A rapid experimental drug concentration measuring instrument

Abstract

The present application relates to the field of concentration detection, and specifically to a kind of experimental drug concentration rapid determination instrument, including extraction assembly, centrifugal component and material taking assembly, the extraction assembly includes extraction cup, stirring assembly is installed in the inside of extraction cup, the stirring assembly includes with the outer stirring rod of extraction cup rotation connection, inner stirring rod and helical blade;It further includes scraping component, the scraping component includes with the inner scraper of helical blade sliding connection, with the middle scraper of inner stirring rod sliding connection and with the outer scraper of outer stirring rod sliding connection.The present application is integrated by stirring extraction and centrifugal purification function, without sample transfer, the degree of automation of high integration equipment, to solve the pain points of sample loss, pollution, cumbersome process, low degree of automation in the prior art, meet the efficient, accurate demand of pharmacokinetic experiment and all kinds of biological, chemical sample pretreatment, provide stable support for subsequent automatic material distribution, detection link.

Description

Technical Field

[0001] This invention relates to the field of concentration detection, and more specifically to a rapid drug concentration analyzer for laboratory use. Background Technology

[0002] In pharmacokinetic experiments, biological sample detection, and chemical extraction and separation, sample pretreatment is a crucial step affecting the accuracy and efficiency of test results. Its core requirement is to effectively separate the target analyte from impurities in the sample matrix (such as proteins, suspended particles, and emulsion layers) through extraction and purification operations, providing a high-purity sample for subsequent quantitative detection. Among these, stirred extraction and centrifugal purification are two key steps in sample pretreatment. Stirring accelerates the extraction system to reach equilibrium, improving the extraction efficiency of the target analyte; centrifugation thoroughly separates impurities from the supernatant in the extracted sample, removing interfering components.

[0003] Currently, existing technologies mostly implement stirring and centrifugation functions through separate equipment. That is, the extraction operation is first completed in a dedicated extraction vessel using a stirring device, and then the extracted sample is manually transferred to the centrifuge tube of the centrifuge equipment for centrifugation and purification. After centrifugation, the supernatant must be manually transferred again or through an additional transfer mechanism to the subsequent filtration and detection modules. This separate processing method has many technical defects and cannot meet the needs of automated, high-precision sample pretreatment.

[0004] First, sample transfer is prone to loss and contamination. This can cause samples to adhere to the inner walls of containers and in the transfer tubing, resulting in the loss of the target substance and affecting the accuracy of the test results. At the same time, improper operation or poor environmental control during the transfer process can easily introduce external contaminants or lead to cross-contamination between different samples, further interfering with the test results.

[0005] Secondly, the operation process is cumbersome and lacks automation. Separate equipment requires manual intervention in multiple steps, including vessel switching, sample transfer, and parameter adjustment. This not only increases the workload of researchers but also leads to poor experimental repeatability due to human error (such as differences in transfer speed and centrifugation timing), making it difficult to meet the requirements for standardized processing of batch samples. This inefficiency is particularly pronounced in pharmacokinetic experiments, where a large number of time-point samples need to be processed simultaneously.

[0006] Furthermore, the equipment suffers from poor connectivity and complex structure. Independent mixing, centrifuging, and transfer mechanisms require significant experimental space, and the interfaces between different devices are poorly compatible, making it difficult to integrate them into an automated closed-loop processing system. At the same time, when multiple devices work together, problems such as connection bottlenecks and parameter mismatches are prone to occur, increasing equipment maintenance costs and failure rates.

[0007] Therefore, it is necessary to invent a rapid drug concentration measuring instrument for laboratory use to solve the above problems. Summary of the Invention

[0008] The purpose of this invention is to provide a rapid drug concentration analyzer for laboratory use. By integrating stirring extraction and centrifugation purification functions, it is an integrated device with a high degree of automation that eliminates the need for sample transfer. This addresses the pain points of existing technologies, such as sample loss, contamination, cumbersome processes, and low automation. It meets the high-efficiency and accurate requirements of pharmacokinetic experiments and various biological and chemical sample pretreatment, and provides stable support for subsequent automatic dispensing and detection processes.

[0009] To achieve the above objectives, the present invention provides the following technical solution: a rapid drug concentration analyzer for laboratory use, comprising an extraction component, a centrifugation component, and a material handling component. The extraction component includes an extraction cup, and a stirring component is installed inside the extraction cup. The stirring component includes an outer stirring rod, an inner stirring rod, and a spiral blade that are rotatably connected to the extraction cup. It also includes a scraping assembly, which includes an inner scraper slidably connected to the spiral blade, a middle scraper slidably connected to the inner stirring rod, and an outer scraper slidably connected to the outer stirring rod. The centrifugation assembly includes a centrifugation cup, which is rotatably connected to an extraction cup. A convex plug is slidably connected inside the centrifugation cup. Both sides of the centrifugation cup are provided with a material handling assembly, each of which includes an extraction cup. One extraction cup is used to extract the clear liquid for testing, and the other extraction cup is used to store waste liquid.

[0010] In a preferred embodiment of the present invention, a first feed head and a second feed head are respectively connected and installed on both sides of the extraction cup, a base plate is fixedly connected to the bottom of the extraction cup, the top of the base plate is recessed, and the extraction cup and the centrifuge cup are made of quartz material.

[0011] As a preferred embodiment of the present invention, the stirring assembly further includes a protective box, which is installed on the top of the extraction cup. A motor is fixedly installed inside the protective box, and the output end of the motor is fixedly connected to a driving bevel gear via a coupling. An i-shaped bracket is fixedly installed on the other side inside the protective box. A driven lower bevel gear is rotatably connected to the bottom inside the i-shaped bracket, and a driven upper bevel gear is rotatably connected to the upper inside the i-shaped bracket. The upper and lower sides of the driving bevel gear are respectively engaged with the driven lower bevel gear and the driven upper bevel gear.

[0012] In a preferred embodiment of the present invention, an outer rotating cylinder is fixedly connected to the bottom end of the driven lower bevel tooth, the outer rotating cylinder is rotatably connected to the C-shaped bracket, an inner rotating cylinder is fixedly connected to the inside of the driven upper bevel tooth, the inner rotating cylinder is rotatably connected to the C-shaped bracket, and the inner rotating cylinder passes through the outer rotating cylinder and is rotatably connected inside the outer rotating cylinder.

[0013] In a preferred embodiment of the present invention, the bottom of the inner rotating cylinder is fixedly connected to the inner stirring rod, the inner stirring rod is fixedly connected to the spiral blade, the bottom of the outer rotating cylinder is fixedly connected to the outer stirring rod, the outer side of the outer rotating cylinder is fitted with a bearing connected to the extraction cup, the top of the protective box is fixedly installed with an electric push rod, the output end of the electric push rod is fixedly connected to an inner rod, the inner rod passes through the inner rotating cylinder and is slidably connected to the inner rotating cylinder, and the inner rod is rotatably connected to the inner scraper.

[0014] As a preferred embodiment of the present invention, the inner scraper has an inner scraping groove that is slidably connected to the spiral blade, the middle scraper has a middle scraping groove that is slidably connected to the inner stirring rod, the outer scraper has an outer scraping groove that is slidably connected to the outer stirring rod, and an outer scraping ring is fixedly connected to the outer side of the outer scraper.

[0015] In a preferred embodiment of the present invention, the outer side of the inner scraper is provided with an inner groove, the inner side of the middle scraper is fixedly connected with an inner convex ring that mates with the inner groove, the outer side of the middle scraper is provided with an outer groove, and the inner side of the outer scraper is fixedly connected with an outer convex ring that mates with the outer groove.

[0016] In a preferred embodiment of the present invention, the centrifuge assembly further includes a base, a servo motor installed inside the base, the output end of the servo motor being fixedly connected to the centrifuge cup via a coupling, two mounting brackets fixedly connected to the top of the base, the two mounting brackets being distributed on both sides of the centrifuge cup and fixedly connected to the extraction cup, liquid outlet grooves being opened on both sides of the interior of the centrifuge cup, a bearing ring being connected between the centrifuge cup and the extraction cup, the top of the convex plug being tapered, a fixing plug being fixedly connected to the top of the convex plug, a cavity being opened inside the fixing plug, a cylindrical block being installed inside the cavity, a fixing rod being fixedly connected to the top of the cylindrical block, and the rising fixing rod being fixedly connected to the inner rod.

[0017] In a preferred embodiment of the present invention, a handle is fixedly connected to the outer side of each extraction cup, and a liquid injection tube communicating with the extraction cup is fixedly connected to the inner side of each extraction cup. A baffle is fixedly connected to the outer side of the liquid injection tube. A fixed tube is fixedly connected to the inside of the liquid outlet groove. An arc-shaped groove is provided on the inner side of the outer end of the fixed tube. A blocking bead is provided inside the arc-shaped groove. A telescopic rod is connected between the inner side of the blocking bead and the inner wall of the fixed tube. An elastic element is sleeved on the outer side of the telescopic rod. An inlet is opened on the inner side of the fixed tube.

[0018] In a preferred embodiment of the present invention, a concentration measurement module is installed inside the extraction cup used for detection.

[0019] Compared with the prior art, the technical effects and advantages provided by the present invention in the above technical solution are as follows: By cooperating with the stirring and scraping components, after stirring is completed, the electric actuator is activated to extend the inner rod, which in turn drives the inner scraper to descend. Since the inner scraper, middle scraper, and inner rod rotate relative to each other, the middle scraper and outer scraper can descend synchronously. At the same time, the inner scraping groove inside the inner scraper cooperates with the spiral blade, so the inner scraper can rotate with the shape of the spiral blade when it descends. The middle scraping groove inside the middle scraper cooperates with the inner stirring rod, and the outer scraping groove inside the outer scraper cooperates with the outer stirring rod. When the middle and outer scrapers descend, they can scrape the outer walls of the outer and inner stirring rods. The outer scraping ring scrapes the inside of the extraction cup, which can reduce water droplets adhering to the wall. During the upward movement, the convex plug returns to its original position and rises. The convex plug can scrape the inner wall of the centrifuge cup to prevent impurities from remaining on the inner wall. Extraction and separation and extraction detection are carried out in an integrated manner. No position transfer is required during the process. It has a high degree of automation and high efficiency, and can reduce solution loss and prevent contamination.

[0020] The system is modularized, requiring less human intervention, which improves efficiency and accuracy, while also being low-cost and facilitating increased profitability. Attached Figure Description

[0021] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this invention. For those skilled in the art, other drawings can be obtained based on these drawings.

[0022] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 This is a cross-sectional structural diagram of the present invention; Figure 3 This is a schematic diagram of the internal structure of the extraction cup of the present invention; Figure 4 For the present invention Figure 3 Enlarged structural diagram at point A in the middle; Figure 5 This is a schematic diagram of the connection structure between the stirring assembly and the scraping assembly of the present invention; Figure 6 For the present invention Figure 5 Enlarged structural diagram at point B; Figure 7 This is an exploded structural diagram of the scraping assembly of the present invention; Figure 8 This is an exploded structural diagram of the stirring assembly of the present invention; Figure 9 This is a schematic cross-sectional view of the scraping assembly of the present invention; Figure 10 For the present invention Figure 9 Enlarged structural diagram at point C; Figure 11 This is a schematic diagram of the extraction cup and centrifuge cup of the present invention; Figure 12 This is a schematic diagram of the three-dimensional structure of the extraction cup of the present invention; Figure 13 This is a schematic diagram of the cross-sectional structure of the fixed tube of the present invention.

[0023] Explanation of reference numerals in the attached figures: 001. Extraction assembly; 002. Stirring assembly; 003. Scraping assembly; 004. Centrifugation assembly; 005. Material handling assembly; 101. Extraction cup; 102. First feed head; 103. Second feed head; 104. Base plate; 105. Bearing ring; 201. Protective box; 202. Outer stirring rod; 203. Inner stirring rod; 204. Spiral blade; 205. Active conical tooth; 206. C-shaped support; 207. Driven lower conical tooth; 208. Driven upper conical tooth; 209. Outer rotating cylinder; 210. Inner rotating cylinder; 301. Inner scraper; 302. Middle scraper; 303. Outer scraper; 304. Electric push rod; 305. Inner rod; 306. Inner scraper groove; 307. Middle scraper groove; 308. Outer scraper groove; 309. Outer scraper ring; 310. Inner groove; 311. Inner convex ring; 312. Outer groove; 313. Outer convex ring; 401. Base; 402. Servo motor; 403. Centrifuge cup; 404. Mounting bracket; 405. Liquid outlet tank; 406. Convex plug; 407. Fixed plug; 408. Cavity; 409. Cylindrical block; 410. Fixing rod; 501. Extraction cup; 502. Handle; 503. Injection tube; 504. Baffle; 505. Fixing tube; 506. Arc groove; 507. Blocking bead; 508. Telescopic rod; 509. Elastic element; 510. Inlet. Detailed Implementation

[0024] To enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0025] This invention provides, for example Figure 1-13 The experimental drug concentration rapid determination instrument shown includes an extraction component 001, a centrifugation component 004 and a material handling component 005. The extraction component 001 includes an extraction cup 101. A stirring component 002 is installed inside the extraction cup 101. The stirring component 002 includes an outer stirring rod 202, an inner stirring rod 203 and a spiral blade 204 that are rotatably connected to the extraction cup 101. It also includes a scraper assembly 003, which includes an inner scraper 301 slidably connected to the spiral blade 204, a middle scraper 302 slidably connected to the inner stirring rod 203, and an outer scraper 303 slidably connected to the outer stirring rod 202. The centrifugation assembly 004 includes a centrifugation cup 403, which is rotatably connected to an extraction cup 101. A convex plug 406 is slidably connected inside the centrifugation cup 403. Both sides of the centrifugation cup 403 are provided with a material taking assembly 005, each of which includes an extraction cup 501. One extraction cup 501 is used to extract the clear liquid for testing, and the other extraction cup 501 is used to store the waste liquid.

[0026] As a further optimization of the present invention, a first feed head 102 and a second feed head 103 are respectively connected and installed on both sides of the extraction cup 101, and a bottom plate 104 is fixedly connected to the bottom of the extraction cup 101. The top of the bottom plate 104 is recessed. The extraction cup 101 and the centrifuge cup 403 are made of transparent quartz material. First, the sample to be tested and the extractant are manually injected into the extraction cup 101 in proportion through the first feed head 102 and the second feed head 103. The bottom plate 104 has a concave top to facilitate the automatic collection and discharge of the solution during output. The quartz material is an inert material to prevent it from reacting with the solution. The transparent material makes it easy to observe the situation at any time, and all of them are equipped with scale lines inside.

[0027] In a further optimization of the above embodiment, the stirring assembly 002 also includes a protective box 201. The protective box 201 is installed on the top of the extraction cup 101. A motor is fixedly installed inside the protective box 201. The output end of the motor is fixedly connected to the active bevel gear 205 through a coupling. A chamfered bracket 206 is fixedly installed on the other side inside the protective box 201. A driven lower bevel gear 207 is rotatably connected to the bottom inside the chamfered bracket 206. A driven upper bevel gear 208 is rotatably connected to the upper inside the chamfered bracket 206. The upper and lower sides of the active bevel gear 205 are respectively engaged with the driven lower bevel gear 207 and the driven upper bevel gear 208. An outer rotating cylinder 209 is fixedly connected to the bottom end of the driven lower conical tooth 207. The outer rotating cylinder 209 is rotatably connected to the C-shaped support 206. An inner rotating cylinder 210 is fixedly connected inside the driven upper conical tooth 208. The inner rotating cylinder 210 is rotatably connected to the C-shaped support 206. The inner rotating cylinder 210 passes through the outer rotating cylinder 209 and is rotatably connected inside the outer rotating cylinder 209. The bottom of the inner rotating cylinder 210 is fixedly connected to the inner stirring rod 203. An outer stirring rod 202 is fixedly connected to the bottom of the outer rotating cylinder 209, which is fixedly connected to the spiral blade 204. A bearing connected to the extraction cup 101 is sleeved on the outer side of the outer rotating cylinder 209. An electric push rod 304 is fixedly installed on the top of the protective box 201. An inner rod 305 is fixedly connected to the output end of the electric push rod 304. The inner rod 305 passes through the inner rotating cylinder 210 and is slidably connected to the inner rotating cylinder 210. The outer side of the inner rod 305 is rotatably connected to the inner scraper 301.

[0028] First, the sample and extractant are stirred and mixed. By starting the motor, the motor drives the active bevel gear 205 to rotate, which in turn drives the driven lower bevel gear 207 and driven upper bevel gear 208 to rotate. The driven lower bevel gear 207 and driven upper bevel gear 208 rotate in opposite directions. The driven lower bevel gear 207 drives the outer stirring rod 202 to rotate clockwise through the outer rotating cylinder 209. The driven upper bevel gear 208 drives the inner stirring rod 203 to rotate counterclockwise through the inner rotating cylinder 210. The inner rotating cylinder 210 passes through the outer rotating cylinder 209 and the driven lower bevel gear 207, thus not hindering the rotation of the outer stirring rod 202. The inner stirring rod 203 drives the spiral blade 204 to rotate synchronously. The inner stirring rod 203 rotates in opposite directions to the outer stirring rod 202. Through multi-directional stirring and mixing with the spiral blade 204, the mixing efficiency can be improved. Furthermore, the inner rotating cylinder 210 and the driven upper bevel gear 208 have through holes for the inner rod 305 to pass through.

[0029] In the above structure, the inner scraper 301 has an inner scraping groove 306 that is slidably connected to the spiral blade 204, the middle scraper 302 has a middle scraping groove 307 that is slidably connected to the inner stirring rod 203, the outer scraper 303 has an outer scraping groove 308 that is slidably connected to the outer stirring rod 202, and an outer scraping ring 309 is fixedly connected to the outer side of the outer scraper 303; the inner scraper 301 has an inner groove 310 on its outer side, the middle scraper 302 has an inner protruding ring 311 that mates with the inner groove 310 fixedly connected to its inner side, the middle scraper 302 has an outer groove 312 on its outer side, and the outer scraper 303 has an outer protruding ring 313 that mates with the outer groove 312 fixedly connected to its inner side.

[0030] When stirring is in progress, the scraper assembly 003 is located inside the extraction cup 101 near the top. The outer stirring rod 202 drives the outer scraper 303 to rotate, and the inner stirring rod 203 drives the middle scraper 302 to rotate. The inner scraper 301 and the spiral blade 204 move synchronously. The outer convex ring 313 rotates inside the outer groove 312 for easy positioning, and the inner convex ring 311 rotates inside the inner groove 310 to ensure that the outer stirring rod 202, the inner stirring rod 203, and the spiral blade 204 do not interfere with each other during rotation. After stirring, the material can be scraped by the scraper assembly 003. After stirring is complete, the electric actuator 304 drives the inner rod 305 to extend, and the inner rod 305 drives the inner scraper 301 to descend. Since the inner scraper 301, the middle scraper 302 and the inner rod 305 rotate relative to each other, the middle scraper 302 and the outer scraper 303 can be driven to descend synchronously. At the same time, the inner scraping groove 306 inside the inner scraper 301 cooperates with the spiral blade 204. When the inner scraper 301 descends, it can rotate with the shape of the spiral blade 204. The middle scraping groove 307 inside the middle scraper 302 cooperates with the inner stirring rod 203, and the outer scraping groove 308 inside the outer scraper 303 cooperates with the outer stirring rod 202. When the middle scraper 302 and the outer scraper 303 descend, they can scrape the material from the outer wall of the outer stirring rod 202 and the inner stirring rod 203. The outer scraping ring 309 scrapes the material from the inside of the extraction cup 101, which can reduce water droplets adhering to the wall.

[0031] As a further optimization of the present invention, the centrifuge assembly 004 also includes a base 401, a servo motor 402 is installed inside the base 401, the output end of the servo motor 402 is fixedly connected to the centrifuge cup 403 via a coupling, two mounting brackets 404 are fixedly connected to the top of the base 401, the two mounting brackets 404 are distributed on both sides of the centrifuge cup 403 and fixedly connected to the extraction cup 101, liquid outlet grooves 405 are opened on both sides of the centrifuge cup 403, a bearing ring 105 is connected between the centrifuge cup 403 and the extraction cup 101, the top of the convex plug 406 is tapered, a fixing plug 407 is fixedly connected to the top of the convex plug 406, a cavity 408 is opened inside the fixing plug 407, a cylindrical block 409 is installed inside the cavity 408, a fixing rod 410 is fixedly connected to the top of the cylindrical block 409, and the rising fixing rod 410 is fixedly connected to the inner rod 305.

[0032] As the inner rod 305 drives the inner scraper 301 to descend, it also drives the convex plug 406 to descend. When the fixed plug 407 moves away from the bottom plate 104, the extraction cup 101 is connected to the centrifuge cup 403. Under the downward pressure of the inner scraper 301, the middle scraper 302 and the outer scraper 303, the solution inside the extraction cup 101 is continuously squeezed into the centrifuge cup 403. When the inner scraper 301 descends to contact the bottom plate 104, the convex plug 406 descends to the bottom of the centrifuge cup 403. At this time, the servo motor 402 is started, and the servo motor 402 drives the centrifuge cup 403 to rotate. The centrifuge cup 403 centrifuges and separates the solution inside. After separation, it is allowed to stand, so that the internal impurities precipitate. After precipitation, it is divided into an upper clear liquid and a lower precipitate. The upper clear liquid is mainly the sample liquid, and the lower precipitate is the impurities in the sample.

[0033] During centrifugation, the centrifuge cup 403 is rotatably connected to the extraction cup 101 via the bearing ring 105. The centrifuge cup 403 drives the convex plug 406 to rotate outside the cylindrical block 409. After centrifugation, the centrifuge cup 403 is reset so that the two liquid outlets 405 are aligned with the two mounting brackets 404 respectively.

[0034] In a further optimization of the above embodiment, the extraction cup 501 has a glass window on its side wall, and the outer glass window has scale lines for easy observation of the internal liquid level. The outer side of the extraction cup 501 is fixedly connected to a handle 502. The inner side of the extraction cup 501 is fixedly connected to a liquid injection pipe 503 communicating with the extraction cup 501. The outer side of the liquid injection pipe 503 is fixedly connected to a baffle 504. The inside of the liquid outlet 405 is fixedly connected to a fixed pipe 505. The inner side of the outer end of the fixed pipe 505 is provided with an arc-shaped groove 506. The inside of the arc-shaped groove 506 is provided with a blocking bead 507. The inner side of the blocking bead 507 is connected to the inner wall of the fixed pipe 505 with a telescopic rod 508. The outer side of the telescopic rod 508 is sleeved with an elastic element 509. The inner side of the fixed pipe 505 is provided with a liquid inlet 510. The extraction cup 501 used for detection is equipped with a concentration measurement module.

[0035] When testing is required, the user places the extraction cup 501, used for extracting the clear liquid for testing, into the mounting bracket 404 on the left, so that the injection tube 503 is inserted into the fixed tube 505. The injection tube 503 pushes the blocking bead 507 away from the arc groove 506, so that the centrifuge cup 403 is connected to the extraction cup 501. Then, the electric push rod 304 is activated to drive the inner scraper 301 and the convex plug 406 to reset and rise. The convex plug 406 can scrape the inner wall of the centrifuge cup 403 to prevent impurities from remaining on the inner wall. The clear liquid inside enters the inlet 510 through the outlet groove 405 and enters the injection tube 503 through the fixed tube 505 for extraction. The extraction cup 501 used for extracting the clear liquid for testing is equipped with a filter screen for further filtration and purification of the clear liquid. The filtered clear liquid enters the extraction cup 501 used for extracting the clear liquid for testing. Then, the detection module on the side of the extraction cup 501 is activated to detect the concentration, and then the detection result is uploaded to the detection system.

[0036] When the extraction cup 501 enters the mounting frame 404, both sides of the extraction cup 501 are in contact with the inner wall of the mounting frame 404. The concentration measurement module includes an external light source component and a light receiving component located on both sides of the mounting frame 404. The external light source component and the light receiving component correspond to the glass windows on both sides of the extraction cup 501. The external light source component is equipped with a focusing lens to ensure that the ultraviolet light penetrates the clear liquid in the cup in a parallel beam. At the same time, the opaque part of the extraction cup 501 naturally serves as a light shield to avoid interference from ambient light. The light receiving component is located on the other side of the extraction cup 501 and is aligned with the optical axis of the ultraviolet lamp to ensure stable reception of transmitted light. The intensity of the detected light is converted by the light receiving unit through a signal processor, and the electrical signal is converted into concentration data value by a data processor and presented.

[0037] After the clear liquid is extracted, the valve inside the extraction cup 501 used for extracting the clear liquid for testing is closed, and the valve inside the extraction cup 501 used for storing waste liquid is opened, so that the solution containing impurities at the bottom of the centrifuge cup 403 enters the interior of the extraction cup 501 through another liquid outlet 405. When the fixed plug 407 is inserted into the bottom plate 104, the convex plug 406 continues to rise, which can squeeze the solution inside out and enter the extraction cup 501 for storing waste liquid for storage. All of the above electrical components are connected to and controlled by the PLC processor. The stirring speed and time, as well as the centrifugation speed and time, can be controlled by the program as needed to improve efficiency.

[0038] The foregoing has only described certain exemplary embodiments of the present invention by way of illustration. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the foregoing drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A rapid drug concentration analyzer for laboratory use, comprising an extraction component (001), a centrifugation component (004), and a material handling component (005), characterized in that: The extraction assembly (001) includes an extraction cup (101), and a stirring assembly (002) is installed inside the extraction cup (101). The stirring assembly (002) includes an outer stirring rod (202), an inner stirring rod (203), and a spiral blade (204) that are rotatably connected to the extraction cup (101). It also includes a scraper assembly (003), which includes an inner scraper (301) slidably connected to the spiral blade (204), a middle scraper (302) slidably connected to the inner stirring rod (203), and an outer scraper (303) slidably connected to the outer stirring rod (202). The centrifuge assembly (004) includes a centrifuge cup (403), which is rotatably connected to an extraction cup (101). A convex plug (406) is slidably connected inside the centrifuge cup (403). Both sides of the centrifuge cup (403) are provided with a material taking assembly (005), and each material taking assembly (005) includes an extraction cup (501). One extraction cup (501) is used to extract the clear liquid for testing, and the other extraction cup (501) is used to store the waste liquid.

2. The rapid drug concentration analyzer for laboratory use according to claim 1, characterized in that: The extraction cup (101) is connected to a first feed head (102) and a second feed head (103) on both sides respectively. The bottom of the extraction cup (101) is fixedly connected to a base plate (104). The top of the base plate (104) is recessed. The extraction cup (101) and the centrifuge cup (403) are made of quartz material.

3. The rapid drug concentration analyzer for laboratory use according to claim 1, characterized in that: The stirring assembly (002) also includes a protective box (201), which is installed on the top of the extraction cup (101). A motor is fixedly installed inside the protective box (201), and the output end of the motor is fixedly connected to a driving bevel gear (205) via a coupling. A U-shaped bracket (206) is fixedly installed on the other side inside the protective box (201). A driven lower bevel gear (207) is rotatably connected to the bottom inside the U-shaped bracket (206), and a driven upper bevel gear (208) is rotatably connected to the upper inside the U-shaped bracket (206). The upper and lower sides of the driving bevel gear (205) are respectively engaged with the driven lower bevel gear (207) and the driven upper bevel gear (208).

4. The rapid drug concentration analyzer for laboratory use according to claim 3, characterized in that: The bottom end of the driven lower bevel tooth (207) is fixedly connected to an outer rotating cylinder (209), the outer rotating cylinder (209) is rotatably connected to the C-shaped bracket (206), the inner rotating cylinder (210) is fixedly connected to the inside of the driven upper bevel tooth (208), the inner rotating cylinder (210) is rotatably connected to the C-shaped bracket (206), the inner rotating cylinder (210) passes through the outer rotating cylinder (209) and is rotatably connected inside the outer rotating cylinder (209).

5. The rapid drug concentration analyzer for laboratory use according to claim 4, characterized in that: The bottom of the inner rotating cylinder (210) is fixedly connected to the inner stirring rod (203), the inner stirring rod (203) is fixedly connected to the spiral blade (204), the bottom of the outer rotating cylinder (209) is fixedly connected to the outer stirring rod (202), the outer side of the outer rotating cylinder (209) is fitted with a bearing connected to the extraction cup (101), the top of the protective box (201) is fixedly installed with an electric push rod (304), the output end of the electric push rod (304) is fixedly connected to an inner rod (305), the inner rod (305) passes through the inner rotating cylinder (210) and is slidably connected to the inner rotating cylinder (210), and the inner rod (305) is rotatably connected to the inner scraper (301).

6. The rapid drug concentration analyzer for laboratory use according to claim 5, characterized in that: The inner scraper (301) has an inner scraping groove (306) that is slidably connected to the spiral blade (204). The middle scraper (302) has a middle scraping groove (307) that is slidably connected to the inner stirring rod (203). The outer scraper (303) has an outer scraping groove (308) that is slidably connected to the outer stirring rod (202). An outer scraping ring (309) is fixedly connected to the outer side of the outer scraper (303).

7. The rapid drug concentration analyzer for laboratory use according to claim 6, characterized in that: The inner scraper (301) has an inner groove (310) on its outer side, and the middle scraper (302) has an inner convex ring (311) that cooperates with the inner groove (310) fixedly connected to its inner side. The middle scraper (302) has an outer groove (312) on its outer side, and the outer scraper (303) has an outer convex ring (313) that cooperates with the outer groove (312) fixedly connected to its inner side.

8. The rapid drug concentration analyzer for laboratory use according to claim 1, characterized in that: The centrifuge assembly (004) also includes a base (401), inside which a servo motor (402) is installed. The output end of the servo motor (402) is fixedly connected to the centrifuge cup (403) via a coupling. Two mounting brackets (404) are fixedly connected to the top of the base (401). The two mounting brackets (404) are distributed on both sides of the centrifuge cup (403) and fixedly connected to the extraction cup (101). Liquid outlet grooves (405) are opened on both sides of the interior of the centrifuge cup (403). A bearing ring (105) is connected between the centrifuge cup (403) and the extraction cup (101). The top of the convex plug (406) is tapered. A fixing plug (407) is fixedly connected to the top of the convex plug (406). A cavity (408) is opened inside the fixing plug (407). A cylindrical block (409) is installed inside the cavity (408). A fixing rod (410) is fixedly connected to the top of the cylindrical block (409). The rising fixing rod (410) is fixedly connected to the inner rod (305).

9. The rapid drug concentration analyzer for laboratory use according to claim 8, characterized in that: A handle (502) is fixedly connected to the outside of the extraction cup (501). A liquid injection tube (503) communicating with the extraction cup (501) is fixedly connected to the inside of the extraction cup (501). A baffle (504) is fixedly connected to the outside of the liquid injection tube (503). A fixed tube (505) is fixedly connected to the inside of the liquid outlet groove (405). An arc-shaped groove (506) is provided on the inner side of the outer end of the fixed tube (505). A blocking bead (507) is provided inside the arc-shaped groove (506). A telescopic rod (508) is connected between the inner side of the blocking bead (507) and the inner wall of the fixed tube (505). An elastic element (509) is sleeved on the outside of the telescopic rod (508). An inlet (510) is opened on the inner side of the fixed tube (505).

10. The rapid drug concentration analyzer for laboratory use according to claim 1, characterized in that: The extraction cup (501) used for detection is equipped with a concentration measurement module.

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