pressure data and achieve remote management, abnormal warnings, and doctor-patient data sharing through portable external devices, significantly improving the efficiency of cardiovascular chronic disease management and patients' quality of life.

[0026] Figure 2An exploded structural diagram of an implantable wireless blood pressure monitoring device according to an embodiment of the present invention is shown. (Reference) Figure 2 As shown, the pressure-sensitive chip 3 is fixed within the annular region of the inductor coil 4. The annular region refers to the internal cavity or opening formed at the geometric center of the inductor coil 4 after winding. Fixing the pressure-sensitive chip 3 within the annular region of the inductor coil 4 achieves a high degree of integration and space optimization between the sensing unit and the wireless power supply and communication unit. This layout makes full use of the unused space at the center of the inductor coil 4, effectively reducing the overall outline size of the device, which is beneficial for minimally invasive implantation and deployment in narrow blood vessels. At the same time, the pressure-sensitive chip 3 is located in the relatively uniform central region of the coil's magnetic field, which provides a more stable inductive power supply environment and reduces power supply fluctuations caused by positional offset. In addition, the electrical connection path between the chip and the coil is shortened, reducing parasitic interference and energy loss during signal transmission, and improving the signal-to-noise ratio of blood pressure signal acquisition and the reliability of wireless transmission. This structural design not only enhances the synergy between functional modules but also provides strong support for the miniaturization, high integration, and long-term stable operation of the device.

[0027] In some embodiments, an implantable wireless blood pressure monitoring device further includes a soft encapsulation shell 1, which seals over the rigid support body 2. The soft encapsulation shell 1 refers to an outer covering structure made of flexible polymer materials such as medical silicone or polyurethane, which completely seals over the entire rigid support body 2, forming a continuous and dense barrier with good elasticity, biocompatibility, and long-term stability.

[0028] By fully encapsulating the rigid rubber support 2 with a soft rubber encapsulation shell 1, the device significantly improves overall biocompatibility and long-term implantation safety while maintaining the rigidity and functional integrity of its internal structure. The flexible surface of the soft rubber encapsulation shell 1 effectively buffers the mechanical contact between the device and the inner wall of the blood vessel, avoiding endothelial damage, inflammatory reactions, or thrombosis caused by friction or pressure from hard edges. Simultaneously, its dense sealing properties prevent the penetration and erosion of internal electronic components by blood, tissue fluid, and other bodily fluids, ensuring the long-term electrical performance stability of the pressure-sensitive chip 3 and the inductor coil 4 in complex physiological environments. Furthermore, the conformability of the soft rubber material allows it to deform naturally with vascular pulsation, reducing foreign body sensation and localized stress concentration, further enhancing the device's durability and reliability in dynamic vascular environments. This provides crucial structural support for achieving long-term, continuous, and safe wireless blood pressure monitoring.

[0029] In some embodiments, the length, width, and height of the soft encapsulation shell 1 do not exceed 20*5*3mm to adapt to the intravascular space and allow for implantation via minimally invasive surgery. In one embodiment, the overall dimensions of the soft encapsulation shell 1 are 16*4.5*2.5mm. By controlling the external dimensions of the soft encapsulation shell 1 within a micro-range suitable for the intravascular lumen, the device can be successfully implanted into the target vascular site via a catheter system through minimally invasive intervention, significantly reducing surgical trauma and interference with the vascular structure. The compact size effectively reduces the space-occupying effect in blood flow, avoiding significant hemodynamic disturbances or turbulence, thereby reducing the risk of thrombosis and vascular irritation; at the same time, the small size design makes the device suitable for various diameter peripheral or coronary arteries and other stenotic anatomical environments, expanding the scope of clinical application. Under the premise of ensuring reliable integration of internal functional components, this miniaturized encapsulation not only improves the feasibility and safety of the implantation process, but also provides a guarantee for postoperative patient comfort and long-term in vivo tolerance, and is an important structural basis for realizing long-term, stable, wireless blood pressure monitoring.

[0030] In some embodiments, two support wires 5 are symmetrically arranged on both sides of the rigid plastic support 2, and their ends are fixedly connected to the rigid plastic support 2. By symmetrically arranging the two support wires 5 on both sides of the rigid plastic support 2 and fixing both ends to the rigid plastic support 2, this structure forms a balanced and highly stable anchoring mechanism within the blood vessel. The symmetrical layout ensures that the device is not easily deflected or rotated under the impact of blood flow, while the double-end fixing method significantly enhances the connection strength between the support wires 5 and the main body, avoiding stress concentration or fatigue fracture caused by single-point connection. This design allows the support wires 5 to form a stable arc or annular profile after release, uniformly transmitting the support force to both sides of the blood vessel wall, providing reliable radial support while effectively preventing axial displacement or overturning of the device.

[0031] In some embodiments, such as Figure 1As shown, an arc-shaped elastic support portion 51 is formed on the side of the support wire 5 away from the rigid plastic support 2. The arc-shaped elastic support portion 51 refers to the smooth, curved section formed by the support wire 5 on the side away from the rigid plastic support 2. This portion has good flexibility and resilience, and can undergo reversible deformation under stress. After implantation into a blood vessel, the device can gently and uniformly conform to the inner wall of the blood vessel. This arc-shaped structure provides radial support while exhibiting excellent compliance, adaptively adjusting its shape according to the pulsation, bending, or diameter changes of the blood vessel, avoiding localized compression or endothelial damage caused by rigid contact. When subjected to external pressure, the elastic support portion 51 bends along its preset arc, expanding the contact area with the blood vessel wall, thereby dispersing stress, enhancing anchoring stability, and effectively limiting the displacement or rotation of the device. Furthermore, the arc-shaped design itself has good fatigue resistance, maintaining structural integrity under long-term cyclic loading, ensuring the device operates reliably and persistently in dynamic vascular environments, providing a solid mechanical guarantee for the stable operation of wireless blood pressure monitoring.

[0032] Figure 3 A schematic diagram of the elastic support component 6 in an implantable wireless blood pressure monitoring device according to an embodiment of the present invention is shown. (Refer to...) Figure 3 As shown, each support wire 5 is provided with an elastic support component 6. The elastic support component 6 includes a reinforcing wire 61 and a sleeve 62. The reinforcing wire 61 is located in the space formed by the support wire 5. There are two sleeves 62, which are respectively fixed to the two ends of the reinforcing wire 61 and sleeved on the support wire 5, and slide along the length direction of the support wire 5.

[0033] The elastic support component 6 is an auxiliary reinforcement structure set on a single support wire 5 to improve its mechanical properties and stability; the reinforcing wire 61 is another highly elastic metal wire arranged in the internal space enclosed by the bending of the support wire 5 itself, which plays a role in enhancing stiffness and resistance to buckling; the sleeve 62 is a small tubular component made of biocompatible material, two of which are fixed to the two ends of the reinforcing wire 61 respectively, and are slidably sleeved on the support wire 5, allowing relative movement along the length of the support wire 5.

[0034] This device significantly improves the mechanical reliability of local structures while maintaining overall flexibility. The reinforcing wire 61, located within the arc-shaped space formed by the support wire 5, effectively resists collapse or unexpected deformation caused by external pressure, enhancing the compressive and flexural strength of the support. The sliding sleeve 62, fixed at both ends to the reinforcing wire 61 and fitted onto the support wire 5, forms a dynamic connection mechanism between the reinforcing wire 61 and the support wire 5, allowing relative sliding during stress, thereby releasing local stress and preventing fatigue damage caused by rigid constraints. This structure enables the support wire 5 to maintain a stable preset shape after deployment within the blood vessel, while also possessing sufficient compliance to adapt to vascular pulsation and anatomical changes, balancing anchoring stability and biosafety, providing a reliable mechanical support foundation for the long-term stable operation of the implantable wireless blood pressure monitoring device.

[0035] In some embodiments, both the reinforcing wire 61 and the supporting wire 5 are made of high-elasticity nitinol alloy. High-elasticity nitinol alloy is a nickel-titanium-based shape memory alloy with superelasticity and good biocompatibility, capable of recovering its original shape without residual strain after large deformation, and is widely used in implantable medical devices. This device achieves a high degree of synergy between material properties and consistency in structural response. Both materials have similar superelastic moduli and recovery characteristics at body temperature, ensuring synchronized and coordinated movement during deformation under intravascular stress, avoiding interfacial stress concentration, local fatigue, or connection failure due to differences in material stiffness. Simultaneously, the excellent fatigue resistance and corrosion resistance of nitinol alloy significantly improve the reliability and durability of the entire support structure under long-term dynamic loads. Furthermore, the uniform material simplifies the manufacturing process and ensures the predictability and stability of the device's deformation behavior during repeated compression delivery and in vivo deployment, thus providing a solid material and structural foundation for the long-term safe anchoring and accurate sensing of implantable wireless blood pressure monitoring devices in complex vascular environments.

[0036] In some embodiments, the surfaces of the support wire 5 and the reinforcing wire 61 are provided with an anticoagulant coating. The anticoagulant coating refers to a layer of biocompatible functional material, such as a heparinized coating, phosphocholine polymer, or other blood-compatible polymer, coated on the surface of the aforementioned metal wire. Its function is to inhibit platelet adhesion and reduce the activation of coagulation factors, thereby reducing the risk of thrombosis.

[0037] This device significantly improves its blood compatibility for long-term intravascular implantation. Since the support structure is directly exposed to the blood flow environment, the anticoagulant coating effectively blocks non-specific interactions between the material surface and blood components, inhibiting platelet aggregation and fibrin deposition, thereby greatly reducing the probability of local thrombosis, embolism, or vascular inflammation. Simultaneously, the smooth, inert interface formed by the coating reduces irritation to the vascular endothelium, helping to maintain the normal physiological state of the vessel wall. This design not only enhances the device's safety but also avoids deterioration of the support function or sensor signal interference caused by thrombus encapsulation, providing crucial biointerface protection for achieving long-term, stable, and reliable wireless blood pressure monitoring.

[0038] In some embodiments, the reinforcing wire 61 is an arc-shaped filament that bends in the same direction as the elastic support 51. In a static state without external force, the reinforcing wire 61 and the support wire 5 are arranged coplanarly, effectively reducing the overall lateral profile and space occupation within the blood vessel. This facilitates minimally invasive delivery of the device via catheter and reduces interference with blood flow after implantation. When the device is subjected to external pressure within the blood vessel, such as pressure from the vessel wall or blood flow impact, the reinforcing wire 61, due to its pre-designed co-directional arc-shaped structure, preferentially undergoes controllable bending, protruding beyond the plane of the support wire 5, thereby actively expanding the support area and enhancing local stiffness. This dynamic response mechanism not only improves pressure resistance and structural stability, preventing support collapse and failure, but also disperses pressure by expanding the contact area with the vessel wall, reducing concentrated pressure on the vascular endothelium. It balances low invasiveness, high reliability, and good biocompatibility, providing an optimized mechanical support scheme for stable blood pressure monitoring in long-term implantation environments.

[0039] In the description of this specification, the terms "connection," "installation," and "fixing," etc., should be interpreted broadly. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0040] The above are merely preferred embodiments of this application and are not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. An implantable wireless blood pressure monitoring device, characterized in that, include: Rigid plastic support (2), Pressure-sensitive chip (3), the pressure-sensitive chip (3) is fixed to one side of the rigid plastic support (2), and its detection end is exposed on the surface of the rigid plastic support (2); Inductor coil (4), the inductor coil (4) is fixed to one side of the hard plastic support (2) and coupled to the pressure-sensitive chip (3), for receiving wireless power supply from the external device and wirelessly transmitting the electrical signal data monitored by the pressure-sensitive chip (3) to the external device; as well as Support wire (5), two of which are fixed on both sides of the rigid plastic support (2) for supporting and fixing the rigid plastic support (2) in the blood vessel.

2. The implantable wireless blood pressure monitoring device according to claim 1, characterized in that, The pressure-sensitive chip (3) is fixed within the annular region of the inductor coil (4).

3. An implantable wireless blood pressure monitoring device according to claim 1 or 2, characterized in that, It also includes a soft rubber encapsulation shell (1), which seals and covers the hard rubber support (2).

4. An implantable wireless blood pressure monitoring device according to claim 3, characterized in that, The length, width and height of the soft rubber encapsulation shell (1) shall not exceed 20*5*3mm, so as to fit the intravascular space and be implanted through minimally invasive surgery.

5. An implantable wireless blood pressure monitoring device according to claim 1, characterized in that, Two support wires (5) are symmetrically arranged on both sides of the rigid plastic support (2), and their two ends are fixedly connected to the rigid plastic support (2).

6. An implantable wireless blood pressure monitoring device according to claim 5, characterized in that, The support wire (5) forms an arc-shaped elastic support part (51) on the side away from the hard plastic support (2).

7. An implantable wireless blood pressure monitoring device according to claim 6, characterized in that, Each of the support wires (5) is provided with an elastic support assembly (6), the elastic support assembly (6) including... A reinforcing wire (61) is located within the space formed by the supporting wire (5); Sleeves (62), two sleeves (62) are provided, which are respectively fixed to the two ends of the reinforcing wire (61) and sleeved on the support wire (5), and slide along the length direction of the support wire (5).

8. An implantable wireless blood pressure monitoring device according to claim 7, characterized in that, Both the reinforcing wire (61) and the supporting wire (5) are made of high-elasticity nickel-titanium alloy.

9. An implantable wireless blood pressure monitoring device according to claim 7 or 8, characterized in that, The surfaces of the support wire (5) and the reinforcing wire (61) are provided with an anticoagulant coating.

10. An implantable wireless blood pressure monitoring device according to claim 7, characterized in that, The reinforcing wire (61) is an arc-shaped wire and bends in the same direction as the elastic support (51).

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